Conditions > Keratitis, Acanthamoeba
Page last updated: 2024-09-28

Keratitis, Acanthamoeba

Synonyms(1)

Synonym
Keratitis, Acanthamoeba

Research Excerpts

Overview

ExcerptReference
"Acanthamoeba keratitis is an unusual complication of wearing soft contact lenses: a case was diagnosed by culturing corneal scrapings."( Anderson, D; Soo, SS; Towler, H, 1991)
"Acanthamoeba keratitis is an uncommon but potentially devastating complication of contact lens wear."( Fook, TC; Ghosh, M; Hunter, WS; Rabinovitch, J, 1990)
"Acanthamoeba keratitis is an uncommon but devastating complication of contact lens wear causing significant ocular morbidity."( Crawford, GJ; McGhee, CN; Tay-Kearney, ML; Trown, K, 1993)
"Acanthamoeba keratitis is a sight-threatening corneal infection."( Cao, Z; Panjwani, N; Yang, Z, 1997)
"Acanthamoeba keratitis is a chronic inflammatory disease of the cornea which is highly resistant to many antimicrobial agents."( Alizadeh, H; Huang, J; Leher, H; Niederkorn, JY; Silvany, R, 1998)
"Acanthamoeba keratitis is a vision-threatening corneal infection."( Cao, Z; Jefferson, DM; Panjwani, N, 1998)
"Acanthamoeba keratitis is an uncommon corneal infection that can run a protracted course with, at times, serious visual results."( Cursons, R; Gray, TB; Murdoch, D; Parr, D, 1998)
"Acanthamoeba keratitis is a severe ocular infection secondary to accidental macro- or microscopic trauma of the cornea."( Bruno, A; Cevini, C; Gatti, S; Penso, G; Rama, P; Scaglia, M, 1998)
"Acanthamoeba keratitis is a potential threat, with 85% of the cases being reported in contact lens wearers."( Buck, SL; Rosenthal, RA; Schlech, BA, 2000)
"Acanthamoeba keratitis is a potentially devastating infection of the cornea caused by the free-living amoebae, Acanthamoeba species."( Parija, SC; Prakash, MR; Rao, VA; Vellaniparambil, RJ, 2001)
"Acanthamoeba keratitis is a corneal disease associated predominantly with contact lens wear."( Aspöck, H; Duchêne, M; Eibl, H; Walochnik, J, 2003)
"The pathogenesis of Acanthamoeba keratitis is a complex, sequential process."( Alizadeh, H; Hurt, M; Neelam, S; Niederkorn, JY, 2005)
"Acanthamoeba keratitis is an emerging complication of orthokeratology in young myopes."( Wilhelmus, KR, 2005)
"Acanthamoeba keratitis is a rare but severe corneal infection which, despite improvements in diagnosis and treatment, still culminates in prolonged morbidity and significant loss of visual acuity."( Ayadi, A; Ben Salah, S; Ben Zina, Z; Cheikrouhou, F; Colin, J; Feki, J; Makni, F; Mlik, M, 2007)
"Acanthamoeba keratitis is a painful and progressive sight-threatening infection."( Alsam, S; Dudley, R; Jeong, SR; Khan, NA, 2008)
"Bilateral Acanthamoeba keratitis is an infectious complication of contact lens wear."( Hamill, MB; Jones, DB; Matoba, AY; Pflugfelder, SC; Weikert, MP; Wilhelmus, KR, 2008)
"Acanthamoeba keratitis is a painful corneal infection and difficult to treat because no sufficiently efficient drug has yet been available."( Obwaller, A; Polat, ZA; Vural, A; Walochnik, J, 2012)
"Acanthamoeba keratitis is a rare but serious corneal disease, often observed in contact lens wearers."( Capriglione, P; Cennamo, G; Cerulli, L; Del Prete, S; Di Cave, D; Pesce, G; Rusciano, G; Sasso, A, 2013)
"Acanthamoeba keratitis is a debilitating eye disease that requires effective topical drug therapy."( Abdel Aziz, S; Kowalski, RP; Nau, AC; Raju, LV; Romanowski, EG; Shanks, RM, 2013)
"Acanthamoeba keratitis is a painful and progressive infection of the cornea that can result in loss of vision."( Ahmad, K; Chaudhry, T; Khan, NA; Lakhundi, S; Siddiqui, R, 2014)
"Acanthamoeba keratitis is difficult to treat because Acanthamoeba cysts are resistant to the majority of antimicrobial agents."( Huang, CF; Lin, CY; Lin, SC; Shen, LJ; Wang, HJ; Wu, FL, 2015)
"Acanthamoeba keratitis is a rare but serious disease and is particularly difficult to treat when the diagnosis is delayed, partly because of the limitations of current therapies."( Abou-Bacar, A; Bourcier, T; Candolfi, E; Letsch, J; Sauer, A, 2015)
"Acanthamoeba keratitis is rare, but difficult to treat."( Hager, T; Hasenfus, A; Seitz, B; Stachon, T; Szentmáry, N, 2016)
"Acanthamoeba keratitis is a serious infection with blinding consequences and often associated with contact lens wear."( Anwar, A; Aqeel, Y; Khan, NA; Shah, MR; Siddiqui, R, 2015)
"Acanthamoeba keratitis is commonly encountered by contact lens wearers."( Kong, HH; Lee, S; Moon, EK; Quan, FS, 2018)
"Acanthamoeba keratitis is a vision-threatening corneal infection with currently no available fully effective treatment."( Chomicz, L; Grobelny, J; Grodzik, M; Hendiger, EB; Lorenzo-Morales, J; Padzik, M; Szmidt, M, 2018)
"Acanthamoeba keratitis is an ophthalmic disease with no specific treatment that specially affects contact lens users."( Brazil, NT; Maschio, VJ; Rott, MB; Schuh, RS; Teixeira, HF; Zorzi, GK, 2019)
"Acanthamoeba keratitis is a rare, vision-threatening disease."( Dewan, N; Holland, SP; Iovieno, A; Ming, W; Yeung, SN, 2019)
"Diagnosis of acanthamoeba keratitis is often a clinical challenge."( Ardjomand, N; Daas, L; Dirisamer, M; Frings, A; Pascha, J; Walochnik, J; Wissiak, E, 2020)
"Acanthamoeba keratitis is caused by a protozoal infection of the cornea, with 80% of cases involving the improper use of contact lenses."( Heard, CM; Hewitt, M; Kelly, SL; Lewis, PN; Morgan, SR; Morrison, PWJ; Moseley, R; Moses, RL; Parker, JE; Pilia, N; Quantock, AJ; Whitaker, D, 2020)
"Acanthamoeba keratitis is a serious infection of the eye that can result in permanent visual impairment or blindness, caused by free-living amoebae of the genus Acanthamoeba."( Ghahvehchian, H; Latifi, A; Mohammadi, SS; Momenaei, B; Soleimani, M; Tayebi, F, 2021)
"Acanthamoeba keratitis is a sight-endangering eye infection, and causative organism Acanthamoeba presents a significant concern to public health, given escalation of contact lens wearers."( Anuar, TS; Khan, NA; Maciver, SK; Mungroo, MR; Siddiqui, R; Tong, T, 2021)
"Acanthamoeba keratitis is a painful, sight-threatening infection."( Akbar, N; Ibrahim, T; Khamis, M; Khan, NA; Siddiqui, R, 2022)
"Outcomes of Acanthamoeba keratitis are often worse in India than in the United States."( Cevallos, V; Elakkiya, S; Kamal, FS; Keenan, JD; Lietman, TM; Prajna, L; Prajna, NV; Rajaraman, R; Richardson, QR; Seitzman, GD; Talbott, M, 2023)

Context

ExcerptReference
"The treatment of Acanthamoeba keratitis has been increasingly successful as diagnoses are made earlier."( Bacon, AS; Dart, JK; Ficker, LA; Matheson, MM; Wright, P, 1993)
"Acanthamoeba keratitis has become an important cause of severe ocular inflammation and visual loss in the past two decades."( Cheng, CL; Lim, L; Ling, ML, 2000)
"The diagnosis of acanthamoeba keratitis has increased since 1985 due to the massive use of contact lenses and a better knowledge of the disease by ophthalmologists."( Donoso, R; López, M; Mura, JJ, 2002)
"The treatment of Acanthamoeba keratitis has now been possible since the first successful therapy developed in the mid 1980s with a combination of propamidine 0."( Seal, D, 2003)
"The occurrence of Acanthamoeba keratitis has been rising since 1990 in correlation to the growing number of contact lens wearers."( Aspöck, H; Duchêne, M; Eibl, H; Walochnik, J, 2003)
"Interestingly, Acanthamoeba keratitis has remained significant, despite our advances in antimicrobial chemotherapy and supportive care."( Khan, NA; Lorenzo-Morales, J; Walochnik, J, 2015)

Treatment

ExcerptReference
"Intense treatment of Acanthamoeba keratitis with these medications has not been reported before for as long as 11 days."( John, T; Lin, J; Sahm, DF, 1990)
"A retrospective review of all patients treated for Acanthamoeba keratitis between September 1992 and February 1995 was carried out."( Allan, BD; Dart, JK; Duguid, IG; Ficker, L; Matheson, M; Morlet, N; Tuft, S, 1997)
"Following successful treatment of Acanthamoeba keratitis, the LASIK procedure can be performed on previously infected cornea with successful results."( Lim, L; Wei, RH, 2004)
"For example, current treatment against Acanthamoeba keratitis requires early diagnosis followed by hourly topical application of a mixture of drugs that can last up to a year."( Alsam, S; Dudley, R; Khan, NA, 2007)
"CXL was effective for treating Acanthamoeba keratitis in an orthokeratology patient to eliminate active and cystic forms of the microorganism."( Arance-Gil, Á; González-Méijome, JM; Gutiérrez-Ortega, ÁR; Lopes-Ferreira, D; Nieto-Bona, A; Villa-Collar, C, 2014)
"Efficient treatments against Acanthamoeba Keratitis (AK), remains until the moment, as an issue to be solved due to the existence of a cyst stage which is highly resistant to most chemical and physical agents."( Chiboub, O; De Agustino Rodríguez, J; López-Arencibia, A; Lorenzo-Morales, J; Piñero, JE; Reyes-Batlle, M; Rocha-Cabrera, P; Sifaoui, I; Valladares, B; Wagner, C, 2017)

Research

Studies (414)

TimeframeStudies, This Condition (%)All Conditions %
pre-19903 (0.72)23.3326
1990's79 (19.08)12.5806
2000's119 (28.74)18.1394
2010's152 (36.71)28.8240
2020's61 (14.73)9.53
DrugIndicatedRelationship StrengthStudiesTrials
carbamates0low10
coumarin0low10
salicylic acid0low10
lactic acid0low10
dimethyl sulfoxide0low10
methanol0low10
inositol0low10
phosphorylcholine0low160
propylene glycol0low20
taurine0low20
acetaminophen0low10
alexidine0low10
amlodipine0low10
benzethonium0low10
cetylpyridinium0low10
chloroquine0low30
ciprofloxacin0low20
clotrimazole0low40
cyclopentolate0low10
dichlobanil0low30
diclofenac0low30
dicyclomine0low10
fluconazole0low60
fluorouracil0low10
gentamicin0low20
glimepiride0low10
miltefosine0low170
indomethacin0low10
2-propanol0low30
ketoconazole0low80
metformin0low10
metronidazole0low80
miconazole0low80
ofloxacin0low50
benoxinate0low10
pentamidine0low80
phenylmethylsulfonyl fluoride0low10
pirenoxine0low10
potassium iodide0low10
procaine0low10
proxymetacaine0low10
gatifloxacin0low10
tropicamide0low10
prednisolone0low40
prednisolone acetate0low10
isoflurophate0low10
biguanides0medium1073
serine0low10
chloramphenicol0low20
cephalothin0low10
galactose0low10
carbostyril0low10
phenylephrine0low10
edetic acid0low10
lactose0low10
phencyclidine0low30
peracetic acid0low10
propoxycaine0low10
xanthenes0low20
2-methylpentane0low10
n-hexane0low10
framycetin0medium231
perylene0low10
thiazoles0low20
betamethasone0low10
fluorometholone0low10
fusarium0low110
hematoxylin0low10
eosine yellowish-(ys)0low10
gentian violet0low10
resazurin0low20
toyocamycin0low10
dibrompropamidine0low50
erythromycin0low10
potassium hydroxide0low20
sodium hydroxide0low10
vancomycin0low20
amiloride0low10
fluorescein0low20
mannose0low70
vantocil0medium983
terbutylazine0low10
platinum0low10
silver0low70
titanium0low10
gold0low50
chlorine0low10
clodronic acid0low20
titanium dioxide0low10
cefazolin0low10
timolol0low20
tobramycin0low30
ticarcillin0low10
nitazoxanide0low10
octenidine0low10
itraconazole0low50
adenosine0low10
vanadates0low10
acridine orange0low10
ursolic acid0low10
propamidine0low230
thiazolyl blue0low10
hexamidine0low180
repaglinide0low10
propamidine isethionate0medium441
triazoles0low120
artemether0low10
voriconazole0medium281
prednisolone phosphate0low10
pacein0low10
isoxaben0low10
1,2-distearoylphosphatidylethanolamine0low10
n-chlorotaurine0low10
levofloxacin0low50
moxifloxacin0low50
paromomycin0low10
myristamidopropyl dimethylamine0low30
atropine0low30
organophosphonates0low20
povidone-iodine0low50
epiglucan0low10
cellulase0low10
meropenem0low10
netilmicin0low10
acriflavine0low10
loteprednol etabonate0low10
resveratrol0low10
oleic acid0low10
zithromax0low20
y 276320low10
mannobiose0low10
posaconazole0low10
l 743,8720low20
micafungin0low10
riboflavin0low90
bromochloroacetic acid0low10
hypocrellin b0low10
3-(4,5-dimethylthiazol-2-yl)-5-(3-carboxymethoxyphenyl)-2-(4-sulfophenyl)-2h-tetrazolium0low10
arachidonyltrifluoromethane0low10
genistein0low10
amphotericin b0low50
baicalein0low10
mangostin0low10
pitavastatin0low10
5,7-dihydroxy-6-methoxy-2-phenylchromen-4-one0low10
lead0low10
arsenic0low10
c.i. fluorescent brightening agent 280low30
1,2-dioleoyloxy-3-(trimethylammonium)propane0low10
dioleoyl phosphatidylethanolamine0low10
isavuconazole0low10
vildagliptin0low10
chlorhexidine0medium873
mocetinostat0low10
brimonidine tartrate0low10
brimonidine tartrate, timolol maleate drug combination0low10
gramicidin a0low10
tannins0low30
cellulose0low20
thimerosal0low10
sodium salicylate0low30
chitosan0low10
4-hydroxymercuribenzoate0low20
arabinogalactan0low10
mannans0low10
piperidines0low10
interleukin-80low30
methylcellulose0low10
warfarin0low10
clay0low20
agar0low10
caseins0low10
cytochalasin d0low10
lactoferrin0low20
muramidase0low10
exudates0low40
acyclovir0low10
guanosine0low10
valacyclovir0low10
trypan blue0low10
direct black 30low10
eye0low60
concanavalin a0low10

Protein Targets (1,347)

ProteinPotency MeasurementsInhibition MeasurementsActivation MeasurementsDrugs
retinoic acid nuclear receptor alpha variant 1330033
retinoid X nuclear receptor alpha280028
estrogen-related nuclear receptor alpha330033
pregnane X nuclear receptor310031
hypoxia-inducible factor 1 alpha subunit170017
RAR-related orphan receptor gamma280028
GLI family zinc finger 3320032
AR protein390039
aldehyde dehydrogenase 1 family, member A1230023
estrogen nuclear receptor alpha480048
peroxisome proliferator-activated receptor delta200020
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a210021
activating transcription factor 6150015
v-jun sarcoma virus 17 oncogene homolog (avian)150015
Histone H2A.x170017
thyroid hormone receptor beta isoform a130013
heat shock protein beta-1140014
nuclear factor erythroid 2-related factor 2 isoform 1340034
lamin isoform A-delta10290029
Voltage-dependent calcium channel gamma-2 subunit190019
Glutamate receptor 2200121
Trypsin-10404
Trypsin-20303
Cyclic AMP-responsive element-binding protein 10002
Trypsin-30303
Receptor-type tyrosine-protein kinase FLT30202
ATAD5 protein, partial9009
GLS protein120012
Microtubule-associated protein tau170018
Smad38008
thyroid stimulating hormone receptor170017
nuclear receptor subfamily 1, group I, member 3250025
progesterone receptor220022
EWS/FLI fusion protein270027
peroxisome proliferator activated receptor gamma220022
aryl hydrocarbon receptor190019
chromobox protein homolog 1160016
thyroid hormone receptor beta isoform 2260026
peripheral myelin protein 22160016
cytochrome P450 3A4 isoform 1190019
Gamma-aminobutyric acid receptor subunit pi192123
ATP-binding cassette sub-family C member 3032032
Multidrug resistance-associated protein 4032033
Solute carrier family 22 member 60506
Carbonic anhydrase 120506
UDP-glucuronosyltransferase 1A90103
Bile salt export pump0505
Bile salt export pump047047
Cytochrome P450 2B10001
Cytochrome P450 1A10001
Carbonic anhydrase 10809
Carbonic anhydrase 209010
Myoglobin0101
Cytochrome P450 1A10214
Cytochrome P450 1A20607
Prostaglandin G/H synthase 10719
Carbonic anhydrase 30505
Cytochrome P450 3A4023026
Cytochrome P450 2D60909
Cytochrome P450 2C9 018221
Polyunsaturated fatty acid lipoxygenase ALOX150303
Gamma-aminobutyric acid receptor subunit beta-1192123
Sulfotransferase 1A1 0001
Gamma-aminobutyric acid receptor subunit delta192123
Gamma-aminobutyric acid receptor subunit gamma-2192123
UDP-glucuronosyltransferase 1-60304
Gamma-aminobutyric acid receptor subunit alpha-5192123
Gamma-aminobutyric acid receptor subunit alpha-3192123
Arachidonate 5-lipoxygenase-activating protein0101
UDP-glucuronosyltransferase 1A1 0506
Carbonic anhydrase 40606
Prostaglandin G/H synthase 10707
Carbonic anhydrase 60505
Gamma-aminobutyric acid receptor subunit gamma-1192123
Gamma-aminobutyric acid receptor subunit alpha-2192123
Gamma-aminobutyric acid receptor subunit alpha-4192123
Gamma-aminobutyric acid receptor subunit gamma-3192123
Gamma-aminobutyric acid receptor subunit alpha-6192123
Carbonic anhydrase 5A, mitochondrial0606
Prostaglandin G/H synthase 2010112
Carbonic anhydrase 70505
Nuclear receptor ROR-gamma111012
Cytochrome P450 2J20505
Gamma-aminobutyric acid receptor subunit alpha-1192123
Gamma-aminobutyric acid receptor subunit beta-3192123
Gamma-aminobutyric acid receptor subunit beta-2192123
Carbonic anhydrase 90708
GABA theta subunit192123
Canalicular multispecific organic anion transporter 1030030
Carbonic anhydrase 150404
Carbonic anhydrase 130303
Gamma-aminobutyric acid receptor subunit epsilon192123
Carbonic anhydrase 140505
Carbonic anhydrase 5B, mitochondrial0505
toxin B0001
Telomerase reverse transcriptase0101
Amyloid-beta precursor protein1517
Reverse transcriptase/RNaseH 0102
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE170017
acetylcholinesterase140014
SMAD family member 2150015
Fumarate hydratase6006
SMAD family member 3150015
TDP1 protein390039
caspase 7, apoptosis-related cysteine protease6006
estrogen receptor 2 (ER beta)190019
cytochrome P450 family 3 subfamily A polypeptide 4330033
glucocorticoid receptor [Homo sapiens]360036
farnesoid X nuclear receptor220022
cytochrome P450 2D6230023
polyprotein6006
67.9K protein130013
vitamin D (1,25- dihydroxyvitamin D3) receptor190019
caspase-36006
thyroid stimulating hormone receptor140014
thyrotropin-releasing hormone receptor6006
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a150015
potassium voltage-gated channel subfamily H member 2 isoform d7007
Interferon beta330033
Cellular tumor antigen p53320032
Spike glycoprotein191121
ATPase family AAA domain-containing protein 5110011
Ataxin-2130013
Chain E, Purine nucleoside phosphorylase0101
Chain A, HADH2 protein170017
Chain B, HADH2 protein170017
Chain A, ATP-DEPENDENT DNA HELICASE Q18008
Chain A, Ferritin light chain110011
Thymidine kinase 0101
thioredoxin reductase200020
phosphopantetheinyl transferase140014
arylsulfatase A100010
euchromatic histone-lysine N-methyltransferase 2240024
Bloom syndrome protein isoform 1120012
hemoglobin subunit beta3003
atrial natriuretic peptide receptor 1 precursor2002
ubiquitin carboxyl-terminal hydrolase 2 isoform a5005
Solute carrier family 22 member 1 08010
Purine nucleoside phosphorylase0203
Thymidine kinase, cytosolic0001
POU domain, class 2, transcription factor 20001
Disintegrin and metalloproteinase domain-containing protein 175005
Purine nucleoside phosphorylase0011
Solute carrier family 22 member 60506
Thymidine kinase 0101
Solute carrier family 22 member 80406
Thymidine kinase0101
Chain A, Membrane lipoprotein tmpC0022
Chain A, Membrane lipoprotein tmpC0022
Chain A, Membrane lipoprotein tmpC0022
Chain A, Structure of PAE2307 in complex with adenosine0011
Chain B, Structure of PAE2307 in complex with adenosine0011
Chain A, ADENOSINE RECEPTOR A2A0101
Chain A, ADENOSINE RECEPTOR A2A0101
Chain A, tRNA (guanine-N(1)-)-methyltransferase0011
Chain A, Uncharacterized protein MJ08830011
signal transducer and activator of transcription 6, interleukin-4 induced1001
regulator of G-protein signaling 4100010
NPYLR7B0033
IDH1150015
glycogen synthase kinase-3 beta isoform 10022
mitogen-activated protein kinase 1130013
flap endonuclease 1140014
nuclear receptor ROR-gamma isoform 1200020
survival motor neuron protein isoform d110011
high affinity choline transporter 1 isoform a0101
Sodium/nucleoside cotransporter 10202
Calcium dependent protein kinase0101
Mitogen-activated protein kinase kinase kinase 70011
Sodium/nucleoside cotransporter 20202
Rap guanine nucleotide exchange factor 37007
Epidermal growth factor receptor0808
Phosphoglycerate kinase 1 0101
Adenosine deaminase0001
Avidin0011
Adenosine deaminase0001
Glyceraldehyde-3-phosphate dehydrogenase0404
Receptor tyrosine-protein kinase erbB-20303
Insulin receptor0001
Phosphoglycerate kinase 20101
Heat shock protein HSP 90-alpha0112
Platelet-derived growth factor receptor beta0001
Adenosine receptor A308211
Heat shock 70 kDa protein 1A 0101
Heat shock cognate 71 kDa protein0022
Fibroblast growth factor receptor 10001
Inosine-5'-monophosphate dehydrogenase 20101
Endoplasmin0112
Inosine-5'-monophosphate dehydrogenase 1 0101
Fibroblast growth factor receptor 20001
Fibroblast growth factor receptor 40001
Fibroblast growth factor receptor 30001
Streptavidin0011
Adenosylhomocysteinase0103
Adenosine receptor A10314
Adenosine receptor A30202
Adenosine receptor A2a010213
Adenosine receptor A2b0012
Adenosine receptor A2b0213
Adenylate kinase 2, mitochondrial0101
Adenosine receptor A108211
Adenosine receptor A2a0415
Adenylate kinase isoenzyme 1 0101
Phosphatidylinositol 4-kinase alpha0203
Adenosine receptor A10011
Adenosine kinase0102
Adenosine deaminase 0001
Equilibrative nucleoside transporter 20202
Phosphatidylinositol 4-kinase type 2-beta0203
Histone-lysine N-methyltransferase, H3 lysine-79 specific0202
Equilibrative nucleoside transporter 10202
Phosphatidylinositol 4-kinase type 2-alpha0203
Solute carrier family 28 member 30202
Adenosine kinase0102
Phosphatidylinositol 4-kinase beta0203
5-methylthioadenosine/S-adenosylhomocysteine deaminase0001
Adenosine transporter 10001
Chain U, UROKINASE-TYPE PLASMINOGEN ACTIVATOR0101
Chain A, UROKINASE-TYPE PLASMINOGEN ACTIVATOR0101
Chain A, UROKINASE-TYPE PLASMINOGEN ACTIVATOR0101
Chain A, 2-oxoglutarate Oxygenase160016
acid sphingomyelinase5005
glucocerebrosidase100010
alpha-galactosidase2002
cytochrome P450 2D6 isoform 1150015
lysosomal alpha-glucosidase preproprotein4004
cytochrome P450 2C19 precursor100010
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1140014
huntingtin isoform 29009
geminin290029
Membrane primary amine oxidase 0101
Prothrombin0303
Coagulation factor X0202
Plasminogen0202
Urokinase-type plasminogen activator0505
Tissue-type plasminogen activator0202
Cationic trypsin0101
Coagulation factor XI0101
Plasma kallikrein0101
Vitamin K-dependent protein C0101
Urokinase-type plasminogen activator0202
Sodium/hydrogen exchanger 10101
Amine oxidase [flavin-containing] A0606
Sodium/hydrogen exchanger 10202
Sodium/hydrogen exchanger 30202
Amiloride-sensitive sodium channel subunit alpha0101
5-hydroxytryptamine receptor 70303
Sodium/hydrogen exchanger 20202
Acid-sensing ion channel 10101
Potassium voltage-gated channel subfamily H member 2023025
Sodium channel protein type 5 subunit alpha0202
Sodium/hydrogen exchanger 50202
Solute carrier family 22 member 10102
Solute carrier family 22 member 20101
Acid-sensing ion channel 30101
Sodium/hydrogen exchanger0101
G240024
NEDD8-activating enzyme E1 regulatory subunit isoform a0101
NEDD8-conjugating enzyme Ubc120101
histone acetyltransferase KAT2A isoform 1180018
Voltage-dependent L-type calcium channel subunit alpha-1C0303
Potassium channel subfamily K member 20112
HLA class I histocompatibility antigen, B alpha chain 240024
ATP-dependent translocase ABCB1013116
Alpha-2A adrenergic receptor015116
Alpha-2C adrenergic receptor0617
Alpha-2B adrenergic receptor0303
Voltage-dependent L-type calcium channel subunit alpha-1C0303
Alpha-2C adrenergic receptor0303
Alpha-2A adrenergic receptor0303
Alpha-1D adrenergic receptor0909
Alpha-1A adrenergic receptor0213
Alpha-1B adrenergic receptor0213
5-hydroxytryptamine receptor 60808
Sodium-dependent dopamine transporter 014014
Voltage-dependent L-type calcium channel subunit alpha-1C0505
Potassium channel subfamily K member 2 0101
Inositol hexakisphosphate kinase 1240024
cytochrome P450 2C9, partial240024
Chain A, Cruzipain110011
interleukin 86006
tumor necrosis factor3003
vitamin D3 receptor isoform VDRA140014
Cytochrome P450 2C19010010
Aurora kinase B0404
Broad substrate specificity ATP-binding cassette transporter ABCG20505
Cytosolic phospholipase A2 0101
DNA polymerase kappa isoform 1180018
Fatty-acid amide hydrolase 10303
Polyunsaturated fatty acid lipoxygenase ALOX15B132015
Neuronal acetylcholine receptor subunit alpha-41304
Cytosolic phospholipase A2 beta0101
Neuronal acetylcholine receptor subunit beta-21304
Glutamate receptor 11012
Glutamate receptor 31012
Glutamate receptor 41012
Cannabinoid receptor 10011
Cytosolic phospholipase A20101
Histamine H2 receptor180019
Fatty-acid amide hydrolase 11304
Platelet-activating factor acetylhydrolase0101
Monoglyceride lipase0101
Cytosolic phospholipase A2 gamma0202
cystic fibrosis transmembrane conductance regulator0101
DNA polymerase beta5005
short transient receptor potential channel 6 isoform 10011
5-hydroxytryptamine receptor 4012012
Muscarinic acetylcholine receptor M2017121
Muscarinic acetylcholine receptor M4015118
Muscarinic acetylcholine receptor M10226
Muscarinic acetylcholine receptor M30226
Muscarinic acetylcholine receptor M40226
Muscarinic acetylcholine receptor M50226
Muscarinic acetylcholine receptor M5011114
Muscarinic acetylcholine receptor M20227
Muscarinic acetylcholine receptor M1013117
Muscarinic acetylcholine receptor M10013
Muscarinic acetylcholine receptor M3013116
5-hydroxytryptamine receptor 2C012012
Muscarinic acetylcholine receptor M40113
Muscarinic acetylcholine receptor0112
Chain A, Putative fructose-1,6-bisphosphate aldolase120012
Chain A, JmjC domain-containing histone demethylation protein 3A100010
Chain A, RNA-directed RNA polymerase NS50202
endonuclease IV6006
BRCA13003
15-lipoxygenase, partial100010
WRN3003
PPM1D protein130013
hypothetical protein, conserved5005
Lysine-specific demethylase 4E0202
Replicase polyprotein 1ab0314
cellular tumor antigen p53 isoform a110011
polyunsaturated fatty acid lipoxygenase ALOX124004
cytochrome P450 2C9 precursor110011
peptidyl-prolyl cis-trans isomerase NIMA-interacting 14004
DNA polymerase eta isoform 13003
DNA polymerase iota isoform a (long)120012
urokinase-type plasminogen activator precursor9009
plasminogen precursor9009
urokinase plasminogen activator surface receptor precursor9009
dual specificity tyrosine-phosphorylation-regulated kinase 1A0001
lethal(3)malignant brain tumor-like protein 1 isoform I4004
lethal factor (plasmid)120012
Gamma-aminobutyric acid receptor subunit pi0101
Gamma-aminobutyric acid receptor subunit delta0101
Lysine-specific histone demethylase 1A0303
Glucocorticoid receptor09117
Integrin beta-3100010
Progesterone receptor0304
Cyclin-dependent kinase 10303
Tyrosine-protein kinase Yes0101
Seed linoleate 13S-lipoxygenase-10202
Integrin alpha-IIb100010
Fructose-1,6-bisphosphatase 10101
Polyunsaturated fatty acid 5-lipoxygenase0303
Replicase polyprotein 1ab0426
Replicase polyprotein 1ab0437
Lysosomal alpha-glucosidase0303
Androgen receptor0316
Polyunsaturated fatty acid 5-lipoxygenase0304
Sucrase-isomaltase, intestinal0303
G2/mitotic-specific cyclin-B10202
Gamma-aminobutyric acid receptor subunit alpha-10101
Urease subunit alpha0101
Cytochrome P450 11B1, mitochondrial0101
Polyunsaturated fatty acid lipoxygenase ALOX150303
Polyunsaturated fatty acid lipoxygenase ALOX120303
Gamma-aminobutyric acid receptor subunit beta-10101
Gamma-aminobutyric acid receptor subunit gamma-20101
Casein kinase II subunit alpha'0101
Sucrase-isomaltase, intestinal0303
Sodium- and chloride-dependent GABA transporter 10303
Dipeptidyl peptidase 40617
Gamma-aminobutyric acid receptor subunit beta-30101
Gamma-aminobutyric acid receptor subunit alpha-50101
Sodium- and chloride-dependent GABA transporter 20303
Sodium- and chloride-dependent GABA transporter 30303
Gamma-aminobutyric acid receptor subunit alpha-30101
5-hydroxytryptamine receptor 70101
Prostaglandin G/H synthase 2 0303
Testosterone 17-beta-dehydrogenase 30202
Alpha-synuclein4206
Linoleate 9S-lipoxygenase-40101
G protein-coupled receptor kinase 60101
1-deoxy-D-xylulose 5-phosphate reductoisomerase0101
Gamma-aminobutyric acid receptor subunit alpha-20101
Gamma-aminobutyric acid receptor subunit beta-20101
Xanthine dehydrogenase/oxidase0202
Sodium- and chloride-dependent betaine transporter0303
Prolyl endopeptidase0202
Gamma-aminobutyric acid receptor subunit alpha-40101
Serine/threonine-protein kinase PLK10101
Death-associated protein kinase 10202
Casein kinase II subunit beta0101
Casein kinase II subunit alpha0101
Urease subunit beta0101
Gamma-aminobutyric acid receptor subunit epsilon0101
4-aminobutyrate aminotransferase, mitochondrial0101
Xanthine dehydrogenase/oxidase0303
Lactoylglutathione lyase0303
Receptor-type tyrosine-protein phosphatase S0101
Gamma-aminobutyric acid receptor subunit alpha-60101
Cytochrome P450 1B10404
Prostaglandin G/H synthase 1 0303
Integrase 0303
Polyunsaturated fatty acid lipoxygenase ALOX15B0101
Gamma-aminobutyric acid receptor subunit gamma-10101
Casein kinase II subunit alpha 30101
Gamma-aminobutyric acid receptor subunit gamma-30101
Serine/threonine-protein kinase PLK30101
G-protein coupled receptor 350112
Serine/threonine-protein kinase PLK20101
Gamma-aminobutyric acid receptor subunit theta0101
Sialidase-20202
ATP-dependent phosphofructokinase9009
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)130013
USP1 protein, partial150015
interferon gamma precursor0002
pregnane X receptor9009
nuclear receptor subfamily 1, group I, member 2100010
nuclear factor erythroid 2-related factor 2 isoform 2120012
galanin receptor type 30101
Glycine receptor subunit alpha-10808
Glycine receptor subunit beta0808
Glycine receptor subunit alpha-20808
Glycine receptor subunit alpha-30808
ORF730011
Chain A, serum paraoxonase0101
Neutrophil cytosol factor 10101
Carbonic anhydrase 130303
Poly [ADP-ribose] polymerase tankyrase-20101
Luciferase160016
apical membrane antigen 1, AMA14004
Solute carrier family 15 member 10405
Solute carrier family 22 member 110202
Solute carrier family 22 member 80202
Chain A, TYROSYL-DNA PHOSPHODIESTERASE120012
Beta-lactamase 0002
Beta-lactamase 0001
Beta-lactamase 0002
Beta-lactamase 0001
Beta-lactamase 0003
Beta-lactamase 0002
Beta-lactamase 0001
Beta-lactamase 0003
Metallo-beta-lactamase type 20013
Metallo-beta-lactamase VIM-11 0002
Metallo-beta-lactamase VIM-20002
Beta-lactamase 0001
Beta-lactamase 0001
Beta-lactamase 0003
Metallo-beta-lactamase0003
Beta-lactamase 0001
DNA (cytosine-5)-methyltransferase 1 isoform b0101
importin subunit beta-1 isoform 14004
serine/threonine-protein kinase PLK16006
snurportin-14004
carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 isoform 10101
Solute carrier family 22 member 80203
Beta-lactamase0001
Beta-lactamase0002
Beta-lactamase SHV-10002
Beta-lactamase SHV-10003
Beta-lactamase OXA-10001
Beta-lactamase0002
Kappa-type opioid receptor0002
Beta-lactamase TEM0103
B2 metallo-beta-lactamase 0002
Beta-lactamase 0001
Beta-lactamase 0001
Beta-lactamase 0001
Solute carrier family 15 member 20101
Metallo-beta-lactamase VIM-130103
Beta-lactamase 0002
Efflux transporter 0001
Beta-lactamase 0001
Metallo-beta-lactamase VIM-20002
Beta-lactamase 0002
Beta-lactamase Toho-10001
Beta-lactamase 0001
Beta-lactamase 0002
Solute carrier family 22 member 70103
Metallo-beta-lactamase0002
Solute carrier family 15 member 20202
Beta-lactamase 0002
Beta-lactamase 0002
Beta-lactamase 0002
Metallo-b-lactamase 0002
Beta-lactamase 0001
Carbapenem-hydrolyzing beta-lactamase KPC0002
Histamine H3 receptor0002
Beta-lactamase class B VIM-2 0013
Beta-lactamase VIM-1 0103
Solute carrier family 22 member 70101
phosphoglycerate kinase2002
streptokinase A precursor0099
Dihydroxyacetone phosphate acyltransferase0001
30S ribosomal protein S60617
30S ribosomal protein S70617
50S ribosomal protein L150617
50S ribosomal protein L100617
50S ribosomal protein L110617
50S ribosomal protein L7/L120617
50S ribosomal protein L190617
50S ribosomal protein L10617
50S ribosomal protein L200617
50S ribosomal protein L270617
50S ribosomal protein L280617
50S ribosomal protein L290617
50S ribosomal protein L310617
50S ribosomal protein L31 type B0617
50S ribosomal protein L320617
50S ribosomal protein L330617
50S ribosomal protein L340617
50S ribosomal protein L350617
50S ribosomal protein L360617
30S ribosomal protein S100617
30S ribosomal protein S110617
30S ribosomal protein S120617
30S ribosomal protein S130617
30S ribosomal protein S160617
30S ribosomal protein S180617
30S ribosomal protein S190617
30S ribosomal protein S200617
30S ribosomal protein S20617
30S ribosomal protein S30617
30S ribosomal protein S40617
30S ribosomal protein S50617
30S ribosomal protein S80617
30S ribosomal protein S90617
50S ribosomal protein L130617
50S ribosomal protein L140617
50S ribosomal protein L160617
50S ribosomal protein L230617
30S ribosomal protein S150617
50S ribosomal protein L170617
50S ribosomal protein L210617
50S ribosomal protein L300617
50S ribosomal protein L60617
30S ribosomal protein S140617
30S ribosomal protein S170617
30S ribosomal protein S10617
50S ribosomal protein L180617
50S ribosomal protein L20617
50S ribosomal protein L30617
50S ribosomal protein L240617
50S ribosomal protein L40617
50S ribosomal protein L220617
50S ribosomal protein L50617
30S ribosomal protein S210617
50S ribosomal protein L250617
50S ribosomal protein L36 20617
Methionine--tRNA ligase, mitochondrial0011
Chain A, BCL-2-RELATED PROTEIN A10033
PAX80001
glp-1 receptor, partial9009
PINK11001
Parkin4004
heat shock protein 900022
calcineurin A1, putative0022
hepatocyte nuclear factor 4-alpha isoform 20101
perilipin-50101
perilipin-10101
transcriptional regulator ERG isoform 35005
ubiquitin-conjugating enzyme E2 N0101
nuclear factor NF-kappa-B p105 subunit isoform 14015
protein AF-9 isoform a0001
melanocortin receptor 40101
CAAX prenyl protease0002
bcl-2-related protein A10101
1-acylglycerol-3-phosphate O-acyltransferase ABHD5 isoform a0101
glycogen synthase kinase-3 alpha0002
hexokinase HKDC10101
DNA repair protein RAD52 homolog isoform a0001
bcl-2-like protein 11 isoform 10033
Synaptojanin-20101
Solute carrier family 22 member 20303
Synaptojanin-10101
Solute carrier family 22 member 30202
Glutathione reductase, mitochondrial0102
72 kDa type IV collagenase0202
Matrix metalloproteinase-90202
Trypanothione reductase0101
TAR DNA-binding protein 439009
Peroxisomal N(1)-acetyl-spermine/spermidine oxidase0101
Multidrug and toxin extrusion protein 20202
Rap guanine nucleotide exchange factor 47007
Multidrug and toxin extrusion protein 10707
Spermine oxidase0101
glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase0202
Spike glycoprotein0112
glucose-6-phosphate 1-dehydrogenase isoform b0202
Transmembrane protease serine 20112
Dihydrofolate reductase 0101
DNA ligase0101
Riboflavin-binding protein0123
Major prion protein0011
Histidine-rich protein PFHRP-II0304
Procathepsin L0213
Replicase polyprotein 1a0112
Replicase polyprotein 1ab0112
Spike glycoprotein0101
Ribosyldihydronicotinamide dehydrogenase [quinone]0314
Alpha-2B adrenergic receptor010010
DNA ligase 10101
Serine/threonine-protein kinase mTOR0101
Nuclear receptor subfamily 4 group A member 20033
Beta-secretase 10202
Calcium-dependent protein kinase 10011
MO15-related protein kinase Pfmrk 0202
DNA ligase A0101
Sigma intracellular receptor 20101
Phosphoethanolamine N-methyltransferase0101
Sigma non-opioid intracellular receptor 10606
Angiotensin-converting enzyme 2 0112
Cysteine proteinase falcipain 2a 0101
Cysteine proteinase falcipain 2a 0101
DNA gyrase subunit B0101
DNA gyrase subunit A0101
DNA gyrase subunit B0204
DNA gyrase subunit A0408
DNA gyrase subunit B0408
DNA topoisomerase 4 subunit A0101
DNA topoisomerase 4 subunit B0103
DNA topoisomerase 4 subunit A0305
DNA topoisomerase 2-alpha0106
DNA gyrase subunit A0204
Multidrug resistance protein MdtK0011
DNA gyrase subunit B0305
DNA gyrase subunit A0507
Enoyl-[acyl-carrier-protein] reductase [NADH]0001
DNA topoisomerase 4 subunit A0101
DNA topoisomerase 4 subunit B0101
Type IV secretion-like conjugative transfer relaxase protein TraI 0101
Stromelysin-10112
Macrophage metalloelastase0101
NFKB1 protein, partial3003
Thrombopoietin4004
isocitrate dehydrogenase 1, partial1001
nonstructural protein 12002
bromodomain adjacent to zinc finger domain 2B5005
pyruvate kinase5005
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)4004
Caspase-73003
beta-2 adrenergic receptor0011
peripheral myelin protein 22 isoform 15005
caspase-33003
ras-related protein Rab-9A6006
heat shock protein HSP 90-alpha isoform 20004
M-phase phosphoprotein 84004
muscarinic acetylcholine receptor M15005
neuropeptide S receptor isoform A3003
Intermediate conductance calcium-activated potassium channel protein 40101
Transient receptor potential cation channel subfamily M member 20101
Chymotrypsinogen A0404
Beta-lactamase0404
Sarcoplasmic/endoplasmic reticulum calcium ATPase 10101
Steroid 17-alpha-hydroxylase/17,20 lyase0606
Estrogen receptor0011
Tyrosine-protein kinase Fyn0404
Heme oxygenase 1 0303
ATP-dependent translocase ABCB10909
Epoxide hydrolase 10003
Aldo-keto reductase family 1 member B1010010
Beta-1 adrenergic receptor0617
Aromatase013013
Beta-3 adrenergic receptor0617
D(2) dopamine receptor0606
Androgen receptor010010
Alpha-1B adrenergic receptor0808
Potassium-transporting ATPase subunit beta0101
Potassium-transporting ATPase alpha chain 10101
5-hydroxytryptamine receptor 1A0618
ATP-dependent translocase ABCB10909
Substance-K receptor0808
D(1A) dopamine receptor0606
D(4) dopamine receptor0404
Potassium voltage-gated channel subfamily A member 30101
Acetylcholinesterase0819
Heme oxygenase 20303
Sodium-dependent noradrenaline transporter 010111
Thromboxane-A synthase 0505
Histamine H2 receptor010010
C-X-C chemokine receptor type 10202
Substance-P receptor0404
Platelet-activating factor receptor1203
5-hydroxytryptamine receptor 2A012012
5-hydroxytryptamine receptor 1B0606
Indoleamine 2,3-dioxygenase 10303
Vasopressin V2 receptor0101
Sodium-dependent serotonin transporter0606
Histamine H1 receptor0202
Mu-type opioid receptor0606
D(3) dopamine receptor010010
Malate dehydrogenase, cytoplasmic0404
Delta-type opioid receptor0606
Kappa-type opioid receptor0606
5-hydroxytryptamine receptor 2B0606
Alpha-1A adrenergic receptor0808
C-C chemokine receptor type 40101
Transitional endoplasmic reticulum ATPase0101
Guanine nucleotide-binding protein G4004
Cytochrome P450 1440055
Steroid C26-monooxygenase0055
Cytochrome P450 1300011
Cytochrome P450 1300011
Steroid C26-monooxygenase0055
Mycocyclosin synthase0033
Lanosterol 14-alpha demethylase0033
Nuclear receptor subfamily 1 group I member 3 0202
Lanosterol 14-alpha demethylase0729
Sterol 14-alpha demethylase0044
Estrogen receptor beta0011
Indoleamine 2,3-dioxygenase 20202
Bile acid receptor0101
14-alpha sterol demethylase 0044
Cysteinyl leukotriene receptor 10202
HSP40, subfamily A [Plasmodium falciparum 3D7]0002
heat shock protein 90, putative0004
Chain A, Beta-lactamase6006
GALC protein3003
muscleblind-like protein 1 isoform 15005
Exportin-10101
NAD-dependent histone deacetylase SIR20103
Cytochrome P450 2A60001
Aldo-keto reductase family 1 member B10707
UDP-glucuronosyltransferase 2B70203
Amine oxidase [flavin-containing] B0101
Cytochrome P450 2A50001
Amine oxidase [flavin-containing] A 0202
Acetylcholinesterase0101
UDP-glucuronosyltransferase 1A40202
Glyceraldehyde-3-phosphate dehydrogenase, glycosomal0101
Substance-P receptor0203
UDP-glucuronosyltransferase 2B10 0202
Quinone oxidoreductase0002
Sorbitol dehydrogenase0101
Induced myeloid leukemia cell differentiation protein Mcl-10202
Zn finger protein 0101
Dihydroorotate dehydrogenase 0101
Vascular endothelial growth factor receptor 20101
Histone acetyltransferase p3000101
CREB-binding protein0101
Acrosin0303
Suppressor of tumorigenicity 14 protein0303
Aldo-keto reductase family 1 member B100303
Prostaglandin G/H synthase 1 0405
Transient receptor potential cation channel subfamily A member 10123
Dihydrofolate reductase0202
Cytochrome c oxidase subunit 20202
Fatty acid-binding protein, liver0303
Transthyretin0125
Albumin0369
Interleukin-80202
Calcium/calmodulin-dependent protein kinase type II subunit alpha0101
Fatty acid-binding protein, intestinal0101
UDP-glucuronosyltransferase 1A30001
Prostaglandin G/H synthase 20505
Prostaglandin G/H synthase 20203
Carbonic anhydrase 40101
P2Y purinoceptor 120202
UDP-glucuronosyltransferase 1A70101
UDP-glucuronosyltransferase 1A100101
D(1A) dopamine receptor2002
Angiotensin-converting enzyme0404
Nuclear receptor subfamily 3 group C member 3 0404
Cereblon isoform 40202
Insulin-like growth factor-binding protein 50011
Choline O-acetyltransferase 0101
Protein cereblon0202
Eyes absent homolog 20101
Angiotensin-converting enzyme 0101
Beta-lactamase 0101
Beta-lactamase 0101
Motilin receptor0011
low molecular weight phosphotyrosine protein phosphatase isoform c0101
Motilin receptor0112
60 kDa chaperonin0303
60 kDa heat shock protein, mitochondrial0505
Chitinase B0101
Low molecular weight phosphotyrosine protein phosphatase0202
10 kDa heat shock protein, mitochondrial0505
Thiosulfate sulfurtransferase0404
60 kDa chaperonin 0505
10 kDa chaperonin 0505
unnamed protein product0101
Histone deacetylase 30303
Lanosterol 14-alpha demethylase0134
Cytochrome P450 11B1, mitochondrial0303
Cytochrome P450 11B2, mitochondrial0303
Histone deacetylase 40202
Lanosterol 14-alpha demethylase0011
Histone deacetylase 10303
Sterol 14-alpha demethylase0224
Histone deacetylase 70202
Histone deacetylase 20303
Polyamine deacetylase HDAC100101
Histone deacetylase 11 0202
Histone deacetylase 80202
Histone deacetylase 60202
Histone deacetylase 90101
Histone deacetylase 50202
likely tRNA 2'-phosphotransferase0101
Nuclear receptor subfamily 1 group I member 20011
Nuclear receptor subfamily 1 group I member 20011
Chain A, Uracil Phosphoribosyltransferase0101
Skn7p0001
serine/threonine-protein kinase mTOR isoform 13003
Vpr3003
Thymidylate synthase0101
Menin0011
Lecithin retinol acyltransferase0101
Lethal factor0101
Protein Rev 0022
Aminoglycoside 3'-phosphotransferase 0001
Tyrosyl-DNA phosphodiesterase 10303
Beta-galactosidase0101
Lipopolysaccharide heptosyltransferase 10101
PA-I galactophilic lectin0011
Jacalin0011
Chain A, Estrogen receptor 1 (alpha)0101
Chain A, Transthyretin0011
Chain A, Transthyretin0011
Neuraminidase 0101
P532002
Alpha-mannosidase0101
hexokinase-4 isoform 12002
NPC intracellular cholesterol transporter 1 precursor3003
parathyroid hormone/parathyroid hormone-related peptide receptor precursor7007
histone deacetylase 9 isoform 35005
glucokinase regulatory protein2002
tyrosine-protein kinase Yes1001
pyruvate kinase PKM isoform b1001
Maltase-glucoamylase, intestinal0404
Steroid hormone receptor ERR20101
Tyrosine-protein kinase ABL10203
Pancreatic triacylglycerol lipase0101
Triosephosphate isomerase0101
Estrogen receptor0516
Sex hormone-binding globulin0011
Ornithine decarboxylase1001
Sialidase0303
Solute carrier family 2, facilitated glucose transporter member 10101
Tyrosinase0303
Steroid hormone receptor ERR10101
Cyclin-dependent kinase 40101
Ornithine decarboxylase0202
Proto-oncogene tyrosine-protein kinase Src0101
Cystic fibrosis transmembrane conductance regulator0011
17-beta-hydroxysteroid dehydrogenase type 10101
Solute carrier family 2, facilitated glucose transporter member 40101
Dipeptidyl peptidase 40202
Protein kinase C alpha type0113
cAMP-dependent protein kinase catalytic subunit alpha0202
Amine oxidase [flavin-containing] A 0101
G1/S-specific cyclin-D10101
Cruzipain0101
DNA (cytosine-5)-methyltransferase 10101
Amine oxidase [flavin-containing] B0303
Proteasome subunit beta type-50101
Sodium-dependent serotonin transporter0303
RAC-alpha serine/threonine-protein kinase0202
Cystic fibrosis transmembrane conductance regulator0011
17-beta-hydroxysteroid dehydrogenase type 20101
Acetylcholinesterase0101
Alpha-glucosidase MAL320101
Signal transducer and activator of transcription 30202
Tyrosine-protein kinase CSK0101
Tyrosine-protein kinase ABL20101
Tyrosine-protein kinase SYK0101
Dual specificity mitogen-activated protein kinase kinase 40101
Cytoplasmic tyrosine-protein kinase BMX0101
Mitogen-activated protein kinase 100101
Oxysterols receptor LXR-beta0101
Amine oxidase [flavin-containing] B0101
Aldehyde oxidase0101
Oxysterols receptor LXR-alpha0101
Mitogen-activated protein kinase 140101
Tissue alpha-L-fucosidase0101
Substance-K receptor0101
Estrogen receptor beta0415
Beta-hydroxyacyl-ACP dehydratase precursor (Fatty acid synthesis protein)0101
Prenyltransferase homolog0002
Carboxylic ester hydrolase 0101
Solute carrier organic anion transporter family member 1B30505
Dipeptidyl peptidase 30101
DNA (cytosine-5)-methyltransferase 3-like0101
DNA (cytosine-5)-methyltransferase 3A0101
Solute carrier organic anion transporter family member 1B10506
beta-amyloid peptide, A beta {N-terminal} [human, cerebrospinal fluid, conditioned medium of mixed-brain cell cultures, Peptide Partial, 33 aa]1001
alpha synuclein, partial1001
luciferase2002
Glutamate receptor ionotropic, kainate 11001
Glutamate receptor ionotropic, kainate 21001
Glutamate receptor ionotropic, kainate 31001
Inositol monophosphatase 15005
Glutamate receptor ionotropic, kainate 41001
Leukotriene B4 receptor 11001
Glutamate receptor ionotropic, kainate 51001
Leukotriene B4 receptor 21001
Aldo-keto reductase family 1 member C30303
Aldo-keto reductase family 1 member C2 0202
Aldo-keto reductase family 1 member C10202
Chain E, Fibrin beta chain0101
Mcl-10101
MPI protein0101
Cyclin-dependent kinase 5, regulatory subunit 1 (p35)0001
alkaline phosphatase, intestinal0011
thioredoxin glutathione reductase2002
CDK50001
serine-protein kinase ATM isoform a2002
major prion protein preproprotein Prp precursor0101
alkaline phosphatase, tissue-nonspecific isozyme isoform 1 preproprotein0011
intestinal alkaline phosphatase precursor0011
Vif0202
Tat0101
DNA dC->dU-editing enzyme APOBEC-3G isoform 10202
alkaline phosphatase, germ cell type preproprotein0011
endoribonuclease toxin MazF0011
DNA dC->dU-editing enzyme APOBEC-3F isoform a1001
Pyruvate kinase PKM0112
Endothelin receptor type B3003
Endothelin-1 receptor3003
hypothetical protein CAALFM_CR05890CA0001
H3 histone acetyltransferase0001
large T antigen0303
Protein arginine N-methyltransferase 50202
Protein arginine N-methyltransferase 10202
Chain A, membrane-associated prostaglandin E synthase-20101
Prostaglandin-H2 D-isomerase0101
Prostaglandin E synthase0101
Prostaglandin G/H synthase 2 0203
3',5'-cyclic-AMP phosphodiesterase 0202
Solute carrier organic anion transporter family member 2B1 0202
Phospholipase A2, major isoenzyme0202
Aldo-keto reductase family 1 member B10101
Aldo-keto reductase family 1 member C40101
Prostaglandin G/H synthase 10101
Sodium-dependent dopamine transporter0101
Serum paraoxonase/arylesterase 10101
Caspase-10001
Nitric oxide synthase, inducible0202
Prostaglandin E2 receptor EP3 subtype0101
Prostaglandin E2 receptor EP4 subtype0101
Multidrug resistance-associated protein 1 0101
Bifunctional epoxide hydrolase 20101
Prostaglandin E2 receptor EP1 subtype0101
Peroxisome proliferator-activated receptor gamma0011
C-X-C chemokine receptor type 30101
Prostaglandin D2 receptor 0202
Solute carrier organic anion transporter family member 1A30101
Uracil nucleotide/cysteinyl leukotriene receptor0101
Sigma intracellular receptor 20101
Prostaglandin E2 receptor EP2 subtype0101
Rho-associated protein kinase 20202
Nicotinate phosphoribosyltransferase0202
Dehydrogenase/reductase SDR family member 90101
Prostaglandin D2 receptor 20112
Chain B, Pulmonary surfactant-associated protein D0101
Chain A, Pulmonary surfactant-associated protein D0101
Sodium/myo-inositol cotransporter 20101
Acetylcholinesterase0404
Acetylcholinesterase0011
Lysosomal protective protein0101
Fatty acid synthase 0101
Liver carboxylesterase0101
Estrogen receptor beta0113
25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial0101
25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial0202
Cytochrome P450 26A10101
Camphor 5-monooxygenase0001
Cytochrome P450 2C11 0101
Steroid 21-hydroxylase0101
Cytochrome P450 2C80102
Steroid 17-alpha-hydroxylase/17,20 lyase 0101
Cholesterol side-chain cleavage enzyme, mitochondrial 0101
5-hydroxytryptamine receptor 2A0101
Indoleamine 2,3-dioxygenase 10202
Cytochrome P450 2A20101
Cytochrome P450 11B1, mitochondrial 0101
Translocator protein0101
Cytochrome P450 7A1 0101
Estrogen receptor0113
Gonadotropin-releasing hormone receptor0112
Type-1 angiotensin II receptor0101
Cytochrome P450 4F20101
1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial0202
1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial0101
Sodium/bile acid cotransporter0101
Cytochrome P450 7A10101
Lanosterol 14-alpha demethylase 0202
Chain A, Lectin0011
Chain A, Lectin0011
Chain A, Lectin0011
Chain A, Lectin0011
Chain A, ERYTHRINA CRISTA-GALLI LECTIN0011
Chain A, ERYTHRINA CRISTA-GALLI LECTIN0011
Chain A, cellulase0011
Chain A, cellulase0011
Chain A, Galectin-30011
Chain A, Anti-tumor lectin0101
Galectin-30101
Galectin-90011
Galectin-80011
Beta-galactoside-binding lectin0101
Galectin-10113
Galectin-30112
Galectin-30113
Galectin-70011
Alpha 1,4 galactosyltransferase0001
CAAX prenyl protease 2 isoform 20001
Tubulin beta-4A chain0101
Tubulin beta chain0101
Tubulin alpha-3C chain0101
Tubulin alpha-1B chain0101
Tubulin alpha-4A chain0101
Tubulin beta-4B chain0101
DNA primase0101
Tubulin beta-3 chain0101
Tubulin beta-2A chain0101
Tubulin beta-8 chain0101
Tubulin alpha-3E chain0101
Tubulin alpha-1A chain0101
Tubulin alpha-1C chain0101
Tubulin beta-6 chain0101
Tubulin beta-2B chain0101
Tubulin beta-1 chain0101
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ0101
Isocitrate dehydrogenase [NADP] cytoplasmic0101
Sphingomyelin phosphodiesterase0101
Tyrosine-protein phosphatase non-receptor type 109011
Phosphoglycerate mutase 10101
Nuclear factor NF-kappa-B p105 subunit0202
Delta-type opioid receptor0203
7,8-dihydro-8-oxoguanine triphosphatase0101
Fatty acid synthase0101
Mu-type opioid receptor0101
Transcription factor p650303
cAMP-specific 3',5'-cyclic phosphodiesterase 4D0101
Sphingomyelin phosphodiesterase0101
Probable maltase-glucoamylase 20202
Stimulator of interferon genes protein0011
Stimulator of interferon genes protein0112
Cyclic GMP-AMP synthase0101
MAP/microtubule affinity-regulating kinase 40101
Alpha-mannosidase 2C10101
Fucose-binding lectin PA-IIL0101
CD209 antigen0101
Metallo-beta-lactamase VIM-19 0001
Beta-lactamase 0001
Beta-lactamase 0001
Beta-lactamase 0012
Beta-lactamase IMP-1 0001
BlaVIM-1 0001
Beta-lactamase 0001
Beta-lactamase 0001
Thioredoxin reductase 0101
Flavodoxin0001
Voltage-dependent L-type calcium channel subunit alpha-1F0303
Voltage-dependent L-type calcium channel subunit alpha-1D 0303
Voltage-dependent L-type calcium channel subunit alpha-1S0303
Metabotropic glutamate receptor 60101
Cytochrome P450 1A20101
Cytochrome P450 1A2 0101
Cannabinoid receptor 10202
Aromatase0011
Melanocortin receptor 40202
Melanocortin receptor 50202
Melanocortin receptor 30202
Type-2 angiotensin II receptor0202
Cholinesterase0303
Calcium release-activated calcium channel protein 10101
methionyl-tRNA synthetase, putative0101
Platelet-activating factor receptor0101
M-phase inducer phosphatase 10101
Nuclear receptor corepressor 10101
Integrin beta-10101
Leukotriene A-4 hydrolase0202
Integrin alpha-40101
Nuclear receptor corepressor 20101
DNA gyrase subunit B0101
Potassium voltage-gated channel subfamily E member 10101
Potassium voltage-gated channel subfamily KQT member 10101
pyruvate kinase PKM isoform a1001
Pyruvate-flavodoxin oxidoreductase0101
Anoctamin-10101
STE240001
Trypsin0102
Chain A, Adipocyte Lipid-binding Protein0011
Chain A, SERUM ALBUMIN0011
Chain A, SERUM ALBUMIN0011
Chain A, MUSCLE FATTY ACID BINDING PROTEIN0011
Chain A, MUSCLE FATTY ACID BINDING PROTEIN0011
Chain A, MUSCLE FATTY ACID BINDING PROTEIN0011
putative potassium channel subunit0011
histone-lysine N-methyltransferase 2A isoform 2 precursor1001
Sterol O-acyltransferase 10101
Fatty acid-binding protein, liver0011
Coagulation factor VII0101
DNA topoisomerase 10101
Tissue factor0101
Fatty acid-binding protein, adipocyte0202
Sterol O-acyltransferase 10101
Fatty acid-binding protein 50101
Peroxisome proliferator-activated receptor delta0001
Peroxisome proliferator-activated receptor alpha1023
Transient receptor potential cation channel subfamily V member 20101
Chain A, Breast cancer type 1 susceptibility protein2002
Non-structural protein 1 0101
Protein tyrosine phosphatase type IVA 30101
Protein S100-B0112
Protein S100-B0011
Amiloride-sensitive amine oxidase [copper-containing]0101
Diamine acetyltransferase 10101
Glutamate receptor ionotropic, NMDA 10303
Glutamate receptor ionotropic, NMDA 2A0303
Protein tyrosine phosphatase type IVA 20101
Protein tyrosine phosphatase type IVA 10101
Chain A, Immunoglobulin0011
Chain B, Immunoglobulin0011
Glutamate receptor ionotropic, NMDA 2D0101
Glutamate receptor ionotropic, NMDA 3B0101
Cytochrome P450 2B60202
Kappa-type opioid receptor0001
Glutamate receptor ionotropic, NMDA 1 0303
Lysosomal Pro-X carboxypeptidase0101
Mu-type opioid receptor0001
Glutamate receptor ionotropic, NMDA 2A 0303
Glutamate receptor ionotropic, NMDA 2B0303
Glutamate receptor ionotropic, NMDA 2C0304
Cholinesterase0101
Glutamate receptor ionotropic, NMDA 2B0202
Glutamate receptor ionotropic, NMDA 2C0101
Glutamate receptor ionotropic, NMDA 2D0303
Glutamate receptor ionotropic, NMDA 3A0101
Glutamate receptor ionotropic, NMDA 3B0303
Muscarinic acetylcholine receptor M50012
Muscarinic acetylcholine receptor M30012
Muscarinic acetylcholine receptor M20012
Sigma non-opioid intracellular receptor 10202
Glutamate receptor ionotropic, NMDA 3A0303
dopamine D1 receptor2002
Alpha-1B adrenergic receptor 0011
Beta-2 adrenergic receptor0213
POU domain, class 2, transcription factor 10001
Beta-1 adrenergic receptor0202
Alpha-1A adrenergic receptor0112
Alpha-1B adrenergic receptor0101
Alpha-1D adrenergic receptor0202
Alpha-2B adrenergic receptor0001
Alpha-2C adrenergic receptor0001
Alpha-2A adrenergic receptor0001
Neutrophil elastase0202
Myeloblastin0101
Sterol 14-alpha-demethylase0022
14-alpha sterol demethylase 0022
14-alpha sterol demethylase 0022
luciferase0001
Glucocorticoid receptor0112
Glucocorticoid receptor0011
Corticosteroid-binding globulin0101
Mineralocorticoid receptor 0213
Glutamine synthetase0011
Histamine H1 receptor0011
Nociceptin receptor0011
Cytochrome P450 3A50001
ATP-binding cassette sub-family C member 80112
Chain A, Troponin C, slow skeletal and cardiac muscles0011
Chain A, Leukotriene A-4 hydrolase0101
Chain A, Leukotriene A-4 hydrolase0101
Chain A, Leukotriene A-4 hydrolase0101
Chain A, Leukotriene A-4 hydrolase0101
Chain A, Leukotriene A-4 hydrolase0101
Chain A, Leukotriene A-4 hydrolase0101
Chain A, Leukotriene A-4 hydrolase0101
Chain A, Leukotriene A-4 hydrolase0101
Chain A, Leukotriene A-4 hydrolase0101
Chain A, Leukotriene A-4 hydrolase0101
Chain A, Leukotriene A-4 hydrolase0101
Chain A, Leukotriene A-4 hydrolase0101
Chain A, Leukotriene A-4 hydrolase0101
Chain A, Leukotriene A-4 hydrolase0101
Chain A, Leukotriene A-4 hydrolase0101
Chain A, Leukotriene A-4 hydrolase0101
Chain A, Leukotriene A-4 hydrolase0101
ClpP1001
M18 aspartyl aminopeptidase0101
cathepsin L10101
atrial natriuretic peptide receptor 2 precursor1001
FAD-linked sulfhydryl oxidase ALR0001
transcription factor p65 isoform 10011
serine/threonine-protein kinase 33 isoform a0011
POsterior Segregation0011
Aryl hydrocarbon receptor0101
Polyphenol oxidase 20203
Myc proto-oncogene protein0102
Tyrosine-protein kinase Lck0101
Cholinesterase0101
Cathepsin D0101
Luciferin 4-monooxygenase0101
DNA polymerase alpha catalytic subunit0101
Breakpoint cluster region protein0102
Tyrosinase0101
ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 10101
Cannabinoid receptor 10101
D(1A) dopamine receptor1001
Alpha-glucosidase MAL120101
Nuclear factor NF-kappa-B p100 subunit 0101
Squalene synthase0101
cAMP-specific 3',5'-cyclic phosphodiesterase 4B0001
Bcl-2-like protein 10101
Serine/threonine-protein kinase PAK 10101
Nuclear factor erythroid 2-related factor 20012
N1L 0101
NAD(P)H dehydrogenase [quinone] 10002
Tubulin beta-2B chain0101
Lysosomal alpha-glucosidase0101
Transient receptor potential cation channel subfamily A member 10101
Similar to alpha-tubulin isoform 1 0101
Similar to alpha-tubulin isoform 1 0101
NAD-dependent protein deacetylase sirtuin-20011
NAD-dependent protein deacetylase sirtuin-10013
NAD-dependent protein deacetylase sirtuin-3, mitochondrial0011
Zinc finger protein mex-50011
Chain A, 6,7-Dimethyl-8-ribityllumazine Synthase0011
Chain B, 6,7-Dimethyl-8-ribityllumazine Synthase0011
Chain H, Immunoglobulin Igg1 Heavy chain0011
Chain L, Immunoglobulin Igg1 Lambda Light Chain0011
Chain A, DODECIN0011
Chain A, DODECIN0011
Chain C, DODECIN0011
Chain E, DODECIN0011
caspase-1 isoform alpha precursor1001
Caspase-71001
chaperonin-containing TCP-1 beta subunit homolog1001
Inhibitor of nuclear factor kappa-B kinase subunit beta0001
5'-AMP-activated protein kinase subunit beta-20001
Polymerase acidic protein0011
Tyrosine-protein phosphatase YopH0101
High mobility group protein B10011
Prolyl 4-hydroxylase subunit alpha-10101
Cystathionine gamma-lyase0101
5'-AMP-activated protein kinase subunit gamma-10001
5'-AMP-activated protein kinase catalytic subunit alpha-20001
5'-AMP-activated protein kinase catalytic subunit alpha-10001
Carbonic anhydrase0101
Solute carrier family 22 member 200202
Solute carrier family 22 member 60202
Ubiquitin-like domain-containing CTD phosphatase 10101
5'-AMP-activated protein kinase subunit gamma-30001
5'-AMP-activated protein kinase subunit gamma-20001
5'-AMP-activated protein kinase subunit beta-10001
Neutral amino acid transporter A0101
Neutral amino acid transporter B(0)0101
Proton-coupled amino acid transporter 10202
Amino acid transporter0101
Sodium- and chloride-dependent taurine transporter0101
Nrf21001
Caspase 6, apoptosis-related cysteine peptidase0001
toll-like receptor 90101
caspase recruitment domain family, member 150101
neurotensin receptor type 10011
receptor-interacting serine/threonine-protein kinase 2 isoform 10101
GTP-binding nuclear protein Ran isoform 11001
Beta lactamase (plasmid)0101
Beta-1 adrenergic receptor 0011
Beta-2 adrenergic receptor0011
Chain A, RIO-type serine/threonine-protein kinase Rio10011
Glycogen phosphorylase, muscle form0101
Basic phospholipase A2 10101
Pancreatic alpha-amylase0101
Hemagglutinin0011
DNA polymerase beta0101
DNA polymerase beta0101
Receptor-type tyrosine-protein phosphatase F0202
Cholesteryl ester transfer protein0101
Fatty acid synthase0101
Tyrosine-protein phosphatase non-receptor type 20202
Receptor-type tyrosine-protein phosphatase alpha0101
Liver carboxylesterase 10101
Receptor-type tyrosine-protein phosphatase epsilon0101
Corticosteroid 11-beta-dehydrogenase isozyme 10101
Tyrosine-protein phosphatase non-receptor type 60202
Basic phospholipase A2 PLA-A0101
Hypoxia-inducible factor 1-alpha0101
Env polyprotein 0011
Acidic phospholipase A2 EC-I0101
G-protein coupled bile acid receptor 10011
Ubiquitin carboxyl-terminal hydrolase 70101
Ubiquitin carboxyl-terminal hydrolase 470101
Prolyl hydroxylase EGLN20011
Ghrelin O-acyltransferase0101
Egl nine homolog 10011
Prolyl hydroxylase EGLN30011
Transmembrane prolyl 4-hydroxylase0011
Sentrin-specific protease 10101
Protease 0101
Solute carrier family 15 member 10101
Valacyclovir hydrolase0001
Tyrosine-protein phosphatase non-receptor type 110101
D-alanyl-D-alanine dipeptidase0101
Transporter0101
Dipeptidyl peptidase 90101
Dipeptidyl peptidase IV0202
Kynurenine 3-monooxygenase0101
Heat shock protein HSP 90-beta0101
Dipeptidyl peptidase 40101
Prolyl endopeptidase FAP0101
Prolyl endopeptidase FAP0101
Dipeptidyl peptidase 80202
Dipeptidyl peptidase 90202
Dipeptidyl peptidase 20101
Cholesterol side-chain cleavage enzyme, mitochondrial 0011
Cholesterol 24-hydroxylase0213
Albumin0011
Proprotein convertase subtilisin/kexin type 70101
Vitamin K epoxide reductase complex subunit 1-like protein 10101
Vitamin K epoxide reductase complex subunit 10101
Protease 0101
Vitamin K epoxide reductase complex subunit 1-like protein 10101
Vitamin K epoxide reductase complex subunit 1 0202
Chain E, cAMP-dependent protein kinase, alpha-catalytic subunit0101
Chain I, cAMP-dependent protein kinase inhibitor, alpha form0101
Chain B, Rho-associated protein kinase 10101
Chain A, Rho-associated protein kinase 10101
Chain A, Rho-associated protein kinase 10101
Chain A, cAMP-dependent protein kinase, alpha-catalytic subunit0101
Chain A, cAMP-dependent protein kinase, alpha-catalytic subunit0101
Chain A, cAMP-dependent protein kinase, alpha-catalytic subunit0101
Chain I, cAMP-dependent protein kinase inhibitor alpha0101
Chain A, cAMP-dependent protein kinase, alpha-catalytic subunit0101
Chain A, cAMP-dependent protein kinase, alpha-catalytic subunit0101
Chain I, cAMP-dependent protein kinase inhibitor alpha0101
Chain A, Rho-associated protein kinase 10101
Rho-associated protein kinase 20202
Ribosomal protein S6 kinase alpha-50101
cAMP-dependent protein kinase catalytic subunit alpha0101
cAMP-dependent protein kinase catalytic subunit alpha 0101
C-C motif chemokine 20101
cAMP-dependent protein kinase catalytic subunit gamma0101
cAMP-dependent protein kinase catalytic subunit beta0101
Rho-associated protein kinase 10202
Serine/threonine-protein kinase N20101
Rho-associated protein kinase 20101
twin arginine protein translocation system - TatA protein0001
Protein-arginine deiminase type-40101
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]