Compounds > org 6582
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org 6582

Description

Org 6582: inhibits 3-hydroxytryptamine reuptake; RN & NM refer to HCl [MeSH]

Cross-References

ID SourceID
PubMed CID133082267
MeSH IDM0058965

Synonyms (8)

Synonym
org-6582
org 6582
5,9-methanobenzocycloocten-11-amine, 2-chloro-5,6,9,10-tetrahydro-, hydrochloride
s7vk4kin4b ,
unii-s7vk4kin4b
8-chloro-11-anti-aminobenzo(b)bicyclo(3.3.1)nona-3,6a(10a)-diene.hcl
5,9-methanobenzocycloocten-11-amine, 2-chloro-5,6,9,10-tetrahydro-, hydrochloride (1:1), (5r,9r,11s)-rel-
d,l-8-chloro-11-anti-amino-benzo-(b)-bicycle-(3.3.1)-nona-3,6a-(10a)-diene hydrochloride

Research

Studies (6)

TimeframeStudies, This Drug (%)All Drugs %
pre-19906 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other6 (100.00%)84.16%
SubstanceStudiesClassesRolesFirst YearLast YearAverage AgeRelationship StrengthTrialspre-19901990's2000's2010'spost-2020
clomipramine
1
dibenzoazepineanticoronaviral agent;
antidepressant;
EC 1.8.1.12 (trypanothione-disulfide reductase) inhibitor;
serotonergic antagonist;
serotonergic drug;
serotonin uptake inhibitor		1977197747.0low010000
clonidine
1
clonidine;
imidazoline		1981198143.0low010000
desipramine
2
dibenzoazepine;
secondary amino compound		adrenergic uptake inhibitor;
alpha-adrenergic antagonist;
antidepressant;
cholinergic antagonist;
drug allergen;
EC 3.1.4.12 (sphingomyelin phosphodiesterase) inhibitor;
EC 3.4.21.26 (prolyl oligopeptidase) inhibitor;
H1-receptor antagonist;
serotonin uptake inhibitor		1977198145.0medium020000
p-chloroamphetamine
1
1976197648.0low010000
fluoxetine
1
(trifluoromethyl)benzenes;
aromatic ether;
secondary amino compound		1981198143.0low010000
mianserin
2
dibenzoazepineadrenergic uptake inhibitor;
alpha-adrenergic antagonist;
antidepressant;
EC 3.4.21.26 (prolyl oligopeptidase) inhibitor;
geroprotector;
H1-receptor antagonist;
histamine agonist;
sedative;
serotonergic antagonist		1981198342.0medium020000
nisoxetine
1
aromatic ether;
secondary amino compound		adrenergic uptake inhibitor;
antidepressant		1981198143.0low010000
tyramine
1
monoamine molecular messenger;
primary amino compound;
tyramines		EC 3.1.1.8 (cholinesterase) inhibitor;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
neurotransmitter		1977197747.0low010000
reserpine
2
alkaloid ester;
methyl ester;
yohimban alkaloid		adrenergic uptake inhibitor;
antihypertensive agent;
EC 3.4.21.26 (prolyl oligopeptidase) inhibitor;
environmental contaminant;
first generation antipsychotic;
plant metabolite;
xenobiotic		1976198344.5medium020000
metaraminol
1
phenylethanolaminesalpha-adrenergic agonist;
sympathomimetic agent;
vasoconstrictor agent		1976197648.0low010000
tetrabenazine
1
benzoquinolizine;
cyclic ketone;
tertiary amino compound		1976197648.0low010000
methoxyhydroxyphenylglycol
1
methoxybenzenes;
phenols		1981198143.0low010000
iprindole
1
indoles1981198143.0low010000
ConditionIndicatedStudiesFirst YearLast YearAverage AgeRelationship StrengthTrialspre-19901990's2000's2010'spost-2020
Hyperactivity, Motor0
1
1983198341.0high010000