tranexamic acid has been researched along with Hemophilia B in 19 studies
Tranexamic Acid: Antifibrinolytic hemostatic used in severe hemorrhage.
Hemophilia B: A deficiency of blood coagulation factor IX inherited as an X-linked disorder. (Also known as Christmas Disease, after the first patient studied in detail, not the holy day.) Historical and clinical features resemble those in classic hemophilia (HEMOPHILIA A), but patients present with fewer symptoms. Severity of bleeding is usually similar in members of a single family. Many patients are asymptomatic until the hemostatic system is stressed by surgery or trauma. Treatment is similar to that for hemophilia A. (From Cecil Textbook of Medicine, 19th ed, p1008)
| Excerpt | Relevance | Reference |
|---|---|---|
| "The use of rFIX, rFVIIa, erythropoetin, iron, and tranexamic acid before, during and after scoliosis surgery may be a viable and safe option for hemophilia patients with inhibitors, who refuse blood products." | 3.74 | [A Jehovah's Witness child with hemophilia B and factor IX inhibitors undergoing scoliosis surgery]. ( Ansermino, M; Chau, A; Purdy, R; Tredwell, S; Wu, J, 2008) |
| "The bleeding was effectively controlled within 1 to 48 h in five of nine bleeding episodes." | 2.69 | Controlling acute bleeding episodes with recombinant factor VIIa in haemophiliacs with inhibitor: continuous infusion and bolus injection. ( Angchaisuksiri, P; Chuansumrit, A; Hathirat, P; Isarangkura, P; Jorgensen, LN; Sriudomporn, N; Tanpowpong, K, 2000) |
| "In people with haemophilia or other congenital bleeding disorders undergoing surgical interventions, haemostatic treatment is needed in order to correct the underlying coagulation abnormalities and minimise the bleeding risk." | 2.52 | Treatment for preventing bleeding in people with haemophilia or other congenital bleeding disorders undergoing surgery. ( Coppola, A; Di Minno, MN; Tufano, A; Windyga, J; Yeung, C, 2015) |
| "Haemophilia B is an inherited bleeding disorder associated with a deficiency of coagulation factor IX." | 2.43 | Haemophilia B: Christmas disease. ( Giangrande, P, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (26.32) | 18.7374 |
| 1990's | 1 (5.26) | 18.2507 |
| 2000's | 6 (31.58) | 29.6817 |
| 2010's | 6 (31.58) | 24.3611 |
| 2020's | 1 (5.26) | 2.80 |
| Authors | Studies |
|---|---|
| Marlière, C | 1 |
| Maindiaux, L | 1 |
| Lambert, C | 1 |
| Hermans, C | 1 |
| Lewandowski, B | 1 |
| Wojnar, J | 1 |
| Brodowski, R | 1 |
| Mucha, M | 1 |
| Czenczek-Lewandowska, E | 1 |
| Brzęcka, D | 1 |
| Coppola, A | 1 |
| Windyga, J | 1 |
| Tufano, A | 1 |
| Yeung, C | 1 |
| Di Minno, MN | 1 |
| van Galen, KP | 1 |
| Engelen, ET | 1 |
| Mauser-Bunschoten, EP | 1 |
| van Es, RJ | 1 |
| Schutgens, RE | 1 |
| Yilmaz, D | 1 |
| Akin, M | 1 |
| Ay, Y | 1 |
| Balkan, C | 1 |
| Celik, A | 1 |
| Ergün, O | 1 |
| Kavakli, K | 1 |
| Troccola, A | 1 |
| Maruccia, M | 1 |
| Zampieri, AE | 1 |
| Dessy, LA | 1 |
| Hewson, ID | 1 |
| Makhmaloaf, P | 1 |
| O'Connell, NM | 1 |
| Giangrande, P | 1 |
| Sarris, I | 1 |
| Arafa, A | 1 |
| Konaris, L | 1 |
| Kadir, RA | 1 |
| Chau, A | 1 |
| Wu, J | 1 |
| Ansermino, M | 1 |
| Tredwell, S | 1 |
| Purdy, R | 1 |
| Djulbegovic, B | 1 |
| Hannan, MM | 1 |
| Bergman, GE | 1 |
| Chuansumrit, A | 1 |
| Isarangkura, P | 1 |
| Angchaisuksiri, P | 1 |
| Sriudomporn, N | 1 |
| Tanpowpong, K | 1 |
| Hathirat, P | 1 |
| Jorgensen, LN | 1 |
| Stubbs, M | 1 |
| Lloyd, J | 1 |
| Black, EA | 1 |
| Prentice, CR | 1 |
| Sindet-Pedersen, S | 2 |
| Stenbjerg, S | 2 |
| Ingerslev, J | 1 |
| Vinckier, F | 1 |
| Vermylen, J | 1 |
5 reviews available for tranexamic acid and Hemophilia B
| Article | Year |
|---|---|
Treatment for preventing bleeding in people with haemophilia or other congenital bleeding disorders undergoing surgery.
Topics: Aminocaproic Acid; Antifibrinolytic Agents; Blood Loss, Surgical; Factor VIIa; Hemophilia A; Hemophi | 2015 |
Antifibrinolytic therapy for preventing oral bleeding in patients with haemophilia or Von Willebrand disease undergoing minor oral surgery or dental extractions.
Topics: Aminocaproic Acid; Antifibrinolytic Agents; Blood Loss, Surgical; Factor IX; Factor VIII; Hemophilia | 2015 |
Factor XI deficiency--from molecular genetics to clinical management.
Topics: Amino Acid Sequence; Arabs; Factor IX; Factor VII; Factor VIIa; Founder Effect; Gene Expression Regu | 2003 |
Haemophilia B: Christmas disease.
Topics: Antifibrinolytic Agents; Autoantibodies; Clinical Trials as Topic; Developing Countries; Factor IX; | 2005 |
Indications for antifibrinolytic therapy.
Topics: Aminocaproates; Antifibrinolytic Agents; Aprotinin; Blood Coagulation Disorders; Disseminated Intrav | 1975 |
3 trials available for tranexamic acid and Hemophilia B
| Article | Year |
|---|---|
Concomitant treatment with factor IX concentrates and antifibrinolytics in hemophilia B.
Topics: Aminocaproates; Antifibrinolytic Agents; Blood Coagulation Factors; Drug Therapy, Combination; Hemat | 1995 |
Controlling acute bleeding episodes with recombinant factor VIIa in haemophiliacs with inhibitor: continuous infusion and bolus injection.
Topics: Adult; Anti-Inflammatory Agents; Antifibrinolytic Agents; Child, Preschool; Disease Management; Fact | 2000 |
Re: tranexamic acid and bleeding: a double-blind cross-over study on three brothers with Christmas disease (factor IX deficiency).
Topics: Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Hemophilia B; Humans; Male; Tranexamic Acid | 1976 |
11 other studies available for tranexamic acid and Hemophilia B
| Article | Year |
|---|---|
EHL-FIX in haemophilia B carriers with FIX deficiency.
Topics: Adolescent; Adult; Antifibrinolytic Agents; Child; Factor IX; Female; Half-Life; Hemophilia A; Hemop | 2020 |
Dental extractions in patients with mild hemophilia A and hemophilia B and von Willebrand disease without clotting factor supplementation.
Topics: Adult; Antifibrinolytic Agents; Blood Coagulation Disorders, Inherited; Dental Caries; Female; Hemop | 2018 |
A single centre experience in circumcision of haemophilia patients: Izmir protocol.
Topics: Antifibrinolytic Agents; Blood Loss, Surgical; Child; Child, Preschool; Circumcision, Male; Factor I | 2010 |
Management of second-degree burn induced by dry ice in a Christmas disease patient.
Topics: Administration, Oral; Adult; Antifibrinolytic Agents; Bandages; Burns; Dry Ice; Factor IX; Hemophili | 2010 |
Management of third molar removal with a single dose of recombinant Factor IX (BeneFIX) and local measures in severe haemophilia B.
Topics: Adult; Antifibrinolytic Agents; Cellulose, Oxidized; Coagulants; Factor IX; Follow-Up Studies; Hemop | 2010 |
Topical use of tranexamic acid to control perioperative local bleeding in gynaecology patients with clotting disorders: two cases.
Topics: Administration, Oral; Administration, Topical; Aged; Antifibrinolytic Agents; Blood Coagulation Diso | 2007 |
[A Jehovah's Witness child with hemophilia B and factor IX inhibitors undergoing scoliosis surgery].
Topics: Adolescent; Antifibrinolytic Agents; Blood Loss, Surgical; Dietary Supplements; Epoetin Alfa; Erythr | 2008 |
A protocol for the dental management of von Willebrand's disease, haemophilia A and haemophilia B.
Topics: Adolescent; Adult; Aged; Antifibrinolytic Agents; Clinical Protocols; Deamino Arginine Vasopressin; | 2001 |
Effect of local antifibrinolytic treatment with tranexamic acid in hemophiliacs undergoing oral surgery.
Topics: Administration, Oral; Administration, Topical; Cyclohexanecarboxylic Acids; Dental Care for Disabled | 1986 |
Control of gingival hemorrhage in hemophilic patients by inhibition of fibrinolysis with tranexamic acid.
Topics: Administration, Oral; Adolescent; Adult; Child; Child, Preschool; Cyclohexanecarboxylic Acids; Fibri | 1988 |
Dental extractions in hemophilia: reflections on 10 years' experience.
Topics: Aminocaproic Acid; Bandages; Cellulose, Oxidized; Dental Care for Disabled; Factor IX; Factor VIII; | 1985 |