Pre-Hypertension

Blood pressure levels that are between normotension and hypertension. Individuals with prehypertension are at a higher risk for developing cardiovascular diseases. Generally, prehypertension is defined as SYSTOLIC PRESSURE of 131-139 mm Hg and/or DIASTOLIC PRESSURE of 81-89 when the optimal is 120/80 mm Hg. For diabetics and other metabolism diseases the prehypertension is around 110-129/70-79 mm Hg.

Synonym
Prehypertension
Pre-Hypertension

Excerpt	Reference
"Prehypertension is associated with impaired NO-mediated endothelium-dependent vasodilation."	( DeSouza, CA; Greiner, JJ; Stauffer, BL; Weil, BR, 2011)
"Prehypertension is associated with oxidative stress and increased arterial stiffness."	( Huh, JK; Kang, JH; Kim, BJ; Kim, BS; Kim, JT; Kwon, CH; Seo, M; Sung, KC, 2011)
"Prehypertension is a preclinical stage where primary prevention efforts have been recommended for delaying or preventing the onset of hypertension."	( Sabanayagam, C; Shankar, A; Somasundaram, S, 2012)
"Like hypertension, prehypertension is associated with cardiovascular disease."	( Frysak, Z; Halenka, M; Jackuliakova, D; Karasek, D; Novotny, D; Orsag, J; Vaverkova, H, 2013)
"Prehypertension is highly prevalent in urban population of India, more often seen in persons below 50 years of age."	( Amarkhed, B; Ambar, S; Halkati, PC; Patil, R; Patted, SV; Porwal, SC; Yavagal, ST, 2013)
"Prehypertension is a risk factor for atherosclerosis."	( Jung, S; Kim, M; Kim, SY; Lee, JH; Lee, SH, 2014)
""Prehypertension" is the clinical stage leading to hypertension."	( Biswas, OS; Gonzalez, VR; Schwarz, ER, 2015)
"Prehypertension is an important phenotype for cardiovascular risk and development of established hypertension."	( Delafontaine, P; Egan, P; Fernandez, C; Giles, TD; Kandavar, R; Kim, C; Roffidal, LE; Sander, GE; Sukhanov, S; Velaga, S, 2015)
"Prehypertension is one of the most common conditions affecting human beings worldwide."	( Fatt, QK; Oldenburg, B; Parthaje, PM; Thankappan, KR; Thapar, R; Unnikrishnan, B, 2016)
"Prehypertension is a risk factor for the development of hypertension and other cardiovascular diseases."	( Chen, YH; Yi, H; Zhang, H; Zhang, WZ; Zhou, MC, 2017)
"Prehypertension is not categorized as a disease currently; however, individuals with untreated prehypertension are known to be at increased risk of progression to hypertension and mortality caused by cardiovascular disease."	( Jung, PK; Lee, JH; Lee, S; Lee, W; Rhie, J; Roh, J; Seok, H; Won, JU; Yoon, JH, 2016)
"Prehypertension is a state of above-normal blood pressure that does not meet the criteria for the diagnosis of hypertension and its prevalence estimated in population-based samples ranges from 22 to 52%."	( Itrat, M; Khan, MI; Mobeen, A; Siddiqui, MA, 2021)

Excerpt	Reference
"Prehypertension has recently been observed as a potent cardiovascular risk factor."	( Adithan, C; Amudharaj, D; Dutta, TK; Lalitha, V; Nanda, N; Pal, GK; Pal, P, 2012)
"Prehypertension has been shown to be an early risk factor of cardiovascular disease (CVD)."	( Chiang, PP; Lamoureux, EL; Sabanayagam, C; Shankar, A; Tai, ES; Wong, TY, 2013)
"Prehypertension has been associated with adverse cerebrovascular events and brain damage."	( He, DH; Lin, JX; Lin, LM; Ning, RB; Wang, HJ; Xu, CS; Zhang, LM, 2014)

Timeframe	Studies, This Condition (%)	All Conditions %
pre-1990	1 (0.40)	23.3326
1990's	0 (0.00)	12.5806
2000's	0 (0.00)	18.1394
2010's	210 (84.00)	28.8240
2020's	39 (15.60)	9.53

Drug	Relationship Strength	Studies	Trials
gamma-aminobutyric acid	low	1	0
n(g),n(g')-dimethyl-l-arginine	medium	2	1
iodine	low	1	0
kynurenine	low	1	0
melatonin	low	1	0
nitrates	medium	2	1
nitrites	medium	2	2
phthalic acid	low	1	0
purine	low	1	0
sulfur dioxide	low	1	0
taurine	medium	1	1
uric acid	medium	33	5
urea	low	1	0
amlodipine	low	2	0
aspirin	medium	1	1
berberine	low	1	0
caffeine	medium	1	1
candesartan	medium	2	1
chlorthalidone	medium	2	2
hydralazine	low	1	0
hydrochlorothiazide	medium	2	1
isoproterenol	low	1	0
losartan	low	3	0
methylphenidate	medium	1	1
potassium chloride	medium	1	1
probenecid	medium	1	1
thyroxine	low	1	0
aldosterone	medium	4	1
tryptophan	low	1	0
arginine	medium	4	2
catechin	medium	1	1
citrulline	medium	1	1
malondialdehyde	medium	4	2
potassium citrate	medium	1	1
d-alpha tocopherol	medium	1	1
amiloride	medium	3	3
fructosamine	low	1	0
cadmium	low	2	0
ozone	low	1	0
captopril	low	2	0
cicletanine	medium	2	1
glucose, (beta-d)-isomer	medium	3	1
nicotine	low	1	0
fibrinogen	low	1	0
equol	medium	4	4
homocysteine	low	2	0
procyanidin	medium	1	1
angiotensin ii, des-phe(8)-	low	2	0
n,n-dimethylarginine	medium	2	1
omega-n-methylarginine	low	1	0
symmetric dimethylarginine	medium	1	1
angiotensin ii	low	9	0
n-acetylneuraminic acid	low	2	0
bradykinin	low	1	0
bq 123	low	2	0
resveratrol	low	1	0
cocaine	medium	1	1
eicosapentaenoic acid	medium	2	1
stilbenes	low	1	0
D-fructopyranose	medium	2	2
nitrogen dioxide	low	1	0
quercetin	medium	3	3
bilirubin	low	3	0
dinoprost	medium	3	1
cholecalciferol	medium	4	2
6-ketoprostaglandin f1 alpha	medium	1	1
astaxanthine	low	1	0
daidzein	medium	5	5
8-epi-prostaglandin f2alpha	medium	3	1
sirolimus	low	1	0
lysophosphatidylcholines	medium	2	1
lead	low	5	0
enalapril	medium	1	1
fumarates	medium	3	2
phosphorus	medium	1	1
aliskiren	medium	3	2
25-hydroxyvitamin d 2	low	1	0
dapagliflozin	medium	3	1
isoleucyl-prolyl-proline	medium	1	1
tribulus	medium	1	1
pituitrin	low	1	0
glucagon	low	1	0
beta-endorphin	low	1	0
neuropeptide y	low	1	0
angiotensinogen	low	1	0
glucagon-like peptide 1	low	1	0
endothelin-1	medium	7	3
phosphatidylcholines	low	1	0
chitosan	medium	1	1
potassium-magnesium citrate	medium	1	1
sodium glutamate	low	1	0
interleukin-8	medium	1	1
isoquercitrin	medium	1	1
natriuretic peptide, brain	low	1	0
heme	low	1	0
phytoestrogens	medium	3	3
caseins	medium	1	1
angiotensin i	low	3	0
adrenomedullin	low	1	0
muramidase	medium	1	1
exudates	low	3	0
cyclic gmp	low	1	0
folic acid	low	1	0
7,8-dihydrobiopterin	medium	1	1
allopurinol	medium	4	2
maltodextrin	medium	1	1
leptin	medium	2	1

Protein Targets (1,327)

Protein	Potency Measurements	Inhibition Measurements	Activation Measurements	Drugs
Solute carrier organic anion transporter family member 2A1	0	1	0	3
Chain A, Tyrosine 3-monooxygenase	0	1	0	1
aldehyde dehydrogenase 1 family, member A1	17	0	0	17
AR protein	22	0	0	22
glucocorticoid receptor [Homo sapiens]	17	0	0	17
thyroid hormone receptor beta isoform a	9	0	0	9
nuclear factor erythroid 2-related factor 2 isoform 2	2	0	0	2
geminin	17	0	0	17
Sex hormone-binding globulin	0	0	1	1
Corticosteroid-binding globulin	0	1	0	1
Mineralocorticoid receptor	0	1	2	3
Androgen receptor	0	2	0	2
Mineralocorticoid receptor	0	1	0	1
Solute carrier organic anion transporter family member 1A1	0	1	0	4
Guanine nucleotide-binding protein G	2	0	0	2
Fumarate hydratase	2	0	0	2
polyprotein	2	0	0	2
Pepsin A	0	1	0	1
Renin	0	3	0	3
Renin-1	0	1	0	1
Renin	0	1	0	1
Cytochrome P450 3A4	0	7	0	8
Cytochrome P450 2C9	0	7	0	7
Cathepsin D	0	1	0	1
Renin	0	1	0	1
Renin	0	1	0	1
Protease	0	1	0	1
interleukin 8	5	0	0	5
TDP1 protein	12	0	0	12
thyroid stimulating hormone receptor	10	0	0	10
estrogen receptor 2 (ER beta)	4	0	0	4
progesterone receptor	6	0	0	6
estrogen-related nuclear receptor alpha	18	0	0	18
estrogen nuclear receptor alpha	23	0	0	23
IDH1	5	0	0	5
euchromatic histone-lysine N-methyltransferase 2	23	0	0	23
Bloom syndrome protein isoform 1	11	0	0	11
transcriptional regulator ERG isoform 3	2	0	0	2
thyroid hormone receptor beta isoform 2	11	0	0	11
ras-related protein Rab-9A	6	0	0	6
nuclear factor erythroid 2-related factor 2 isoform 1	15	0	0	15
survival motor neuron protein isoform d	10	0	0	10
lamin isoform A-delta10	18	0	0	18
ATP-binding cassette sub-family C member 3	0	12	0	12
Multidrug resistance-associated protein 4	0	12	0	14
Polyphenol oxidase 2	0	3	0	4
Voltage-dependent calcium channel gamma-2 subunit	8	0	0	8
Bile salt export pump	0	18	0	18
Hypoxanthine-guanine phosphoribosyltransferase	0	0	0	1
Cellular tumor antigen p53	11	0	0	11
Glutamate receptor 2	8	0	0	8
Xanthine dehydrogenase/oxidase [Includes: Xanthine dehydrogenase	0	1	0	1
Adenosine receptor A2a	0	3	2	6
Xanthine dehydrogenase/oxidase	0	6	0	6
Nuclear receptor ROR-gamma	0	1	0	1
Xanthine dehydrogenase/oxidase	0	4	1	7
Purine nucleoside phosphorylase	0	0	1	1
TAR DNA-binding protein 43	4	0	0	4
Canalicular multispecific organic anion transporter 1	0	13	0	13
Shiga toxin subunit A	0	1	0	1
Histamine H3 receptor	0	1	0	1
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE	14	0	0	14
Chain U, UROKINASE-TYPE PLASMINOGEN ACTIVATOR	0	1	0	1
Chain A, UROKINASE-TYPE PLASMINOGEN ACTIVATOR	0	1	0	1
Chain A, UROKINASE-TYPE PLASMINOGEN ACTIVATOR	0	1	0	1
Chain A, HADH2 protein	11	0	0	11
Chain B, HADH2 protein	11	0	0	11
Chain A, 2-oxoglutarate Oxygenase	13	0	0	13
acid sphingomyelinase	3	0	0	3
acetylcholinesterase	4	0	0	4
thioredoxin reductase	16	0	0	16
regulator of G-protein signaling 4	11	0	0	11
glucocerebrosidase	6	0	0	6
arylsulfatase A	12	0	0	12
alpha-galactosidase	4	0	0	4
cytochrome P450 2D6 isoform 1	6	0	0	6
lysosomal alpha-glucosidase preproprotein	3	0	0	3
cytochrome P450 2C19 precursor	7	0	0	7
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1	8	0	0	8
huntingtin isoform 2	2	0	0	2
Membrane primary amine oxidase	0	1	0	1
Solute carrier family 22 member 1	0	1	0	3
Prothrombin	0	4	2	6
Coagulation factor X	0	1	0	1
Plasminogen	0	1	0	1
Urokinase-type plasminogen activator	0	3	0	3
Tissue-type plasminogen activator	0	2	0	2
Cationic trypsin	0	2	0	2
Coagulation factor XI	0	1	0	1
Plasma kallikrein	0	1	0	2
Vitamin K-dependent protein C	0	1	0	1
Urokinase-type plasminogen activator	0	2	0	2
Trypsin-1	0	2	0	2
Trypsin-2	0	2	0	2
Sodium/hydrogen exchanger 1	0	1	0	1
Amine oxidase [flavin-containing] A	0	5	0	5
Sodium/hydrogen exchanger 1	0	2	0	2
Sodium/hydrogen exchanger 3	0	2	0	2
Trypsin-3	0	2	0	2
Amiloride-sensitive sodium channel subunit alpha	0	1	0	1
5-hydroxytryptamine receptor 7	0	1	0	1
Sodium/hydrogen exchanger 2	0	2	0	2
Acid-sensing ion channel 1	0	1	0	1
Potassium voltage-gated channel subfamily H member 2	0	4	0	4
Sodium channel protein type 5 subunit alpha	0	1	0	1
Sodium/hydrogen exchanger 5	0	2	0	2
Solute carrier family 22 member 1	0	3	0	3
Solute carrier family 22 member 2	0	3	0	3
Acid-sensing ion channel 3	0	1	0	1
Sodium/hydrogen exchanger	0	1	0	1
Chain A, Ferritin light chain	5	0	0	5
Smad3	5	0	0	5
cytochrome P450 family 3 subfamily A polypeptide 4	10	0	0	10
G	6	0	0	6
cytochrome P450 2D6	6	0	0	6
chromobox protein homolog 1	13	0	0	13
NEDD8-activating enzyme E1 regulatory subunit isoform a	0	1	0	1
NEDD8-conjugating enzyme Ubc12	0	1	0	1
nuclear receptor ROR-gamma isoform 1	7	0	0	7
histone acetyltransferase KAT2A isoform 1	9	0	0	9
Voltage-dependent L-type calcium channel subunit alpha-1C	0	1	0	1
Potassium channel subfamily K member 2	0	1	2	3
Interferon beta	7	0	0	7
HLA class I histocompatibility antigen, B alpha chain	6	0	0	6
ATP-dependent translocase ABCB1	0	4	1	7
Alpha-2A adrenergic receptor	0	2	0	2
Alpha-2C adrenergic receptor	0	2	0	2
Alpha-2B adrenergic receptor	0	4	0	4
Voltage-dependent L-type calcium channel subunit alpha-1C	0	1	0	1
Alpha-2C adrenergic receptor	0	4	0	4
Alpha-2A adrenergic receptor	0	4	0	4
Alpha-1D adrenergic receptor	0	1	1	2
Alpha-1A adrenergic receptor	0	1	1	2
Alpha-1B adrenergic receptor	0	1	1	2
5-hydroxytryptamine receptor 6	0	2	0	2
Spike glycoprotein	3	0	1	4
Sodium-dependent dopamine transporter	0	6	0	6
Voltage-dependent L-type calcium channel subunit alpha-1C	0	1	0	1
Potassium channel subfamily K member 2	0	1	0	1
Inositol hexakisphosphate kinase 1	6	0	0	6
cytochrome P450 2C9, partial	6	0	0	6
DNA polymerase kappa isoform 1	11	0	0	11
Atrial natriuretic peptide receptor 3	0	2	0	2
Type-1A angiotensin II receptor	0	4	3	7
Type-1 angiotensin II receptor	0	0	1	1
Type-1B angiotensin II receptor	0	4	0	4
Type-1 angiotensin II receptor	0	6	3	12
Type-2 angiotensin II receptor	0	5	0	5
Type-2 angiotensin II receptor	0	4	0	4
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	1	1
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	1	1
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	1	1
phosphopantetheinyl transferase	11	0	0	11
NFKB1 protein, partial	4	0	0	4
GLS protein	11	0	0	11
flap endonuclease 1	5	0	0	5
DNA polymerase iota isoform a (long)	7	0	0	7
muscarinic acetylcholine receptor M1	6	0	0	6
lethal factor (plasmid)	4	0	0	4
Nitric oxide synthase, endothelial	0	1	0	3
Nitric oxide synthase, brain	0	4	0	5
Nitric oxide synthase, brain	0	4	0	5
Nitric oxide synthase, inducible	0	3	0	4
Nitric oxide synthase, inducible	0	2	1	5
Cationic amino acid transporter 3	0	1	0	1
ATP-dependent phosphofructokinase	11	0	0	11
vitamin D3 receptor isoform VDRA	6	0	0	6
peripheral myelin protein 22	7	0	0	7
Translocator protein	0	1	1	2
Vasopressin V2 receptor	0	3	1	5
Oxytocin receptor	0	1	1	2
Vasopressin V1a receptor	0	0	3	3
Vasopressin V1a receptor	0	1	1	2
Vasopressin V1b receptor	0	1	1	2
Vasopressin V2 receptor	0	0	1	1
Vasopressin V1b receptor	0	1	1	3
Translocator protein	0	1	0	2
Oxytocin receptor	0	1	1	2
Vasopressin V2 receptor	0	1	1	2
Chain A, TYROSYL-DNA PHOSPHODIESTERASE	7	0	0	7
Chain A, Phospholipase A2 isoform 3	0	0	1	1
GTP-binding protein (rab7)	0	0	1	1
ras protein, partial	0	0	1	1
hypothetical protein, conserved	1	0	0	1
EWS/FLI fusion protein	8	0	0	8
retinoic acid nuclear receptor alpha variant 1	15	0	0	15
peroxisome proliferator-activated receptor delta	8	0	0	8
Rac1 protein	0	0	1	1
cell division cycle 42 (GTP binding protein, 25kDa), partial	0	0	1	1
Prostaglandin-H2 D-isomerase	0	1	0	1
Solute carrier family 22 member 6	0	3	0	3
Prostaglandin G/H synthase 1	0	4	0	4
Prostaglandin G/H synthase 2	0	2	0	2
Epidermal growth factor receptor	0	3	1	4
Carbonic anhydrase 1	0	13	0	15
Carbonic anhydrase 2	0	15	0	17
Fatty acid-binding protein, liver	0	1	0	1
Integrin beta-3	4	1	0	5
Myeloperoxidase	0	5	0	5
Prostaglandin G/H synthase 1	0	2	2	4
Seed linoleate 13S-lipoxygenase-1	0	2	0	4
Integrin alpha-IIb	4	1	0	5
Glutathione hydrolase 1 proenzyme	0	1	0	1
Prostaglandin G/H synthase 1	0	6	0	6
Adenosine receptor A1	0	5	0	6
Adenosine receptor A2a	0	6	0	8
Substance-P receptor	0	4	0	4
Prostaglandin G/H synthase 2	0	7	0	7
Urotensin-2 receptor	0	1	0	1
4-aminobutyrate aminotransferase, mitochondrial	0	1	0	1
Nuclear receptor ROR-gamma	7	0	0	7
Ras-related protein Rab-2A	0	0	1	1
Gamma-aminobutyric acid receptor subunit alpha-1	8	3	1	12
Prostaglandin G/H synthase 2	0	4	0	4
Rho-associated protein kinase 2	0	1	0	1
Nicotinate phosphoribosyltransferase	0	1	0	1
Solute carrier family 22 member 20	0	2	0	2
Solute carrier family 22 member 6	0	2	0	2
Sigma non-opioid intracellular receptor 1	0	2	1	3
Sigma non-opioid intracellular receptor 1	0	0	1	1
Chain A, Putative fructose-1,6-bisphosphate aldolase	7	0	0	7
PPM1D protein	1	0	0	1
Microtubule-associated protein tau	14	0	0	14
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	4	0	0	4
cytochrome P450 3A4 isoform 1	8	0	0	8
Gamma-aminobutyric acid receptor subunit pi	8	2	0	10
Telomerase reverse transcriptase	0	1	0	1
Acetylcholinesterase	0	2	0	2
Lysine-specific histone demethylase 1A	0	3	0	3
Neuraminidase	0	2	0	2
Neuraminidase	0	1	0	1
Cholinesterase	0	4	1	5
Gamma-aminobutyric acid receptor subunit beta-1	8	2	0	10
Tyrosine-protein phosphatase non-receptor type 1	0	3	0	3
Gamma-aminobutyric acid receptor subunit delta	8	2	0	10
Gamma-aminobutyric acid receptor subunit gamma-2	8	2	1	11
Gamma-aminobutyric acid receptor subunit alpha-5	8	2	0	10
Gamma-aminobutyric acid receptor subunit alpha-3	8	2	0	10
Acetylcholinesterase	0	5	0	5
Gamma-aminobutyric acid receptor subunit gamma-1	8	2	0	10
Gamma-aminobutyric acid receptor subunit alpha-2	8	2	0	10
Gamma-aminobutyric acid receptor subunit alpha-4	8	2	0	10
Gamma-aminobutyric acid receptor subunit gamma-3	8	2	0	10
Gamma-aminobutyric acid receptor subunit alpha-6	8	2	0	10
Aldo-keto reductase family 1 member C3	0	1	0	1
Prolyl endopeptidase	0	2	0	2
Aldo-keto reductase family 1 member C2	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-3	8	2	0	10
Gamma-aminobutyric acid receptor subunit beta-2	8	2	1	11
Cholinesterase	0	2	0	2
Inositol monophosphatase 1	6	0	0	6
Cytochrome P450 1B1	0	7	1	8
GABA theta subunit	8	2	0	10
Gamma-aminobutyric acid receptor subunit epsilon	8	2	0	10
Chain A, Cruzipain	5	0	0	5
USP1 protein, partial	12	0	0	12
caspase-1 isoform alpha precursor	1	0	0	1
Caspase-7	1	0	0	1
Solute carrier organic anion transporter family member 1B3	0	4	0	5
Solute carrier organic anion transporter family member 1B1	0	5	0	7
Solute carrier organic anion transporter family member 1A4	0	1	0	3
Multidrug resistance-associated protein 6	0	0	0	1
Solute carrier organic anion transporter family member 1A5	0	0	0	2
Endothelin receptor type B	0	1	0	1
Endothelin-1 receptor	0	2	0	3
Endothelin-1 receptor	1	1	0	2
Endothelin-1 receptor	0	1	0	1
Canalicular multispecific organic anion transporter 1	0	2	0	3
Solute carrier organic anion transporter family member 1B2	0	0	0	1
Angiotensin-converting enzyme	0	4	1	6
B2 bradykinin receptor	0	1	0	1
B2 bradykinin receptor	0	2	1	5
B1 bradykinin receptor	0	1	0	1
Olfactory receptor 51E2	0	0	2	2
Chain A, Glycogen Phosphorylase	0	1	0	1
Chain A, Glycogen phosphorylase, liver form	0	0	2	2
Chain A, glycogen phosphorylase, liver form	0	0	2	2
Chain A, Glycogen phosphorylase, liver form	0	0	2	2
Chain A, Glycogen phosphorylase, liver form	0	0	2	2
Chain A, Chitinase	0	1	0	1
RAR-related orphan receptor gamma	12	0	0	12
GLI family zinc finger 3	14	0	0	14
nuclear receptor subfamily 1, group I, member 3	13	0	0	13
retinoid X nuclear receptor alpha	9	0	0	9
farnesoid X nuclear receptor	5	0	0	5
pregnane X nuclear receptor	11	0	0	11
thyroid stimulating hormone receptor	7	0	0	7
v-jun sarcoma virus 17 oncogene homolog (avian)	7	0	0	7
atrial natriuretic peptide receptor 1 precursor	1	0	0	1
DNA polymerase beta	5	0	0	5
Glycogen phosphorylase, muscle form	0	2	0	2
Glycogen phosphorylase, liver form	0	1	0	1
Glycogen phosphorylase, muscle form	0	1	0	1
Replicase polyprotein 1ab	0	4	1	5
Adenosine receptor A3	0	4	0	4
Replicase polyprotein 1ab	0	3	1	4
Amine oxidase [flavin-containing] B	0	5	0	5
cAMP-specific 3',5'-cyclic phosphodiesterase 4A	0	3	0	3
Adenosine receptor A3	0	1	0	1
Adenosine receptor A2b	0	1	0	2
Adenosine receptor A2b	0	2	0	3
Adenosine receptor A1	0	1	1	4
Vasopressin V2 receptor	0	0	0	1
Serine/threonine-protein kinase mTOR	0	2	1	3
Adenosine receptor A2a	0	1	0	1
Adenosine receptor A1	0	1	0	1
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	0	2	0	2
DNA-dependent protein kinase catalytic subunit	0	1	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B	0	2	0	2
Adenylate cyclase type 1	0	0	0	1
Chitotriosidase-1	0	1	0	1
Serine-protein kinase ATM	0	1	0	1
Serine/threonine-protein kinase ATR	0	1	0	1
Adenosine receptor A2b	0	1	0	2
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C	0	2	0	2
Palmitoleoyl-protein carboxylesterase NOTUM	0	2	2	4
Endochitinase B1	0	1	0	1
Muscarinic acetylcholine receptor	0	0	0	1
Phosphodiesterase	0	2	0	2
Broad substrate specificity ATP-binding cassette transporter ABCG2	0	4	1	5
Guanine deaminase	0	2	0	2
potassium voltage-gated channel subfamily H member 2 isoform d	1	0	0	1
Receptor tyrosine-protein kinase erbB-2	0	1	0	1
Aldo-keto reductase family 1 member B1	0	6	0	6
60 kDa chaperonin	0	2	0	2
60 kDa heat shock protein, mitochondrial	0	2	0	2
Beta-3 adrenergic receptor	0	3	1	4
Alpha-1B adrenergic receptor	0	5	0	5
Alpha-2B adrenergic receptor	0	2	0	2
5-hydroxytryptamine receptor 1A	0	4	0	5
Sodium-dependent noradrenaline transporter	0	8	1	9
Thromboxane-A synthase	0	1	0	1
Type-1 angiotensin II receptor	0	2	1	3
Alpha-1A adrenergic receptor	0	5	0	5
10 kDa heat shock protein, mitochondrial	0	2	0	2
Thiosulfate sulfurtransferase	0	2	0	2
60 kDa chaperonin	0	2	0	2
10 kDa chaperonin	0	2	0	2
Leukotriene B4 receptor 2	0	1	1	2
Chain A, angiotensin converting enzyme	0	1	0	1
Chain A, angiotensin converting enzyme	0	1	0	1
15-lipoxygenase, partial	4	0	0	4
Thrombopoietin	3	0	0	3
thioredoxin glutathione reductase	2	0	0	2
Metallo-beta-lactamase type 2	0	1	1	2
peripheral myelin protein 22 isoform 1	8	0	0	8
M-phase phosphoprotein 8	5	0	0	5
transient receptor potential cation channel subfamily V member 1	1	0	0	1
Neprilysin	0	1	0	1
Neprilysin	0	2	0	2
Leukotriene A-4 hydrolase	0	3	1	4
EEF1AKMT4-ECE2 readthrough transcript protein	0	1	0	1
Angiotensin-converting enzyme	0	3	0	4
Leukotriene A-4 hydrolase	0	1	0	1
Thymidine phosphorylase	0	0	1	1
Endothelin-converting enzyme 1	0	1	0	1
Succinyl-diaminopimelate desuccinylase	0	3	0	3
Angiotensin-converting enzyme	0	3	0	3
Solute carrier family 15 member 1	0	2	0	2
Beta-lactamase TEM	0	1	0	1
Mu-type opioid receptor	0	2	1	3
Beta-lactamase	0	2	0	3
Beta-lactamase	0	2	0	2
Angiotensin-converting enzyme 2	0	2	1	3
Beta-lactamase class B VIM-2	0	1	1	2
Chain A, ATP-DEPENDENT DNA HELICASE Q1	2	0	0	2
DNA polymerase eta isoform 1	3	0	0	3
neuropeptide S receptor isoform A	3	0	0	3
Arginase	0	3	0	3
Pancreatic triacylglycerol lipase	0	2	0	2
Carbonic anhydrase 4	0	9	0	11
Carbonic anhydrase 6	0	5	0	7
Sucrase-isomaltase, intestinal	0	2	0	2
Mu-type opioid receptor	0	0	0	1
Delta-type opioid receptor	0	0	0	1
Kappa-type opioid receptor	0	0	0	1
Melatonin receptor type 1A	0	2	2	4
Melatonin receptor type 1B	0	2	2	4
Death-associated protein kinase 1	0	2	0	2
Beta-secretase 1	0	3	0	3
Carbonic anhydrase 3	0	2	0	2
Dihydroorotate dehydrogenase	0	1	0	1
cystic fibrosis transmembrane conductance regulator ATP-binding cassette sub-family C member 7	0	0	0	1
Carbonic anhydrase 12	0	6	0	8
Carbonic anhydrase 3	0	4	0	5
Carbonic anhydrase 5A, mitochondrial	0	5	0	7
Carbonic anhydrase 7	0	5	0	7
Carbonic anhydrase 9	0	6	0	8
Carbonic anhydrase 13	0	3	0	5
Carbonic anhydrase 14	0	4	0	6
Carbonic anhydrase 5B, mitochondrial	0	4	0	6
Luciferase	9	0	0	9
peroxisome proliferator activated receptor gamma	9	0	0	9
vitamin D (1,25- dihydroxyvitamin D3) receptor	4	0	0	4
Vitamin D3 receptor	0	1	1	4
Glycine receptor subunit alpha-1	0	0	1	1
Vitamin D3 receptor	0	0	1	1
N(G),N(G)-dimethylarginine dimethylaminohydrolase 1	0	4	0	6
General amino-acid permease GAP1	0	0	0	1
Chain A, CHIMERA OF IG KAPPA CHAIN: HUMAN CONSTANT REGION AND MOUSE VARIABLE REGION	0	0	1	1
Chain B, CHIMERA OF IG GAMMA-1 CHAIN: HUMAN CONSTANT REGION AND MOUSE VARIABLE REGION	0	0	1	1
Chain H, Fab M82G2, Heavy chain	0	0	1	1
Chain L, Fab M82G2, Light chain	0	0	1	1
Chain H, Fab M82g2, Heavy Chain	0	0	1	1
Chain L, Fab M82g2, Light Chain	0	0	1	1
Gamma-aminobutyric acid receptor subunit pi	0	2	0	2
Gamma-aminobutyric acid receptor subunit delta	0	2	0	2
Amyloid-beta precursor protein	0	3	1	4
Fatty acid-binding protein, heart	0	1	0	1
Muscarinic acetylcholine receptor M2	0	1	0	1
Muscarinic acetylcholine receptor M1	0	2	0	2
5-hydroxytryptamine receptor 2C	0	2	0	2
Tryptophan 5-hydroxylase 1	0	1	0	1
5-hydroxytryptamine receptor 2A	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-1	0	2	1	3
Gamma-aminobutyric acid receptor subunit beta-1	0	2	1	3
Gamma-aminobutyric acid receptor subunit gamma-2	0	2	1	3
D	0	1	0	1
Liver carboxylesterase 1	0	0	0	1
Sodium-dependent dopamine transporter	0	4	0	4
Gamma-aminobutyric acid receptor subunit beta-3	0	2	1	3
5-hydroxytryptamine receptor 1B	0	1	0	1
5-hydroxytryptamine receptor 1D	0	1	0	1
5-hydroxytryptamine receptor 1F	0	1	0	1
5-hydroxytryptamine receptor 2B	0	2	0	2
5-hydroxytryptamine receptor 6	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-5	0	2	1	3
Sodium-dependent serotonin transporter	0	4	0	4
Sodium-dependent serotonin transporter	0	3	0	4
5-hydroxytryptamine receptor 7	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-3	0	2	1	3
5-hydroxytryptamine receptor 5A	0	1	0	1
5-hydroxytryptamine receptor 5B	0	1	0	1
Glutamate receptor ionotropic, NMDA 1	0	1	1	3
5-hydroxytryptamine receptor 3A	0	1	0	1
Lysosomal Pro-X carboxypeptidase	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-2	0	2	1	3
Gamma-aminobutyric acid receptor subunit beta-2	0	2	1	3
Gamma-aminobutyric acid receptor subunit alpha-4	0	2	1	3
D(2) dopamine receptor	0	1	0	1
Gamma-aminobutyric acid receptor subunit epsilon	0	2	0	2
Glutamate receptor ionotropic, NMDA 2A	0	1	1	3
Glutamate receptor ionotropic, NMDA 2B	0	1	1	3
Glutamate receptor ionotropic, NMDA 2C	0	1	1	3
cAMP-specific 3',5'-cyclic phosphodiesterase 4B	0	2	0	3
cAMP-specific 3',5'-cyclic phosphodiesterase 4D	0	2	0	2
Leukotriene B4 receptor 1	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-6	0	2	1	3
Sodium-dependent dopamine transporter	0	2	0	2
Glutamate receptor ionotropic, NMDA 2D	0	1	1	3
5-hydroxytryptamine receptor 4	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-1	0	2	0	2
Glutamate receptor ionotropic, NMDA 3B	0	1	1	3
Gamma-aminobutyric acid receptor subunit gamma-3	0	2	0	2
5-hydroxytryptamine receptor 3B	0	1	0	1
Glutamate receptor ionotropic, NMDA 3A	0	1	1	3
Gamma-aminobutyric acid receptor subunit theta	0	2	0	2
Transporter	0	3	1	5
Phosphodiesterase	0	1	0	1
Multidrug resistance-associated protein 5	0	0	0	1
cGMP-inhibited 3',5'-cyclic phosphodiesterase B	0	2	0	2
cGMP-inhibited 3',5'-cyclic phosphodiesterase A	0	2	0	2
activating transcription factor 6	7	0	0	7
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a	1	0	0	1
heat shock protein beta-1	2	0	0	2
importin subunit beta-1 isoform 1	2	0	0	2
snurportin-1	2	0	0	2
GTP-binding nuclear protein Ran isoform 1	1	0	0	1
Rap guanine nucleotide exchange factor 3	3	0	0	3
Glutathione S-transferase P	0	1	0	1
Alpha-tocopherol transfer protein	0	0	1	1
ATAD5 protein, partial	7	0	0	7
caspase 7, apoptosis-related cysteine protease	4	0	0	4
Neuraminidase	0	3	0	3
67.9K protein	4	0	0	4
Parkin	4	0	0	4
pyruvate kinase	3	0	0	3
caspase-3	4	0	0	4
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)	3	0	0	3
aryl hydrocarbon receptor	10	0	0	10
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a	8	0	0	8
NPC intracellular cholesterol transporter 1 precursor	3	0	0	3
cellular tumor antigen p53 isoform a	4	0	0	4
cytochrome P450 2C9 precursor	3	0	0	3
parathyroid hormone/parathyroid hormone-related peptide receptor precursor	3	0	0	3
histone deacetylase 9 isoform 3	5	0	0	5
urokinase-type plasminogen activator precursor	2	0	0	2
plasminogen precursor	2	0	0	2
urokinase plasminogen activator surface receptor precursor	2	0	0	2
rac GTPase-activating protein 1 isoform a	0	1	0	1
pyruvate kinase PKM isoform b	2	0	0	2
Polyunsaturated fatty acid lipoxygenase ALOX15B	2	2	0	4
Aldo-keto reductase family 1 member B10	0	1	0	1
Transthyretin	0	2	1	4
Estrogen receptor	0	4	0	4
Glucocorticoid receptor	0	0	0	1
Aldehyde dehydrogenase, mitochondrial	0	1	0	1
Ornithine decarboxylase	2	0	0	2
Androgen receptor	0	0	0	1
Tyrosinase	0	4	0	4
Aromatase	0	6	0	6
Urease subunit alpha	0	4	0	4
Aldo-keto reductase family 1 member B1	0	3	0	3
Polyunsaturated fatty acid lipoxygenase ALOX15	0	2	0	2
Polyunsaturated fatty acid lipoxygenase ALOX12	0	2	0	2
UDP-glucuronosyltransferase 1A1	0	3	0	3
UDP-glucuronosyltransferase 1A4	0	0	0	1
Proteasome subunit beta type-5	0	2	0	2
Histamine H2 receptor	4	0	1	5
Estrogen receptor	0	0	1	1
Urease subunit beta	0	4	0	4
Transporter	0	1	0	1
Substance-K receptor	0	2	0	2
Estrogen receptor beta	0	3	0	3
Beta-hydroxyacyl-ACP dehydratase precursor (Fatty acid synthesis protein)	0	2	0	2
ATPase family AAA domain-containing protein 5	2	0	0	2
Ataxin-2	3	0	0	3
Prenyltransferase homolog	0	0	0	2
Estrogen receptor beta	0	0	1	1
Sodium/glucose cotransporter 1	0	1	1	2
Sodium/glucose cotransporter 2	0	1	1	2
Sodium/glucose cotransporter 2	0	0	1	1
Sodium/myo-inositol cotransporter 2	0	1	0	1
Solute carrier family 5 member 4	0	1	0	1
Solute carrier family 22 member 2	0	0	0	1
Thromboxane A2 receptor	0	2	1	4
Prostaglandin E2 receptor EP1 subtype	0	1	1	2
Prostaglandin E2 receptor EP4 subtype	0	1	0	1
Prostaglandin F2-alpha receptor	0	2	0	2
Prostaglandin F2-alpha receptor	0	2	1	3
Prostaglandin E2 receptor EP3 subtype	0	1	1	2
Prostaglandin E2 receptor EP2 subtype	0	1	0	1
Prostaglandin F2-alpha receptor	0	0	1	1
Prostacyclin receptor	0	1	0	1
Prostaglandin D2 receptor	0	1	0	1
Solute carrier family 22 member 6	0	2	0	4
Solute carrier family 22 member 7	0	1	0	2
Solute carrier family 22 member 8	0	3	0	4
Solute carrier organic anion transporter family member 2A1	0	1	0	2
Solute carrier organic anion transporter family member 2A1	0	1	0	1
Solute carrier organic anion transporter family member 2B1	0	1	0	1
Solute carrier family 22 member 11	0	2	0	3
Solute carrier family 22 member 7	0	2	0	3
Chain A, Protein (peroxisome Proliferator Activated Receptor (ppar-delta))	0	1	0	1
histone-lysine N-methyltransferase 2A isoform 2 precursor	4	0	0	4
Trypsin	0	1	0	1
Cytochrome P450 1A2	0	5	0	5
Coagulation factor VII	0	1	0	1
Tissue factor	0	1	0	1
Retinoic acid receptor RXR-alpha	0	1	2	3
Peroxisome proliferator-activated receptor gamma	0	0	3	3
Oxoeicosanoid receptor 1	0	1	0	1
endonuclease IV	1	0	0	1
Solute carrier family 15 member 1	0	2	0	2
Multidrug and toxin extrusion protein 1	0	2	0	2
Chain A, Dihydrofolate reductase	0	0	1	1
glp-1 receptor, partial	3	0	0	3
Thymidylate synthase	0	2	0	2
Thymidylate synthase	0	1	0	1
Dihydrofolate reductase	0	0	1	1
Alpha-synuclein	2	1	0	3
Folylpolyglutamate synthase, mitochondrial	0	0	0	1
Solute carrier organic anion transporter family member 1A3	0	1	0	2
Folylpolyglutamate synthase, mitochondrial	0	0	0	1
Multidrug resistance associated protein	0	0	0	1
Gamma-aminobutyric acid	0	0	1	1
Gamma-aminobutyric acid receptor subunit rho-3	0	0	1	1
Hsf1 protein	0	0	2	2
bromodomain adjacent to zinc finger domain 2B	3	0	0	3
D(1A) dopamine receptor	3	0	0	3
Histone deacetylase 3	0	1	0	1
Gamma-aminobutyric acid type B receptor subunit 2	0	0	1	1
Gamma-aminobutyric acid type B receptor subunit 2	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-6	0	0	1	1
Gamma-aminobutyric acid receptor subunit gamma-2	0	0	1	1
Gamma-aminobutyric acid receptor subunit delta	0	0	1	1
Sodium- and chloride-dependent GABA transporter 1	0	2	0	2
Gamma-aminobutyric acid receptor subunit rho-1	0	0	2	2
Gamma-aminobutyric acid receptor subunit alpha-2	0	0	1	1
Gamma-aminobutyric acid receptor subunit alpha-3	0	0	1	1
Gamma-aminobutyric acid receptor subunit gamma-3	0	0	1	1
Gamma-aminobutyric acid receptor subunit rho-2	0	0	1	1
Sodium- and chloride-dependent GABA transporter 1	0	1	0	1
Sodium- and chloride-dependent taurine transporter	0	2	0	2
Sodium- and chloride-dependent GABA transporter 2	0	2	0	2
Sodium- and chloride-dependent GABA transporter 3	0	2	0	2
Sodium- and chloride-dependent GABA transporter 1	0	1	0	1
Sodium- and chloride-dependent GABA transporter 2	0	1	0	1
Sodium- and chloride-dependent GABA transporter 3	0	1	0	1
Sodium- and chloride-dependent betaine transporter	0	2	0	2
Sodium- and chloride-dependent betaine transporter	0	1	0	1
Sodium- and chloride-dependent GABA transporter 3	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-1	0	0	1	1
Histone deacetylase 4	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-1	0	0	1	1
Gamma-aminobutyric acid receptor subunit beta-3	0	0	1	1
4-aminobutyrate aminotransferase, mitochondrial	0	0	0	1
4-aminobutyrate aminotransferase, mitochondrial	0	0	0	1
Histone deacetylase 1	0	1	0	1
Sterol O-acyltransferase 1	0	0	1	1
Proton-coupled amino acid transporter 1	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-5	0	0	1	1
Gamma-aminobutyric acid receptor subunit pi	0	0	1	1
Histone deacetylase 7	0	1	0	1
Histone deacetylase 2	0	1	0	1
Polyamine deacetylase HDAC10	0	1	0	1
Histone deacetylase 11	0	1	0	1
Histone deacetylase 8	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-4	0	0	1	1
Platelet glycoprotein VI	0	1	2	4
Gamma-aminobutyric acid receptor subunit theta	0	0	1	1
Sodium- and chloride-dependent GABA transporter 2	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-1	0	0	1	1
Histone deacetylase 6	0	1	0	1
Gamma-aminobutyric acid type B receptor subunit 1	0	0	1	1
Histone deacetylase 9	0	1	0	1
Histone deacetylase 5	0	1	0	1
Gamma-aminobutyric acid type B receptor subunit 1	0	1	0	1
Glucagon-like peptide 1 receptor	0	0	1	1
Glucagon-like peptide 1 receptor	0	1	1	2
Glucagon receptor	0	0	1	1
Glucagon receptor	0	0	1	1
Asialoglycoprotein receptor 1	0	1	1	2
N-glycosylase/DNA lyase	0	1	0	1
Polyunsaturated fatty acid lipoxygenase ALOX15	0	3	0	3
Aspartate aminotransferase, cytoplasmic	0	1	0	1
Lactoperoxidase	0	2	0	2
Single-stranded DNA cytosine deaminase	1	0	0	1
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase	0	1	0	1
Albumin	0	1	0	1
Delta-type opioid receptor	0	2	0	2
Delta-type opioid receptor	0	2	0	2
Mu-type opioid receptor	0	3	0	3
Cytochrome P450 2J2	0	1	0	1
Carbonic anhydrase, alpha family	0	1	0	1
Carbonic anhydrase	0	1	0	1
Delta carbonic anhydrase	0	1	0	1
hypoxia-inducible factor 1 alpha subunit	2	0	0	2
NPYLR7B	0	0	1	1
Beta-1 adrenergic receptor	0	0	1	2
Histone H2A.x	5	0	0	5
beta-2 adrenergic receptor	1	0	0	1
hexokinase-4 isoform 1	2	0	0	2
glucokinase regulatory protein	2	0	0	2
serine/threonine-protein kinase mTOR isoform 1	2	0	0	2
Bile salt export pump	0	2	0	2
Beta-2 adrenergic receptor	0	2	2	5
Beta-1 adrenergic receptor	0	2	1	3
Beta-2 adrenergic receptor	0	2	1	3
D(2) dopamine receptor	0	1	0	1
Beta-1 adrenergic receptor	0	2	1	4
Beta-2 adrenergic receptor	0	0	1	1
D(1A) dopamine receptor	0	1	0	1
D(4) dopamine receptor	0	2	0	2
Alpha-1D adrenergic receptor	0	2	0	2
Beta-adrenergic receptor kinase 1	0	0	2	2
Beta-3 adrenergic receptor	0	0	1	1
Beta-3 adrenergic receptor	0	1	1	2
Beta-1 adrenergic receptor	0	1	1	2
D(3) dopamine receptor	0	1	0	1
D(1A) dopamine receptor	2	0	0	2
Beta-2 adrenergic receptor	0	1	0	1
Taste receptor type 2 member 38	0	0	1	1
Taste receptor type 2 member 39	0	0	1	1
Taste receptor type 2 member 40	0	0	1	1
Taste receptor type 2 member 41	0	0	1	1
Taste receptor type 2 member 43	0	0	1	1
Taste receptor type 2 member 31	0	0	2	2
Taste receptor type 2 member 45	0	0	1	1
Taste receptor type 2 member 46	0	0	1	1
Taste receptor type 2 member 30	0	0	1	1
Taste receptor type 2 member 19	0	0	1	1
Taste receptor type 2 member 20	0	0	1	1
Taste receptor type 2 member 50	0	0	1	1
Taste receptor type 2 member 60	0	0	2	2
Beta-2 adrenergic receptor	0	1	1	2
Taste receptor type 2 member 42	0	0	1	1
Beta-2 adrenergic receptor	0	0	2	2
Taste receptor type 2 member 16	0	0	1	1
Taste receptor type 2 member 14	0	0	2	2
Taste receptor type 2 member 13	0	0	2	2
Taste receptor type 2 member 10	0	0	1	1
Taste receptor type 2 member 9	0	0	2	2
Taste receptor type 2 member 8	0	0	1	1
Taste receptor type 2 member 7	0	0	1	1
Taste receptor type 2 member 5	0	0	1	1
Taste receptor type 2 member 4	0	0	2	2
Taste receptor type 2 member 3	0	0	1	1
Taste receptor type 2 member 1	0	0	1	1
2,3-bisphosphoglycerate-independent phosphoglycerate mutase	1	0	0	1
Chain A, Beta-lactamase	2	0	0	2
Squalene synthase	0	2	0	2
cAMP-specific 3',5'-cyclic phosphodiesterase 4C	0	1	0	1
Type-1 angiotensin II receptor	0	1	1	2
ClpP	2	0	0	2
Cytochrome P450 1A1	0	4	1	5
Cytochrome P450 1A2	0	1	0	1
Cytochrome P450 2C11	0	1	0	1
Cytochrome P450 2D6	0	2	0	2
Ribosyldihydronicotinamide dehydrogenase [quinone]	0	4	2	6
Metabotropic glutamate receptor 1	0	1	0	1
Acetylcholinesterase	0	1	0	1
Nociceptin receptor	0	1	0	1
Melatonin receptor type 1C	0	0	1	1
Melatonin receptor type 1A	0	1	1	2
Melatonin receptor type 1C	0	1	1	2
Melatonin receptor type 1B	0	1	1	2
Nuclear factor erythroid 2-related factor 2	0	0	1	3
Carboxylic ester hydrolase	0	1	0	1
Histamine H3 receptor	0	1	0	1
Sialidase-4	0	1	0	1
Sialidase-1	0	1	0	1
Sialidase-3	0	1	0	1
Sialidase-2	0	2	0	2
N(G),N(G)-dimethylarginine dimethylaminohydrolase 1	0	0	0	2
N(G),N(G)-dimethylarginine dimethylaminohydrolase 1	0	0	0	1
Atrial natriuretic peptide receptor 1	0	1	0	1
Neuropeptide Y receptor type 1	0	2	0	2
Neuropeptide Y receptor type 2	0	2	0	2
5-hydroxytryptamine receptor 3E	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-4	0	2	1	3
Transient receptor potential cation channel subfamily A member 1	0	1	3	4
5-hydroxytryptamine receptor 3B	0	1	0	1
Acetylcholine receptor subunit alpha	0	2	1	3
Acetylcholine receptor subunit alpha	0	2	1	3
Acetylcholine receptor subunit beta	0	2	1	3
Acetylcholine receptor subunit gamma	0	2	1	3
Acetylcholine receptor subunit delta	0	2	1	3
Neuronal acetylcholine receptor subunit alpha-3	0	2	2	5
Acetylcholine receptor subunit gamma	0	2	1	3
Muscarinic acetylcholine receptor M3	0	1	0	1
Muscarinic acetylcholine receptor M4	0	2	0	2
Muscarinic acetylcholine receptor M5	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-4	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-4	0	3	2	6
Muscarinic acetylcholine receptor M2	0	1	0	1
Acetylcholine receptor subunit beta	0	2	1	3
Cytochrome P450 2A6	0	2	1	3
Neuronal acetylcholine receptor subunit alpha-2	0	2	2	5
Neuronal acetylcholine receptor subunit beta-2	0	3	2	6
Neuronal acetylcholine receptor subunit beta-3	0	2	2	5
Neuronal acetylcholine receptor subunit beta-4	0	2	2	5
Neuronal acetylcholine receptor subunit beta-2	0	2	1	3
Neuronal acetylcholine receptor subunit alpha-5	0	2	2	5
Cytochrome P450 2A5	0	1	0	1
Acetylcholine receptor subunit beta-like 2	0	2	0	2
Neuronal acetylcholine receptor subunit alpha-5	0	0	1	1
Neuronal acetylcholine receptor subunit beta-4	0	2	1	3
Muscarinic acetylcholine receptor M4	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-3	0	2	1	3
Neuronal acetylcholine receptor subunit alpha-7	0	2	2	4
Neuronal acetylcholine receptor subunit alpha-6	0	2	2	5
Neuronal acetylcholine receptor subunit alpha-9	0	2	2	5
Neuronal acetylcholine receptor subunit alpha-4	0	2	1	3
5-hydroxytryptamine receptor 3A	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-7	0	2	0	2
Acetylcholine-binding protein	0	1	1	2
Acetylcholine receptor subunit epsilon	0	0	1	1
Neuronal acetylcholine receptor subunit beta-3	0	1	1	2
Neuronal acetylcholine receptor subunit alpha-7	0	2	2	5
Acetylcholine receptor subunit delta	0	2	1	3
Neuronal acetylcholine receptor subunit alpha-2	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-6	0	1	1	2
Cytochrome P450 2A13	0	1	1	2
Neuronal acetylcholine receptor subunit alpha-5	0	2	0	2
Liver carboxylesterase B-1	0	1	0	1
5-hydroxytryptamine receptor 3D	0	1	0	1
Transient receptor potential cation channel subfamily A member 1	0	0	1	1
Neuronal acetylcholine receptor subunit beta-3	0	2	0	2
Neuronal acetylcholine receptor subunit beta-4	0	2	0	2
Neuronal acetylcholine receptor subunit alpha-3	0	2	0	2
Soluble acetylcholine receptor	0	1	0	1
5-hydroxytryptamine receptor 3C	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-2	0	2	0	2
Neuronal acetylcholine receptor subunit beta-2	0	2	1	3
Neuronal acetylcholine receptor subunit alpha-10	0	2	2	5
Neuronal acetylcholine receptor subunit alpha-6	0	2	0	2
Integrin beta	0	0	1	1
Glycoprotein IIb	0	0	1	1
Carbonic anhydrase	0	2	0	3
Sodium/iodide cotransporter	0	1	0	1
Carbonic anhydrase 15	0	3	0	4
Neutrophil elastase	0	3	0	3
Proteinase-activated receptor 1	0	1	0	1
Nitric oxide synthase, endothelial	0	2	0	2
Collagenase 3	0	2	0	2
Nitric oxide synthase, brain	0	1	0	1
Tyrosine-protein kinase Lck	0	2	2	4
Sodium/potassium/calcium exchanger 4	0	1	1	2
Sodium/potassium/calcium exchanger 2	0	1	1	2
UDP-glucuronosyltransferase 1A9	0	1	0	1
Solute carrier family 22 member 8	0	1	0	1
UDP-glucuronosyltransferase 1-6	0	1	0	1
Pannexin-1	0	1	0	1
Solute carrier family 22 member 12	0	1	0	1
Solute carrier organic anion transporter family member 1C1	0	1	0	1
UDP-glucuronosyltransferase 1A7	0	1	0	1
UDP-glucuronosyltransferase 1A10	0	1	0	1
Pannexin-1	0	1	0	1
Solute carrier family 22 member 8	0	2	0	2
Chain A, (3R)-hydroxymyristoyl-acyl carrier protein dehydratase	0	1	0	1
Chain B, (3R)-hydroxymyristoyl-acyl carrier protein dehydratase	0	1	0	1
Chain A, (3R)-hydroxymyristoyl-acyl carrier protein dehydratase	0	1	0	1
Chain B, (3R)-hydroxymyristoyl-acyl carrier protein dehydratase	0	1	0	1
Chain A, (3R)-hydroxymyristoyl-acyl carrier protein dehydratase	0	1	0	1
Chain B, (3R)-hydroxymyristoyl-acyl carrier protein dehydratase	0	1	0	1
Chain A, APH(2')-Id	0	1	0	1
glucose-6-phosphate dehydrogenase	0	1	0	1
Nrf2	1	0	0	1
SMAD family member 2	2	0	0	2
SMAD family member 3	2	0	0	2
signal transducer and activator of transcription 6, interleukin-4 induced	1	0	0	1
DNA polymerase III, partial	1	0	0	1
hexokinase	0	1	0	1
Spike glycoprotein	0	0	1	1
Replicase polyprotein 1ab	0	0	1	1
galactokinase	1	0	0	1
interferon gamma precursor	0	0	0	1
polyunsaturated fatty acid lipoxygenase ALOX12	1	0	0	1
mitogen-activated protein kinase 1	1	0	0	1
ubiquitin carboxyl-terminal hydrolase 2 isoform a	1	0	0	1
tyrosine-protein kinase Yes	1	0	0	1
peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	2	0	0	2
muscleblind-like protein 1 isoform 1	2	0	0	2
Transmembrane protease serine 2	0	0	1	1
Maltase-glucoamylase, intestinal	0	1	0	1
NUAK family SNF1-like kinase 1	0	1	0	1
B2 bradykinin receptor	0	1	0	1
G2/mitotic-specific cyclin-B2	0	1	0	1
Glutathione reductase, mitochondrial	0	1	0	1
Prothrombin	0	1	0	1
Chymotrypsinogen A	0	1	0	1
Chymotrypsin-like elastase family member 1	0	1	0	1
Beta-lactamase	0	1	0	1
Protein E6	0	1	0	1
Interstitial collagenase	0	1	1	2
Phospholipase A2	0	1	0	1
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1	0	2	0	2
Beta-lactamase	0	1	0	1
Cyclin-dependent kinase 1	0	1	1	2
Glycogen phosphorylase, liver form	0	1	1	2
Epoxide hydrolase 1	0	1	0	1
Procathepsin L	0	0	1	1
Tyrosine-protein kinase Yes	0	1	1	2
Proto-oncogene tyrosine-protein kinase receptor Ret	0	1	1	2
Insulin-like growth factor 1 receptor	0	1	1	2
72 kDa type IV collagenase	0	1	0	1
Stromelysin-1	0	2	0	2
Hepatocyte growth factor receptor	0	1	1	2
5-hydroxytryptamine receptor 1A	0	0	1	1
Heterogeneous nuclear ribonucleoprotein A1	0	0	1	1
Polyunsaturated fatty acid 5-lipoxygenase	0	2	0	2
Enoyl-[acyl-carrier-protein] reductase [NADH] FabI	0	1	0	1
Replicase polyprotein 1a	0	0	1	1
Replicase polyprotein 1ab	0	0	1	1
Calmodulin-1	0	1	0	1
Alpha-amylase 1A	0	1	0	1
Lysosomal alpha-glucosidase	0	1	0	1
Sialidase	0	1	0	1
Malate dehydrogenase	0	1	0	1
Cytochrome P450 2C8	0	1	0	1
Solute carrier family 2, facilitated glucose transporter member 2	0	1	0	1
Serine/threonine-protein kinase pim-1	0	1	2	3
Cyclin-dependent kinase 4	0	1	1	2
Polyunsaturated fatty acid 5-lipoxygenase	0	1	0	1
Proto-oncogene tyrosine-protein kinase Src	0	1	1	2
Cystic fibrosis transmembrane conductance regulator	0	0	1	1
Sucrase-isomaltase, intestinal	0	1	0	1
G2/mitotic-specific cyclin-B1	0	1	0	1
Tyrosinase	0	2	0	2
Matrix metalloproteinase-9	0	1	0	1
Serine/threonine-protein kinase B-raf	0	1	1	2
G2/mitotic-specific cyclin-B	0	1	0	1
Cytochrome P450 11B1, mitochondrial	0	1	0	1
Aldo-keto reductase family 1 member B1	0	1	0	1
Chymotrypsinogen B	0	1	0	1
Glycogen synthase kinase-3 beta	0	1	0	1
Solute carrier family 2, facilitated glucose transporter member 4	0	1	0	1
Casein kinase II subunit alpha'	0	2	1	3
Amine oxidase [flavin-containing] A	0	1	0	1
5'-nucleotidase	0	1	0	1
Glyceraldehyde-3-phosphate dehydrogenase, glycosomal	0	1	0	1
G1/S-specific cyclin-D1	0	1	0	1
Cyclin-dependent kinase 2	0	1	1	2
C-X-C chemokine receptor type 1	0	1	0	1
Dipeptidyl peptidase 4	0	2	0	2
Phosphatidylinositol 3-kinase regulatory subunit alpha	0	1	0	1
Cytosol aminopeptidase	0	1	0	1
ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1	0	2	0	2
Tyrosine-protein kinase receptor UFO	0	1	0	1
RAC-alpha serine/threonine-protein kinase	0	1	1	2
Multidrug resistance-associated protein 1	0	1	0	1
Bifunctional epoxide hydrolase 2	0	1	0	1
Prostaglandin G/H synthase 2	0	1	0	1
Vascular endothelial growth factor receptor 2	0	1	0	1
Receptor-type tyrosine-protein kinase FLT3	0	1	1	2
17-beta-hydroxysteroid dehydrogenase type 2	0	1	0	1
Macrophage metalloelastase	0	1	0	1
Kappa-type opioid receptor	0	1	0	1
Glutathione reductase	0	1	0	1
Tyrosine-protein kinase SYK	0	1	2	3
1-deoxy-D-xylulose 5-phosphate reductoisomerase	0	1	0	1
Glycogen synthase kinase-3 alpha	0	1	1	2
Glycogen synthase kinase-3 beta	0	1	1	2
Aldo-keto reductase family 1 member A1	0	1	0	1
Aldo-keto reductase family 1 member A1	0	1	0	1
C-C chemokine receptor type 4	0	1	0	1
Serine/threonine-protein kinase Nek2	0	1	1	2
Oligo-1,6-glucosidase IMA1	0	1	0	1
Serine/threonine-protein kinase PLK1	0	1	1	2
Mitogen-activated protein kinase 10	0	1	1	2
Monocarboxylate transporter 1	0	1	0	1
Amine oxidase [flavin-containing] B	0	1	0	1
Anthrax toxin receptor 2	0	1	0	1
Casein kinase II subunit beta	0	2	0	2
Casein kinase II subunit alpha	0	2	0	2
Disintegrin and metalloproteinase domain-containing protein 17	1	0	0	1
Aldo-keto reductase family 1 member B1	0	1	0	1
Cyclin-dependent kinase 6	0	1	1	2
Cyclin-dependent-like kinase 5	0	1	1	2
Heat shock factor protein 1	0	1	0	1
Sorbitol dehydrogenase	0	1	0	1
Cyclin homolog	0	1	0	1
cGMP-dependent 3',5'-cyclic phosphodiesterase	0	1	0	1
Dual specificity mitogen-activated protein kinase kinase 1	0	1	1	2
Lactoylglutathione lyase	0	2	0	2
Focal adhesion kinase 1	0	1	1	2
Calcium/calmodulin-dependent protein kinase type II subunit beta	0	1	0	1
ELAV-like protein 3	0	1	0	1
Cyclin-dependent kinase 5 activator 1	0	1	0	1
ELAV-like protein 1	0	1	0	1
Serine/threonine-protein kinase N1	0	1	1	2
Mitogen-activated protein kinase 14	0	1	1	2
Probable maltase-glucoamylase 2	0	1	0	1
Monocarboxylate transporter 2	0	1	0	1
Prostaglandin G/H synthase 1	0	1	0	1
Integrase	0	1	0	1
Casein kinase II subunit alpha 3	0	2	0	2
Inositol polyphosphate multikinase	0	1	0	1
G2/mitotic-specific cyclin-B3	0	1	0	1
Aldo-keto reductase family 1 member C21	0	2	0	2
Enoyl-acyl-carrier protein reductase	0	2	0	2
3-oxoacyl-acyl-carrier protein reductase	0	1	0	1
Aurora kinase B	0	1	1	2
Chymotrypsin-C	0	1	0	1
Cyclin-dependent kinase 1	0	1	0	1
G-protein coupled receptor 35	0	1	1	2
Serine/threonine-protein kinase Nek6	0	1	0	1
NADPH oxidase 4	0	1	0	1
Hypoxia-inducible factor 1-alpha inhibitor	0	1	0	1
Dipeptidyl peptidase 3	0	1	0	1
Inositol hexakisphosphate kinase 2	0	1	0	1
Short transient receptor potential channel 5	0	1	0	1
ALK tyrosine kinase receptor	0	1	0	1
phosphoglycerate kinase	1	0	0	1
Chain A, Troponin C, slow skeletal and cardiac muscles	0	0	1	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
BRCA1	1	0	0	1
P53	1	0	0	1
M18 aspartyl aminopeptidase	0	1	0	1
cathepsin L1	0	1	0	1
atrial natriuretic peptide receptor 2 precursor	1	0	0	1
nuclear factor NF-kappa-B p105 subunit isoform 1	0	0	1	1
FAD-linked sulfhydryl oxidase ALR	0	0	0	1
Vif	0	1	0	1
DNA dC->dU-editing enzyme APOBEC-3G isoform 1	0	1	0	1
transcription factor p65 isoform 1	0	0	1	1
serine/threonine-protein kinase 33 isoform a	0	0	1	1
POsterior Segregation	0	0	1	1
Aryl hydrocarbon receptor	0	1	0	1
Estrogen receptor beta	0	0	1	1
Tyrosine-protein kinase ABL1	0	1	1	3
Myc proto-oncogene protein	0	1	0	2
Cathepsin D	0	1	0	1
Luciferin 4-monooxygenase	0	1	0	1
DNA polymerase alpha catalytic subunit	0	1	0	1
Breakpoint cluster region protein	0	1	1	3
Ornithine decarboxylase	0	1	0	1
Protein kinase C alpha type	0	0	2	2
Estrogen receptor	0	0	1	1
Nuclear factor NF-kappa-B p105 subunit	0	1	0	1
Endothelin receptor type B	1	0	0	1
Cytochrome P450 2C19	0	2	0	2
Cannabinoid receptor 1	0	1	0	1
Alpha-glucosidase MAL12	0	1	0	1
Nuclear factor NF-kappa-B p100 subunit	0	1	0	1
Transcription factor p65	0	1	0	1
Bcl-2-like protein 1	0	1	0	1
Serine/threonine-protein kinase PAK 1	0	1	0	1
N1L	0	1	0	1
NAD(P)H dehydrogenase [quinone] 1	0	0	0	3
Tubulin beta-2B chain	0	1	0	1
Lysosomal alpha-glucosidase	0	1	0	1
Transient receptor potential cation channel subfamily A member 1	0	1	0	1
Similar to alpha-tubulin isoform 1	0	1	0	1
Similar to alpha-tubulin isoform 1	0	1	0	1
NAD-dependent protein deacetylase sirtuin-2	0	0	1	1
Carbonic anhydrase 13	0	1	0	1
Rap guanine nucleotide exchange factor 4	1	0	0	1
NAD-dependent protein deacetylase sirtuin-1	0	0	1	3
NAD-dependent protein deacetylase sirtuin-3, mitochondrial	0	0	1	1
Zinc finger protein mex-5	0	0	1	1
large T antigen	0	1	0	1
Bone morphogenetic protein receptor type-1B	0	0	1	1
Cell division cycle 7-related protein kinase	0	0	1	1
Serine/threonine-protein kinase PLK4	0	0	1	1
ATP-dependent RNA helicase DDX3X	0	0	1	1
Pyridoxal kinase	0	0	1	1
Citron Rho-interacting kinase	0	0	1	1
Serine/threonine-protein kinase Chk1	0	0	1	1
Aurora kinase A	0	0	1	1
Cyclin-G-associated kinase	0	0	1	1
Ephrin type-B receptor 6	0	0	1	1
Peroxisomal acyl-coenzyme A oxidase 3	0	0	1	1
Receptor-interacting serine/threonine-protein kinase 2	0	0	1	1
Mitotic checkpoint serine/threonine-protein kinase BUB1	0	0	1	1
Dynamin-like 120 kDa protein, mitochondrial	0	0	1	1
Tyrosine-protein kinase JAK2	0	0	1	1
Eukaryotic translation initiation factor 5B	0	0	1	1
Rho-associated protein kinase 2	0	0	1	1
Serine/threonine-protein kinase ULK1	0	0	1	1
Serine/threonine-protein kinase/endoribonuclease IRE1	0	0	1	1
Nuclear receptor subfamily 1 group I member 2	0	0	2	2
Ribosomal protein S6 kinase alpha-5	0	0	1	1
U5 small nuclear ribonucleoprotein 200 kDa helicase	0	0	1	1
Ribosomal protein S6 kinase alpha-4	0	0	1	1
Serine/threonine-protein kinase 16	0	0	1	1
Cyclin-dependent kinase-like 5	0	0	1	1
Serine/threonine-protein kinase 10	0	0	1	1
Serine/threonine-protein kinase D3	0	0	1	1
Structural maintenance of chromosomes protein 2	0	0	1	1
Mitogen-activated protein kinase kinase kinase 6	0	0	1	1
Mitogen-activated protein kinase kinase kinase kinase 4	0	0	1	1
Serine/threonine-protein kinase LATS1	0	0	1	1
Serine/threonine-protein kinase PAK 4	0	0	1	1
High affinity nerve growth factor receptor	0	0	1	1
ADP/ATP translocase 2	0	0	1	1
Protein kinase C beta type	0	0	1	1
Insulin receptor	0	0	1	1
Tyrosine-protein kinase Fyn	0	0	1	1
Eukaryotic translation initiation factor 4E	0	0	1	1
Tyrosine-protein kinase Fes/Fps	0	0	1	1
Adenine phosphoribosyltransferase	0	0	1	1
Tyrosine-protein kinase Lyn	0	0	1	1
Signal recognition particle receptor subunit alpha	0	0	1	1
Cytochrome c1, heme protein, mitochondrial	0	0	1	1
Tyrosine-protein kinase HCK	0	0	1	1
Platelet-derived growth factor receptor beta	0	0	1	1
Tyrosine-protein kinase Fgr	0	0	1	1
Serine/threonine-protein kinase A-Raf	0	0	1	1
Glycogen phosphorylase, brain form	0	0	1	1
Fibroblast growth factor receptor 1	0	0	1	1
DNA topoisomerase 2-alpha	0	0	1	1
ADP/ATP translocase 3	0	0	1	1
Inosine-5'-monophosphate dehydrogenase 2	0	0	1	1
cAMP-dependent protein kinase type II-alpha regulatory subunit	0	0	1	1
Phosphorylase b kinase gamma catalytic chain, liver/testis isoform	0	0	1	1
Tyrosine-protein kinase Fer	0	0	1	1
cAMP-dependent protein kinase catalytic subunit alpha	0	0	1	1
General transcription and DNA repair factor IIH helicase subunit XPD	0	0	1	1
Ras-related protein Rab-6A	0	0	1	1
Ephrin type-A receptor 1	0	0	1	1
Multifunctional protein ADE2	0	0	1	1
cAMP-dependent protein kinase catalytic subunit beta	0	0	1	1
Ferrochelatase, mitochondrial	0	0	1	1
Ribosomal protein S6 kinase beta-1	0	0	1	1
Tyrosine-protein kinase JAK1	0	0	1	1
Probable ATP-dependent RNA helicase DDX6	0	0	1	1
Peptidyl-prolyl cis-trans isomerase FKBP1A	0	1	0	1
Mitogen-activated protein kinase 3	0	0	1	1
MAP/microtubule affinity-regulating kinase 3	0	0	1	1
Deoxycytidine kinase	0	0	1	1
Mitogen-activated protein kinase 1	0	0	1	1
Ephrin type-A receptor 2	0	0	1	1
Ephrin type-B receptor 2	0	0	1	1
Non-receptor tyrosine-protein kinase TYK2	0	0	1	1
UMP-CMP kinase	0	0	1	1
Phosphatidylethanolamine-binding protein 1	0	0	1	1
Wee1-like protein kinase	0	0	1	1
Heme oxygenase 2	0	0	1	1
S-adenosylmethionine synthase isoform type-2	0	0	1	1
DnaJ homolog subfamily A member 1	0	0	1	1
RAC-beta serine/threonine-protein kinase	0	0	1	1
Dual specificity protein kinase TTK	0	0	1	1
DNA replication licensing factor MCM4	0	0	1	1
Myosin-10	0	0	1	1
Dual specificity mitogen-activated protein kinase kinase 2	0	0	1	1
Bone morphogenetic protein receptor type-1A	0	0	1	1
Activin receptor type-1B	0	0	1	1
TGF-beta receptor type-1	0	0	1	1
Serine/threonine-protein kinase receptor R3	0	0	1	1
TGF-beta receptor type-2	0	0	1	1
Electron transfer flavoprotein subunit beta	0	0	1	1
Tyrosine-protein kinase CSK	0	0	1	1
Glycine--tRNA ligase	0	0	1	1
Protein kinase C iota type	0	0	1	1
Exosome RNA helicase MTR4	0	0	1	1
Tyrosine-protein kinase Tec	0	0	1	1
Tyrosine-protein kinase ABL2	0	0	1	1
Tyrosine-protein kinase FRK	0	0	1	1
G protein-coupled receptor kinase 6	0	0	1	1
26S proteasome regulatory subunit 6B	0	0	1	1
Mitogen-activated protein kinase 8	0	0	1	1
Mitogen-activated protein kinase 9	0	0	1	1
Dual specificity mitogen-activated protein kinase kinase 3	0	0	1	1
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha	0	0	1	1
Casein kinase I isoform alpha	0	0	1	1
Casein kinase I isoform delta	0	0	1	1
MAP kinase-activated protein kinase 2	0	0	1	1
Elongation factor Tu, mitochondrial	0	0	1	1
Choline-phosphate cytidylyltransferase A	0	0	1	1
Cysteine--tRNA ligase, cytoplasmic	0	0	1	1
Casein kinase I isoform epsilon	0	0	1	1
Very long-chain specific acyl-CoA dehydrogenase, mitochondrial	0	0	1	1
Dual specificity protein kinase CLK1	0	0	1	1
Dual specificity protein kinase CLK2	0	0	1	1
Dual specificity protein kinase CLK3	0	0	1	1
Cyclin-dependent kinase 7	0	0	1	1
Cyclin-dependent kinase 9	0	0	1	1
Ras-related protein Rab-27A	0	0	1	1
Interleukin-1 receptor-associated kinase 1	0	0	1	1
Ribosomal protein S6 kinase alpha-3	0	0	1	1
Serine/threonine-protein kinase Nek3	0	0	1	1
Dual specificity mitogen-activated protein kinase kinase 6	0	0	1	1
LIM domain kinase 1	0	0	1	1
LIM domain kinase 2	0	0	1	1
Tyrosine--tRNA ligase, cytoplasmic	0	0	1	1
5'-AMP-activated protein kinase subunit gamma-1	0	0	1	1
Ephrin type-B receptor 3	0	0	1	1
Ephrin type-A receptor 5	0	0	1	1
Ephrin type-B receptor 4	0	0	1	1
Ephrin type-A receptor 4	0	0	1	1
Adenylate kinase 2, mitochondrial	0	0	1	1
Adenosine kinase	0	0	1	1
Ras-related protein Rab-10	0	0	1	1
Actin-related protein 3	0	0	1	1
Actin-related protein 2	0	0	1	1
GTP-binding nuclear protein Ran	0	0	1	1
Peptidyl-prolyl cis-trans isomerase FKBP1A	0	2	1	3
Peptidyl-prolyl cis-trans isomerase FKBP1B	0	0	1	1
Casein kinase I isoform gamma-2	0	0	1	1
Cyclin-dependent kinase 16	0	0	1	1
Cyclin-dependent kinase 17	0	0	1	1
ATP-dependent 6-phosphofructokinase, platelet type	0	0	1	1
DNA topoisomerase 2-beta	0	0	1	1
Protein kinase C theta type	0	0	1	1
Activin receptor type-1	0	0	1	1
Macrophage-stimulating protein receptor	0	0	1	1
Protein kinase C zeta type	0	0	1	1
Protein kinase C delta type	0	0	1	1
Tyrosine-protein kinase BTK	0	0	1	1
Cyclin-dependent kinase 18	0	0	1	1
Activated CDC42 kinase 1	0	0	1	1
Epithelial discoidin domain-containing receptor 1	0	0	1	1
Mitogen-activated protein kinase kinase kinase kinase 2	0	0	1	1
Tyrosine-protein kinase Mer	0	0	1	1
Serine/threonine-protein kinase 4	0	0	1	1
5'-AMP-activated protein kinase catalytic subunit alpha-1	0	0	1	1
Dual specificity mitogen-activated protein kinase kinase 5	0	0	1	1
Mitogen-activated protein kinase 7	0	0	1	1
Serine/threonine-protein kinase PAK 2	0	0	1	1
Serine/threonine-protein kinase 3	0	0	1	1
Mitogen-activated protein kinase kinase kinase 1	0	0	1	1
Integrin-linked protein kinase	0	0	1	1
Peptidyl-prolyl cis-trans isomerase FKBP5	0	1	0	1
Rho-associated protein kinase 1	0	0	1	1
Non-receptor tyrosine-protein kinase TNK1	0	0	1	1
Calcium/calmodulin-dependent protein kinase type II subunit gamma	0	0	1	1
Calcium/calmodulin-dependent protein kinase type II subunit delta	0	0	1	1
Dual specificity tyrosine-phosphorylation-regulated kinase 1A	0	0	1	1
Activin receptor type-2B	0	0	1	1
Bone morphogenetic protein receptor type-2	0	0	1	1
Protein-tyrosine kinase 6	0	0	1	1
cGMP-dependent protein kinase 1	0	0	1	1
Cyclin-dependent kinase 13	0	0	1	1
Inhibitor of nuclear factor kappa-B kinase subunit epsilon	0	0	1	1
Protein-tyrosine kinase 2-beta	0	0	1	1
Maternal embryonic leucine zipper kinase	0	0	1	1
Structural maintenance of chromosomes protein 1A	0	0	1	1
Chromodomain-helicase-DNA-binding protein 4	0	0	1	1
Peroxisomal acyl-coenzyme A oxidase 1	0	0	1	1
Delta(24)-sterol reductase	0	0	1	1
Ribosomal protein S6 kinase alpha-1	0	0	1	1
Dual specificity testis-specific protein kinase 1	0	0	1	1
Myosin light chain kinase, smooth muscle	0	0	1	1
Mitogen-activated protein kinase 11	0	0	1	1
Serine/threonine-protein kinase STK11	0	0	1	1
Serine/threonine-protein kinase N2	0	0	1	1
Calcium/calmodulin-dependent protein kinase type IV	0	0	1	1
Mitogen-activated protein kinase kinase kinase 11	0	0	1	1
Discoidin domain-containing receptor 2	0	0	1	1
AP2-associated protein kinase 1	0	0	1	1
Myosin light chain kinase 3	0	0	1	1
Uncharacterized aarF domain-containing protein kinase 5	0	0	1	1
Programmed cell death protein 4	0	0	1	1
Putative heat shock protein HSP 90-beta 2	0	0	1	1
Serine/threonine-protein kinase MRCK alpha	0	0	1	1
Serine/threonine-protein kinase MRCK gamma	0	0	1	1
Acyl-CoA dehydrogenase family member 10	0	0	1	1
Serine/threonine-protein kinase N3	0	0	1	1
Serine/threonine-protein kinase ULK3	0	0	1	1
Uncharacterized protein FLJ45252	0	0	1	1
Acyl-CoA dehydrogenase family member 11	0	0	1	1
Serine/threonine-protein kinase/endoribonuclease IRE2	0	0	1	1
Serine/threonine-protein kinase MARK2	0	0	1	1
ATP-dependent RNA helicase DHX30	0	0	1	1
Serine/threonine-protein kinase TAO1	0	0	1	1
STE20-related kinase adapter protein alpha	0	0	1	1
Myosin-14	0	0	1	1
AarF domain-containing protein kinase 1	0	0	1	1
Mitogen-activated protein kinase kinase kinase kinase 3	0	0	1	1
MAP kinase-activated protein kinase 5	0	0	1	1
Regulatory-associated protein of mTOR	0	1	0	1
Misshapen-like kinase 1	0	0	1	1
Atypical kinase COQ8A, mitochondrial	0	0	1	1
Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma	0	0	1	1
Mitogen-activated protein kinase 15	0	0	1	1
Serine/threonine-protein kinase Nek9	0	0	1	1
ATP-dependent RNA helicase DDX1	0	0	1	1
Mitogen-activated protein kinase kinase kinase kinase 1	0	0	1	1
MAP/microtubule affinity-regulating kinase 4	0	0	1	1
Calcium/calmodulin-dependent protein kinase type 1G	0	0	1	1
Serine/threonine-protein kinase Nek1	0	0	1	1
PAS domain-containing serine/threonine-protein kinase	0	0	1	1
Calcium/calmodulin-dependent protein kinase kinase 2	0	0	1	1
EKC/KEOPS complex subunit TP53RK	0	0	1	1
Dual specificity testis-specific protein kinase 2	0	0	1	1
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase	0	0	1	1
Mitogen-activated protein kinase kinase kinase 5	0	0	1	1
Mitogen-activated protein kinase kinase kinase 3	0	0	1	1
Eukaryotic translation initiation factor 2-alpha kinase 1	0	0	1	1
Target of rapamycin complex subunit LST8	0	1	0	1
Nucleolar GTP-binding protein 1	0	0	1	1
Serine/threonine-protein kinase D2	0	0	1	1
RNA cytidine acetyltransferase	0	0	1	1
Serine/threonine-protein kinase SIK2	0	0	1	1
STE20-like serine/threonine-protein kinase	0	0	1	1
Serine/threonine-protein kinase TAO3	0	0	1	1
dCTP pyrophosphatase 1	0	0	1	1
Dual specificity protein kinase CLK4	0	0	1	1
Casein kinase I isoform gamma-1	0	0	1	1
Serine/threonine-protein kinase mTOR	0	1	0	1
Phenylalanine--tRNA ligase beta subunit	0	0	1	1
Isoleucine--tRNA ligase, mitochondrial	0	0	1	1
BMP-2-inducible protein kinase	0	0	1	1
Obg-like ATPase 1	0	0	1	1
Midasin	0	0	1	1
Interleukin-1 receptor-associated kinase 4	0	0	1	1
Mitogen-activated protein kinase kinase kinase 20	0	0	1	1
Cyclin-dependent kinase 12	0	0	1	1
Serine/threonine-protein kinase 26	0	0	1	1
Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial	0	0	1	1
Serine/threonine-protein kinase NLK	0	0	1	1
5'-AMP-activated protein kinase subunit gamma-2	0	0	1	1
Serine/threonine-protein kinase TBK1	0	0	1	1
Septin-9	0	0	1	1
Ribosomal protein S6 kinase alpha-6	0	0	1	1
TRAF2 and NCK-interacting protein kinase	0	0	1	1
Serine/threonine-protein kinase TAO2	0	0	1	1
Serine/threonine-protein kinase ICK	0	0	1	1
RAC-gamma serine/threonine-protein kinase	0	0	1	1
Serine/threonine-protein kinase SIK3	0	0	1	1
Mitogen-activated protein kinase kinase kinase 2	0	0	1	1
Thyroid hormone receptor-associated protein 3	0	0	1	1
Dual specificity tyrosine-phosphorylation-regulated kinase 1B	0	0	1	1
Mitogen-activated protein kinase kinase kinase kinase 5	0	0	1	1
Receptor-interacting serine/threonine-protein kinase 3	0	0	1	1
Serine/threonine-protein kinase MRCK beta	0	0	1	1
Interleukin-1 receptor-associated kinase 3	0	0	1	1
Serine/threonine-protein kinase 24	0	0	1	1
Casein kinase I isoform gamma-3	0	0	1	1
Mitogen-activated protein kinase kinase kinase 4	0	0	1	1
pregnane X receptor	1	0	0	1
GALC protein	1	0	0	1
Chain X, Thyroid hormone receptor beta-1	0	0	1	1
Chain X, Thyroid hormone receptor beta-1	0	0	1	1
apical membrane antigen 1, AMA1	1	0	0	1
serine/threonine-protein kinase PLK1	1	0	0	1
Thyroid hormone receptor alpha	0	0	1	1
Thyroid hormone receptor beta	0	0	1	1
Proliferating cell nuclear antigen	0	1	0	1
Malate dehydrogenase, mitochondrial	0	1	0	1
Solute carrier organic anion transporter family member 1A2	0	0	0	1
Solute carrier organic anion transporter family member 4C1	0	1	0	1
Monocarboxylate transporter 8	0	0	0	1
Bile acid receptor	0	1	0	1
Solute carrier organic anion transporter family member 1C1	0	0	0	1
Chain A, Trp Rna-binding Attenuation Protein	0	0	1	1
Chain K, Trp Rna-binding Attenuation Protein	0	0	1	1
Chain B, tryptophanyl-tRNA synthetase	0	0	1	1
Chain C, Tryptophanyl-tRNA synthetase II	0	0	1	1
Dihydrofolate reductase	0	2	0	2
Alkaline phosphatase, tissue-nonspecific isozyme	0	1	0	1
Intestinal-type alkaline phosphatase	0	1	0	1
Indoleamine 2,3-dioxygenase 1	0	1	0	2
Tryptophan 2,3-dioxygenase	0	1	0	2
Carbonic anhydrase	0	0	0	1
Large neutral amino acids transporter small subunit 1	0	1	0	1
SLC16A10 protein	0	0	0	1
Uracil nucleotide/cysteinyl leukotriene receptor	0	1	0	1
Carbonic anhydrase	0	0	0	1
Carbonic anhydrase-like protein, putative	0	0	0	1
Tryprostatin B synthase	0	0	0	1
Carbonic anhydrase	0	0	0	1
Carbonic anhydrase	0	0	0	1
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase	0	0	1	1
Carbonic anhydrase	0	0	0	1
Monocarboxylate transporter 10	0	0	0	1
Phospholipase A-2-activating protein	0	1	0	1
Solute carrier family 2, facilitated glucose transporter member 9	0	1	1	2
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Synonyms(2)

Research Excerpts

Overview

Context

Research

Studies (250)

Protein Targets (1,327)

Pre-Hypertension

Synonyms(2)

Research Excerpts

Overview

Context

Research

Studies (250)

Drugs Studied (130)

Protein Targets (1,327)