meropenem has been researched along with Gas-Gangrene* in 2 studies
2 other study(ies) available for meropenem and Gas-Gangrene
Article | Year |
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The antibiotic susceptibility pattern of gas gangrene-forming
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amoxicillin-Potassium Clavulanate Combination; Anti-Bacterial Agents; Cefoxitin; Child; Child, Preschool; Clindamycin; Clostridium; Clostridium bifermentans; Clostridium histolyticum; Clostridium perfringens; Clostridium septicum; Clostridium sordellii; Clostridium tertium; Drug Resistance, Bacterial; Female; Gas Gangrene; Humans; Hungary; Imipenem; Infant; Inhibitory Concentration 50; Male; Meropenem; Microbial Sensitivity Tests; Middle Aged; Penicillins; Retrospective Studies; Tigecycline; Young Adult | 2020 |
[Massive intravascular hemolysis secondary to sepsis due to Clostridium perfringens].
Massive hemolysis secondary to sepsis caused by Clostridium perfringens is a rare entity but appears fairly often in the literature. In nearly all published reports, the clinical course is rapid and fatal. We describe the case of a 75-year-old woman with diabetes who was admitted with symptoms consistent with acute cholecystitis. Deteriorating hemodynamics and laboratory findings were consistent with intravascular hemolysis, coagulation disorder, and renal failure. Gram-positive bacilli of the Clostridium species were detected in blood along with worsening indicators of hemolysis. In spite of antibiotic and surgical treatment, hemodynamic support and infusion of blood products, the patient continued to decline and died in the postoperative recovery unit 14 hours after admission. Mortality ranges from 70% to 100% in sepsis due to Clostridium perfringens, and risk of death is greater if massive hemolysis is present, as in the case we report. Only a high degree of clinical suspicion leading to early diagnosis and treatment can improve the prognosis. This bacterium should therefore be considered whenever severe sepsis and hemolysis coincide. Topics: Acute Kidney Injury; Aged; Anemia, Hemolytic; Anti-Bacterial Agents; Bacteremia; Blood Component Transfusion; Cholecystectomy; Cholecystitis; Clindamycin; Clostridium perfringens; Combined Modality Therapy; Delayed Diagnosis; Diabetes Complications; Emergencies; Fatal Outcome; Female; Gas Gangrene; Hemofiltration; Humans; Meropenem; Norepinephrine; Postoperative Complications; Shock, Septic; Thienamycins | 2010 |