Conditions > Angioma, Cavernous
Page last updated: 2024-09-28

Angioma, Cavernous

A vascular anomaly that is a collection of tortuous BLOOD VESSELS and connective tissue. This tumor-like mass with the large vascular space is filled with blood and usually appears as a strawberry-like lesion in the subcutaneous areas of the face, extremities, or other regions of the body including the central nervous system.

Synonyms(5)

Synonym
Angioma, Cavernous
Hemangioma, Cavernous
Strawberry Hemangiomas
Cavernous Angioma
Cavernous Hemangioma

Research Excerpts

Overview

ExcerptReference
"Although cavernous hemangioma is the most common benign tumor of the liver, controversy persists regarding diagnosis and management of these lesions."( DuPre, CT; Fincher, RM, 1992)
"Cavernous hemangioma is most common in or beneath the skin of the face, neck, and extremities and sometimes occurs in the scalp."( Enomoto, T; Fujimori, H; Nose, T; Yanaka, K, 1992)
"Cavernous hemangiomas are the commonest benign tumors of the liver."( Calbiani, B; Ferrarese, A; Leonardi, F; Ugolotti, G, 1988)
"Cavernous hemangiomas are the most common benign tumors of the liver, which are now seen more often thanks to common use of newer imaging techniques."( Takagi, H, 1985)
"Hepatic cavernous hemangiomas are benign tumors of the liver that are often an incidental finding."( Allison, JR; McMurray, JM; Moinuddin, M; Montgomery, JH; Rockett, JF, 1985)
"Cavernous hemangiomas are the most common benign tumors of the liver."( English, RJ; Holman, BL; Tumeh, SS, 1985)
"Cavernous angiomas are vascular malformations that cause neurodegeneration and symptoms including epileptiform seizures, headache, and motor deficits."( Hamberger, A; Mozzi, R; Nyström, B; Rydenhag, B; van Gelder, N; von Essen, C, 1996)
"Cavernous hemangioma is the most common benign tumor of the liver, the organ in which these lesions are most often present."( Artigas, JM; Baringo, T; Ceballos, C; Córdoba, E; Isla, C; Miravete, MI, 1997)
"Cavernous hemangiomas are the most common benign tumours of the liver, being the liver the most frequent organ affected by this lesions."( Artigas, JM; Baringo, T; Ceballos, C; Córdoba, E; Isla, C; Miravete, MI, 1997)
"Surgery of cavernous angiomas is often proposed due to the epileptogenic and hemorrhagic potential of this lesion."( Cinotti, L; Fischer, G; Froment, JC; Gogoleva, SM; Jouvet, A; Mauguière, F; Ryvlin, P; Saint Pierre, G; Sindou, M; Veyre, L, 1997)
"Cavernous hemangiomas are commonly seen in extremities, neck, face and sometimes scalp, cutaneous or subcutaneous in localization."( Aydin, IH; Kadioğlu, HH; Kayaoğlu, CR; Oztürk, M; Suma, S; Takçi, E; Tüzün, Y, 1998)
"Extra-axial cavernous hemangiomas are rare and have a propensity to develop within the cavernous sinus."( Hang, C; Liu, C; Pan, Y; Shi, J; Wang, H; Zhang, Z, 1999)
"The cavernous hemangioma is the most common benign orbital tumor in adults."( Capakaya, G; Durak, H; Durak, I; Sayit, E; Yilmaz, M, 2001)
"Cavernous hemangiomas are also malformations that demonstrate direct low flow through the lesion."( Rootman, J, 2003)
"Cavernous hemangioma is a benign orbital extraocular vascular lesion consisting of large dilated venous channels with fibrous, well-delineated capsule and hemosiderin deposition."( Gallucci, M; Limbucci, N; Paonessa, A, 2008)
"Cavernous hemangioma is a rare bony tumor that should be considered in the differential diagnosis of skull tumors."( Akai, T; Iizuka, H; Itou, S; Masuoka, T; Oohashi, M; Sasagawa, Y; Yamamoto, K, 2009)
"Intraosseous cavernous hemangioma is rarely located in the calvarium."( Custoza, E; Giezek, F; Jouandeau, V; Magnies, M, 2009)
"Cavernous hemangioma is vascular malformation with developmental aberrations."( Grau, GE; Liu, HL; Lou, JN; Wu, LQ; Xin, YL; Ye, LY; Zhang, WJ, 2009)
"Cavernous hemangiomas are the most frequent neoplasms of the liver and in routine clinical practice they often need to be differentiated from malignant tumors and other benign focal lesions."( Drobinska-Jurowiecka, A; Izycka-Swieszewska, E; Markiet, K; Nowicki, T; Studniarek, M; Szarmach, A; Szurowska, E; Wypych, J, 2011)
"Orbital cavernous hemangioma is very common in adults, but spontaneous bleeding is extremely rare relative to intracranial cavernous hemangiomas."( Kitagawa, T; Miyaoka, R; Nakano, Y; Nishizawa, S; Saito, T; Takahashi, M; Ueta, K; Yamamoto, J, 2012)
"Cavernous hemangioma is the most frequent benign orbital tumor in adults."( Aymard, PA; Galatoire, O; Jacomet, PV; Langlois, B; Morax, S; Putterman, M, 2013)
"Cavernous hemangiomas are the most common orbital tumors in adults."( Chhabra, N; Fay, A; Metson, R; Wu, AW, 2014)
"An orbital cavernous hemangioma is composed of large, ectatic, endothelium-lined, blood-filled spaces."( Li, Y; Yan, J, 2014)
"Orbital cavernous hemangiomas are the most common primary benign orbital tumors in adults."( Gioacchini, FM; Pasquini, E; Re, M; Tarchini, P, 2016)
"Cavernous hemangioma is the most common orbital tumor in adult."( Bhattacharjee, H; Bhattacharjee, K; Das, D; Deka, A; Deka, P; Kapoor, D; Koul, A; Misra, DK, 2016)
"Cavernous hemangiomas are the most common benign orbital tumors in the orbit, but radiological differentiation from other solitary orbital masses can still be challenging at times."( Kim, YD; Lee, JH; Woo, KI; Young, SM, 2018)
"The treatment of cavernous hemangiomas is controversial."( Huang, G; Lin, H; Lin, ZY; Wang, LH; Wang, WY, 2019)
"Third ventricular cavernous angioma is considered in the differential diagnosis of chiasmal syndrome."( Chin, S; Ishida, S; Ishijima, K; Nozaki, M; Shinmei, Y; Yamaguchi, S, 2019)
"Craniorbital cavernous hemangioma is uncommon, however within the cranium, they can lead to numerous complications particularly if affecting the visual apparatus."( Akter, F; Li, X; Li, Y; Liu, R; Qin, L; Qin, X; Wu, S; Xie, Q; Yang, H; Zhang, G, 2020)
"Cavernous hemangiomas are congenital hamartomatous lesions that originate from mesodermal tissue composed of dilated blood vessels."( Abreu, P; Assef, MS; Ferreira, FG; Ferreira, R; Park, JH; Ribeiro, MA; Szutan, LA, 2021)

Treatment

ExcerptReference
"30 patients including 24 cavernous hemangiomas and 6 mixed hemangiomas were treated with this method."( Zhang, JJ, 1992)
"Cerebral cavernous angioma (cavernoma) has previously been treated by resection for all presentations when surgically resectable."( Churchyard, A; Grainger, K; Khangure, M, 1992)
"Thirteen patients with capillary/cavernous hemangiomas of infancy have been treated with a combination of neodymium: YAG laser photocoagulation plus direct local instillation of steroids."( Apfelberg, DB; Lash, H; Maser, MR; White, DN, 1989)
"Corticosteroid treatment of infant strawberry hemangiomas produced premature regression of growing lesions in patients less than a year of age, but not in patients with cavernous or port-wine hemangiomas."( Pang, CY; Sasaki, GH; Wittliff, JL, 1984)
"8 cases of huge cavernous hemangioma (3 in hand, 2 in lip and buccal region, 1 in perineum and buttock and 2 in frontal region) were treated by retaining copper needles which were inserted into the blood-filled spaces and feeders with satisfactory results."( Wang, D, 1993)
"1993, we have treated 31 patients with cavernous hemangioma using copper needle puncturing."( Cheng, G; Gao, S; Sun, J, 1995)
"Thirty-one patients with subcutaneous cavernous hemangioma were observed by echogram before and after treatment with copper needling."( Gao, S; Yang, J; Zhao, X, 1995)
"The treatment for the cavernous hemangioma and peripheral vascular disorders with copper needles have a commendable result, copper needle retention combined with a direct current has a better result than copper needle retention only."( Chen, ZC; Gao, S; Wang, DM; Wang, YJ, 2006)
"Thirty-nine patients with orbital cavernous hemangiomas were treated with transconjunctival orbitotomy."( Cai, JP; Cheng, JW; Li, Y; Wei, RL, 2008)
"Of the 316 patients with strawberry hemangiomas, the lesion disappeared completely within 3 months after one-time treatment in 259 cases (82%)."( Deng, JL; Lu, JR; Shi, CB; Wang, J; Xu, JL; Yang, WD; Yuan, B, 2012)
"Symptomatic cavernous hemangiomas should be treated."( Bertelmann, E; von Sonnleithner, C; Zorn, M, 2019)
"The treatment of cavernous hemangiomas is controversial."( Huang, G; Lin, H; Lin, ZY; Wang, LH; Wang, WY, 2019)

Research

Studies (710)

TimeframeStudies, This Condition (%)All Conditions %
pre-1990326 (45.92)23.3326
1990's148 (20.85)12.5806
2000's116 (16.34)18.1394
2010's92 (12.96)28.8240
2020's28 (3.94)9.53
DrugIndicatedRelationship StrengthStudiesTrials
gamma-aminobutyric acid0low10
salicylic acid0low210
aminocaproic acid0low10
dimethyl sulfoxide0low10
ethanolamine0low10
glycine0low20
glycerol0low10
carbonic acid0low10
dihydroxyphenylalanine0low10
phytic acid0low10
nitrous oxide0low10
phenol0low10
pyridoxal0low10
pyridoxal phosphate0low10
urea0medium21
1,2-dimethylhydrazine0low10
phenytoin0low40
acetazolamide0low10
albendazole0low10
diatrizoic acid0low40
amitriptyline0low10
amobarbital0low10
aspirin0low30
azathioprine0low10
biperiden0low10
busulfan0low10
carbamazepine0low30
celecoxib0low10
chlorambucil0low10
clonazepam0low10
pentetic acid0low130
dipyridamole0low10
valproic acid0low20
erythrosine0low40
etidronate0medium11
famotidine0low10
fluorouracil0low10
furosemide0low20
gabapentin0low10
gentamicin0low10
hydroxyurea0low20
lidocaine0low10
iodixanol0low10
iofetamine0low10
iohexol0low40
2-propanol0low70
ketamine0low20
lomustine0low10
mepivacaine0low10
mexiletine0low10
midodrine0low10
nafamostat0low10
phenobarbital0low10
prazosin0low10
propofol0low10
propranolol0low150
sulfobromophthalein0low10
ticlopidine0low10
tranexamic acid0low40
urethane0low10
mitomycin0low10
prednisolone0low90
spironolactone0low10
prednisone0low230
idoxuridine0low10
serine0low10
chloramphenicol0low10
ethinyl estradiol0low10
adenosine diphosphate0low20
levodopa0low20
edetic acid0low10
desoxycorticosterone0low10
triaziquone0low10
tryptophan0low10
triamcinolone acetonide0low30
isoprene0low10
methylmethacrylate0low20
methylprednisolone0low70
diatrizoate meglumine0low30
meglumine0medium41
dydrogesterone0low10
perfluorobutane0low10
betamethasone0low30
podophyllotoxin0low10
methamphetamine0low10
perfluoropentane0medium11
methylnitrosourea0low10
bucrylate0low10
durapatite0low10
thorium dioxide0low10
vancomycin0low10
pseudouridine0low10
pimozide0low10
methylprednisolone hemisuccinate0low10
megestrol0low10
carbonates0low10
triamcinolone hexacetonide0low10
enbucrilate0low10
neodymium0low30
platinum0low10
technetium0medium732
terbium0low10
titanium0low20
argon0low60
cadmium0low10
chromium0low10
gadolinium0medium201
xenon0low20
yttrium0low10
barium sulfate0low40
tricalcium phosphate0medium11
radon0low30
chlormerodrin0low10
trolamine salicylate0low20
phenyl acetate0low10
fludrocortisone0low10
etoposide0low10
sq-117250low10
diltiazem0low10
vecuronium bromide0low10
desogestrel0low10
epirubicin0low10
desflurane0low10
propiconazole0medium1172
fomesafen0low10
remifentanil0low20
atorvastatin0medium11
dimethylhydrazines0low10
ortho-cept0low10
metaperiodate0low10
iopamidol0low10
xenon radioisotopes0low10
fluorodeoxyglucose f180low110
nomegestrol0low10
fibrinogen0low70
cobalt0low10
deoxyglucose0low10
gadolinium 1,4,7,10-tetraazacyclododecane-n,n',n'',n'''-tetraacetate0low10
methotrexate0low20
potassium titanylphosphate0low10
technetium tc 99m pentetate0low30
atropine0low10
cortisone0low20
bradykinin0low10
elastin0low10
oxytocin0low10
inositol 3-phosphate0low100
rocuronium0low10
metrizamide0low10
clindamycin0low10
dactinomycin0low10
picibanil0low10
pyrophosphate0low10
polidocanol0low20
iothalamate meglumine0low10
enclomiphene0low10
digoxin0low10
tamoxifen0low10
zinc oxide0low20
bilirubin0low20
vitamin k semiquinone radical0low10
ethamolin0low10
phenylephrine hydrochloride0low220
levetiracetam0low10
aluminum0low10
indium0low10
sulfur0low30
strontium radioisotopes0low10
radium0low120
technetium tc 99m pyrophosphate0low20
gadolinium dtpa0low270
shu 5080low10
technetium tc 99m disofenin0low10
technetium tc 99m mebrofenin0low10
losartan potassium0low20
technetium tc 99m exametazime0low20
indocyanine green0low60
acid phosphatase0low20
bleomycetin0low40
jaw0low10
(dtpa-phe(1))-octreotide0low10
carbetocin0low10
urografin 760low10
sodium pertechnetate tc 99m0low140
sodium ethylxanthate0low20
cardiovascular agents0low10
piperidines0low10
vasoactive intestinal peptide0low10
acenocoumarol0low10
warfarin0low10
n,n'-bis(pyridoxal-5-phosphate)ethylenediamine-n,n'-diacetic acid0low10
zhengguangmycin0medium91
transforming growth factor beta0low10
agar0low10
technetium tc 99m sulfur colloid0low50
gadoxetic acid disodium0low20
vitamin b 120low10
transforming growth factor alpha0low20
technetium tc 99m medronate0low50
sodium morrhuate0low40
thromboplastin0low10
eye0low40
carbidopa0low10
phosphorus radioisotopes0low20

Protein Targets (1,339)

ProteinPotency MeasurementsInhibition MeasurementsActivation MeasurementsDrugs
hypoxia-inducible factor 1 alpha subunit210021
RAR-related orphan receptor gamma460046
GLI family zinc finger 3500050
AR protein640064
aldehyde dehydrogenase 1 family, member A1340034
retinoic acid nuclear receptor alpha variant 1540054
retinoid X nuclear receptor alpha420042
estrogen nuclear receptor alpha680068
peroxisome proliferator-activated receptor delta300030
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a370037
activating transcription factor 6230023
v-jun sarcoma virus 17 oncogene homolog (avian)270027
Histone H2A.x230023
thyroid hormone receptor beta isoform a240024
heat shock protein beta-1210021
nuclear factor erythroid 2-related factor 2 isoform 1490049
lamin isoform A-delta10400040
Voltage-dependent calcium channel gamma-2 subunit280028
Glutamate receptor 2290029
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE270027
Luciferase170017
G170017
peroxisome proliferator activated receptor gamma330033
euchromatic histone-lysine N-methyltransferase 2460046
thyroid stimulating hormone receptor210021
chromobox protein homolog 1280028
parathyroid hormone/parathyroid hormone-related peptide receptor precursor6006
geminin490049
muscleblind-like protein 1 isoform 19009
Interferon beta290029
HLA class I histocompatibility antigen, B alpha chain 170017
Guanine nucleotide-binding protein G4004
Inositol hexakisphosphate kinase 1170017
cytochrome P450 2C9, partial170017
Chain A, TYROSYL-DNA PHOSPHODIESTERASE170017
Chain A, CARBONIC ANHYDRASE II0011
Chain A, CARBONIC ANHYDRASE II0011
Chain A, CARBONIC ANHYDRASE II0011
Chain A, Carbonic Anhydrase Ii0011
Chain A, Carbonic Anhydrase Ii0011
Chain A, Beta-lactamase180018
Chain A, Endochitinase0101
Chain A, Endochitinase0101
Chain A, Endochitinase0101
Chain A, Class Iii Chitinase Chia10101
Chain A, Carbonic anhydrase 130101
Chain A, Carbonic anhydrase II0101
Chain A, Carbonic anhydrase 20101
Chain A, Carbonic anhydrase 20101
Chain A, Carbonic anhydrase 20101
Chain A, Carbonic anhydrase 20101
Chain A, Carbonic anhydrase 20101
Chain A, Carbonic anhydrase 20101
Chain A, Carbonic anhydrase 20101
Chain A, Carbonic anhydrase 20101
Chain A, Carbonic anhydrase 20101
Chain A, Carbonic anhydrase0101
Chain B, Carbonic anhydrase0101
Chain A, Carbonic anhydrase 20101
Carbonic anhydrase 0002
Carbonic anhydrase 0202
thioredoxin reductase260026
GALC protein7007
nuclear receptor subfamily 1, group I, member 3350035
cytochrome P450 family 3 subfamily A polypeptide 4360036
glucocorticoid receptor [Homo sapiens]530053
estrogen-related nuclear receptor alpha520052
Carbonic anhydrase 0202
Carbonic anhydrase 0303
arylsulfatase A150015
Carbonic anhydrase0303
Bloom syndrome protein isoform 1210021
peripheral myelin protein 22260026
survival motor neuron protein isoform d160016
Gamma-aminobutyric acid receptor subunit pi177226
ATP-binding cassette sub-family C member 3039039
Multidrug resistance-associated protein 4039041
Carbonic anhydrase0101
Solute carrier family 22 member 60505
Carbonic anhydrase 1208114
Prolyl endopeptidase0101
Carbonic anhydrase-related protein 110102
Bile salt export pump055055
Glycogen phosphorylase, muscle form0101
Renin0202
Carbonic anhydrase 1018126
Carbonic anhydrase 2019228
Carbonic anhydrase 20202
Cytochrome P450 1A20415
Carbonic anhydrase 307112
Cathepsin B0101
Cytochrome P450 3A4014218
Steryl-sulfatase0101
5-hydroxytryptamine receptor 2C0607
Polyunsaturated fatty acid 5-lipoxygenase0303
Cytochrome P450 2C80303
Cytochrome P450 2D6011112
Cytochrome P450 2A60202
Cytochrome P450 2C9 015116
5-hydroxytryptamine receptor 2A0505
Androgen receptor011012
Gamma-aminobutyric acid receptor subunit beta-1177226
Translocator protein0101
Gamma-aminobutyric acid receptor subunit delta177226
Gamma-aminobutyric acid receptor subunit gamma-2177327
Gamma-aminobutyric acid receptor subunit alpha-5177226
Gamma-aminobutyric acid receptor subunit alpha-3177226
Cannabinoid receptor 10202
Arachidonate 5-lipoxygenase-activating protein0101
Cytochrome P450 2B60516
Carbonic anhydrase 4011116
Carbonic anhydrase 609114
Gamma-aminobutyric acid receptor subunit gamma-1177226
Gamma-aminobutyric acid receptor subunit alpha-2177226
Carbonic anhydrase 5A, mitochondrial0101
Adenosine receptor A10506
Serum paraoxonase/arylesterase 10404
Dipeptidyl peptidase 40001
Gamma-aminobutyric acid receptor subunit alpha-4177226
Gamma-aminobutyric acid receptor subunit gamma-3177226
Endochitinase0101
Gamma-aminobutyric acid receptor subunit alpha-6177226
Adenosine receptor A2a0405
5-hydroxytryptamine receptor 2B0404
Sodium-dependent serotonin transporter0314
Delta-type opioid receptor0303
Cytochrome P450 2C190819
Delta-type opioid receptor0404
Mu-type opioid receptor0404
Carbonic anhydrase 5A, mitochondrial010116
Carbonic anhydrase0507
Kappa-type opioid receptor0101
Carbonic anhydrase 708113
Carbonic anhydrase0101
D(1A) dopamine receptor5106
Corticosteroid 11-beta-dehydrogenase isozyme 10202
Carbonic anhydrase0204
D(2) dopamine receptor0606
Gamma-aminobutyric acid receptor subunit alpha-1179329
Gamma-aminobutyric acid receptor subunit beta-3177226
Gamma-aminobutyric acid receptor subunit beta-2177327
Cholinesterase0303
Carbonic anhydrase 0303
Mu-type opioid receptor0303
Fatty-acid amide hydrolase 10303
Beta-carbonic anhydrase 10303
Carbonic anhydrase 20202
Glutamate receptor ionotropic, NMDA 2B05210
Squalene synthase0101
Neuronal acetylcholine receptor subunit alpha-70101
Carbonic anhydrase 9012119
Carbonic anhydrase0303
Carbonic anhydrase, alpha family 0202
Carbonic anhydrase 0305
Carbonic anhydrase 30303
Carbonic anhydrase0306
Carbonic anhydrase0306
Carbonic anhydrase 0202
Sigma intracellular receptor 20303
Delta carbonic anhydrase0202
Sigma non-opioid intracellular receptor 10314
Renin0101
Carbonic anhydrase 0204
Endochitinase A10101
Multidrug resistance-associated protein 10101
Carbonic anhydrase 130517
GABA theta subunit177226
Canalicular multispecific organic anion transporter 1037038
Carbonic anhydrase 40404
Carbonic anhydrase 150508
Acidic mammalian chitinase0101
Carbonic anhydrase 1306010
Carbonic anhydrase 70101
Gamma-aminobutyric acid receptor subunit epsilon177226
Carbonic anhydrase 0101
Carbonic anhydrase 1407113
Carbonic anhydrase 0101
Carbonic anhydrase 2, isoform A 0101
Carbonic anhydrase 5B, mitochondrial08114
Chain A, Heat Shock Protein 900011
Chain A, GLUTAMINE PHOSPHORIBOSYLPYROPHOSPHATE AMIDOTRANSFERASE0011
Chain B, GLUTAMINE PHOSPHORIBOSYLPYROPHOSPHATE AMIDOTRANSFERASE0011
Chain A, EOSINOPHIL-DERIVED NEUROTOXIN0101
Chain A, EOSINOPHIL-DERIVED NEUROTOXIN0101
Chain A, EOSINOPHIL-DERIVED NEUROTOXIN0101
Chain A, Myosin Ie Heavy Chain0011
Chain A, Preprotein translocase secA0011
Chain A, Ribonuclease pancreatic0101
Chain A, Ribonuclease pancreatic0101
Chain A, Ribonuclease pancreatic0101
Chain A, Ribonuclease pancreatic0101
Chain A, Ribonuclease pancreatic0101
Chain A, Phosphoribosylformylglycinamidine synthase0101
Chain A, nucleoside diphosphate kinase A0011
Chain B, nucleoside diphosphate kinase A0011
Chain D, DNA polymerase III subunit gamma0011
Chain D, DNA polymerase III subunit gamma0011
Chain A [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 30011
Chain A [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 30011
Chain A, Kinesin-like protein KIF110101
regulator of G-protein signaling 4130013
HPr kinase/phosphorylase0011
Mitogen-activated protein kinase kinase kinase 70011
ATP-dependent molecular chaperone HSP820001
Heat shock protein HSP 90-alpha0113
Heat shock protein HSP 90-beta0113
2-dehydropantoate 2-reductase0112
Heat shock 70 kDa protein 1A 0112
Endoplasmic reticulum chaperone BiP0011
Heat shock cognate 71 kDa protein0011
Pyruvate kinase PKM 0001
Pyruvate kinase PKLR 0001
Endoplasmin0001
Heat shock cognate 71 kDa protein0011
5'-nucleotidase0101
Mu-type opioid receptor08311
Delta-type opioid receptor0628
Kappa-type opioid receptor08210
Endoplasmin0112
P2Y purinoceptor 20011
Phosphatidylinositol 4-kinase alpha0202
P2X purinoceptor 10022
P2Y purinoceptor 10011
P2Y purinoceptor 10011
P2X purinoceptor 10112
P2X purinoceptor 40022
P2X purinoceptor 50011
P2X purinoceptor 60011
P2X purinoceptor 30011
Inositol monophosphatase 17007
Heat shock protein 75 kDa, mitochondrial0101
P2Y purinoceptor 60011
Phosphatidylinositol 4-kinase type 2-beta0202
P2Y purinoceptor 110011
Phosphatidylinositol 4-kinase type 2-alpha0202
P2Y purinoceptor 120213
Sensor protein kinase WalK0101
Phosphatidylinositol 4-kinase beta0202
P2X purinoceptor 20022
glp-1 receptor, partial110011
ATAD5 protein, partial180018
Fumarate hydratase110011
TDP1 protein470047
caspase 7, apoptosis-related cysteine protease130013
progesterone receptor340034
farnesoid X nuclear receptor310031
pregnane X nuclear receptor420042
polyprotein110011
67.9K protein170017
vitamin D (1,25- dihydroxyvitamin D3) receptor360036
caspase-3130013
IDH1240024
aryl hydrocarbon receptor210021
nuclear receptor subfamily 1, group I, member 2120012
cellular tumor antigen p53 isoform a100010
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1110011
nuclear factor erythroid 2-related factor 2 isoform 2200021
transcriptional regulator ERG isoform 36006
thyroid hormone receptor beta isoform 2420042
histone deacetylase 9 isoform 32002
mitogen-activated protein kinase 19009
urokinase-type plasminogen activator precursor110011
plasminogen precursor110011
urokinase plasminogen activator surface receptor precursor110011
Vif0001
DNA dC->dU-editing enzyme APOBEC-3G isoform 12002
neuropeptide S receptor isoform A5005
Cellular tumor antigen p53410041
Integrin beta-382010
Integrin alpha-IIb82010
Methionine aminopeptidase0101
ATPase family AAA domain-containing protein 5240024
Ataxin-2280028
Sex hormone-binding globulin0055
Corticosteroid-binding globulin0404
Mineralocorticoid receptor 0539
Mineralocorticoid receptor0101
Solute carrier organic anion transporter family member 1A10102
Chain A, PLASMINOGEN0022
Chain A, PLASMINOGEN0022
Chain A, ATP-DEPENDENT DNA HELICASE Q19009
Chain A, Ferritin light chain130013
Chain A, Apolipoprotein0011
15-lipoxygenase, partial100010
EWS/FLI fusion protein270027
nonstructural protein 17007
D(1A) dopamine receptor100010
peptidyl-prolyl cis-trans isomerase NIMA-interacting 15005
histone acetyltransferase KAT2A isoform 1140014
Rap guanine nucleotide exchange factor 35005
Plasminogen0628
Proton-coupled amino acid transporter 10505
Chain A, HADH2 protein140014
Chain B, HADH2 protein140014
USP1 protein, partial230023
NFKB1 protein, partial6006
GLS protein170017
cytochrome P450 2D6200020
cytochrome P450 2D6 isoform 16006
atrial natriuretic peptide receptor 2 precursor1001
serine/threonine-protein kinase mTOR isoform 17007
muscarinic acetylcholine receptor M1140014
Solute carrier family 22 member 1 09010
Polyunsaturated fatty acid lipoxygenase ALOX15B100010
Voltage-dependent L-type calcium channel subunit alpha-1F0505
5-hydroxytryptamine receptor 4012012
Albumin0033
High affinity nerve growth factor receptor0123
Aldo-keto reductase family 1 member B1013013
Muscarinic acetylcholine receptor M2010215
Muscarinic acetylcholine receptor M409112
Muscarinic acetylcholine receptor M10316
Muscarinic acetylcholine receptor M30316
Muscarinic acetylcholine receptor M40316
Muscarinic acetylcholine receptor M50316
Muscarinic acetylcholine receptor M508111
Alpha-2A adrenergic receptor012216
Muscarinic acetylcholine receptor M20317
Muscarinic acetylcholine receptor M1010215
Angiotensin-converting enzyme0606
D(2) dopamine receptor0729
Alpha-2B adrenergic receptor012115
Alpha-2C adrenergic receptor09213
5-hydroxytryptamine receptor 1A010112
Muscarinic acetylcholine receptor M3010214
D(1A) dopamine receptor0819
D(1B) dopamine receptor0101
UDP-glucuronosyltransferase 1A40002
Sodium-dependent noradrenaline transporter 012113
Histamine H2 receptor0404
Alpha-1D adrenergic receptor08314
5-hydroxytryptamine receptor 2A0819
5-hydroxytryptamine receptor 2C012113
5-hydroxytryptamine receptor 1B0707
5-hydroxytryptamine receptor 1D0202
5-hydroxytryptamine receptor 1F0202
5-hydroxytryptamine receptor 60101
Histamine H1 receptor0101
Sodium-dependent serotonin transporter012113
5-hydroxytryptamine receptor 7 0202
5-hydroxytryptamine receptor 5A0101
5-hydroxytryptamine receptor 5B0101
Histamine H1 receptor0202
D(3) dopamine receptor0808
Sodium channel protein type 1 subunit alpha0606
Sodium channel protein type 4 subunit alpha08010
UDP-glucuronosyltransferase 1A30001
5-hydroxytryptamine receptor 3A0101
5-hydroxytryptamine receptor 2B016117
Alpha-1A adrenergic receptor017219
Histamine H2 receptor121116
5-hydroxytryptamine receptor 609110
5-hydroxytryptamine receptor 70606
Voltage-dependent N-type calcium channel subunit alpha-1B0101
Sodium channel protein type 7 subunit alpha0404
Voltage-dependent L-type calcium channel subunit alpha-1D 0505
Sodium-dependent dopamine transporter 010010
Potassium voltage-gated channel subfamily H member 2020020
Voltage-dependent L-type calcium channel subunit alpha-1S0505
Voltage-dependent L-type calcium channel subunit alpha-1C0606
Sodium channel protein type 5 subunit alpha0707
Sodium channel protein type 9 subunit alpha0909
5-hydroxytryptamine receptor 4 0101
Nuclear receptor subfamily 3 group C member 3 0606
Sodium channel protein type 2 subunit alpha0606
Sigma non-opioid intracellular receptor 1011112
5-hydroxytryptamine receptor 3B0101
Sodium channel protein type 3 subunit alpha0707
Sodium channel protein type 11 subunit alpha0404
Sodium channel protein type 8 subunit alpha0404
Histamine H3 receptor0101
Sodium channel protein type 10 subunit alpha0404
Chain A, Cruzipain100010
interleukin 8110011
phosphopantetheinyl transferase190019
tumor necrosis factor2002
vitamin D3 receptor isoform VDRA200020
Nuclear receptor ROR-gamma122216
Aurora kinase B0101
Broad substrate specificity ATP-binding cassette transporter ABCG20507
Chain A, ADIPOCYTE LIPID-BINDING PROTEIN0011
Chain A, SERUM ALBUMIN0011
Chain A, SERUM ALBUMIN0011
Chain A, 2-oxoglutarate Oxygenase200020
Microtubule-associated protein tau220022
thioredoxin glutathione reductase100010
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)5005
ubiquitin carboxyl-terminal hydrolase 2 isoform a8008
nuclear receptor ROR-gamma isoform 1170017
lethal(3)malignant brain tumor-like protein 1 isoform I2002
DNA polymerase kappa isoform 1150015
cytochrome P450 3A4 isoform 1170017
caspase-1 isoform alpha precursor5005
Fatty-acid amide hydrolase 10202
Prostaglandin G/H synthase 1 0305
Trypsin0101
Coagulation factor VII0101
60 kDa chaperonin0202
60 kDa heat shock protein, mitochondrial0303
Aromatase0202
Tissue factor0202
Fatty acid-binding protein, adipocyte0112
Prostaglandin G/H synthase 209314
Nuclear receptor subfamily 4 group A member 20011
10 kDa heat shock protein, mitochondrial0303
Calmodulin 0001
Disintegrin and metalloproteinase domain-containing protein 175005
Prostaglandin G/H synthase 20506
Solute carrier organic anion transporter family member 2A10103
Fatty acid-binding protein 50101
Fatty acid-binding protein 50011
Thiosulfate sulfurtransferase0303
Lanosterol 14-alpha demethylase0101
60 kDa chaperonin 0303
10 kDa chaperonin 0303
Solute carrier organic anion transporter family member 1B3011014
Cytosolic phospholipase A2 gamma0202
Transient receptor potential cation channel subfamily V member 20101
Solute carrier organic anion transporter family member 1B108010
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN0011
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN0011
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN0011
thyroid stimulating hormone receptor200020
alpha-galactosidase6006
cytochrome P450 2C19 precursor5005
flap endonuclease 1120012
DNA polymerase iota isoform a (long)200020
lethal factor (plasmid)130013
Nitric oxide synthase, endothelial0002
Nitric oxide synthase, brain0001
Nitric oxide synthase, brain 0001
Nitric oxide synthase, inducible0102
Nitric oxide synthase, inducible0013
Cationic amino acid transporter 30101
ATP-dependent phosphofructokinase170017
Chain A, Phospholipase A2 isoform 30011
GTP-binding protein (rab7)0022
ras protein, partial0022
hypothetical protein, conserved2002
glucocerebrosidase5005
Rac1 protein0022
cell division cycle 42 (GTP binding protein, 25kDa), partial0022
Prostaglandin-H2 D-isomerase0202
Prostaglandin G/H synthase 2 0304
Epidermal growth factor receptor0707
Fatty acid-binding protein, liver0303
Myeloperoxidase0202
Prostaglandin G/H synthase 10506
Seed linoleate 13S-lipoxygenase-10202
Glutathione hydrolase 1 proenzyme0101
Prostaglandin G/H synthase 10809
Substance-P receptor0303
Urotensin-2 receptor0202
4-aminobutyrate aminotransferase, mitochondrial0101
Ras-related protein Rab-2A0022
Rho-associated protein kinase 20202
Nicotinate phosphoribosyltransferase0303
Solute carrier family 22 member 200404
Solute carrier family 22 member 60404
Sigma non-opioid intracellular receptor 10011
SMAD family member 2170017
SMAD family member 3170017
estrogen receptor 2 (ER beta)230023
Caspase-77007
caspase-37007
Solute carrier organic anion transporter family member 2B1 0203
3-hydroxy-3-methylglutaryl-coenzyme A reductase0202
ATP-dependent translocase ABCB1015121
Insulin receptor 0101
Dipeptidyl peptidase 40101
3-hydroxy-3-methylglutaryl-coenzyme A reductase 0101
Histone deacetylase 10505
Histone deacetylase 20505
Histone deacetylase 60505
cystic fibrosis transmembrane conductance regulator0101
DNA polymerase beta2002
short transient receptor potential channel 6 isoform 10011
Muscarinic acetylcholine receptor M10001
Muscarinic acetylcholine receptor M40101
Reverse transcriptase/RNaseH 0102
Muscarinic acetylcholine receptor0112
acetylcholinesterase140014
P531001
peripheral myelin protein 22 isoform 1110011
hemoglobin subunit beta2002
M-phase phosphoprotein 8100010
Bile salt export pump0909
Protein-arginine deiminase type-40303
pregnane X receptor110011
galanin receptor type 30101
Glucocorticoid receptor017325
Glycine receptor subunit alpha-1016016
Glycine receptor subunit beta016016
Glycine receptor subunit alpha-2016016
Glycine receptor subunit alpha-3016016
ORF730011
Chain A, Putative fructose-1,6-bisphosphate aldolase100010
Caspase-75005
PPM1D protein100010
Angiotensin-converting enzyme 0102
B2 bradykinin receptor0101
B2 bradykinin receptor0417
B1 bradykinin receptor0101
Olfactory receptor 51E20033
Chain A, JmjC domain-containing histone demethylation protein 3A7007
apical membrane antigen 1, AMA15005
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a180018
Matrix metalloproteinase-90303
Vpr6006
Major prion protein0011
Sodium channel protein type 1 subunit alpha0404
Sodium channel protein type 2 subunit alpha0606
Sodium channel protein type 3 subunit alpha0404
UDP-glucuronosyltransferase 2B70105
Cytochrome P450 2J20707
Frizzled-80011
P2X purinoceptor 40101
Vasopressin V2 receptor0123
Oxytocin receptor0336
Vasopressin V1a receptor0437
Vasopressin V1b receptor0123
Oxytocin receptor0022
Chain A, serum paraoxonase0101
Neutrophil cytosol factor 10101
Poly [ADP-ribose] polymerase tankyrase-20101
Chain A, Carbonic anhydrase II0101
Smad36006
thyrotropin-releasing hormone receptor6006
interferon gamma precursor0003
prostaglandin E2 receptor EP2 subtype1002
potassium voltage-gated channel subfamily H member 2 isoform d100010
Prostaglandin E synthase0202
Histone deacetylase 30404
3-phosphoinositide-dependent protein kinase 10101
cGMP-specific 3',5'-cyclic phosphodiesterase0202
Cytochrome c oxidase subunit 10101
Cytochrome c oxidase subunit 20101
Catechol O-methyltransferase0101
Cytochrome c oxidase subunit 20202
Procathepsin L0213
Neuronal acetylcholine receptor subunit alpha-43306
Quinolone resistance protein NorA0101
Adenosine receptor A3011112
Neuronal acetylcholine receptor subunit beta-23306
Beta-3 adrenergic receptor09312
Alpha-1B adrenergic receptor016218
Calpain-2 catalytic subunit0101
Prostaglandin G/H synthase 10202
Cruzipain0101
Sodium/hydrogen exchanger 10101
Indoleamine 2,3-dioxygenase 10303
Bifunctional epoxide hydrolase 20202
Prostaglandin G/H synthase 2 0202
Histone deacetylase 40404
Prostaglandin G/H synthase 20304
Mitogen-activated protein kinase 140101
Prostaglandin G/H synthase 1 0202
Prostaglandin G/H synthase 10101
Cyclooxygenase-2 0101
Histone deacetylase 70404
Rap guanine nucleotide exchange factor 42002
Polyamine deacetylase HDAC100404
Histone deacetylase 11 0404
Histone deacetylase 80404
Histone deacetylase 90404
Histone deacetylase 50404
Thrombopoietin4004
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)150015
bromodomain adjacent to zinc finger domain 2B120012
FAD-linked sulfhydryl oxidase ALR0001
Spike glycoprotein240125
streptokinase A precursor0022
Dihydroxyacetone phosphate acyltransferase0001
30S ribosomal protein S60101
30S ribosomal protein S70101
50S ribosomal protein L150101
50S ribosomal protein L100101
50S ribosomal protein L110101
50S ribosomal protein L7/L120101
50S ribosomal protein L190101
50S ribosomal protein L10101
50S ribosomal protein L200101
50S ribosomal protein L270101
50S ribosomal protein L280101
50S ribosomal protein L290101
50S ribosomal protein L310101
50S ribosomal protein L31 type B0101
50S ribosomal protein L320101
50S ribosomal protein L330101
50S ribosomal protein L340101
50S ribosomal protein L350101
50S ribosomal protein L360101
30S ribosomal protein S100101
30S ribosomal protein S110101
30S ribosomal protein S120101
30S ribosomal protein S130101
30S ribosomal protein S160101
30S ribosomal protein S180101
30S ribosomal protein S190101
30S ribosomal protein S200101
30S ribosomal protein S20101
30S ribosomal protein S30101
30S ribosomal protein S40101
30S ribosomal protein S50101
30S ribosomal protein S80101
30S ribosomal protein S90101
50S ribosomal protein L130101
50S ribosomal protein L140101
50S ribosomal protein L160101
50S ribosomal protein L230101
30S ribosomal protein S150101
50S ribosomal protein L170101
50S ribosomal protein L210101
50S ribosomal protein L300101
50S ribosomal protein L60101
30S ribosomal protein S140101
30S ribosomal protein S170101
30S ribosomal protein S10101
50S ribosomal protein L180101
50S ribosomal protein L20101
50S ribosomal protein L30101
50S ribosomal protein L240101
50S ribosomal protein L40101
50S ribosomal protein L220101
50S ribosomal protein L50101
30S ribosomal protein S210101
50S ribosomal protein L250101
50S ribosomal protein L36 20101
Methionine--tRNA ligase, mitochondrial0011
Gamma-aminobutyric acid receptor subunit pi0505
Gamma-aminobutyric acid receptor subunit delta0505
Gamma-aminobutyric acid receptor subunit alpha-10102
Gamma-aminobutyric acid receptor subunit beta-10102
Gamma-aminobutyric acid receptor subunit alpha-20102
Gamma-aminobutyric acid receptor subunit alpha-30102
Gamma-aminobutyric acid receptor subunit alpha-10639
Gamma-aminobutyric acid receptor subunit beta-10527
Gamma-aminobutyric acid receptor subunit gamma-20639
Gamma-aminobutyric acid receptor subunit alpha-40102
Gamma-aminobutyric acid receptor subunit gamma-20102
Gamma-aminobutyric acid receptor subunit beta-30628
Translocator protein0101
Translocator protein0101
Cholecystokinin receptor type A0101
Gastrin/cholecystokinin type B receptor0101
Gamma-aminobutyric acid receptor subunit alpha-50527
Gamma-aminobutyric acid receptor subunit alpha-30527
Gamma-aminobutyric acid receptor subunit alpha-20527
Gamma-aminobutyric acid receptor subunit beta-20538
Gamma-aminobutyric acid receptor subunit alpha-40527
Gamma-aminobutyric acid receptor subunit epsilon0505
Gamma-aminobutyric acid receptor subunit alpha-60527
Gamma-aminobutyric acid receptor subunit gamma-10505
Gamma-aminobutyric acid receptor subunit gamma-30505
Gamma-aminobutyric acid receptor subunit theta0505
Cytochrome P450 2D10202
Cytochrome P450 2D260202
Cytochrome P450 2D30202
Kappa-type opioid receptor0101
Mu-type opioid receptor0101
Cytochrome P450 2D40202
Mas-related G-protein coupled receptor member X20011
endonuclease IV6006
dopamine D1 receptor3003
atrial natriuretic peptide receptor 1 precursor5005
Potassium voltage-gated channel subfamily A member 10112
TAR DNA-binding protein 43100010
Multidrug and toxin extrusion protein 1010010
RAD510101
huntingtin isoform 25005
histone-lysine N-methyltransferase 2A isoform 2 precursor6006
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 10101
Growth factor receptor-bound protein 20101
Pantothenate synthetase0101
Discoidin domain-containing receptor 20101
Growth factor receptor-bound protein 2 0101
Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase0011
Solute carrier family 22 member 30202
Solute carrier family 22 member 20303
Hsf1 protein0022
PAX80002
STAT3, partial0101
NPC intracellular cholesterol transporter 1 precursor4004
ras-related protein Rab-9A6006
signal transducer and activator of transcription 1-alpha/beta isoform alpha0101
Solute carrier organic anion transporter family member 1A40203
Sodium/potassium-transporting ATPase subunit alpha-1 0202
Sodium/potassium-transporting ATPase subunit beta-10202
Sodium/potassium-transporting ATPase subunit alpha-20101
Sodium/potassium-transporting ATPase subunit alpha-3 0101
ATP-dependent translocase ABCB10303
Sodium/potassium-transporting ATPase subunit beta-1 0101
Replicase polyprotein 1ab0213
Sodium/potassium-transporting ATPase subunit alpha-30101
Sodium/potassium-transporting ATPase subunit beta-20101
ATP-dependent translocase ABCB10303
Sodium/potassium-transporting ATPase subunit alpha-20202
Sodium/potassium-transporting ATPase subunit alpha-10101
Sodium/potassium-transporting ATPase subunit beta-30101
Sodium/potassium-transporting ATPase subunit gamma0101
Sodium/potassium-transporting ATPase subunit alpha-40101
Sodium/potassium-transporting ATPase subunit alpha-40101
Solute carrier organic anion transporter family member 4C10001
Solute carrier organic anion transporter family member 4C10001
Solute carrier organic anion transporter family member 1A40001
polyunsaturated fatty acid lipoxygenase ALOX122002
runt-related transcription factor 1 isoform AML1b1001
core-binding factor subunit beta isoform 21001
Glutamate receptor 11001
Glutamate receptor 31001
Glutamate receptor 41001
Voltage-dependent L-type calcium channel subunit alpha-1C0303
Voltage-dependent L-type calcium channel subunit alpha-1C0303
Voltage-dependent L-type calcium channel subunit alpha-1D0202
Voltage-dependent L-type calcium channel subunit alpha-1S0202
Cereblon isoform 40202
Insulin-like growth factor-binding protein 50011
Choline O-acetyltransferase 0101
Protein cereblon0202
Solute carrier family 22 member 20608
Solute carrier organic anion transporter family member 1A50001
Prostaglandin E2 receptor EP3 subtype0202
Prostaglandin E2 receptor EP4 subtype0202
Prostaglandin E2 receptor EP1 subtype0213
Prostaglandin E2 receptor EP1 subtype0202
Prostaglandin E2 receptor EP4 subtype0213
Prostaglandin F2-alpha receptor0011
Prostaglandin E2 receptor EP4 subtype0112
Prostaglandin E2 receptor EP3 subtype0213
Prostaglandin E2 receptor EP2 subtype0213
Prostacyclin receptor0213
Solute carrier family 22 member 60204
Solute carrier family 22 member 70003
Prostaglandin E2 receptor EP2 subtype0202
Prostaglandin E2 receptor EP2 subtype0112
Solute carrier family 22 member 80204
Solute carrier family 22 member 70001
Solute carrier organic anion transporter family member 2A10001
Solute carrier family 22 member 110002
Solute carrier organic anion transporter family member 1B20001
Solute carrier family 22 member 70001
Chain A, Breast cancer type 1 susceptibility protein1001
acid sphingomyelinase3003
RGS121001
90-kda heat shock protein beta HSP90 beta, partial0101
DNA polymerase III, partial3003
isocitrate dehydrogenase 1, partial1001
LANA0001
NPYLR7B0022
serine-protein kinase ATM isoform a1001
lysosomal alpha-glucosidase preproprotein4004
cytochrome P450 2C9 precursor4004
guanine nucleotide-binding protein G(i) subunit alpha-1 isoform 11001
importin subunit beta-1 isoform 15005
serine/threonine-protein kinase PLK11001
eyes absent homolog 2 isoform a2002
heat shock protein HSP 90-alpha isoform 20102
snurportin-15005
tumor susceptibility gene 101 protein1001
GTP-binding nuclear protein Ran isoform 12002
DNA dC->dU-editing enzyme APOBEC-3F isoform a1001
kelch-like ECH-associated protein 10002
cGMP-dependent 3',5'-cyclic phosphodiesterase0101
Multidrug resistance-associated protein 50101
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta0101
High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A0101
3',5'-cyclic-AMP phosphodiesterase 0202
Polyunsaturated fatty acid lipoxygenase ALOX150606
Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha0101
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma0101
cAMP-specific 3',5'-cyclic phosphodiesterase 4A0101
Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta0101
Cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha'0101
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A0101
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B0101
cAMP-specific 3',5'-cyclic phosphodiesterase 4B0101
cAMP-specific 3',5'-cyclic phosphodiesterase 4C0101
cAMP-specific 3',5'-cyclic phosphodiesterase 4D0101
cGMP-inhibited 3',5'-cyclic phosphodiesterase B0202
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A0101
Retinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma0101
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C0101
cGMP-inhibited 3',5'-cyclic phosphodiesterase A0202
Exopolyphosphatase PRUNE10101
Multidrug and toxin extrusion protein 20505
Equilibrative nucleoside transporter 10202
Single-stranded DNA cytosine deaminase1001
Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A0101
cAMP-specific 3',5'-cyclic phosphodiesterase 7B0101
Phosphodiesterase 0101
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A0101
Eyes absent homolog 20101
Amyloid-beta precursor protein1203
Metallo-beta-lactamase VIM-130101
Beta-lactamase 0101
Beta-lactamase 0101
Beta-lactamase VIM-1 0101
chaperonin-containing TCP-1 beta subunit homolog4004
ubiquitin-conjugating enzyme E2 N0303
protein AF-9 isoform a0001
Estrogen receptor010314
Receptor tyrosine-protein kinase erbB-20202
Tyrosine-protein kinase Fyn0404
Substance-K receptor0404
C-8 sterol isomerase0202
Alpha-synuclein2103
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase0314
Genome polyprotein 0101
Genome polyprotein 0112
relaxin receptor 1 isoform 11001
Flavin reductase (NADPH)0011
large T antigen0101
Glutaminyl-peptide cyclotransferase0101
Cytochrome P450 2B10101
UDP-glucuronosyltransferase 1A1 0103
3-oxo-5-alpha-steroid 4-dehydrogenase 1 0101
Adenosine receptor A2a0516
Sulfotransferase 1A10214
Aldehyde oxidase0202
Nuclear receptor subfamily 1 group I member 3 0101
Estrogen receptor beta0639
Type IV secretion-like conjugative transfer relaxase protein TraI 0101
LMP1 [Human herpesvirus 4]0001
nuclear receptor coactivator 1 isoform 1 [Homo sapiens]0202
transactivating tegument protein VP16 [Human herpesvirus 1]0202
nuclear receptor coactivator 3 isoform a0202
Prothrombin0102
Regulatory protein E20022
DNA topoisomerase 10102
DNA topoisomerase 2-alpha0117
DNA topoisomerase 20001
Glutamate receptor ionotropic, NMDA 1 0429
Caspase-30101
Glutamate receptor ionotropic, NMDA 2A 0429
Glutamate receptor ionotropic, NMDA 2C0429
DNA topoisomerase 2-alpha 0001
DNA topoisomerase 2-beta0118
Glutamate receptor ionotropic, NMDA 2D0429
Tubulin beta-2B chain0202
Integrase 0101
Similar to alpha-tubulin isoform 1 0202
Similar to alpha-tubulin isoform 1 0202
Glutamate receptor ionotropic, NMDA 3B0429
Glutamate receptor ionotropic, NMDA 3A0429
Chain A, Uracil Phosphoribosyltransferase0101
Skn7p0001
Solute carrier family 22 member 80001
Thymidylate synthase0303
HSP40, subfamily A [Plasmodium falciparum 3D7]0001
Albumin0358
Glucose-6-phosphate 1-dehydrogenase0202
Corticosteroid 11-beta-dehydrogenase isozyme 10101
Adenosine receptor A10101
6-phosphogluconate dehydrogenase, decarboxylating0202
Holo-[acyl-carrier-protein] synthase0101
Sodium/bile acid cotransporter0202
G-protein coupled receptor 350112
CDGSH iron-sulfur domain-containing protein 10202
Voltage-dependent calcium channel subunit alpha-2/delta-10101
Gamma-aminobutyric acid 0112
Gamma-aminobutyric acid receptor subunit rho-30011
Gamma-aminobutyric acid type B receptor subunit 20011
Gamma-aminobutyric acid type B receptor subunit 20101
Gamma-aminobutyric acid receptor subunit alpha-60112
Gamma-aminobutyric acid receptor subunit gamma-20112
Gamma-aminobutyric acid receptor subunit delta0112
Sodium- and chloride-dependent GABA transporter 10303
Gamma-aminobutyric acid receptor subunit rho-10022
Gamma-aminobutyric acid receptor subunit alpha-20112
Gamma-aminobutyric acid receptor subunit alpha-30112
Gamma-aminobutyric acid receptor subunit gamma-30112
Gamma-aminobutyric acid receptor subunit rho-20011
Sodium- and chloride-dependent GABA transporter 10101
Sodium- and chloride-dependent taurine transporter0101
Sodium- and chloride-dependent GABA transporter 20303
Sodium- and chloride-dependent GABA transporter 30303
Sodium- and chloride-dependent GABA transporter 10101
Sodium- and chloride-dependent GABA transporter 20202
Sodium- and chloride-dependent GABA transporter 30202
Sodium- and chloride-dependent betaine transporter0303
Sodium- and chloride-dependent betaine transporter0101
Sodium- and chloride-dependent GABA transporter 30101
Gamma-aminobutyric acid receptor subunit beta-10112
Gamma-aminobutyric acid receptor subunit alpha-10112
Gamma-aminobutyric acid receptor subunit beta-30112
4-aminobutyrate aminotransferase, mitochondrial0001
4-aminobutyrate aminotransferase, mitochondrial0001
Sterol O-acyltransferase 10011
Gamma-aminobutyric acid receptor subunit alpha-50112
Gamma-aminobutyric acid receptor subunit pi0112
Gamma-aminobutyric acid receptor subunit alpha-40112
Platelet glycoprotein VI0011
Gamma-aminobutyric acid receptor subunit theta0112
Sodium- and chloride-dependent GABA transporter 20101
Gamma-aminobutyric acid receptor subunit gamma-10112
Gamma-aminobutyric acid type B receptor subunit 10011
Gamma-aminobutyric acid type B receptor subunit 10101
Chain B, EUKARYOTIC TRANSLATION INITIATION FACTOR 4E0011
Glycine receptor subunit alpha-10022
Sodium- and chloride-dependent glycine transporter 10101
Large neutral amino acids transporter small subunit 10505
Serine racemase0101
Sodium- and chloride-dependent glycine transporter 20101
Stromelysin-10123
Urease subunit alpha0202
Ribonucleoside-diphosphate reductase large subunit0101
Urease subunit beta0202
Thymidine kinase 0101
Thymidine kinase, cytosolic0101
Thymidine phosphorylase0001
Thymidine kinase0001
Chain A, membrane-associated prostaglandin E synthase-20101
Parkin2002
Phospholipase A2, major isoenzyme0101
Interleukin-80101
Androgen receptor0426
Polyunsaturated fatty acid 5-lipoxygenase0102
Aldo-keto reductase family 1 member B10202
Aldo-keto reductase family 1 member B10202
Aldo-keto reductase family 1 member C40202
Sodium-dependent dopamine transporter0202
Thromboxane-A synthase 0202
Caspase-10001
Multidrug resistance-associated protein 1 0102
Peroxisome proliferator-activated receptor gamma0011
Aldo-keto reductase family 1 member C30303
C-X-C chemokine receptor type 30101
Aldo-keto reductase family 1 member C2 0202
Prostaglandin D2 receptor 0202
Solute carrier organic anion transporter family member 1A30102
Lactoylglutathione lyase0101
Aldo-keto reductase family 1 member C10202
Uracil nucleotide/cysteinyl leukotriene receptor0202
Dehydrogenase/reductase SDR family member 90101
Prostaglandin D2 receptor 20112
Beta-1 adrenergic receptor 0125
beta-2 adrenergic receptor2002
hexokinase-4 isoform 12002
glucokinase regulatory protein2002
Beta-2 adrenergic receptor0449
Beta-1 adrenergic receptor0639
Beta-2 adrenergic receptor0416
Beta-1 adrenergic receptor0428
Beta-2 adrenergic receptor0011
Alpha-2B adrenergic receptor0426
D(4) dopamine receptor0404
Alpha-2C adrenergic receptor0426
Alpha-2A adrenergic receptor0426
Alpha-1D adrenergic receptor0729
Beta-adrenergic receptor kinase 10011
Beta-3 adrenergic receptor0011
Beta-3 adrenergic receptor0314
Vasopressin V1a receptor0112
Beta-1 adrenergic receptor0213
Alpha-1A adrenergic receptor03412
Alpha-1B adrenergic receptor0238
Beta-2 adrenergic receptor0202
Taste receptor type 2 member 380011
Taste receptor type 2 member 390011
Taste receptor type 2 member 400011
Taste receptor type 2 member 410011
Taste receptor type 2 member 430011
Taste receptor type 2 member 310011
Taste receptor type 2 member 450011
Taste receptor type 2 member 460011
Taste receptor type 2 member 300011
Taste receptor type 2 member 190011
Taste receptor type 2 member 200011
Taste receptor type 2 member 500011
Taste receptor type 2 member 600011
Oxytocin receptor0112
Beta-2 adrenergic receptor 0112
Taste receptor type 2 member 420011
Beta-2 adrenergic receptor0135
Taste receptor type 2 member 160011
Taste receptor type 2 member 140011
Taste receptor type 2 member 130011
Taste receptor type 2 member 100011
Taste receptor type 2 member 90011
Taste receptor type 2 member 80011
Taste receptor type 2 member 70011
Taste receptor type 2 member 50011
Taste receptor type 2 member 40011
Taste receptor type 2 member 30011
Taste receptor type 2 member 10011
2,3-bisphosphoglycerate-independent phosphoglycerate mutase1001
Chymotrypsinogen A0101
Glutamate receptor ionotropic, NMDA 2D0101
Acetylcholinesterase0202
Glutamate receptor ionotropic, NMDA 3B0101
Glutamate receptor ionotropic, NMDA 10202
Glutamate receptor ionotropic, NMDA 2A0202
Glutamate receptor ionotropic, NMDA 2B0202
Glutamate receptor ionotropic, NMDA 2C0101
Glutamate receptor ionotropic, NMDA 3A0101
Synaptic vesicle glycoprotein 2A0101
WRN1001
integrase, partial0101
lens epithelium-derived growth factor p750101
pyruvate kinase1001
DNA polymerase eta isoform 12002
Polyphenol oxidase 20104
Plasma kallikrein0002
Tyrosine-protein kinase Lck0202
Tyrosinase0101
Solute carrier family 15 member 10101
SLC16A10 protein0002
Carbonic anhydrase-like protein, putative0002
Monocarboxylate transporter 100002
phosphoglycerate kinase1001
Potassium channel subfamily K member 30303
Potassium channel subfamily K member 20415
Potassium voltage-gated channel subfamily A member 50101
Potassium voltage-gated channel subfamily D member 20101
Potassium channel subfamily K member 180101
Type-1A angiotensin II receptor 0101
Type-1B angiotensin II receptor0202
Type-2 angiotensin II receptor0101
5-hydroxytryptamine receptor 1A0101
Type-1 angiotensin II receptor0101
Amine oxidase [flavin-containing] B0101
Amine oxidase [flavin-containing] B0101
Synaptic vesicular amine transporter0101
Trace amine-associated receptor 10011
Trace amine-associated receptor 10011
Trace amine-associated receptor 10011
Trace amine-associated receptor 10011
Chain A, Methionyl-tRNA synthetase0011
Chain A, Methionyl-tRNA synthetase0011
Chain A, Aminopeptidase0101
Chain A, Methionine aminopeptidase0101
S-ribosylhomocysteine lyase0101
Adenylate cyclase type 50001
S-adenosylmethionine synthase isoform type-10001
S-adenosylmethionine synthase isoform type-20001
Fatty acid synthase0101
Chain B, DIHYDROFOLATE REDUCTASE0011
Chain B, DIHYDROFOLATE REDUCTASE0011
Chain B, DIHYDROFOLATE REDUCTASE0011
ClpP1001
Thymidylate synthase 0101
Thymidylate synthase 0101
Toll-like receptor 40101
Fatty-acid amide hydrolase 10101
ATP-binding cassette sub-family C member 30102
Dihydrofolate reductase0405
Dihydrofolate reductase0203
Dihydrofolate reductase 0202
Dihydrofolate reductase0101
Dihydrofolate reductase0101
Dihydrofolate reductase0203
Thymidylate synthase0101
Tyrosine-protein kinase ABL10011
Thymidylate synthase0202
Bifunctional dihydrofolate reductase-thymidylate synthase0101
High mobility group protein B10022
Dihydrofolate reductase0101
Thymidylate synthase0101
Dihydrofolate reductase0224
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Folate receptor beta0101
Cytochrome P450 11B1, mitochondrial 0101
Folate receptor alpha0101
Dihydrofolate reductase0202
Histidine decarboxylase0101
Trifunctional purine biosynthetic protein adenosine-30101
Cyclin-dependent kinase 20011
Bifunctional purine biosynthesis protein ATIC0202
Kappa-type opioid receptor0101
Reduced folate transporter0202
Folylpolyglutamate synthase, mitochondrial0103
Dihydrofolate reductase0101
Pteridine reductase 10101
Folylpolyglutamate synthase, mitochondrial0103
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Canalicular multispecific organic anion transporter 10102
Trifunctional purine biosynthetic protein adenosine-30101
Dihydrofolate reductase 0101
Dihydrofolate reductase0101
ATP-binding cassette sub-family C member 110001
Proton-coupled folate transporter0101
Multidrug resistance associated protein0102
Nuclear receptor subfamily 1 group I member 20011
Nuclear receptor subfamily 1 group I member 20011
Indoleamine 2,3-dioxygenase 10203
Ubiquitin-like modifier activating enzyme 20101
SUMO1 activating enzyme subunit 10101
ubiquitin-like modifier-activating enzyme 10101
SUMO-conjugating enzyme UBC90101
ubiquitin-conjugating enzyme E2 variant 1 isoform a0101
Complement C1r subcomponent0101
Coagulation factor X0101
Coagulation factor XII0101
Cationic trypsin0101
Interstitial collagenase0202
Serine protease hepsin0202
Cathepsin D0101
Trypsin-10101
72 kDa type IV collagenase0101
Complement C1s subcomponent0101
Neutrophil collagenase0101
Collagenase 30101
Hepatocyte growth factor activator0213
Suppressor of tumorigenicity 14 protein0101
Vasopressin V1b receptor0101
Vasopressin V2 receptor 0101
Chain A, Penicillin Amidohydrolase0101
Chain B, Penicillin Amidohydrolase0101
Chain A, Penicillin Amidohydrolase0101
Chain B, Penicillin Amidohydrolase0101
Chain A, Penicillin Amidohydrolase0101
Chain B, Penicillin Amidohydrolase0101
Chain A, Penicillin Amidohydrolase0101
Chain B, Penicillin Amidohydrolase0101
Chain A, Penicillin Amidohydrolase0101
Chain B, Penicillin Amidohydrolase0101
Chain A, Penicillin Amidohydrolase0101
Chain B, Penicillin Amidohydrolase0101
Chain A, Penicillin Amidohydrolase0101
Chain B, Penicillin Amidohydrolase0101
Chain A, Lysozyme0011
Chain A, Lysozyme0011
Chain A, Lysozyme0011
Chain A, Lysozyme0011
Chain A, Ferritin light chain0022
Chain A, Ferritin light chain0022
Chain A, Ferritin light chain0022
Chain A, Ferritin light chain0022
Chain A, Ferritin light chain0022
Chain A, Ferritin light chain0022
Chain A, Ferritin light chain0022
Endolysin0011
Sulfotransferase 1A1 0001
mu-type opioid receptor isoform MOR-10011
5-hydroxytryptamine receptor 2A0011
Chain D, PROTEIN (PHOSPHOGLYCERATE MUTASE 1)0101
Chain A, PROTEIN (PHOSPHOGLYCERATE MUTASE 1)0101
Chain A, Beta-arrestin 10011
XBP10101
nuclear factor NF-kappa-B p105 subunit isoform 11001
DNA damage-inducible transcript 3 protein0101
Voltage-dependent T-type calcium channel subunit alpha-1G0011
Ubiquitin carboxyl-terminal hydrolase 10101
D0202
D(3) dopamine receptor0202
D(1B) dopamine receptor0101
D(4) dopamine receptor0101
WD repeat-containing protein 480101
Histamine H4 receptor0101
nuclear receptor subfamily 0 group B member 10101
steroidogenic factor 10101
Tubulin alpha-1A chain0213
Tubulin beta chain0213
Regulatory protein E20011
Regulatory protein E20011
Tubulin beta-4A chain0113
Tubulin beta chain0113
Tubulin alpha-3C chain0113
Tubulin alpha-1B chain0113
Tubulin alpha-4A chain0113
Tubulin beta-4B chain0113
Tubulin beta-3 chain0113
Tubulin beta-2A chain0113
Tubulin beta-8 chain0113
Calcium-activated potassium channel subunit alpha-10101
Tubulin alpha-3E chain0113
Tubulin alpha-1A chain0113
Tubulin alpha-1C chain0113
Tubulin beta-6 chain0113
Tubulin beta-2B chain0113
Tubulin beta-1 chain0113
Alpha-1A adrenergic receptor0112
Solute carrier family 22 member 30101
Beta-casein0101
5-hydroxytryptamine receptor 1A0202
Ribosyldihydronicotinamide dehydrogenase [quinone]0101
Alpha-1A adrenergic receptor0202
Alpha-1B adrenergic receptor0101
Alpha-2A adrenergic receptor0101
Alpha-mannosidase 2C10011
Bromodomain-containing protein 20202
5-hydroxytryptamine receptor 1D0101
5-hydroxytryptamine receptor 1B0314
Alpha-2B adrenergic receptor0101
3-oxo-5-alpha-steroid 4-dehydrogenase 20101
Type-1 angiotensin II receptor0101
Alpha-2C adrenergic receptor0101
Alpha-2A adrenergic receptor0101
Alpha-2A adrenergic receptor0101
luciferase0001
Progesterone receptor0517
Glucocorticoid receptor0112
Glucocorticoid receptor0011
Glutamine synthetase0011
Histamine H1 receptor0011
Nociceptin receptor0011
heat shock protein 90, putative0001
UDP-glucuronosyltransferase 1A90002
UDP-glucuronosyltransferase 1A80001
Endothelin-1 receptor0112
Neuromedin-K receptor0011
Type-1 angiotensin II receptor0112
Cholecystokinin receptor type A0112
5-hydroxytryptamine receptor 70112
Nuclear receptor subfamily 2 group E member 10022
Pyridoxal kinase0001
Receptor-type tyrosine-protein phosphatase beta0001
Low molecular weight phosphotyrosine protein phosphatase0101
Trans-sialidase0101
Trans-sialidase0101
Chain A, dATP pyrophosphohydrolase0101
Chain A, Adenylate cyclase type 50101
Chain B, Adenylate cyclase type 20101
Solute carrier family 22 member 10101
Solute carrier family 22 member 20101
Histidine-rich protein PFHRP-II0101
Solute carrier family 22 member 10203
Estrogen receptor beta0001
Inhibitor of nuclear factor kappa-B kinase subunit beta0001
5'-AMP-activated protein kinase subunit beta-20001
Polymerase acidic protein0011
Tyrosine-protein phosphatase YopH0101
Prolyl 4-hydroxylase subunit alpha-10101
Tyrosine-protein phosphatase non-receptor type 10103
Estrogen receptor0001
Acetylcholinesterase0101
Cystathionine gamma-lyase0101
5'-AMP-activated protein kinase subunit gamma-10001
5'-AMP-activated protein kinase catalytic subunit alpha-20001
Xanthine dehydrogenase/oxidase0101
5'-AMP-activated protein kinase catalytic subunit alpha-10001
Ubiquitin-like domain-containing CTD phosphatase 10101
5'-AMP-activated protein kinase subunit gamma-30001
5'-AMP-activated protein kinase subunit gamma-20001
5'-AMP-activated protein kinase subunit beta-10001
Pyruvate kinase PKM0011
Neutral amino acid transporter A0101
Neutral amino acid transporter B(0)0101
Amino acid transporter0101
Chain A, Mineralocorticoid receptor0101
Chain A, Mineralocorticoid receptor0101
Hematopoietic prostaglandin D synthase0101
Chain A, CES1 protein0101
Spike glycoprotein0011
Replicase polyprotein 1ab0011
Transmembrane protease serine 20011
Serine/threonine-protein kinase D30101
Lysosomal acid glucosylceramidase0011
Protein kinase C gamma type0101
Protein kinase C alpha type0101
Protein kinase C beta type0101
Estrogen receptor0012
Protein kinase C delta type0101
Protein kinase C epsilon type0101
Protein kinase C zeta type0101
Replicase polyprotein 1a0011
Replicase polyprotein 1ab0011
Replicase polyprotein 1ab0011
Steroid hormone receptor ERR10101
Transcriptional activator protein LuxR0101
Protein kinase C alpha type0101
Protein kinase C eta type0101
Substance-P receptor0202
Adenosine receptor A10202
Melanocortin receptor 40202
Melanocortin receptor 50202
Protein kinase C iota type0101
Melanocortin receptor 30202
Estrogen-related receptor gamma0101
Protein kinase C gamma type0101
Protein kinase C beta type0101
Phospholipase D1 0101
Protein kinase C epsilon type0101
Protein kinase C theta type0101
Protein kinase C zeta type0101
Protein kinase C delta type0101
Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform0101
Platelet-activating factor acetylhydrolase0101
Phospholipase D10101
Serine/threonine-protein kinase D10101
Estrogen receptor beta0012
Protein kinase C eta type0101
Emopamil-binding protein-like0101
Angiotensin-converting enzyme 2 0011
7-dehydrocholesterol reductase0112
Protein kinase C theta type0101
Urokinase-type plasminogen activator0101
Chain A, Nuclear Receptor ROR-beta0101
Ornithine decarboxylase0001
Ornithine decarboxylase0001
Retinoic acid receptor alpha0227
Retinoic acid receptor beta0227
Retinoic acid receptor alpha0123
Retinoic acid receptor gamma 0227
Retinoic acid receptor gamma0123
Retinoic acid receptor RXR-alpha0224
Retinoic acid receptor beta0123
Cellular retinoic acid-binding protein 20011
Mitogen-activated protein kinase 10101
Retinoic acid receptor RXR-alpha0123
Retinoic acid receptor RXR-beta0224
Retinoic acid receptor RXR-beta0123
Retinoic acid receptor RXR-gamma0123
Nuclear receptor ROR-alpha0101
Cellular retinoic acid-binding protein 10102
Retinoic acid receptor RXR-gamma0224
Cellular retinoic acid-binding protein 10011
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 10213
Indoleamine 2,3-dioxygenase 20101
Nuclear receptor ROR-beta0101
Chain A, Trp Rna-binding Attenuation Protein0011
Chain K, Trp Rna-binding Attenuation Protein0011
Chain B, tryptophanyl-tRNA synthetase0011
Chain C, Tryptophanyl-tRNA synthetase II0011
Alkaline phosphatase, tissue-nonspecific isozyme0101
Intestinal-type alkaline phosphatase0101
Tryptophan 2,3-dioxygenase0102
Tryprostatin B synthase0001
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase0011
Phospholipase A-2-activating protein0101
Cocaine esterase0101
Aldo-keto reductase family 1 member A10101
UDP-glucuronosyltransferase 1-60001
Liver carboxylesterase 10101
Aldo-keto reductase family 1 member A10101
Aldo-keto reductase family 1 member A10101
Aldo-keto reductase family 1 member B70101
NAD-dependent protein deacylase sirtuin-5, mitochondrial0101
D-alanyl-D-alanine dipeptidase0101
Transporter0101
Cytochrome P450 2E10101
Cystic fibrosis transmembrane conductance regulator0011
Proprotein convertase subtilisin/kexin type 70101
Vitamin K epoxide reductase complex subunit 1-like protein 10101
Vitamin K epoxide reductase complex subunit 10101
Protease 0101
Vitamin K epoxide reductase complex subunit 1-like protein 10101
Vitamin K epoxide reductase complex subunit 1 0202
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]