Page last updated: 2024-11-05

thalidomide and Histiocytosis

thalidomide has been researched along with Histiocytosis in 5 studies

Thalidomide: A piperidinyl isoindole originally introduced as a non-barbiturate hypnotic, but withdrawn from the market due to teratogenic effects. It has been reintroduced and used for a number of immunological and inflammatory disorders. Thalidomide displays immunosuppressive and anti-angiogenic activity. It inhibits release of TUMOR NECROSIS FACTOR-ALPHA from monocytes, and modulates other cytokine action.
thalidomide : A racemate comprising equimolar amounts of R- and S-thalidomide.
2-(2,6-dioxopiperidin-3-yl)-1H-isoindole-1,3(2H)-dione : A dicarboximide that is isoindole-1,3(2H)-dione in which the hydrogen attached to the nitrogen is substituted by a 2,6-dioxopiperidin-3-yl group.

Histiocytosis: General term for the abnormal appearance of histiocytes in the blood. Based on the pathological features of the cells involved rather than on clinical findings, the histiocytic diseases are subdivided into three groups: HISTIOCYTOSIS, LANGERHANS CELL; HISTIOCYTOSIS, NON-LANGERHANS-CELL; and HISTIOCYTIC DISORDERS, MALIGNANT.

Research Excerpts

ExcerptRelevanceReference
"We evaluated thalidomide as a single agent in myeloma, myelodysplastic syndromes (MDS) and histiocytosis, i."7.71Thalidomide in multiple myeloma, myelodysplastic syndromes and histiocytosis. Analysis of clinical results and of surrogate angiogenesis markers. ( Alietti, A; Bertolini, F; Burlini, A; Cineri, S; Cinieri, S; Cocorocchio, E; Corsini, C; Ferrucci, PF; Mancuso, P; Martinelli, G; Mingrone, W; Peccatori, F; Zucca, E, 2001)
"Treatment with thalidomide stopped the progression of the disease in two cases."5.91Progressive mucinous histiocytosis treated successfully with thalidomide: a rare case report. ( Abdollahimajd, F; Diab, R; Kaddah, A; Rakhshan, A; Shahidi Dadras, M, 2023)
"We evaluated thalidomide as a single agent in myeloma, myelodysplastic syndromes (MDS) and histiocytosis, i."3.71Thalidomide in multiple myeloma, myelodysplastic syndromes and histiocytosis. Analysis of clinical results and of surrogate angiogenesis markers. ( Alietti, A; Bertolini, F; Burlini, A; Cineri, S; Cinieri, S; Cocorocchio, E; Corsini, C; Ferrucci, PF; Mancuso, P; Martinelli, G; Mingrone, W; Peccatori, F; Zucca, E, 2001)
"Treatment with thalidomide stopped the progression of the disease in two cases."1.91Progressive mucinous histiocytosis treated successfully with thalidomide: a rare case report. ( Abdollahimajd, F; Diab, R; Kaddah, A; Rakhshan, A; Shahidi Dadras, M, 2023)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (20.00)18.2507
2000's1 (20.00)29.6817
2010's2 (40.00)24.3611
2020's1 (20.00)2.80

Authors

AuthorsStudies
Diab, R1
Shahidi Dadras, M1
Rakhshan, A1
Kaddah, A1
Abdollahimajd, F1
Tóth, B1
Katona, M1
Hársing, J1
Szepesi, A1
Kárpáti, S1
Hu, X1
Liu, J1
Bai, C1
Wang, J1
Song, X1
Saano, V1
Bertolini, F1
Mingrone, W1
Alietti, A1
Ferrucci, PF1
Cocorocchio, E1
Peccatori, F1
Cinieri, S1
Mancuso, P1
Corsini, C1
Burlini, A1
Zucca, E1
Martinelli, G1
Cineri, S1

Reviews

1 review available for thalidomide and Histiocytosis

ArticleYear
[New therapeutic application of thalidomide].
    Duodecim; laaketieteellinen aikakauskirja, 1996, Volume: 112, Issue:7

    Topics: Autoimmune Diseases; Colitis, Ulcerative; Erythema Multiforme; Female; Histiocytosis; Humans; Immuno

1996

Other Studies

4 other studies available for thalidomide and Histiocytosis

ArticleYear
Progressive mucinous histiocytosis treated successfully with thalidomide: a rare case report.
    The Journal of dermatological treatment, 2023, Volume: 34, Issue:1

    Topics: Adult; Female; Histiocytosis; Humans; Skin Diseases; Skin Neoplasms; Thalidomide

2023
Indeterminate cell histiocytosis in a pediatric patient: successful treatment with thalidomide.
    Pathology oncology research : POR, 2012, Volume: 18, Issue:2

    Topics: Adolescent; Histiocytosis; Humans; Immunosuppressive Agents; Male; Skin Diseases; Thalidomide; Treat

2012
Bortezomib combined with thalidomide and dexamethasone is effective for patient with crystal-storing histiocytosis associated with monoclonal gammopathy of undermined significance.
    European journal of haematology, 2012, Volume: 89, Issue:2

    Topics: Angiogenesis Inhibitors; Antineoplastic Agents, Hormonal; Boronic Acids; Bortezomib; Dexamethasone;

2012
Thalidomide in multiple myeloma, myelodysplastic syndromes and histiocytosis. Analysis of clinical results and of surrogate angiogenesis markers.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2001, Volume: 12, Issue:7

    Topics: Aged; Aged, 80 and over; Angiogenesis Inhibitors; Biomarkers, Tumor; Endothelial Growth Factors; Fem

2001