fluorouracil has been researched along with Hemangioendothelioma in 2 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
Hemangioendothelioma: A neoplasm derived from blood vessels, characterized by numerous prominent endothelial cells that occur singly, in aggregates, and as the lining of congeries of vascular tubes or channels. Hemangioendotheliomas are relatively rare and are of intermediate malignancy (between benign hemangiomas and conventional angiosarcomas). They affect men and women about equally and rarely develop in childhood. (From Stedman, 25th ed; Holland et al., Cancer Medicine, 3d ed, p1866)
| Excerpt | Relevance | Reference |
|---|---|---|
| "A case of primary hemangioendothelioma is presented." | 1.26 | Primary malignant hemangioendothelioma of the liver: survival following nonoperative treatment. ( El-Mahdi, A; Langley, JR; Rosato, FE, 1978) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Langley, JR | 1 |
| Rosato, FE | 1 |
| El-Mahdi, A | 1 |
| Holley, MP | 1 |
| Cuschieri, A | 1 |
2 other studies available for fluorouracil and Hemangioendothelioma
| Article | Year |
|---|---|
Primary malignant hemangioendothelioma of the liver: survival following nonoperative treatment.
Topics: Fluorouracil; Hemangioendothelioma; Humans; Liver Neoplasms; Male; Middle Aged; Optic Neuritis | 1978 |
Epithelioid haemangioendothelioma of the liver: objective response to hepatic intra-arterial 5-FU.
Topics: Female; Fluorouracil; Hemangioendothelioma; Hepatic Artery; Humans; Injections, Intra-Arterial; Lapa | 1989 |