chlorine has been researched along with Hemophilia B in 4 studies
chloride : A halide anion formed when chlorine picks up an electron to form an an anion.
Hemophilia B: A deficiency of blood coagulation factor IX inherited as an X-linked disorder. (Also known as Christmas Disease, after the first patient studied in detail, not the holy day.) Historical and clinical features resemble those in classic hemophilia (HEMOPHILIA A), but patients present with fewer symptoms. Severity of bleeding is usually similar in members of a single family. Many patients are asymptomatic until the hemostatic system is stressed by surgery or trauma. Treatment is similar to that for hemophilia A. (From Cecil Textbook of Medicine, 19th ed, p1008)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Protein infusion of FIX-Triple into haemophilia B mice was not thrombogenic, even at a dose of 13-fold higher than FIX-WT." | 1.36 | FIX-Triple, a gain-of-function factor IX variant, improves haemostasis in mouse models without increased risk of thrombosis. ( Kao, CY; Kao, JT; Lin, CN; Lin, SW; Shi, GY; Tao, MH; Wu, HL; Yang, YL; Yu, IS, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 3 (75.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kastetter, B | 1 |
| Matrai, AB | 1 |
| Cooley, BC | 1 |
| Metzger, JM | 1 |
| Tadin-Strapps, M | 1 |
| Thankappan, A | 1 |
| Strapps, WR | 1 |
| DiPietro, M | 1 |
| Leander, K | 1 |
| Zhang, Z | 1 |
| Shin, MK | 1 |
| Levorse, J | 1 |
| Desai, K | 1 |
| Xu, Y | 1 |
| Lai, K | 1 |
| Wu, W | 1 |
| Chen, Z | 1 |
| Cai, TQ | 1 |
| Jochnowitz, N | 1 |
| Bentley, R | 1 |
| Hoos, L | 1 |
| Zhou, Y | 1 |
| Sepp-Lorenzino, L | 1 |
| Seiffert, D | 1 |
| Andre, P | 1 |
| Kao, CY | 1 |
| Lin, CN | 1 |
| Yu, IS | 1 |
| Tao, MH | 1 |
| Wu, HL | 1 |
| Shi, GY | 1 |
| Yang, YL | 1 |
| Kao, JT | 1 |
| Lin, SW | 1 |
| Wang, X | 1 |
| Cheng, Q | 1 |
| Xu, L | 1 |
| Feuerstein, GZ | 1 |
| Hsu, MY | 1 |
| Smith, PL | 1 |
| Seiffert, DA | 1 |
| Schumacher, WA | 1 |
| Ogletree, ML | 1 |
| Gailani, D | 1 |
4 other studies available for chlorine and Hemophilia B
| Article | Year |
|---|---|
Optimizing outcome measurement with murine ferric chloride-induced thrombosis.
Topics: Animals; Carotid Arteries; Chlorides; Factor IX; Ferric Compounds; Hemophilia B; Mice; Mice, Knockou | 2018 |
Titrating haemophilia B phenotypes using siRNA strategy: evidence that antithrombotic activity is separated from bleeding liability.
Topics: Animals; Cell Line; Chlorides; Disease Models, Animal; Factor IX; Ferric Compounds; Gene Expression | 2015 |
FIX-Triple, a gain-of-function factor IX variant, improves haemostasis in mouse models without increased risk of thrombosis.
Topics: Animals; Chlorides; Coagulants; Dependovirus; Disease Models, Animal; Dose-Response Relationship, Dr | 2010 |
Effects of factor IX or factor XI deficiency on ferric chloride-induced carotid artery occlusion in mice.
Topics: Animals; Arteries; Aspirin; Bleeding Time; Blood Flow Velocity; Carotid Arteries; Carotid Artery Dis | 2005 |