alanine has been researched along with Hemophilia B in 4 studies
Alanine: A non-essential amino acid that occurs in high levels in its free state in plasma. It is produced from pyruvate by transamination. It is involved in sugar and acid metabolism, increases IMMUNITY, and provides energy for muscle tissue, BRAIN, and the CENTRAL NERVOUS SYSTEM.
alanine : An alpha-amino acid that consists of propionic acid bearing an amino substituent at position 2.
Hemophilia B: A deficiency of blood coagulation factor IX inherited as an X-linked disorder. (Also known as Christmas Disease, after the first patient studied in detail, not the holy day.) Historical and clinical features resemble those in classic hemophilia (HEMOPHILIA A), but patients present with fewer symptoms. Severity of bleeding is usually similar in members of a single family. Many patients are asymptomatic until the hemostatic system is stressed by surgery or trauma. Treatment is similar to that for hemophilia A. (From Cecil Textbook of Medicine, 19th ed, p1008)
| Excerpt | Relevance | Reference |
|---|---|---|
| "The mild form of haemophilia B has been known to be underdiagnosed due to mild clinical symptoms and minimally prolonged activated partial thromboplastin time." | 1.39 | Mild haemophilia B from a novel missense mutation Ser350Ala of the F9 gene. ( Kim, HJ; Kim, SH; Koo, HH; Park, CH; Seo, JY, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (25.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Park, CH | 1 |
| Seo, JY | 1 |
| Kim, SH | 1 |
| Koo, HH | 1 |
| Kim, HJ | 1 |
| Jin, DY | 1 |
| Zhang, TP | 1 |
| Gui, T | 1 |
| Stafford, DW | 1 |
| Monahan, PE | 1 |
| Maekawa, H | 1 |
| Sugo, T | 1 |
| Yamashita, N | 1 |
| Kamiya, K | 1 |
| Umeyama, H | 1 |
| Miura, N | 1 |
| Naka, H | 1 |
| Nishimura, T | 1 |
| Yoshioka, A | 2 |
| Matsuda, M | 1 |
| Sugimoto, M | 1 |
| Miyata, T | 1 |
| Kawabata, S | 1 |
| Fukui, H | 1 |
| Takahashi, H | 1 |
| Iwanaga, S | 1 |
4 other studies available for alanine and Hemophilia B
| Article | Year |
|---|---|
Mild haemophilia B from a novel missense mutation Ser350Ala of the F9 gene.
Topics: Alanine; Amino Acid Sequence; Child, Preschool; Factor IX; Female; Hemizygote; Hemophilia B; Heteroz | 2013 |
Creation of a mouse expressing defective human factor IX.
Topics: Alanine; Animals; Antibodies; Antigens; Blood Coagulation; Cell Line; Disease Models, Animal; DNA; F | 2004 |
Molecular defect in factor IX Tokyo: substitution of valine-182 by alanine at position P2' in the second cleavage site by factor XIa resulting in impaired activation.
Topics: Adolescent; Alanine; Base Sequence; Blood Coagulation; Computer Simulation; Factor IX; Factor XIa; H | 1993 |
Blood clotting factor IX Niigata: substitution of alanine-390 by valine in the catalytic domain.
Topics: Alanine; Amino Acid Sequence; Binding Sites; Factor IX; Hemophilia B; Humans; Molecular Sequence Dat | 1988 |