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aspirin and Hemophilia B

aspirin has been researched along with Hemophilia B in 9 studies

Aspirin: The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
acetylsalicylate : A benzoate that is the conjugate base of acetylsalicylic acid, arising from deprotonation of the carboxy group.
acetylsalicylic acid : A member of the class of benzoic acids that is salicylic acid in which the hydrogen that is attached to the phenolic hydroxy group has been replaced by an acetoxy group. A non-steroidal anti-inflammatory drug with cyclooxygenase inhibitor activity.

Hemophilia B: A deficiency of blood coagulation factor IX inherited as an X-linked disorder. (Also known as Christmas Disease, after the first patient studied in detail, not the holy day.) Historical and clinical features resemble those in classic hemophilia (HEMOPHILIA A), but patients present with fewer symptoms. Severity of bleeding is usually similar in members of a single family. Many patients are asymptomatic until the hemostatic system is stressed by surgery or trauma. Treatment is similar to that for hemophilia A. (From Cecil Textbook of Medicine, 19th ed, p1008)

Research Excerpts

ExcerptRelevanceReference
"The six patients with Haemophilia A ranged in severity from moderately to mildly affected."2.69Cardiac surgery and catheterization in patients with haemophilia. ( MacKinlay, N; Renisson, F; Rickard, K; Taper, J, 2000)
"Of 49 patients with hemophilia A or B, who had not received replacement transfusions for at least 72 hours, ten were demonstrated to have a prolonged value for the bleeding time."1.26Prolonged bleeding time in children and young adults with hemophilia. ( Buchanan, GR; Holtkamp, CA, 1980)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19907 (77.78)18.7374
1990's0 (0.00)18.2507
2000's2 (22.22)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Wang, X1
Cheng, Q1
Xu, L1
Feuerstein, GZ1
Hsu, MY1
Smith, PL1
Seiffert, DA1
Schumacher, WA1
Ogletree, ML1
Gailani, D1
Buchanan, GR1
Holtkamp, CA1
MacKinlay, N1
Taper, J1
Renisson, F1
Rickard, K1
Rosenstein, R1
Zacharski, LR1
Green, D1
Dube, B1
Chawla, SC1
Vaish, SK1
Somani, PN1
Srivastava, PK1
Quick, AJ1
Kaneshiro, MM1
Mielke, CH1
Kasper, CK1
Rapaport, SI1
Toskes, PP1
Wagger, GM1
Raskin, HF1
Attar, S1

Reviews

1 review available for aspirin and Hemophilia B

ArticleYear
Hemophilia.
    Postgraduate medicine, 1974, Volume: 55, Issue:5

    Topics: Aminocaproates; Aspirin; Factor IX; Factor VIII; Hemophilia A; Hemophilia B; Humans; Liver; Spleen

1974

Trials

1 trial available for aspirin and Hemophilia B

ArticleYear
Cardiac surgery and catheterization in patients with haemophilia.
    Haemophilia : the official journal of the World Federation of Hemophilia, 2000, Volume: 6, Issue:2

    Topics: Adolescent; Adult; Aged; Aortic Valve; Aspirin; Cardiac Catheterization; Coronary Angiography; Coron

2000

Other Studies

7 other studies available for aspirin and Hemophilia B

ArticleYear
Effects of factor IX or factor XI deficiency on ferric chloride-induced carotid artery occlusion in mice.
    Journal of thrombosis and haemostasis : JTH, 2005, Volume: 3, Issue:4

    Topics: Animals; Arteries; Aspirin; Bleeding Time; Blood Flow Velocity; Carotid Arteries; Carotid Artery Dis

2005
Prolonged bleeding time in children and young adults with hemophilia.
    Pediatrics, 1980, Volume: 66, Issue:6

    Topics: Adolescent; Adult; Aspirin; Bleeding Time; Blood Platelets; Child; Child, Preschool; Hemophilia A; H

1980
The diagnostic value of the aspirin tolerance test.
    Thrombosis research, 1979, Volume: 16, Issue:1-2

    Topics: Aspirin; Bleeding Time; Blood Platelet Disorders; Drug Tolerance; Factor XI Deficiency; Hemophilia B

1979
Consumption coagulopathy following haemolytic crisis in glucose-6-phosphate dehydrogenase deficient subjects.
    The Journal of the Association of Physicians of India, 1972, Volume: 20, Issue:6

    Topics: Adolescent; Adult; Aspirin; Disseminated Intravascular Coagulation; Glucosephosphate Dehydrogenase D

1972
Acetylsalicylic acid as a diagnostic aid in hemostasis.
    The American journal of the medical sciences, 1967, Volume: 254, Issue:4

    Topics: Adolescent; Adult; Aspirin; Blood Coagulation Tests; Child; Female; Hemophilia A; Hemophilia B; Huma

1967
Bleeding time after aspirin in disorders of intrinsic clotting.
    The New England journal of medicine, 1969, Nov-06, Volume: 281, Issue:19

    Topics: Aspirin; Blood Coagulation; Blood Coagulation Tests; Blood Transfusion; Factor VIII; Factor XI Defic

1969
Coagulation defects in undiagnosed recurrent gastrointestinal bleeding.
    Annals of surgery, 1970, Volume: 172, Issue:1

    Topics: Adult; Aged; Aspirin; Blood Coagulation Disorders; Blood Coagulation Factors; Blood Coagulation Test

1970