valproic acid has been researched along with Pellagra in 2 studies
Valproic Acid: A fatty acid with anticonvulsant and anti-manic properties that is used in the treatment of EPILEPSY and BIPOLAR DISORDER. The mechanisms of its therapeutic actions are not well understood. It may act by increasing GAMMA-AMINOBUTYRIC ACID levels in the brain or by altering the properties of VOLTAGE-GATED SODIUM CHANNELS.
valproic acid : A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.
Pellagra: A disease due to deficiency of NIACIN, a B-complex vitamin, or its precursor TRYPTOPHAN. It is characterized by scaly DERMATITIS which is often associated with DIARRHEA and DEMENTIA (the three D's).
| Excerpt | Relevance | Reference |
|---|---|---|
| "The case of a mentally handicapped female patient is presented who developed typical pellagra with dermatitis, diarrhoea and mental alteration following a long-term antiepileptic treatment with phenytoin, ethosuximide and valproic acid." | 3.68 | [Pellagra in anticonvulsive therapy]. ( Bartels, H; Hebestreit, H; Mingers, AM; Pannenbecker, J, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (50.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gillman, MA | 1 |
| Sandyk, R | 1 |
| Hebestreit, H | 1 |
| Pannenbecker, J | 1 |
| Mingers, AM | 1 |
| Bartels, H | 1 |
2 other studies available for valproic acid and Pellagra
| Article | Year |
|---|---|
Nicotinic acid deficiency induced by sodium valproate.
Topics: Child; Humans; Male; Niacin; Pellagra; Valproic Acid | 1984 |
[Pellagra in anticonvulsive therapy].
Topics: Adult; Anticonvulsants; Drug Therapy, Combination; Epilepsy; Ethosuximide; Female; Humans; Intellect | 1990 |