n(1)-methylnicotinamide has been researched along with Pellagra in 5 studies
N(1)-methylnicotinamide: RN given refers to parent cpd
1-methylnicotinamide : A pyridinium ion comprising nicotinamide having a methyl group at the 1-position. It is a metabolite of nicotinamide which was initially considered to be biologically inactive but has emerged as an anti-thrombotic and anti-inflammatory agent.
Pellagra: A disease due to deficiency of NIACIN, a B-complex vitamin, or its precursor TRYPTOPHAN. It is characterized by scaly DERMATITIS which is often associated with DIARRHEA and DEMENTIA (the three D's).
| Excerpt | Relevance | Reference |
|---|---|---|
| "The effect of the administration of oestrone sulphate on tryptophan metabolism has been assessed in rats in order to determine whether and to what extent inhibition of tryptophan metabolism by oestrogens may be a factor in the aetiology of pellagra, and might explain the reported twofold excess of females over males in many outbreaks of pellagra." | 7.67 | Inhibition of tryptophan metabolism by oestrogens in the rat: a factor in the aetiology of pellagra. ( Bender, DA; Totoe, L, 1984) |
| "The effect of the administration of oestrone sulphate on tryptophan metabolism has been assessed in rats in order to determine whether and to what extent inhibition of tryptophan metabolism by oestrogens may be a factor in the aetiology of pellagra, and might explain the reported twofold excess of females over males in many outbreaks of pellagra." | 3.67 | Inhibition of tryptophan metabolism by oestrogens in the rat: a factor in the aetiology of pellagra. ( Bender, DA; Totoe, L, 1984) |
| "Flaky paint dermatosis, characterized by extensive, often bilateral areas of flaking and pigmentation, mostly in sun unexposed areas is considered a feature of kwashiorkor in both children and adults, and must be differentiated from other dermatosis, including chapped and xerotica skin, and pellagra." | 1.42 | Niacin metabolism and indoleamine 2,3-dioxygenase activation in malnourished patients with flaky paint dermatosis. ( da Cunha, DF; Maltos, AL; Monteiro, MC; Moraes, GV; Portari, GV; Vannucchi, H, 2015) |
| " Nor did their 14CO2 production differ after intraperitoneal dosing with [methylene-14C]tryptophan." | 1.27 | Leucine excess and niacin status in rats. ( Carpenter, KJ; Cook, NE, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (60.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Maltos, AL | 1 |
| Portari, GV | 1 |
| Moraes, GV | 1 |
| Monteiro, MC | 1 |
| Vannucchi, H | 1 |
| da Cunha, DF | 1 |
| NAJJAR, VA | 1 |
| DEAL, CC | 1 |
| Creeke, PI | 1 |
| Dibari, F | 1 |
| Cheung, E | 1 |
| van den Briel, T | 1 |
| Kyroussis, E | 1 |
| Seal, AJ | 1 |
| Bender, DA | 1 |
| Totoe, L | 1 |
| Cook, NE | 1 |
| Carpenter, KJ | 1 |
5 other studies available for n(1)-methylnicotinamide and Pellagra
| Article | Year |
|---|---|
Niacin metabolism and indoleamine 2,3-dioxygenase activation in malnourished patients with flaky paint dermatosis.
Topics: Acute-Phase Reaction; Adult; Aged; C-Reactive Protein; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; | 2015 |
The antipellagra action of N1-methylnicotinamide.
Topics: Humans; Niacin; Niacinamide; Nicotinic Acids; Pellagra | 1947 |
Whole blood NAD and NADP concentrations are not depressed in subjects with clinical pellagra.
Topics: Adolescent; Adult; Female; Humans; Male; Middle Aged; NAD; NADP; Niacinamide; Pellagra; Pyridones; S | 2007 |
Inhibition of tryptophan metabolism by oestrogens in the rat: a factor in the aetiology of pellagra.
Topics: Animals; Castration; Estrone; Female; Liver; NAD; NADP; Niacinamide; Pellagra; Rats; Rats, Inbred St | 1984 |
Leucine excess and niacin status in rats.
Topics: Animals; Body Weight; Diet; Edible Grain; India; Leucine; Liver; Male; Niacin; Niacinamide; Nicotina | 1987 |