pyridoxine has been researched along with Pellagra in 25 studies
4,5-bis(hydroxymethyl)-2-methylpyridin-3-ol: structure in first source
vitamin B6 : Any member of the group of pyridines that exhibit biological activity against vitamin B6 deficiency. Vitamin B6 deficiency is associated with microcytic anemia, electroencephalographic abnormalities, dermatitis with cheilosis (scaling on the lips and cracks at the corners of the mouth) and glossitis (swollen tongue), depression and confusion, and weakened immune function. Vitamin B6 consists of the vitamers pyridoxine, pyridoxal, and pyridoxamine and their respective 5'-phosphate esters (and includes their corresponding ionized and salt forms).
Pellagra: A disease due to deficiency of NIACIN, a B-complex vitamin, or its precursor TRYPTOPHAN. It is characterized by scaly DERMATITIS which is often associated with DIARRHEA and DEMENTIA (the three D's).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Although pellagra is a recognized complication of isoniazid therapy, the diagnosis may be overlooked or delayed--sometimes with life-threatening consequences." | 7.70 | Isoniazid induced pellagra despite pyridoxine supplementation. ( Basarab, T; Darvay, A; McGregor, JM; Russell-Jones, R, 1999) |
| "After reviewing the literature on nicotinic acid in the treatment of schizophrenia, the authors present the results of the Canadian collaborative study." | 5.04 | Nicotinic acid in the treatment of schizophrenias. Practical and theoretical considerations. ( Ban, TA, 1975) |
| "Although pellagra is a recognized complication of isoniazid therapy, the diagnosis may be overlooked or delayed--sometimes with life-threatening consequences." | 3.70 | Isoniazid induced pellagra despite pyridoxine supplementation. ( Basarab, T; Darvay, A; McGregor, JM; Russell-Jones, R, 1999) |
| "Distrubances in the tryptophan-niacin pathway seen in endemic pellagra among sorghum eaters have been ascribed to high dietary intake of leucine." | 3.65 | Effect of vitamin B6 on leucine-induced changes in human subjects. ( Krishnaswamy, K; Raghuram, TC; Rao, SB; Srikantia, SG, 1976) |
| "A 11-year-old girl suffering from grand mal epilepsy underwent antiepileptic therapy with carbamazepine (600 mg/daily)." | 1.30 | [Dose-dependent pellagroid skin reaction caused by carbamazepine]. ( Heyer, G; Schell, H; Simon, M, 1998) |
| "The clinical features included confusion and/or clouding of consciousness, marked oppositional hypertonus ('gegenhalten') and myoclonus." | 1.27 | The clinical spectrum of alcoholic pellagra encephalopathy. A retrospective analysis of 22 cases studied pathologically. ( Buge, A; Castaigne, P; Goulon, M; Hausser-Hauw, C; Hauw, JJ; Laplane, D; Lhermitte, F; Serdaru, M, 1988) |
| "The primary hepatoma group had 4 with ETK coenzyme effects above 30%, and 3 of the 4 had low level urinary thiamine excretions." | 1.26 | Effects of vitamins B1, B2, B6 and C on erythrocyte enzymes in South African Bantu. ( Hankes, L; Oosthuysen, AW; Yeh, J, 1982) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 22 (88.00) | 18.7374 |
| 1990's | 2 (8.00) | 18.2507 |
| 2000's | 1 (4.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Okan, G | 1 |
| Yaylaci, S | 1 |
| Alzafer, S | 1 |
| HAMMOUDA, M | 1 |
| SIDKY, M | 1 |
| AFONSKY, D | 1 |
| WERTMAN, K | 1 |
| SARANDRIA, JL | 1 |
| Yeh, J | 1 |
| Hankes, L | 1 |
| Oosthuysen, AW | 1 |
| Heyer, G | 1 |
| Simon, M | 1 |
| Schell, H | 1 |
| Darvay, A | 1 |
| Basarab, T | 1 |
| McGregor, JM | 1 |
| Russell-Jones, R | 2 |
| Ban, TA | 1 |
| Bender, DA | 1 |
| Bapurao, S | 1 |
| Krishnaswamy, K | 3 |
| Dickerson, JW | 1 |
| Wiryanti, J | 1 |
| Spivak, JL | 1 |
| Jackson, DL | 1 |
| Rao, SB | 1 |
| Raghuram, TC | 1 |
| Srikantia, SG | 1 |
| Schmutz, JL | 1 |
| Cuny, JF | 1 |
| Trechot, P | 1 |
| Weber, M | 1 |
| Beurey, J | 1 |
| Cook, NE | 1 |
| Carpenter, KJ | 1 |
| Serdaru, M | 1 |
| Hausser-Hauw, C | 1 |
| Laplane, D | 1 |
| Buge, A | 1 |
| Castaigne, P | 1 |
| Goulon, M | 1 |
| Lhermitte, F | 1 |
| Hauw, JJ | 1 |
| DiLorenzo, PA | 1 |
| Hankes, LV | 1 |
| Leklem, JE | 1 |
| Brown, RR | 1 |
| Mekel, RC | 1 |
| Hoffer, A | 1 |
| Binazzi, M | 1 |
| Calandra, P | 2 |
| György, P | 1 |
| Lambertz, J | 1 |
| Paupe, J | 1 |
| Bertaud, J | 1 |
| Vialatte, J | 1 |
1 review available for pyridoxine and Pellagra
| Article | Year |
|---|---|
Developments leading to the metabolic role of vitamin B 6.
Topics: Acrodynia; Adult; Aged; Aging; Amines; Animals; Arteriosclerosis; Aspartate Aminotransferases; Biolo | 1971 |
1 trial available for pyridoxine and Pellagra
| Article | Year |
|---|---|
Nicotinic acid in the treatment of schizophrenias. Practical and theoretical considerations.
Topics: Adrenochrome; Antipsychotic Agents; Ascorbic Acid; Clinical Trials as Topic; Drug Evaluation; Drug T | 1975 |
23 other studies available for pyridoxine and Pellagra
| Article | Year |
|---|---|
Pellagra: will we see it more frequently?
Topics: Antitubercular Agents; Female; Humans; Isoniazid; Middle Aged; Pellagra; Pyridoxine; Tuberculosis, P | 2009 |
Pyridoxine, an essential factor in the restoration of muscle power of Egyptian pellagrins.
Topics: Ethnicity; Humans; Pellagra; Pyridoxine; Vitamin B 6 | 1952 |
Oral lesions in niacin, riboflavin, pyridoxine, folic acid, and pantothenic acid deficiencies in adult dogs.
Topics: Folic Acid; Niacin; Pantothenic Acid; Pellagra; Pyridoxine; Riboflavin; Tongue; Vitamin B Deficiency | 1955 |
Complement-fixing murine typhus antibodies in vitamin deficiency states. II. Pyridoxine, and nicotinic acid deficiencies.
Topics: Animals; Antibodies; Antigens; Avitaminosis; Humans; Mice; Nicotinic Acids; Pellagra; Pyridoxine; Ty | 1951 |
Effects of vitamins B1, B2, B6 and C on erythrocyte enzymes in South African Bantu.
Topics: Alanine Transaminase; Ascorbic Acid; Black People; Carcinoma, Hepatocellular; Erythrocytes; Glutathi | 1982 |
[Dose-dependent pellagroid skin reaction caused by carbamazepine].
Topics: Anticonvulsants; Biopsy; Carbamazepine; Child; Diagnosis, Differential; Drug Eruptions; Epilepsy, To | 1998 |
Isoniazid induced pellagra despite pyridoxine supplementation.
Topics: Anti-Inflammatory Agents; Antitubercular Agents; Clobetasol; Drug Therapy, Combination; Humans; Ison | 1999 |
Isoniazid-induced pellagra despite vitamin-B6 supplementation.
Topics: Adult; Behcet Syndrome; Female; Humans; Isoniazid; Kynurenine; Mixed Function Oxygenases; Nicotinic | 1979 |
Vitamin B6 nutritional status of pellagrins and their leucine tolerance.
Topics: Adult; Drug Tolerance; Humans; Leucine; Middle Aged; NAD; Nutritional Requirements; Pellagra; Pyrido | 1978 |
Pellagra and mental disturbance.
Topics: Animals; Brain; Diet; Hartnup Disease; Humans; Mental Disorders; Nicotinic Acids; Pellagra; Pyridoxi | 1978 |
Pellagra: an analysis of 18 patients and a review of the literature.
Topics: Adult; Aged; Alcoholism; Brain Diseases; Dermatitis; Diarrhea; Female; Humans; Male; Middle Aged; Ne | 1977 |
Effect of vitamin B6 on leucine-induced changes in human subjects.
Topics: Adult; Blood Platelets; Drug Synergism; Edible Grain; Erythrocytes; Feeding Behavior; Humans; Hydrox | 1976 |
[Drug-induced pellagroid erythema. A case of pellagroid erythema caused by isoniazide].
Topics: Antineoplastic Agents; Erythema; Ethionamide; Female; Humans; Isoniazid; Middle Aged; Monoamine Oxid | 1987 |
Ethanol and leucine as possible stress factors in rats marginally deficient in niacin and vitamin B-6.
Topics: Analysis of Variance; Animals; Body Weight; Energy Intake; Ethanol; Leucine; Male; Niacin; Niacinami | 1988 |
The clinical spectrum of alcoholic pellagra encephalopathy. A retrospective analysis of 22 cases studied pathologically.
Topics: Adult; Aged; Alcoholism; Cognition Disorders; Confusion; Consciousness Disorders; Female; Humans; Ma | 1988 |
Pellagra-like syndrome associated with isoniazid therapy.
Topics: Adult; Facial Dermatoses; Female; Hand Dermatoses; Humans; Isoniazid; Nicotinic Acids; Pellagra; Pig | 1967 |
Tryptophan metabolism in patients with pellagra: problem of vitamin B 6 enzyme activity and feedback control of tryptophan pyrrolase enzyme.
Topics: Black or African American; Black People; Feedback; Female; Humans; Kynurenine; Male; Niacinamide; Ni | 1971 |
Treatment of hyperkinetic children with nicotinamide and pyridoxine.
Topics: Adolescent; Age Factors; Drug Synergism; Humans; Hyperkinesis; Male; Niacinamide; Pellagra; Pyridoxi | 1972 |
[Pellagra].
Topics: Female; Gastric Juice; Humans; Male; Middle Aged; Pellagra; Pyridoxine; Thiamine | 1973 |
Erythrocyte transaminase activity in human vitamin B 6 deficiency.
Topics: Adult; Aspartate Aminotransferases; Colorimetry; Deficiency Diseases; Erythrocytes; Humans; Metaboli | 1971 |
[New viewpoints on the pathogenesis of pellagra].
Topics: Humans; Kynurenine; Metabolic Diseases; Pellagra; Pyridoxine; Riboflavin; Tryptophan | 1970 |
[Pellagroid syndrome with pseudo-myopathic signs cured with pyridoxine].
Topics: Child, Preschool; Diagnosis, Differential; Female; Hartnup Disease; Humans; Infant; Lupus Erythemato | 1970 |
Vitamins of the B complex.
Topics: Aged; Alcoholism; Anemia, Hypochromic; Avitaminosis; Beriberi; Heart Failure; Humans; Isoniazid; Ner | 1968 |