penicillin g has been researched along with Gas Gangrene in 35 studies
Penicillin G: A penicillin derivative commonly used in the form of its sodium or potassium salts in the treatment of a variety of infections. It is effective against most gram-positive bacteria and against gram-negative cocci. It has also been used as an experimental convulsant because of its actions on GAMMA-AMINOBUTYRIC ACID mediated synaptic transmission.
benzylpenicillin : A penicillin in which the substituent at position 6 of the penam ring is a phenylacetamido group.
Gas Gangrene: A severe condition resulting from bacteria invading healthy muscle from adjacent traumatized muscle or soft tissue. The infection originates in a wound contaminated with bacteria of the genus CLOSTRIDIUM. C. perfringens accounts for the majority of cases (over eighty percent), while C. noyvi, C. septicum, and C. histolyticum cause most of the other cases.
| Excerpt | Relevance | Reference |
|---|---|---|
| " In contrast, clindamycin was highly effective over a broad dosing range (8." | 5.27 | Comparison of clindamycin, rifampin, tetracycline, metronidazole, and penicillin for efficacy in prevention of experimental gas gangrene due to Clostridium perfringens. ( Laine, BM; Maier, KA; Mitten, JE; Stevens, DL, 1987) |
| " However, vancomycin and fosfomycin, which revealed suboptimal in vitro bactericidal activity, proved as efficacious as penicillin G and imipenem in an experimental mode of murine gas gangrene." | 3.67 | Clostridium perfringens type A. Comparison of in vitro and in vivo activity of twelve antimicrobial drugs. ( Traub, WH, 1986) |
| "Five antimicrobial drugs (ciprofloxacin, clindamycin, imipenem, penicillin G, and rifampin) were examined for therapeutic efficacy in a murine model gas gangrene due to Clostridium perfringens type A, following infection with large bacterial inocula." | 3.67 | Chemotherapy of experimental (murine) Clostridium perfringens type A gas gangrene. ( Traub, WH, 1988) |
| " In contrast, clindamycin was highly effective over a broad dosing range (8." | 1.27 | Comparison of clindamycin, rifampin, tetracycline, metronidazole, and penicillin for efficacy in prevention of experimental gas gangrene due to Clostridium perfringens. ( Laine, BM; Maier, KA; Mitten, JE; Stevens, DL, 1987) |
| "Post-traumatic and surgical aetiologies predominate, giving rise to two types of gangrene: clostridial gas gangrene secondary to contamined wounds, with a quasi-constant vascular element, affecting predominantly the limbs, and nonclostridrial gangrene, the increasing prevalence of which involves essentially spetic abdomino-pelvic surgery." | 1.26 | [Current aspects of gas gangrene, apropos of 47 cases collected over a 3-year period (1974-1976)]. ( Beaucaire, G; Chopin, C; Crasquin, O; Durocher, A; Gosselin, B; Wattel, F, 1977) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 31 (88.57) | 18.7374 |
| 1990's | 4 (11.43) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Unsworth, IP | 4 |
| Sharp, PA | 1 |
| Gehanno, P | 1 |
| Saint-Guily, JL | 1 |
| Régnier, B | 1 |
| Vachon, F | 2 |
| Nakae, H | 1 |
| Endo, S | 1 |
| Yamada, Y | 1 |
| Takakuwa, T | 1 |
| Taniguchi, S | 1 |
| Kikuchi, M | 1 |
| Stevens, DL | 3 |
| Bryant, AE | 1 |
| Adams, K | 1 |
| Mader, JT | 1 |
| Takahashi, H | 1 |
| Virenque, C | 1 |
| Wattel, F | 1 |
| Gosselin, B | 1 |
| Chopin, C | 1 |
| Durocher, A | 1 |
| Crasquin, O | 1 |
| Beaucaire, G | 1 |
| Rubinstein, E | 1 |
| Garrod, LP | 1 |
| Hitchcock, CR | 1 |
| Demello, FJ | 1 |
| Haglin, JJ | 1 |
| Erttmann, M | 1 |
| Hobrecht, R | 1 |
| Havemann, D | 1 |
| Traub, WH | 2 |
| Maier, KA | 1 |
| Laine, BM | 2 |
| Mitten, JE | 2 |
| Turnbull, TL | 1 |
| Cline, KS | 1 |
| Shah, MS | 1 |
| Nabong, R | 1 |
| Rogin, A | 1 |
| Zarif, A | 1 |
| Javadpour, N | 1 |
| Sassoon, H | 1 |
| Bush, IM | 1 |
| Klose, F | 3 |
| Schallehn, G | 3 |
| Roemer, GB | 1 |
| Freeman, WA | 1 |
| McFadzean, JA | 1 |
| Whelan, JP | 1 |
| Poliak, MS | 2 |
| Vic-Dupont, V | 1 |
| Guyochin, A | 1 |
| Bruniaux, J | 1 |
| Tremolières, F | 1 |
| Manuel, C | 1 |
| Gibert, C | 1 |
| O'Neill, JP | 1 |
| Niall, JF | 1 |
| O'Sullivan, EF | 1 |
| Fraser-Moodie, A | 1 |
| Deveridge, RJ | 1 |
| Altemeier, WA | 1 |
| Fullen, WD | 1 |
| Aufranc, OE | 1 |
| Jones, WN | 1 |
| Bierbaum, BE | 1 |
| Rutherford, RB | 1 |
| Evans, JR | 1 |
| Progrebniak, A | 1 |
| Hardaway, RM | 1 |
3 reviews available for penicillin g and Gas Gangrene
| Article | Year |
|---|---|
[Clostridial gas gangrene].
Topics: Diagnosis, Differential; Gas Gangrene; Humans; Penicillin G; Penicillins | 1999 |
Soft tissue infections.
Topics: Anti-Bacterial Agents; Bacterial Infections; Gangrene; Gas Gangrene; Humans; Penicillin G; Tetanus; | 1979 |
Chemoprophylaxis.
Topics: Colon; Drug Combinations; Drug Therapy; Endocarditis, Bacterial; Gas Gangrene; Humans; Infant, Newbo | 1975 |
32 other studies available for penicillin g and Gas Gangrene
| Article | Year |
|---|---|
Gas gangrene. An 11-year review of 73 cases managed with hyperbaric oxygen.
Topics: Accidents, Traffic; Adolescent; Adult; Aged; Amputation, Surgical; Child; Child, Preschool; Debridem | 1984 |
[Cellulitis of the neck due to anaerobic germs: report of 10 cases (author's transl)].
Topics: Anaerobiosis; Cellulitis; Gas Gangrene; Humans; Metronidazole; Neck; Penicillin G | 1982 |
Clostridial gas gangrene associated with congenital generalized lipodystrophy: report of a case.
Topics: Adult; Clostridium; Follow-Up Studies; Gas Gangrene; Humans; Hyperbaric Oxygenation; Lipodystrophy; | 1994 |
Evaluation of therapy with hyperbaric oxygen for experimental infection with Clostridium perfringens.
Topics: Animals; Clindamycin; Clostridium perfringens; Dose-Response Relationship, Immunologic; Female; Gas | 1993 |
[Treatment of gas gangrene].
Topics: Ampicillin; Gas Gangrene; Humans; Hyperbaric Oxygenation; Immunization, Passive; Penicillin G | 1975 |
[Current aspects of gas gangrene, apropos of 47 cases collected over a 3-year period (1974-1976)].
Topics: Adult; Age Factors; Aged; Bacteroides fragilis; Clostridium perfringens; Eubacterium; Female; Gas Ga | 1977 |
High-dose penicillin and gas gangrene.
Topics: Anemia, Hemolytic; Brain Diseases; Gas Gangrene; Humans; Penicillin G | 1976 |
Gangrene infection: new approaches to an old disease.
Topics: Aged; Cephalothin; Clostridium; Female; Fractures, Open; Gas Gangrene; Humans; Hyperbaric Oxygenatio | 1975 |
[Is penicillin G the drug of choice in gas gangrene? Results of a prospective documentation of clinical, microbiological and animal experiment data].
Topics: Adult; Aged; Aged, 80 and over; Animals; Bacteria; Female; Follow-Up Studies; Gas Gangrene; Guinea P | 1992 |
Clostridium perfringens type A. Comparison of in vitro and in vivo activity of twelve antimicrobial drugs.
Topics: Animals; Anti-Bacterial Agents; Cephalosporins; Clostridium perfringens; Fosfomycin; Gas Gangrene; I | 1986 |
Comparison of clindamycin, rifampin, tetracycline, metronidazole, and penicillin for efficacy in prevention of experimental gas gangrene due to Clostridium perfringens.
Topics: Animals; Anti-Bacterial Agents; Clindamycin; Clostridium perfringens; Female; Gas Gangrene; Male; Me | 1987 |
Comparison of single and combination antimicrobial agents for prevention of experimental gas gangrene caused by Clostridium perfringens.
Topics: Animals; Clindamycin; Clostridium perfringens; Drug Therapy, Combination; Female; Gas Gangrene; Male | 1987 |
Chemotherapy of experimental (murine) Clostridium perfringens type A gas gangrene.
Topics: Animals; Ciprofloxacin; Clindamycin; Clostridium perfringens; Disease Models, Animal; Gas Gangrene; | 1988 |
Spontaneous clostridial myonecrosis.
Topics: Aged; Gas Gangrene; Humans; Hyperbaric Oxygenation; Insulin; Isotonic Solutions; Male; Penicillin G | 1985 |
Sequestration of the total bladder mucosa caused by clostridial infection.
Topics: Aged; Clostridium Infections; Clostridium perfringens; Colistin; Cystitis; Cystoscopy; Female; gamma | 1973 |
[A contribution on the active and passive vaccination against Clostridium novyi and Clostridium tetani].
Topics: Animals; Clostridium; Clostridium Infections; Clostridium tetani; Gas Gangrene; Guinea Pigs; Immune | 1967 |
[Experimental studies on animals on the use of pyrrolidino-methyl-tetracycline and penicillin G on the prophylaxis and therapy of gas gangrene].
Topics: Animals; Clostridium; Clostridium Infections; Clostridium perfringens; Gas Gangrene; Guinea Pigs; Mi | 1966 |
[Studies on the antibacterial effect of newer antibiotics on Welch-Fraenkel gas gangrene bacilli (Cl. perfringens)].
Topics: Anti-Bacterial Agents; Cephaloridine; Cephalothin; Clostridium perfringens; Drug Hypersensitivity; G | 1968 |
Activity of metronidazole against experimental tetanus and gas gangrene.
Topics: Animals; Clostridium; Clostridium perfringens; Clostridium tetani; Gas Gangrene; Metronidazole; Mice | 1968 |
[Effectiveness of cephalosporins in experimental anaerobic gas infection].
Topics: Administration, Oral; Animals; Cephalexin; Cephaloridine; Cephalosporins; Cephalothin; Clostridium; | 1974 |
[Gas gangrene. Apropos of 32 cases].
Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; Child; Drainage; Gas Gangrene; Humans; Hyperbaric Ox | 1974 |
Severe postabortal Clostridium welchii infection: trends in management.
Topics: Abortion, Septic; Acute Kidney Injury; Adult; Curettage; Disseminated Intravascular Coagulation; Exc | 1972 |
An unusual presentation of gas gangrene.
Topics: Adult; Ampicillin; Colectomy; Diverticulitis, Colonic; Escherichia coli; Gas Gangrene; Humans; Hyper | 1973 |
Gas gangrene.
Topics: Antitoxins; Gas Gangrene; Humans; Hyperbaric Oxygenation; Penicillin G; Resuscitation | 1973 |
Prophylaxis and treatment of tetanus and other clostridial wound infections.
Topics: Anti-Bacterial Agents; Clostridium Infections; Gas Gangrene; Humans; Immunity, Active; Immunity, Mat | 1973 |
Gas gangrene in New South Wales.
Topics: Abortion, Septic; Adolescent; Adult; Aged; Amputation, Surgical; Australia; Child; Debridement; Fema | 1973 |
[Experimental antibiotic therapy of rare variants of anaerobic gas infection].
Topics: Animals; Anti-Bacterial Agents; Cephaloridine; Clostridium; Clostridium Infections; Gas Gangrene; In | 1973 |
Prevention and treatment of gas gangrene.
Topics: Amputation, Surgical; Cellulitis; Clostridium; Clostridium Infections; Debridement; Diagnosis, Diffe | 1971 |
[What is your diagnosis?].
Topics: Adult; Amputation, Surgical; Blood Transfusion; Chloramphenicol; Female; Forearm Injuries; Fractures | 1971 |
[On the prevention and therapy of gas gangrene].
Topics: Animals; Antitoxins; Gas Gangrene; Guinea Pigs; Humans; Mice; Military Medicine; Penicillin G; Rolit | 1967 |
Gas gangrene complicating fracture of the tibia.
Topics: Adult; Debridement; Gas Gangrene; Humans; Hyperbaric Oxygenation; Male; Penicillin G; Tibial Fractur | 1969 |
Experimental clostridial wounds in rabbits. I. The effect of debridement delay, tetanus immunization, and topical antibiotics on the mortality from gas gangrene.
Topics: Aerosols; Amputation, Surgical; Animals; Bacitracin; Clostridium; Debridement; Female; Gas Gangrene; | 1966 |