Page last updated: 2024-10-19

kynurenine and Pellagra

kynurenine has been researched along with Pellagra in 16 studies

Kynurenine: A metabolite of the essential amino acid tryptophan metabolized via the tryptophan-kynurenine pathway.
kynurenine : A ketone that is alanine in which one of the methyl hydrogens is substituted by a 2-aminobenzoyl group.

Pellagra: A disease due to deficiency of NIACIN, a B-complex vitamin, or its precursor TRYPTOPHAN. It is characterized by scaly DERMATITIS which is often associated with DIARRHEA and DEMENTIA (the three D's).

Research Excerpts

ExcerptRelevanceReference
" The eruption was diagnosed as a pellagra-like syndrome on tryptophan loading test disorders without any other cause of sun sensitivity."3.66[Photosensitivity and disturbances of tryptophan metabolism (kynurenin pathway) (author's transl)]. ( Bousquet, B; Civatte, J; Dreux, C; Escande, C; Garnier, JP; Ramelet, AA; Sohier, J, 1979)
"Flaky paint dermatosis, characterized by extensive, often bilateral areas of flaking and pigmentation, mostly in sun unexposed areas is considered a feature of kwashiorkor in both children and adults, and must be differentiated from other dermatosis, including chapped and xerotica skin, and pellagra."1.42Niacin metabolism and indoleamine 2,3-dioxygenase activation in malnourished patients with flaky paint dermatosis. ( da Cunha, DF; Maltos, AL; Monteiro, MC; Moraes, GV; Portari, GV; Vannucchi, H, 2015)

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-199014 (87.50)18.7374
1990's1 (6.25)18.2507
2000's0 (0.00)29.6817
2010's1 (6.25)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Maltos, AL1
Portari, GV1
Moraes, GV1
Monteiro, MC1
Vannucchi, H1
da Cunha, DF1
DELAEY, P1
HOOFT, C1
TIMMERMANS, J1
SNOECK, J1
Khattab, M1
Abul-Fadl, MA1
Khalafallah, AS1
Hamza, SM1
Magboul, BI1
Bender, DA3
Russell-Jones, R1
Sohier, J1
Bousquet, B1
Garnier, JP1
Escande, C1
Ramelet, AA1
Dreux, C1
Civatte, J1
Leklem, JE3
Brown, RR3
Hankes, LV3
Jansen, CR1
Brune, GG1
Brune, RM1
Wiskemann, A1
Mekel, RC2
Calandra, P3
Binazzi, M1
Abdel-Daim, MH1
Kholief, TS1
Konbar, AA1
Abdel-Tawab, GA1
Mainardi, L1
Bissanti, A1

Other Studies

16 other studies available for kynurenine and Pellagra

ArticleYear
Niacin metabolism and indoleamine 2,3-dioxygenase activation in malnourished patients with flaky paint dermatosis.
    Nutrition (Burbank, Los Angeles County, Calif.), 2015, Volume: 31, Issue:6

    Topics: Acute-Phase Reaction; Adult; Aged; C-Reactive Protein; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase;

2015
BIOCHEMICAL ASPECTS OF THE HARTNUP DISEASE. II. SOME OBSERVATIONS ON RATS ABOUT TRYPTOPHAN METABOLISM.
    Annales paediatrici. International review of pediatrics, 1964, Volume: 202

    Topics: Child; Clinical Enzyme Tests; Hartnup Disease; Humans; Indican; Indoles; Kidney; Kynurenine; Metabol

1964
Studies on the urinary excretion of certain tryptophan metabolites in Egyptian pellagrins.
    The Journal of tropical medicine and hygiene, 1967, Volume: 70, Issue:4

    Topics: Adult; Egypt; Humans; Indoleacetic Acids; Kynurenic Acid; Kynurenine; ortho-Aminobenzoates; Pellagra

1967
The effects of a dietary excess of leucine on the synthesis of nicotinamide nucleotides in the rat.
    The British journal of nutrition, 1983, Volume: 49, Issue:3

    Topics: Animals; Diet; Enzyme Activation; Hydrolases; Kynurenine; Leucine; Liver; Male; NADP; Niacin; Niacin

1983
Isoniazid-induced pellagra despite vitamin-B6 supplementation.
    Lancet (London, England), 1979, Nov-24, Volume: 2, Issue:8152

    Topics: Adult; Behcet Syndrome; Female; Humans; Isoniazid; Kynurenine; Mixed Function Oxygenases; Nicotinic

1979
[Photosensitivity and disturbances of tryptophan metabolism (kynurenin pathway) (author's transl)].
    Annales de dermatologie et de venereologie, 1979, Volume: 106, Issue:5

    Topics: Aged; Animals; Female; Humans; Kynurenine; Pellagra; Photosensitivity Disorders; Rats; Tryptophan

1979
A mechanism for the formation in vivo of the 8-methyl ether of xanthurenic acid in humans.
    Biochemical medicine, 1975, Volume: 12, Issue:1

    Topics: Adult; Female; Humans; Kynurenic Acid; Kynurenine; Male; Methionine; Methyl Ethers; Middle Aged; Pel

1975
Inhibition of tryptophan----niacin metabolism by dietary leucine and by leucine and 2-oxo-isocaproate in vitro.
    Advances in experimental medicine and biology, 1991, Volume: 294

    Topics: Animals; Cells, Cultured; Depression, Chemical; Dietary Proteins; Keto Acids; Kynurenine; Leucine; L

1991
[Tryptophan metabolism in patients with pellagra].
    Archiv fur dermatologische Forschung, 1970, Volume: 240, Issue:1

    Topics: Acetaminophen; Administration, Oral; Adult; Aged; Child, Preschool; Female; Hartnup Disease; Humans;

1970
Tryptophan metabolism in patients with pellagra: problem of vitamin B 6 enzyme activity and feedback control of tryptophan pyrrolase enzyme.
    The American journal of clinical nutrition, 1971, Volume: 24, Issue:6

    Topics: Black or African American; Black People; Feedback; Female; Humans; Kynurenine; Male; Niacinamide; Ni

1971
Tryptophan metabolism in man, rat and pig. Determination of tryptophan-pyrrolase and kinureninase in liver.
    Acta vitaminologica et enzymologica, 1972, Volume: 26, Issue:5

    Topics: Adult; Animals; Dicarboxylic Acids; Erythema; Female; Humans; Hydrolases; Kynurenine; Lichen Planus;

1972
Identification of an error in the tryptophan--niacin pathway in carriers of some dermatoses conditioned or aggravated by sunlight.
    Archiv fur klinische und experimentelle Dermatologie, 1971, Volume: 239, Issue:4

    Topics: Adult; Aged; Animals; Atrophy; Cataract; Female; Gastric Juice; Humans; Hydrolases; Kynurenine; Ligh

1971
Tryptophan: abnormal metabolism in pellagra patients.
    Metabolism: clinical and experimental, 1970, Volume: 19, Issue:6

    Topics: Aminohippuric Acids; Black People; Female; Glucuronates; Humans; Kynurenine; Pellagra; South Africa;

1970
The functional capacity of the tryptophan-niacin pathway in pellagrous children.
    Transactions of the Royal Society of Tropical Medicine and Hygiene, 1970, Volume: 64, Issue:3

    Topics: Amines; Aminohippuric Acids; Child; Child, Preschool; Glucuronates; Humans; Kynurenic Acid; Kynureni

1970
[New viewpoints on the pathogenesis of pellagra].
    Giornale italiano di dermatolotia. Minerva dermatologica, 1970, Volume: 45, Issue:3

    Topics: Humans; Kynurenine; Metabolic Diseases; Pellagra; Pyridoxine; Riboflavin; Tryptophan

1970
[Various current findings in the problem of pellagra].
    Acta vitaminologica et enzymologica, 1968, Volume: 22, Issue:3

    Topics: Alcoholism; Deficiency Diseases; Diet; Feeding Behavior; Hartnup Disease; Humans; Isoniazid; Isonico

1968