Page last updated: 2024-11-06

phentolamine and Dysautonomia, Familial

phentolamine has been researched along with Dysautonomia, Familial in 1 studies

Phentolamine: A nonselective alpha-adrenergic antagonist. It is used in the treatment of hypertension and hypertensive emergencies, pheochromocytoma, vasospasm of RAYNAUD DISEASE and frostbite, clonidine withdrawal syndrome, impotence, and peripheral vascular disease.
phentolamine : A substituted aniline that is 3-aminophenol in which the hydrogens of the amino group are replaced by 4-methylphenyl and 4,5-dihydro-1H-imidazol-2-ylmethyl groups respectively. An alpha-adrenergic antagonist, it is used for the treatment of hypertension.

Dysautonomia, Familial: An autosomal disorder of the peripheral and autonomic nervous systems limited to individuals of Ashkenazic Jewish descent. Clinical manifestations are present at birth and include diminished lacrimation, defective thermoregulation, orthostatic hypotension (HYPOTENSION, ORTHOSTATIC), fixed pupils, excessive SWEATING, loss of pain and temperature sensation, and absent reflexes. Pathologic features include reduced numbers of small diameter peripheral nerve fibers and autonomic ganglion neurons. (From Adams et al., Principles of Neurology, 6th ed, p1348; Nat Genet 1993;4(2):160-4)

Research Excerpts

ExcerptRelevanceReference
"Two populations of familial dysautonomia subjects are noted; those who like controls increase blood flow with iontophoresis of the alpha-antagonist and those who are refractory."1.30Assessing microcirculation in familial dysautonomia by laser Doppler flowmeter. ( Axelrod, FB; Bronfin, L; Hilz, MJ; Weiser, M, 1998)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Weiser, M1
Hilz, MJ1
Bronfin, L1
Axelrod, FB1

Other Studies

1 other study available for phentolamine and Dysautonomia, Familial

ArticleYear
Assessing microcirculation in familial dysautonomia by laser Doppler flowmeter.
    Clinical autonomic research : official journal of the Clinical Autonomic Research Society, 1998, Volume: 8, Issue:1

    Topics: Adolescent; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adult; Analysis of Variance; Ca

1998