Page last updated: 2024-09-27

Hyperphosphatemia

A condition of abnormally high level of PHOSPHATES in the blood, usually significantly above the normal range of 0.84-1.58 mmol per liter of serum.

Synonyms(1)

Synonym
Hyperphosphatemia

Research Excerpts

Overview

ExcerptReference
"Hyperphosphatemia is one of the more prevalent metabolic disturbances in kidney failure."( Burke, SK, 2008)
"Hyperphosphatemia is independently associated with an increased risk of death among dialysis patients."( Akçiçek, F; Akpolat, T; Arinsoy, T; Ataman, R; Ateş, K; Bozfakioğlu, S; Camsari, T; Dimitriades, AC; Dombros, NA; Ersoy, FF; Evaggelos, DM; Gültekin, M; Karayaylali, I; Katopodis, KP; Oreopoulos, DG; Ozener, C; Passadakis, PS; Stathakis, CP; Süleymanlar, G; Tam, P; Tsakiris, DJ; Utaş, C; Vlachojannis, GJ; Wu, G; Yavuz, A; Yavuz, M; Yilmaz, ME, 2008)
"Hyperphosphatemia is highly prevalent in dialysis patients and may be associated with immune dysfunction."( Briggs, WA; Fink, NE; Jaar, BG; Melamed, ML; Plantinga, LC; Powe, NR, 2008)
"Hyperphosphatemia is an independent risk factor for mortality in ESRD, but factors regulating phosphate clearance on peritoneal dialysis (PD) are incompletely understood."( Badve, SV; Burns, KD; Knoll, GA; McCormick, BB; Zimmerman, DL, 2008)
"Hyperphosphatemia is a complication that appears in the early stages of chronic kidney disease (CKD) and that has been shown to have serious consequences in kidney disease patients."( Fernandez Giraldez, E; Sánchez González, MC; Valdivielso Revilla, JM, 2008)
"In uremic patients, hyperphosphatemia is associated with cardiovascular calcification and increased cardiovascular mortality."( Bellinghieri, G; Calò, LA; Comelli, MC; Davis, PA; Granata, A; Monardo, P; Musolino, R; Santoro, D; Savica, R; Savica, V, 2009)
"Hyperphosphatemia is an important modifiable risk factor in the dialysis population because it is linked to increased mortality."( Sampathkumar, K, 2009)
"Hyperphosphatemia is treated by dietary limitation of phosphorus ingestion and by phosphate binders, but only half of ESRD patients fall within the range of K/DOQI guidelines."( Bellinghieri, G; Calò, LA; Mallamace, A; Monardo, P; Muraca, U; Santoro, D; Savica, V, 2009)
"Hyperphosphatemia is associated with an increased risk of cardiovascular morbidity and mortality."( Guidi, GC; Lippi, G; Montagnana, M; Salvagno, GL; Targher, G, 2009)
"Hyperphosphatemia is an almost universal finding in patients with end-stage renal disease and is associated with increased all-cause mortality, cardiovascular mortality, and vascular calcification."( Tanaka, M, 2009)
"Hyperphosphatemia is a major problem in these patients with advanced stage of CKD."( Yokoyama, K, 2009)
"Since hyperphosphatemia is an established risk factor for not only secondary hyperparathyroidism, but also cardiovascular mortality in these patients, the adequate control of serum phosphorus is necessary."( Akizawa, T; Mizobuchi, M; Sanada, D, 2009)
"Hyperphosphatemia is recognized as a principal mineral disorder in chronic kidney disease (CKD) that leads to the development of secondary hyperparathyroidism."( Barton Pai, A; Conner, TA; McQuade, CR, 2009)
"Hyperphosphatemia is an inevitable consequence of end-stage chronic kidney disease and is present in the majority of dialysis patients."( Hutchison, AJ, 2009)
"Hyperphosphatemia is currently regarded as a key mortality risk predictor in late CKD stages and especially in patients on dialysis."( Ketteler, M, 2009)
"Hyperphosphatemia is highly prevalent in patients with chronic kidney disease (CKD), particularly in those with advanced or end-stage renal disease."( Pai, AB; Shepler, BM, 2009)
"Hyperphosphatemia is one of the key risk factors for aortic valve calcification."( Obrenović, R; Petrović, D; Stojimirović, B, 2009)
"Hyperphosphatemia is an independent risk factor for aortic valve calcification."( Obrenović, R; Petrović, D; Stojimirović, B, 2009)
"Hyperphosphatemia is a central characteristic feature of chronic kidney disease-mineral and bone disorder (CKD-MBD)."( Brandenburg, VM; Jahnen-Dechent, W; Ketteler, M, 2009)
"Hyperphosphatemia is a cardiovascular risk factor in patients with chronic kidney disease."( Arnlöv, J; Hagström, E; Ingelsson, E; Larsson, TE; Lind, L; Olauson, H; Sundström, J, 2010)
"Hyperphosphatemia is an independent risk factor for all-cause and cardiovascular mortality in hemodialysis (HD) patients."( Blankestijn, PJ; Bots, ML; Grooteman, MP; Lévesque, R; Nubé, MJ; Penne, EL; ter Wee, PM; van den Dorpel, MA; van der Weerd, NC, 2010)
"Hyperphosphatemia is common among patients receiving dialysis and is associated with increased mortality."( Culleton, B; Hemmelgarn, B; Klarenbach, S; Manns, BJ; Tonelli, M; Walsh, M, 2010)
"Although hyperphosphatemia is believed to be a risk factor for mortality and VC, no randomized trial was ever designed to demonstrate that lowering phosphate reduces mortality."( Moysés, RM; Raggi, P; Spiegel, DM; Vukicevic, S; Wesseling, K, 2010)
"Hyperphosphatemia is highly prevalent in hemodialysis (HD) and peritoneal dialysis (PD) patients and is a major risk factor for cardiovascular mortality."( Kuhlmann, MK, 2010)
"Hyperphosphatemia is associated with higher mortality and increased incidence of end-stage renal disease in patients with non-dialysis dependent CKD (NDD-CKD), but there has not been a concomitant assessment of mortality and progressive kidney disease that would also account for cumulative effects of hyperphosphatemia."( Anderson, JE; Kalantar-Zadeh, K; Kovesdy, CP, 2010)
"Hyperphosphatemia is a serious complication which has been linked with an increased risk of cardiovascular mortality in patients with chronic kidney disease."( Negi, S; Shigematsu, T, 2010)
"Hyperphosphatemia is not an expected consequence of dosing with amphotericin B formulations."( Bunch, TH; Jensen, GM; Laybourne, S; Wolf, S, 2010)
"Hyperphosphatemia is common among hemodialysis patients."( Brunelli, SM; Curhan, GC; Lynch, KE; Lynch, R, 2011)
"In uremic patients, hyperphosphatemia is associated with cardiovascular calcification and increased cardiovascular mortality."( Bellinghieri, G; Calò, LA; Davis, PA; Monardo, P; Muraca, U; Santoro, D; Santoro, G; Savica, V, 2011)
"Hyperphosphatemia is a well-recognized complication of chronic kidney disease, and phosphorus kinetics during hemodialysis (HD) remains a vague area of investigation."( Challa, AS; Dounousi, EC; Karasavvidou, DP; Katopodis, KP; Vlachou, IA, 2011)
"Hyperphosphatemia is the strongest independent risk factor for mortality in renal patients."( Brunner-Ziegler, S; Fröschl, B; Hiebinger, C; Zsifkovits, J, 2011)
"Because hyperphosphatemia is a major consequence of renal impairment, this study determines the in vivo effects of hyperphosphatemia in obesity."( Kato, S; Ohnishi, M; Razzaque, MS, 2011)
"Hyperphosphatemia is a common and potentially harmful condition in patients with end-stage kidney disease."( Keith, MS; Lok, CE; Morton, AR; Soroka, SD; Tolley, K; Vegter, S, 2012)
"Hyperphosphatemia is a serious complication which has been linked with an increased risk of cardiovascular mortality in patients with chronic kidney disease."( Hanba, Y; Masumoto, A; Moribata, M; Shigemathu, T, 2012)
"The control of hyperphosphatemia is an unmet need in dialysis care."( Dorigo, DM; Ruzany, F; Sampaio, MS; Suassuna, JH, 2012)
"Hyperphosphatemia is an infrequent, but potentially life-threatening complication of laxative application."( Deluggi, S; Ladenhauf, HN; Spreitzhofer, F; Stundner, O, 2012)
"Hyperphosphatemia is a significant risk factor for the development of ectopic calcification and coronary artery diseases in patients on hemodialysis (HD), and must be controlled with the use of phosphate binders."( Ahmadi, F; Khatami, MR; Lessan-Pezeshki, M; Shamekhi, F, 2012)
"The issue of hyperphosphatemia is prominent and needs further attention."( Chen, J; Chen, N; Chen, W; Chen, X; Ding, F; Fan, M; Gu, Y; He, L; Hou, F; Jia, Q; Kong, X; Liu, W; Mei, C; Ni, Z; Peng, L; Shi, W; Shu, G; Tang, X; Wang, H; Wang, L; Wang, M; Wu, H; Xing, C; Xiong, Z; Xu, D; Yu, X; Yuan, W; Zhang, J; Zhang, L; Zuo, L, 2012)
"Hyperphosphatemia is the most common complication among patients with chronic kidney disease."( Koreeda, D; Negi, S; Shigematsu, T; Yamanaka, S; Yashiro, M, 2012)
"Treatment of hyperphosphatemia is important in patients with CKD."( Hamada, Y; Usami, M, 2012)
"Hyperphosphatemia is a common disorder in patients with chronic kidney disease (CKD) , and may result in hyperparathyroidism and renal osteodystrophy."( Kido, S; Nomura, K; Sasaki, S; Segawa, H; Shiozaki, Y; Tatsumi, S, 2012)
"Hyperphosphatemia is a common complication in end-stage renal disease (ESRD) patients."( Choi, HY; Lee, HY; Lee, YK; Shin, SK, 2013)
"Hyperphosphatemia is a paradigmatic finding in late-stage chronic kidney disease (CKD) and consistently associated with adverse outcomes."( Biggar, PH; Ketteler, M, 2013)
"Hyperphosphatemia is associated with cardiovascular disease in patients with chronic kidney disease."( Akizawa, T; Kinugasa, E; Koiwa, F; Kondo, F; Kumata, C; Mizobuchi, M; Ogata, H; Ono, N; Uda, S; Yamazaki-Nakazawa, A, 2014)
"Hyperphosphatemia is a nearly universal complication of end-stage renal disease that is widely recognized as one of the most important and most challenging clinical targets to meet in the care of dialysis patients."( Isakova, T; Lenz, O; Pedraza, F; Waheed, AA, 2013)
"Hyperphosphatemia is one of the major factors associated with the development of vascular calcification in patients with chronic kidney disease (CKD)."( Goumenos, DS; Papachristou, E; Sonikian, M, 2013)
"Hyperphosphatemia is an important determinant of morbidity and mortality in patients with chronic kidney disease (CKD)."( Kitajima, M; Razzaque, MS; Saitoh, H; Saitoh, Y; Shimada, M; Shutto, Y; Yamabe, H, 2013)
"Hyperphosphatemia is a serious complication of late-stage chronic kidney disease (CKD), contributing to the increased cardiovascular morbidity and mortality seen in this patient group."( Lee, GJ; Marks, J, 2015)
"Hyperphosphatemia is common in the late stages of chronic kidney disease (CKD) and is associated with elevated parathormone levels, abnormal bone mineralization, extraosseous calcification and increased risk of cardiovascular events and death."( Del Vecchio, L; Locatelli, F; Pontoriero, G; Violo, L, 2014)
"Hyperphosphatemia is a prognostic factor for morbidity and mortality in chronic kidney disease."( Akizawa, T; Kameoka, C; Kaneko, Y; Kawasaki, S; Origasa, H, 2014)
"Hyperphosphatemia is a common complication in dialysis patients that can be treated by oral phosphate binders."( Chiang, SS; Lee, CT; Peng, YS; Shu, KH; Wu, IW; Wu, MJ; Wu, MS, 2015)
"Hyperphosphatemia is a prognostic factor for morbidity and mortality in chronic kidney disease."( Akizawa, T; Kameoka, C; Kaneko, Y; Kanoh, H; Origasa, H, 2014)
"Hyperphosphatemia is a major problem in these patients especially at advanced stages of CKD, and it is associated with cardiovascular and mineral complications in these patients."( Maizel, J; Massy, ZA, 2014)
"Hyperphosphatemia is strongly associated with cardiovascular morbidity and mortality in patients with chronic kidney disease."( Bosomworth, M; Costelloe, S; Fouque, D; Freeman, J; Keane, D; Lindley, E; Thompson, D, 2014)
"Nonetheless, hyperphosphatemia is a late marker of phosphate overload in humans."( Cozzolino, M; Cupisti, A; Galassi, A; Santoro, A, 2015)
"Spurious hyperphosphatemia is a relatively common phenomenon in patients with monoclonal gammopathy which can compromise patient safety."( Chakraborty, S; Kallner, A, 2015)
"Hyperphosphatemia is linked to the catabolic profile but the effect of renal impairment can't be ruled out."( Anker, SD; Doehner, W; Hudzik, B; Jankowska, EA; Kawecka, E; Kokocińska, D; Myrda, K; Niedziela, J; Nowak, J; Partyka, R; Poloński, L; Ponikowski, P; Rozentryt, P; Rywik, T; Szyguła, B; von Haehling, S, 2014)
"Hyperphosphatemia is an independent risk factor of cardiovascular events in the patients with chronic kidney disease."( Deng, B; Mohan, C; Peng, A; Qin, L; Tang, B; Wu, T, 2015)
"Hyperphosphatemia is common in end-stage renal disease and associates with mortality."( Browne, T; Cavanaugh, K; Ikizler, TA; Lewis, JB; Merighi, JR; Umanath, K; Umeukeje, EM; Victoroff, JN; Wallston, KA, 2015)
"Hyperphosphatemia is known to adversely affect mortality and quality of life in chronic kidney disease patients and has been shown to be involved not only in the onset and progression of secondary hyperparathyroidism but also in vascular calcification."( Iwatani, Y; Masumoto, AR; Mima, T; Moribata, MK; Nakashima, YM; Negi, S; Ohya, M; Shigematsu, T; Tatsuta, K; Yamanaka, S, 2015)
"Hyperphosphatemia is the most common metabolic complications of end-stage kidney disease (ESKD)."( Amiri, FS, 2015)
"Hyperphosphatemia is an independent predictor for cardiovascular and all-cause mortality in patients undergoing peritoneal dialysis (PD)."( Fang, W; Gu, AP; Jiang, N; Lin, AW; Ni, ZH; Qian, JQ; Yang, XX; Yuan, JZ, 2015)
"Hyperphosphatemia is an independent risk factor for CAC progression, and the serum phosphate level may be associated with protein intake and PD adequacy."( Ge, X; Hao, CM; Kuang, D; Shang, D; Tian, J; Xie, Q; Yan, H; Zhu, T, 2015)
"Hyperphosphatemia is a frequent complication of chronic kidney disease and is associated with increased mortality."( Lederer, SR; Schmid, H, 2015)
"Hyperphosphatemia is a common problem in patients with end-stage renal disease (ESRD) who are on maintenance hemodialysis (HD) and contributes to the development of secondary hyperparathyroidism and cardiovascular complications."( El Borolossy, R; El Hakim, I; El Wakeel, LM; Sabri, N, 2016)
"Hyperphosphatemia is thought to be a central-risk factor for CKD-MBD."( Masuda, M; Miyamoto, K; Segawa, H; Takeda, E; Taketani, Y; Tatsumi, S; Yamamoto, H; Yamanaka-Okumura, H, 2015)
"Hyperphosphatemia is associated with accelerated vascular endothelial dysfunction in patients with chronic kidney disease (CKD)."( Kang, X; Liu, JY; Mohan, C; Peng, A; Tang, B; Wu, T; Zhou, R, 2016)
"Hyperphosphatemia is common in chronic kidney disease (CKD) and is treated by dietary measures, dialysis techniques and/or phosphate binders."( Floege, J, 2016)
"Hyperphosphatemia is common in chronic kidney disease (CKD) and associated with mortality and morbidity."( Koiwa, F; Terao, A, 2017)
"Hyperphosphatemia is a hallmark of advanced chronic kidney disease (CKD) and associated with adverse outcomes."( Biggar, PH; Ketteler, M; Liangos, O, 2016)
"Hyperphosphatemia is associated with higher risk for cardiovascular mortality and morbidity along a gradient beginning at 5."( Copland, M; Komenda, P; McCullough, PA; Morfin, JA; Weinhandl, ED, 2016)
"Hyperphosphatemia is associated with all-cause mortality in hemodialysis (HD) patients and is managed by restricting dietary phosphate."( Adams, MA; Christilaw, E; Holden, RM; Lynch, SK; Nelson, SM; Sarabia, SR; Ward, EC, 2017)
"Hyperphosphatemia is common among patients with CKD stage 5D and is associated with morbidity and mortality."( Åstrand, M; Block, GA; Chertow, GM; Johansson, S; Knutsson, M; Langkilde, AM; Leonsson-Zachrisson, M; Rosenbaum, DP, 2017)
"Hyperphosphatemia is common in patients with chronic kidney disease (CKD) stages IV and V because of decreased phosphorus excretion."( Araujo, RM; Barretti, P; Caramori, JCT; Vogt, BP; Watanabe, MT, 2016)
"Hyperphosphatemia is common among recipients of maintenance dialysis and is associated with a higher risk of mortality and cardiovascular events."( Bosch, J; Gao, P; Garg, AX; Girard, L; Manns, BJ; Mazzetti, A; Parfrey, P; Rabbat, CG; Rathe-Skafel, A; Smyth, A; Tennankore, K; Tyrwhitt, J; Wald, R; Walsh, M; Yan, AT, 2017)
"Mild hyperphosphatemia is a putative risk factor for cardiovascular disease [CVD], loss of kidney function, and mortality."( Bostom, A; Carpenter, MA; Foster, MC; Gohh, R; House, AA; Ix, JH; Jacques, P; Kew, CE; Kim, SJ; Kusek, JW; Levey, AS; Merhi, B; Pesavento, TE; Pfeffer, M; Rao, M; Shireman, T; Smith, SR; Weiner, DE, 2017)
"Hyperphosphatemia is a late complication of chronic kidney disease (CKD)."( Bouajila, IA; De Seigneux, S; Martin, PY, 2017)
"Hyperphosphatemia is related to some pathologies, affecting vascular cell behavior."( Alcalde-Estevez, E; López-Ongil, S; Martínez-Miguel, P; Medrano, D; Naves-Diaz, M; Olmos, G; Rodríguez-Mañas, L; Rodríguez-Puyol, D; Ruiz-Torres, MP; Sosa, P, 2017)
"Hyperphosphatemia is one of the most notable features of chronic kidney disease (CKD)."( Bi, X; Huang, Y; Jiang, W; Liu, Y; Xiao, T; Xiong, J; Xu, X; Yu, Y; Zhang, B; Zhang, D; Zhang, J; Zhao, J, 2017)
"Hyperphosphatemia is associated with high mortality rate in patients on dialysis."( Alvares, VRC; Elias, RM; Moysés, RMA, 2018)
"Hyperphosphatemia is associated with mortality in patients with chronic kidney disease, and is common in critically ill patients with acute kidney injury (AKI); however, its clinical implication in these patients is unknown."( Chang, TI; Han, SH; Jhee, JH; Jung, SY; Kang, EW; Kang, SW; Kee, YK; Kim, H; Kwon, J; Park, JT; Park, S; Yoo, TH; Yoon, CY; Yun, HR, 2018)
"Hypo- and hyperphosphatemia are common in severe sepsis and septic shock."( Doepker, BA; Exline, MC; Miller, CJ; Murphy, CV; Phillips, G; Springer, AN, 2020)
"It is known that hyperphosphatemia is associated with coronary artery calcification."( Fujii, H; Hamano, T; Isaka, Y; Teramukai, S; Tsujimoto, Y, 2018)
"Hyperphosphatemia is common in patients on hemodialysis."( Li, H; Lu, X; Wang, F; Wang, S; Xiong, R; Zhang, J, 2018)
"Hyperphosphatemia is common in late stages of chronic kidney disease and is often associated with elevated parathormone levels, abnormal bone mineralization, extra-osseous calcification, and increased risk of cardiovascular events and death."( Carfagna, F; Del Vecchio, L; Locatelli, F; Pontoriero, G, 2018)
"Hyperphosphatemia is a common complication in patients with end-stage renal disease on hemodialysis."( Brauer, A; Maursetter, L; Singh, T; Waheed, S, 2019)
"Hyperphosphatemia is considered a decisive determinant of vascular calcification in CKD."( Alesutan, I; Amann, K; Eckardt, KU; Kuro-O, M; Lang, F; Pasch, A; Pieske, B; Voelkl, J, 2019)
"Hyperphosphatemia is a major risk factor leading to morbidity and mortality in patients with chronic kidney disease."( Han, M; Li, J; Li, Y; Liao, R; Maharjan, A; Su, B; Sun, S; Wang, L; Xiong, Y, 2019)
"Hyperphosphatemia is associated with increased risk for chronic kidney disease (CKD) progression and reduced antiproteinuric effects of renin-angiotensin system (RAS) blockers."( Aparicio, C; Bellasi, A; Cannata, A; Cozzolino, M; Ferrari, S; Kohan, DE; Lecchi, V; Mallamaci, F; Mazzaferro, S; Peraro, F; Perna, A; Perticucci, E; Remuzzi, G; Rotondi, S; Ruggenenti, P; Ruggiero, B; Tartaglione, L; Trillini, M; Tripepi, R; Villa, D; Zoccali, C, 2019)
"Background Hyperphosphatemia is a common consequence in end stage renal disease."( Chan, MW; Cheah, HM; Mohd Padzil, MB, 2019)
"Hyperphosphatemia is associated with vascular calcification and bone mineral disorders and is a major concern among patients with chronic kidney disease (CKD)."( Chin, HJ; Han, SS; Joo, KW; Kim, S; Kim, YS; Moon, H; Na, KY, 2019)
"Hyperphosphatemia is related to the risks of AKI, ESRD, and mortality, and it may therefore be necessary to monitor serum phosphorus level in hospitalized patients, irrespective of kidney function."( Chin, HJ; Han, SS; Joo, KW; Kim, S; Kim, YS; Moon, H; Na, KY, 2019)
"Hyperphosphatemia is a secondary issue associated with chronic kidney disorder."( Anand, A; Aoyagi, H, 2019)
"Hyperphosphatemia is a mineral bone-disease that increases cardiovascular complications and all-cause mortality in chronic kidney disease (CKD) patients."( Abediazar, S; Ardalan, M; Bahmanpoor, Z; Hosseiniyan Khatibi, SM; Majdi, H; Niknafs, B; Rahbar Saadat, Y; Zununi Vahed, S, 2020)
"The control of hyperphosphatemia is key to the management of chronic kidney disease mineral and bone disorder."( Bowles, M; Byrne, FN; Connolly, P; Earlie, J; Eustace, J; Gillman, B; Kearney, P; Kiely, M; Murphy, J; Reilly, EO; Rennick, T; Shiely, F, 2021)
"Hyperphosphatemia is associated with increased fibroblast growth factor 23 (FGF23), arterial calcification, and cardiovascular mortality."( Badve, SV; Block, GA; Boudville, N; Cameron, JD; Campbell, KL; Chen, SSM; Elder, GJ; Faull, RJ; Hawley, CM; Holt, SG; Hooi, LS; Jackson, D; Jardine, MJ; Johnson, DW; Kerr, PG; Lau, KK; Lioufas, NM; Narayan, O; Pascoe, EM; Pedagogos, E; Perkovic, V; Polkinghorne, KR; Pollock, CA; Reidlinger, D; Robison, L; Smith, ER; Toussaint, ND; Valks, A; Walker, RJ; Wang, AYM, 2020)
"Hyperphosphatemia is a risk factor for poor clinical outcomes in patients with kidney failure receiving maintenance dialysis."( Beddhu, S; Brosch, R; Brunelli, S; Chakraborty, H; Dember, LM; Edmonston, DL; Isakova, T; Wolf, M; Young, A, 2021)
"Hyperphosphatemia is a persistent problem in individuals undergoing maintenance hemodialysis, which may contribute to vascular and bone complications."( Carrero, JJ; Handu, D; Rozga, MR; St-Jules, DE, 2020)
"Hyperphosphatemia is a primary cause of CKD-related VC."( Chen, W; Guo, C; Pan, H; Peng, D; Wang, P, 2021)
"Hyperphosphatemia is associated with cardiovascular morbidity and mortality in patients receiving maintenance dialysis."( Chertow, GM; Pergola, PE; Rosenbaum, DP; Yang, Y, 2021)
"Hyperphosphatemia is associated with subclinical atheromatosis in chronic kidney disease."( Hénaut, L; Massy, ZA, 2021)
"Hyperphosphatemia is a common complication in patients on maintenance hemodialysis."( Li, P; Lian, R; Yin, J; Zheng, J, 2021)
"Hyperphosphatemia is a common complication as chronic kidney disease (CKD) progresses and most patients undergoing dialysis are prescribed oral phosphate binder therapy to control serum phosphate concentrations."( Ketteler, M; Sprague, SM, 2021)
"As hyperphosphatemia is associated with numerous adverse outcomes, including increased cardiovascular mortality, reduction in phosphorus concentrations is a guideline-recommended, established clinical practice."( Jacobs, JW; Rosenbaum, D; Sprague, SM; Yee, J, 2021)
"Hyperphosphatemia is a common feature in patients with chronic kidney disease (CKD), especially in those with end-stage renal disease (ESRD)."( Barbuto, S; Cianciolo, G; Ciceri, P; Cozzolino, M; Galassi, A; Iacovella, F; La Manna, G, 2022)
"Hyperphosphatemia is a common complication in dialysis-dependent patients with chronic kidney disease."( Coyne, DW; Kalantar-Zadeh, K; Ramos, R; Sprague, SM; Vervloet, M, 2022)
"Hyperphosphatemia is an inevitable complication for patients undergoing dialysis, as is the resulting need for treatment with phosphate binders."( Ito, H; Ogata, H; Takeshima, A, 2022)
"Hyperphosphatemia is often due to impaired kidney function and linked to vascular disease, hypertension and left ventricular hypertrophy."( Haffner, D; Leifheit-Nestler, M; Richter, B; Vogt, I, 2022)
"Hyperphosphatemia is almost universal in well-nourished patients with ESKD treated with dialysis due to an imbalance between dietary intake and phosphate removal via residual kidney function and dialysis."( Czikk, D; Farfan-Ruiz, AC; Leidecker, J; McCormick, B; Ramsay, T; Wilson, K; Zimmerman, D, 2021)
"Hyperphosphatemia is common in patients on peritoneal dialysis (PD)."( Andrews, ES; Kendrick, J; Perez, L; Ramirez-Renteria, L; Reddin, R; Teitelbaum, I; Wilson, G; You, Z, 2022)
"Hyperphosphatemia is a risk factor for cardiovascular outcomes in patients with chronic kidney disease."( Emoto, M; Fukumoto, S; Imanishi, Y; Mori, K; Morioka, T; Nagata, Y; Nakatani, S; Okute, Y; Shimomura, N; Shoji, T; Tsujimoto, Y; Uedono, H, 2023)
"Hyperphosphatemia is a secondary disorder of chronic kidney disease that causes vascular calcifications and bone-mineral disorders."( Anand, A; Aoyagi, H, 2023)
"Hyperphosphatemia is a common complication in advanced chronic kidney disease and contributes to cardiovascular morbidity and mortality."( Calabrese, V; Calderone, M; Casuscelli, C; Cernaro, V; Gembillo, G; Lo Re, C; Longhitano, E; Santoro, D, 2023)
"Hyperphosphatemia is associated with cardiovascular morbidity and mortality in adults with chronic kidney disease (CKD)."( Ai, X; Chen, X; Dong, H; Feng, J; Huang, B; Huang, X; Li, J; Li, L; Li, X; Li, Y; Luo, H; Xiao, H; Xue, G; You, S; Zhang, Y, 2023)
"BACKGROUND Hyperphosphatemia is a complication of chronic renal failure (CRF) due to reduction in the glomerular filtration rate."( Chang, X; Li, M; Shang, S; Xu, W; Yu, M; Zhou, Q, 2023)

Context

ExcerptReference
"Hyperphosphatemia has been shown to be a direct stimulus to several cell types including vascular smooth muscle cells migrating to the neointima of atherosclerotic plaques."( Hruska, KA; Mathew, S, 2011)
"Hypoalbuminemia and hyperphosphatemia have been shown to be strong predictors of mortality in dialysis patients that might not be independent from each other."( Freistätter, O; Knoll, F; Kronenberg, F; Lamina, C; Lhotta, K; Lins, F; Neyer, U; Sturm, G; Zitt, E, 2011)
"Hyperphosphatemia has been identified in the past decade as a strong predictor of mortality in advanced chronic kidney disease (CKD)."( Hahn, K; Ketteler, M; Kuhlmann, MK; Mann, J; Ritz, E, 2012)
"Hyperphosphatemia has clinically been associated with total mortality and cardiovascular mortality in patients with chronic renal failure (CRF)."( Iijima, K, 2012)
"Hyperphosphatemia has been implicated in the development and treatment of various cancers."( Guiles, F; Han, J; Lai, Y; Lin, L; Myers, RE; Palazzo, JP; Xing, J; Yang, H; Ye, Z, 2013)
"Hypo- and hyperphosphatemia have each been associated with increased mortality in maintenance hemodialysis (MHD) patients."( Brunelli, SM; Jing, J; Kalantar-Zadeh, K; Kovesdy, CP; Lau, WL; Lertdumrongluk, P; Molnar, MZ; Moradi, H; Nissenson, AR; Park, J; Rhee, CM, 2013)
"Hyperphosphatemia has been associated with higher mortality risk in CKD 5 patients receiving dialysis."( Benedik, M; Bos, WJ; Cannata-Andía, JB; Carrero, JJ; Covic, A; Fernández-Martín, JL; Ferreira, A; Floege, J; Goldsmith, D; Gorriz, JL; Ketteler, M; Kramar, R; Locatelli, F; London, G; Martin, PY; Martínez-Camblor, P; Memmos, D; Nagy, J; Naves-Díaz, M; Pavlovic, D; Rutkowski, B; Sánchez, JE; Teplan, V; Tielemans, C; Verbeelen, D; Wüthrich, RP; Zoccali, C, 2013)
"Chronic hyperphosphatemia have an impact on prognosis because the risk of cardiovascular event increases."( Fukagawa, M; Hamano, N, 2016)
"Hyperphosphatemia has been associated with an increased risk of mortality in patients with end-stage renal disease."( Anderson, L; Coyne, DW; Ficociello, LH; Kossmann, RJ; Maddux, FW; Mullon, C; Ofsthun, NJ; Parameswaran, V; Sprague, SM; Vemula, S, 2017)
"Hyperphosphatemia has consistently been shown to be associated with dismal outcome in a wide variety of populations, particularly in chronic kidney disease (CKD)."( van Ballegooijen, AJ; Vervloet, MG, 2018)
"Hyperphosphatemia has been demonstrated to be associated with an increased incidence of infection."( Kuragano, T; Nakanishi, T; Nanami, M, 2020)
"Hyperphosphatemia has been reported to be associated with the severity of CAC."( Fujii, H; Hamano, T; Isaka, Y; Koiwa, F; Sakaguchi, Y; Tanaka, R; Tatsugami, F; Teramukai, S; Tomiyama, N; Tsujimoto, Y, 2021)
"In human patients, hyperphosphatemia has been implicated in an increase in morbidity and mortality."( Michigami, T; Razzaque, MS; Yamazaki, M, 2022)
"Hyperphosphatemia has been associated with vascular wall stiffness that may alter blood flow and weakenvessels in the brain."( Abdelhady, HG; Acquaviva, J; Razzaque, MS, 2022)
"Hyperphosphatemia has emerged as an independent risk factor for cardiovascular disease (CVD) and excess mortality in chronic kidney disease (CKD)."( Gupta, A; Kapoor, V; Sachan, T; Saxena, A, 2022)

Actions

ExcerptReference
"Hyperphosphatemia affects most patients with end-stage renal disease (ESRD) and is associated with morbidity and mortality."( Dooley, JW; Hack, M; Rappaport, SH; Shah, T; Vineyard, T, 2023)

Treatment

ExcerptReference
"Sevelamer appears useful for the treatment of hyperphosphatemia in these patients."( Dobashi, Y; Hirawa, N; Iwatsubo, K; Iwatsubo, M; Kawaguchi, Y; Kokuho, T; Nakazawa, A; Ohnishi, T; Takeda, H; Tamura, K; Toya, Y; Umemura, S; Yasuda, G, 2007)
"Lanthanum (La) carbonate is a new treatment for hyperphosphatemia."( Auchère, D; Beaune, P; Benchitrit, J; Drüeke, TB; Flinois, JP; Joki, N; Lacour, B; Nikolov, IG; Patey, N; Vicca, S; Ziol, M, 2010)
"Phosphorus binders are used to treat hyperphosphatemia in maintenance dialysis patients, in whom the use of these medications has been associated with lower mortality in some observational studies."( Kalantar-Zadeh, K; Kovesdy, CP; Kuchmak, O; Lu, JL, 2010)
"In Canada, first-line treatment of hyperphosphatemia consists primarily of calcium carbonate (CC)."( Keith, MS; Lok, CE; Morton, AR; Soroka, SD; Tolley, K; Vegter, S, 2012)
"Phosphate binders are used in the treatment of hyperphosphatemia in peritoneal dialysis (PD) patients."( Eriguchi, M; Kitazono, T; Nakano, T; Tanaka, S; Taniguchi, M; Tsuruya, K; Yamada, S; Yoshida, H, 2012)
"In the treatment of hyperphosphatemia in dialysis patients, LC is well tolerated and more effective than placebo during short-term trials."( Di, B; Gao, X; Huang, W; Liu, J; Tang, Y; Zhang, F, 2014)
"Unfortunately, the treatment of hyperphosphatemia is far from being satisfactory."( Del Vecchio, L; Locatelli, F, 2014)
"Renal insufficiency improved with treatment."( Aeberhard, N; Rodondi, N; Roten-Joss, C; Schild, C; Tänzler, K, 2014)
"Sevelamer appears to be an effective treatment for hyperphosphatemia associated with tumour lysis syndrome."( Prasada, H, 2015)
"Unfortunately, the treatment of hyperphosphatemia is still far from resolved."( Del Vecchio, L; Locatelli, F, 2017)
"Phosphate binders are used to treat hyperphosphatemia among patients with chronic kidney disease (CKD)."( Garg, AX; Habbous, S; Martin, J; Przech, S; Sarma, S, 2018)
"The prevention and the treatment of hyperphosphatemia is today far to be satisfactory."( Carfagna, F; Del Vecchio, L; Locatelli, F; Pontoriero, G, 2018)
"Iron-based Pi-binders are used to treat hyperphosphatemia in CKD patients."( Block, GA; Bulfamante, G; Ciceri, P; Cozzolino, M; Falleni, M; Martinelli, C; Messa, P; Tosi, D, 2019)
"Lanthanum carbonate is used for treatment of hyperphosphatemia mostly in patients with chronic renal failure."( Iwamuro, M; Okada, H; Tanaka, T; Urata, H, 2020)
"Phosphate binders are most used to treat hyperphosphatemia and it is significant to develop its alternatives with high specific and low cost in the clinic."( Cha, R; He, C; Liu, Q; Mu, G; Ren, H; Wang, J; Wang, M; Xie, Q; Zhang, Q, 2021)
"Phosphate binders are used to treat hyperphosphatemia."( Akizawa, T; Fukagawa, M; Ikejiri, K; Kanda, H; Shigematsu, T; Une, Y, 2021)
"LC might be an alternative treatment for hyperphosphatemia in patients with CKD considering its comprehensive curative effect."( Liu, A; Xu, G; Zhao, L, 2021)
"LC-based treatment for hyperphosphatemia did not delay CAC for 2 years compared with CC-based treatment in hemodialysis patients with at least one risk factor for vascular calcification."( Akizawa, T; Fukagawa, M; Hirakata, H; Kagimura, T; Ogata, H, 2022)
"Phosphate binders are the main treatment for hyperphosphatemia in patients with chronic kidney disease, and iron-based phosphate binders have been used with increasing frequency in recent years."( Inaguma, D; Noma, H; Onishi, Y; Sasaki, S; Tanaka, A; Wang, J, 2023)

Research

Studies (1,099)

TimeframeStudies, This Condition (%)All Conditions %
pre-19907 (0.64)23.3326
1990's1 (0.09)12.5806
2000's178 (16.20)18.1394
2010's697 (63.42)28.8240
2020's216 (19.65)9.53
DrugIndicatedRelationship StrengthStudiesTrials
2,3-diphosphoglycerate0low10
gamma-aminobutyric acid0low10
adenine0low100
citric acid, anhydrous0medium41
chlorine0low10
salicylic acid0low10
lactic acid0low10
hydrogen carbonate0medium92
dalteparin0low10
hydrogen0low10
phytic acid0low10
melatonin0low10
niacin0medium122
phosphoric acid0low10
diphosphoric acid0low10
thiosulfates0low60
uric acid0medium73
urea0medium61
acetazolamide0low70
alendronate0low20
beta-glycerophosphoric acid0low20
4-cresol0medium11
deferoxamine0medium11
valproic acid0low10
fenfluramine0low10
fluconazole0low10
foscarnet0low50
furosemide0low20
gabapentin0low10
avapro0medium11
losartan0low10
activins0low10
niceritrol0low10
omeprazole0low10
pantoprazole0medium22
phloretin0low10
propranolol0low10
risedronic acid0low10
prednisolone0low10
spironolactone0low30
aldosterone0low40
prednisone0low10
lysine0low10
sucrose0medium3612
lactose0low10
ornithine0low10
tryptophan0low10
arginine0low10
epichlorohydrin0medium11
pyrroles0medium11
thiophenes0medium11
homoarginine0low10
thiazoles0low10
calcium gluconate0low30
fluorobenzenes0low10
magnesium carbonate0medium83
ethylnitrosourea0low10
calcium citrate0medium11
deoxycytidine0medium11
durapatite0low30
s,n,n'-tripropylthiocarbamate0medium11
carbonates0medium41
floxacillin0low10
lanthanum0medium16039
molybdenum0low20
technetium0low10
titanium0low10
cerium0low10
gadolinium0low10
magnesium sulfate0low10
phosphoric acid, trisodium salt0low280
sodium pyrophosphate0low10
tricalcium phosphate0medium213
sodium thiosulfate0low60
molybdate ion0low20
titanium dioxide0low10
fluorides0low10
phenyl acetate0medium3311
cetylpyridinium chloride anhydrous0low10
transferrin0medium63
gemcitabine0medium11
lamivudine0low10
ferric citrate0medium3611
vanadates0low10
potassium phosphate0low10
efavirenz0low10
aluminum phosphate0medium11
lanthanum chloride0low10
mci-1960medium106
triazoles0low10
zoledronic acid0low10
ceric oxide0low10
rosiglitazone0low10
nsc-1727550low10
fibrinogen0medium11
technetium tc 99m hydroxymethylene diphosphonate0low10
febuxostat0low10
lanthanum hydroxide0low20
cinacalcet0medium223
nps-5680low10
thiophosphoric acid0low10
lanthanum carbonate0medium14238
glycogen0low10
indican0medium22
tretinoin0low10
tenofovir0low10
sodium bicarbonate0low20
pyrophosphate0low40
u 01260low10
osteoprotegerin0low10
icodextrin0low10
4-cresol sulfate0medium11
bilirubin0low10
calcitriol0medium523
vitamin k semiquinone radical0low20
vitamin d 20medium133
cholecalciferol0low50
amphotericin b0low100
paricalcitol0medium112
acitretin0low10
sirolimus0low10
lead0low10
aluminum0medium41
ramipril0medium11
phosphorus0medium25066
cinanserin0low10
magnesium citrate0medium21
oxalates0low20
trk 8200low10
technetium tc 99m pyrophosphate0low10
gadolinium dtpa0low10
morphinans0low10
mk-05240medium11
azd 62440low10
palytoxin0low10
vx 7650low10
losartan potassium0low50
acid phosphatase0medium21
ferrous citrate0low10
cellulose0low20
endothelin-10low10
phosphatidylcholines0low10
chitosan0medium94
mersalyl0low10
egg white0low10
cardiovascular agents0low20
bixalomer0medium144
abt-1990low10
3-(2,6-dichloro-3,5-dimethoxyphenyl)-1-(6-(4-(4-ethylpiperazin-1-yl)-phenylamino)pyrimidin-4-yl)-1-methylurea0medium32
ascorbic acid0medium21
warfarin0low10
transforming growth factor beta0low10
borogluconate0low10
benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone0low10
ferric oxide, saccharated0medium3812
technetium tc 99m medronate0low10
cyclic gmp0low10
3-methyladenine0low10
allopurinol0low80
cholestyramine resin0low10
phosphorus radioisotopes0low10
leptin0low10

Protein Targets (1,547)

ProteinPotency MeasurementsInhibition MeasurementsActivation MeasurementsDrugs
PPM1D protein6006
cytochrome P450 family 3 subfamily A polypeptide 4240024
EWS/FLI fusion protein180018
G150015
cytochrome P450 2D68008
Interferon beta190019
HLA class I histocompatibility antigen, B alpha chain 150015
Fibroblast growth factor receptor 10123
Fibroblast growth factor receptor 20112
Fibroblast growth factor receptor 40112
Fibroblast growth factor receptor 30112
Fibroblast growth factor receptor 40101
Inositol hexakisphosphate kinase 1150015
Smoothened homolog0101
cytochrome P450 2C9, partial150015
Chain A, DNA-3-methyladenine glycosylase I0011
Chain A, DNA-3-METHYLADENINE GLYCOSYLASE I0011
Chain A, Dna-3-methyladenine Glycosylase I0011
interleukin 86006
RAR-related orphan receptor gamma200020
TDP1 protein250025
AR protein270027
progesterone receptor130013
retinoic acid nuclear receptor alpha variant 1310031
retinoid X nuclear receptor alpha140014
estrogen nuclear receptor alpha410041
aryl hydrocarbon receptor140014
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a190019
thyroid stimulating hormone receptor6006
thyroid hormone receptor beta isoform 2210021
nuclear factor erythroid 2-related factor 2 isoform 1260026
Sulfotransferase 1A1 0001
Acetylcholinesterase0404
Nuclear receptor ROR-gamma6118
Apoptosis regulator Bcl-20224
Spike glycoprotein8019
Bcl-2-like protein 10202
Induced myeloid leukemia cell differentiation protein Mcl-10202
Aspartyl/asparaginyl beta-hydroxylase0101
Bcl-2-related protein A10101
Bcl-2-like protein 20101
Bcl2-associated agonist of cell death 0101
Chain A, TYROSYL-DNA PHOSPHODIESTERASE100010
Chain A, CARBONIC ANHYDRASE II0011
Chain A, CARBONIC ANHYDRASE II0011
Chain A, CARBONIC ANHYDRASE II0011
Chain A, Carbonic Anhydrase Ii0011
Chain A, Carbonic Anhydrase Ii0011
Chain A, Beta-lactamase6006
Chain A, Endochitinase0101
Chain A, Endochitinase0101
Chain A, Endochitinase0101
Chain A, Class Iii Chitinase Chia10101
Chain A, Carbonic anhydrase 130101
Chain A, Carbonic anhydrase II0101
Chain A, Carbonic anhydrase 20101
Chain A, Carbonic anhydrase 20101
Chain A, Carbonic anhydrase 20101
Chain A, Carbonic anhydrase 20101
Chain A, Carbonic anhydrase 20101
Chain A, Carbonic anhydrase 20101
Chain A, Carbonic anhydrase 20101
Chain A, Carbonic anhydrase 20101
Chain A, Carbonic anhydrase 20101
Chain A, Carbonic anhydrase0101
Chain B, Carbonic anhydrase0101
Chain A, Carbonic anhydrase 20101
Carbonic anhydrase 0001
Carbonic anhydrase 0303
thioredoxin reductase110011
GALC protein1001
GLI family zinc finger 3220022
nuclear receptor subfamily 1, group I, member 3190019
glucocorticoid receptor [Homo sapiens]300030
estrogen-related nuclear receptor alpha250025
Carbonic anhydrase 0101
Carbonic anhydrase 0101
arylsulfatase A5005
Carbonic anhydrase0101
euchromatic histone-lysine N-methyltransferase 2220022
Bloom syndrome protein isoform 18008
thyroid hormone receptor beta isoform a140014
geminin220022
peripheral myelin protein 22100010
survival motor neuron protein isoform d100010
muscleblind-like protein 1 isoform 11001
Gamma-aminobutyric acid receptor subunit pi104115
ATP-binding cassette sub-family C member 3021021
Multidrug resistance-associated protein 4021022
Carbonic anhydrase0101
Solute carrier family 22 member 60303
Carbonic anhydrase 1206112
Prolyl endopeptidase0101
Carbonic anhydrase-related protein 110102
Bile salt export pump030030
Glycogen phosphorylase, muscle form0101
Renin0202
Carbonic anhydrase 1016124
Carbonic anhydrase 2019226
Carbonic anhydrase 20202
Cytochrome P450 1A20416
Carbonic anhydrase 30519
Cathepsin B0101
Cytochrome P450 3A409213
Steryl-sulfatase0101
5-hydroxytryptamine receptor 2C0303
Polyunsaturated fatty acid 5-lipoxygenase0101
Cytochrome P450 2C80202
Cytochrome P450 2D60617
Cytochrome P450 2A60202
Cytochrome P450 2C9 013317
5-hydroxytryptamine receptor 2A0303
Androgen receptor0506
Gamma-aminobutyric acid receptor subunit beta-1104115
Translocator protein0101
Gamma-aminobutyric acid receptor subunit delta104115
Gamma-aminobutyric acid receptor subunit gamma-2104216
Gamma-aminobutyric acid receptor subunit alpha-5104115
Gamma-aminobutyric acid receptor subunit alpha-3104115
Cannabinoid receptor 10101
Arachidonate 5-lipoxygenase-activating protein0101
Cytochrome P450 2B60102
Carbonic anhydrase 4013117
Carbonic anhydrase 60519
Gamma-aminobutyric acid receptor subunit gamma-1104115
Gamma-aminobutyric acid receptor subunit alpha-2104115
Carbonic anhydrase 5A, mitochondrial0101
Adenosine receptor A10101
Serum paraoxonase/arylesterase 10202
Dipeptidyl peptidase 40001
Gamma-aminobutyric acid receptor subunit alpha-4104115
Gamma-aminobutyric acid receptor subunit gamma-3104115
Endochitinase0101
Gamma-aminobutyric acid receptor subunit alpha-6104115
Adenosine receptor A2a0202
5-hydroxytryptamine receptor 2B0303
Sodium-dependent serotonin transporter0213
Delta-type opioid receptor0101
Cytochrome P450 2C190719
Delta-type opioid receptor0101
Mu-type opioid receptor0404
Carbonic anhydrase 5A, mitochondrial08113
Carbonic anhydrase0708
Kappa-type opioid receptor0224
Carbonic anhydrase 706110
Carbonic anhydrase0101
D(1A) dopamine receptor0101
Corticosteroid 11-beta-dehydrogenase isozyme 10202
Carbonic anhydrase0102
D(2) dopamine receptor0101
Gamma-aminobutyric acid receptor subunit alpha-1104216
Gamma-aminobutyric acid receptor subunit beta-3104115
Gamma-aminobutyric acid receptor subunit beta-2104216
Cholinesterase0101
Carbonic anhydrase 0101
Mu-type opioid receptor0314
Fatty-acid amide hydrolase 10202
Beta-carbonic anhydrase 10202
Carbonic anhydrase 20101
Glutamate receptor ionotropic, NMDA 2B0102
Squalene synthase0202
Neuronal acetylcholine receptor subunit alpha-70101
Carbonic anhydrase 9010217
Carbonic anhydrase0202
Carbonic anhydrase, alpha family 0101
Carbonic anhydrase 0102
Carbonic anhydrase 30101
Carbonic anhydrase0103
Carbonic anhydrase0103
Carbonic anhydrase 0101
Sigma intracellular receptor 20101
Delta carbonic anhydrase0101
Sigma non-opioid intracellular receptor 10202
Renin0101
Carbonic anhydrase 0102
Endochitinase A10101
Multidrug resistance-associated protein 10101
Carbonic anhydrase 130315
GABA theta subunit104115
Canalicular multispecific organic anion transporter 1017017
Carbonic anhydrase 40202
Carbonic anhydrase 150709
Acidic mammalian chitinase0101
Carbonic anhydrase 130508
Carbonic anhydrase 70101
Gamma-aminobutyric acid receptor subunit epsilon104115
Carbonic anhydrase 0303
Carbonic anhydrase 1406112
Carbonic anhydrase 0101
Carbonic anhydrase 2, isoform A 0101
Carbonic anhydrase 5B, mitochondrial07112
Chain A, JmjC domain-containing histone demethylation protein 3A5005
Luciferase9009
USP1 protein, partial140014
Microtubule-associated protein tau130013
aldehyde dehydrogenase 1 family, member A1180018
peroxisome proliferator activated receptor gamma180018
vitamin D3 receptor isoform VDRA110011
flap endonuclease 14004
serine/threonine-protein kinase PLK13003
eyes absent homolog 2 isoform a2002
DNA polymerase eta isoform 12002
histone acetyltransferase KAT2A isoform 1110011
Bile salt export pump0707
Rap guanine nucleotide exchange factor 36006
Cellular tumor antigen p53210021
Rap guanine nucleotide exchange factor 41001
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE7007
Chain A, MTA/SAH nucleosidase0101
Chain A, Ribosome-inactivating protein alpha-trichosanthin0011
Chain A, Ricin A chain0011
Chain A, Ribosome-inactivating protein 30011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
pregnane X nuclear receptor190019
nuclear factor erythroid 2-related factor 2 isoform 27007
heat shock protein beta-17007
importin subunit beta-1 isoform 11001
snurportin-11001
tumor susceptibility gene 101 protein1001
GTP-binding nuclear protein Ran isoform 11001
lamin isoform A-delta10190019
Voltage-dependent calcium channel gamma-2 subunit100010
Cyclin-dependent kinase 10123
Heat shock protein HSP 90-beta0101
Glutamate receptor 2100010
Xanthine dehydrogenase/oxidase0607
TAR DNA-binding protein 434004
Protein mono-ADP-ribosyltransferase PARP150202
Leucine-rich repeat serine/threonine-protein kinase 20213
ATPase family AAA domain-containing protein 5100010
Ataxin-2110011
Sex hormone-binding globulin0011
Corticosteroid-binding globulin0202
Mineralocorticoid receptor 0539
Mineralocorticoid receptor0101
Solute carrier organic anion transporter family member 1A10001
Guanine nucleotide-binding protein G2002
Chain A, farnesyl pyrophosphate synthase0101
Geranylgeranyl pyrophosphate synthase0506
Farnesyl pyrophosphate synthase0808
Hypoxanthine-guanine phosphoribosyltransferase0101
Farnesyl pyrophosphate synthase 0505
Farnesyl pyrophosphate synthase 0303
thyroid stimulating hormone receptor6006
estrogen receptor 2 (ER beta)130013
IDH15005
transcriptional regulator ERG isoform 33003
ras-related protein Rab-9A2002
Polyphenol oxidase 20405
Hypoxanthine-guanine phosphoribosyltransferase0001
Xanthine dehydrogenase/oxidase [Includes: Xanthine dehydrogenase 0202
Adenosine receptor A2a0123
Nuclear receptor ROR-gamma0202
Xanthine dehydrogenase/oxidase0517
Purine nucleoside phosphorylase0011
Shiga toxin subunit A0101
Histamine H3 receptor0202
Chain A, HADH2 protein9009
Chain B, HADH2 protein9009
Chain A, Cruzipain7007
phosphopantetheinyl transferase100010
GLS protein5005
farnesoid X nuclear receptor150015
peroxisome proliferator-activated receptor delta110011
vitamin D (1,25- dihydroxyvitamin D3) receptor140014
tumor necrosis factor1001
Potassium voltage-gated channel subfamily H member 20404
Aurora kinase B0123
Broad substrate specificity ATP-binding cassette transporter ABCG20808
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN0022
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN0022
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN0022
NFKB1 protein, partial1001
alpha-galactosidase1001
cytochrome P450 2C19 precursor3003
chromobox protein homolog 19009
DNA polymerase iota isoform a (long)7007
muscarinic acetylcholine receptor M13003
lethal factor (plasmid)5005
Nitric oxide synthase, endothelial0002
Nitric oxide synthase, brain0001
Nitric oxide synthase, brain 0001
Nitric oxide synthase, inducible0001
Nitric oxide synthase, inducible0013
Cationic amino acid transporter 30202
ATP-dependent phosphofructokinase6006
Chain A, Hyaluronidase, phage associated0101
acetylcholinesterase9009
thioredoxin glutathione reductase8008
lethal(3)malignant brain tumor-like protein 1 isoform I1001
Pancreatic alpha-amylase0202
Albumin0101
Urease0101
Prolyl 4-hydroxylase subunit alpha-10001
Tyrosinase0101
Alpha-2B adrenergic receptor0023
Hyaluronate lyase0101
Prolyl hydroxylase EGLN20001
Egl nine homolog 10001
Prolyl hydroxylase EGLN30001
Hypoxia-inducible factor 1-alpha inhibitor0001
Solute carrier family 23 member 10101
lysosomal alpha-glucosidase preproprotein3003
mitogen-activated protein kinase 15005
cytochrome P450 3A4 isoform 1100010
Neuronal acetylcholine receptor subunit alpha-42002
Neuronal acetylcholine receptor subunit beta-22002
Thromboxane A2 receptor 0215
Endothelin-1 receptor0314
Type-1B angiotensin II receptor0505
Type-1 angiotensin II receptor05210
Type-2 angiotensin II receptor0202
Sodium/bile acid cotransporter0505
Multidrug and toxin extrusion protein 10606
Leukotriene B4 receptor 20011
Leukotriene C4 synthase0011
Bone morphogenetic protein receptor type-1B0022
Membrane-associated progesterone receptor component 10011
Cell division cycle 7-related protein kinase0022
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform0011
Serine/threonine-protein kinase PLK40022
Serine/threonine-protein kinase 250011
ATP-dependent RNA helicase DDX3X0022
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta0011
Pyridoxal kinase0022
Citron Rho-interacting kinase0022
Serine/threonine-protein kinase RIO30011
Dual specificity mitogen-activated protein kinase kinase 70011
Serine/threonine-protein kinase Chk10022
Inhibitor of nuclear factor kappa-B kinase subunit beta0012
Peripheral plasma membrane protein CASK0011
Aurora kinase A0022
Cyclin-G-associated kinase0022
Serine/threonine-protein kinase DCLK10011
Inhibitor of nuclear factor kappa-B kinase subunit alpha0011
Muscle, skeletal receptor tyrosine-protein kinase0011
Ephrin type-B receptor 60022
Peroxisomal acyl-coenzyme A oxidase 30022
Mitogen-activated protein kinase 130022
3-phosphoinositide-dependent protein kinase 10011
Mitogen-activated protein kinase kinase kinase 130011
Death-associated protein kinase 30011
Mitogen-activated protein kinase kinase kinase 70011
Receptor-interacting serine/threonine-protein kinase 20022
Mitotic checkpoint serine/threonine-protein kinase BUB10022
NUAK family SNF1-like kinase 10011
Dynamin-like 120 kDa protein, mitochondrial0022
Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma0011
Tyrosine-protein kinase JAK20022
Eukaryotic translation initiation factor 5B0022
Rho-associated protein kinase 20022
Serine/threonine-protein kinase ULK10022
Serine/threonine-protein kinase/endoribonuclease IRE10022
Ribosomal protein S6 kinase alpha-50022
U5 small nuclear ribonucleoprotein 200 kDa helicase0022
Ribosomal protein S6 kinase alpha-40022
Serine/threonine-protein kinase 160022
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma0011
Serine/threonine-protein kinase PAK 30011
Cyclin-dependent kinase-like 50022
Serine/threonine-protein kinase 17B0011
Serine/threonine-protein kinase 100022
Serine/threonine-protein kinase D30022
Cyclin-dependent kinase 140011
Structural maintenance of chromosomes protein 20022
Mitogen-activated protein kinase kinase kinase 60022
Serine/threonine-protein kinase OSR10011
Mitogen-activated protein kinase kinase kinase kinase 40022
Serine/threonine-protein kinase LATS10022
Serine/threonine-protein kinase PAK 40022
Serine/threonine-protein kinase Chk20011
Tyrosine-protein kinase ABL10022
Epidermal growth factor receptor0123
RAF proto-oncogene serine/threonine-protein kinase0112
Receptor tyrosine-protein kinase erbB-20011
High affinity nerve growth factor receptor0022
Guanine nucleotide-binding protein G(i) subunit alpha-20011
ADP/ATP translocase 20022
Protein kinase C beta type0022
Insulin receptor0022
Tyrosine-protein kinase Lck0033
Tyrosine-protein kinase Fyn0022
Glycogen phosphorylase, liver form0022
Tyrosine-protein kinase Fes/Fps0022
Macrophage colony-stimulating factor 1 receptor0011
Adenine phosphoribosyltransferase0022
Tyrosine-protein kinase Yes0022
Tyrosine-protein kinase Lyn0022
Proto-oncogene tyrosine-protein kinase receptor Ret0022
Insulin-like growth factor 1 receptor0022
Signal recognition particle receptor subunit alpha0022
Cytochrome c1, heme protein, mitochondrial0022
Hepatocyte growth factor receptor0022
Tyrosine-protein kinase HCK0022
Proto-oncogene tyrosine-protein kinase ROS0011
Platelet-derived growth factor receptor beta0022
Tyrosine-protein kinase Fgr0022
Wee1-like protein kinase 20011
Uncharacterized serine/threonine-protein kinase SBK30011
Serine/threonine-protein kinase A-Raf0022
Mast/stem cell growth factor receptor Kit0011
Glycogen phosphorylase, brain form0022
Breakpoint cluster region protein0022
Serine/threonine-protein kinase pim-10022
DNA topoisomerase 2-alpha0022
Cyclin-dependent kinase 40022
ADP/ATP translocase 30022
Inosine-5'-monophosphate dehydrogenase 20022
Proto-oncogene tyrosine-protein kinase Src0224
cAMP-dependent protein kinase type II-alpha regulatory subunit0022
Insulin receptor-related protein0011
Serine/threonine-protein kinase B-raf0123
Phosphorylase b kinase gamma catalytic chain, liver/testis isoform0022
Ribosyldihydronicotinamide dehydrogenase [quinone]0224
Platelet-derived growth factor receptor alpha0011
Tyrosine-protein kinase Fer0022
Protein kinase C alpha type0022
cAMP-dependent protein kinase catalytic subunit alpha0022
Vascular endothelial growth factor receptor 1 0011
General transcription and DNA repair factor IIH helicase subunit XPD0022
Interferon-induced, double-stranded RNA-activated protein kinase0011
Casein kinase II subunit alpha'0022
Ras-related protein Rab-6A0022
Serine/threonine-protein kinase MAK0011
Cyclin-dependent kinase 11B0011
Ephrin type-A receptor 10022
Receptor tyrosine-protein kinase erbB-30011
Multifunctional protein ADE20022
cAMP-dependent protein kinase catalytic subunit beta0022
Ferrochelatase, mitochondrial0022
Ribosomal protein S6 kinase beta-10022
Tyrosine-protein kinase JAK10022
Protein kinase C eta type0011
Cyclin-dependent kinase 20022
Beta-adrenergic receptor kinase 10022
Probable ATP-dependent RNA helicase DDX60022
Activin receptor type-2A0011
Mitogen-activated protein kinase 3 0033
MAP/microtubule affinity-regulating kinase 30022
Deoxycytidine kinase0024
Mitogen-activated protein kinase 10134
Ephrin type-A receptor 20022
Ephrin type-A receptor 30011
Ephrin type-A receptor 80011
Ephrin type-B receptor 20022
Leukocyte tyrosine kinase receptor0011
Non-receptor tyrosine-protein kinase TYK20022
UMP-CMP kinase 0022
Phosphatidylethanolamine-binding protein 10022
Wee1-like protein kinase0022
Heme oxygenase 20022
Tyrosine-protein kinase receptor UFO0011
Mitogen-activated protein kinase 40011
S-adenosylmethionine synthase isoform type-20022
DnaJ homolog subfamily A member 10022
RAC-alpha serine/threonine-protein kinase0123
RAC-beta serine/threonine-protein kinase0022
G protein-coupled receptor kinase 40011
Dual specificity protein kinase TTK0022
DNA replication licensing factor MCM40022
Prostaglandin G/H synthase 20213
Myosin-100022
Tyrosine-protein kinase receptor Tie-10011
Vascular endothelial growth factor receptor 30011
Vascular endothelial growth factor receptor 20011
Dual specificity mitogen-activated protein kinase kinase 20224
Receptor-type tyrosine-protein kinase FLT30022
Bone morphogenetic protein receptor type-1A0022
Activin receptor type-1B0022
TGF-beta receptor type-10022
Serine/threonine-protein kinase receptor R30022
TGF-beta receptor type-20022
Electron transfer flavoprotein subunit beta0022
Tyrosine-protein kinase CSK0022
Glycine--tRNA ligase0022
Protein kinase C iota type0022
Exosome RNA helicase MTR40022
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform0011
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform0011
Serine/threonine-protein kinase mTOR0123
Megakaryocyte-associated tyrosine-protein kinase0011
Tyrosine-protein kinase Tec0022
Tyrosine-protein kinase TXK0011
Tyrosine-protein kinase ABL20022
Tyrosine-protein kinase FRK0022
Tyrosine-protein kinase ZAP-700011
Tyrosine-protein kinase SYK0022
26S proteasome regulatory subunit 6B0123
Mitogen-activated protein kinase 80022
Mitogen-activated protein kinase 90022
Dual specificity mitogen-activated protein kinase kinase 40011
Dual specificity mitogen-activated protein kinase kinase 30022
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha0022
Casein kinase I isoform alpha0022
Casein kinase I isoform delta0022
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform 0011
MAP kinase-activated protein kinase 20022
Cyclin-dependent kinase 80011
Elongation factor Tu, mitochondrial0022
Choline-phosphate cytidylyltransferase A0022
Cysteine--tRNA ligase, cytoplasmic0022
Casein kinase I isoform epsilon0022
Very long-chain specific acyl-CoA dehydrogenase, mitochondrial0022
Dual specificity protein kinase CLK10022
Dual specificity protein kinase CLK20022
Dual specificity protein kinase CLK30022
Glycogen synthase kinase-3 alpha0022
Glycogen synthase kinase-3 beta0022
Cyclin-dependent kinase 70022
Cyclin-dependent kinase 90022
Ras-related protein Rab-27A0022
Tyrosine-protein kinase Blk0011
Interleukin-1 receptor-associated kinase 10022
Ribosomal protein S6 kinase alpha-30022
Cytoplasmic tyrosine-protein kinase BMX0011
cAMP-dependent protein kinase catalytic subunit PRKX0011
Serine/threonine-protein kinase Nek20022
Serine/threonine-protein kinase Nek30022
Serine/threonine-protein kinase Nek40011
Tyrosine-protein kinase JAK30011
Dual specificity mitogen-activated protein kinase kinase 60022
Serine/threonine-protein kinase PLK10022
Death-associated protein kinase 10011
LIM domain kinase 10022
LIM domain kinase 20022
Mitogen-activated protein kinase 120022
Mitogen-activated protein kinase 100022
Tyrosine--tRNA ligase, cytoplasmic0022
5'-AMP-activated protein kinase subunit gamma-10023
5'-AMP-activated protein kinase catalytic subunit alpha-20012
Ephrin type-B receptor 30022
Ephrin type-A receptor 50022
Ephrin type-B receptor 40022
Ephrin type-B receptor 10011
Ephrin type-A receptor 40022
Adenylate kinase 2, mitochondrial0023
Adenosine kinase0022
Hormonally up-regulated neu tumor-associated kinase0011
Serine/threonine-protein kinase SIK10011
Receptor-interacting serine/threonine-protein kinase 40011
Ras-related protein Rab-100022
Cell division control protein 2 homolog0011
Actin-related protein 30022
Actin-related protein 20022
Calcium-dependent protein kinase 10011
GTP-binding nuclear protein Ran0022
Casein kinase II subunit alpha0011
Phosphatidylinositol 5-phosphate 4-kinase type-2 beta0011
SRSF protein kinase 20011
Casein kinase I isoform gamma-20022
Mitogen-activated protein kinase kinase kinase 90011
Serine/threonine-protein kinase PknB0011
Cyclin-dependent kinase 30011
Cyclin-dependent kinase-like 10011
Cyclin-dependent kinase 60022
Cyclin-dependent-like kinase 5 0022
Cyclin-dependent kinase 160022
Cyclin-dependent kinase 170022
ATP-dependent 6-phosphofructokinase, platelet type0022
Protein kinase C epsilon type0011
Dual specificity mitogen-activated protein kinase kinase 10224
Angiopoietin-1 receptor0011
Mitogen-activated protein kinase kinase kinase 100011
DNA topoisomerase 2-beta0022
Protein kinase C theta type0022
Activin receptor type-10022
Macrophage-stimulating protein receptor0022
Focal adhesion kinase 10022
Protein kinase C zeta type0022
Protein kinase C delta type0022
Tyrosine-protein kinase BTK0022
Tyrosine-protein kinase receptor TYRO30011
Cyclin-dependent kinase 180022
Activated CDC42 kinase 10022
Epithelial discoidin domain-containing receptor 10022
Tyrosine-protein kinase ITK/TSK0011
Myotonin-protein kinase0011
Mitogen-activated protein kinase kinase kinase kinase 20022
Mitogen-activated protein kinase kinase kinase 120011
Tyrosine-protein kinase Mer0022
Serine/threonine-protein kinase 40022
5'-AMP-activated protein kinase catalytic subunit alpha-10023
Serine/threonine-protein kinase PAK 10011
Dual specificity mitogen-activated protein kinase kinase 50022
Mitogen-activated protein kinase 70022
Serine/threonine-protein kinase PAK 20022
Serine/threonine-protein kinase 30022
Mitogen-activated protein kinase kinase kinase 10022
cGMP-dependent protein kinase 20011
Integrin-linked protein kinase0022
Rho-associated protein kinase 10022
Non-receptor tyrosine-protein kinase TNK10022
Serine/threonine-protein kinase PRP4 homolog0011
Receptor-interacting serine/threonine-protein kinase 10011
Calcium/calmodulin-dependent protein kinase type II subunit beta0011
Calcium/calmodulin-dependent protein kinase type II subunit gamma0022
Calcium/calmodulin-dependent protein kinase type II subunit delta0022
Dual specificity tyrosine-phosphorylation-regulated kinase 1A0022
Activin receptor type-2B0022
Bone morphogenetic protein receptor type-20022
Protein-tyrosine kinase 60022
cGMP-dependent protein kinase 1 0022
Cyclin-dependent kinase 130022
Calcium/calmodulin-dependent protein kinase type 10011
Inhibitor of nuclear factor kappa-B kinase subunit epsilon0022
Protein-tyrosine kinase 2-beta0022
Maternal embryonic leucine zipper kinase0022
Structural maintenance of chromosomes protein 1A0022
Chromodomain-helicase-DNA-binding protein 40022
Peroxisomal acyl-coenzyme A oxidase 10022
Serine/threonine-protein kinase D10011
Serine/threonine-protein kinase 380011
Receptor tyrosine-protein kinase erbB-40011
Ribosomal protein S6 kinase alpha-20011
Ephrin type-A receptor 70011
Delta(24)-sterol reductase0022
Ribosomal protein S6 kinase alpha-10022
Dual specificity testis-specific protein kinase 10022
Myosin light chain kinase, smooth muscle0022
Mitogen-activated protein kinase 110033
Serine/threonine-protein kinase STK110022
Rhodopsin kinase GRK10011
NT-3 growth factor receptor0011
Serine/threonine-protein kinase N10022
Serine/threonine-protein kinase N20022
Mitogen-activated protein kinase 140134
Calcium/calmodulin-dependent protein kinase type IV0022
Mitogen-activated protein kinase kinase kinase 110022
BDNF/NT-3 growth factors receptor0011
Mitogen-activated protein kinase 60011
Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform0011
Discoidin domain-containing receptor 20022
AP2-associated protein kinase 10022
Myosin light chain kinase 30022
Serine/threonine-protein kinase SBK10011
Mitogen-activated protein kinase kinase kinase 190011
Putative heat shock protein HSP 90-beta 20022
Serine/threonine-protein kinase TNNI3K0011
Rab-like protein 30011
Serine/threonine-protein kinase MRCK alpha0022
Serine/threonine-protein kinase MRCK gamma0022
Acyl-CoA dehydrogenase family member 100022
Serine/threonine-protein kinase Nek50011
Serine/threonine-protein kinase N30022
Serine/threonine-protein kinase ULK30022
Dual serine/threonine and tyrosine protein kinase0011
Mitogen-activated protein kinase kinase kinase 150011
Uncharacterized protein FLJ452520022
Acyl-CoA dehydrogenase family member 110022
Serine/threonine-protein kinase/endoribonuclease IRE20022
Serine/threonine-protein kinase MARK20022
Serine/threonine-protein kinase TAO10022
STE20-related kinase adapter protein alpha0022
Myosin-140022
AarF domain-containing protein kinase 10022
Serine/threonine-protein kinase tousled-like 20011
Serine/threonine-protein kinase 32C0011
Serine/threonine-protein kinase pim-30011
ATP-dependent RNA helicase DDX420011
Serine/threonine-protein kinase VRK20011
Myosin light chain kinase family member 40011
Homeodomain-interacting protein kinase 10011
Calcium/calmodulin-dependent protein kinase type 1D0011
Mitogen-activated protein kinase kinase kinase kinase 30022
Cyclin-dependent kinase-like 30011
MAP kinase-activated protein kinase 50123
Serine/threonine-protein kinase BRSK20011
Serine/threonine-protein kinase NIM10011
Serine/threonine-protein kinase ULK20011
Misshapen-like kinase 10022
Serine/threonine-protein kinase DCLK20011
Calcium/calmodulin-dependent protein kinase kinase 10011
Casein kinase I isoform alpha-like0011
Homeodomain-interacting protein kinase 40011
Myosin-IIIa0011
Ankyrin repeat and protein kinase domain-containing protein 10011
Serine/threonine-protein kinase Nek110011
Atypical kinase COQ8A, mitochondrial0022
Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma0022
Mitogen-activated protein kinase 150022
Serine/threonine-protein kinase Nek90022
Serine/threonine-protein kinase BRSK10011
Serine/threonine-protein kinase 350011
Serine/threonine-protein kinase Nek70011
Rhodopsin kinase GRK70011
Serine/threonine-protein kinase 32A0011
Myosin-IIIb0011
ATP-dependent RNA helicase DDX10022
Dual specificity tyrosine-phosphorylation-regulated kinase 20011
Cyclin-dependent kinase-like 20011
Mitogen-activated protein kinase kinase kinase kinase 10022
Serine/threonine-protein kinase Sgk30011
Atypical kinase COQ8B, mitochondrial0011
MAP/microtubule affinity-regulating kinase 40022
Calcium/calmodulin-dependent protein kinase type 1G0022
Serine/threonine-protein kinase Nek10022
Cyclin-dependent kinase 150011
PAS domain-containing serine/threonine-protein kinase0022
Calcium/calmodulin-dependent protein kinase kinase 20022
EKC/KEOPS complex subunit TP53RK0022
Dual specificity testis-specific protein kinase 20022
SRSF protein kinase 10011
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase0022
Mitogen-activated protein kinase kinase kinase 50022
Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha0011
Mitogen-activated protein kinase kinase kinase 30022
Eukaryotic translation initiation factor 2-alpha kinase 10022
Serine/threonine-protein kinase RIO10011
MAP kinase-interacting serine/threonine-protein kinase 10011
Serine/threonine-protein kinase RIO20011
Cyclin-dependent kinase 190011
Transient receptor potential cation channel subfamily M member 60011
Testis-specific serine/threonine-protein kinase 10011
Serine/threonine-protein kinase 330011
Nucleolar GTP-binding protein 10022
Serine/threonine-protein kinase D20022
Serine/threonine-protein kinase DCLK30011
NUAK family SNF1-like kinase 20011
RNA cytidine acetyltransferase0022
Serine/threonine-protein kinase SIK20022
Myosin light chain kinase 2, skeletal/cardiac muscle0011
STE20-like serine/threonine-protein kinase 0022
Serine/threonine-protein kinase TAO30022
Homeodomain-interacting protein kinase 20011
Tyrosine-protein kinase Srms0011
Homeodomain-interacting protein kinase 30011
Serine/threonine-protein kinase PLK30011
dCTP pyrophosphatase 10022
Dual specificity protein kinase CLK40022
MAP kinase-interacting serine/threonine-protein kinase 20011
Serine/threonine-protein kinase Nek60011
Casein kinase I isoform gamma-10022
Serine/threonine-protein kinase PAK 60011
SNF-related serine/threonine-protein kinase0011
Serine/threonine-protein kinase LATS20011
Serine/threonine-protein kinase 360011
Phenylalanine--tRNA ligase beta subunit0022
Isoleucine--tRNA ligase, mitochondrial0022
BMP-2-inducible protein kinase0022
Obg-like ATPase 10022
Midasin0022
Interleukin-1 receptor-associated kinase 40022
Serine/threonine-protein kinase 32B0011
Mitogen-activated protein kinase kinase kinase 200022
Cyclin-dependent kinase 120022
Serine/threonine-protein kinase PLK20011
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 130011
Serine/threonine-protein kinase MARK10011
Serine/threonine-protein kinase pim-20011
Serine/threonine-protein kinase PAK 50011
Serine/threonine-protein kinase 260022
eIF-2-alpha kinase GCN20011
Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial0022
Serine/threonine-protein kinase NLK0022
Phosphatidylinositol 4-kinase beta0011
Serine/threonine-protein kinase 17A0011
STE20/SPS1-related proline-alanine-rich protein kinase0011
Ephrin type-A receptor 60011
5'-AMP-activated protein kinase subunit gamma-20023
Serine/threonine-protein kinase TBK10022
Septin-90022
Death-associated protein kinase 20011
Ribosomal protein S6 kinase alpha-60022
TRAF2 and NCK-interacting protein kinase0022
Serine/threonine-protein kinase tousled-like 10011
Serine/threonine-protein kinase TAO20022
Long-chain-fatty-acid--CoA ligase 50011
ALK tyrosine kinase receptor0011
SRSF protein kinase 30011
Serine/threonine-protein kinase ICK0022
Cyclin-dependent kinase 11A0011
Aurora kinase C0011
Calcium/calmodulin-dependent protein kinase type II subunit alpha0011
RAC-gamma serine/threonine-protein kinase0022
Serine/threonine-protein kinase 38-like0011
Microtubule-associated serine/threonine-protein kinase 10011
Serine/threonine-protein kinase SIK30022
Mitogen-activated protein kinase kinase kinase 20022
Thyroid hormone receptor-associated protein 30022
Dual specificity tyrosine-phosphorylation-regulated kinase 1B0022
Mitogen-activated protein kinase kinase kinase kinase 50022
Receptor-interacting serine/threonine-protein kinase 30022
Serine/threonine-protein kinase MRCK beta0022
Interleukin-1 receptor-associated kinase 30022
Serine/threonine-protein kinase 240022
Casein kinase I isoform gamma-30022
Mitogen-activated protein kinase kinase kinase 40022
Eyes absent homolog 20101
Chain A, Putative fructose-1,6-bisphosphate aldolase3003
Chain A, 2-oxoglutarate Oxygenase100010
DNA polymerase kappa isoform 15005
caspase-1 isoform alpha precursor1001
Caspase-71001
Inositol monophosphatase 13003
Solute carrier organic anion transporter family member 1B30405
Solute carrier organic anion transporter family member 1B10507
Chain H, Proteasome component PUP10101
Chain I, Proteasome component PUP30101
Chain K, Proteasome component PRE20101
Chain L, Proteasome component C50101
Chain K, Proteasome component PRE20101
Chain L, Proteasome component C50101
Proteasome subunit beta type-110101
Fumarate hydratase2002
caspase 7, apoptosis-related cysteine protease5005
polyprotein2002
caspase-35005
nuclear receptor subfamily 1, group I, member 23003
Histone H2A.x4004
Caspase-73003
caspase-33003
26S proteasome non-ATPase regulatory subunit 110101
26S proteasome non-ATPase regulatory subunit 120101
26S proteasome non-ATPase regulatory subunit 140101
Proteasome subunit alpha type-70101
Histone deacetylase 30505
26S proteasome non-ATPase regulatory subunit 30101
Prothrombin0101
Chymotrypsinogen A0303
Cathepsin B0101
Neutrophil elastase0101
Cathepsin G0202
Lysosomal protective protein0101
Chymotrypsinogen B0202
26S proteasome regulatory subunit 6A0101
Nuclear factor NF-kappa-B p105 subunit0202
Proteasome subunit beta type-10102
Chymase0101
Proteasome subunit alpha type-10101
Proteasome subunit alpha type-20101
Proteasome subunit alpha type-30101
Proteasome subunit alpha type-40101
Proteasome subunit beta type-80101
Proteasome subunit beta type-80101
Proteasome subunit beta type-90101
Proteasome subunit alpha type-50101
Proteasome subunit beta type-40101
Proteasome subunit beta type-60101
Proteasome subunit beta type-50203
26S proteasome regulatory subunit 70101
Lon protease homolog, mitochondrial0101
Proteasome subunit beta type-100101
26S proteasome non-ATPase regulatory subunit 80101
Proteasome subunit beta type-30101
Proteasome subunit beta type-20102
26S proteasome non-ATPase regulatory subunit 70101
26S proteasome non-ATPase regulatory subunit 40101
26S proteasome complex subunit SEM10101
Proteasome subunit alpha type-60101
26S proteasome regulatory subunit 40101
26S proteasome regulatory subunit 80101
26S proteasome regulatory subunit 10B0101
Nuclear factor NF-kappa-B p100 subunit 0202
Transcription factor p650202
26S proteasome non-ATPase regulatory subunit 20101
Histone deacetylase 10505
26S proteasome non-ATPase regulatory subunit 60101
Proteasomal ubiquitin receptor ADRM10101
ATP-dependent Clp protease proteolytic subunit0112
NACHT, LRR and PYD domains-containing protein 3 0101
Proteasome subunit alpha-type 80101
Histone deacetylase 20505
Proteasome subunit beta type-70101
26S proteasome non-ATPase regulatory subunit 10101
Histone deacetylase 80505
Histone deacetylase 60505
26S proteasome non-ATPase regulatory subunit 130101
Chain A, Vitamin D Nuclear Receptor0011
Chain A, Ferritin light chain8008
Vitamin D3 receptor0011
nuclear receptor ROR-gamma isoform 1100010
Vitamin D-binding protein0011
Androgen receptor0516
Vitamin D3 receptor0239
Vitamin D3 receptor0113
Retinoic acid receptor RXR-alpha0257
Vitamin D3 receptor0022
1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial0011
Vitamin D3 receptor0112
Transporter0101
Vitamin D3 receptor A0022
hypoxia-inducible factor 1 alpha subunit5005
SMAD family member 26006
SMAD family member 36006
67.9K protein6006
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)1001
activating transcription factor 67007
thyrotropin-releasing hormone receptor5005
v-jun sarcoma virus 17 oncogene homolog (avian)100010
Caspase-20011
15-lipoxygenase, partial2002
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 17007
60 kDa chaperonin0303
60 kDa heat shock protein, mitochondrial0303
Glycine receptor subunit alpha-10022
10 kDa heat shock protein, mitochondrial0303
Thiosulfate sulfurtransferase0303
60 kDa chaperonin 0303
10 kDa chaperonin 0303
Smad35005
PINK11001
Parkin2002
huntingtin isoform 22002
Extracellular calcium-sensing receptor0022
Angiotensin-converting enzyme 2 0112
regulator of G-protein signaling 48008
potassium voltage-gated channel subfamily H member 2 isoform d7007
histone deacetylase 9 isoform 32002
Replicase polyprotein 1ab0213
Replicase polyprotein 1ab0213
5-hydroxytryptamine receptor 1A0518
5-hydroxytryptamine receptor 2A0314
5-hydroxytryptamine receptor 2C0314
5-hydroxytryptamine receptor 1B0303
5-hydroxytryptamine receptor 1D0101
5-hydroxytryptamine receptor 1F0101
Sigma non-opioid intracellular receptor 10303
Platelet glycoprotein VI0225
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, N5-carboxyaminoimidazole ribonucleotide mutase0011
Chain B, N5-carboxyaminoimidazole ribonucleotide mutase0011
Chain A, N5-carboxyaminoimidazole ribonucleotide mutase0011
Chain B, N5-carboxyaminoimidazole ribonucleotide mutase0011
hepatocyte nuclear factor 4-alpha isoform 20101
perilipin-50101
perilipin-10101
1-acylglycerol-3-phosphate O-acyltransferase ABHD5 isoform a0101
Beta-lactamase0101
3-dehydroquinate dehydratase0011
ATP-citrate synthase 0001
Ribonuclease T0001
Cell death-related nuclease 40001
3-dehydroquinate dehydratase0011
Prolyl 4-hydroxylase0101
Alpha-ketoglutarate-dependent dioxygenase FTO0101
Phosphodiesterase 0101
Multidrug resistance-associated protein 50001
cGMP-inhibited 3',5'-cyclic phosphodiesterase B0303
cGMP-inhibited 3',5'-cyclic phosphodiesterase A0303
apical membrane antigen 1, AMA14004
urokinase-type plasminogen activator precursor1001
plasminogen precursor1001
urokinase plasminogen activator surface receptor precursor1001
Lysine-specific demethylase 4A0101
Hypoxia-inducible factor 1-alpha0011
Methylcytosine dioxygenase TET20101
Deoxyhypusine hydroxylase0101
Thymidine kinase 2 0101
Probable deoxycytidylate deaminase0001
Cytidine deaminase0002
AAA family ATPase 0002
Reverse transcriptase/RNaseH 04516
Ornithine transcarbamylase, mitochondrial0202
Nociceptin receptor0303
Chain A, POL POLYPROTEIN0101
Chain A, POL POLYPROTEIN0101
Chain B, POL POLYPROTEIN0101
Chain A, POL POLYPROTEIN0101
Chain B, POL POLYPROTEIN0101
Chain A, Pol Polyprotein0101
Chain B, Pol Polyprotein0101
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a5005
neuropeptide S receptor isoform A2002
Prothrombin 0101
Gag-Pol polyprotein0202
Gag-Pol polyprotein0101
Acetylcholinesterase0001
Cannabinoid receptor 10101
Microsomal triglyceride transfer protein large subunit0101
Disintegrin and metalloproteinase domain-containing protein 170101
Envelope glycoprotein gp160 [Cleaved into: Surface protein gp120 0101
Protease 0102
Fructose-1,6-bisphosphatase 1 0001
Reverse transcriptase 0112
Cholesterol 24-hydroxylase0011
pregnane X receptor5005
Albumin0336
Flavin reductase (NADPH)0011
Solute carrier family 15 member 10101
Chain A, BCL-2-RELATED PROTEIN A10011
unnamed protein product0101
heat shock protein HSP 90-alpha isoform 20001
bcl-2-like protein 11 isoform 10011
Beta-lactamase0101
Steroid 17-alpha-hydroxylase/17,20 lyase0101
Heme oxygenase 1 0101
ATP-dependent translocase ABCB10101
ATP-dependent translocase ABCB10708
Lanosterol 14-alpha demethylase0112
Aromatase0202
Cytochrome P450 11B1, mitochondrial0101
Cytochrome P450 11B2, mitochondrial0101
ATP-dependent translocase ABCB10101
Heme oxygenase 20101
Malate dehydrogenase, cytoplasmic0101
Histone deacetylase 40404
Cytochrome P450 1440011
Steroid C26-monooxygenase0011
Steroid C26-monooxygenase0011
Mycocyclosin synthase0011
Lanosterol 14-alpha demethylase0011
Lanosterol 14-alpha demethylase0011
Lanosterol 14-alpha demethylase0112
Sterol 14-alpha demethylase0011
Sterol 14-alpha demethylase0112
Histone deacetylase 70404
Polyamine deacetylase HDAC100404
Histone deacetylase 11 0404
14-alpha sterol demethylase 0011
Histone deacetylase 90404
Histone deacetylase 50404
heat shock protein 90, putative0001
likely tRNA 2'-phosphotransferase0101
Chain A, probable fosfomycin resistance protein0011
Chain B, probable fosfomycin resistance protein0011
DNA polymerase catalytic subunit0101
DNA polymerase catalytic subunit0101
DNA polymerase alpha catalytic subunit0101
DNA polymerase delta catalytic subunit0101
Glucose-6-phosphate 1-dehydrogenase0202
Corticosteroid 11-beta-dehydrogenase isozyme 10101
Adenosine receptor A10101
Cytochrome P450 2J20404
6-phosphogluconate dehydrogenase, decarboxylating0101
Holo-[acyl-carrier-protein] synthase0101
Solute carrier organic anion transporter family member 2A10101
G-protein coupled receptor 350112
CDGSH iron-sulfur domain-containing protein 10404
ubiquitin carboxyl-terminal hydrolase 2 isoform a1001
Voltage-dependent calcium channel subunit alpha-2/delta-10101
Gamma-aminobutyric acid 0011
Gamma-aminobutyric acid receptor subunit rho-30011
ATAD5 protein, partial3003
Hsf1 protein0022
bromodomain adjacent to zinc finger domain 2B5005
D(1A) dopamine receptor2002
histone-lysine N-methyltransferase 2A isoform 2 precursor3003
Gamma-aminobutyric acid receptor subunit pi0101
Gamma-aminobutyric acid receptor subunit delta0101
Gamma-aminobutyric acid type B receptor subunit 20011
Gamma-aminobutyric acid type B receptor subunit 20101
Gamma-aminobutyric acid receptor subunit alpha-10112
Gamma-aminobutyric acid receptor subunit alpha-60011
Gamma-aminobutyric acid receptor subunit beta-10112
Gamma-aminobutyric acid receptor subunit gamma-20112
Gamma-aminobutyric acid receptor subunit gamma-20011
Gamma-aminobutyric acid receptor subunit delta0011
Sodium- and chloride-dependent GABA transporter 10101
Gamma-aminobutyric acid receptor subunit rho-10022
Gamma-aminobutyric acid receptor subunit alpha-20011
Gamma-aminobutyric acid receptor subunit alpha-30011
Gamma-aminobutyric acid receptor subunit gamma-30011
Gamma-aminobutyric acid receptor subunit beta-30112
Gamma-aminobutyric acid receptor subunit rho-20011
Sodium- and chloride-dependent GABA transporter 10101
Sodium- and chloride-dependent taurine transporter0101
Gamma-aminobutyric acid receptor subunit alpha-50112
Sodium- and chloride-dependent GABA transporter 20101
Sodium- and chloride-dependent GABA transporter 30101
Sodium- and chloride-dependent GABA transporter 10101
Sodium- and chloride-dependent GABA transporter 20101
Sodium- and chloride-dependent GABA transporter 30101
Gamma-aminobutyric acid receptor subunit alpha-30112
Gamma-aminobutyric acid receptor subunit alpha-20112
Gamma-aminobutyric acid receptor subunit beta-20112
Sodium- and chloride-dependent betaine transporter0101
Sodium- and chloride-dependent betaine transporter0101
Sodium- and chloride-dependent GABA transporter 30101
Gamma-aminobutyric acid receptor subunit alpha-40112
Gamma-aminobutyric acid receptor subunit beta-10011
Gamma-aminobutyric acid receptor subunit alpha-10011
Gamma-aminobutyric acid receptor subunit beta-30011
Gamma-aminobutyric acid receptor subunit epsilon0101
4-aminobutyrate aminotransferase, mitochondrial0001
4-aminobutyrate aminotransferase, mitochondrial0001
Gamma-aminobutyric acid receptor subunit alpha-60112
Sterol O-acyltransferase 10011
Proton-coupled amino acid transporter 10101
Gamma-aminobutyric acid receptor subunit alpha-50011
Gamma-aminobutyric acid receptor subunit gamma-10101
Gamma-aminobutyric acid receptor subunit pi0011
Gamma-aminobutyric acid receptor subunit gamma-30101
Gamma-aminobutyric acid receptor subunit alpha-40011
Gamma-aminobutyric acid receptor subunit theta0011
Sodium- and chloride-dependent GABA transporter 20101
Gamma-aminobutyric acid receptor subunit gamma-10011
Gamma-aminobutyric acid type B receptor subunit 10011
Gamma-aminobutyric acid receptor subunit theta0101
Gamma-aminobutyric acid type B receptor subunit 10101
Chain A, DEOXYNUCLEOSIDE KINASE0101
Spike glycoprotein0011
Replicase polyprotein 1ab0011
Transmembrane protease serine 20011
Procathepsin L0011
Replicase polyprotein 1a0011
Replicase polyprotein 1ab0011
Equilibrative nucleoside transporter 10101
Alkaline phosphatase, tissue-nonspecific isozyme0202
Intestinal-type alkaline phosphatase0202
Phospholipase A-2-activating protein0202
cellular tumor antigen p53 isoform a2002
Integrin beta-31001
Integrin alpha-IIb1001
Chain A, Lectin0011
Chain A, Lectin0011
Chain A, Lectin0011
Chain A, Lectin0011
Chain A, ERYTHRINA CRISTA-GALLI LECTIN0011
Chain A, ERYTHRINA CRISTA-GALLI LECTIN0011
Chain A, cellulase0011
Chain A, cellulase0011
Chain A, Galectin-30011
Chain A, Anti-tumor lectin0101
Galectin-30101
Galectin-90011
Galectin-80011
Beta-galactoside-binding lectin0101
Galectin-10113
Galectin-30112
Galectin-30113
Galectin-70011
Alpha 1,4 galactosyltransferase0001
Voltage-dependent L-type calcium channel subunit alpha-1F0101
Voltage-dependent L-type calcium channel subunit alpha-1D 0101
Capsid protein 0123
Voltage-dependent L-type calcium channel subunit alpha-1S0101
Voltage-dependent L-type calcium channel subunit alpha-1C0202
Neprilysin0101
Angiotensin-converting enzyme 0202
Atrial natriuretic peptide receptor 30101
Type-1A angiotensin II receptor 0314
cAMP-specific 3',5'-cyclic phosphodiesterase 4A0101
Type-1 angiotensin II receptor0112
Type-2 angiotensin II receptor0303
cAMP-specific 3',5'-cyclic phosphodiesterase 4B0101
cAMP-specific 3',5'-cyclic phosphodiesterase 4C0101
cAMP-specific 3',5'-cyclic phosphodiesterase 4D0101
Type-1 angiotensin II receptor0213
5-hydroxytryptamine receptor 1A0101
Chain A, Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplast0101
Chain A, Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplast0101
Glutathione reductase, mitochondrial0202
ClpP2002
cytochrome P450 2D6 isoform 12002
peripheral myelin protein 22 isoform 13003
M-phase phosphoprotein 84004
Cytochrome P450 1A10101
Cytochrome P450 1A2 0101
Myeloperoxidase0202
Cholinesterase0101
Cytochrome P450 2C11 0101
Metabotropic glutamate receptor 10101
Acetylcholinesterase 0101
Alpha-1A adrenergic receptor0415
Melatonin receptor type 1A0213
Melatonin receptor type 1C0011
Melatonin receptor type 1A0112
Melatonin receptor type 1B0213
Melatonin receptor type 1C0112
Melatonin receptor type 1B0112
Nuclear factor erythroid 2-related factor 20001
Cytochrome P450 1B10101
Palmitoleoyl-protein carboxylesterase NOTUM0101
Carboxylic ester hydrolase 0101
Histamine H3 receptor0101
Prostaglandin E2 receptor EP1 subtype0101
Prostaglandin E2 receptor EP4 subtype0101
Prostaglandin F2-alpha receptor0101
Prostaglandin E2 receptor EP3 subtype0101
Prostaglandin E2 receptor EP2 subtype0101
Prostacyclin receptor0101
Prostaglandin D2 receptor0213
Prostaglandin D2 receptor 20101
glp-1 receptor, partial2002
Amyloid-beta precursor protein0202
Cholesteryl ester transfer protein0101
D-amino-acid oxidase0101
Hydroxycarboxylic acid receptor 30011
Nicotinamidase0101
Hydroxycarboxylic acid receptor 20011
Hydroxycarboxylic acid receptor 20213
D-aspartate oxidase0101
Hydroxycarboxylic acid receptor 20112
Chain A, NAD-dependent deacetylase0101
Poly [ADP-ribose] polymerase 20101
NAD-dependent histone deacetylase SIR20101
Coagulation factor VII0101
Poly [ADP-ribose] polymerase 10101
Tissue factor0202
Cytochrome P450 3A50112
NAD-dependent protein deacetylase HST20101
NAD(+) hydrolase SARM10101
NAD-dependent protein deacetylase sirtuin-20101
NAD-dependent protein deacetylase sirtuin-60101
NAD-dependent protein deacetylase sirtuin-10101
NAD-dependent protein deacetylase sirtuin-3, mitochondrial0101
NAD-dependent protein deacylase sirtuin-5, mitochondrial0202
NAD-dependent protein deacetylase 0101
Mcl-10101
pyruvate kinase PKM isoform a1001
Polyunsaturated fatty acid lipoxygenase ALOX15B2002
cGMP-specific 3',5'-cyclic phosphodiesterase0101
N(G),N(G)-dimethylarginine dimethylaminohydrolase 10202
Sodium/potassium-transporting ATPase subunit alpha-1 0202
Sodium/potassium-transporting ATPase subunit beta-10202
Sodium/potassium-transporting ATPase subunit alpha-30202
Sodium/potassium-transporting ATPase subunit beta-20202
Bifunctional cytochrome P450/NADPH--P450 reductase0011
UDP-glucuronosyltransferase 2B70203
Potassium-transporting ATPase subunit beta0101
Potassium-transporting ATPase alpha chain 10101
UDP-glucuronosyltransferase 1-60102
Potassium-transporting ATPase alpha chain 10101
UDP-glucuronosyltransferase 1A1 0202
UDP-glucuronosyltransferase 1A40101
Bombesin receptor subtype-30011
UDP-glucuronosyltransferase 2B10 0101
Histamine H2 receptor2002
Fatty acid synthase0404
Sodium/potassium-transporting ATPase subunit alpha-20202
Potassium-transporting ATPase subunit beta0101
Potassium-transporting ATPase alpha chain 20001
Sodium/potassium-transporting ATPase subunit beta-30202
Sodium/potassium-transporting ATPase subunit gamma0202
WD repeat-containing protein 50101
Glutathione S-transferase omega-10101
Histone-lysine N-methyltransferase 2A0101
Sodium/potassium-transporting ATPase subunit alpha-40202
Cytosolic endo-beta-N-acetylglucosaminidase0101
Muscarinic acetylcholine receptor0101
Chain A, ARGINASE 10101
Chain A, Arginase 10101
Chain A, ARGINASE 10101
Chain A, L-ARGININE\\:GLYCINE AMIDINOTRANSFERASE0101
Solute carrier family 22 member 20101
Solute carrier family 22 member 1 0202
Solute carrier family 22 member 30101
Indoleamine 2,3-dioxygenase 10202
Multidrug and toxin extrusion protein 20101
Indoleamine 2,3-dioxygenase 20202
Chain A, Hth-type Transcriptional Regulator Ttgr0011
Chain A, Hth-type Transcriptional Regulator Ttgr0011
Chain A, ATP-DEPENDENT DNA HELICASE Q12002
nonstructural protein 12002
glucocerebrosidase1001
serine-protein kinase ATM isoform a1001
cytochrome P450 2C9 precursor1001
DNA polymerase beta1001
fibroblast growth factor 22 isoform 1 precursor0002
serine/threonine-protein kinase 33 isoform a0011
Monocarboxylate transporter 40101
Pancreatic triacylglycerol lipase0101
Transthyretin0113
Estrogen receptor0516
Beta-lactamase0101
Solute carrier family 2, facilitated glucose transporter member 10101
Sodium/glucose cotransporter 10202
Sodium/glucose cotransporter 20101
Monocarboxylate transporter 10101
Monocarboxylate transporter 20101
Sodium/hydrogen exchanger 9B20101
Solute carrier family 28 member 30101
2-dehydropantoate 2-reductase0101
Fe(3+)-Zn(2+) purple acid phosphatase0101
Chain D, PROTEIN (PHOSPHOGLYCERATE MUTASE 1)0101
Chain A, PROTEIN (PHOSPHOGLYCERATE MUTASE 1)0101
Chain A, Beta-arrestin 10011
luciferase0001
Fatty acid-binding protein, liver0101
Glucocorticoid receptor06314
Progesterone receptor0416
Glucocorticoid receptor0112
Glucocorticoid receptor0011
Glycine receptor subunit alpha-10606
Glutamine synthetase0011
Glycine receptor subunit beta0606
Glycine receptor subunit alpha-20606
Glycine receptor subunit alpha-30606
Histamine H1 receptor0011
Nociceptin receptor0011
Estrogen receptor beta0314
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)3003
Beta-1 adrenergic receptor 0113
Voltage-dependent L-type calcium channel subunit alpha-1C0101
5-hydroxytryptamine receptor 40202
Beta-2 adrenergic receptor0213
Muscarinic acetylcholine receptor M20112
Beta-1 adrenergic receptor0213
5-hydroxytryptamine receptor 1A0101
Alpha-2A adrenergic receptor0124
Adenosine receptor A30314
Beta-2 adrenergic receptor0203
Muscarinic acetylcholine receptor M10112
Beta-3 adrenergic receptor0213
D(2) dopamine receptor0112
Alpha-1B adrenergic receptor0314
Beta-1 adrenergic receptor0214
Alpha-2C adrenergic receptor0124
D(3) dopamine receptor0101
Alpha-2B adrenergic receptor0011
Muscarinic acetylcholine receptor M30112
D(1A) dopamine receptor0112
Voltage-dependent L-type calcium channel subunit alpha-1C0101
Alpha-2C adrenergic receptor0011
Alpha-2A adrenergic receptor0011
Alpha-1D adrenergic receptor0213
Alpha-1D adrenergic receptor0012
Beta-3 adrenergic receptor0202
5-hydroxytryptamine receptor 1B0213
Neuromedin-K receptor0011
Sodium-dependent serotonin transporter0202
Cholecystokinin receptor type A0112
5-hydroxytryptamine receptor 70112
Beta-1 adrenergic receptor0101
Alpha-1A adrenergic receptor0124
Alpha-1B adrenergic receptor0012
Mu-type opioid receptor0224
Vasopressin V1a receptor0112
Delta-type opioid receptor0224
Kappa-type opioid receptor0224
5-hydroxytryptamine receptor 2B0415
5-hydroxytryptamine receptor 60213
5-hydroxytryptamine receptor 70101
Beta-2 adrenergic receptor0101
Sodium channel protein type 5 subunit alpha0101
Beta-2 adrenergic receptor0113
Nuclear receptor subfamily 2 group E member 10022
Chain A, dATP pyrophosphohydrolase0101
Chain A, Adenylate cyclase type 50101
Chain B, Adenylate cyclase type 20101
Angiotensin-converting enzyme0101
Butyrophilin subfamily 3 member A10124
4-hydroxy-3-methylbut-2-enyl diphosphate reductase0101
Farnesyl diphosphate synthase0101
H0202
Phosphotransferase 0101
Farnesyl diphosphate synthase0101
CDGSH iron-sulfur domain-containing protein 10101
Free fatty acid receptor 10011
Glutamate receptor ionotropic, NMDA 2D0011
Glutamate receptor ionotropic, NMDA 3B0011
Muscarinic acetylcholine receptor M10011
Muscarinic acetylcholine receptor M30011
Muscarinic acetylcholine receptor M40011
Muscarinic acetylcholine receptor M50011
Muscarinic acetylcholine receptor M20011
Tyrosine-protein phosphatase non-receptor type 10305
Carnitine O-palmitoyltransferase 2, mitochondrial0101
Amine oxidase [flavin-containing] B0202
Amine oxidase [flavin-containing] A 0101
Amine oxidase [flavin-containing] A0101
Catechol O-methyltransferase0011
Peroxisome proliferator-activated receptor alpha0112
Carnitine O-palmitoyltransferase 2, mitochondrial0101
Thromboxane-A synthase 0101
Amine oxidase [flavin-containing] B0202
Glutamate receptor ionotropic, NMDA 1 0012
Peroxisome proliferator-activated receptor gamma0247
Peroxisome proliferator-activated receptor gamma0011
C-C chemokine receptor type 20101
Cannabinoid receptor 20011
Carnitine O-palmitoyltransferase 1, liver isoform0101
Peroxisome proliferator-activated receptor delta0213
Glutamate receptor ionotropic, NMDA 10011
Peroxisome proliferator-activated receptor alpha0213
ATP-binding cassette sub-family C member 80101
Glutamate receptor ionotropic, NMDA 2A0011
Glutamate receptor ionotropic, NMDA 2B0011
ATP-sensitive inward rectifier potassium channel 110101
Glutamate receptor ionotropic, NMDA 2C0011
Thrombin 0011
CDGSH iron-sulfur domain-containing protein 20101
Glutamate receptor ionotropic, NMDA 3A0011
chaperonin-containing TCP-1 beta subunit homolog1001
Estrogen receptor beta0001
5'-AMP-activated protein kinase subunit beta-20001
Polymerase acidic protein0011
Stromelysin-10112
Tyrosine-protein phosphatase YopH0101
High mobility group protein B10011
Aldo-keto reductase family 1 member B10101
Prolyl 4-hydroxylase subunit alpha-10101
Estrogen receptor0001
Prostaglandin G/H synthase 10101
Cystathionine gamma-lyase0101
Solute carrier family 22 member 60103
Solute carrier family 22 member 70001
Nicotinate phosphoribosyltransferase0101
Solute carrier family 22 member 200101
Solute carrier family 22 member 80203
Solute carrier family 22 member 60101
Ubiquitin-like domain-containing CTD phosphatase 10101
5'-AMP-activated protein kinase subunit gamma-30001
5'-AMP-activated protein kinase subunit beta-10001
Nuclear receptor subfamily 1 group I member 20022
Sarcoplasmic/endoplasmic reticulum calcium ATPase 10101
Eukaryotic translation initiation factor 4E0011
Peptidyl-prolyl cis-trans isomerase FKBP1A0101
Alpha-synuclein1102
G protein-coupled receptor kinase 60011
Peptidyl-prolyl cis-trans isomerase FKBP1A0213
Peptidyl-prolyl cis-trans isomerase FKBP1B0011
Peptidyl-prolyl cis-trans isomerase FKBP50101
Uncharacterized aarF domain-containing protein kinase 50011
Programmed cell death protein 40011
ATP-dependent RNA helicase DHX300011
Regulatory-associated protein of mTOR0101
Target of rapamycin complex subunit LST80101
Serine/threonine-protein kinase mTOR 0101
Chain A, Mineralocorticoid receptor0101
Chain A, Mineralocorticoid receptor0101
parathyroid hormone/parathyroid hormone-related peptide receptor precursor2002
Vpr1001
Chain A, MALTOPORIN0011
Chain B, MALTOPORIN0011
Sodium/hydrogen exchanger 30101
Sodium/hydrogen exchanger 30101
Adenylate kinase isoenzyme 10001
Chain X, Thyroid hormone receptor beta-10011
Chain X, Thyroid hormone receptor beta-10011
peptidyl-prolyl cis-trans isomerase NIMA-interacting 11001
Solute carrier organic anion transporter family member 1A40001
Solute carrier organic anion transporter family member 1A50001
Thyroid hormone receptor alpha0011
Thyroid hormone receptor beta0011
Proliferating cell nuclear antigen0101
Malate dehydrogenase, mitochondrial0101
Solute carrier organic anion transporter family member 1A20001
Solute carrier organic anion transporter family member 1A30001
Solute carrier organic anion transporter family member 4C10101
Monocarboxylate transporter 80001
Bile acid receptor0101
Solute carrier organic anion transporter family member 1C10001
Chain A, Nuclear Receptor ROR-beta0101
Ornithine decarboxylase0001
Ornithine decarboxylase0001
Retinoic acid receptor alpha0227
Retinoic acid receptor beta0227
Retinoic acid receptor alpha0123
Retinoic acid receptor gamma 0227
Alpha-1A adrenergic receptor0101
Retinoic acid receptor gamma0123
Retinoic acid receptor beta0123
Cellular retinoic acid-binding protein 20011
Retinoic acid receptor RXR-alpha0123
Retinoic acid receptor RXR-beta0224
Retinoic acid receptor RXR-beta0123
Retinoic acid receptor RXR-gamma0123
Nuclear receptor ROR-alpha0101
Cellular retinoic acid-binding protein 10102
Retinoic acid receptor RXR-gamma0224
Cellular retinoic acid-binding protein 10011
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 10213
Nuclear receptor ROR-beta0101
Kappa-type opioid receptor0011
Chain A, Trp Rna-binding Attenuation Protein0011
Chain K, Trp Rna-binding Attenuation Protein0011
Chain B, tryptophanyl-tRNA synthetase0011
Chain C, Tryptophanyl-tRNA synthetase II0011
Dihydrofolate reductase0202
Plasma kallikrein0001
Indoleamine 2,3-dioxygenase 10102
Substance-P receptor0101
Tryptophan 2,3-dioxygenase0102
Glutamate receptor ionotropic, NMDA 2A 0001
Glutamate receptor ionotropic, NMDA 2C0001
Large neutral amino acids transporter small subunit 10101
SLC16A10 protein0001
Uracil nucleotide/cysteinyl leukotriene receptor0101
Carbonic anhydrase-like protein, putative0001
Tryprostatin B synthase0001
Glutamate receptor ionotropic, NMDA 2D0001
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase0011
Glutamate receptor ionotropic, NMDA 3B0001
Monocarboxylate transporter 100001
Glutamate receptor ionotropic, NMDA 3A0001
Malate dehydrogenase0101
Urease subunit alpha0101
Urease subunit beta0101
Olfactory receptor 51E20011
Chain A, Glycogen phosphorylase, liver form0011
Chain A, glycogen phosphorylase, liver form0011
Chain A, Glycogen phosphorylase, liver form0011
Chain A, Glycogen phosphorylase, liver form0011
Solute carrier family 2, facilitated glucose transporter member 90112
Guanine deaminase0101
Cocaine esterase0101
UDP-glucuronosyltransferase 1A90001
Aldo-keto reductase family 1 member B10101
Aldo-keto reductase family 1 member A10101
Liver carboxylesterase 10101
Aldo-keto reductase family 1 member A10101
Aldo-keto reductase family 1 member A10101
Aldo-keto reductase family 1 member B70101
Receptor-type tyrosine-protein phosphatase F0101
Tyrosine-protein phosphatase non-receptor type 20101
Tyrosine-protein phosphatase non-receptor type 60101
Tyrosine-protein phosphatase non-receptor type 110101
Albumin0011
Proprotein convertase subtilisin/kexin type 70101
Vitamin K epoxide reductase complex subunit 1-like protein 10101
Vitamin K epoxide reductase complex subunit 10101
Vitamin K epoxide reductase complex subunit 1-like protein 10101
Vitamin K epoxide reductase complex subunit 1 0202
72 kDa type IV collagenase0101
Matrix metalloproteinase-90101
Neutrophil collagenase0101
Farnesyl diphosphate synthase0101
Matrix metalloproteinase-140101
Geranylgeranyl pyrophosphate synthase0202
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]