methanol has been researched along with Acute Q Fever in 9 studies
Methanol: A colorless, flammable liquid used in the manufacture of FORMALDEHYDE and ACETIC ACID, in chemical synthesis, antifreeze, and as a solvent. Ingestion of methanol is toxic and may cause blindness.
primary alcohol : A primary alcohol is a compound in which a hydroxy group, -OH, is attached to a saturated carbon atom which has either three hydrogen atoms attached to it or only one other carbon atom and two hydrogen atoms attached to it.
methanol : The primary alcohol that is the simplest aliphatic alcohol, comprising a methyl and an alcohol group.
| Excerpt | Relevance | Reference |
|---|---|---|
| " None of those receiving the 30- or 60-micrograms CMR dose and none of the placebo recipients experienced any adverse effects." | 2.67 | Safety and immunogenicity in human volunteers of a chloroform-methanol residue vaccine for Q fever. ( Fries, LF; Waag, DM; Williams, JC, 1993) |
| "Human Q fever is recognized as a worldwide public health problem." | 1.51 | Enhanced protection against Q fever in BALB/c mice elicited by immunization of chloroform-methanol residue of Coxiella burnetii via intratracheal inoculation. ( Dai, L; Du, Z; Feng, J; Fu, M; Hu, X; Jiao, J; Lu, Z; Luo, W; Wen, B; Xiong, X; Yu, Y; Zhao, Z; Zhou, D, 2019) |
| "burnetii organisms, a safer Q fever vaccine." | 1.42 | Chloroform-Methanol Residue of Coxiella burnetii Markedly Potentiated the Specific Immunoprotection Elicited by a Recombinant Protein Fragment rOmpB-4 Derived from Outer Membrane Protein B of Rickettsia rickettsii in C3H/HeN Mice. ( Gong, W; Jiao, J; Wang, P; Wen, B; Xiong, X; Yang, X, 2015) |
| "While phase I cellular Q fever vaccines are efficacious in humans, vaccination of immune individuals may result in sterile abscesses and granulomas." | 1.30 | Comparative efficacy of a Coxiella burnetii chloroform:methanol residue (CMR) vaccine and a licensed cellular vaccine (Q-Vax) in rodents challenged by aerosol. ( England, MJ; Pitt, ML; Waag, DM, 1997) |
| "In humans who suffered from Q fever one year ago, higher proportion of positive skin test (ST) reactions and antibody recalls with higher mean geometric titres (MGT) of phase II MA antibodies was noticed following intradermal administration of TCAE than of TCAE-CM." | 1.27 | Antigenicity of chloroform-methanol-treated Coxiella burnetii preparations. ( Brezina, R; Kazár, J; Lisák, V; Schramek, S, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (22.22) | 18.7374 |
| 1990's | 3 (33.33) | 18.2507 |
| 2000's | 2 (22.22) | 29.6817 |
| 2010's | 2 (22.22) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Feng, J | 1 |
| Hu, X | 1 |
| Fu, M | 1 |
| Dai, L | 1 |
| Yu, Y | 1 |
| Luo, W | 1 |
| Zhao, Z | 1 |
| Lu, Z | 1 |
| Du, Z | 1 |
| Zhou, D | 1 |
| Wen, B | 2 |
| Jiao, J | 2 |
| Xiong, X | 2 |
| Gong, W | 1 |
| Wang, P | 1 |
| Yang, X | 1 |
| Ruble, DL | 1 |
| Elliott, JJ | 1 |
| Waag, DM | 6 |
| Jaax, GP | 1 |
| Fries, LF | 1 |
| Williams, JC | 2 |
| England, MJ | 2 |
| Pitt, ML | 2 |
| Wilhelmsen, CL | 1 |
| Tammariello, RF | 1 |
| Byrne, WR | 1 |
| Gibbs, P | 1 |
| Banfield, CM | 1 |
| Kazár, J | 1 |
| Schramek, S | 1 |
| Lisák, V | 1 |
| Brezina, R | 1 |
| Damrow, TA | 1 |
| Amano, K | 1 |
1 trial available for methanol and Acute Q Fever
| Article | Year |
|---|---|
Safety and immunogenicity in human volunteers of a chloroform-methanol residue vaccine for Q fever.
Topics: Antibodies, Bacterial; Bacterial Vaccines; Chloroform; Coxiella burnetii; Dose-Response Relationship | 1993 |
8 other studies available for methanol and Acute Q Fever
| Article | Year |
|---|---|
Enhanced protection against Q fever in BALB/c mice elicited by immunization of chloroform-methanol residue of Coxiella burnetii via intratracheal inoculation.
Topics: Administration, Inhalation; Animals; Antibodies, Bacterial; Bacterial Load; Bacterial Vaccines; Bron | 2019 |
Chloroform-Methanol Residue of Coxiella burnetii Markedly Potentiated the Specific Immunoprotection Elicited by a Recombinant Protein Fragment rOmpB-4 Derived from Outer Membrane Protein B of Rickettsia rickettsii in C3H/HeN Mice.
Topics: Animals; Antibodies, Bacterial; Antigens, Bacterial; Bacterial Outer Membrane Proteins; Bacterial Va | 2015 |
A refined guinea pig model for evaluating delayed-type hypersensitivity reactions caused by Q fever vaccines.
Topics: Adjuvants, Immunologic; Animals; Bacterial Vaccines; Chloroform; Coxiella burnetii; Disease Models, | 1994 |
Comparative efficacy of a Coxiella burnetii chloroform:methanol residue (CMR) vaccine and a licensed cellular vaccine (Q-Vax) in rodents challenged by aerosol.
Topics: Aerosols; Animals; Bacterial Vaccines; Chloroform; Coxiella burnetii; Disease Models, Animal; Female | 1997 |
Guinea pig abscess/hypersensitivity model for study of adverse vaccination reactions induced by use of Q fever vaccines.
Topics: Abscess; Aerosols; Animals; Bacterial Vaccines; Chloroform; Coxiella burnetii; Erythema; Female; Gui | 2000 |
Comparative efficacy and immunogenicity of Q fever chloroform:methanol residue (CMR) and phase I cellular (Q-Vax) vaccines in cynomolgus monkeys challenged by aerosol.
Topics: Administration, Inhalation; Aerosols; Animals; Antibodies, Bacterial; Bacterial Vaccines; Chloroform | 2002 |
Antigenicity of chloroform-methanol-treated Coxiella burnetii preparations.
Topics: Animals; Antibodies, Bacterial; Antigens, Bacterial; Bacterial Vaccines; Cattle; Chloroform; Coxiell | 1987 |
Characterization of a phase I Coxiella burnetii chloroform-methanol residue vaccine that induces active immunity against Q fever in C57BL/10 ScN mice.
Topics: Animals; Antibodies, Bacterial; Bacterial Vaccines; Chloroform; Coxiella; Lymphocyte Activation; Lym | 1986 |