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tinidazole and Amebiasis, Intestinal

tinidazole has been researched along with Amebiasis, Intestinal in 33 studies

Tinidazole: A nitroimidazole alkylating agent that is used as an antitrichomonal agent against TRICHOMONAS VAGINALIS; ENTAMOEBA HISTOLYTICA; and GIARDIA LAMBLIA infections. It also acts as an antibacterial agent for the treatment of BACTERIAL VAGINOSIS and anaerobic bacterial infections.
tinidazole : 1H-imidazole substituted at C-1 by a (2-ethylsulfonyl)ethyl group, at C-2 by a methyl group and at C-5 by a nitro group. It is used as an antiprotozoal, antibacterial agent.

Research Excerpts

ExcerptRelevanceReference
"Intestinal amoebiasis: of 502 patients, comprising 458 adults and 44 children, with symptomatic intestinal amoebiasis who received tinidazole as a single daily dose on 2 to 3 consecutive days, 477 (95%) were parasitologically cured with complete or marked improvement in symptoms."5.26Tinidazole in the treatment of trichomoniasis, giardiasis and amoebiasis. Report of a multicentre study. ( Apte, VV; Packard, RS, 1978)
"To find out if the administration of tinidazole, in patients with acute leukemia and negative coprological test, at the beginning of the CT, decreases the incidence of amoebic colitis during the induction to remission."3.91[Eficacia del tinidazol en la profilaxis terapéutica de la colitis amebiana en pacientes con leucemia aguda de novo que reciben quimioterapia intensiva]. ( Alvarado-Ibarra, M; Álvarez-Vera, JL; Arana-Luna, LL; de la Peña-Celaya, JA; Espitia-Ríos, ME; Mena-Zepeda, V; Ortiz-Zepeda, M; Zúñiga, JMP, 2019)
"Sixty adult patients with symptomatic intestinal amoebiasis and with Entamoeba histolytica present in stools were allocated at random to treatment with tinidazole or metronidazole, both administered in a dose of 2 g once daily for 3 consecutive days."2.64Tinidazole and metronidazole in the treatment of intestinal amoebiasis. ( Devi, CS; Lavakusulu, D; Swami, B, 1977)
"Tinidazole was better tolerated compared with metronidazole."2.64Short course of single daily dosage treatment with tinidazole and metronidazole in intestinal amoebiasis: a comparative study. ( Kumar, S; Singh, G, 1977)
"Tinidazole was given in a single dose of 2g a day for 2 days to 17 adults, and in a single dose of 50mg/kg bodyweight daily for 3 days to 4 children, with symptomatic, but not severe, intestinal amoebiasis."2.64Treatment of symptomatic intestinal amoebiasis with tinidazole. ( Garcia, EG, 1978)
"Sixty patients with symptomatic intestinal amoebiasis were treated for 3 days with a single dose of 2 g of either tinidazole or metronidazole respectively by random order."2.64A comparison of a short course of single daily dosage therapy of tinidazole with metronidazole in intestinal amoebiasis. ( Gupta, RC; Misra, NP, 1977)
"Tinidazole was tolerated well in children and proved to be a valuable new amoebicidal drug."2.64Clinical evaluation in tinidazole in amoebiasis in children. ( Ahmed, T; Ali, F; Sarwar, SG, 1976)
"Adequate therapy for amoebic colitis is necessary to reduce illness, prevent development of complicated disease and extraintestinal spread, and decrease transmission."2.61Antiamoebic drugs for treating amoebic colitis. ( Dans, LF; Gonzales, MLM; Sio-Aguilar, J, 2019)
"Amoebic dysentery is caused by the protozoan parasite Entamoeba histolytica."2.49Amoebic dysentery. ( Marie, C; Petri, WA, 2013)
"Amoebic dysentery is caused by the protozoan parasite Entamoeba histolytica."2.47Amoebic dysentery. ( Mackey-Lawrence, NM; Petri, WA, 2011)
"Adequate therapy for amoebic colitis is necessary to reduce the severity of illness, prevent development of complicated disease and extraintestinal spread, and decrease transmission."2.45Antiamoebic drugs for treating amoebic colitis. ( Dans, LF; Gonzales, ML; Martinez, EG, 2009)
"Amoebic dysentery is caused by the protozoan parasite Entamoeba histolytica."2.44Amoebic dysentery. ( Dans, LF; Martínez, EG, 2007)
"Tinidazole was indicated, 2 g/day for 5 days in the first week of CT started."1.51Tinidazole efficacy for amebic colitis therapeutic prophylaxis in patients with de novo acute leukemia receiving intensive chemotherapy. ( Alvarado-Ibarra, M; Álvarez-Vera, JL; Arana-Luna, LL; Espitia-Ríos, ME; Mena-Zepeda, V; Ortiz-Zepeda, M; Peña-Celaya, JA; Zúñiga, JMP, 2019)
"Intestinal amoebiasis: of 502 patients, comprising 458 adults and 44 children, with symptomatic intestinal amoebiasis who received tinidazole as a single daily dose on 2 to 3 consecutive days, 477 (95%) were parasitologically cured with complete or marked improvement in symptoms."1.26Tinidazole in the treatment of trichomoniasis, giardiasis and amoebiasis. Report of a multicentre study. ( Apte, VV; Packard, RS, 1978)

Research

Studies (33)

TimeframeStudies, this research(%)All Research%
pre-199022 (66.67)18.7374
1990's0 (0.00)18.2507
2000's3 (9.09)29.6817
2010's8 (24.24)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Fabio, PF1
Fields, TL1
Lin, Y1
Burden, EJ1
Carvajal, S1
Murdock, KC1
Lang, SA1
Arana-Luna, LL2
Álvarez-Vera, JL2
Peña-Celaya, JA1
Mena-Zepeda, V2
Ortiz-Zepeda, M2
Espitia-Ríos, ME2
Zúñiga, JMP2
Alvarado-Ibarra, M2
Gonzales, MLM1
Dans, LF3
Sio-Aguilar, J1
de la Peña-Celaya, JA1
Marie, C1
Petri, WA3
Gonzales, ML1
Martinez, EG2
Hwang, EW1
Cheung, L1
Mojtahed, A1
Cartwright, CA1
Mackey-Lawrence, NM1
Basilisco, G1
Grande, R1
Ferrero, S1
Hung, CC1
Chang, SY1
Ji, DD1
Bercu, TE1
Behm, JW1
Knight, R1
Wolfe, MS1
Pehrson, P1
Bengtsson, E1
Jankó, M1
Vidor, E1
Swami, B1
Lavakusulu, D1
Devi, CS1
Singh, G1
Kumar, S1
Garcia, EG1
Misra, NP4
Bakshi, JS1
Ghiara, JM1
Nanivadekar, AS1
Gupta, RC1
Apte, VV1
Packard, RS1
Welch, JS1
Rowsell, BJ1
Freeman, C1
Coulter, JR1
Turner, JV1
Scragg, JN2
Rubidge, CJ1
Proctor, EM2
Ahmed, T1
Ali, F1
Sarwar, SG1
Laiq, SM2
Gaber, A1
Adbel Meguid, M1
Saif, M1
Khalil, HM1
Fawzy, AF1
Sarwat, MA1
Bassily, S1
Farid, Z1
el-Masry, NA1
Mikhail, EM1

Reviews

7 reviews available for tinidazole and Amebiasis, Intestinal

ArticleYear
Antiamoebic drugs for treating amoebic colitis.
    The Cochrane database of systematic reviews, 2019, 01-09, Volume: 1

    Topics: Amebicides; Animals; Drug Therapy, Combination; Dysentery, Amebic; Entamoeba histolytica; Humans; Me

2019
Amoebic dysentery.
    BMJ clinical evidence, 2013, Aug-30, Volume: 2013

    Topics: Administration, Oral; Diarrhea; Dysentery, Amebic; Entamoeba histolytica; Feces; Humans; Metronidazo

2013
Antiamoebic drugs for treating amoebic colitis.
    The Cochrane database of systematic reviews, 2009, Apr-15, Issue:2

    Topics: Amebicides; Animals; Drug Therapy, Combination; Dysentery, Amebic; Entamoeba histolytica; Humans; Me

2009
Amoebic dysentery.
    BMJ clinical evidence, 2007, Jan-01, Volume: 2007

    Topics: Administration, Oral; Antibodies, Protozoan; Diarrhea; Dysentery, Amebic; Entamoeba histolytica; Fec

2007
Amoebic dysentery.
    BMJ clinical evidence, 2011, Jan-13, Volume: 2011

    Topics: Administration, Oral; Diarrhea; Dysentery, Amebic; Entamoeba histolytica; Humans; Incidence; Iodoqui

2011
Amebic colitis: new insights into pathogenesis and treatment.
    Current gastroenterology reports, 2007, Volume: 9, Issue:5

    Topics: Adolescent; Adult; Age Distribution; Animals; Bangladesh; Child; Child, Preschool; Developing Countr

2007
The treatment of intestinal protozoan infections.
    The Medical clinics of North America, 1982, Volume: 66, Issue:3

    Topics: Amebicides; Antimalarials; Antiprotozoal Agents; Balantidiasis; Chloroquine; Coccidiosis; Dientamoeb

1982

Trials

11 trials available for tinidazole and Amebiasis, Intestinal

ArticleYear
Treatment of non-invasive amoebiasis--a comparison between tinidazole and metronidazole.
    Annals of tropical medicine and parasitology, 1984, Volume: 78, Issue:5

    Topics: Adolescent; Adult; Clinical Trials as Topic; Dysentery, Amebic; Female; Humans; Male; Metronidazole;

1984
Tinidazole and metronidazole in the treatment of intestinal amoebiasis.
    Current medical research and opinion, 1977, Volume: 5, Issue:2

    Topics: Adult; Clinical Trials as Topic; Dysentery, Amebic; Female; Humans; Male; Metronidazole; Nitroimidaz

1977
Short course of single daily dosage treatment with tinidazole and metronidazole in intestinal amoebiasis: a comparative study.
    Current medical research and opinion, 1977, Volume: 5, Issue:2

    Topics: Adolescent; Adult; Clinical Trials as Topic; Drug Administration Schedule; Dysentery, Amebic; Female

1977
Treatment of symptomatic intestinal amoebiasis with tinidazole.
    Drugs, 1978, Volume: 15 Suppl 1

    Topics: Adult; Child; Clinical Trials as Topic; Dysentery, Amebic; Humans; Nitroimidazoles; Tinidazole

1978
A comparative study of tinidazole and metronidazole as a single daily dose for three days in symptomatic intestinal amoebiasis.
    Drugs, 1978, Volume: 15 Suppl 1

    Topics: Adolescent; Adult; Clinical Trials as Topic; Dysentery, Amebic; Feces; Humans; Metronidazole; Middle

1978
How does tinidazole compare with metronidazole? A summary report of Indian trials in amoebiasis and giardiasis.
    Drugs, 1978, Volume: 15 Suppl 1

    Topics: Adult; Amebiasis; Child; Clinical Trials as Topic; Dysentery, Amebic; Female; Giardiasis; Humans; In

1978
A comparison of a short course of single daily dosage therapy of tinidazole with metronidazole in intestinal amoebiasis.
    The Journal of international medical research, 1977, Volume: 5, Issue:6

    Topics: Adolescent; Adult; Dysentery, Amebic; Female; Humans; Male; Metronidazole; Middle Aged; Nitroimidazo

1977
Tinidazole in treatment of acute amoebic dysentery in children.
    Archives of disease in childhood, 1976, Volume: 51, Issue:5

    Topics: Acute Disease; Child; Child, Preschool; Clinical Trials as Topic; Dysentery, Amebic; Humans; Infant;

1976
Clinical evaluation in tinidazole in amoebiasis in children.
    Archives of disease in childhood, 1976, Volume: 51, Issue:5

    Topics: Bangladesh; Child; Child, Preschool; Clinical Trials as Topic; Drug Evaluation; Dysentery, Amebic; F

1976
Treatment of intestinal E. histolytica and G. lamblia with metronidazole, tinidazole and ornidazole: a comparative study.
    The Journal of tropical medicine and hygiene, 1987, Volume: 90, Issue:1

    Topics: Clinical Trials as Topic; Dysentery, Amebic; Giardiasis; Humans; Intestinal Diseases, Parasitic; Mal

1987
Comparative trial of tinidazole and metronidazole in intestinal amebiasis.
    Current therapeutic research, clinical and experimental, 1974, Volume: 16, Issue:12

    Topics: Adolescent; Adult; Animals; Antiprotozoal Agents; Clinical Trials as Topic; Dysentery, Amebic; Feces

1974

Other Studies

15 other studies available for tinidazole and Amebiasis, Intestinal

ArticleYear
Bisamidines of 2,6-diaminoanthraquinone as antiamebic agents.
    Journal of medicinal chemistry, 1978, Volume: 21, Issue:3

    Topics: Amebiasis; Amebicides; Amidines; Animals; Anthraquinones; Cricetinae; Dysentery, Amebic; Entamoeba h

1978
Tinidazole efficacy for amebic colitis therapeutic prophylaxis in patients with de novo acute leukemia receiving intensive chemotherapy.
    Gaceta medica de Mexico, 2019, Volume: 155, Issue:Suppl 1

    Topics: Adolescent; Adult; Aged; Amebicides; Antineoplastic Combined Chemotherapy Protocols; Dysentery, Ameb

2019
[Eficacia del tinidazol en la profilaxis terapéutica de la colitis amebiana en pacientes con leucemia aguda de novo que reciben quimioterapia intensiva].
    Gaceta medica de Mexico, 2019, Volume: 155, Issue:Suppl 1

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Colitis; Dysentery, Amebic; Female; Humans; Leukemia

2019
Relapse of intestinal and hepatic amebiasis after treatment.
    Digestive diseases and sciences, 2011, Volume: 56, Issue:3

    Topics: Amebicides; Antidiarrheals; Colonoscopy; Drug Therapy, Combination; Dysentery, Amebic; Humans; Iodoq

2011
Amebic colitis in Italy after Christmas.
    Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver, 2012, Volume: 44, Issue:4

    Topics: Amebicides; Dysentery, Amebic; Egypt; Entamoeba histolytica; Humans; Male; Middle Aged; Paromomycin;

2012
Entamoeba histolytica infection in men who have sex with men.
    The Lancet. Infectious diseases, 2012, Volume: 12, Issue:9

    Topics: Antiprotozoal Agents; Dysentery, Amebic; Entamoeba histolytica; Entamoebiasis; Homosexuality, Male;

2012
The chemotherapy of amoebiasis.
    The Journal of antimicrobial chemotherapy, 1980, Volume: 6, Issue:5

    Topics: Acetanilides; Amebiasis; Amebicides; Arsenicals; Carrier State; Chloroquine; Dysentery, Amebic; Emet

1980
[Tinidazole therapy of intestinal amebiasis].
    Orvosi hetilap, 1981, Jul-12, Volume: 122, Issue:28

    Topics: Dysentery, Amebic; Humans; Nitroimidazoles; Tinidazole

1981
Tinidazole in the treatment of trichomoniasis, giardiasis and amoebiasis. Report of a multicentre study.
    Drugs, 1978, Volume: 15 Suppl 1

    Topics: Adult; Amebiasis; Child; Dysentery, Amebic; Giardiasis; Humans; Liver Abscess, Amebic; Nitroimidazol

1978
Treatment of intestinal amoebiasis and giardiasis; efficacy of metronidazole and tinidazole compared.
    The Medical journal of Australia, 1978, May-06, Volume: 1, Issue:9

    Topics: Child; Drug Administration Schedule; Dysentery, Amebic; Giardiasis; Humans; Metronidazole; Nitroimid

1978
Treatment of amoebiasis and giardiasis.
    The Medical journal of Australia, 1978, Sep-09, Volume: 2, Issue:6

    Topics: Child; Dysentery, Amebic; Giardiasis; Humans; Metronidazole; Neoplasms; Nitroimidazoles; Research De

1978
Tinidazole treatment of acute amebic dysentery in children.
    The American journal of tropical medicine and hygiene, 1977, Volume: 26, Issue:4

    Topics: Acute Disease; Child; Child, Preschool; Dysentery, Amebic; Humans; Infant; Nitroimidazoles; Tinidazo

1977
Tinidazole in intestinal amoebiasis.
    The Journal of the Association of Physicians of India, 1976, Volume: 24, Issue:4

    Topics: Adult; Dysentery, Amebic; Entamoebiasis; Female; Humans; Male; Metronidazole; Nitroimidazoles; Tinid

1976
Treatment of acute intestinal amoebiasis with tinidazole.
    The Journal of the Egyptian Medical Association, 1975, Volume: 58, Issue:7-8

    Topics: Acute Disease; Adolescent; Adult; Dysentery, Amebic; Female; Humans; Male; Middle Aged; Nitroimidazo

1975
Trials of furazol and some other drugs in intestinal amoebiasis.
    Journal of the Egyptian Society of Parasitology, 1987, Volume: 17, Issue:2

    Topics: Amebicides; Dysentery, Amebic; Furans; Furazolidone; Humans; Iodoquinol; Metronidazole; Tinidazole

1987