aminocaproic acid has been researched along with Hemophilia B in 14 studies
Aminocaproic Acid: An antifibrinolytic agent that acts by inhibiting plasminogen activators which have fibrinolytic properties.
6-aminohexanoic acid : An epsilon-amino acid comprising hexanoic acid carrying an amino substituent at position C-6. Used to control postoperative bleeding, and to treat overdose effects of the thrombolytic agents streptokinase and tissue plasminogen activator.
Hemophilia B: A deficiency of blood coagulation factor IX inherited as an X-linked disorder. (Also known as Christmas Disease, after the first patient studied in detail, not the holy day.) Historical and clinical features resemble those in classic hemophilia (HEMOPHILIA A), but patients present with fewer symptoms. Severity of bleeding is usually similar in members of a single family. Many patients are asymptomatic until the hemostatic system is stressed by surgery or trauma. Treatment is similar to that for hemophilia A. (From Cecil Textbook of Medicine, 19th ed, p1008)
| Excerpt | Relevance | Reference |
|---|---|---|
| "This study evaluated the safety and efficacy of combined treatment with epsilon-aminocaproic acid or tranexamic acid and monoclonal antibody purified factor IX (MAb factor IX) for prophylaxis against bleeding in eight hemophilia B patients undergoing nine dental extraction procedures." | 5.08 | Safety and efficacy of purified factor IX concentrate and antifibrinolytic agents for dental extractions in hemophilia B. ( Djulbegovic, B; Goldsmith, G; Hadley, T; Joseph, G; Kushner, GM; Marasa, M; Pesto, A, 1996) |
| "In people with haemophilia or other congenital bleeding disorders undergoing surgical interventions, haemostatic treatment is needed in order to correct the underlying coagulation abnormalities and minimise the bleeding risk." | 2.52 | Treatment for preventing bleeding in people with haemophilia or other congenital bleeding disorders undergoing surgery. ( Coppola, A; Di Minno, MN; Tufano, A; Windyga, J; Yeung, C, 2015) |
| "Haemophilia is a congenital, life-long disorder that may cause major disabilities." | 2.37 | Comprehensive management of haemophilia. ( Dietrich, SL; Kasper, CK, 1985) |
| " Symptoms like mild nausea and vertigo were seen as the side-effects of this medicine when high intravenous dosage was administered." | 1.32 | Role of epsilon amino caproic acid in the management of haemophilic patients with inhibitors. ( Ghosh, K; Jijina, F; Mohanty, D; Shetty, S, 2004) |
| "In attenuated forms of haemophilia B (factor IX level between 5 and 15%) haemorrhages may be only occasional and occur only late in life." | 1.26 | [Heavy haematuria as the presentation of attenuated haemophilia B (author's transl)]. ( Bollack, C; Dufour, A; Guyen Qui, JL; Kalogjera, V; Masson, JC; Mayer, G; Oliveux, A, 1980) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (50.00) | 18.7374 |
| 1990's | 2 (14.29) | 18.2507 |
| 2000's | 2 (14.29) | 29.6817 |
| 2010's | 3 (21.43) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Coppola, A | 1 |
| Windyga, J | 1 |
| Tufano, A | 1 |
| Yeung, C | 1 |
| Di Minno, MN | 1 |
| van Galen, KP | 1 |
| Engelen, ET | 1 |
| Mauser-Bunschoten, EP | 1 |
| van Es, RJ | 1 |
| Schutgens, RE | 1 |
| Fogarty, PF | 1 |
| Kouides, P | 1 |
| STRAUSS, HS | 1 |
| KEVY, SV | 1 |
| DIAMOND, LK | 1 |
| TSEVRENIS, H | 1 |
| MANDALAKI, T | 1 |
| Ghosh, K | 1 |
| Shetty, S | 1 |
| Jijina, F | 1 |
| Mohanty, D | 1 |
| Wilker, SC | 1 |
| Singh, A | 1 |
| Ellis, FJ | 1 |
| Olivier, M | 1 |
| Oliveux, A | 1 |
| Masson, JC | 1 |
| Dufour, A | 1 |
| Guyen Qui, JL | 1 |
| Kalogjera, V | 1 |
| Mayer, G | 1 |
| Bollack, C | 1 |
| Djulbegovic, B | 1 |
| Marasa, M | 1 |
| Pesto, A | 1 |
| Kushner, GM | 1 |
| Hadley, T | 1 |
| Joseph, G | 1 |
| Goldsmith, G | 1 |
| Medina Pérez, A | 1 |
| De las Nieves, MA | 1 |
| Vinckier, F | 1 |
| Vermylen, J | 1 |
| Kasper, CK | 1 |
| Dietrich, SL | 1 |
| Ambriz, R | 1 |
| Pizzuto, J | 1 |
| Guillen, C | 1 |
3 reviews available for aminocaproic acid and Hemophilia B
| Article | Year |
|---|---|
Treatment for preventing bleeding in people with haemophilia or other congenital bleeding disorders undergoing surgery.
Topics: Aminocaproic Acid; Antifibrinolytic Agents; Blood Loss, Surgical; Factor VIIa; Hemophilia A; Hemophi | 2015 |
Antifibrinolytic therapy for preventing oral bleeding in patients with haemophilia or Von Willebrand disease undergoing minor oral surgery or dental extractions.
Topics: Aminocaproic Acid; Antifibrinolytic Agents; Blood Loss, Surgical; Factor IX; Factor VIII; Hemophilia | 2015 |
Comprehensive management of haemophilia.
Topics: Aminocaproic Acid; Analgesics; Animals; Anti-Inflammatory Agents; Arthritis; Blood Coagulation Facto | 1985 |
2 trials available for aminocaproic acid and Hemophilia B
| Article | Year |
|---|---|
Ineffectiveness of prophylactic epsilon aminocaproic acid in severe hemophilia.
Topics: Adolescent; Adult; Aminocaproic Acid; Blood Component Transfusion; Child; Child, Preschool; Double-B | 1965 |
Safety and efficacy of purified factor IX concentrate and antifibrinolytic agents for dental extractions in hemophilia B.
Topics: Adult; Aminocaproic Acid; Antifibrinolytic Agents; Factor IX; Hemophilia B; Hemorrhage; Humans; Midd | 1996 |
9 other studies available for aminocaproic acid and Hemophilia B
| Article | Year |
|---|---|
How we treat: patients with haemophilia undergoing screening colonoscopy.
Topics: Aminocaproic Acid; Antifibrinolytic Agents; Colonoscopy; Factor IX; Hemophilia A; Hemophilia B; Huma | 2010 |
HAEMATURIA IN A HAEMOPHILIAC TREATED WITH E-AMINOCAPROIC ACID.
Topics: Aminocaproates; Aminocaproic Acid; Blood Platelet Disorders; Blood Transfusion; Drug Therapy; Hematu | 1965 |
Role of epsilon amino caproic acid in the management of haemophilic patients with inhibitors.
Topics: Adolescent; Adult; Aminocaproic Acid; Antifibrinolytic Agents; Child; Factor VIII; Hemophilia A; Hem | 2004 |
Recurrent bleeding following traumatic hyphema due to mild hemophilia B (Christmas disease).
Topics: Aminocaproic Acid; Anterior Eye Segment; Antifibrinolytic Agents; Child; Eye Injuries; Hemophilia B; | 2007 |
[Dental treatment of a hemophilic patient].
Topics: Aminocaproic Acid; Child, Preschool; Dental Care; Factor VIII; Hemophilia A; Hemophilia B; Humans; L | 1981 |
[Heavy haematuria as the presentation of attenuated haemophilia B (author's transl)].
Topics: Adult; Aminocaproic Acid; Cystitis; Eosinophils; Factor IX; Hematuria; Hemophilia B; Humans; Male; U | 1980 |
[Antifibrinolytics as a treatment for severe factor XI deficiency in laryngeal surgery].
Topics: Aminocaproic Acid; Antifibrinolytic Agents; Hemophilia B; Humans; Intraoperative Complications; Lary | 1999 |
Dental extractions in hemophilia: reflections on 10 years' experience.
Topics: Aminocaproic Acid; Bandages; Cellulose, Oxidized; Dental Care for Disabled; Factor IX; Factor VIII; | 1985 |
Danazol in hemophilia.
Topics: Adult; Aminocaproic Acid; Danazol; Fibrinolysis; Hemophilia A; Hemophilia B; Humans; Male; Pregnadie | 1985 |