prednisone has been researched along with Noonan Syndrome in 1 studies
Prednisone: A synthetic anti-inflammatory glucocorticoid derived from CORTISONE. It is biologically inert and converted to PREDNISOLONE in the liver.
prednisone : A synthetic glucocorticoid drug that is particularly effective as an immunosuppressant, and affects virtually all of the immune system. Prednisone is a prodrug that is converted by the liver into prednisolone (a beta-hydroxy group instead of the oxo group at position 11), which is the active drug and also a steroid.
Noonan Syndrome: A genetically heterogeneous, multifaceted disorder characterized by short stature, webbed neck, ptosis, skeletal malformations, hypertelorism, hormonal imbalance, CRYPTORCHIDISM, multiple cardiac abnormalities (most commonly including PULMONARY VALVE STENOSIS), and some degree of INTELLECTUAL DISABILITY. The phenotype bears similarities to that of TURNER SYNDROME that occurs only in females and has its basis in a 45, X karyotype abnormality. Noonan syndrome occurs in both males and females with a normal karyotype (46,XX and 46,XY). Mutations in a several genes (PTPN11, KRAS, SOS1, NF1 and RAF1) have been associated the NS phenotype. Mutations in PTPN11 are the most common. LEOPARD SYNDROME, a disorder that has clinical features overlapping those of Noonan Syndrome, is also due to mutations in PTPN11. In addition, there is overlap with the syndrome called neurofibromatosis-Noonan syndrome due to mutations in NF1.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To describe a case of spontaneous chylothorax in a child with Noonan syndrome successfully treated with prednisone." | 8.78 | Spontaneous chylothorax in Noonan syndrome. Treatment with prednisone. ( Campbell, D; Goens, MB; Wiggins, JW, 1992) |
| "To describe a case of spontaneous chylothorax in a child with Noonan syndrome successfully treated with prednisone." | 4.78 | Spontaneous chylothorax in Noonan syndrome. Treatment with prednisone. ( Campbell, D; Goens, MB; Wiggins, JW, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Goens, MB | 1 |
| Campbell, D | 1 |
| Wiggins, JW | 1 |
1 review available for prednisone and Noonan Syndrome
| Article | Year |
|---|---|
Spontaneous chylothorax in Noonan syndrome. Treatment with prednisone.
Topics: Chylothorax; Drainage; Female; Humans; Infant; Noonan Syndrome; Prednisone; Radiography | 1992 |