dihydroxyphenylalanine has been researched along with Dysautonomia, Familial in 4 studies
Dihydroxyphenylalanine: A beta-hydroxylated derivative of phenylalanine. The D-form of dihydroxyphenylalanine has less physiologic activity than the L-form and is commonly used experimentally to determine whether the pharmacological effects of LEVODOPA are stereospecific.
dopa : A hydroxyphenylalanine carrying hydroxy substituents at positions 3 and 4 of the benzene ring.
Dysautonomia, Familial: An autosomal disorder of the peripheral and autonomic nervous systems limited to individuals of Ashkenazic Jewish descent. Clinical manifestations are present at birth and include diminished lacrimation, defective thermoregulation, orthostatic hypotension (HYPOTENSION, ORTHOSTATIC), fixed pupils, excessive SWEATING, loss of pain and temperature sensation, and absent reflexes. Pathologic features include reduced numbers of small diameter peripheral nerve fibers and autonomic ganglion neurons. (From Adams et al., Principles of Neurology, 6th ed, p1348; Nat Genet 1993;4(2):160-4)
| Excerpt | Relevance | Reference |
|---|---|---|
| "This study tested whether familial dysautonomia (FD) involves progressive loss of noradrenergic nerves." | 1.35 | Plasma catechols in familial dysautonomia: a long-term follow-up study. ( Axelrod, FB; Goldstein, DS; Holmes, C, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (50.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Goldstein, DS | 2 |
| Holmes, C | 2 |
| Axelrod, FB | 2 |
| Kopin, IJ | 1 |
| Guglielmi, L | 1 |
| Vecchi, L | 1 |
| Appenzeller, O | 1 |
| Goss, JE | 1 |
1 review available for dihydroxyphenylalanine and Dysautonomia, Familial
| Article | Year |
|---|---|
[Treatment of Parkinson's disease with L-dopa].
Topics: Arrhythmias, Cardiac; Basal Ganglia; Blood-Brain Barrier; Brain; Depression; Dihydroxyphenylalanine; | 1970 |
3 other studies available for dihydroxyphenylalanine and Dysautonomia, Familial
| Article | Year |
|---|---|
Plasma catechols in familial dysautonomia: a long-term follow-up study.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adult; Dihydroxyphenylalanine; Dopamine; Dysautonomia, Familial; Epi | 2008 |
Genotype and phenotype in familial dysautonomia.
Topics: Dihydroxyphenylalanine; Dopamine beta-Hydroxylase; Dysautonomia, Familial; Genes, Recessive; Genotyp | 1998 |
Autonomic deficits in Parkinson's syndrome.
Topics: Aged; Autonomic Nervous System; Blood Pressure; Body Temperature; Dihydroxyphenylalanine; Dysautonom | 1971 |