clofazimine has been researched along with Histiocytosis in 4 studies
Clofazimine: A fat-soluble riminophenazine dye used for the treatment of leprosy. It has been used investigationally in combination with other antimycobacterial drugs to treat Mycobacterium avium infections in AIDS patients. Clofazimine also has a marked anti-inflammatory effect and is given to control the leprosy reaction, erythema nodosum leprosum. (From AMA Drug Evaluations Annual, 1993, p1619)
clofazimine : 3-Isopropylimino-3,5-dihydro-phenazine in which the hydrogen at position 5 is substituted substituted by a 4-chlorophenyl group, and that at position 2 is substituted by a (4-chlorophenyl)amino group. A dark red crystalline solid, clofazimine is an antimycobacterial and is one of the main drugs used for the treatment of multi-bacillary leprosy. However, it can cause red/brown discolouration of the skin, so other treatments are often preferred in light-skinned patients.
Histiocytosis: General term for the abnormal appearance of histiocytes in the blood. Based on the pathological features of the cells involved rather than on clinical findings, the histiocytic diseases are subdivided into three groups: HISTIOCYTOSIS, LANGERHANS CELL; HISTIOCYTOSIS, NON-LANGERHANS-CELL; and HISTIOCYTIC DISORDERS, MALIGNANT.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Clofazimine-induced crystal-storing histiocytosis is a rare but well-recognized condition in the literature." | 7.70 | Clofazimine-induced crystal-storing histiocytosis producing chronic abdominal pain in a leprosy patient. ( Akaraviputh, T; Chanchairujira, T; Hargrove, NS; Kachintorn, U; Manatsathit, S; Siritanaratkul, N; Sukpanichnant, S; Thakerngpol, K, 2000) |
| "Clofazimine-induced crystal-storing histiocytosis is a rare but well-recognized condition in the literature." | 3.70 | Clofazimine-induced crystal-storing histiocytosis producing chronic abdominal pain in a leprosy patient. ( Akaraviputh, T; Chanchairujira, T; Hargrove, NS; Kachintorn, U; Manatsathit, S; Siritanaratkul, N; Sukpanichnant, S; Thakerngpol, K, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (50.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 1 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Divate, S | 1 |
| Sharma, S | 1 |
| Dhillon, AS | 1 |
| Johnston, EL | 1 |
| Sanderson, JD | 1 |
| Pais, AV | 1 |
| Pereira, S | 1 |
| Garg, I | 1 |
| Stephen, J | 1 |
| Antony, M | 1 |
| Inchara, YK | 1 |
| Sukpanichnant, S | 1 |
| Hargrove, NS | 1 |
| Kachintorn, U | 1 |
| Manatsathit, S | 1 |
| Chanchairujira, T | 1 |
| Siritanaratkul, N | 1 |
| Akaraviputh, T | 1 |
| Thakerngpol, K | 1 |
1 review available for clofazimine and Histiocytosis
| Article | Year |
|---|---|
Intra-abdominal, crystal-storing histiocytosis due to clofazimine in a patient with lepromatous leprosy and concurrent carcinoma of the colon.
Topics: Abdominal Pain; Adenocarcinoma; Adult; Clofazimine; Colonic Neoplasms; Crystallization; Female; Hist | 2004 |
3 other studies available for clofazimine and Histiocytosis
| Article | Year |
|---|---|
Pulmonary clofazimine-induced crystal-storing histiocytosis: Bronchoalveolar lavage cytological diagnosis.
Topics: Bronchoalveolar Lavage; Clofazimine; Histiocytosis; Humans; Lung; Rare Diseases | 2020 |
A Case of Unusual Ileal Discoloration.
Topics: Clofazimine; Crohn Disease; Histiocytosis; Humans; Ileal Diseases; Leprostatic Agents; Male; Mycobac | 2018 |
Clofazimine-induced crystal-storing histiocytosis producing chronic abdominal pain in a leprosy patient.
Topics: Abdominal Pain; Adult; Biopsy; Chronic Disease; Clofazimine; Crystallization; Cytoplasm; Diagnosis, | 2000 |