Page last updated: 2024-10-23

azathioprine and Gas Gangrene

azathioprine has been researched along with Gas Gangrene in 1 studies

Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.

Gas Gangrene: A severe condition resulting from bacteria invading healthy muscle from adjacent traumatized muscle or soft tissue. The infection originates in a wound contaminated with bacteria of the genus CLOSTRIDIUM. C. perfringens accounts for the majority of cases (over eighty percent), while C. noyvi, C. septicum, and C. histolyticum cause most of the other cases.

Research Excerpts

ExcerptRelevanceReference
" We describe the case of a young patient with ulcerative colitis, homozygous for TPMT*3A alleles, who suffered fatal azathioprine-induced myelotoxicity after standard dosing with azathioprine."1.35Fatal myelotoxicity after azathioprine treatment. ( Bortlík, M; Chalupná, P; Krska, Z; Lukás, M; Novotný, A; Slanar, O, 2008)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Slanar, O1
Chalupná, P1
Novotný, A1
Bortlík, M1
Krska, Z1
Lukás, M1

Other Studies

1 other study available for azathioprine and Gas Gangrene

ArticleYear
Fatal myelotoxicity after azathioprine treatment.
    Nucleosides, nucleotides & nucleic acids, 2008, Volume: 27, Issue:6

    Topics: Adult; Azathioprine; Bone Marrow; Colitis, Ulcerative; Drug-Related Side Effects and Adverse Reactio

2008