ofloxacin has been researched along with Acute Q Fever in 14 studies
Ofloxacin: A synthetic fluoroquinolone antibacterial agent that inhibits the supercoiling activity of bacterial DNA GYRASE, halting DNA REPLICATION.
9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid : An oxazinoquinoline that is 2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinolin-7-one substituted by methyl, carboxy, fluoro, and 4-methylpiperazin-1-yl groups at positions 3, 6, 9, and 10, respectively.
ofloxacin : A racemate comprising equimolar amounts of levofloxacin and dextrofloxacin. It is a synthetic fluoroquinolone antibacterial agent which inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The present article is a study of the in vitro susceptibility of eight Greek Coxiella burnetii isolates, derived from patients with acute Q fever, and two reference strains of Coxiella burnetii to tigecycline." | 3.75 | Bacteriostatic and bactericidal activities of tigecycline against Coxiella burnetii and comparison with those of six other antibiotics. ( Gikas, A; Psaroulaki, A; Spyridaki, I; Tselentis, Y; Vranakis, I, 2009) |
| "The first-line therapy for acute Q fever is 14 to 21 days of doxycycline, or fluoroquinolones such as ofloxacin or pefloxacin." | 3.73 | [Present possibilities of Q fever therapy.]. ( Cisláková, L; Dorko, E; Kizek, P, 2006) |
| "Hemophagocytic syndrome is a rare complication of acute Q fever." | 2.43 | Acute Q fever with hemophagocytic syndrome: case report and literature review. ( Chang, K; Chen, TC; Chen, YH; Hsieh, HC; Lin, SF; Lin, WR; Liu, YC; Lu, PL; Tsai, JJ; Yang, WC, 2006) |
| "We found serological evidence of acute murine typhus in 21 of 125 (17%) patients, with 12 of 21 (57%) patients polymerase chain reaction (PCR)-positive for Rickettsia typhi." | 1.42 | Undifferentiated febrile illness in Kathmandu, Nepal. ( Arjyal, A; Baker, S; Basnyat, B; Blacksell, SD; Day, N; Dolecek, C; Dongol, S; Farrar, J; Giri, A; Karkey, A; Paris, DH; Thompson, CN; Thwaites, G, 2015) |
| "burnetii) is involved in chronic fatigue syndrome (CFS), we administered tetracycline antibiotics to subjects with CFS, and followed changes in clinical symptoms, PCR findings, and C." | 1.33 | Treatment of chronic fatigue syndrome with antibiotics: pilot study assessing the involvement of Coxiella burnetii infection. ( Arakawa, Y; Arashima, Y; Ikeda, T; Iwakami, E; Kato, K; Komiya, T; Matsukawa, Y; Oshida, S, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (14.29) | 18.7374 |
| 1990's | 4 (28.57) | 18.2507 |
| 2000's | 6 (42.86) | 29.6817 |
| 2010's | 2 (14.29) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Spyridaki, I | 1 |
| Psaroulaki, A | 1 |
| Vranakis, I | 1 |
| Tselentis, Y | 1 |
| Gikas, A | 1 |
| Thompson, CN | 1 |
| Blacksell, SD | 1 |
| Paris, DH | 1 |
| Arjyal, A | 1 |
| Karkey, A | 1 |
| Dongol, S | 1 |
| Giri, A | 1 |
| Dolecek, C | 1 |
| Day, N | 1 |
| Baker, S | 1 |
| Thwaites, G | 1 |
| Farrar, J | 1 |
| Basnyat, B | 1 |
| Carrascosa, MF | 1 |
| Pascual Velasco, F | 1 |
| Gómez Izquierdo, R | 1 |
| Salcines-Caviedes, JR | 1 |
| Gómez Amigo, V | 1 |
| Canga-Villegas, AM | 1 |
| Healy, B | 1 |
| Llewelyn, M | 1 |
| Westmoreland, D | 1 |
| Lloyd, G | 1 |
| Brown, N | 1 |
| Iwakami, E | 1 |
| Arashima, Y | 1 |
| Kato, K | 1 |
| Komiya, T | 1 |
| Matsukawa, Y | 1 |
| Ikeda, T | 1 |
| Arakawa, Y | 1 |
| Oshida, S | 1 |
| Dorko, E | 1 |
| Cisláková, L | 1 |
| Kizek, P | 1 |
| Chen, TC | 1 |
| Chang, K | 1 |
| Lu, PL | 1 |
| Liu, YC | 1 |
| Chen, YH | 1 |
| Hsieh, HC | 1 |
| Yang, WC | 1 |
| Lin, WR | 1 |
| Tsai, JJ | 1 |
| Lin, SF | 1 |
| Fradi, I | 1 |
| Drissa, MA | 1 |
| Cheour, M | 1 |
| Drissa, H | 1 |
| De Seze, J | 1 |
| Caparros-Lefebvre, D | 1 |
| Levêque, P | 1 |
| Petit, H | 1 |
| Bernard, E | 1 |
| Carles, M | 1 |
| Laffont, C | 1 |
| Durant, J | 1 |
| Dellamonica, P | 1 |
| Kaplanski, G | 1 |
| Granel, B | 1 |
| Vaz, T | 1 |
| Durand, JM | 1 |
| Raoult, D | 1 |
| Houpikian, P | 1 |
| Tissot Dupont, H | 1 |
| Riss, JM | 1 |
| Arditi-Djiane, J | 1 |
| Brouqui, P | 1 |
| Raffi, F | 1 |
| Bertrand, A | 1 |
| Janbon, F | 1 |
| Jonquet, O | 1 |
| Reynes, J | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Parallel Group, Double Blinded, 1:1, Randomized Controlled Phase III Trial of Co-trimoxazole Versus Azithromycin for the Treatment of Undifferentiated Fever In Nepal[NCT02773407] | Phase 3 | 330 participants (Actual) | Interventional | 2016-05-23 | Completed | ||
| Clinical Trial Evaluating Safety and Efficacy of Hydroxychloroquine and Nitazoxanide Combination as Adjuvant Therapy in Covid-19 Newly Diagnosed Egyptian Patients: A Tanta University Hope[NCT04361318] | Phase 2/Phase 3 | 100 participants (Anticipated) | Interventional | 2020-05-31 | Not yet recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for ofloxacin and Acute Q Fever
| Article | Year |
|---|---|
Acute Q fever with hemophagocytic syndrome: case report and literature review.
Topics: Adult; Anti-Bacterial Agents; Bone Marrow Examination; Coxiella burnetii; Disseminated Intravascular | 2006 |
13 other studies available for ofloxacin and Acute Q Fever
| Article | Year |
|---|---|
Bacteriostatic and bactericidal activities of tigecycline against Coxiella burnetii and comparison with those of six other antibiotics.
Topics: Animals; Anti-Bacterial Agents; Chlorocebus aethiops; Coxiella burnetii; Humans; Microbial Sensitivi | 2009 |
Undifferentiated febrile illness in Kathmandu, Nepal.
Topics: Anti-Bacterial Agents; Fever; Fluoroquinolones; Gatifloxacin; Humans; Nepal; Ofloxacin; Prospective | 2015 |
Acute Q fever myocarditis: thinking about a life-threatening but potentially curable condition.
Topics: Anti-Bacterial Agents; Humans; Magnetic Resonance Imaging; Male; Myocarditis; Ofloxacin; Q Fever; Yo | 2012 |
The value of follow-up after acute Q fever infection.
Topics: Anti-Bacterial Agents; Antibodies, Bacterial; Chronic Disease; Complement Fixation Tests; Coxiella b | 2006 |
Treatment of chronic fatigue syndrome with antibiotics: pilot study assessing the involvement of Coxiella burnetii infection.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Antibodies, Bacterial; Child; Cox | 2005 |
[Present possibilities of Q fever therapy.].
Topics: Coxiella burnetii; Doxycycline; Humans; Hyperthermia, Induced; Ofloxacin; Q Fever | 2006 |
[Q fever endocarditis: a case report].
Topics: Adult; Anti-Bacterial Agents; Aortic Valve; Aortic Valve Stenosis; Doxycycline; Drug Therapy, Combin | 2006 |
[Confusion syndrome revealing Q fever].
Topics: Aged; Confusion; Humans; Male; Ofloxacin; Q Fever | 1995 |
Guillain-Barré syndrome associated with acute Q fever.
Topics: Adult; Coxiella burnetii; Female; Humans; Ofloxacin; Polyradiculoneuropathy; Q Fever | 1994 |
Jarisch-Herxheimer reaction complicating the treatment of chronic Q fever endocarditis: elevated TNFalpha and IL-6 serum levels.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Chronic Disease; Coxiella burnetii; Doxycycline; Drug | 1998 |
Treatment of Q fever endocarditis: comparison of 2 regimens containing doxycycline and ofloxacin or hydroxychloroquine.
Topics: Adult; Anti-Bacterial Agents; Anti-Infective Agents; Doxycycline; Drug Therapy, Combination; Endocar | 1999 |
Q-fever endocarditis.
Topics: Endocarditis, Bacterial; Female; Humans; Middle Aged; Ofloxacin; Pulmonary Fibrosis; Q Fever | 1989 |
[Rickettsiaceae infections and fluoroquinolones].
Topics: Administration, Oral; Adult; Aged; Anti-Infective Agents; Boutonneuse Fever; Drug Evaluation; Drug T | 1988 |