fluorouracil has been researched along with Pellagra in 3 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
Pellagra: A disease due to deficiency of NIACIN, a B-complex vitamin, or its precursor TRYPTOPHAN. It is characterized by scaly DERMATITIS which is often associated with DIARRHEA and DEMENTIA (the three D's).
| Excerpt | Relevance | Reference |
|---|---|---|
| "The development of pellagra in a patient treated with 5-fluorouracil for malignant disease is reported." | 7.68 | Pellagra secondary to 5-fluorouracil. ( Begent, RH; Dooley, JS; Ostlere, LS; Rustin, MH; Stevens, HP, 1993) |
| "The development of pellagra in a patient treated with 5-fluorouracil for malignant disease is reported." | 3.68 | Pellagra secondary to 5-fluorouracil. ( Begent, RH; Dooley, JS; Ostlere, LS; Rustin, MH; Stevens, HP, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (66.67) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Stevens, HP | 1 |
| Ostlere, LS | 1 |
| Begent, RH | 1 |
| Dooley, JS | 1 |
| Rustin, MH | 1 |
| Stratigos, JD | 1 |
| Katsambas, A | 1 |
| Castiello, RJ | 1 |
| Lynch, PJ | 1 |
3 other studies available for fluorouracil and Pellagra
| Article | Year |
|---|---|
Pellagra secondary to 5-fluorouracil.
Topics: Aged; Biliary Tract Neoplasms; Fluorouracil; Humans; Liver Neoplasms; Male; Nicotinic Acids; Pellagr | 1993 |
Pellagra: a still existing disease.
Topics: Alcoholism; Diet; Fluorouracil; Humans; Intestinal Absorption; Isoniazid; Mercaptopurine; Nicotinic | 1977 |
Pellagra and the carcinoid syndrome.
Topics: Digitalis Glycosides; Diuretics; Female; Fluorouracil; Humans; Malignant Carcinoid Syndrome; Middle | 1972 |