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clonidine and Dysautonomia, Familial

clonidine has been researched along with Dysautonomia, Familial in 3 studies

Clonidine: An imidazoline sympatholytic agent that stimulates ALPHA-2 ADRENERGIC RECEPTORS and central IMIDAZOLINE RECEPTORS. It is commonly used in the management of HYPERTENSION.
clonidine (amino form) : A clonidine that is 4,5-dihydro-1H-imidazol-2-amine in which one of the amino hydrogens is replaced by a 2,6-dichlorophenyl group.

Dysautonomia, Familial: An autosomal disorder of the peripheral and autonomic nervous systems limited to individuals of Ashkenazic Jewish descent. Clinical manifestations are present at birth and include diminished lacrimation, defective thermoregulation, orthostatic hypotension (HYPOTENSION, ORTHOSTATIC), fixed pupils, excessive SWEATING, loss of pain and temperature sensation, and absent reflexes. Pathologic features include reduced numbers of small diameter peripheral nerve fibers and autonomic ganglion neurons. (From Adams et al., Principles of Neurology, 6th ed, p1348; Nat Genet 1993;4(2):160-4)

Research Excerpts

ExcerptRelevanceReference
"Patients with familial dysautonomia (FD) frequently experience hypertensive crises after gastrostomy feeding."2.71Clonidine improves postprandial baroreflex control in familial dysautonomia. ( Axelrod, FB; Berlin, D; Brown, CM; Brys, M; Hecht, MJ; Hilz, MJ; Marthol, H; Tutaj, M, 2003)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (33.33)18.2507
2000's1 (33.33)29.6817
2010's1 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Spalink, CL1
Barnes, E1
Palma, JA1
Norcliffe-Kaufmann, L1
Kaufmann, H1
Marthol, H1
Tutaj, M1
Brys, M1
Brown, CM1
Hecht, MJ1
Berlin, D1
Axelrod, FB1
Hilz, MJ1
Cortelli, P1
Parchi, P1
Contin, M1
Pierangeli, G1
Avoni, P1
Tinuper, P1
Montagna, P1
Baruzzi, A1
Gambetti, PL1
Lugaresi, E1

Trials

1 trial available for clonidine and Dysautonomia, Familial

ArticleYear
Clonidine improves postprandial baroreflex control in familial dysautonomia.
    European journal of clinical investigation, 2003, Volume: 33, Issue:10

    Topics: Adolescent; Adrenergic alpha-Agonists; Baroreflex; Blood Pressure; Child; Clonidine; Dysautonomia, F

2003

Other Studies

2 other studies available for clonidine and Dysautonomia, Familial

ArticleYear
Intranasal dexmedetomidine for adrenergic crisis in familial dysautonomia.
    Clinical autonomic research : official journal of the Clinical Autonomic Research Society, 2017, Volume: 27, Issue:4

    Topics: Administration, Intranasal; Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Agonists; Adult;

2017
Cardiovascular dysautonomia in fatal familial insomnia.
    Clinical autonomic research : official journal of the Clinical Autonomic Research Society, 1991, Volume: 1, Issue:1

    Topics: Adult; Autonomic Nervous System; Blood Pressure; Cardiovascular System; Clonidine; Dysautonomia, Fam

1991