Page last updated: 2024-09-27

Advanced Sleep Phase Syndrome

Synonyms(16)

Synonym
Delayed Sleep Phase Syndrome
Sleep Disorder, Shift-Work
Delayed Sleep-Phase Syndrome
Non-24 Hour Sleep-Wake Disorder
Sleep-Wake Cycle Disorder
Nonorganic Sleep Wake Cycle Disorders
Sleep-Wake Cycle Disorders
Sleep-Wake Disorder, Non-24 Hour
Sleep-Wake Schedule Disorder
Disturbed Nyctohemeral Rhythm
Nonorganic Sleep Wake Cycle Disorder
Sleep-Wake Schedule Disorders
Circadian Rhythm Sleep Disorders
Circadian Rhythm Sleep Disorder
Advanced Sleep Phase Syndrome
Shift-Work Sleep Disorder

Research Excerpts

Overview

ExcerptReference
"Advanced sleep phase syndrome is characterized by the complaint of persistent early evening sleep onset and early morning awakening."( Chang, AM; Dubocovich, ML; Reid, KJ; Takahashi, JS; Turek, FW; Zee, PC, 2001)
"Circadian rhythm sleep disorders are characterized by complaints of insomnia and excessive sleepiness that are primarily due to alterations in the internal circadian timing system or a misalignment between the timing of sleep and the 24-h social and physical environment."( Barion, A; Zee, PC, 2007)
"Patients with advanced sleep phase syndrome are sleepy in the evening and awaken very early and alert in the morning."( Bramley, TJ; Mitrzyk, BM; Richardson, GS, 2007)
"Circadian rhythm sleep disorders are perhaps the most often overlooked conditions in the differential diagnosis of these symptoms."( Lenz, Mdo C; Martinez, D; Menna-Barreto, L, 2008)
"Circadian rhythm sleep disorders are common in clinical practice."( Bjorvatn, B; Pallesen, S, 2009)
"Circadian rhythm sleep disorders are categorized into six subtypes: Delayed sleep-phase disorder, advanced sleep-phase disorder, irregular sleep-wake rhythm, free-running disorder, jet-lag and shift work disorder."( Bjorvatn, B; Pallesen, S, 2009)
"Circadian rhythm sleep disorders are common conditions manifested as misalignment between the sleep period and the physical/social 24-h environmental cycle."( Lenz, Mdo C; Martinez, D, 2010)
"Circadian rhythm sleep disorders are poorly understood and often misdiagnosed."( Abbas, A; Milles, J; Raju, J; Ramachandran, S, 2010)

Actions

ExcerptReference
"Insomnia and circadian rhythm sleep disorders affect large proportions of the population and have pronounced effects on quality of life and daytime performance."( Nissen, C; Riemann, D; Spiegelhalder, K, 2019)

Treatment

ExcerptReference
"Patients with circadian rhythm sleep disorders, including some blind patients with no light-induced suppression of melatonin, benefit from melatonin treatment."( Brennan, R; Jan, JE; Lyons, CJ, 2007)
"Treatment of circadian rhythm sleep disorders (CRSD) may include light therapy, chronotherapy and melatonin."( Curfs, LM; Duffy, JF; Keijzer, H; Smits, MG, 2014)

Research

Studies (574)

TimeframeStudies, This Condition (%)All Conditions %
pre-19901 (0.17)23.3326
1990's4 (0.70)12.5806
2000's242 (42.16)18.1394
2010's250 (43.55)28.8240
2020's77 (13.41)9.53
DrugIndicatedRelationship StrengthStudiesTrials
gamma-aminobutyric acid0low20
5-hydroxytryptophan0low10
glycine0low10
histamine0low20
melatonin0medium36141
nitrates0low10
nitrites0low10
1-propanol0low10
urea0low10
sk&f-383930low10
hydroxyindoleacetic acid0low20
acebutolol0low10
amantadine0low10
brotizolam0low10
caffeine0medium204
carbamazepine0low10
citalopram0medium11
clonazepam0low10
diazepam0low20
diphenhydramine0low10
gabapentin0low10
haloperidol0low10
indomethacin0low10
lansoprazole0low10
lorazepam0low10
methylphenidate0medium32
metoprolol0low10
mianserin0medium11
midazolam0low10
mirtazapine0medium11
modafinil0medium3616
apnea0low10
nimodipine0low10
oxazepam0medium11
oxidopamine0low10
fenclonine0low10
pentobarbital0low10
prazosin0low10
risperidone0medium64
ritanserin0low10
saccharin0low10
trazodone0medium11
triazolam0medium42
trimeprazine0low10
zaleplon0medium11
zolpidem0medium73
zopiclone0medium32
corticosterone0low40
thyroxine0low10
dextroamphetamine0low10
prednisone0low10
triiodothyronine0low10
alanine0low10
serine0low20
aspartic acid0low20
testosterone propionate0low10
uridine monophosphate0medium11
levodopa0low20
adenosine monophosphate0medium11
threonine0low10
tryptophan0medium43
methylamine0low10
methylprednisolone0low10
thiophenes0low10
pregnenolone0low10
benzoxazoles0low10
methamphetamine0medium21
malondialdehyde0low10
dehydroepiandrosterone sulfate0low10
s,n,n'-tripropylthiocarbamate0low20
gold0low10
uranium0low10
acetylglucosamine0low10
selegiline0low10
cetylpyridinium chloride anhydrous0medium61
pyrrolidine0low10
pregnanolone0low10
glutamic acid0low30
adenosine diphosphate ribose0low10
fomesafen0low10
quinpirole0low10
aripiprazole0low20
adenosine0low10
n-acetylaspartic acid0low20
6-sulfatoxymelatonin0medium214
triazoles0medium41
fluorodeoxyglucose f180low10
s200980medium101
nicotine0low10
homocysteine0low20
phenoxy radical0low10
ramelteon0medium91
beta-methyl-6-chloromelatonin0low10
benzofurans0medium162
prostaglandin d20low10
lithium0low10
thioperamide0low10
linoleic acid0low10
eprosartan0low10
entacapone0low20
morphine0low10
mdl 1009070low10
fluvoxamine0low10
ciproxifan0low10
sb 334867-a0low10
dibutyl phthalate0low10
benzonitrile, 4-(2-(2-((2r)-2-methyl-1-pyrrolidinyl)ethyl)-5-benzofuranyl)-0low10
tasimelteon0medium152
alpha-synuclein0low10
losartan potassium0low10
pituitrin0low10
nad0low10
xenin 250low10
astressin0low10
glucagon-like peptide 10low10
sodium oxybate0medium31
suvorexant0medium41
neurotensin0low10
piperidines0medium11
heme0low10
peptide yy0low10
vitamin b 120low80
oxyntomodulin0low10
clozapine0low10
leptin0low40

Protein Targets (1,154)

ProteinPotency MeasurementsInhibition MeasurementsActivation MeasurementsDrugs
Solute carrier family 22 member 1 011015
Beta-2 adrenergic receptor0325
Beta-1 adrenergic receptor0426
Beta-3 adrenergic receptor0022
5-hydroxytryptamine receptor 1A025328
Putative glycosyltransferase WbgO0001
Cytochrome P450 3A4010113
Cannabinoid receptor 10101
Killer cell lectin-like receptor subfamily B member 1A0101
Early activation antigen CD690101
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE160016
Chain A, Membrane lipoprotein tmpC0011
Chain A, Membrane lipoprotein tmpC0011
Chain A, Membrane lipoprotein tmpC0011
Chain A, Structure of PAE2307 in complex with adenosine0011
Chain B, Structure of PAE2307 in complex with adenosine0011
Chain A, ADENOSINE RECEPTOR A2A0101
Chain A, ADENOSINE RECEPTOR A2A0101
Chain A, tRNA (guanine-N(1)-)-methyltransferase0011
Chain A, Uncharacterized protein MJ08830011
AR protein450045
signal transducer and activator of transcription 6, interleukin-4 induced2002
regulator of G-protein signaling 4180018
glucocorticoid receptor [Homo sapiens]360036
retinoid X nuclear receptor alpha180018
estrogen nuclear receptor alpha470047
NPYLR7B0011
arylsulfatase A160016
IDH18008
Histone H2A.x9009
glycogen synthase kinase-3 beta isoform 10011
mitogen-activated protein kinase 1120012
flap endonuclease 16006
nuclear receptor ROR-gamma isoform 1140014
peripheral myelin protein 22160016
survival motor neuron protein isoform d9009
high affinity choline transporter 1 isoform a0101
Sodium/nucleoside cotransporter 10202
Calcium dependent protein kinase0101
Mitogen-activated protein kinase kinase kinase 70022
Sodium/nucleoside cotransporter 20202
Voltage-dependent calcium channel gamma-2 subunit130013
Rap guanine nucleotide exchange factor 34004
Purine nucleoside phosphorylase0101
Epidermal growth factor receptor0303
Phosphoglycerate kinase 1 0101
Adenosine deaminase0001
Avidin0011
Adenosine deaminase0001
Glyceraldehyde-3-phosphate dehydrogenase0303
Receptor tyrosine-protein kinase erbB-20101
Insulin receptor0001
Phosphoglycerate kinase 20101
Heat shock protein HSP 90-alpha0112
Platelet-derived growth factor receptor beta0001
Adenosine receptor A307210
Heat shock 70 kDa protein 1A 0101
Heat shock cognate 71 kDa protein0011
Fibroblast growth factor receptor 10001
Inosine-5'-monophosphate dehydrogenase 20101
Endoplasmin0112
Glutamate receptor 2142117
Inosine-5'-monophosphate dehydrogenase 1 0101
Fibroblast growth factor receptor 20001
Fibroblast growth factor receptor 40001
Fibroblast growth factor receptor 30001
Streptavidin0011
Adenosylhomocysteinase0001
Adenosine receptor A108112
Adenosine receptor A30202
Adenosine receptor A2a06412
Adenosine receptor A2b0215
Adenosine receptor A2b0315
Adenylate kinase 2, mitochondrial0203
Adenosine receptor A106413
Adenosine receptor A2a06111
Adenylate kinase isoenzyme 1 0203
Phosphatidylinositol 4-kinase alpha0203
Adenosine receptor A10112
Adenosine kinase0001
Adenosine deaminase 0001
Equilibrative nucleoside transporter 20202
Phosphatidylinositol 4-kinase type 2-beta0203
Histone-lysine N-methyltransferase, H3 lysine-79 specific0101
Equilibrative nucleoside transporter 10202
Phosphatidylinositol 4-kinase type 2-alpha0203
Solute carrier family 28 member 30202
Adenosine kinase0102
Phosphatidylinositol 4-kinase beta0203
5-methylthioadenosine/S-adenosylhomocysteine deaminase0001
Adenosine transporter 10001
TDP1 protein360036
Transient receptor potential cation channel subfamily M member 20112
Chain A, Glycogen Phosphorylase B0011
Chain B, Glycogen Phosphorylase B0011
Chain A, ADP-dependent glucokinase0101
Chain A, Ribonuclease pancreatic0101
Chain A, Ribonuclease pancreatic0101
Chain A, phosphodiesterase-nucleotide pyrophosphatase0101
Chain A, GLYCOGEN PHOSPHORYLASE B0011
Chain B, GLYCOGEN PHOSPHORYLASE B0011
Chain A, GLYCOGEN PHOSPHORYLASE B0011
RAR-related orphan receptor gamma250025
estrogen-related nuclear receptor alpha390039
euchromatic histone-lysine N-methyltransferase 2460046
v-jun sarcoma virus 17 oncogene homolog (avian)160016
2'-deoxynucleoside 5'-phosphate N-hydrolase 10101
2'-deoxynucleoside 5'-phosphate N-hydrolase 10101
5'-AMP-activated protein kinase subunit beta-20011
Alcohol dehydrogenase E chain0101
Alcohol dehydrogenase S chain0101
L-lactate dehydrogenase A chain0112
Adenylate kinase isoenzyme 10001
Fructose-1,6-bisphosphatase 10101
Alkaline phosphatase, tissue-nonspecific isozyme0102
Fructose-1,6-bisphosphatase 10101
2-dehydropantoate 2-reductase0112
Inosine-5'-monophosphate dehydrogenase0101
Cytochrome P450 2C9 011012
Proto-oncogene tyrosine-protein kinase Src0101
Amine oxidase [flavin-containing] B0506
5'-nucleotidase0001
Choline O-acetyltransferase0101
GTP:AMP phosphotransferase AK3, mitochondrial0001
P2Y purinoceptor 20011
P2Y purinoceptor 10011
P2Y purinoceptor 10011
5'-AMP-activated protein kinase subunit gamma-10022
5'-AMP-activated protein kinase catalytic subunit alpha-20011
Adenylate kinase 2, mitochondrial0001
Glycine--tRNA ligase0101
5'-AMP-activated protein kinase catalytic subunit alpha-10022
Adenosine deaminase-like protein0001
Protease 0314
P2Y purinoceptor 110011
Histamine H3 receptor0516
5'-AMP-activated protein kinase subunit gamma-30011
5'-AMP-activated protein kinase subunit gamma-20011
5'-AMP-activated protein kinase subunit beta-10022
ATP-dependent phosphofructokinase210021
Chain A, TYROSYL-DNA PHOSPHODIESTERASE130013
Carbonic anhydrase 106012
Carbonic anhydrase 206013
Alanine racemase, biosynthetic0001
5-hydroxytryptamine receptor 1D0205
Glutamate receptor ionotropic, NMDA 1 010215
Proton-coupled amino acid transporter 10505
Adenosine deaminase0001
Carbonic anhydrase 40003
acetylcholinesterase120012
thioredoxin reductase260026
NFKB1 protein, partial7007
GLI family zinc finger 3280028
thyroid stimulating hormone receptor190019
EWS/FLI fusion protein190019
putative alpha-glucosidase1001
thyroid hormone receptor beta isoform 2340034
heat shock protein beta-1120012
histone acetyltransferase KAT2A isoform 18008
lamin isoform A-delta10370037
Solute carrier family 22 member 20507
Glutamate receptor ionotropic, NMDA 2D0303
Glutamate receptor ionotropic, NMDA 3B0303
Matrix protein 20112
Matrix protein 20123
Spike glycoprotein160016
Glutamate receptor ionotropic, NMDA 2A 09214
Glutamate receptor ionotropic, NMDA 2B09214
Glutamate receptor ionotropic, NMDA 2C09214
Glutamate receptor ionotropic, NMDA 10404
Glutamate receptor ionotropic, NMDA 2A0404
Glutamate receptor ionotropic, NMDA 2B0404
Glutamate receptor ionotropic, NMDA 2C0303
Glutamate receptor ionotropic, NMDA 2D09214
Solute carrier family 22 member 10607
Glutamate receptor ionotropic, NMDA 3A0303
Glutamate receptor ionotropic, NMDA 3B09214
Multidrug and toxin extrusion protein 10505
Solute carrier family 22 member 20607
Glutamate receptor ionotropic, NMDA 3A09214
ATAD5 protein, partial120012
Microtubule-associated protein tau140014
Bloom syndrome protein isoform 1130013
D(1A) dopamine receptor160016
neuropeptide S receptor isoform A9009
Chain A, JmjC domain-containing histone demethylation protein 3A7007
5-hydroxytryptamine receptor 3E0404
hypoxia-inducible factor 1 alpha subunit130013
SMAD family member 27007
Fumarate hydratase7007
USP1 protein, partial200020
PPM1D protein2002
SMAD family member 37007
estrogen receptor 2 (ER beta)180018
nuclear receptor subfamily 1, group I, member 3230023
progesterone receptor220022
retinoic acid nuclear receptor alpha variant 1260026
farnesoid X nuclear receptor170017
pregnane X nuclear receptor280028
G180018
cytochrome P450 2D6170017
polyprotein7007
67.9K protein6006
peroxisome proliferator-activated receptor delta140014
peroxisome proliferator activated receptor gamma170017
vitamin D (1,25- dihydroxyvitamin D3) receptor220022
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)4004
thyroid stimulating hormone receptor100010
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a110011
lysosomal alpha-glucosidase preproprotein4004
mu-type opioid receptor isoform MOR-10011
nuclear factor erythroid 2-related factor 2 isoform 26006
potassium voltage-gated channel subfamily H member 2 isoform d170017
transcriptional regulator ERG isoform 34004
nuclear factor erythroid 2-related factor 2 isoform 1270027
geminin290029
5-hydroxytryptamine receptor 2A0011
ATP-binding cassette sub-family C member 3030030
Multidrug resistance-associated protein 4031032
5-hydroxytryptamine receptor 3A0202
5-hydroxytryptamine receptor 3B0404
Bile salt export pump040040
Interferon beta190019
HLA class I histocompatibility antigen, B alpha chain 180018
Cellular tumor antigen p53240024
ATP-dependent translocase ABCB109016
5-hydroxytryptamine receptor 1A012820
5-hydroxytryptamine receptor 2C015217
Neuronal acetylcholine receptor subunit alpha-435211
Neuronal acetylcholine receptor subunit beta-235211
D(2) dopamine receptor020328
5-hydroxytryptamine receptor 2A016218
Alpha-1B adrenergic receptor020424
Alpha-2C adrenergic receptor025228
D013014
Muscarinic acetylcholine receptor M3014115
D(1A) dopamine receptor013116
D(4) dopamine receptor011218
D(1B) dopamine receptor0507
Alpha-1D adrenergic receptor018422
Alpha-1D adrenergic receptor020123
5-hydroxytryptamine receptor 2A026129
5-hydroxytryptamine receptor 2C028129
D(4) dopamine receptor0606
Histamine H1 receptor0629
Sodium-dependent serotonin transporter023326
5-hydroxytryptamine receptor 7 0819
5-hydroxytryptamine receptor 70808
Alpha-1A adrenergic receptor010115
Histamine H1 receptor029435
Alpha-1B adrenergic receptor0619
D(3) dopamine receptor019326
5-hydroxytryptamine receptor 2B028129
Alpha-1A adrenergic receptor021425
5-hydroxytryptamine receptor 3A0505
5-hydroxytryptamine receptor 60709
3-hydroxy-3-methylglutaryl-coenzyme A reductase 0303
D(2) dopamine receptor020426
Inositol monophosphatase 18008
Potassium voltage-gated channel subfamily H member 2026026
5-hydroxytryptamine receptor 3D0404
Multidrug and toxin extrusion protein 20303
5-hydroxytryptamine receptor 3C0404
Inositol hexakisphosphate kinase 1180018
Canalicular multispecific organic anion transporter 1026026
Histamine H3 receptor012621
cytochrome P450 2C9, partial180018
Chain A, Ferritin light chain8008
phosphopantetheinyl transferase170017
aldehyde dehydrogenase 1 family, member A1210021
cytochrome P450 2C19 precursor120012
lethal factor (plasmid)9009
Metabotropic glutamate receptor 60124
Excitatory amino acid transporter 40202
Glutamate transporter homolog0011
N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase0101
Excitatory amino acid transporter 10304
Excitatory amino acid transporter 20304
Excitatory amino acid transporter 30304
Metabotropic glutamate receptor 10124
Metabotropic glutamate receptor 20124
Carbonic anhydrase-like protein, putative0005
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a210021
Platelet-activating factor receptor0101
ATPase family AAA domain-containing protein 5120012
Ataxin-2200020
Chain A, Glycogen Phosphorylase0101
Chain A, Glycogen phosphorylase, liver form0011
Chain A, glycogen phosphorylase, liver form0011
Chain A, Glycogen phosphorylase, liver form0011
Chain A, Glycogen phosphorylase, liver form0011
Chain A, Chitinase0101
GLS protein190019
atrial natriuretic peptide receptor 1 precursor3003
chromobox protein homolog 1240024
thyroid hormone receptor beta isoform a110011
DNA polymerase beta2002
DNA polymerase kappa isoform 1100010
muscarinic acetylcholine receptor M1170017
Potassium channel subfamily K member 20123
Glycogen phosphorylase, muscle form0101
Renin0101
Cholinesterase0505
Glycogen phosphorylase, liver form0101
Glycogen phosphorylase, muscle form0101
Replicase polyprotein 1ab0101
Replicase polyprotein 1ab0303
Amine oxidase [flavin-containing] A0505
Acetylcholinesterase0505
Amine oxidase [flavin-containing] B0617
cAMP-specific 3',5'-cyclic phosphodiesterase 4A0101
Vasopressin V2 receptor0001
Serine/threonine-protein kinase mTOR0101
Adenosine receptor A2a0101
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform 0101
DNA-dependent protein kinase catalytic subunit0101
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B0101
Adenylate cyclase type 10001
Chitotriosidase-10101
Serine-protein kinase ATM0101
Serine/threonine-protein kinase ATR0101
Adenosine receptor A2b0102
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C0101
Palmitoleoyl-protein carboxylesterase NOTUM0224
Endochitinase B10101
Muscarinic acetylcholine receptor0001
Phosphodiesterase 0101
Broad substrate specificity ATP-binding cassette transporter ABCG20304
Guanine deaminase0101
Chain A, Beta-lactamase7007
Vpr1001
Bile salt export pump0303
Albumin0066
Major prion protein0022
Sodium channel protein type 1 subunit alpha0202
Sodium channel protein type 2 subunit alpha0303
Sodium channel protein type 3 subunit alpha0202
UDP-glucuronosyltransferase 2B70407
Cytochrome P450 2B60011
Sodium channel protein type 4 subunit alpha0304
Cytochrome P450 2J209010
Sodium channel protein type 9 subunit alpha0303
Frizzled-80011
P2X purinoceptor 40101
Chain A, Putative fructose-1,6-bisphosphate aldolase5005
Chain A, serum paraoxonase0101
Carbonic anhydrase 120205
Carbonic anhydrase 30205
Neutrophil cytosol factor 10101
Carbonic anhydrase 40407
Carbonic anhydrase 60205
Carbonic anhydrase 5A, mitochondrial0205
Carbonic anhydrase 70205
Carbonic anhydrase 90205
Carbonic anhydrase 130102
Poly [ADP-ribose] polymerase tankyrase-20101
Carbonic anhydrase 140205
Carbonic anhydrase 5B, mitochondrial0205
caspase 7, apoptosis-related cysteine protease8008
caspase-38008
activating transcription factor 68008
thyrotropin-releasing hormone receptor1001
vitamin D3 receptor isoform VDRA120012
Caspase-20011
glp-1 receptor, partial8008
Gamma-aminobutyric acid receptor subunit pi1715436
Gamma-aminobutyric acid receptor subunit alpha-10406
Gamma-aminobutyric acid receptor subunit beta-10406
Gamma-aminobutyric acid receptor subunit alpha-20406
Gamma-aminobutyric acid receptor subunit alpha-30406
Gamma-aminobutyric acid receptor subunit alpha-1011718
Gamma-aminobutyric acid receptor subunit beta-11715436
Translocator protein0528
Gamma-aminobutyric acid receptor subunit delta1715436
Gamma-aminobutyric acid receptor subunit gamma-2010616
Gamma-aminobutyric acid receptor subunit gamma-21715537
Gamma-aminobutyric acid receptor subunit alpha-51715436
Gamma-aminobutyric acid receptor subunit alpha-31715436
Gamma-aminobutyric acid receptor subunit alpha-40406
Gamma-aminobutyric acid receptor subunit gamma-20406
Gamma-aminobutyric acid receptor subunit gamma-11715436
Gamma-aminobutyric acid receptor subunit alpha-21715436
Gamma-aminobutyric acid receptor subunit alpha-41715436
Gamma-aminobutyric acid receptor subunit beta-3011415
Gamma-aminobutyric acid receptor subunit gamma-31715436
Gamma-aminobutyric acid receptor subunit alpha-61715436
Cholecystokinin receptor type A0404
Gastrin/cholecystokinin type B receptor0303
Gamma-aminobutyric acid receptor subunit alpha-509716
Gamma-aminobutyric acid receptor subunit alpha-309514
Gamma-aminobutyric acid receptor subunit alpha-209615
Gamma-aminobutyric acid receptor subunit alpha-11715537
Gamma-aminobutyric acid receptor subunit beta-31715436
Gamma-aminobutyric acid receptor subunit beta-21715537
GABA theta subunit1715436
Gamma-aminobutyric acid receptor subunit epsilon1715436
Chain A, 2-oxoglutarate Oxygenase140014
cytochrome P450 2D6 isoform 1150015
cytochrome P450 2C9 precursor130013
UDP-glucuronosyltransferase 1-60203
UDP-glucuronosyltransferase 1A1 0303
UDP-glucuronosyltransferase 1A40204
UDP-glucuronosyltransferase 2B10 0202
Histamine H2 receptor131119
Chain A, Cruzipain3003
endonuclease IV4004
chaperonin-containing TCP-1 beta subunit homolog1001
Estrogen receptor 10101
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)130013
PINK11001
cytochrome P450 family 3 subfamily A polypeptide 4230023
Parkin5005
bromodomain adjacent to zinc finger domain 2B100010
estrogen receptor beta isoform 10101
importin subunit beta-1 isoform 12002
snurportin-12002
GTP-binding nuclear protein Ran isoform 11001
cytochrome P450 3A4 isoform 1170017
M-phase phosphoprotein 8100010
Aldo-keto reductase family 1 member B1017017
Muscarinic acetylcholine receptor M4012113
Muscarinic acetylcholine receptor M5013013
Alpha-2A adrenergic receptor025228
Muscarinic acetylcholine receptor M1013114
Alpha-2B adrenergic receptor021022
Sodium-dependent noradrenaline transporter 021223
Cruzipain0101
5-hydroxytryptamine receptor 1B015116
Mu-type opioid receptor010415
Sodium-dependent dopamine transporter 013114
Sigma non-opioid intracellular receptor 1016016
NPC intracellular cholesterol transporter 1 precursor5005
ras-related protein Rab-9A7007
Histamine H2 receptor012214
Histamine H4 receptor07413
Sodium-dependent noradrenaline transporter0101
5-hydroxytryptamine receptor 4020020
Tryptophan 5-hydroxylase 10202
Angiotensin-converting enzyme013013
Aldo-keto reductase family 1 member B10202
Aromatase0101
Sodium-dependent dopamine transporter012315
Sodium-dependent serotonin transporter09110
5-hydroxytryptamine receptor 70505
Sigma intracellular receptor 20505
Sodium-dependent serotonin transporter0101
Sodium-dependent dopamine transporter0101
Nuclear receptor subfamily 3 group C member 3 012012
Sigma non-opioid intracellular receptor 10617
Transporter013115
Gamma-aminobutyric acid receptor subunit pi0606
Gamma-aminobutyric acid receptor subunit delta0606
Gamma-aminobutyric acid receptor subunit beta-10729
Translocator protein0202
Translocator protein0404
Gamma-aminobutyric acid receptor subunit beta-207613
Gamma-aminobutyric acid receptor subunit alpha-40729
Gamma-aminobutyric acid receptor subunit epsilon0606
Gamma-aminobutyric acid receptor subunit alpha-608210
Gamma-aminobutyric acid receptor subunit gamma-10606
Gamma-aminobutyric acid receptor subunit gamma-30617
Gamma-aminobutyric acid receptor subunit theta0606
Chain A, HADH2 protein120012
Chain B, HADH2 protein120012
Luciferase9009
Beta-1 adrenergic receptor 0112
glucocerebrosidase6006
Adenylate cyclase type 1 0202
peripheral myelin protein 22 isoform 1110011
atrial natriuretic peptide receptor 2 precursor3003
DNA polymerase iota isoform a (long)9009
short transient receptor potential channel 6 isoform 10011
transient receptor potential cation channel subfamily V member 12002
Polyunsaturated fatty acid lipoxygenase ALOX15B6006
Voltage-dependent L-type calcium channel subunit alpha-1F0606
Muscarinic acetylcholine receptor M20819
Muscarinic acetylcholine receptor M10606
Muscarinic acetylcholine receptor M30606
Muscarinic acetylcholine receptor M40707
Muscarinic acetylcholine receptor M50707
Calmodulin-10101
Beta-2 adrenergic receptor0404
Cytochrome P450 2D60506
Muscarinic acetylcholine receptor M20606
Beta-1 adrenergic receptor0415
D(3) dopamine receptor09112
Alpha-2B adrenergic receptor08311
D(2) dopamine receptor0505
Endothelin receptor type B0303
Adenylate cyclase type 30202
Alpha-2C adrenergic receptor08311
Alpha-2A adrenergic receptor08311
5-hydroxytryptamine receptor 3A0404
Endothelin receptor type B0303
D(1B) dopamine receptor0505
Beta-3 adrenergic receptor0202
Adenylate cyclase type 20202
Adenylate cyclase type 40202
5-hydroxytryptamine receptor 1D0718
5-hydroxytryptamine receptor 1F0718
5-hydroxytryptamine receptor 2B012315
Histamine H1 receptor0718
Cytochrome P450 2C190304
5-hydroxytryptamine receptor 2C 0404
5-hydroxytryptamine receptor 2A0404
5-hydroxytryptamine receptor 3A0516
Adenylate cyclase type 80202
5-hydroxytryptamine receptor 5A0101
D(2) dopamine receptor0202
D(3) dopamine receptor0202
Gastrin/cholecystokinin type B receptor0202
D(2) dopamine receptor0202
Calmodulin 0011
Voltage-dependent L-type calcium channel subunit alpha-1D 0606
5-hydroxytryptamine receptor 2B0404
Adenylate cyclase type 60202
Adenylate cyclase type 50202
5-hydroxytryptamine receptor 40202
Voltage-dependent L-type calcium channel subunit alpha-1S0606
Voltage-dependent L-type calcium channel subunit alpha-1C0606
Transporter0404
Cholecystokinin receptor type A0303
5-hydroxytryptamine receptor 1A0303
Adenylyl cyclase 7 0202
D0404
5-hydroxytryptamine receptor 3B0516
pregnane X receptor4004
GALC protein3003
Thrombopoietin4004
nonstructural protein 15005
serine/threonine-protein kinase mTOR isoform 15005
Solute carrier family 22 member 30305
Solute carrier family 22 member 30202
Sex hormone-binding globulin0022
Corticosteroid-binding globulin0202
Mineralocorticoid receptor 0011
Androgen receptor0404
C-8 sterol isomerase0202
Solute carrier organic anion transporter family member 1A10102
Nuclear receptor ROR-gamma6006
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase0202
Solute carrier organic anion transporter family member 1A40104
Solute carrier organic anion transporter family member 1A50003
Steryl-sulfatase0001
Multidrug resistance-associated protein 1 0102
Solute carrier organic anion transporter family member 1A20003
Solute carrier organic anion transporter family member 1A30104
G-protein coupled bile acid receptor 10011
ATP-binding cassette sub-family C member 110001
Solute carrier organic anion transporter family member 1B30204
Solute carrier family 22 member 110001
Solute carrier organic anion transporter family member 1A10001
Solute carrier organic anion transporter family member 1B20001
Solute carrier organic anion transporter family member 1B10205
Alpha-1B adrenergic receptor 0011
cellular tumor antigen p53 isoform a4004
Alpha-1A adrenergic receptor0112
Phenylethanolamine N-methyltransferase0101
5-hydroxytryptamine receptor 60213
5-hydroxytryptamine receptor 5A0213
5-hydroxytryptamine receptor 5B0213
Amine oxidase [flavin-containing] B0404
5-hydroxytryptamine receptor 4 0213
Trace amine-associated receptor 10022
Trace amine-associated receptor 10022
Trace amine-associated receptor 10022
Trace amine-associated receptor 10022
Gamma-aminobutyric acid 0123
Fatty acid-binding protein, liver0202
Alpha-1-acid glycoprotein 10001
Albumin0146
Gamma-aminobutyric acid receptor subunit alpha-60123
Gamma-aminobutyric acid receptor subunit gamma-20123
Gamma-aminobutyric acid receptor subunit delta0123
Gamma-aminobutyric acid receptor subunit alpha-20123
Gamma-aminobutyric acid receptor subunit alpha-30123
Gamma-aminobutyric acid receptor subunit gamma-30123
Gamma-aminobutyric acid receptor subunit beta-10123
Gamma-aminobutyric acid receptor subunit alpha-10224
Gamma-aminobutyric acid receptor subunit beta-30123
Neuronal acetylcholine receptor subunit alpha-70427
Gamma-aminobutyric acid receptor subunit alpha-50123
Gamma-aminobutyric acid receptor subunit pi0123
Sphingosine-1-phosphate lyase 10202
Gamma-aminobutyric acid receptor subunit alpha-40123
Gamma-aminobutyric acid receptor subunit theta0123
Gamma-aminobutyric acid receptor subunit gamma-10123
huntingtin isoform 22002
Histamine N-methyltransferase0001
Sodium channel protein type 5 subunit alpha0404
Calcium release-activated calcium channel protein 10101
Protein orai-20101
Protein orai-30101
Histamine H3 receptor0203
histone deacetylase 9 isoform 32002
histone-lysine N-methyltransferase 2A isoform 2 precursor4004
UDP-glucuronosyltransferase 1A90105
Catechol O-methyltransferase0101
Catechol O-methyltransferase0101
UDP-glucuronosyltransferase 2B150001
Alpha-ketoglutarate-dependent dioxygenase FTO0202
Type-1A angiotensin II receptor 0202
Type-1B angiotensin II receptor0303
Type-1 angiotensin II receptor0001
Type-2 angiotensin II receptor0505
Voltage-dependent T-type calcium channel subunit alpha-1G0112
Voltage-dependent T-type calcium channel subunit alpha-1H0112
Cannabinoid receptor 10404
Delta-type opioid receptor0405
Voltage-dependent L-type calcium channel subunit beta-10101
Voltage-dependent calcium channel subunit alpha-2/delta-10101
Voltage-dependent N-type calcium channel subunit alpha-1B0303
Voltage-dependent N-type calcium channel subunit alpha-1B0101
Potassium channel subfamily K member 2 0101
Voltage-dependent T-type calcium channel subunit alpha-1I0112
Prostaglandin D2 receptor 20213
Cytochrome P450 1A2 0202
thioredoxin glutathione reductase4004
ubiquitin carboxyl-terminal hydrolase 2 isoform a3003
Voltage-dependent calcium channel subunit alpha-2/delta-10101
Gamma-aminobutyric acid receptor subunit rho-30011
Hsf1 protein0011
Histone deacetylase 30303
Gamma-aminobutyric acid type B receptor subunit 20011
Gamma-aminobutyric acid type B receptor subunit 20101
Sodium- and chloride-dependent GABA transporter 10404
Gamma-aminobutyric acid receptor subunit rho-10022
Gamma-aminobutyric acid receptor subunit rho-20011
Sodium- and chloride-dependent GABA transporter 10101
Sodium- and chloride-dependent taurine transporter0101
Sodium- and chloride-dependent GABA transporter 20404
Sodium- and chloride-dependent GABA transporter 30404
Sodium- and chloride-dependent GABA transporter 10101
Sodium- and chloride-dependent GABA transporter 20202
Sodium- and chloride-dependent GABA transporter 30202
Sodium- and chloride-dependent betaine transporter0404
Sodium- and chloride-dependent betaine transporter0101
Sodium- and chloride-dependent GABA transporter 30101
Histone deacetylase 40303
4-aminobutyrate aminotransferase, mitochondrial0001
4-aminobutyrate aminotransferase, mitochondrial0001
TAR DNA-binding protein 436006
Histone deacetylase 10303
Sterol O-acyltransferase 10011
Histone deacetylase 70303
Histone deacetylase 20303
Polyamine deacetylase HDAC100303
Histone deacetylase 11 0303
Histone deacetylase 80303
Platelet glycoprotein VI0011
Sodium- and chloride-dependent GABA transporter 20101
Histone deacetylase 60303
Gamma-aminobutyric acid type B receptor subunit 10011
Histone deacetylase 90303
Histone deacetylase 50303
Gamma-aminobutyric acid type B receptor subunit 10101
Glucagon-like peptide 1 receptor0011
Glucagon-like peptide 1 receptor0112
Glucagon receptor0011
Glucagon receptor0011
Chain A, GLUTAMATE RECEPTOR SUBUNIT 20101
Chain A, Glutamate Receptor Subunit 20101
Chain B, Glutamate Receptor Subunit 20101
Chain A, Slr1257 protein0011
Chain A, Glucosamine--fructose-6-phosphate aminotransferase [isomerizing]0101
beta-2 adrenergic receptor1001
peptidyl-prolyl cis-trans isomerase NIMA-interacting 14004
Metabotropic glutamate receptor 80202
Glutathione reductase, mitochondrial0202
Bifunctional aspartokinase/homoserine dehydrogenase 10101
Prothrombin0022
Integrin beta-33014
Integrin alpha-IIb3014
ATP-citrate synthase 0101
Glutamate receptor 11214
Glutamate receptor 31214
Glutamate receptor 41214
Glutamate receptor ionotropic, kainate 10213
Metabotropic glutamate receptor 10213
Metabotropic glutamate receptor 20011
Metabotropic glutamate receptor 30011
Metabotropic glutamate receptor 40112
Metabotropic glutamate receptor 50123
Metabotropic glutamate receptor 60011
Metabotropic glutamate receptor 70011
Glutamate receptor ionotropic, kainate 10112
Metabotropic glutamate receptor 50124
Glutamate receptor ionotropic, kainate 20213
Glutamate receptor 10213
Glutamate receptor 20213
Glutamate receptor 30112
Glutamate receptor ionotropic, kainate 30202
Metabotropic glutamate receptor 80011
Glutamate receptor 40213
Excitatory amino acid transporter 3 0001
Glutamate racemase0001
Metabotropic glutamate receptor 80112
Fatty-acid amide hydrolase 10202
Glutamate receptor ionotropic, kainate 40202
Glutamate carboxypeptidase 20101
Glutamate receptor ionotropic, kainate 20112
Glutamate receptor ionotropic, kainate 30101
Metabotropic glutamate receptor 70113
Metabotropic glutamate receptor 30113
Metabotropic glutamate receptor 40113
Glutamate receptor ionotropic, kainate 50101
Glutamate receptor ionotropic, kainate 50202
Glutamate racemase0001
Prolyl 4-hydroxylase0101
Glycine receptor subunit alpha-10022
Sodium- and chloride-dependent glycine transporter 10101
Large neutral amino acids transporter small subunit 10303
Serine racemase0101
Olfactory receptor 51E20022
Sodium- and chloride-dependent glycine transporter 20101
POU domain, class 2, transcription factor 10001
Nischarin0101
15-lipoxygenase, partial6006
Cocaine esterase0202
Transient receptor potential cation channel subfamily V member 10101
Voltage-dependent L-type calcium channel subunit alpha-1C0202
Vitamin D-binding protein0101
HLA class I histocompatibility antigen, A alpha chain 0011
Integrin beta-10101
Integrin alpha-40101
Carbonyl reductase [NADPH] 10001
Delta-type opioid receptor0719
Mu-type opioid receptor07111
Kappa-type opioid receptor0416
Sodium channel protein type 1 subunit alpha0101
Kappa-type opioid receptor0404
5-hydroxytryptamine receptor 2A0213
D(1A) dopamine receptor3205
AP-2 complex subunit sigma0101
N-acetyltransferase Eis0202
Sodium channel protein type 7 subunit alpha0101
Calcitonin gene-related peptide type 1 receptor0101
Genome polyprotein 0202
Sigma intracellular receptor 20101
Sigma non-opioid intracellular receptor 10314
Zinc finger protein 6640101
Vesicular acetylcholine transporter0101
Sodium channel protein type 2 subunit alpha0101
Transient receptor potential cation channel subfamily V member 40101
Sodium channel protein type 3 subunit alpha0101
Sodium channel protein type 11 subunit alpha0101
Sodium channel protein type 8 subunit alpha0101
Transient receptor potential cation channel subfamily V member 20101
Sodium channel protein type 10 subunit alpha0101
Chain A, CARBONIC ANHYDRASE II0011
Chain A, Protein (female-specific Histamine Binding Protein 2)0011
aryl hydrocarbon receptor nuclear translocator0001
apical membrane antigen 1, AMA15005
transforming acidic coiled-coil-containing protein 30001
Plasma kallikrein0003
Macrophage migration inhibitory factor0202
Carbonic anhydrase0205
Carbonic anhydrase0105
Histamine H3 receptor0213
Histamine N-methyltransferase 0101
Glutaminyl-peptide cyclotransferase0101
Carbonic anhydrase 0004
Carbonic anhydrase0004
Carbonic anhydrase0105
Carbonic anhydrase 0004
Equilibrative nucleoside transporter 40001
Histamine H4 receptor0224
Histamine H4 receptor0235
Histamine H4 receptor 0101
Carbonic anhydrase 150205
Carbonic anhydrase 130003
Carboxylic ester hydrolase 0001
N(G),N(G)-dimethylarginine dimethylaminohydrolase 10202
Delta-type opioid receptor0326
Kappa-type opioid receptor0337
Smad35005
hypothetical protein, conserved2002
alpha-galactosidase4004
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 18008
urokinase-type plasminogen activator precursor1001
plasminogen precursor1001
urokinase plasminogen activator surface receptor precursor1001
Uracil nucleotide/cysteinyl leukotriene receptor0303
Chain A, membrane-associated prostaglandin E synthase-20101
interleukin 83003
aryl hydrocarbon receptor130013
Prostaglandin-H2 D-isomerase0101
Prostaglandin E synthase0101
Solute carrier family 22 member 60101
Prostaglandin G/H synthase 1 0203
Prostaglandin G/H synthase 2 0102
3',5'-cyclic-AMP phosphodiesterase 0101
Solute carrier organic anion transporter family member 2B1 0202
Cytochrome c oxidase subunit 20101
Phospholipase A2, major isoenzyme0101
Prostaglandin G/H synthase 10203
Procathepsin L0101
Interleukin-80101
Androgen receptor0214
Polyunsaturated fatty acid 5-lipoxygenase0102
Aldo-keto reductase family 1 member B10101
Aldo-keto reductase family 1 member C40101
Prostaglandin G/H synthase 10101
Prostaglandin G/H synthase 10303
Thromboxane-A synthase 0101
Serum paraoxonase/arylesterase 10101
Indoleamine 2,3-dioxygenase 10202
Caspase-10001
Nitric oxide synthase, inducible0101
Substance-P receptor0202
Prostaglandin E2 receptor EP3 subtype0101
Prostaglandin E2 receptor EP4 subtype0101
Bifunctional epoxide hydrolase 20101
Prostaglandin G/H synthase 20215
Prostaglandin G/H synthase 2 0101
Prostaglandin E2 receptor EP1 subtype0101
Peroxisome proliferator-activated receptor gamma0055
Aldo-keto reductase family 1 member C30303
C-X-C chemokine receptor type 30202
Aldo-keto reductase family 1 member C2 0101
Guanine nucleotide-binding protein G3003
Prostaglandin D2 receptor 0202
Prostaglandin G/H synthase 20303
Lactoylglutathione lyase0101
Aldo-keto reductase family 1 member C10101
Prostaglandin G/H synthase 20102
Solute carrier family 22 member 60101
Solute carrier family 22 member 70001
Prostaglandin E2 receptor EP2 subtype0101
Rho-associated protein kinase 20101
Prostaglandin G/H synthase 1 0101
Nicotinate phosphoribosyltransferase0101
Solute carrier family 22 member 80101
Dehydrogenase/reductase SDR family member 90101
P2Y purinoceptor 120101
Cytosolic phospholipase A2 gamma0101
Acetylcholinesterase0505
Cholinesterase0202
nuclear receptor subfamily 1, group I, member 22002
Replicase polyprotein 1ab0101
phosphoethanolamine/phosphocholine phosphatase isoform 10101
serine/threonine-protein kinase PLK12002
Sodium/potassium-transporting ATPase subunit alpha-1 0101
Sodium/potassium-transporting ATPase subunit beta-10101
Amyloid-beta precursor protein1001
Microtubule-associated protein tau0101
Sodium/potassium-transporting ATPase subunit alpha-30101
Sodium/potassium-transporting ATPase subunit beta-20101
Alpha-synuclein1102
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha1001
Fatty acid synthase0202
Sodium/potassium-transporting ATPase subunit alpha-20101
Sodium/potassium-transporting ATPase subunit beta-30101
Sodium/potassium-transporting ATPase subunit gamma0101
WD repeat-containing protein 50101
Histone-lysine N-methyltransferase 2A0101
Sodium/potassium-transporting ATPase subunit alpha-40101
Cytosolic endo-beta-N-acetylglucosaminidase0101
Indoleamine 2,3-dioxygenase 20101
Chain A, ATP-DEPENDENT DNA HELICASE Q13003
dopamine D1 receptor3003
WRN1001
integrase, partial0101
lens epithelium-derived growth factor p750101
pyruvate kinase1001
hexokinase-4 isoform 11001
glucokinase regulatory protein1001
DNA polymerase eta isoform 12002
Polyphenol oxidase 20001
Tyrosine-protein kinase Lck0101
Tyrosine-protein kinase Fyn0101
Polyunsaturated fatty acid lipoxygenase ALOX150202
Tyrosinase0101
Solute carrier family 15 member 10101
SLC16A10 protein0002
Monocarboxylate transporter 100002
phosphoglycerate kinase1001
Free fatty acid receptor 10011
Sterol O-acyltransferase 10101
Trypsin0101
Fatty acid-binding protein, heart0202
Seed linoleate 13S-lipoxygenase-10101
Coagulation factor VII0101
Aromatase0202
Tissue factor0202
Fatty acid-binding protein, adipocyte0202
Tyrosine-protein phosphatase non-receptor type 70101
Sterol O-acyltransferase 10101
Nuclear receptor subfamily 4 group A member 20011
Dual specificity protein phosphatase 30101
Fatty acid-binding protein 50101
Peroxisome proliferator-activated receptor alpha1001
Free fatty acid receptor 40011
cGMP-inhibited 3',5'-cyclic phosphodiesterase B0101
cGMP-inhibited 3',5'-cyclic phosphodiesterase A0101
Type-1 angiotensin II receptor0101
Potassium voltage-gated channel subfamily KQT member 10101
Cysteinyl leukotriene receptor 10101
ClpP1001
Cytochrome P450 1A10101
Myeloperoxidase0202
Cytochrome P450 1A20202
Cytochrome P450 2C11 0101
Ribosyldihydronicotinamide dehydrogenase [quinone]0303
Acetylcholinesterase 0101
Nociceptin receptor0101
Melatonin receptor type 1A0527
Melatonin receptor type 1C0011
Melatonin receptor type 1A0224
Melatonin receptor type 1B0527
Melatonin receptor type 1C0224
Melatonin receptor type 1B0224
Nuclear factor erythroid 2-related factor 20001
Cytochrome P450 1B10101
Carboxylic ester hydrolase 0101
Synaptic vesicular amine transporter0101
Gag-Pol polyprotein0101
muscleblind-like protein 1 isoform 13003
Nuclear receptor subfamily 1 group I member 20033
Glucocorticoid receptor0415
Glycine receptor subunit alpha-10404
Glycine receptor subunit beta0404
Glycine receptor subunit alpha-20404
Glycine receptor subunit alpha-30404
Nuclear receptor subfamily 1 group I member 20011
Beta-1 adrenergic receptor0101
Beta-2 adrenergic receptor0112
Endothelin-1 receptor0101
Angiotensin-converting enzyme0202
5-hydroxytryptamine receptor 3B0202
G-protein coupled receptor 0101
ATP-dependent translocase ABCB10202
ATP-dependent translocase ABCB10202
Opioid receptor, delta 1b 0101
Opioid receptor homologue0101
Acyl-CoA desaturase 10101
Histidine decarboxylase0011
Proteinase-activated receptor 10112
Kappa-type opioid receptor0225
UDP-glucuronosyltransferase 1A30001
Mu-type opioid receptor0226
Nociceptin receptor0101
Mu-type opioid receptor0101
Mu-type opioid receptor0415
Mas-related G-protein coupled receptor member X20011
Mu-type opioid receptor0101
Solute carrier family 22 member 200101
Solute carrier family 22 member 60101
Rap guanine nucleotide exchange factor 44004
Chain B, Exotoxin A0011
Chain B, Exotoxin A0011
Chain B, Exotoxin A0011
Neurotensin receptor type 10011
Neurotensin receptor type 20113
Myelin basic protein0011
Neurotensin receptor type 10112
Neurotensin receptor type 10225
Neurotensin receptor type 20213
Sortilin0101
Neuronal acetylcholine receptor subunit alpha-40213
Transient receptor potential cation channel subfamily A member 10011
Acetylcholine receptor subunit alpha0213
Acetylcholine receptor subunit alpha0213
Acetylcholine receptor subunit beta0213
Acetylcholine receptor subunit gamma0213
Acetylcholine receptor subunit delta0213
Neuronal acetylcholine receptor subunit alpha-30225
Acetylcholine receptor subunit gamma0213
Neuronal acetylcholine receptor subunit alpha-40101
Acetylcholine receptor subunit beta0213
Cytochrome P450 2A60314
Neuronal acetylcholine receptor subunit alpha-20225
Neuronal acetylcholine receptor subunit beta-30225
Neuronal acetylcholine receptor subunit beta-40225
Neuronal acetylcholine receptor subunit beta-20213
Neuronal acetylcholine receptor subunit alpha-50225
Cytochrome P450 2A50101
Acetylcholine receptor subunit beta-like 20202
Neuronal acetylcholine receptor subunit alpha-50011
Neuronal acetylcholine receptor subunit beta-40213
Muscarinic acetylcholine receptor M40101
Neuronal acetylcholine receptor subunit alpha-30213
Neuronal acetylcholine receptor subunit alpha-70224
Neuronal acetylcholine receptor subunit alpha-60225
Neuronal acetylcholine receptor subunit alpha-90225
Neuronal acetylcholine receptor subunit alpha-40213
Neuronal acetylcholine receptor subunit alpha-70202
Acetylcholine-binding protein0112
Acetylcholine receptor subunit epsilon0011
Neuronal acetylcholine receptor subunit beta-30112
Acetylcholine receptor subunit delta0213
Neuronal acetylcholine receptor subunit alpha-20101
Neuronal acetylcholine receptor subunit alpha-60112
Cytochrome P450 2A130112
Neuronal acetylcholine receptor subunit alpha-50202
Liver carboxylesterase B-10101
Transient receptor potential cation channel subfamily A member 10022
Neuronal acetylcholine receptor subunit beta-30202
Neuronal acetylcholine receptor subunit beta-40202
Neuronal acetylcholine receptor subunit alpha-30202
Soluble acetylcholine receptor0101
Neuronal acetylcholine receptor subunit alpha-20202
Neuronal acetylcholine receptor subunit beta-20213
Neuronal acetylcholine receptor subunit alpha-100225
Neuronal acetylcholine receptor subunit alpha-60202
Integrin beta0011
Glycoprotein IIb0011
Voltage-dependent L-type calcium channel subunit beta-40101
Voltage-dependent P/Q-type calcium channel subunit alpha-1A0101
Voltage-dependent calcium channel gamma-3 subunit0101
Voltage-dependent L-type calcium channel subunit beta-30101
Voltage-dependent calcium channel subunit alpha-2/delta-10101
Voltage-dependent calcium channel gamma-7 subunit0101
Voltage-dependent L-type calcium channel subunit beta-10101
Voltage-dependent calcium channel gamma-1 subunit0101
Voltage-dependent L-type calcium channel subunit beta-20101
cAMP-specific 3',5'-cyclic phosphodiesterase 4D0101
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C0101
Voltage-dependent R-type calcium channel subunit alpha-1E0101
Voltage-dependent calcium channel subunit alpha-2/delta-40101
Voltage-dependent calcium channel subunit alpha-2/delta-30101
Voltage-dependent calcium channel gamma-8 subunit0101
Bile acid receptor0202
Voltage-dependent calcium channel gamma-6 subunit0101
Voltage-dependent calcium channel subunit alpha-2/delta-20101
Voltage-dependent calcium channel gamma-4 subunit0101
Voltage-dependent calcium channel gamma-5 subunit0101
Voltage-dependent calcium channel gamma-2 subunit0101
Sodium/iodide cotransporter0101
runt-related transcription factor 1 isoform AML1b1001
core-binding factor subunit beta isoform 21001
DNA repair protein RAD52 homolog0101
interferon gamma precursor0002
Alpha-1A adrenergic receptor0112
Beta-casein0101
Interstitial collagenase0101
Matrix metalloproteinase-90101
Alpha-1B adrenergic receptor0101
Alpha-2A adrenergic receptor0101
Alpha-mannosidase 2C10011
Bromodomain-containing protein 20202
5-hydroxytryptamine receptor 1B0101
Alpha-2B adrenergic receptor0101
3-oxo-5-alpha-steroid 4-dehydrogenase 20101
Type-1 angiotensin II receptor0101
Alpha-2C adrenergic receptor0101
Alpha-2A adrenergic receptor0101
Alpha-2A adrenergic receptor0101
Glucose-6-phosphate 1-dehydrogenase0101
Lanosterol 14-alpha demethylase0101
Chain A, Ferritin light chain0011
Chain A, Ferritin light chain0011
Chain A, Ferritin light chain0011
Chain A, Ferritin light chain0011
Chain A, Ferritin light chain0011
Chain A, Ferritin light chain0011
Chain A, Ferritin light chain0011
Fatty-acid amide hydrolase 10101
UDP-glucuronosyltransferase 1A80001
Solute carrier organic anion transporter family member 2A10101
Solute carrier organic anion transporter family member 2A10102
Solute carrier organic anion transporter family member 2A10101
Solute carrier organic anion transporter family member 2B10001
Dipeptidyl peptidase 40011
Dipeptidyl peptidase 40011
DNA polymerase III, partial1001
ubiquitin-conjugating enzyme E2 N0101
pyruvate kinase PKM isoform b1001
Ornithine decarboxylase1001
Diacylglycerol kinase alpha0101
Carbonic anhydrase 0101
Carbonic anhydrase 0101
Carbonic anhydrase 0101
Carbonic anhydrase0101
Taste receptor type 2 member 310011
Disintegrin and metalloproteinase domain-containing protein 171001
Beta-carbonic anhydrase 10101
Carbonic anhydrase 20101
Carbonic anhydrase, alpha family 0101
Carbonic anhydrase 0101
Delta carbonic anhydrase0101
RmtA0101
Protein arginine N-methyltransferase 10101
Orexin receptor type 10405
Orexin receptor type 20405
Cytochrome P450 2B10101
Amine oxidase [flavin-containing] A 0203
Amine oxidase [flavin-containing] A 0202
Type-1 angiotensin II receptor0101
Amine oxidase [flavin-containing] A0001
Amine oxidase [flavin-containing] B0001
Pyruvate kinase PKM0011
Neutral amino acid transporter A0101
Neutral amino acid transporter B(0)0101
Amino acid transporter0101
Free fatty acid receptor 30011
Orexin receptor type 10101
Orexin receptor type 20101
Substance-K receptor0101
parathyroid hormone/parathyroid hormone-related peptide receptor precursor1001
Steroid 17-alpha-hydroxylase/17,20 lyase0101
Androgen receptor0011
Neuropeptide FF receptor 20001
Muscarinic acetylcholine receptor M20011
Cholesterol 24-hydroxylase0101
Chain X, Thyroid hormone receptor beta-10022
Chain X, Thyroid hormone receptor beta-10022
Transthyretin0103
Thyroid hormone receptor alpha0235
Thyroid hormone receptor beta0235
Proliferating cell nuclear antigen0202
Retinoic acid receptor RXR-alpha0022
Malate dehydrogenase, mitochondrial0101
Solute carrier organic anion transporter family member 4C10102
Monocarboxylate transporter 80001
Solute carrier organic anion transporter family member 1C10001
Thyroid hormone receptor beta0101
Solute carrier organic anion transporter family member 4C10001
Solute carrier organic anion transporter family member 4A10001
Solute carrier organic anion transporter family member 1C10101
Trypanothione reductase0202
Chain A, Trp Rna-binding Attenuation Protein0011
Chain K, Trp Rna-binding Attenuation Protein0011
Chain B, tryptophanyl-tRNA synthetase0011
Chain C, Tryptophanyl-tRNA synthetase II0011
Dihydrofolate reductase0202
Stromelysin-10101
Intestinal-type alkaline phosphatase0101
Indoleamine 2,3-dioxygenase 10102
Tryptophan 2,3-dioxygenase0102
Tryprostatin B synthase0001
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase0011
Phospholipase A-2-activating protein0101
Urease subunit alpha0101
Urease subunit beta0101
Chain A, orotidine 5'-monophosphate decarboxylase0101
Chain B, orotidine 5'-monophosphate decarboxylase0101
Chain A, orotidine 5'-monophosphate decarboxylase0101
Chain A, orotidine monophosphate decarboxylase0101
Chain A, orotidine monophosphate decarboxylase0101
Chain B, orotidine monophosphate decarboxylase0101
Chain B, PyrR bifunctional protein0011
Orotidine 5'-phosphate decarboxylase0101
Uridine 5'-monophosphate synthase0101
UMP-CMP kinase 0001
Orotidine 5'-phosphate decarboxylase 0101
Protein cereblon0101
Protein argonaute-20011
Aldo-keto reductase family 1 member A10101
Liver carboxylesterase 10101
Aldo-keto reductase family 1 member A10101
Aldo-keto reductase family 1 member A10101
Aldo-keto reductase family 1 member B70101
NAD-dependent protein deacylase sirtuin-5, mitochondrial0101
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]