prednisone has been researched along with Hemophilia B in 12 studies
Prednisone: A synthetic anti-inflammatory glucocorticoid derived from CORTISONE. It is biologically inert and converted to PREDNISOLONE in the liver.
prednisone : A synthetic glucocorticoid drug that is particularly effective as an immunosuppressant, and affects virtually all of the immune system. Prednisone is a prodrug that is converted by the liver into prednisolone (a beta-hydroxy group instead of the oxo group at position 11), which is the active drug and also a steroid.
Hemophilia B: A deficiency of blood coagulation factor IX inherited as an X-linked disorder. (Also known as Christmas Disease, after the first patient studied in detail, not the holy day.) Historical and clinical features resemble those in classic hemophilia (HEMOPHILIA A), but patients present with fewer symptoms. Severity of bleeding is usually similar in members of a single family. Many patients are asymptomatic until the hemostatic system is stressed by surgery or trauma. Treatment is similar to that for hemophilia A. (From Cecil Textbook of Medicine, 19th ed, p1008)
| Excerpt | Relevance | Reference |
|---|---|---|
| " Amelioration of proteinuria and the plasma coagulation defect followed therapy with corticosteroids and azathioprine." | 3.65 | Factor IX deficiency in the nephrotic syndrome: studies with prothrombin complex concentrate. ( Natelson, EA; Rahman, F; Zanger, B, 1975) |
| "A rare case of a patient with Sjogren syndrome and spontaneously acquired inhibitors of both factor VIII and factor IX is reported." | 1.34 | Combined factor VIII and IX inhibitors in a non-haemophilic patient: successful treatment with immunosuppressive drugs. ( Carmassi, F; De Giorgi, A; De Negri, F; Giannarelli, C, 2007) |
| "Eleven hemophiliacs with chronic liver disease were studied prospectively for 6 yr, with liver function tests and liver biopsies carried out at intervals of 3 yr." | 1.26 | Nonprogressive course of non-A, non-B chronic hepatitis in multitransfused hemophiliacs. ( Colombo, M; Mannucci, PM; Rizzetto, M, 1982) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (83.33) | 18.7374 |
| 1990's | 1 (8.33) | 18.2507 |
| 2000's | 1 (8.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| KOZINN, PJ | 1 |
| RITZ, ND | 1 |
| MOSS, AH | 1 |
| KAUFMAN, A | 1 |
| Carmassi, F | 1 |
| Giannarelli, C | 1 |
| De Giorgi, A | 1 |
| De Negri, F | 1 |
| Mannucci, PM | 1 |
| Colombo, M | 1 |
| Rizzetto, M | 1 |
| Rodríguez Cuartero, A | 1 |
| González Martínez, F | 1 |
| Salas Galán, A | 1 |
| Ramsay, NK | 1 |
| Coccia, PF | 1 |
| Krivit, W | 2 |
| Nesbit, ME | 1 |
| Edson, JR | 2 |
| Miller, K | 1 |
| Neely, JE | 1 |
| Rahman, F | 1 |
| Zanger, B | 1 |
| Natelson, EA | 2 |
| Ozsoylu, S | 1 |
| Ozer, FL | 1 |
| Rainsford, SG | 1 |
| Hall, A | 1 |
| Kisker, CT | 1 |
| Burke, C | 1 |
| Banda, R | 1 |
| Follana, R | 1 |
| Moutaffian, JJ | 1 |
| Delboy, C | 1 |
| Olmer, J | 1 |
| Lynch, EC | 1 |
| Hettig, RA | 1 |
| Alfrey, CP | 1 |
1 trial available for prednisone and Hemophilia B
| Article | Year |
|---|---|
Double-blind studies on the use of steroids in the treatment of acute hemarthrosis in patients with hemophilia.
Topics: Acute Disease; Child; Clinical Trials as Topic; Factor VIII; Hemarthrosis; Hemophilia A; Hemophilia | 1970 |
11 other studies available for prednisone and Hemophilia B
| Article | Year |
|---|---|
MASSIVE HEMORRHAGE--SCALPS OF NEWBORN INFANTS.
Topics: Anemia; Exchange Transfusion, Whole Blood; Factor VII Deficiency; Factor VIII; Hemophilia B; Hemorrh | 1964 |
Combined factor VIII and IX inhibitors in a non-haemophilic patient: successful treatment with immunosuppressive drugs.
Topics: Blood Coagulation Disorders; Blood Coagulation Factor Inhibitors; Factor IX; Factor VIII; Hemophilia | 2007 |
Nonprogressive course of non-A, non-B chronic hepatitis in multitransfused hemophiliacs.
Topics: Adolescent; Adult; Aspartate Aminotransferases; Child; Chronic Disease; Factor IX; Factor VIII; Foll | 1982 |
[Ulcerative colitis and hemophilia B].
Topics: Adult; Anti-Inflammatory Agents; Blood Transfusion; Colitis, Ulcerative; Danazol; Estrogen Antagonis | 1997 |
The effect of L-asparaginase of plasma coagulation factors in acute lymphoblastic leukemia.
Topics: Afibrinogenemia; Asparaginase; Blood Coagulation Disorders; Child; Factor XI Deficiency; Hemophilia | 1977 |
Spontaneously acquired factor IX inhibitor in a nonhemophiliac child.
Topics: Blood Coagulation; Child, Preschool; Cyclophosphamide; Ecchymosis; Exchange Transfusion, Whole Blood | 1978 |
Factor IX deficiency in the nephrotic syndrome: studies with prothrombin complex concentrate.
Topics: Azathioprine; Coagulants; Factor X; Female; Hemophilia B; Humans; Hypertension; Middle Aged; Nephrot | 1975 |
Acquired factor IX deficiency. A report of two cases.
Topics: Adolescent; Adult; Anticoagulants; Blood Coagulation Tests; Capillary Fragility; Factor IX; Female; | 1973 |
A three-year study of adolescent boys suffering from haemophilia and allied disorders.
Topics: Adolescent; Blood Transfusion; Factor IX; Factor VIII; Hematuria; Hemophilia A; Hemophilia B; Hemorr | 1973 |
[The problem of female hemophilia. Evolution of ideas and current concepts. Apropos of a case].
Topics: Adult; Diagnosis, Differential; Factor IX; Factor VIII; Female; Hemophilia A; Hemophilia B; Hemorrha | 1972 |
Acquired factor IX deficiency in the nephrotic syndrome.
Topics: Adolescent; Anticoagulants; Blood Coagulation Disorders; Blood Coagulation Tests; Factor IX; Furosem | 1970 |