Hemophilia B

A deficiency of blood coagulation factor IX inherited as an X-linked disorder. (Also known as Christmas Disease, after the first patient studied in detail, not the holy day.) Historical and clinical features resemble those in classic hemophilia (HEMOPHILIA A), but patients present with fewer symptoms. Severity of bleeding is usually similar in members of a single family. Many patients are asymptomatic until the hemostatic system is stressed by surgery or trauma. Treatment is similar to that for hemophilia A. (From Cecil Textbook of Medicine, 19th ed, p1008)

Synonym
Hemophilia B

Excerpt	Reference
"Hemophilia B is caused by a deficiency of blood clotting factor IX (FIX)."	( Bellinger, DA; Cross, RE; Eisensmith, RC; Fang, B; Gordon, G; Hu, PC; Kay, MA; Landen, CN; Read, MS; Wang, H, 1995)
"Hemophilia B is an X-chromosome-linked recessive disorder that is caused by a deficiency of biologically active clotting factor IX (FIX)."	( Axelrod, JH; Baru, M; Nur, I, 1995)
"Hemophilia B is a sex-linked recessive bleeding disorder characterized by the presence of either a decreased amount of normal factor IX (FIX) or the presence of a dysfunctional FIX."	( Haver, T; Jacobson, L; Lefkowitz, JB; Manco-Johnson, M; Nuss, R; Thompson, AR, 2001)
"Hemophilia B is an X-linked, recessive disorder of hemostasis, caused by a defect in coagulation factor IX."	( Chowdhury, MR; Kabra, M; Menon, PS, 2001)
"Hemophilia B is an X-linked recessive, bleeding disorder caused by mutations in the factor IX gene."	( Bharadwaj, D; Chavali, S; Chowdhury, MR; Kabra, M; Mahajan, A, 2004)
"Hemophilia B is an X-linked recessively inherited bleeding disorder afflicting humans across all socio-economic as well as racial groups."	( Ghosh, K; Quadros, L; Shetty, S, 2007)
"Hemophilia B is an inherited X-linked recessive bleeding disorder, due to a defect in human factor IX (FIX)."	( Dargaud, Y; Enjolras, N; Girard, J; Indalecio, A; Le Quellec, S; Negrier, C; Perot, E, 2015)
"Hemophilia A and hemophilia B are hereditary bleeding disorders, caused by a deficiency of clotting factor VIII or clotting factor IX, respectively."	( Cnossen, MH; Kruip, MJHA; Leebeek, FWG; Mathôt, RAA; Preijers, T; Schütte, LM; van Hest, RM, 2019)
"Hemophilia B is associated with molecular heterogeneity, with more than 1200 unique variants in the F9 gene."	( Agrawal, N; Jaiswal, SK; Kumar, R; Mandal, K; Masih, S; Moirangthem, A; Phadke, SR; Saxena, D; Singh, P; Srivastava, P, 2022)

Excerpt	Reference
"In the treatment of a hemophilia B patient showing decreased platelet counts, these counts increased consistent with the administration of Acyclovir and Zidovudine."	( Fukutake, K; Koike, K; Sugimura, D; Takahashi, Y; Tateyama, M; Yamamoto, Y; Yorifuji, H; Yoshida, S, 1993)
"The main treatment for hemophilia B is replacement therapy using FIX concentrates."	( Dargaud, Y; Enjolras, N; Girard, J; Indalecio, A; Le Quellec, S; Negrier, C; Perot, E, 2015)

Timeframe	Studies, This Condition (%)	All Conditions %
pre-1990	371 (50.34)	23.3326
1990's	122 (16.55)	12.5806
2000's	119 (16.15)	18.1394
2010's	103 (13.98)	28.8240
2020's	22 (2.99)	9.53

Drug	Relationship Strength	Studies	Trials
acetaldehyde	low	1	0
adenine	low	3	0
ammonium hydroxide	low	1	0
carbon monoxide	low	1	0
catechol	low	1	0
choline	low	1	0
citric acid, anhydrous	low	1	0
chlorine	low	4	0
coumarin	low	2	0
salicylic acid	low	1	0
gallic acid	low	1	0
aminocaproic acid	medium	14	2
cytosine	low	2	0
lactic acid	low	2	0
glycine	low	6	0
dalteparin	medium	1	1
dihydroxyphenylalanine	low	1	0
nitrites	low	1	0
purine	low	1	0
pyrogallol	low	1	0
urea	medium	2	1
aminopropionitrile	low	1	0
4-aminobenzamidine	low	3	0
acetaminophen	low	2	0
aspirin	medium	9	1
azathioprine	low	1	0
propiolactone	low	2	0
busulfan	low	1	0
celecoxib	low	2	0
chloroquine	low	1	0
chlorpheniramine	low	1	0
diphenhydramine	low	2	0
ether	low	1	0
fluconazole	low	1	0
furosemide	low	2	0
gentamicin	low	1	0
guaifenesin	low	1	0
hydroxyurea	low	1	0
ibuprofen	low	1	0
isoflurane	low	1	0
meperidine	low	2	0
methadone	low	1	0
nitroglycerin	low	1	0
phenacetin	low	1	0
phenindione	low	3	0
4-phenylbutyric acid	low	1	0
pyrimethamine	low	1	0
rofecoxib	low	1	0
tranexamic acid	medium	19	3
prednisolone	medium	9	3
thyroxine	low	4	0
lynestrenol	medium	2	1
prednisone	medium	12	1
triiodothyronine	low	1	0
isoflurophate	low	2	0
alanine	low	4	0
serine	low	4	0
glutamine	low	3	0
lysine	low	3	0
adenosine diphosphate	low	1	0
uridine monophosphate	low	1	0
edetic acid	low	8	0
tyrosine	low	3	0
leucine	low	2	0
phenylalanine	low	3	0
colchicine	low	2	0
cytidine triphosphate	low	1	0
triamcinolone diacetate	low	1	0
asparagine	low	1	0
histidine	low	3	0
valine	low	7	0
threonine	low	1	0
mestranol	medium	2	1
tryptophan	low	1	0
isoleucine	low	2	0
arginine	low	11	0
tromethamine	low	1	0
pyrrolidonecarboxylic acid	low	1	0
diatrizoate meglumine	low	1	0
n-heptane	low	2	0
pyrimidine	low	1	0
pyrazines	low	2	0
ephedrine	low	1	0
cyanogen bromide	low	1	0
copper gluconate	low	1	0
maleimide	low	1	0
erythromycin	low	1	0
ethylestrenol	low	1	0
durapatite	low	1	0
digoxigenin	low	2	0
hepes	low	1	0
rhenium	low	4	0
samarium	low	1	0
technetium	low	2	0
acetylglucosamine	low	2	0
ferric chloride	low	4	0
barium sulfate	low	3	0
calcium phosphate, dibasic, anhydrous	low	1	0
calcium phosphate, monobasic, anhydrous	low	1	0
tricalcium phosphate	low	3	0
fluorine	low	1	0
trolamine salicylate	medium	14	1
stanozolol	medium	2	1
danazol	medium	11	2
osmium tetroxide	low	1	0
cetylpyridinium chloride anhydrous	low	1	0
triamcinolone	low	1	0
transferrin	low	1	0
glutamic acid	low	2	0
zidovudine	low	4	0
acetylgalactosamine	medium	5	1
ribavirin	low	5	0
1-carboxyglutamic acid	low	2	0
propiconazole	low	1	0
yttrium citrate	low	1	0
ibandronic acid	medium	1	1
capecitabine	low	1	0
1,2-distearoyllecithin	low	1	0
testosterone undecanoate	low	1	0
5-bromo-4-chloro-3-indolyl beta-galactoside	low	1	0
fluorodeoxyglucose f18	low	1	0
fibrinogen	medium	56	6
glucuronic acid	low	2	0
yttrium radioisotopes	low	5	0
phenylalanyl-prolyl-arginine-chloromethyl ketone	low	1	0
dansylglutamyl-glycyl-arginine chloromethyl ketone	low	1	0
antibiotic g 418	low	1	0
4-azido-7-phenylpyrazolo-(1,5a)-1,3,5-triazine	low	1	0
factor xiiib	low	1	0
s 2366	low	1	0
olmesartan medoxomil	low	1	0
thiobenzyl benzyloxycarbonyl-l-lysinate	low	1	0
calcium pyrophosphate	low	1	0
cortisone	low	1	0
trimethoprim, sulfamethoxazole drug combination	low	1	0
bortezomib	low	2	0
ritonavir	low	1	0
fibrin	medium	16	1
elastin	low	1	0
oxytocin	low	1	0
inositol 3-phosphate	low	1	0
tacrolimus	medium	2	1
mycophenolic acid	low	5	0
melphalan	low	1	0
bromochloroacetic acid	low	1	0
arginine vasopressin	low	2	0
leuprolide	low	1	0
ranitidine	low	1	0
dermatan sulfate	low	1	0
ovalbumin	low	1	0
sodium dodecyl sulfate	low	1	0
alpha-chymotrypsin	low	1	0
osteoprotegerin	low	1	0
bilirubin	low	2	0
calcitriol	low	1	0
vitamin k semiquinone radical	low	27	0
thromboxane a2	low	1	0
vitamin k1 oxide	low	1	0
ellagic acid	low	2	0
phenylephrine hydrochloride	low	2	0
acitretin	low	1	0
vitamin k 1	low	5	0
deamino arginine vasopressin	medium	18	1
strontium	low	1	0
indinavir sulfate	low	2	0
cysteine	low	1	0
rifamycin sv	low	1	0
selenium	low	1	0
oxalates	low	1	0
gadolinium dtpa	low	1	0
morphinans	low	1	0
losartan potassium	low	2	0
sepharose	low	3	0
pituitrin	low	1	0
rifamycins	low	1	0
clove	low	1	0
acid phosphatase	low	1	0
beta-endorphin	low	1	0
tannins	low	1	0
oligonucleotides	low	5	0
ristocetin	low	4	0
cellulose	low	3	0
phosphatidylcholines	low	4	0
chitosan	low	1	0
sodium ethylxanthate	low	1	0
pci 32765	low	1	0
intrinsic factor	low	1	0
fibrinopeptide a	medium	5	1
piperidines	low	2	0
sofosbuvir	low	1	0
dicumarol	low	6	0
acenocoumarol	low	3	0
warfarin	medium	29	1
6-s-hexadecyl-2-methoxythioascorbic acid	low	1	0
epidermal growth factor	low	10	0
kaolinite	low	13	0
transforming growth factor beta	low	1	0
hirudin	low	3	0
hyaluronoglucosaminidase	low	1	0
epoetin alfa	low	1	0
vitamin b 12	low	1	0
cyclosporine	low	2	0
thromboplastin	medium	119	1
muramidase	low	1	0
chondroitin sulfates	low	2	0
exudates	low	2	0
acyclovir	low	1	0
guanine	low	3	0
neopterin	low	1	0
rifampin	low	1	0
cytidylyl-3'-5'-guanosine	low	6	0
concanavalin a	low	1	0
metallothionein	low	1	0
phosphorus radioisotopes	low	4	0

Protein Targets (1,706)

Protein	Potency Measurements	Inhibition Measurements	Activation Measurements	Drugs
dopamine D1 receptor	2	0	0	2
Thrombopoietin	5	0	0	5
regulator of G-protein signaling 4	12	0	0	12
euchromatic histone-lysine N-methyltransferase 2	39	0	0	39
muscarinic acetylcholine receptor M1	11	0	0	11
Urokinase-type plasminogen activator	0	3	0	3
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE	16	0	0	16
Chain A, AROMATIC AMINO ACID AMINOTRANSFERASE	0	0	1	1
Chain B, AROMATIC AMINO ACID AMINOTRANSFERASE	0	0	1	1
Chain A, AROMATIC AMINO ACID AMINOTRANSFERASE	0	0	1	1
Chain B, AROMATIC AMINO ACID AMINOTRANSFERASE	0	0	1	1
Chain A, AROMATIC AMINO ACID AMINOTRANSFERASE	0	0	1	1
Chain B, AROMATIC AMINO ACID AMINOTRANSFERASE	0	0	1	1
Chain A, AROMATIC AMINO ACID AMINOTRANSFERASE	0	0	1	1
Chain B, AROMATIC AMINO ACID AMINOTRANSFERASE	0	0	1	1
Chain A, AROMATIC AMINO ACID AMINOTRANSFERASE	0	0	1	1
Chain B, AROMATIC AMINO ACID AMINOTRANSFERASE	0	0	1	1
Chain A, AROMATIC AMINO ACID AMINOTRANSFERASE	0	0	1	1
Chain B, AROMATIC AMINO ACID AMINOTRANSFERASE	0	0	1	1
Chain A, AROMATIC AMINO ACID AMINOTRANSFERASE	0	0	1	1
Chain B, AROMATIC AMINO ACID AMINOTRANSFERASE	0	0	1	1
Chain A, AROMATIC AMINO ACID AMINOTRANSFERASE	0	0	1	1
Chain B, AROMATIC AMINO ACID AMINOTRANSFERASE	0	0	1	1
Chain A, AROMATIC AMINO ACID AMINOTRANSFERASE	0	0	1	1
Chain B, AROMATIC AMINO ACID AMINOTRANSFERASE	0	0	1	1
mitogen-activated protein kinase 1	11	0	0	11
survival motor neuron protein isoform d	15	0	0	15
Histone deacetylase 3	0	5	0	5
Histone deacetylase 4	0	4	0	4
Histone deacetylase 1	0	5	0	5
Histone deacetylase 7	0	4	0	4
Histone deacetylase 2	0	5	0	5
Polyamine deacetylase HDAC10	0	3	0	3
Histone deacetylase 11	0	3	0	3
Histone deacetylase 8	0	5	0	5
NAD-dependent protein deacylase sirtuin-5, mitochondrial	0	1	0	1
Histone deacetylase 6	0	5	0	5
Histone deacetylase 9	0	4	0	4
Histone deacetylase 5	0	4	0	4
Luciferase	17	0	0	17
RAR-related orphan receptor gamma	46	0	0	46
retinoid X nuclear receptor alpha	32	0	0	32
G	17	0	0	17
peroxisome proliferator activated receptor gamma	36	0	0	36
thyroid stimulating hormone receptor	18	0	0	18
chromobox protein homolog 1	27	0	0	27
parathyroid hormone/parathyroid hormone-related peptide receptor precursor	7	0	0	7
geminin	44	0	0	44
muscleblind-like protein 1 isoform 1	12	0	0	12
Interferon beta	27	0	0	27
HLA class I histocompatibility antigen, B alpha chain	17	0	0	17
Guanine nucleotide-binding protein G	2	0	0	2
Inositol hexakisphosphate kinase 1	17	0	0	17
cytochrome P450 2C9, partial	17	0	0	17
acetylcholinesterase	12	0	0	12
hypoxia-inducible factor 1 alpha subunit	14	0	0	14
SMAD family member 2	16	0	0	16
SMAD family member 3	16	0	0	16
GLI family zinc finger 3	38	0	0	38
AR protein	54	0	0	54
caspase 7, apoptosis-related cysteine protease	10	0	0	10
thyroid stimulating hormone receptor	19	0	0	19
estrogen receptor 2 (ER beta)	25	0	0	25
nuclear receptor subfamily 1, group I, member 3	32	0	0	32
progesterone receptor	27	0	0	27
glucocorticoid receptor [Homo sapiens]	46	0	0	46
retinoic acid nuclear receptor alpha variant 1	44	0	0	44
estrogen-related nuclear receptor alpha	49	0	0	49
farnesoid X nuclear receptor	29	0	0	29
pregnane X nuclear receptor	41	0	0	41
estrogen nuclear receptor alpha	66	0	0	66
peroxisome proliferator-activated receptor delta	26	0	0	26
vitamin D (1,25- dihydroxyvitamin D3) receptor	21	0	0	21
caspase-3	10	0	0	10
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a	32	0	0	32
activating transcription factor 6	13	0	0	13
thyrotropin-releasing hormone receptor	4	0	0	4
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a	12	0	0	12
v-jun sarcoma virus 17 oncogene homolog (avian)	27	0	0	27
Histone H2A.x	23	0	0	23
Caspase-7	6	0	0	6
caspase-3	6	0	0	6
thyroid hormone receptor beta isoform 2	39	0	0	39
heat shock protein beta-1	17	0	0	17
nuclear factor erythroid 2-related factor 2 isoform 1	44	0	0	44
Voltage-dependent calcium channel gamma-2 subunit	24	0	0	24
Cellular tumor antigen p53	41	0	0	41
Glutamate receptor 2	26	3	1	30
ATPase family AAA domain-containing protein 5	19	0	0	19
Ataxin-2	24	0	0	24
ATAD5 protein, partial	8	0	0	8
GLS protein	20	0	0	20
Microtubule-associated protein tau	15	0	0	15
Smad3	13	0	0	13
aldehyde dehydrogenase 1 family, member A1	30	0	0	30
EWS/FLI fusion protein	20	0	0	20
aryl hydrocarbon receptor	19	0	0	19
peripheral myelin protein 22	23	0	0	23
cytochrome P450 3A4 isoform 1	19	0	0	19
Gamma-aminobutyric acid receptor subunit pi	19	0	1	20
ATP-binding cassette sub-family C member 3	0	34	0	34
Multidrug resistance-associated protein 4	0	34	0	34
Solute carrier family 22 member 6	0	6	0	8
Carbonic anhydrase 12	0	9	0	15
UDP-glucuronosyltransferase 1A9	0	0	0	2
Bile salt export pump	0	11	0	11
Bile salt export pump	0	49	0	49
Cytochrome P450 2B1	0	0	0	1
Cytochrome P450 1A1	0	0	0	1
Carbonic anhydrase 1	0	18	0	29
Carbonic anhydrase 2	0	19	0	31
Myoglobin	0	1	0	1
Cytochrome P450 1A1	0	0	1	2
Cytochrome P450 1A2	0	5	0	8
Prostaglandin G/H synthase 1	0	7	0	7
Carbonic anhydrase 3	0	9	0	13
Cytochrome P450 3A4	0	16	0	21
Cytochrome P450 2D6	0	10	0	10
Cytochrome P450 2C9	0	23	1	26
Polyunsaturated fatty acid lipoxygenase ALOX15	0	4	0	4
Gamma-aminobutyric acid receptor subunit beta-1	19	0	1	20
Sulfotransferase 1A1	0	0	0	1
Gamma-aminobutyric acid receptor subunit delta	19	0	1	20
Gamma-aminobutyric acid receptor subunit gamma-2	19	0	1	20
UDP-glucuronosyltransferase 1-6	0	2	0	3
Gamma-aminobutyric acid receptor subunit alpha-5	19	0	1	20
Gamma-aminobutyric acid receptor subunit alpha-3	19	0	1	20
Arachidonate 5-lipoxygenase-activating protein	0	1	0	1
UDP-glucuronosyltransferase 1A1	0	4	0	6
Carbonic anhydrase 4	0	13	0	18
Prostaglandin G/H synthase 1	0	7	0	8
Carbonic anhydrase 6	0	11	0	16
Gamma-aminobutyric acid receptor subunit gamma-1	19	0	1	20
Gamma-aminobutyric acid receptor subunit alpha-2	19	0	1	20
Gamma-aminobutyric acid receptor subunit alpha-4	19	0	1	20
Gamma-aminobutyric acid receptor subunit gamma-3	19	0	1	20
Gamma-aminobutyric acid receptor subunit alpha-6	19	0	1	20
Carbonic anhydrase 5A, mitochondrial	0	10	0	15
Prostaglandin G/H synthase 2	0	10	1	13
Carbonic anhydrase 7	0	9	0	14
Nuclear receptor ROR-gamma	13	0	0	13
Cytochrome P450 2J2	0	11	0	11
Gamma-aminobutyric acid receptor subunit alpha-1	19	3	1	23
Gamma-aminobutyric acid receptor subunit beta-3	19	0	1	20
Gamma-aminobutyric acid receptor subunit beta-2	19	0	1	20
Carbonic anhydrase 9	0	11	0	18
GABA theta subunit	19	0	1	20
Canalicular multispecific organic anion transporter 1	0	31	0	31
Carbonic anhydrase 15	0	8	0	12
Carbonic anhydrase 13	0	7	0	11
Gamma-aminobutyric acid receptor subunit epsilon	19	0	1	20
Carbonic anhydrase 14	0	9	0	14
Carbonic anhydrase 5B, mitochondrial	0	9	0	14
toxin B	0	0	0	1
Fibrinogen C domain-containing protein 1	0	1	0	1
Putative glycosyltransferase WbgO	0	0	0	1
Cannabinoid receptor 1	0	1	0	1
Killer cell lectin-like receptor subfamily B member 1A	0	1	0	1
Early activation antigen CD69	0	1	0	1
Chain A, JmjC domain-containing histone demethylation protein 3A	6	0	0	6
USP1 protein, partial	21	0	0	21
TDP1 protein	46	0	0	46
vitamin D3 receptor isoform VDRA	18	0	0	18
flap endonuclease 1	12	0	0	12
serine/threonine-protein kinase PLK1	6	0	0	6
eyes absent homolog 2 isoform a	1	0	0	1
DNA polymerase eta isoform 1	5	0	0	5
histone acetyltransferase KAT2A isoform 1	15	0	0	15
Rap guanine nucleotide exchange factor 3	13	0	0	13
Rap guanine nucleotide exchange factor 4	5	0	0	5
Chain E, Purine nucleoside phosphorylase	0	1	0	1
Chain A, HADH2 protein	16	0	0	16
Chain B, HADH2 protein	16	0	0	16
Chain A, ATP-DEPENDENT DNA HELICASE Q1	7	0	0	7
Chain A, Ferritin light chain	11	0	0	11
Thymidine kinase	0	1	0	1
thioredoxin reductase	21	0	0	21
phosphopantetheinyl transferase	15	0	0	15
arylsulfatase A	10	0	0	10
Bloom syndrome protein isoform 1	12	0	0	12
hemoglobin subunit beta	3	0	0	3
atrial natriuretic peptide receptor 1 precursor	3	0	0	3
ubiquitin carboxyl-terminal hydrolase 2 isoform a	3	0	0	3
lamin isoform A-delta10	41	0	0	41
Solute carrier family 22 member 1	0	4	0	6
Purine nucleoside phosphorylase	0	3	0	3
Thymidine kinase, cytosolic	0	2	0	4
POU domain, class 2, transcription factor 2	0	0	0	1
Disintegrin and metalloproteinase domain-containing protein 17	2	1	0	3
Purine nucleoside phosphorylase	0	0	1	1
Solute carrier family 22 member 6	0	4	0	7
Thymidine kinase	0	1	0	1
Solute carrier family 22 member 8	0	4	0	6
Thymidine kinase	0	1	0	1
Chain A, MTA/SAH nucleosidase	0	1	0	1
Chain A, Ribosome-inactivating protein alpha-trichosanthin	0	0	1	1
Chain A, Ricin A chain	0	0	1	1
Chain A, Ribosome-inactivating protein 3	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
cytochrome P450 family 3 subfamily A polypeptide 4	33	0	0	33
nuclear factor erythroid 2-related factor 2 isoform 2	10	0	0	10
importin subunit beta-1 isoform 1	5	0	0	5
snurportin-1	5	0	0	5
tumor susceptibility gene 101 protein	1	0	0	1
GTP-binding nuclear protein Ran isoform 1	1	0	0	1
Cyclin-dependent kinase 1	0	1	1	2
Heat shock protein HSP 90-beta	0	2	1	4
Xanthine dehydrogenase/oxidase	0	1	0	1
TAR DNA-binding protein 43	9	0	0	9
Protein mono-ADP-ribosyltransferase PARP15	0	1	0	1
Leucine-rich repeat serine/threonine-protein kinase 2	0	2	0	2
Chain A, Heat Shock Protein 90	0	0	1	1
Chain A, GLUTAMINE PHOSPHORIBOSYLPYROPHOSPHATE AMIDOTRANSFERASE	0	0	1	1
Chain B, GLUTAMINE PHOSPHORIBOSYLPYROPHOSPHATE AMIDOTRANSFERASE	0	0	1	1
Chain A, EOSINOPHIL-DERIVED NEUROTOXIN	0	1	0	1
Chain A, EOSINOPHIL-DERIVED NEUROTOXIN	0	1	0	1
Chain A, EOSINOPHIL-DERIVED NEUROTOXIN	0	1	0	1
Chain A, Myosin Ie Heavy Chain	0	0	1	1
Chain A, Preprotein translocase secA	0	0	1	1
Chain A, Ribonuclease pancreatic	0	1	0	1
Chain A, Ribonuclease pancreatic	0	1	0	1
Chain A, Ribonuclease pancreatic	0	1	0	1
Chain A, Ribonuclease pancreatic	0	1	0	1
Chain A, Ribonuclease pancreatic	0	1	0	1
Chain A, Phosphoribosylformylglycinamidine synthase	0	1	0	1
Chain A, nucleoside diphosphate kinase A	0	0	1	1
Chain B, nucleoside diphosphate kinase A	0	0	1	1
Chain D, DNA polymerase III subunit gamma	0	0	1	1
Chain D, DNA polymerase III subunit gamma	0	0	1	1
Chain A [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 3	0	0	1	1
Chain A [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 3	0	0	1	1
Chain A, Kinesin-like protein KIF11	0	1	0	1
HPr kinase/phosphorylase	0	0	1	1
Mitogen-activated protein kinase kinase kinase 7	0	0	1	1
ATP-dependent molecular chaperone HSP82	0	0	0	1
Heat shock protein HSP 90-alpha	0	1	1	3
2-dehydropantoate 2-reductase	0	1	1	2
Heat shock 70 kDa protein 1A	0	1	1	2
Endoplasmic reticulum chaperone BiP	0	0	1	1
Heat shock cognate 71 kDa protein	0	0	1	1
Pyruvate kinase PKM	0	0	0	1
Pyruvate kinase PKLR	0	0	0	1
Endoplasmin	0	0	0	1
Heat shock cognate 71 kDa protein	0	0	1	1
5'-nucleotidase	0	2	0	2
Mu-type opioid receptor	0	7	2	9
Delta-type opioid receptor	0	2	1	3
Kappa-type opioid receptor	0	6	1	7
Endoplasmin	0	1	1	2
P2Y purinoceptor 2	0	0	2	2
Phosphatidylinositol 4-kinase alpha	0	2	0	2
P2X purinoceptor 1	0	0	1	1
P2Y purinoceptor 1	0	0	1	1
P2Y purinoceptor 1	0	0	1	1
P2X purinoceptor 1	0	0	1	1
P2X purinoceptor 4	0	0	1	1
P2X purinoceptor 5	0	0	1	1
P2X purinoceptor 6	0	0	1	1
P2X purinoceptor 3	0	0	1	1
Inositol monophosphatase 1	6	0	0	6
Heat shock protein 75 kDa, mitochondrial	0	1	0	1
P2Y purinoceptor 6	0	0	1	1
Phosphatidylinositol 4-kinase type 2-beta	0	2	0	2
P2Y purinoceptor 11	0	0	1	1
Phosphatidylinositol 4-kinase type 2-alpha	0	2	0	2
P2Y purinoceptor 12	0	1	1	2
Sensor protein kinase WalK	0	1	0	1
Phosphatidylinositol 4-kinase beta	0	2	0	2
P2X purinoceptor 2	0	0	1	1
Chain A, TYROSYL-DNA PHOSPHODIESTERASE	19	0	0	19
Alanine racemase, biosynthetic	0	0	0	1
5-hydroxytryptamine receptor 1D	0	0	0	2
Glutamate receptor ionotropic, NMDA 1	0	7	2	13
Proton-coupled amino acid transporter 1	0	6	0	7
Adenosine deaminase	0	0	0	1
Carbonic anhydrase 4	0	2	0	4
Aminoglycoside 3'-phosphotransferase	0	0	0	1
ATP-dependent phosphofructokinase	14	0	0	14
Chain A, PLASMINOGEN	0	0	2	2
Chain A, PLASMINOGEN	0	0	2	2
Chain A, Apolipoprotein	0	0	1	1
15-lipoxygenase, partial	10	0	0	10
nonstructural protein 1	5	0	0	5
D(1A) dopamine receptor	2	0	0	2
thyroid hormone receptor beta isoform a	14	0	0	14
peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	6	0	0	6
Plasminogen	0	4	2	6
Lysyl oxidase homolog 2	0	1	0	1
Protein-lysine 6-oxidase	0	1	0	1
Protein-lysine 6-oxidase	0	1	0	1
Lysyl oxidase homolog 2	0	1	0	1
Lysyl oxidase homolog 3	0	1	0	1
Lysyl oxidase homolog 4	0	1	0	1
Lysyl oxidase homolog 2	0	1	0	1
30S ribosomal protein S6	0	2	1	3
30S ribosomal protein S7	0	2	1	3
50S ribosomal protein L15	0	2	1	3
50S ribosomal protein L10	0	2	1	3
50S ribosomal protein L11	0	2	1	3
50S ribosomal protein L7/L12	0	2	1	3
50S ribosomal protein L19	0	2	1	3
50S ribosomal protein L1	0	2	1	3
50S ribosomal protein L20	0	2	1	3
50S ribosomal protein L27	0	2	1	3
50S ribosomal protein L28	0	2	1	3
50S ribosomal protein L29	0	2	1	3
50S ribosomal protein L31	0	2	1	3
50S ribosomal protein L31 type B	0	2	1	3
50S ribosomal protein L32	0	2	1	3
50S ribosomal protein L33	0	2	1	3
50S ribosomal protein L34	0	2	1	3
50S ribosomal protein L35	0	2	1	3
50S ribosomal protein L36	0	2	1	3
30S ribosomal protein S10	0	2	1	3
30S ribosomal protein S11	0	2	1	3
30S ribosomal protein S12	0	2	1	3
30S ribosomal protein S13	0	2	1	3
30S ribosomal protein S16	0	2	1	3
30S ribosomal protein S18	0	2	1	3
30S ribosomal protein S19	0	2	1	3
30S ribosomal protein S20	0	2	1	3
30S ribosomal protein S2	0	2	1	3
30S ribosomal protein S3	0	2	1	3
30S ribosomal protein S4	0	2	1	3
30S ribosomal protein S5	0	2	1	3
30S ribosomal protein S8	0	2	1	3
30S ribosomal protein S9	0	2	1	3
50S ribosomal protein L13	0	2	1	3
50S ribosomal protein L14	0	2	1	3
50S ribosomal protein L16	0	2	1	3
50S ribosomal protein L23	0	2	1	3
30S ribosomal protein S15	0	2	1	3
50S ribosomal protein L17	0	2	1	3
50S ribosomal protein L21	0	2	1	3
50S ribosomal protein L30	0	2	1	3
50S ribosomal protein L6	0	2	1	3
30S ribosomal protein S14	0	2	1	3
30S ribosomal protein S17	0	2	1	3
30S ribosomal protein S1	0	2	1	3
50S ribosomal protein L18	0	2	1	3
50S ribosomal protein L2	0	2	1	3
50S ribosomal protein L3	0	2	1	3
50S ribosomal protein L24	0	2	1	3
50S ribosomal protein L4	0	2	1	3
50S ribosomal protein L22	0	2	1	3
50S ribosomal protein L5	0	2	1	3
30S ribosomal protein S21	0	2	1	3
50S ribosomal protein L25	0	2	1	3
50S ribosomal protein L36 2	0	2	1	3
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	2	2
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	2	2
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	2	2
NFKB1 protein, partial	6	0	0	6
alpha-galactosidase	4	0	0	4
cytochrome P450 2C19 precursor	5	0	0	5
DNA polymerase iota isoform a (long)	15	0	0	15
lethal factor (plasmid)	11	0	0	11
Nitric oxide synthase, endothelial	0	0	0	2
Nitric oxide synthase, brain	0	0	0	1
Nitric oxide synthase, brain	0	0	0	1
Nitric oxide synthase, inducible	0	1	0	2
Nitric oxide synthase, inducible	0	0	1	3
Cationic amino acid transporter 3	0	2	0	2
Translocator protein	0	0	1	1
Vasopressin V2 receptor	0	4	3	8
Oxytocin receptor	0	3	4	7
Vasopressin V1a receptor	0	1	2	3
Vasopressin V1a receptor	0	6	3	9
Vasopressin V1b receptor	0	3	3	6
Vasopressin V2 receptor	0	0	1	1
Vasopressin V1b receptor	0	2	1	4
Translocator protein	0	2	0	3
Oxytocin receptor	0	2	0	2
Vasopressin V2 receptor	0	3	2	5
Neutral amino acid transporter A	0	3	0	3
Neutral amino acid transporter B(0)	0	3	0	3
Carbonic anhydrase-like protein, putative	0	0	0	7
Amino acid transporter	0	3	0	3
Chain A, Phospholipase A2 isoform 3	0	0	1	1
Chain A, 2-oxoglutarate Oxygenase	13	0	0	13
GTP-binding protein (rab7)	0	0	2	2
ras protein, partial	0	0	2	2
interleukin 8	9	0	0	9
hypothetical protein, conserved	2	0	0	2
cytochrome P450 2D6	18	0	0	18
glucocerebrosidase	4	0	0	4
Rac1 protein	0	0	2	2
IDH1	12	0	0	12
cell division cycle 42 (GTP binding protein, 25kDa), partial	0	0	2	2
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1	10	0	0	10
DNA polymerase kappa isoform 1	13	0	0	13
Prostaglandin-H2 D-isomerase	0	1	0	1
Prostaglandin G/H synthase 1	0	3	0	3
Prostaglandin G/H synthase 2	0	4	0	4
Epidermal growth factor receptor	0	8	2	10
Fatty acid-binding protein, liver	0	3	0	3
Integrin beta-3	7	1	1	9
Myeloperoxidase	0	2	0	2
Seed linoleate 13S-lipoxygenase-1	0	3	0	3
Integrin alpha-IIb	7	1	1	9
Glutathione hydrolase 1 proenzyme	0	1	0	1
Adenosine receptor A1	0	6	0	9
Adenosine receptor A2a	0	5	0	8
Substance-P receptor	0	3	0	4
Urotensin-2 receptor	0	2	0	2
4-aminobutyrate aminotransferase, mitochondrial	0	2	0	2
Ras-related protein Rab-2A	0	0	2	2
Prostaglandin G/H synthase 2	0	6	0	6
Rho-associated protein kinase 2	0	1	0	1
Nicotinate phosphoribosyltransferase	0	3	0	3
Solute carrier family 22 member 20	0	3	0	3
Solute carrier family 22 member 6	0	3	0	3
Sigma non-opioid intracellular receptor 1	0	1	1	2
Sigma non-opioid intracellular receptor 1	0	0	1	1
Fumarate hydratase	8	0	0	8
thioredoxin glutathione reductase	10	0	0	10
polyprotein	8	0	0	8
P53	1	0	0	1
peripheral myelin protein 22 isoform 1	8	0	0	8
cellular tumor antigen p53 isoform a	10	0	0	10
M-phase phosphoprotein 8	5	0	0	5
Protein-arginine deiminase type-4	0	1	0	1
Chain A, Putative fructose-1,6-bisphosphate aldolase	5	0	0	5
Chain A, Cruzipain	7	0	0	7
caspase-1 isoform alpha precursor	2	0	0	2
Caspase-7	2	0	0	2
Solute carrier organic anion transporter family member 1B3	0	9	0	12
Solute carrier organic anion transporter family member 1B1	0	11	0	15
Chain H, Proteasome component PUP1	0	1	0	1
Chain I, Proteasome component PUP3	0	1	0	1
Chain K, Proteasome component PRE2	0	1	0	1
Chain L, Proteasome component C5	0	1	0	1
Chain K, Proteasome component PRE2	0	1	0	1
Chain L, Proteasome component C5	0	1	0	1
Proteasome subunit beta type-11	0	1	0	1
PPM1D protein	7	0	0	7
nuclear receptor subfamily 1, group I, member 2	7	0	0	7
26S proteasome non-ATPase regulatory subunit 11	0	1	0	1
26S proteasome non-ATPase regulatory subunit 12	0	1	0	1
26S proteasome non-ATPase regulatory subunit 14	0	1	0	1
Proteasome subunit alpha type-7	0	1	0	1
26S proteasome non-ATPase regulatory subunit 3	0	1	0	1
Prothrombin	0	1	2	3
Chymotrypsinogen A	0	2	0	2
Cathepsin B	0	1	0	1
Neutrophil elastase	0	1	0	1
Cathepsin G	0	2	0	2
Lysosomal protective protein	0	2	0	2
Chymotrypsinogen B	0	1	0	1
26S proteasome regulatory subunit 6A	0	1	0	1
Nuclear factor NF-kappa-B p105 subunit	0	1	0	1
Proteasome subunit beta type-1	0	1	0	2
Chymase	0	1	0	1
Proteasome subunit alpha type-1	0	1	0	1
Proteasome subunit alpha type-2	0	1	0	1
Proteasome subunit alpha type-3	0	1	0	1
Proteasome subunit alpha type-4	0	1	0	1
Proteasome subunit beta type-8	0	1	0	1
Proteasome subunit beta type-8	0	1	0	1
Proteasome subunit beta type-9	0	1	0	1
Proteasome subunit alpha type-5	0	1	0	1
Proteasome subunit beta type-4	0	1	0	1
Proteasome subunit beta type-6	0	1	0	1
Proteasome subunit beta type-5	0	3	0	4
26S proteasome regulatory subunit 7	0	1	0	1
Lon protease homolog, mitochondrial	0	1	0	1
Proteasome subunit beta type-10	0	1	0	1
26S proteasome regulatory subunit 6B	0	1	1	2
26S proteasome non-ATPase regulatory subunit 8	0	1	0	1
Proteasome subunit beta type-3	0	1	0	1
Proteasome subunit beta type-2	0	1	0	2
26S proteasome non-ATPase regulatory subunit 7	0	1	0	1
26S proteasome non-ATPase regulatory subunit 4	0	1	0	1
26S proteasome complex subunit SEM1	0	1	0	1
Proteasome subunit alpha type-6	0	1	0	1
26S proteasome regulatory subunit 4	0	1	0	1
26S proteasome regulatory subunit 8	0	1	0	1
26S proteasome regulatory subunit 10B	0	1	0	1
Beta-carbonic anhydrase 1	0	2	0	2
Nuclear factor NF-kappa-B p100 subunit	0	1	0	1
Transcription factor p65	0	1	0	1
26S proteasome non-ATPase regulatory subunit 2	0	1	0	1
26S proteasome non-ATPase regulatory subunit 6	0	1	0	1
Proteasomal ubiquitin receptor ADRM1	0	1	0	1
ATP-dependent Clp protease proteolytic subunit	0	1	1	2
Carbonic anhydrase 13	0	4	0	6
NACHT, LRR and PYD domains-containing protein 3	0	1	0	1
Proteasome subunit alpha-type 8	0	1	0	1
Proteasome subunit beta type-7	0	1	0	1
26S proteasome non-ATPase regulatory subunit 1	0	1	0	1
26S proteasome non-ATPase regulatory subunit 13	0	1	0	1
Angiotensin-converting enzyme	0	3	0	4
B2 bradykinin receptor	0	1	0	1
B2 bradykinin receptor	0	2	1	5
B1 bradykinin receptor	0	1	0	1
Olfactory receptor 51E2	0	0	3	3
apical membrane antigen 1, AMA1	5	0	0	5
Matrix metalloproteinase-9	0	2	0	2
Chain A, Vitamin D Nuclear Receptor	0	0	1	1
Chain A, Beta-lactamase	12	0	0	12
Vitamin D3 receptor	0	0	1	1
nuclear receptor ROR-gamma isoform 1	9	0	0	9
Vitamin D-binding protein	0	0	1	1
Androgen receptor	0	4	0	4
Vitamin D3 receptor	0	1	2	4
Vitamin D3 receptor	0	1	1	3
Retinoic acid receptor RXR-alpha	0	0	3	3
Cytochrome P450 2C19	0	5	0	6
Kappa-type opioid receptor	0	0	1	1
Vitamin D3 receptor	0	0	1	1
1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial	0	0	1	1
Vitamin D3 receptor	0	1	1	2
Transporter	0	1	0	1
Vitamin D3 receptor A	0	0	2	2
Liver carboxylesterase 1	0	0	0	2
Chain A, Neutrophil gelatinase-associated lipocalin	0	0	1	1
endonuclease IV	5	0	0	5
Nrf2	1	0	0	1
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	7	0	0	7
Parkin	2	0	0	2
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)	4	0	0	4
NPC intracellular cholesterol transporter 1 precursor	2	0	0	2
DNA polymerase beta	2	0	0	2
ras-related protein Rab-9A	3	0	0	3
serine/threonine-protein kinase mTOR isoform 1	2	0	0	2
urokinase-type plasminogen activator precursor	7	0	0	7
plasminogen precursor	7	0	0	7
urokinase plasminogen activator surface receptor precursor	7	0	0	7
lethal(3)malignant brain tumor-like protein 1 isoform I	1	0	0	1
DNA dC->dU-editing enzyme APOBEC-3G isoform 1	2	1	0	3
Polyunsaturated fatty acid lipoxygenase ALOX15B	5	0	0	5
Tyrosine-protein kinase Fyn	0	3	1	4
3-dehydroquinate synthase	0	1	0	2
Prolyl 4-hydroxylase subunit alpha-1	0	4	0	4
Potassium-transporting ATPase subunit beta	0	0	0	1
Potassium-transporting ATPase alpha chain 1	0	0	0	1
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	0	1	0	1
Histamine H2 receptor	8	0	0	9
D(1A) dopamine receptor	1	0	0	1
Autoinducer 2-binding periplasmic protein LuxP	0	3	0	3
E3 ubiquitin-protein ligase Mdm2	0	1	0	1
Glutaminyl-peptide cyclotransferase	0	2	0	2
Arginase-1	0	1	0	1
Carbonic anhydrase	0	4	0	4
Carbonic anhydrase 3	0	2	0	2
phosphoglycerate kinase	2	0	0	2
Chain A, Carbonic anhydrase II	0	1	0	1
Carbonic anhydrase	0	0	0	1
Carbonic anhydrase	0	1	0	1
glp-1 receptor, partial	11	0	0	11
pregnane X receptor	9	0	0	9
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase	0	1	0	1
67.9K protein	11	0	0	11
Carbonic anhydrase	0	1	0	1
interferon gamma precursor	0	0	0	1
prostaglandin E2 receptor EP2 subtype	0	0	0	1
potassium voltage-gated channel subfamily H member 2 isoform d	8	0	0	8
Prostaglandin E synthase	0	1	0	1
3-phosphoinositide-dependent protein kinase 1	0	1	0	1
cGMP-specific 3',5'-cyclic phosphodiesterase	0	1	0	1
Cytochrome c oxidase subunit 1	0	1	0	1
Cytochrome c oxidase subunit 2	0	1	0	1
Catechol O-methyltransferase	0	1	0	1
Cytochrome c oxidase subunit 2	0	2	0	2
Procathepsin L	0	2	2	4
Aldo-keto reductase family 1 member B1	0	10	0	10
Neuronal acetylcholine receptor subunit alpha-4	1	2	0	3
Polyunsaturated fatty acid 5-lipoxygenase	0	2	0	2
Quinolone resistance protein NorA	0	1	0	1
Adenosine receptor A3	0	7	0	7
Neuronal acetylcholine receptor subunit beta-2	1	2	0	3
Beta-3 adrenergic receptor	0	4	0	4
Alpha-1B adrenergic receptor	0	9	0	9
Calpain-2 catalytic subunit	0	2	0	2
Alpha-2B adrenergic receptor	0	5	0	5
5-hydroxytryptamine receptor 1A	0	1	0	1
D(1A) dopamine receptor	0	4	0	4
Prostaglandin G/H synthase 1	0	3	0	3
Sodium-dependent noradrenaline transporter	0	10	0	10
Cruzipain	0	2	0	2
Sodium/hydrogen exchanger 1	0	1	0	1
Indoleamine 2,3-dioxygenase 1	0	1	0	1
Sodium-dependent serotonin transporter	0	8	0	8
Sodium-dependent serotonin transporter	0	3	1	4
Delta-type opioid receptor	0	2	0	2
Delta-type opioid receptor	0	1	0	1
Mu-type opioid receptor	0	1	0	1
Bifunctional epoxide hydrolase 2	0	4	0	4
Prostaglandin G/H synthase 2	0	4	0	5
Carbonic anhydrase	0	3	0	7
Alpha-1A adrenergic receptor	0	9	0	9
Carbonic anhydrase	0	1	0	5
D(2) dopamine receptor	0	1	0	1
Carbonic anhydrase	0	1	0	1
Mu-type opioid receptor	0	5	0	5
Carbonic anhydrase 2	0	1	0	1
Sodium-dependent dopamine transporter	0	4	0	4
Prostaglandin G/H synthase 2	0	3	0	3
Mitogen-activated protein kinase 14	0	1	1	2
Carbonic anhydrase, alpha family	0	1	0	1
Carbonic anhydrase	0	1	0	5
Carbonic anhydrase	0	1	0	5
Carbonic anhydrase	0	1	0	5
Carbonic anhydrase	0	1	0	1
Sigma intracellular receptor 2	0	2	0	2
Delta carbonic anhydrase	0	1	0	1
Prostaglandin G/H synthase 1	0	4	0	5
Carbonic anhydrase	0	1	0	5
Prostaglandin G/H synthase 1	0	1	0	1
Cyclooxygenase-2	0	2	0	2
Caspase-2	0	0	1	1
glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase	0	1	0	1
Spike glycoprotein	0	1	2	3
Replicase polyprotein 1ab	0	1	2	3
glucose-6-phosphate 1-dehydrogenase isoform b	0	1	0	1
Transmembrane protease serine 2	0	1	2	3
Dihydrofolate reductase	0	2	0	2
DNA ligase	0	1	0	1
Riboflavin-binding protein	0	0	1	1
Major prion protein	0	0	1	1
Amyloid-beta precursor protein	0	3	0	3
Histidine-rich protein PFHRP-II	0	1	0	2
Muscarinic acetylcholine receptor M2	0	5	0	5
Muscarinic acetylcholine receptor M4	0	3	0	3
Muscarinic acetylcholine receptor M5	0	3	0	3
Alpha-2A adrenergic receptor	0	4	0	4
Replicase polyprotein 1a	0	1	2	3
Replicase polyprotein 1ab	0	1	2	3
Replicase polyprotein 1ab	0	2	2	4
Spike glycoprotein	0	1	0	1
Replicase polyprotein 1ab	0	3	2	5
Muscarinic acetylcholine receptor M1	0	3	0	3
Ribosyldihydronicotinamide dehydrogenase [quinone]	0	1	1	2
Alpha-2C adrenergic receptor	0	3	0	3
DNA ligase 1	0	1	0	1
Muscarinic acetylcholine receptor M3	0	5	0	5
Serine/threonine-protein kinase mTOR	0	2	0	2
Nuclear receptor subfamily 4 group A member 2	0	0	1	1
Beta-secretase 1	0	3	0	3
Spike glycoprotein	15	1	2	18
Calcium-dependent protein kinase 1	0	0	1	1
MO15-related protein kinase Pfmrk	0	1	0	1
DNA ligase A	0	1	0	1
Potassium voltage-gated channel subfamily H member 2	0	11	0	11
Sigma intracellular receptor 2	0	1	0	1
Phosphoethanolamine N-methyltransferase	0	1	0	1
Angiotensin-converting enzyme 2	0	1	2	3
Cysteine proteinase falcipain 2a	0	1	0	1
Cysteine proteinase falcipain 2a	0	1	0	1
atrial natriuretic peptide receptor 2 precursor	2	0	0	2
Histamine H1 receptor	0	4	0	4
MBT domain-containing protein 1	0	1	0	1
Solute carrier family 22 member 1	0	4	0	5
Lethal(3)malignant brain tumor-like protein 4	0	1	0	1
Lethal(3)malignant brain tumor-like protein 3	0	1	0	1
Chloroquine resistance transporter	0	1	0	1
Solute carrier family 22 member 2	0	3	0	4
Lethal(3)malignant brain tumor-like protein 1	0	1	0	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Putative Glycine Betaine-binding Abc Transporter Protein	0	0	1	1
Chain A, PUTATIVE GLYCINE BETAINE-BINDING ABC TRANSPORTER PROTEIN	0	0	1	1
Chain A, Glycine betaine/carnitine/choline-binding protein	0	0	1	1
Chain A, Glycine betaine/carnitine/choline-binding protein	0	0	1	1
Chain A, Glycine betaine/carnitine/choline-binding protein	0	0	1	1
Chain A, Glycine betaine/carnitine/choline-binding protein	0	0	1	1
Chain A, Choline-binding protein	0	0	1	1
Solute carrier family 22 member 1	0	2	0	3
Solute carrier family 22 member 2	0	2	0	3
Solute carrier family 22 member 2	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-3	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-2	0	1	0	1
Neuronal acetylcholine receptor subunit beta-3	0	1	0	1
Neuronal acetylcholine receptor subunit beta-4	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-5	0	1	0	1
Acetylcholinesterase	0	7	1	8
Sodium- and chloride-dependent creatine transporter 1	0	1	0	1
Choline O-acetyltransferase	0	0	0	1
Neuronal acetylcholine receptor subunit alpha-6	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-9	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-7	0	1	0	1
High affinity choline transporter 1	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-10	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, N5-carboxyaminoimidazole ribonucleotide mutase	0	0	1	1
Chain B, N5-carboxyaminoimidazole ribonucleotide mutase	0	0	1	1
Chain A, N5-carboxyaminoimidazole ribonucleotide mutase	0	0	1	1
Chain B, N5-carboxyaminoimidazole ribonucleotide mutase	0	0	1	1
hepatocyte nuclear factor 4-alpha isoform 2	0	1	0	1
perilipin-5	0	1	0	1
perilipin-1	0	1	0	1
1-acylglycerol-3-phosphate O-acyltransferase ABHD5 isoform a	0	1	0	1
Beta-lactamase	0	1	0	1
Proto-oncogene tyrosine-protein kinase Src	0	3	1	4
3-dehydroquinate dehydratase	0	0	1	1
ATP-citrate synthase	0	1	0	2
Ribonuclease T	0	0	0	1
Cell death-related nuclease 4	0	0	0	1
3-dehydroquinate dehydratase	0	0	1	1
Prolyl 4-hydroxylase	0	2	0	2
Alpha-ketoglutarate-dependent dioxygenase FTO	0	2	0	2
PAX8	0	0	0	2
cytochrome P450 2D6 isoform 1	3	0	0	3
nuclear receptor subfamily 0 group B member 1	0	1	0	1
cytochrome P450 2C9 precursor	4	0	0	4
steroidogenic factor 1	0	1	0	1
neuropeptide S receptor isoform A	4	0	0	4
Solute carrier family 22 member 3	0	4	0	4
Tubulin alpha-1A chain	0	2	1	3
Tubulin beta chain	0	2	1	3
Plasma kallikrein	0	0	0	5
Tubulin beta-4A chain	0	2	2	5
ATP-dependent translocase ABCB1	0	5	0	5
Tubulin beta chain	0	2	2	5
ATP-dependent translocase ABCB1	0	7	0	8
Tubulin alpha-3C chain	0	2	2	5
Serine/threonine-protein kinase pim-1	0	1	1	2
ATP-dependent translocase ABCB1	0	5	0	5
Tubulin alpha-1B chain	0	2	2	5
Tubulin alpha-4A chain	0	2	2	5
Tubulin beta-4B chain	0	2	2	5
Vesicular acetylcholine transporter	0	1	0	1
Tubulin beta-3 chain	0	2	2	5
Tubulin beta-2A chain	0	2	2	5
Tubulin polymerization-promoting protein	0	0	1	1
Tubulin beta-8 chain	0	2	2	5
Tubulin beta-2B chain	0	2	0	2
Tubulin alpha-3E chain	0	2	2	5
Tubulin alpha-1A chain	0	2	2	5
Similar to alpha-tubulin isoform 1	0	1	0	1
Similar to alpha-tubulin isoform 1	0	1	0	1
CREB-binding protein	1	0	0	1
Tubulin alpha-1C chain	0	2	2	5
Tubulin beta-6 chain	0	2	2	5
Tubulin beta-2B chain	0	2	2	5
Tubulin beta-1 chain	0	2	2	5
Glucocorticoid receptor	0	10	2	17
Sex hormone-binding globulin	0	0	2	2
Glycine receptor subunit alpha-1	0	10	0	10
Corticosteroid-binding globulin	0	2	0	2
Glycine receptor subunit beta	0	10	0	10
Glycine receptor subunit alpha-2	0	10	0	10
Glycine receptor subunit alpha-3	0	10	0	10
Potassium voltage-gated channel subfamily A member 1	0	0	1	1
Multidrug and toxin extrusion protein 1	0	6	0	6
GALC protein	3	0	0	3
glycogen synthase kinase-3 alpha	0	0	0	1
Exportin-1	0	1	0	1
Glyceraldehyde-3-phosphate dehydrogenase	0	1	0	1
NAD-dependent histone deacetylase SIR2	0	1	0	3
Cytochrome P450 2A6	0	0	0	1
Aldo-keto reductase family 1 member B1	0	3	0	3
UDP-glucuronosyltransferase 2B7	0	2	0	6
Amine oxidase [flavin-containing] B	0	1	0	1
Cytochrome P450 2A5	0	0	0	1
Amine oxidase [flavin-containing] A	0	1	0	1
Acetylcholinesterase	0	1	0	1
UDP-glucuronosyltransferase 1A4	0	2	0	3
Glyceraldehyde-3-phosphate dehydrogenase, glycosomal	0	1	0	1
UDP-glucuronosyltransferase 2B10	0	2	0	2
Quinone oxidoreductase	0	0	0	1
Sorbitol dehydrogenase	0	1	0	1
Induced myeloid leukemia cell differentiation protein Mcl-1	0	2	0	2
Zn finger protein	0	1	0	1
Dihydroorotate dehydrogenase	0	1	0	1
Chain A, Glucose-1-phosphate cytidylyltransferase	0	1	0	1
Chain B, CTP synthase	0	1	0	1
RNA-directed RNA polymerase	0	0	1	3
Glucose-1-phosphate cytidylyltransferase	0	1	0	1
Deoxycytidine kinase	0	0	0	1
Estrogen receptor	0	10	0	10
Androgen receptor	0	9	0	9
Substance-K receptor	0	6	0	6
5-hydroxytryptamine receptor 2A	0	4	0	4
D(3) dopamine receptor	0	3	0	3
Hsf1 protein	0	0	1	1
NAD	0	1	0	1
Cholinesterase	0	2	0	2
Urease	0	1	0	1
NAD	0	1	0	2
Mitogen-activated protein kinase 1	0	1	1	2
ATP phosphoribosyltransferase	0	1	0	1
Proprotein convertase subtilisin/kexin type 7	0	2	0	2
Enoyl-[acyl-carrier-protein] reductase [NADH]	0	1	0	1
Integrase	0	2	0	2
G-protein coupled receptor 35	0	3	3	6
Chain A, DigA16	0	0	1	1
Chain A, DigA16	0	0	1	1
Sodium/potassium-transporting ATPase subunit alpha-1	0	1	0	1
Sodium/potassium-transporting ATPase subunit beta-1	0	1	0	1
Sodium/potassium-transporting ATPase subunit alpha-2	0	1	0	1
Solute carrier organic anion transporter family member 4C1	0	2	0	3
polyunsaturated fatty acid lipoxygenase ALOX12	1	0	0	1
runt-related transcription factor 1 isoform AML1b	3	0	0	3
core-binding factor subunit beta isoform 2	3	0	0	3
Glutamate receptor 1	2	3	1	6
Glutamate receptor 3	2	3	1	6
Glutamate receptor 4	2	3	1	6
huntingtin isoform 2	1	0	0	1
5-hydroxytryptamine receptor 4	0	2	0	2
Angiotensin-converting enzyme	0	2	0	2
5-hydroxytryptamine receptor 2C	0	2	0	2
Histamine H1 receptor	0	0	1	2
5-hydroxytryptamine receptor 2B	0	2	0	2
Histamine N-methyltransferase	0	0	0	1
Sodium channel protein type 5 subunit alpha	0	1	0	1
Nuclear receptor subfamily 3 group C member 3	0	2	0	2
Calcium release-activated calcium channel protein 1	0	1	0	1
Protein orai-2	0	1	0	1
Protein orai-3	0	1	0	1
Histamine H4 receptor	0	2	0	2
Histamine H3 receptor	0	0	0	1
Eyes absent homolog 2	0	1	0	1
Metallo-beta-lactamase VIM-13	0	1	0	1
Beta-lactamase	0	1	0	1
Beta-lactamase	0	1	0	1
Beta-lactamase VIM-1	0	1	0	1
Chain A, Casein kinase II subunit alpha	0	1	0	1
Mcl-1	0	1	0	1
acetyl-CoA acetyltransferase/HMG-CoA reductase	0	1	0	1
bromodomain adjacent to zinc finger domain 2B	3	0	0	3
unnamed protein product	0	2	0	2
heat shock 70kDa protein 1A	0	1	0	1
Aldehyde oxidase 1	0	1	0	1
serine-protein kinase ATM isoform a	1	0	0	1
lysosomal alpha-glucosidase preproprotein	2	0	0	2
fructose-bisphosphate aldolase A	2	0	0	2
glyceraldehyde-3-phosphate dehydrogenase isoform 1	2	0	0	2
dual specificity protein phosphatase 3	0	2	0	2
eukaryotic translation initiation factor 4 gamma 1 isoform 4	0	1	0	1
mothers against decapentaplegic homolog 3 isoform 1	0	1	0	1
histone-lysine N-methyltransferase 2A isoform 2 precursor	3	0	0	3
heat shock cognate 71 kDa protein isoform 1	0	1	0	1
eukaryotic translation initiation factor 4E isoform 1	0	1	0	1
Vif	0	1	0	1
Tat	0	1	0	1
dual specificity protein phosphatase 6	0	1	0	1
heat shock cognate 71 kDa protein isoform 2	0	1	0	1
Serine/threonine-protein kinase PLK4	0	1	1	2
Inhibitor of nuclear factor kappa-B kinase subunit beta	0	1	0	2
Aurora kinase A	0	1	1	2
Acetylcholinesterase	0	4	0	5
NUAK family SNF1-like kinase 1	0	1	0	1
Glutathione reductase, mitochondrial	0	5	0	5
cAMP-dependent protein kinase catalytic subunit alpha	0	1	0	1
Renin	0	1	0	1
Receptor tyrosine-protein kinase erbB-2	0	2	1	3
Insulin receptor	0	1	1	2
Nucleophosmin	0	1	0	1
Proto-oncogene tyrosine-protein kinase receptor Ret	0	2	1	3
Insulin-like growth factor 1 receptor	0	1	1	2
Muscarinic acetylcholine receptor M1	0	1	0	1
Muscarinic acetylcholine receptor M3	0	1	0	1
Muscarinic acetylcholine receptor M4	0	1	0	1
Hepatocyte growth factor receptor	0	1	1	2
Muscarinic acetylcholine receptor M5	0	1	0	1
Glutathione S-transferase P	0	1	0	1
Platelet-derived growth factor receptor beta	0	2	1	3
Glutathione S-transferase Mu 1	0	1	0	1
Muscarinic acetylcholine receptor M2	0	1	0	1
Cyclin-dependent kinase 4	0	1	1	2
Macrophage migration inhibitory factor	0	2	0	2
Serine/threonine-protein kinase B-raf	0	1	1	2
cAMP-dependent protein kinase catalytic subunit alpha	0	1	1	2
Casein kinase II subunit alpha	0	1	0	1
Casein kinase II subunit alpha'	0	1	1	2
Cyclin-A2	0	1	0	1
Amine oxidase [flavin-containing] A	0	0	1	1
5'-nucleotidase	0	1	0	1
cAMP-dependent protein kinase catalytic subunit gamma	0	1	1	2
cAMP-dependent protein kinase catalytic subunit beta	0	1	1	2
G1/S-specific cyclin-D1	0	1	0	1
Cyclin-dependent kinase 2	0	2	1	3
RAC-alpha serine/threonine-protein kinase	0	1	1	2
Vascular endothelial growth factor receptor 3	0	1	0	1
Vascular endothelial growth factor receptor 2	0	1	0	1
Receptor-type tyrosine-protein kinase FLT3	0	3	1	4
Mitogen-activated protein kinase kinase kinase 8	0	1	0	1
Glycogen synthase kinase-3 beta	0	2	1	3
Squalene monooxygenase	0	2	0	2
Serine/threonine-protein kinase PLK1	0	1	1	2
Ephrin type-B receptor 4	0	1	1	2
Ectonucleoside triphosphate diphosphohydrolase 1	0	1	0	1
Casein kinase II subunit beta	0	1	0	1
Casein kinase II subunit beta	0	1	0	1
Casein kinase II subunit alpha	0	2	0	2
Cyclin-A1	0	1	0	1
Lactoperoxidase	0	0	0	2
Cholinesterase	0	2	0	3
DNA primase	0	1	0	1
Angiopoietin-1 receptor	0	1	0	1
Focal adhesion kinase 1	0	1	1	2
Tyrosine-protein kinase Lyn	0	1	0	1
Polypeptide N-acetylgalactosaminyltransferase 2	0	2	2	4
Dual specificity tyrosine-phosphorylation-regulated kinase 1A	0	1	1	2
ELAV-like protein 3	0	1	0	1
Thioredoxin reductase 1, cytoplasmic	0	1	0	1
5'-nucleotidase	0	1	0	1
Tyrosine-protein kinase Fgr	0	1	0	1
Thioredoxin reductase 3	0	1	0	1
Glutathione S-transferase	0	1	0	1
Aurora kinase B	0	1	1	2
Translin-associated protein X	0	1	0	1
Thioredoxin reductase 2, mitochondrial	0	1	0	1
ALK tyrosine kinase receptor	0	1	0	1
DNA polymerase iota	0	1	0	1
DNA polymerase eta	0	1	0	1
Cysteine protease ATG4B	0	1	0	1
M17 leucyl aminopeptidase	0	1	0	1
likely tRNA 2'-phosphotransferase	0	2	0	2
Motilin receptor	0	0	1	1
acid sphingomyelinase	1	0	0	1
low molecular weight phosphotyrosine protein phosphatase isoform c	0	2	0	2
streptokinase A precursor	0	0	2	2
Motilin receptor	0	1	1	2
Albumin	0	3	6	14
60 kDa chaperonin	0	1	0	1
60 kDa heat shock protein, mitochondrial	0	3	0	3
Chitinase B	0	1	0	1
Low molecular weight phosphotyrosine protein phosphatase	0	2	0	2
10 kDa heat shock protein, mitochondrial	0	3	0	3
Cytochrome P450 1B1	0	1	0	1
Thiosulfate sulfurtransferase	0	3	0	3
Lanosterol 14-alpha demethylase	0	4	1	5
60 kDa chaperonin	0	3	0	3
10 kDa chaperonin	0	3	0	3
Chain A, BCL-2-RELATED PROTEIN A1	0	0	1	1
transcriptional regulator ERG isoform 3	2	0	0	2
heat shock protein HSP 90-alpha isoform 2	0	0	0	2
bcl-2-like protein 11 isoform 1	0	0	1	1
Beta-lactamase	0	1	0	1
Steroid 17-alpha-hydroxylase/17,20 lyase	0	1	0	1
Heme oxygenase 1	0	1	0	1
Lanosterol 14-alpha demethylase	0	1	1	2
Aromatase	0	1	0	1
Cytochrome P450 11B1, mitochondrial	0	1	0	1
Cytochrome P450 11B2, mitochondrial	0	1	0	1
Heme oxygenase 2	0	1	0	1
Malate dehydrogenase, cytoplasmic	0	1	0	1
Cytochrome P450 144	0	0	1	1
Steroid C26-monooxygenase	0	0	1	1
Steroid C26-monooxygenase	0	0	1	1
Mycocyclosin synthase	0	0	1	1
Lanosterol 14-alpha demethylase	0	0	1	1
Lanosterol 14-alpha demethylase	0	0	1	1
Sterol 14-alpha demethylase	0	0	1	1
Sterol 14-alpha demethylase	0	1	1	2
14-alpha sterol demethylase	0	0	1	1
heat shock protein 90, putative	0	0	0	2
Glucose-6-phosphate 1-dehydrogenase	0	1	0	1
Serum paraoxonase/arylesterase 1	0	1	0	1
Corticosteroid 11-beta-dehydrogenase isozyme 1	0	1	0	1
Adenosine receptor A1	0	1	0	1
Corticosteroid 11-beta-dehydrogenase isozyme 1	0	1	0	1
6-phosphogluconate dehydrogenase, decarboxylating	0	1	0	1
Holo-[acyl-carrier-protein] synthase	0	1	0	1
Solute carrier organic anion transporter family member 2A1	0	1	0	1
Sodium/bile acid cotransporter	0	2	0	2
CDGSH iron-sulfur domain-containing protein 1	0	2	0	2
Broad substrate specificity ATP-binding cassette transporter ABCG2	0	4	0	4
Pancreatic triacylglycerol lipase	0	1	0	1
Tissue-type plasminogen activator	0	1	0	1
Plasminogen activator inhibitor 1	0	1	0	1
Urokinase-type plasminogen activator	0	1	0	1
72 kDa type IV collagenase	0	1	0	1
Matrilysin	0	1	0	1
L-selectin	0	1	0	1
P-selectin	0	1	0	1
E-selectin	0	1	0	1
Dipeptidyl peptidase 4	0	2	0	2
Alpha-synuclein	1	3	0	4
4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase FUT6	0	1	0	1
Anthrax toxin receptor 2	0	1	0	1
Alpha-(1,3)-fucosyltransferase 7	0	1	0	1
CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1	0	1	0	1
Reverse transcriptase/RNaseH	0	2	2	7
Toll-like receptor 2	0	1	0	1
Chain A, GLUTAMATE RECEPTOR SUBUNIT 2	0	1	0	1
Chain A, Glutamate Receptor Subunit 2	0	1	0	1
Chain B, Glutamate Receptor Subunit 2	0	1	0	1
Chain A, Slr1257 protein	0	0	1	1
Chain A, Glucosamine--fructose-6-phosphate aminotransferase [isomerizing]	0	1	0	1
beta-2 adrenergic receptor	2	0	0	2
Metabotropic glutamate receptor 8	0	2	0	2
Metabotropic glutamate receptor 6	0	1	1	3
Glutamate receptor ionotropic, NMDA 2D	0	2	0	2
Excitatory amino acid transporter 4	0	1	0	1
Glutamate receptor ionotropic, NMDA 3B	0	2	0	2
Bifunctional aspartokinase/homoserine dehydrogenase 1	0	1	0	1
Glutamate receptor ionotropic, kainate 1	0	2	1	3
Metabotropic glutamate receptor 1	0	1	1	2
Metabotropic glutamate receptor 2	0	0	1	1
Metabotropic glutamate receptor 3	0	0	1	1
Metabotropic glutamate receptor 4	0	1	1	2
Metabotropic glutamate receptor 5	0	0	1	1
Metabotropic glutamate receptor 6	0	0	1	1
Metabotropic glutamate receptor 7	0	0	1	1
Glutamate receptor ionotropic, kainate 1	0	1	1	2
Metabotropic glutamate receptor 5	0	1	1	3
Glutamate receptor ionotropic, kainate 2	0	2	1	3
Glutamate receptor 1	0	2	1	3
Glutamate receptor 2	0	2	1	3
Glutamate receptor 3	0	1	1	2
Glutamate receptor ionotropic, kainate 3	0	2	0	2
Excitatory amino acid transporter 1	0	2	0	3
Excitatory amino acid transporter 2	0	2	0	3
Excitatory amino acid transporter 3	0	2	0	3
Metabotropic glutamate receptor 8	0	0	1	1
Glutamate receptor 4	0	2	1	3
Excitatory amino acid transporter 3	0	0	0	1
Glutamate racemase	0	0	0	1
Metabotropic glutamate receptor 8	0	1	1	2
Fatty-acid amide hydrolase 1	0	2	0	2
Glutamate receptor ionotropic, NMDA 2A	0	6	2	12
Glutamate receptor ionotropic, NMDA 2B	0	6	2	12
Glutamate receptor ionotropic, NMDA 2C	0	6	2	12
Glutamate receptor ionotropic, kainate 4	0	2	0	2
Glutamate carboxypeptidase 2	0	1	0	1
Glutamate receptor ionotropic, NMDA 1	0	3	0	3
Glutamate receptor ionotropic, NMDA 2A	0	3	0	3
Glutamate receptor ionotropic, kainate 2	0	1	1	2
Glutamate receptor ionotropic, kainate 3	0	1	0	1
Glutamate receptor ionotropic, NMDA 2B	0	3	0	3
Metabotropic glutamate receptor 1	0	1	1	3
Metabotropic glutamate receptor 2	0	1	1	3
Metabotropic glutamate receptor 7	0	1	1	3
Metabotropic glutamate receptor 3	0	1	1	3
Metabotropic glutamate receptor 4	0	1	1	3
Glutamate receptor ionotropic, NMDA 2C	0	2	0	2
Glutamate receptor ionotropic, kainate 5	0	1	0	1
Glutamate receptor ionotropic, NMDA 2D	0	6	2	12
Glutamate receptor ionotropic, kainate 5	0	2	0	2
Glutamate racemase	0	0	0	1
Glutamate receptor ionotropic, NMDA 3A	0	2	0	2
Glutamate receptor ionotropic, NMDA 3B	0	6	2	12
Glutamate receptor ionotropic, NMDA 3A	0	6	2	12
Chain A, Glutamine Binding Protein	0	0	1	1
Asc-type amino acid transporter 1	0	1	0	1
Glycine receptor subunit alpha-1	0	0	1	1
Sodium- and chloride-dependent GABA transporter 2	0	1	0	1
Sodium- and chloride-dependent GABA transporter 3	0	1	0	1
Sodium- and chloride-dependent glycine transporter 1	0	1	0	1
Large neutral amino acids transporter small subunit 1	0	8	0	9
Serine racemase	0	1	0	1
Sodium- and chloride-dependent glycine transporter 2	0	1	0	1
Hypoxanthine-guanine phosphoribosyltransferase	0	0	0	1
Ricin	0	1	0	1
2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase	0	0	1	1
Purine nucleoside phosphorylase	0	0	1	2
Shiga toxin subunit A	0	1	0	1
Guanine deaminase	0	1	0	2
Chain A, TYROSINE PHOSPHATASE	0	1	0	1
Chain A, Tyrosine Phosphatase	0	1	0	1
Chain A, HISTIDINE-BINDING PROTEIN	0	0	1	1
Histidine-binding periplasmic protein	0	0	1	1
Glutamine synthetase	0	1	0	1
Gamma-aminobutyric acid receptor subunit pi	0	2	0	2
Gamma-aminobutyric acid receptor subunit delta	0	2	0	2
Stromelysin-1	0	1	2	3
Gamma-aminobutyric acid receptor subunit alpha-1	0	2	0	2
Urease subunit alpha	0	2	0	2
Gamma-aminobutyric acid receptor subunit beta-1	0	2	0	2
Gamma-aminobutyric acid receptor subunit gamma-2	0	2	0	2
Ribonucleoside-diphosphate reductase large subunit	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-3	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-5	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-3	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-2	0	2	0	2
Gamma-aminobutyric acid receptor subunit beta-2	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-4	0	2	0	2
Urease subunit beta	0	2	0	2
Gamma-aminobutyric acid receptor subunit epsilon	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-6	0	2	0	2
Gamma-aminobutyric acid receptor subunit gamma-1	0	2	0	2
Gamma-aminobutyric acid receptor subunit gamma-3	0	2	0	2
Gamma-aminobutyric acid receptor subunit theta	0	2	0	2
Geranylgeranyl pyrophosphate synthase	0	1	0	1
Farnesyl pyrophosphate synthase	0	2	0	2
Acid-sensing ion channel 3	0	1	0	1
Solute carrier organic anion transporter family member 1A4	0	4	0	6
Dihydrofolate reductase	0	5	0	5
Albumin	0	1	0	1
Albumin	0	0	2	2
Fatty acid-binding protein, intestinal	0	1	0	1
Polyunsaturated fatty acid 5-lipoxygenase	0	1	0	2
Caspase-1	0	2	0	2
UDP-glucuronosyltransferase 1A3	0	0	0	1
Aldo-keto reductase family 1 member C3	0	1	0	1
Caspase-3	0	1	0	1
Solute carrier organic anion transporter family member 1A1	0	3	0	3
Caspase-4	0	1	0	1
Caspase-5	0	1	0	1
Caspase-9	0	1	0	1
Acid-sensing ion channel 1	0	1	0	1
Dehydrogenase/reductase SDR family member 9	0	1	0	1
Chain A, PROTEIN (PROTEASE)	0	1	0	1
Chain B, PROTEIN (PROTEASE)	0	1	0	1
Chain A, PROTEIN (PROTEASE)	0	1	0	1
Chain B, PROTEIN (PROTEASE)	0	1	0	1
Chain A, HIV-1 PROTEASE	0	1	0	1
Chain B, HIV-1 PROTEASE	0	1	0	1
Chain A, HIV-II PROTEASE	0	1	0	1
Chain B, HIV-II PROTEASE	0	1	0	1
Chain A, POL polyprotein	0	0	1	1
Chain B, POL polyprotein	0	0	1	1
Chain A, POL polyprotein	0	0	1	1
Chain B, POL polyprotein	0	0	1	1
Chain A, POL polyprotein	0	0	1	1
Chain B, POL polyprotein	0	0	1	1
Chain A, POL polyprotein	0	0	1	1
Chain B, POL polyprotein	0	0	1	1
Chain A, protease RETROPEPSIN	0	1	0	1
Chain B, protease RETROPEPSIN	0	1	0	1
Chain A, protease RETROPEPSIN	0	1	0	1
Chain B, protease RETROPEPSIN	0	1	0	1
Chain A, protease RETROPEPSIN	0	1	0	1
Chain B, protease RETROPEPSIN	0	1	0	1
Chain A, POL polyprotein	0	2	0	2
Chain B, POL polyprotein	0	2	0	2
Chain A, POL polyprotein	0	2	0	2
Chain B, POL polyprotein	0	2	0	2
Chain A, HIV-1 protease	0	1	0	1
Chain B, HIV-1 protease	0	1	0	1
Chain A, Pol polyprotein	0	1	0	1
Chain B, Pol polyprotein	0	1	0	1
Chain A, Pol polyprotein	0	1	0	1
Chain B, Pol polyprotein	0	1	0	1
Chain A, Pol polyprotein	0	1	0	1
Chain B, Pol polyprotein	0	1	0	1
Chain A, Pol polyprotein	0	1	0	1
Chain B, Pol polyprotein	0	1	0	1
Chain A, Hiv-1 Protease	0	1	0	1
Chain B, Hiv-1 Protease	0	1	0	1
Chain A, Hiv-1 Protease	0	1	0	1
Chain B, Hiv-1 Protease	0	1	0	1
Chain A, Hiv-1 Protease	0	1	0	1
Chain B, Hiv-1 Protease	0	1	0	1
Gag-Pol polyprotein	0	3	0	3
Gag-Pol polyprotein	0	1	0	1
Gag-Pol polyprotein	0	2	0	2
Gag polyprotein	0	1	0	1
Gag-Pol polyprotein	0	2	0	2
Gag-Pol polyprotein	0	3	0	3
Alpha-1D adrenergic receptor	0	3	0	3
Thromboxane-A synthase	0	2	0	2
Gag-Pol polyprotein	0	2	0	2
Thromboxane-A synthase	0	0	0	2
Genome polyprotein	0	1	0	1
Protease	0	5	3	12
Multidrug and toxin extrusion protein 2	0	2	0	2
Protease	0	4	2	6
Protease	0	1	0	1
Neuronal acetylcholine receptor subunit beta-2	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-7	0	1	0	1
Acetylcholinesterase	0	0	1	1
Fatty acid synthase	0	1	0	1
Liver carboxylesterase	0	1	0	1
Sodium channel protein type 4 subunit alpha	0	1	0	1
Chain A, AMINOPEPTIDASE	0	2	0	2
Chain A, AMINOPEPTIDASE	0	2	0	2
Chain A, Leucine Aminopeptidase	0	1	0	1
Alkaline phosphatase, tissue-nonspecific isozyme	0	3	0	3
Intestinal-type alkaline phosphatase	0	3	0	3
Phospholipase A-2-activating protein	0	3	0	3
Gonadotropin-releasing hormone receptor	0	1	0	1
Gonadotropin-releasing hormone receptor	0	2	0	2
Type-1A angiotensin II receptor	0	1	0	1
Type-1B angiotensin II receptor	0	2	0	2
Type-2 angiotensin II receptor	0	1	0	1
cGMP-inhibited 3',5'-cyclic phosphodiesterase B	0	1	0	1
cGMP-inhibited 3',5'-cyclic phosphodiesterase A	0	1	0	1
5-hydroxytryptamine receptor 1A	0	1	0	1
Type-1 angiotensin II receptor	0	1	0	1
Chain A, Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplast	0	1	0	1
Chain A, Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplast	0	1	0	1
LacZ protein (plasmid)	0	1	0	1
[tau protein] kinase	0	1	0	1
C-C chemokine receptor type 6	0	1	0	1
Vpr	2	0	0	2
Glycogen synthase kinase-3 alpha	0	1	1	2
Large neutral amino acids transporter small subunit 1	0	2	0	2
Sodium-dependent dopamine transporter	0	1	0	1
Kappa-type opioid receptor	0	1	0	1
Mu-type opioid receptor	0	1	0	1
cystic fibrosis transmembrane conductance regulator ATP-binding cassette sub-family C member 7	0	0	0	1
Cannabinoid receptor 1	0	2	0	2
Voltage-dependent L-type calcium channel subunit alpha-1F	0	3	0	3
D(2) dopamine receptor	0	1	0	1
Cytochrome P450 2B6	0	2	1	4
D(4) dopamine receptor	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1D	0	3	0	3
Voltage-dependent L-type calcium channel subunit alpha-1S	0	3	0	3
Voltage-dependent L-type calcium channel subunit alpha-1C	0	3	0	3
Mas-related G-protein coupled receptor member X2	0	0	1	1
Aldehyde oxidase 1	0	1	0	1
Thioredoxin reductase	0	1	0	1
Flavodoxin	0	0	0	1
Chain A, Inosine-5'-Monophosphate Dehydrogenase 2	0	1	0	1
Inosine-5'-monophosphate dehydrogenase 2	0	2	1	3
Inosine-5'-monophosphate dehydrogenase 1	0	2	0	2
Peroxisome proliferator-activated receptor gamma	0	0	5	5
Inosine-5'-monophosphate dehydrogenase	0	1	0	2
UDP-glucuronosyltransferase 1A7	0	0	0	1
UDP-glucuronosyltransferase 1A10	0	0	0	1
UDP-glucuronosyltransferase 1A8	0	0	0	1
Chain A, Venom Allergen 2	0	0	1	1
Sodium channel protein type 1 subunit alpha	0	1	0	1
Sodium channel protein type 2 subunit alpha	0	1	0	1
Sodium channel protein type 3 subunit alpha	0	1	0	1
Oxytocin receptor	0	0	1	1
tyrosine-protein kinase Yes	2	0	0	2
Bone morphogenetic protein receptor type-1B	0	0	1	1
Cell division cycle 7-related protein kinase	0	0	1	1
ATP-dependent RNA helicase DDX3X	0	0	1	1
Pyridoxal kinase	0	0	1	1
Citron Rho-interacting kinase	0	0	1	1
Serine/threonine-protein kinase Chk1	0	0	1	1
Cyclin-G-associated kinase	0	0	1	1
Ephrin type-B receptor 6	0	0	1	1
Peroxisomal acyl-coenzyme A oxidase 3	0	0	1	1
Receptor-interacting serine/threonine-protein kinase 2	0	0	1	1
Mitotic checkpoint serine/threonine-protein kinase BUB1	0	0	1	1
Testosterone 17-beta-dehydrogenase 3	0	1	0	1
Dynamin-like 120 kDa protein, mitochondrial	0	0	1	1
Putative nucleoside diphosphate kinase	0	0	1	1
Tyrosine-protein kinase JAK2	0	2	0	2
Rho-associated protein kinase 2	0	0	1	1
Serine/threonine-protein kinase ULK1	0	0	1	1
Serine/threonine-protein kinase/endoribonuclease IRE1	0	0	1	1
Ribosomal protein S6 kinase alpha-5	0	0	1	1
U5 small nuclear ribonucleoprotein 200 kDa helicase	0	0	1	1
Ribosomal protein S6 kinase alpha-4	0	0	1	1
Serine/threonine-protein kinase 16	0	0	1	1
Serine/threonine-protein kinase 10	0	0	1	1
Serine/threonine-protein kinase D3	0	0	1	1
Structural maintenance of chromosomes protein 2	0	0	1	1
Mitogen-activated protein kinase kinase kinase 6	0	0	1	1
Mitogen-activated protein kinase kinase kinase kinase 4	0	0	1	1
Serine/threonine-protein kinase LATS1	0	0	1	1
Serine/threonine-protein kinase PAK 4	0	0	1	1
Tyrosine-protein kinase ABL1	0	0	1	1
High affinity nerve growth factor receptor	0	0	1	1
Guanine nucleotide-binding protein G(i) subunit alpha-2	0	0	1	1
ADP/ATP translocase 2	0	0	1	1
Protein kinase C beta type	0	1	1	2
Tyrosine-protein kinase Lck	0	1	1	2
Glycogen phosphorylase, liver form	0	0	1	1
Tyrosine-protein kinase Fes/Fps	0	0	1	1
Macrophage colony-stimulating factor 1 receptor	0	1	0	1
Adenine phosphoribosyltransferase	0	0	1	1
Tyrosine-protein kinase Yes	0	1	1	2
Tyrosine-protein kinase Lyn	0	1	1	2
Signal recognition particle receptor subunit alpha	0	0	1	1
Cytochrome c1, heme protein, mitochondrial	0	0	1	1
Tyrosine-protein kinase HCK	0	1	1	2
Tyrosine-protein kinase Fgr	0	1	0	1
Serine/threonine-protein kinase A-Raf	0	0	1	1
Cytochrome P450 2C8	0	1	0	2
Glycogen phosphorylase, brain form	0	0	1	1
Breakpoint cluster region protein	0	0	1	1
Fibroblast growth factor receptor 1	0	0	1	1
DNA topoisomerase 2-alpha	0	0	1	1
ADP/ATP translocase 3	0	0	1	1
cAMP-dependent protein kinase type II-alpha regulatory subunit	0	0	1	1
Phosphorylase b kinase gamma catalytic chain, liver/testis isoform	0	0	1	1
Tyrosine-protein kinase Fer	0	0	1	1
Protein kinase C alpha type	0	0	1	1
General transcription and DNA repair factor IIH helicase subunit XPD	0	0	1	1
Ras-related protein Rab-6A	0	0	1	1
Ephrin type-A receptor 1	0	0	1	1
Receptor tyrosine-protein kinase erbB-3	0	1	0	1
Multifunctional protein ADE2	0	0	1	1
Nucleoside diphosphate kinase B	0	0	1	1
Ferrochelatase, mitochondrial	0	0	1	1
Ribosomal protein S6 kinase beta-1	0	0	1	1
Tyrosine-protein kinase JAK1	0	2	1	3
G1/S-specific cyclin-E1	0	1	0	1
Beta-adrenergic receptor kinase 1	0	0	1	1
Probable ATP-dependent RNA helicase DDX6	0	0	1	1
Mitogen-activated protein kinase 3	0	0	1	1
MAP/microtubule affinity-regulating kinase 3	0	0	1	1
Deoxycytidine kinase	0	0	1	1
Ephrin type-A receptor 2	0	1	1	2
Ephrin type-B receptor 2	0	0	1	1
Non-receptor tyrosine-protein kinase TYK2	0	0	1	1
Phosphatidylethanolamine-binding protein 1	0	0	1	1
Wee1-like protein kinase	0	0	1	1
Heme oxygenase 2	0	0	1	1
S-adenosylmethionine synthase isoform type-2	0	0	1	1
DnaJ homolog subfamily A member 1	0	0	1	1
RAC-beta serine/threonine-protein kinase	0	0	1	1
Dual specificity protein kinase TTK	0	0	1	1
DNA replication licensing factor MCM4	0	0	1	1
Myosin-10	0	0	1	1
Dual specificity mitogen-activated protein kinase kinase 2	0	1	1	2
Bone morphogenetic protein receptor type-1A	0	0	1	1
Activin receptor type-1B	0	0	1	1
TGF-beta receptor type-1	0	0	1	1
TGF-beta receptor type-2	0	0	1	1
Tyrosine-protein kinase CSK	0	1	1	2
Glycine--tRNA ligase	0	0	1	1
Protein kinase C iota type	0	0	1	1
Exosome RNA helicase MTR4	0	0	1	1
Tyrosine-protein kinase Tec	0	1	1	2
Tyrosine-protein kinase TXK	0	1	1	2
Tyrosine-protein kinase ABL2	0	0	1	1
Tyrosine-protein kinase FRK	0	1	1	2
G protein-coupled receptor kinase 6	0	0	1	1
Tyrosine-protein kinase SYK	0	1	1	2
Mitogen-activated protein kinase 8	0	0	1	1
Mitogen-activated protein kinase 9	0	0	1	1
Dual specificity mitogen-activated protein kinase kinase 3	0	0	1	1
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha	0	0	1	1
Casein kinase I isoform delta	0	0	1	1
MAP kinase-activated protein kinase 2	0	0	1	1
Elongation factor Tu, mitochondrial	0	0	1	1
Choline-phosphate cytidylyltransferase A	0	0	1	1
Casein kinase I isoform epsilon	0	0	1	1
Very long-chain specific acyl-CoA dehydrogenase, mitochondrial	0	0	1	1
Dual specificity protein kinase CLK1	0	0	1	1
Dual specificity protein kinase CLK2	0	0	1	1
Cyclin-dependent kinase 7	0	0	1	1
Cyclin-dependent kinase 9	0	0	1	1
Ras-related protein Rab-27A	0	0	1	1
Tyrosine-protein kinase Blk	0	1	1	2
Interleukin-1 receptor-associated kinase 1	0	0	1	1
Ribosomal protein S6 kinase alpha-3	0	0	1	1
Cytoplasmic tyrosine-protein kinase BMX	0	2	1	3
cAMP-dependent protein kinase catalytic subunit PRKX	0	0	1	1
Serine/threonine-protein kinase Nek2	0	0	1	1
Serine/threonine-protein kinase Nek3	0	0	1	1
Tyrosine-protein kinase JAK3	0	1	1	2
Dual specificity mitogen-activated protein kinase kinase 6	0	0	1	1
LIM domain kinase 1	0	0	1	1
LIM domain kinase 2	0	0	1	1
Mitogen-activated protein kinase 10	0	0	1	1
Tyrosine--tRNA ligase, cytoplasmic	0	0	1	1
5'-AMP-activated protein kinase subunit gamma-1	0	0	1	2
Ephrin type-B receptor 3	0	0	1	1
Ephrin type-A receptor 5	0	0	1	1
Ephrin type-A receptor 4	0	0	1	1
Adenylate kinase 2, mitochondrial	0	0	1	1
Adenosine kinase	0	0	1	1
Ras-related protein Rab-10	0	0	1	1
Actin-related protein 3	0	0	1	1
Actin-related protein 2	0	0	1	1
GTP-binding nuclear protein Ran	0	0	1	1
Casein kinase I isoform gamma-2	0	0	1	1
Cyclin-dependent kinase 3	0	0	1	1
Cyclin-dependent kinase 6	0	0	1	1
Cyclin-dependent-like kinase 5	0	0	1	1
Cyclin-dependent kinase 16	0	0	1	1
Cyclin-dependent kinase 17	0	0	1	1
ATP-dependent 6-phosphofructokinase, platelet type	0	0	1	1
Dual specificity mitogen-activated protein kinase kinase 1	0	0	1	1
DNA topoisomerase 2-beta	0	0	1	1
Protein kinase C theta type	0	0	1	1
Activin receptor type-1	0	0	1	1
Macrophage-stimulating protein receptor	0	0	1	1
Protein kinase C delta type	0	0	1	1
Tyrosine-protein kinase BTK	0	2	2	4
Activated CDC42 kinase 1	0	0	1	1
Epithelial discoidin domain-containing receptor 1	0	0	1	1
Tyrosine-protein kinase ITK/TSK	0	1	1	2
Mitogen-activated protein kinase kinase kinase kinase 2	0	0	1	1
Tyrosine-protein kinase Mer	0	0	1	1
Serine/threonine-protein kinase 4	0	0	1	1
5'-AMP-activated protein kinase catalytic subunit alpha-1	0	0	1	2
Dual specificity mitogen-activated protein kinase kinase 5	0	0	1	1
Mitogen-activated protein kinase 7	0	0	1	1
Serine/threonine-protein kinase PAK 2	0	0	1	1
Serine/threonine-protein kinase 3	0	0	1	1
Mitogen-activated protein kinase kinase kinase 1	0	0	1	1
Integrin-linked protein kinase	0	0	1	1
Rho-associated protein kinase 1	0	0	1	1
Non-receptor tyrosine-protein kinase TNK1	0	0	1	1
Calcium/calmodulin-dependent protein kinase type II subunit gamma	0	0	1	1
Calcium/calmodulin-dependent protein kinase type II subunit delta	0	0	1	1
Activin receptor type-2B	0	0	1	1
Bone morphogenetic protein receptor type-2	0	0	1	1
Protein-tyrosine kinase 6	0	1	1	2
cGMP-dependent protein kinase 1	0	0	1	1
Cyclin-dependent kinase 13	0	0	1	1
Inhibitor of nuclear factor kappa-B kinase subunit epsilon	0	0	1	1
Protein-tyrosine kinase 2-beta	0	0	1	1
Maternal embryonic leucine zipper kinase	0	0	1	1
Structural maintenance of chromosomes protein 1A	0	0	1	1
Chromodomain-helicase-DNA-binding protein 4	0	0	1	1
Serine/threonine-protein kinase 38	0	0	1	1
Receptor tyrosine-protein kinase erbB-4	0	1	1	2
Ephrin type-A receptor 7	0	0	1	1
Delta(24)-sterol reductase	0	0	1	1
Ribosomal protein S6 kinase alpha-1	0	1	1	2
Myosin light chain kinase, smooth muscle	0	0	1	1
Mitogen-activated protein kinase 11	0	0	1	1
Serine/threonine-protein kinase STK11	0	0	1	1
Serine/threonine-protein kinase N1	0	0	1	1
Serine/threonine-protein kinase N2	0	0	1	1
Calcium/calmodulin-dependent protein kinase type IV	0	0	1	1
Mitogen-activated protein kinase kinase kinase 11	0	0	1	1
MAP kinase-activated protein kinase 3	0	0	1	1
Discoidin domain-containing receptor 2	0	0	1	1
AP2-associated protein kinase 1	0	0	1	1
Myosin light chain kinase 3	0	0	1	1
Putative heat shock protein HSP 90-beta 2	0	0	1	1
Rab-like protein 3	0	0	1	1
Serine/threonine-protein kinase MRCK alpha	0	0	1	1
Serine/threonine-protein kinase MRCK gamma	0	0	1	1
Acyl-CoA dehydrogenase family member 10	0	0	1	1
Serine/threonine-protein kinase ULK3	0	0	1	1
Uncharacterized protein FLJ45252	0	0	1	1
Acyl-CoA dehydrogenase family member 11	0	0	1	1
Serine/threonine-protein kinase/endoribonuclease IRE2	0	0	1	1
Serine/threonine-protein kinase MARK2	0	0	1	1
ATP-dependent RNA helicase DHX30	0	0	1	1
Serine/threonine-protein kinase TAO1	0	0	1	1
STE20-related kinase adapter protein alpha	0	0	1	1
Myosin-14	0	0	1	1
AarF domain-containing protein kinase 1	0	0	1	1
ATP-dependent RNA helicase DDX42	0	0	1	1
Mitogen-activated protein kinase kinase kinase kinase 3	0	0	1	1
MAP kinase-activated protein kinase 5	0	0	1	1
Misshapen-like kinase 1	0	0	1	1
Atypical kinase COQ8A, mitochondrial	0	0	1	1
Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma	0	0	1	1
Mitogen-activated protein kinase 15	0	0	1	1
Serine/threonine-protein kinase Nek9	0	0	1	1
Serine/threonine-protein kinase Nek7	0	0	1	1
ATP-dependent RNA helicase DDX1	0	0	1	1
Nuclear receptor subfamily 4 group A member 3	0	1	0	1
Mitogen-activated protein kinase kinase kinase kinase 1	0	0	1	1
MAP/microtubule affinity-regulating kinase 4	0	0	1	1
Calcium/calmodulin-dependent protein kinase type 1G	0	0	1	1
Serine/threonine-protein kinase Nek1	0	0	1	1
PAS domain-containing serine/threonine-protein kinase	0	0	1	1
Calcium/calmodulin-dependent protein kinase kinase 2	0	0	1	1
EKC/KEOPS complex subunit TP53RK	0	0	1	1
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase	0	0	1	1
Mitogen-activated protein kinase kinase kinase 5	0	0	1	1
Mitogen-activated protein kinase kinase kinase 3	0	0	1	1
Eukaryotic translation initiation factor 2-alpha kinase 1	0	0	1	1
Peroxiredoxin-like 2A	0	1	0	1
Nucleolar GTP-binding protein 1	0	0	1	1
Serine/threonine-protein kinase D2	0	0	1	1
NUAK family SNF1-like kinase 2	0	0	1	1
RNA cytidine acetyltransferase	0	0	1	1
Serine/threonine-protein kinase SIK2	0	0	1	1
STE20-like serine/threonine-protein kinase	0	0	1	1
Serine/threonine-protein kinase TAO3	0	0	1	1
dCTP pyrophosphatase 1	0	0	1	1
Dual specificity protein kinase CLK4	0	0	1	1
Platelet glycoprotein VI	0	1	0	1
Casein kinase I isoform gamma-1	0	0	1	1
Serine/threonine-protein kinase PAK 6	0	0	1	1
Phenylalanine--tRNA ligase beta subunit	0	0	1	1
BMP-2-inducible protein kinase	0	0	1	1
Obg-like ATPase 1	0	0	1	1
Midasin	0	0	1	1
Interleukin-1 receptor-associated kinase 4	0	0	1	1
Mitogen-activated protein kinase kinase kinase 20	0	0	1	1
Cyclin-dependent kinase 12	0	0	1	1
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13	0	0	1	1
Serine/threonine-protein kinase 26	0	0	1	1
Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial	0	0	1	1
Serine/threonine-protein kinase NLK	0	0	1	1
5'-AMP-activated protein kinase subunit gamma-2	0	0	1	2
Serine/threonine-protein kinase TBK1	0	0	1	1
Septin-9	0	0	1	1
Ribosomal protein S6 kinase alpha-6	0	0	1	1
TRAF2 and NCK-interacting protein kinase	0	0	1	1
Serine/threonine-protein kinase TAO2	0	0	1	1
Serine/threonine-protein kinase ICK	0	0	1	1
RAC-gamma serine/threonine-protein kinase	0	0	1	1
Serine/threonine-protein kinase SIK3	0	0	1	1
Mitogen-activated protein kinase kinase kinase 2	0	0	1	1
Thyroid hormone receptor-associated protein 3	0	0	1	1
Dual specificity tyrosine-phosphorylation-regulated kinase 1B	0	0	1	1
Mitogen-activated protein kinase kinase kinase kinase 5	0	0	1	1
Receptor-interacting serine/threonine-protein kinase 3	0	0	1	1
Serine/threonine-protein kinase MRCK beta	0	0	1	1
Interleukin-1 receptor-associated kinase 3	0	0	1	1
Serine/threonine-protein kinase 24	0	0	1	1
Casein kinase I isoform gamma-3	0	0	1	1
Mitogen-activated protein kinase kinase kinase 4	0	0	1	1
Cytochrome P450 1A2	0	0	0	2
Arylacetamide deacetylase	0	1	0	3
Arylacetamide deacetylase	0	0	0	1
Arylacetamide deacetylase	0	0	0	1
electroneutral potassium-chloride cotransporter KCC2	0	0	1	1
G-protein coupled receptor 55	0	1	0	1
Thymidylate synthase	0	1	0	1
Thymidylate synthase	0	1	0	1
Thymidylate synthase	0	1	0	1
Thymidylate synthase	0	1	0	1
Voltage-dependent calcium channel subunit alpha-2/delta-1	0	1	0	1
Alkaline phosphatase, tissue-nonspecific isozyme	0	1	0	1
Intestinal-type alkaline phosphatase	0	1	0	1
E3 ubiquitin-protein ligase XIAP	0	1	0	1
SLC16A10 protein	0	0	0	3
Monocarboxylate transporter 10	0	0	0	3
Estrogen receptor 1	0	1	0	1
fMet-Leu-Phe receptor	0	1	0	1
mu-type opioid receptor isoform MOR-1	0	0	1	1
5-hydroxytryptamine receptor 2A	0	0	1	1
luciferase	0	0	0	1
Progesterone receptor	0	2	0	3
Glucocorticoid receptor	0	1	1	2
Glucocorticoid receptor	0	0	1	1
Mineralocorticoid receptor	0	2	1	3
Glutamine synthetase	0	0	1	1
Nociceptin receptor	0	0	1	1
Estrogen receptor beta	0	2	0	2
tyrosine-protein phosphatase non-receptor type 22 isoform 1	0	1	0	1
cGMP-dependent 3',5'-cyclic phosphodiesterase	0	1	0	1
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Estrogen receptor	0	0	1	1
Beta-hexosaminidase subunit alpha	0	1	0	2
Beta-hexosaminidase subunit beta	0	1	0	1
Dihydrofolate reductase	0	2	1	4
Bifunctional dihydrofolate reductase-thymidylate synthase	0	2	0	2
Dihydrofolate reductase	0	2	0	2
Substance-K receptor	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Pteridine reductase 1	0	1	0	1
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Trace amine-associated receptor 5	0	0	1	1
Estrogen receptor beta	0	0	1	1
Bifunctional dihydrofolate reductase-thymidylate synthase	0	2	0	2
Multidrug and toxin extrusion protein 1	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Sucrase-isomaltase, intestinal	0	1	0	1
5-lipoxygenase	0	1	0	1
NS5	0	0	2	2
glycogen synthase kinase-3 beta isoform 1	0	0	1	1
Polymerase basic protein 2	0	0	1	1
RNA-directed RNA polymerase catalytic subunit	0	0	1	1
Polymerase acidic protein	0	0	2	2
Adenosylhomocysteinase	0	0	0	2
Adenosine receptor A2a	0	1	0	1
Adenosine receptor A1	0	3	0	3
Adenosine receptor A1	0	1	0	1
Genome polyprotein	0	0	1	1
DNA-directed RNA polymerase subunit beta	0	1	0	1
Nuclear receptor subfamily 1 group I member 2	0	0	4	4
Solute carrier organic anion transporter family member 2B1	0	5	0	5
NH(3)-dependent NAD(+) synthetase	0	1	0	1
Solute carrier organic anion transporter family member 1A2	0	2	0	4
Glutathione S-transferase omega-1	0	1	0	1
DNA gyrase subunit B	0	1	0	1
DNA gyrase subunit A	0	1	0	1
Enoyl-[acyl-carrier-protein] reductase [NADH]	0	1	0	1
DNA-directed RNA polymerase subunit beta	0	1	0	1
DNA-directed RNA polymerase subunit beta	0	1	0	1
B-cell lymphoma 6 protein	0	0	1	1
DNA-directed RNA polymerase subunit beta	0	1	0	1
Chain A, HIV-1 PROTEASE	0	1	0	1
Chain B, HIV-1 PROTEASE	0	1	0	1
Chain A, Endothiapepsin	0	1	0	1
Chain A, Endothiapepsin	0	1	0	1
Gag-Pol polyprotein	0	1	0	1
Cytochrome P450 3A5	0	2	0	2
Plasmepsin V	0	1	0	1
inositol monophosphatase 1	1	0	0	1
Prostaglandin G/H synthase 2	0	1	0	1
Cytochrome c oxidase subunit 1	0	1	0	1
C-X-C chemokine receptor type 3	0	1	0	1
Transporter	0	1	0	1
Sodium-dependent serotonin transporter	0	1	0	1
chaperonin-containing TCP-1 beta subunit homolog	1	0	0	1
Estrogen receptor beta	0	0	0	1
Polyphenol oxidase 2	0	1	0	3
5'-AMP-activated protein kinase subunit beta-2	0	0	0	1
Tyrosine-protein phosphatase YopH	0	1	0	1
High mobility group protein B1	0	0	1	1
Tyrosine-protein phosphatase non-receptor type 1	0	1	0	3
Estrogen receptor	0	0	0	1
Cystathionine gamma-lyase	0	1	0	1
5'-AMP-activated protein kinase catalytic subunit alpha-2	0	0	0	1
Xanthine dehydrogenase/oxidase	0	1	0	1
Solute carrier family 22 member 7	0	0	0	2
Ubiquitin-like domain-containing CTD phosphatase 1	0	1	0	1
5'-AMP-activated protein kinase subunit gamma-3	0	0	0	1
5'-AMP-activated protein kinase subunit beta-1	0	0	0	1
Pyruvate kinase PKM	0	0	1	1
Peroxisome proliferator-activated receptor alpha	1	0	0	1
Cereblon isoform 4	0	1	0	1
Protein cereblon	0	2	0	2
Peptidyl-prolyl cis-trans isomerase FKBP1A	0	2	1	3
Peptidyl-prolyl cis-trans isomerase FKBP1B	0	0	1	1
Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform	0	1	0	1
Peptidyl-prolyl cis-trans isomerase FKBP5	0	1	0	1
Splicing factor 3B subunit 3	0	1	0	1
Chain X, Thyroid hormone receptor beta-1	0	0	2	2
Chain X, Thyroid hormone receptor beta-1	0	0	2	2
Solute carrier organic anion transporter family member 1A5	0	0	0	2
Transthyretin	0	1	0	3
Thyroid hormone receptor alpha	0	2	3	5
Thyroid hormone receptor beta	0	2	3	5
Proliferating cell nuclear antigen	0	2	0	2
Malate dehydrogenase, mitochondrial	0	1	0	1
Solute carrier organic anion transporter family member 1A3	0	0	0	3
Monocarboxylate transporter 8	0	0	0	1
Bile acid receptor	0	1	0	1
Solute carrier organic anion transporter family member 1C1	0	0	0	1
procathepsin L isoform 1 preproprotein	0	1	0	1
Thyroid hormone receptor beta	0	1	0	1
Sigma non-opioid intracellular receptor 1	0	0	1	1
Solute carrier organic anion transporter family member 4C1	0	0	0	1
Solute carrier organic anion transporter family member 4A1	0	0	0	1
Solute carrier organic anion transporter family member 1C1	0	1	0	1
Chain A, CARBONIC ANHYDRASE II	0	1	0	1
Chain A, Trp Rna-binding Attenuation Protein	0	0	1	1
Chain K, Trp Rna-binding Attenuation Protein	0	0	1	1
Chain B, tryptophanyl-tRNA synthetase	0	0	1	1
Chain C, Tryptophanyl-tRNA synthetase II	0	0	1	1
Indoleamine 2,3-dioxygenase 1	0	1	0	2
Tryptophan 2,3-dioxygenase	0	1	0	2
Uracil nucleotide/cysteinyl leukotriene receptor	0	1	0	1
Tryprostatin B synthase	0	0	0	1
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase	0	0	1	1
Chain A, CHORISMATE MUTASE	0	1	0	1
Chain A, TYROSYL-tRNA SYNTHETASE	0	0	1	1
Tubulin--tyrosine ligase	0	1	0	1
Taste receptor type 2 member 14	0	0	0	1
Chain A, Glycogen phosphorylase, liver form	0	0	1	1
Chain A, glycogen phosphorylase, liver form	0	0	1	1
Chain A, Glycogen phosphorylase, liver form	0	0	1	1
Chain A, Glycogen phosphorylase, liver form	0	0	1	1
Solute carrier family 2, facilitated glucose transporter member 9	0	1	1	2
Chain A, orotidine 5'-monophosphate decarboxylase	0	1	0	1
Chain B, orotidine 5'-monophosphate decarboxylase	0	1	0	1
Chain A, orotidine 5'-monophosphate decarboxylase	0	1	0	1
Chain A, orotidine monophosphate decarboxylase	0	1	0	1
Chain A, orotidine monophosphate decarboxylase	0	1	0	1
Chain B, orotidine monophosphate decarboxylase	0	1	0	1
Chain B, PyrR bifunctional protein	0	0	1	1
Orotidine 5'-phosphate decarboxylase	0	1	0	1
Uridine 5'-monophosphate synthase	0	1	0	1
UMP-CMP kinase	0	0	0	1
Orotidine 5'-phosphate decarboxylase	0	1	0	1
Protein argonaute-2	0	0	1	1
Chain A, Arginase 1	0	1	0	1
Alpha-2B adrenergic receptor	0	1	0	1
Alpha-2C adrenergic receptor	0	1	0	1
Alpha-2A adrenergic receptor	0	1	0	1
D-alanyl-D-alanine dipeptidase	0	1	0	1
Transporter	0	1	0	1
Vitamin K epoxide reductase complex subunit 1	0	0	0	1
Vitamin K epoxide reductase complex subunit 1-like protein 1	0	1	0	1
Vitamin K epoxide reductase complex subunit 1	0	1	0	1
Vitamin K epoxide reductase complex subunit 1-like protein 1	0	1	0	1
Vitamin K epoxide reductase complex subunit 1	0	2	0	2
pyruvate kinase PKM isoform a	1	0	0	1
Ectonucleoside triphosphate diphosphohydrolase 1	0	0	0	1
DNA polymerase beta	0	1	0	1
Thymidine kinase, cytosolic	0	0	0	1
Thymidylate kinase	0	1	0	1
Protein kinase C epsilon type	0	1	0	1
Thymidine kinase	0	1	0	2
Solute carrier family 22 member 11	0	0	0	1
Thymidine kinase	0	1	0	2
Solute carrier family 22 member 7	0	0	0	1
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Synonyms(1)

Research Excerpts

Overview

Treatment

Research

Studies (737)

Protein Targets (1,706)

Hemophilia B

Synonyms(1)

Research Excerpts

Overview

Treatment

Research

Studies (737)

Drugs Studied (250)

Protein Targets (1,706)