Proteins > Corticosteroid 11-beta-dehydrogenase isozyme 1
Page last updated: 2024-08-07 13:02:40
Corticosteroid 11-beta-dehydrogenase isozyme 1
An 11-beta-hydroxysteroid dehydrogenase 1 that is encoded in the genome of rat. [OMA:P16232, PRO:DNx]
Synonyms
EC 1.1.1.146;
11-beta-hydroxysteroid dehydrogenase 1;
11-DH;
11-beta-HSD1
Research
Bioassay Publications (4)
| Timeframe | Studies on this Protein(%) | All Drugs % |
|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 3 (75.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Compounds (4)
Drugs with Inhibition Measurements
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|
| glycyrrhetinic acid | Rattus norvegicus (Norway rat) | IC50 | 0.0900 | 1 | 1 |
| erlotinib | Rattus norvegicus (Norway rat) | IC50 | 0.0300 | 1 | 1 |
| hylin | Rattus norvegicus (Norway rat) | IC50 | 0.2920 | 1 | 2 |
Drugs with Activation Measurements
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|
| pf 915275 | Rattus norvegicus (Norway rat) | EC50 | 14.5000 | 1 | 1 |