Lymphoma, Primary Effusion

A rare neoplasm of large B-cells usually presenting as serious effusions without detectable tumor masses. The most common sites of involvement are the pleural, pericardial, and peritoneal cavities. It is associated with HUMAN HERPESVIRUS 8, most often occurring in the setting of immunodeficiency.

Synonym
Primary Effusion Lymphoma
Lymphoma, Primary Effusion

Excerpt	Reference
"Primary effusion lymphoma is a rare type of lymphoma which is confined to those body cavities associated with human herpes virus 8 infection in its development."	( Morohashi, K; Ohara, T; Okajima, M; Shimizu, N; Shimizu, T; Toyama, J, 2011)
"Primary effusion lymphoma is a rare non-Hodgkin lymphoma that presents with pleural effusions and lacking of tumour mass."	( Benito, A; Blanchard, MJ; Garcia-Vela, JA; López, S; Marquet, J; Velazquez-Kennedy, K, 2018)

Excerpt	Reference
"However, its role in primary effusion lymphoma has not been fully explored."	( Ahmed, M; Ahmed, SO; Al Abdulmohsen, S; Al-Kuraya, KS; Hussain, AR; Khan, OS; Platanias, LC; Uddin, S, 2012)

Excerpt	Reference
"In a mouse xenograft model of primary effusion lymphoma by BCBL-1 cells, triptolide treatment significantly inhibited ascites formation and diffused organ infiltration."	( Guo, W; Long, C; Sun, X; Wang, H; Wang, J; Zhou, H, 2016)

Timeframe	Studies, This Condition (%)	All Conditions %
pre-1990	0 (0.00)	23.3326
1990's	0 (0.00)	12.5806
2000's	11 (7.80)	18.1394
2010's	107 (75.89)	28.8240
2020's	23 (16.31)	9.53

Drug	Relationship Strength	Studies
alpha-hydroxyglutarate	low	1
phosphoserine	low	1
adenine	low	1
cytosine	low	2
niacinamide	low	1
phosphorylcholine	low	1
purine	low	1
berberine	low	1
chloroquine	low	1
miltefosine	low	1
entinostat	low	1
nimesulide	low	1
sobuzoxane	low	1
vorinostat	low	1
sulforaphane	low	1
thalidomide	low	3
prednisolone	low	4
prednisone	low	12
alanine	low	1
serine	low	1
tyrosine	low	1
cytarabine	low	2
4-butyrolactone	low	1
thiophenes	low	1
framycetin	low	1
ditiocarb	low	1
catechin	low	2
benzoxazoles	low	1
adamantane	low	3
thiazoles	low	1
pyrazines	low	6
cepharanthine	low	1
thymoquinone	low	1
acetylcysteine	low	1
nsc 65346	low	2
diallyl trisulfide	low	1
fluorescein-5-isothiocyanate	low	1
tiletamine hydrochloride	low	1
tetradecanoylphorbol acetate	low	1
nigericin	low	1
zidovudine	low	1
etoposide	low	4
lovastatin	low	1
cidofovir anhydrous	low	2
arctigenin	low	1
epigallocatechin gallate	low	2
triazoles	low	3
fluorodeoxyglucose f18	low	1
zoledronic acid	low	1
7-hydroxystaurosporine	low	1
narciclasine	low	1
neamine	low	1
rosiglitazone	low	1
lopinavir	low	1
artesunic acid	low	1
triptolide	low	2
deoxyglucose	low	1
fullerene c60	low	1
methotrexate	low	1
pomalidomide	low	4
perifosine	low	1
organophosphonates	low	2
lenalidomide	low	4
pifithrin mu	low	1
bortezomib	low	7
leupeptins	low	3
mannose-6-phosphate	low	1
lignans	low	1
betadex	low	1
tretinoin	low	1
resveratrol	low	1
tacrolimus	low	2
benzyloxycarbonylleucyl-leucyl-leucine aldehyde	low	3
bromochloroacetic acid	low	2
dimethyl fumarate	low	1
isomethyleugenol	low	1
stilbenes	low	1
polidocanol	low	1
capsaicin	low	2
dasatinib	low	4
naphthoquinones	low	1
sphingosine	low	2
quercetin	low	1
dinoprostone	low	1
apigenin	low	2
calcitriol	low	1
beta carotene	low	1
lipoxin a4	low	1
fucoxanthin	low	1
cucurbitacin b	low	1
garcinol	low	1
sphingosine 1-phosphate	low	2
sirolimus	low	4
n-(n-(3,5-difluorophenacetyl)alanyl)phenylglycine tert-butyl ester	low	1
ag-490	low	1
palbociclib	low	1
bay 11-7082	low	2
bay 11-7085	low	1
arsenic	low	1
geldanamycin	low	2
dimyristoylphosphatidylcholine	low	2
pepstatin	low	1
monorden	low	1
everolimus	low	1
tanespimycin	low	1
lactacystin	low	1
pep005	low	1
staurosporine	low	1
3-aminopyridine-2-carboxaldehyde thiosemicarbazone	low	1
acanthoic acid	low	1
adarotene	low	1
4-methylene-2-octyl-5-oxofuran-3-carboxylic acid	low	1
dehydroxymethylepoxyquinomicin	low	1
benzyloxycarbonyl-isoleucyl-glutamyl(o-tert-butyl)-alanyl-leucinal	low	1
hippuristanol	low	1
sepantronium	low	1
px 478	low	1
fucoxanthinol	low	1
nutlin-3a	low	3
crizotinib	low	1
dactolisib	low	2
cytochrome c-t	low	1
adenosine kinase	low	1
sodium salicylate	low	1
sphingosine kinase	low	1
tenovin-6	low	1
fit-039	low	1
piperidines	low	2
interleukin-8	low	1
5-(4-amino-1-propan-2-yl-3-pyrazolo[3,4-d]pyrimidinyl)-1,3-benzoxazol-2-amine	low	1
gsk1210151a	low	1
dolutegravir	low	1
transforming growth factor beta	low	1
3-(4-chlorophenyl)-adamantane-1-carboxylic acid (pyridin-4-ylmethyl)amide	low	2
cyclin d1	low	1
benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone	low	1
cyclosporine	low	1
angiogenin	low	2
ganciclovir	low	3
valganciclovir	low	2
phenanthrenes	low	2

Protein Targets (1,856)

Protein	Potency Measurements	Inhibition Measurements	Activation Measurements	Drugs
Ribonucleoside-diphosphate reductase subunit M2	0	1	0	1
CDGSH iron-sulfur domain-containing protein 1	0	4	0	4
RAR-related orphan receptor gamma	23	0	0	23
nuclear receptor subfamily 1, group I, member 3	24	0	0	24
retinoid X nuclear receptor alpha	21	0	0	21
estrogen-related nuclear receptor alpha	33	0	0	33
pregnane X nuclear receptor	20	0	0	20
peroxisome proliferator-activated receptor delta	14	0	0	14
Fatty acid synthase	0	3	0	3
Fatty acid synthase	0	1	0	1
Fatty acid synthase	0	2	0	2
Fumarate hydratase	16	0	0	16
PPM1D protein	18	0	0	18
EWS/FLI fusion protein	27	0	0	27
G	11	0	0	11
polyprotein	16	0	0	16
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform	0	4	4	8
Interferon beta	26	0	0	26
HLA class I histocompatibility antigen, B alpha chain	11	0	0	11
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	0	5	4	9
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform	0	3	4	7
Serine/threonine-protein kinase mTOR	0	9	5	14
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	0	4	4	8
Rapamycin-insensitive companion of mTOR	0	1	0	1
Regulatory-associated protein of mTOR	0	4	0	4
Phosphatidylinositol 3-kinase catalytic subunit type 3	0	1	1	2
Inositol hexakisphosphate kinase 1	11	0	0	11
Target of rapamycin complex 2 subunit MAPKAP1	0	1	0	1
Target of rapamycin complex subunit LST8	0	4	0	4
cytochrome P450 2C9, partial	11	0	0	11
Serine/threonine-protein kinase Chk1	0	2	7	9
3-phosphoinositide-dependent protein kinase 1	0	1	2	3
Cyclin-dependent kinase 1	0	8	7	15
Cyclin-dependent kinase 4	0	4	7	11
Cyclin-A2	0	3	0	3
G1/S-specific cyclin-D1	0	4	0	4
Cyclin-dependent kinase 2	0	5	8	13
Oxysterols receptor LXR-beta	0	0	1	2
Oxysterols receptor LXR-alpha	0	0	1	2
Chain A, JmjC domain-containing histone demethylation protein 3A	3	0	0	3
Chain A, 2-oxoglutarate Oxygenase	16	0	0	16
Chain A, ATP-DEPENDENT DNA HELICASE Q1	8	0	0	8
acetylcholinesterase	5	0	0	5
dopamine D1 receptor	2	0	0	2
15-lipoxygenase, partial	7	0	0	7
pregnane X receptor	4	0	0	4
phosphopantetheinyl transferase	20	0	0	20
USP1 protein, partial	18	0	0	18
NFKB1 protein, partial	6	0	0	6
Microtubule-associated protein tau	21	0	0	21
Thrombopoietin	4	0	0	4
AR protein	32	0	0	32
regulator of G-protein signaling 4	11	0	0	11
glucocorticoid receptor [Homo sapiens]	24	0	0	24
retinoic acid nuclear receptor alpha variant 1	24	0	0	24
farnesoid X nuclear receptor	18	0	0	18
estrogen nuclear receptor alpha	37	0	0	37
vitamin D (1,25- dihydroxyvitamin D3) receptor	14	0	0	14
arylsulfatase A	11	0	0	11
euchromatic histone-lysine N-methyltransferase 2	24	0	0	24
Bloom syndrome protein isoform 1	12	0	0	12
D(1A) dopamine receptor	4	0	0	4
thyroid hormone receptor beta isoform a	10	0	0	10
thyroid hormone receptor beta isoform 2	26	0	0	26
heat shock protein beta-1	12	0	0	12
flap endonuclease 1	9	0	0	9
geminin	34	0	0	34
peripheral myelin protein 22	18	0	0	18
survival motor neuron protein isoform d	16	0	0	16
muscarinic acetylcholine receptor M1	5	0	0	5
Histone deacetylase 3	0	7	2	12
Solute carrier family 22 member 6	0	1	0	3
Histone deacetylase 4	0	5	2	10
Guanine nucleotide-binding protein G	1	0	0	1
Histone deacetylase 1	0	9	4	16
Histone deacetylase 7	0	5	3	11
Histone deacetylase 2	0	8	4	15
Polyamine deacetylase HDAC10	0	5	2	10
Histone deacetylase 11	0	5	2	10
Ataxin-2	21	0	0	21
Histone deacetylase 8	0	6	3	12
Histone deacetylase 6	0	8	3	14
Histone deacetylase 9	0	5	2	10
Histone deacetylase 5	0	5	2	10
ATP-dependent phosphofructokinase	16	0	0	16
Retinoic acid receptor beta	0	2	3	8
Pup--protein ligase	0	1	0	1
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE	20	0	0	20
Chain A, MTA/SAH nucleosidase	0	1	0	1
Chain A, Ribosome-inactivating protein alpha-trichosanthin	0	0	1	1
Chain A, Ricin A chain	0	0	1	1
Chain A, Ribosome-inactivating protein 3	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
TDP1 protein	39	0	0	39
cytochrome P450 family 3 subfamily A polypeptide 4	20	0	0	20
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a	18	0	0	18
nuclear factor erythroid 2-related factor 2 isoform 2	13	0	0	13
importin subunit beta-1 isoform 1	3	0	0	3
snurportin-1	3	0	0	3
tumor susceptibility gene 101 protein	1	0	0	1
GTP-binding nuclear protein Ran isoform 1	2	0	0	2
lamin isoform A-delta10	20	0	0	20
Voltage-dependent calcium channel gamma-2 subunit	18	0	0	18
Bile salt export pump	0	32	0	32
Heat shock protein HSP 90-beta	0	6	4	13
Glutamate receptor 2	18	0	0	18
Xanthine dehydrogenase/oxidase	0	6	0	6
TAR DNA-binding protein 43	3	0	0	3
Protein mono-ADP-ribosyltransferase PARP15	0	2	0	2
Leucine-rich repeat serine/threonine-protein kinase 2	0	2	2	4
ATPase family AAA domain-containing protein 5	15	0	0	15
Chain A, TYROSYL-DNA PHOSPHODIESTERASE	15	0	0	15
Chain A, HADH2 protein	10	0	0	10
Chain B, HADH2 protein	10	0	0	10
Chain A, Ferritin light chain	9	0	0	9
Luciferase	11	0	0	11
endonuclease IV	5	0	0	5
thioredoxin reductase	14	0	0	14
WRN	1	0	0	1
chaperonin-containing TCP-1 beta subunit homolog	1	0	0	1
GLS protein	12	0	0	12
apical membrane antigen 1, AMA1	5	0	0	5
aldehyde dehydrogenase 1 family, member A1	21	0	0	21
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	10	0	0	10
nonstructural protein 1	4	0	0	4
NPYLR7B	0	0	1	1
glucocerebrosidase	6	0	0	6
bromodomain adjacent to zinc finger domain 2B	3	0	0	3
IDH1	8	0	0	8
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)	9	0	0	9
peripheral myelin protein 22 isoform 1	7	0	0	7
cellular tumor antigen p53 isoform a	5	0	0	5
polyunsaturated fatty acid lipoxygenase ALOX12	3	0	0	3
cytochrome P450 2C19 precursor	4	0	0	4
cytochrome P450 2C9 precursor	6	0	0	6
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1	11	0	0	11
vitamin D3 receptor isoform VDRA	17	0	0	17
chromobox protein homolog 1	13	0	0	13
parathyroid hormone/parathyroid hormone-related peptide receptor precursor	5	0	0	5
potassium voltage-gated channel subfamily H member 2 isoform d	10	0	0	10
mitogen-activated protein kinase 1	9	0	0	9
ras-related protein Rab-9A	6	0	0	6
serine/threonine-protein kinase mTOR isoform 1	8	0	0	8
histone-lysine N-methyltransferase 2A isoform 2 precursor	2	0	0	2
peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	6	0	0	6
DNA polymerase eta isoform 1	6	0	0	6
DNA polymerase iota isoform a (long)	14	0	0	14
urokinase-type plasminogen activator precursor	7	0	0	7
plasminogen precursor	7	0	0	7
urokinase plasminogen activator surface receptor precursor	7	0	0	7
DNA polymerase kappa isoform 1	10	0	0	10
cytochrome P450 3A4 isoform 1	14	0	0	14
M-phase phosphoprotein 8	9	0	0	9
lethal factor (plasmid)	2	0	0	2
pyruvate kinase PKM isoform b	2	0	0	2
Gamma-aminobutyric acid receptor subunit pi	14	1	1	16
Polyunsaturated fatty acid lipoxygenase ALOX15B	3	1	0	4
Tyrosine-protein kinase JAK2	0	3	3	6
Epidermal growth factor receptor	0	6	7	13
Receptor tyrosine-protein kinase erbB-2	0	4	2	6
Ornithine decarboxylase	2	0	0	3
Gamma-aminobutyric acid receptor subunit beta-1	14	1	1	16
Gamma-aminobutyric acid receptor subunit delta	14	1	1	16
Gamma-aminobutyric acid receptor subunit gamma-2	14	1	1	16
Gamma-aminobutyric acid receptor subunit alpha-5	14	1	1	16
Gamma-aminobutyric acid receptor subunit alpha-3	14	1	1	16
Tyrosine-protein kinase JAK1	0	2	7	9
Gamma-aminobutyric acid receptor subunit gamma-1	14	1	1	16
Gamma-aminobutyric acid receptor subunit alpha-2	14	1	1	16
Gamma-aminobutyric acid receptor subunit alpha-4	14	1	1	16
Gamma-aminobutyric acid receptor subunit gamma-3	14	1	1	16
Gamma-aminobutyric acid receptor subunit alpha-6	14	1	1	16
Glutamate receptor ionotropic, NMDA 1	0	2	1	5
Histamine H2 receptor	7	1	0	8
Tyrosine-protein kinase JAK3	0	4	2	6
Gamma-aminobutyric acid receptor subunit alpha-1	14	1	1	16
Gamma-aminobutyric acid receptor subunit beta-3	14	1	1	16
Gamma-aminobutyric acid receptor subunit beta-2	14	1	1	16
Glutamate receptor ionotropic, NMDA 2A	0	1	0	3
Glutamate receptor ionotropic, NMDA 2B	0	2	0	4
Glutamate receptor ionotropic, NMDA 2C	0	1	0	3
GABA theta subunit	14	1	1	16
Gamma-aminobutyric acid receptor subunit epsilon	14	1	1	16
Tyrosyl-DNA phosphodiesterase 1	0	2	0	2
large T antigen	0	2	0	2
Carbonic anhydrase 1	0	7	0	9
Carbonic anhydrase 2	0	8	1	11
Alanine racemase, biosynthetic	0	0	0	1
5-hydroxytryptamine receptor 1D	0	0	0	1
Proton-coupled amino acid transporter 1	0	2	0	2
Adenosine deaminase	0	0	0	1
Carbonic anhydrase 4	0	0	0	1
Methylcytosine dioxygenase TET2	0	1	1	2
Chain A, Putative fructose-1,6-bisphosphate aldolase	7	0	0	7
Chain A, (3R)-hydroxymyristoyl-acyl carrier protein dehydratase	0	2	0	2
Chain B, (3R)-hydroxymyristoyl-acyl carrier protein dehydratase	0	2	0	2
Chain A, (3R)-hydroxymyristoyl-acyl carrier protein dehydratase	0	2	0	2
Chain B, (3R)-hydroxymyristoyl-acyl carrier protein dehydratase	0	2	0	2
Chain A, (3R)-hydroxymyristoyl-acyl carrier protein dehydratase	0	2	0	2
Chain B, (3R)-hydroxymyristoyl-acyl carrier protein dehydratase	0	2	0	2
Chain A, Cruzipain	10	0	0	10
Chain A, Transthyretin	0	0	1	1
Chain A, Transthyretin	0	0	1	1
Chain A, Transthyretin	0	0	1	1
Chain A, Transthyretin	0	0	1	1
Chain B, Transthyretin	0	0	1	1
Chain A, Transthyretin	0	0	1	1
Chain B, Transthyretin	0	0	1	1
Chain A, Casein kinase II subunit alpha	0	1	0	1
Chain A, Casein kinase II subunit alpha	0	1	0	1
Chain A, Casein Kinase Ii Subunit Alpha	0	1	0	1
interleukin 8	1	0	0	1
BRCA1	2	0	0	2
RGS12	1	0	0	1
hypoxia-inducible factor 1 alpha subunit	9	0	0	9
ATAD5 protein, partial	10	0	0	10
GLI family zinc finger 3	21	0	0	21
Smad3	11	0	0	11
thyroid stimulating hormone receptor	7	0	0	7
estrogen receptor 2 (ER beta)	15	0	0	15
progesterone receptor	16	0	0	16
cytochrome P450 2D6	12	0	0	12
Neuraminidase	0	4	0	4
67.9K protein	13	0	0	13
Parkin	8	0	0	8
peroxisome proliferator activated receptor gamma	19	0	0	19
pyruvate kinase	2	0	0	2
aryl hydrocarbon receptor	8	0	0	8
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a	8	0	0	8
v-jun sarcoma virus 17 oncogene homolog (avian)	11	0	0	11
Histone H2A.x	11	0	0	11
Replicase polyprotein 1ab	0	5	4	9
cytochrome P450 2D6 isoform 1	3	0	0	3
NPC intracellular cholesterol transporter 1 precursor	7	0	0	7
hemoglobin subunit beta	1	0	0	1
histone deacetylase 9 isoform 3	5	0	0	5
guanine nucleotide-binding protein G(i) subunit alpha-1 isoform 1	1	0	0	1
glycogen synthase kinase-3 beta isoform 1	0	0	1	1
ubiquitin carboxyl-terminal hydrolase 2 isoform a	2	0	0	2
nuclear factor erythroid 2-related factor 2 isoform 1	21	0	0	21
nuclear receptor ROR-gamma isoform 1	20	0	0	20
neuropeptide S receptor isoform A	4	0	0	4
Gamma-aminobutyric acid receptor subunit pi	0	1	0	1
Gamma-aminobutyric acid receptor subunit delta	0	1	0	1
Polyphenol oxidase 2	0	3	0	5
Aldo-keto reductase family 1 member B10	0	2	0	2
G2/mitotic-specific cyclin-B2	0	2	0	2
Poly [ADP-ribose] polymerase tankyrase-1	0	1	0	1
Lysozyme C-1	0	1	0	1
Cationic trypsin	0	2	0	2
Transthyretin	0	0	4	4
Estrogen receptor	0	4	0	4
Glucocorticoid receptor	0	4	2	12
Cellular tumor antigen p53	29	2	0	31
Cytochrome P450 1A1	0	5	1	6
Amyloid-beta precursor protein	2	7	1	10
Integrin beta-3	4	0	0	4
Myeloperoxidase	0	3	0	3
Cytochrome P450 1A2	0	9	1	11
Beta-glucuronidase	0	1	0	1
Aldo-keto reductase family 1 member B1	0	7	0	7
Seed linoleate 13S-lipoxygenase-1	0	2	0	6
ATP-dependent translocase ABCB1	0	9	2	13
Neutrophil elastase	0	7	0	7
Integrin alpha-IIb	4	0	0	4
Poly [ADP-ribose] polymerase 1	0	2	0	2
Replicase polyprotein 1a	0	2	4	6
Replicase polyprotein 1ab	0	2	4	6
Replicase polyprotein 1ab	0	8	4	12
Replicase polyprotein 1ab	0	12	4	16
Androgen receptor	0	6	0	7
Sialidase	0	2	0	2
Serine/threonine-protein kinase pim-1	0	2	8	11
Aromatase	0	6	0	6
Angiotensin-converting enzyme	0	2	0	2
Cystic fibrosis transmembrane conductance regulator	0	1	2	3
17-beta-hydroxysteroid dehydrogenase type 1	0	1	0	1
Pyruvate kinase PKM	0	1	1	2
G2/mitotic-specific cyclin-B1	0	5	0	5
Gamma-aminobutyric acid receptor subunit alpha-1	0	1	0	1
Urease subunit alpha	0	3	0	3
Aldo-keto reductase family 1 member B1	0	2	0	2
G2/mitotic-specific cyclin-B	0	2	0	2
Mucin-1	0	1	0	1
Glycogen synthase kinase-3 beta	0	2	0	2
Gamma-aminobutyric acid receptor subunit beta-1	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-2	0	1	0	1
Casein kinase II subunit alpha'	0	3	7	10
Amine oxidase [flavin-containing] A	0	5	0	5
Acetylcholinesterase	0	5	0	5
Carbonic anhydrase 4	0	5	0	6
Amine oxidase [flavin-containing] B	0	6	0	6
Dipeptidyl peptidase 4	0	4	0	4
Proteasome subunit beta type-5	0	10	0	11
Gamma-aminobutyric acid receptor subunit beta-3	0	1	0	1
Substance-P receptor	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-5	0	1	0	1
Multidrug resistance-associated protein 1	0	2	0	3
Gamma-aminobutyric acid receptor subunit alpha-3	0	1	0	1
Prostaglandin G/H synthase 2	0	10	2	12
Mu-type opioid receptor	0	0	0	2
Receptor-type tyrosine-protein kinase FLT3	0	6	7	13
Testosterone 17-beta-dehydrogenase 3	0	1	0	1
17-beta-hydroxysteroid dehydrogenase type 2	0	2	0	2
Acetylcholinesterase	0	1	0	1
Peroxisome proliferator-activated receptor gamma	0	0	2	2
Delta-type opioid receptor	0	1	0	3
Kappa-type opioid receptor	0	0	0	2
Homeobox protein Nkx-2.5	0	1	0	1
Tyrosine-protein kinase SYK	0	3	9	12
Gamma-aminobutyric acid receptor subunit alpha-2	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-2	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-4	0	1	0	1
Glycogen synthase kinase-3 alpha	0	2	7	9
Glycogen synthase kinase-3 beta	0	2	7	9
Estrogen receptor	0	0	1	1
Nuclear receptor ROR-gamma	6	1	1	8
Death-associated protein kinase 1	0	4	2	6
Mitogen-activated protein kinase 10	0	2	6	8
Beta-secretase 1	0	6	0	7
Casein kinase II subunit beta	0	3	0	3
Casein kinase II subunit alpha	0	4	2	6
Urease subunit beta	0	3	0	3
Gamma-aminobutyric acid receptor subunit epsilon	0	1	0	1
Disintegrin and metalloproteinase domain-containing protein 17	2	1	0	3
Lactoperoxidase	0	2	0	3
Xanthine dehydrogenase/oxidase	0	3	0	4
MO15-related protein kinase Pfmrk	0	2	0	2
Inositol monophosphatase 1	5	0	0	5
Cyclin-dependent kinase 6	0	4	7	11
Cyclin-dependent-like kinase 5	0	3	7	10
Cyclin homolog	0	2	0	2
Transcription factor GATA-4	0	1	0	1
Cyclin-dependent kinase 5 activator 1	0	3	0	3
Gamma-aminobutyric acid receptor subunit alpha-6	0	1	0	1
Mitogen-activated protein kinase 14	0	6	8	14
Cytochrome P450 1B1	0	8	1	9
Carbonic anhydrase 3	0	3	0	3
Substance-K receptor	0	2	0	2
Reverse transcriptase/RNaseH	0	4	2	9
Integrase	0	4	1	5
Gamma-aminobutyric acid receptor subunit gamma-1	0	1	0	1
Casein kinase II subunit alpha 3	0	3	0	3
Inositol polyphosphate multikinase	0	2	0	2
G2/mitotic-specific cyclin-B3	0	2	0	2
Estrogen receptor beta	0	3	0	3
Enoyl-acyl-carrier protein reductase	0	5	0	5
Aurora kinase B	0	4	7	11
NACHT, LRR and PYD domains-containing protein 3	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-3	0	1	0	1
Myocilin	0	0	1	1
Cyclin-dependent kinase 1	0	2	0	2
Prenyltransferase homolog	0	0	0	2
Poly [ADP-ribose] polymerase tankyrase-2	0	1	0	1
MAP kinase-interacting serine/threonine-protein kinase 2	0	1	2	3
Carboxylic ester hydrolase	0	1	0	1
NADPH oxidase 4	0	2	0	2
Dipeptidyl peptidase 3	0	2	0	2
Estrogen receptor beta	0	0	1	1
Inositol hexakisphosphate kinase 2	0	2	0	2
Short transient receptor potential channel 5	0	2	0	2
Gamma-aminobutyric acid receptor subunit theta	0	1	0	1
Broad substrate specificity ATP-binding cassette transporter ABCG2	0	7	1	9
Sialidase-2	0	2	0	2
2,3-bisphosphoglycerate-independent phosphoglycerate mutase	1	0	0	1
Dual specificity mitogen-activated protein kinase kinase 1	0	3	7	10
hypothetical protein, conserved	2	0	0	2
atrial natriuretic peptide receptor 2 precursor	4	0	0	4
histone acetyltransferase KAT2A isoform 1	10	0	0	10
Nuclear factor NF-kappa-B p105 subunit	0	4	0	4
Alpha-synuclein	3	2	0	5
Nuclear factor NF-kappa-B p100 subunit	0	4	0	4
Transcription factor p65	0	4	0	4
NACHT, LRR and PYD domains-containing protein 3	0	2	0	2
Class A sortase SrtA	0	1	0	1
Nrf2	4	0	0	4
atrial natriuretic peptide receptor 1 precursor	2	0	0	2
transient receptor potential cation channel subfamily V member 1	2	0	0	2
D(1A) dopamine receptor	0	2	0	2
D(3) dopamine receptor	0	2	0	2
C-C chemokine receptor type 2	0	3	0	3
Proteasome subunit beta type-1	0	5	0	6
Proteasome subunit beta type-2	0	5	0	6
Proteasome subunit beta type-11	0	3	0	3
Calpain-9	0	1	0	1
Proteasome subunit alpha type-7	0	3	0	3
Cathepsin B	0	3	0	3
Indoleamine 2,3-dioxygenase 1	0	1	0	1
Calpain-2 catalytic subunit	0	1	0	1
Proteasome subunit alpha type-1	0	3	0	3
Proteasome subunit alpha type-2	0	3	0	3
Proteasome subunit alpha type-3	0	3	0	3
Proteasome subunit alpha type-4	0	3	0	3
NF-kappa-B inhibitor alpha	0	0	1	1
Proteasome subunit beta type-8	0	3	0	3
Proteasome subunit beta type-9	0	3	0	3
Proteasome subunit alpha type-5	0	3	0	3
Proteasome subunit beta type-4	0	3	0	3
Proteasome subunit beta type-6	0	3	0	3
Proteasome subunit beta type-10	0	3	0	3
Cathepsin K	0	1	0	1
Proteasome subunit beta type-3	0	3	0	3
Proteasome subunit alpha type-6	0	3	0	3
Proteasome subunit alpha-type 8	0	3	0	3
Proteasome subunit beta type-7	0	3	0	3
Gamma-secretase subunit PEN-2	0	2	0	2
Telomerase reverse transcriptase	0	2	0	2
Acetylcholinesterase	0	3	0	3
Lysine-specific histone demethylase 1A	0	5	0	5
Neuraminidase	0	2	0	2
Neuraminidase	0	1	0	1
Cholinesterase	0	2	0	2
Tyrosine-protein phosphatase non-receptor type 1	0	4	0	4
Aldo-keto reductase family 1 member C3	0	1	0	1
Prolyl endopeptidase	0	2	0	2
Aldo-keto reductase family 1 member C2	0	1	0	1
Cholinesterase	0	3	0	3
Potassium voltage-gated channel subfamily H member 2	0	10	0	10
core protein, partial	0	1	0	1
Solute carrier organic anion transporter family member 1B3	0	5	0	6
Solute carrier organic anion transporter family member 1B1	0	6	0	6
Chain A, D-MALTODEXTRIN BINDING PROTEIN	0	0	1	1
Chain A, Limit Dextrinase	0	0	1	1
Chain A, Solute-binding protein	0	0	1	1
Chain A, Solute-binding protein	0	0	1	1
Chain B, SusD	0	0	1	1
Chain A, SusD	0	0	1	1
Chain A, SusD	0	0	1	1
Chain A, Alpha-hemolysin	0	0	1	1
Chain B, Alpha-hemolysin	0	0	1	1
Chain C, Alpha-hemolysin	0	0	1	1
Chain D, Alpha-hemolysin	0	0	1	1
Chain E, Alpha-hemolysin	0	0	1	1
Chain F, Alpha-hemolysin	0	0	1	1
Chain G, Alpha-hemolysin	0	0	1	1
activating transcription factor 6	11	0	0	11
Chain H, Proteasome component PUP1	0	1	0	1
Chain I, Proteasome component PUP3	0	1	0	1
Chain K, Proteasome component PRE2	0	1	0	1
Chain L, Proteasome component C5	0	1	0	1
Chain K, Proteasome component PRE2	0	1	0	1
Chain L, Proteasome component C5	0	1	0	1
caspase 7, apoptosis-related cysteine protease	9	0	0	9
caspase-3	9	0	0	9
nuclear receptor subfamily 1, group I, member 2	8	0	0	8
Caspase-7	5	0	0	5
caspase-3	5	0	0	5
26S proteasome non-ATPase regulatory subunit 11	0	1	0	1
26S proteasome non-ATPase regulatory subunit 12	0	1	0	1
26S proteasome non-ATPase regulatory subunit 14	0	1	0	1
ATP-binding cassette sub-family C member 3	0	23	0	23
Multidrug resistance-associated protein 4	0	23	0	25
26S proteasome non-ATPase regulatory subunit 3	0	1	0	1
Carbonic anhydrase 12	0	4	0	5
Prothrombin	0	3	2	6
Chymotrypsinogen A	0	2	0	2
Carbonic anhydrase 3	0	3	0	4
Cathepsin G	0	2	0	2
Lysosomal protective protein	0	1	0	1
Chymotrypsinogen B	0	2	0	2
26S proteasome regulatory subunit 6A	0	1	0	1
Carbonic anhydrase 6	0	4	0	5
Chymase	0	1	0	1
Proteasome subunit beta type-8	0	1	0	1
Carbonic anhydrase 5A, mitochondrial	0	3	0	4
26S proteasome regulatory subunit 7	0	1	0	1
Lon protease homolog, mitochondrial	0	1	0	1
Carbonic anhydrase 7	0	3	0	4
26S proteasome regulatory subunit 6B	0	1	7	8
26S proteasome non-ATPase regulatory subunit 8	0	1	0	1
26S proteasome non-ATPase regulatory subunit 7	0	1	0	1
26S proteasome non-ATPase regulatory subunit 4	0	1	0	1
26S proteasome complex subunit SEM1	0	1	0	1
26S proteasome regulatory subunit 4	0	1	0	1
26S proteasome regulatory subunit 8	0	1	0	1
26S proteasome regulatory subunit 10B	0	1	0	1
Beta-carbonic anhydrase 1	0	1	0	1
26S proteasome non-ATPase regulatory subunit 2	0	1	0	1
26S proteasome non-ATPase regulatory subunit 6	0	1	0	1
Proteasomal ubiquitin receptor ADRM1	0	1	0	1
Carbonic anhydrase 9	0	4	0	5
ATP-dependent Clp protease proteolytic subunit	0	1	1	2
Carbonic anhydrase 13	0	2	0	2
Canalicular multispecific organic anion transporter 1	0	24	0	25
26S proteasome non-ATPase regulatory subunit 1	0	1	0	1
Carbonic anhydrase 15	0	2	0	3
Carbonic anhydrase 14	0	4	0	5
26S proteasome non-ATPase regulatory subunit 13	0	1	0	1
Carbonic anhydrase 5B, mitochondrial	0	3	0	4
thyroid stimulating hormone receptor	10	0	0	10
Chain A, Vitamin D Nuclear Receptor	0	0	1	1
Chain A, Beta-lactamase	8	0	0	8
Vitamin D3 receptor	0	0	1	1
thioredoxin glutathione reductase	7	0	0	7
Vitamin D-binding protein	0	0	1	1
Cytochrome P450 3A4	0	18	3	23
Cytochrome P450 2D6	0	8	1	9
Vitamin D3 receptor	0	1	2	4
Cytochrome P450 2C9	0	11	2	14
Vitamin D3 receptor	0	1	1	3
Retinoic acid receptor RXR-alpha	0	2	3	5
Cytochrome P450 2C19	0	11	1	12
Kappa-type opioid receptor	0	1	1	2
Vitamin D3 receptor	0	0	1	1
1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial	0	0	1	1
Vitamin D3 receptor	0	1	1	2
Transporter	0	1	0	1
Vitamin D3 receptor A	0	0	2	2
Transient receptor potential cation channel subfamily V member 1	0	3	1	4
NADH-ubiquinone oxidoreductase chain 1	0	1	0	1
Polyunsaturated fatty acid 5-lipoxygenase	0	4	0	5
Cannabinoid receptor 1	0	2	0	2
Prostaglandin G/H synthase 1	0	4	0	4
Cannabinoid receptor 2	0	2	0	2
Spike glycoprotein	15	1	4	20
D(2) dopamine receptor	0	0	1	1
Potassium voltage-gated channel subfamily A member 1	0	1	0	1
Corticotropin-releasing factor receptor 2	0	1	0	1
Transient receptor potential cation channel subfamily V member 1	0	2	1	4
Transient receptor potential cation channel subfamily V member 4	0	0	1	1
Transient receptor potential cation channel subfamily V member 2	0	0	1	1
DNA polymerase beta	6	0	0	6
Prostaglandin G/H synthase 1	0	1	0	1
Arginase	0	3	0	3
Pancreatic triacylglycerol lipase	0	2	0	2
Prostaglandin G/H synthase 1	0	3	2	5
Sucrase-isomaltase, intestinal	0	2	0	2
Adenosine receptor A1	1	3	0	5
Adenosine receptor A2a	0	3	0	4
Melatonin receptor type 1A	0	0	1	1
Melatonin receptor type 1B	0	0	1	1
Prostaglandin G/H synthase 2	0	4	0	4
Dihydroorotate dehydrogenase	0	1	0	1
glp-1 receptor, partial	5	0	0	5
SMAD family member 2	9	0	0	9
SMAD family member 3	9	0	0	9
Trypanothione reductase	0	1	0	1
glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase	0	1	0	1
Spike glycoprotein	0	1	4	5
glucose-6-phosphate 1-dehydrogenase isoform b	0	1	0	1
Transmembrane protease serine 2	0	1	4	5
Dihydrofolate reductase	0	2	0	2
DNA ligase	0	1	0	1
Riboflavin-binding protein	0	0	1	1
Major prion protein	0	0	1	1
Histidine-rich protein PFHRP-II	0	1	0	2
Procathepsin L	0	3	4	7
Muscarinic acetylcholine receptor M2	0	1	0	1
Muscarinic acetylcholine receptor M4	0	1	0	1
Muscarinic acetylcholine receptor M5	0	1	0	1
Alpha-2A adrenergic receptor	0	1	0	1
Spike glycoprotein	0	1	0	1
Muscarinic acetylcholine receptor M1	0	1	0	1
Ribosyldihydronicotinamide dehydrogenase [quinone]	0	3	8	11
Alpha-2B adrenergic receptor	0	1	0	1
Alpha-2C adrenergic receptor	0	1	0	1
DNA ligase 1	0	1	0	1
Muscarinic acetylcholine receptor M3	0	1	0	1
Nuclear receptor subfamily 4 group A member 2	0	0	1	1
Calcium-dependent protein kinase 1	0	0	1	1
DNA ligase A	0	1	0	1
Sigma intracellular receptor 2	0	2	0	2
Phosphoethanolamine N-methyltransferase	0	1	0	1
Sigma non-opioid intracellular receptor 1	0	1	0	1
Angiotensin-converting enzyme 2	0	1	4	5
Cysteine proteinase falcipain 2a	0	1	0	1
Cysteine proteinase falcipain 2a	0	1	0	1
Thymidine kinase	0	2	0	2
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase	0	0	1	1
Thymidine kinase	0	0	0	1
Solute carrier family 22 member 6	0	1	0	6
Leukotriene C4 synthase	0	0	2	2
tyrosine-protein kinase Yes	6	0	0	6
Bone morphogenetic protein receptor type-1B	0	0	7	7
Membrane-associated progesterone receptor component 1	0	0	5	5
Cell division cycle 7-related protein kinase	0	0	4	4
Serine/threonine-protein kinase PLK4	0	0	7	7
Serine/threonine-protein kinase 25	0	0	2	2
ATP-dependent RNA helicase DDX3X	0	0	7	7
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta	0	1	2	3
Pyridoxal kinase	0	0	7	7
Citron Rho-interacting kinase	0	0	7	7
Serine/threonine-protein kinase RIO3	0	0	2	2
Dual specificity mitogen-activated protein kinase kinase 7	0	0	2	2
Inhibitor of nuclear factor kappa-B kinase subunit beta	0	1	2	3
Peripheral plasma membrane protein CASK	0	0	2	2
Aurora kinase A	0	1	7	8
Cyclin-G-associated kinase	0	0	7	7
Serine/threonine-protein kinase DCLK1	0	0	2	2
Inhibitor of nuclear factor kappa-B kinase subunit alpha	0	1	2	3
Muscle, skeletal receptor tyrosine-protein kinase	0	0	2	2
Ephrin type-B receptor 6	0	0	7	7
Peroxisomal acyl-coenzyme A oxidase 3	0	0	7	7
Mitogen-activated protein kinase 13	0	1	2	3
Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2	0	1	0	1
Mitogen-activated protein kinase kinase kinase 13	0	0	2	2
Death-associated protein kinase 3	0	0	2	2
Mitogen-activated protein kinase kinase kinase 7	0	0	2	2
Receptor-interacting serine/threonine-protein kinase 2	0	2	7	9
Mitotic checkpoint serine/threonine-protein kinase BUB1	0	0	6	6
NUAK family SNF1-like kinase 1	0	2	2	4
Dynamin-like 120 kDa protein, mitochondrial	0	0	7	7
Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma	0	0	2	2
Eukaryotic translation initiation factor 5B	0	0	6	6
Rho-associated protein kinase 2	0	0	7	7
Serine/threonine-protein kinase ULK1	0	0	7	7
Serine/threonine-protein kinase/endoribonuclease IRE1	0	0	7	7
Ribosomal protein S6 kinase alpha-5	0	0	7	7
U5 small nuclear ribonucleoprotein 200 kDa helicase	0	1	7	8
Ribosomal protein S6 kinase alpha-4	0	0	7	7
Serine/threonine-protein kinase 16	0	0	7	7
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma	0	0	2	2
Serine/threonine-protein kinase PAK 3	0	0	2	2
Cyclin-dependent kinase-like 5	0	0	4	4
Serine/threonine-protein kinase 17B	0	0	2	2
Serine/threonine-protein kinase 10	0	0	7	7
Serine/threonine-protein kinase D3	0	0	9	9
Cyclin-dependent kinase 14	0	0	2	2
Structural maintenance of chromosomes protein 2	0	0	7	7
Mitogen-activated protein kinase kinase kinase 6	0	0	7	7
Sodium-dependent phosphate transport protein 2B	0	1	0	1
Serine/threonine-protein kinase OSR1	0	0	2	2
Mitogen-activated protein kinase kinase kinase kinase 4	0	0	7	7
Serine/threonine-protein kinase LATS1	0	0	7	7
Serine/threonine-protein kinase PAK 4	0	0	7	7
Serine/threonine-protein kinase Chk2	0	0	2	2
Tyrosine-protein kinase ABL1	0	8	9	21
Tyrosine-protein kinase ABL1	0	2	0	2
RAF proto-oncogene serine/threonine-protein kinase	0	1	2	3
HLA class II histocompatibility antigen gamma chain	0	1	0	1
High affinity nerve growth factor receptor	0	1	6	7
Guanine nucleotide-binding protein G(i) subunit alpha-2	0	0	5	5
ADP/ATP translocase 2	0	0	7	7
Protein kinase C beta type	0	2	9	11
Insulin receptor	0	2	7	9
Tyrosine-protein kinase Lck	0	6	7	13
Tyrosine-protein kinase Fyn	0	4	7	11
Glycogen phosphorylase, liver form	0	1	7	8
Nucleophosmin	0	1	0	1
Tyrosine-protein kinase Fes/Fps	0	0	7	7
Macrophage colony-stimulating factor 1 receptor	0	4	2	6
Adenine phosphoribosyltransferase	0	0	6	6
Tyrosine-protein kinase Yes	0	2	7	9
Tyrosine-protein kinase Lyn	0	1	7	8
Proto-oncogene tyrosine-protein kinase receptor Ret	0	3	7	10
Insulin-like growth factor 1 receptor	0	3	7	10
Signal recognition particle receptor subunit alpha	0	0	7	7
Cytochrome c1, heme protein, mitochondrial	0	0	7	7
Hepatocyte growth factor receptor	0	5	6	11
Tyrosine-protein kinase HCK	0	2	7	9
Proto-oncogene tyrosine-protein kinase ROS	0	2	2	4
Platelet-derived growth factor receptor beta	0	4	7	11
Tyrosine-protein kinase Fgr	0	1	4	5
Wee1-like protein kinase 2	0	0	2	2
Uncharacterized serine/threonine-protein kinase SBK3	0	0	2	2
Serine/threonine-protein kinase A-Raf	0	0	7	7
Mast/stem cell growth factor receptor Kit	0	1	2	3
Glycogen phosphorylase, brain form	0	0	7	7
Breakpoint cluster region protein	0	4	8	16
Fibroblast growth factor receptor 1	0	3	7	10
DNA topoisomerase 2-alpha	0	1	6	12
ADP/ATP translocase 3	0	0	7	7
Inosine-5'-monophosphate dehydrogenase 2	0	0	6	6
Proto-oncogene tyrosine-protein kinase Src	0	5	7	12
cAMP-dependent protein kinase type II-alpha regulatory subunit	0	0	6	6
Insulin receptor-related protein	0	0	2	2
Serine/threonine-protein kinase B-raf	0	1	7	8
Phosphorylase b kinase gamma catalytic chain, liver/testis isoform	0	0	7	7
Platelet-derived growth factor receptor alpha	0	3	2	5
Tyrosine-protein kinase Fer	0	0	7	7
Protein kinase C alpha type	0	2	10	12
cAMP-dependent protein kinase catalytic subunit alpha	0	0	7	7
Vascular endothelial growth factor receptor 1	0	1	2	3
General transcription and DNA repair factor IIH helicase subunit XPD	0	0	7	7
Interferon-induced, double-stranded RNA-activated protein kinase	0	0	2	2
Ras-related protein Rab-6A	0	0	7	7
Serine/threonine-protein kinase MAK	0	0	2	2
Cyclin-dependent kinase 11B	0	0	2	2
Ephrin type-A receptor 1	0	0	6	6
Fibroblast growth factor receptor 2	0	0	2	2
Receptor tyrosine-protein kinase erbB-3	0	0	2	2
Multifunctional protein ADE2	0	0	7	7
Fibroblast growth factor receptor 4	0	0	2	2
Fibroblast growth factor receptor 3	0	1	2	3
cAMP-dependent protein kinase catalytic subunit gamma	0	0	6	6
cAMP-dependent protein kinase catalytic subunit beta	0	0	7	7
Ferrochelatase, mitochondrial	0	0	7	7
Ribosomal protein S6 kinase beta-1	0	1	5	6
Protein kinase C eta type	0	0	4	4
Beta-adrenergic receptor kinase 1	0	1	7	8
Probable ATP-dependent RNA helicase DDX6	0	0	7	7
Activin receptor type-2A	0	0	2	2
Mitogen-activated protein kinase 3	0	0	7	7
MAP/microtubule affinity-regulating kinase 3	0	0	7	7
Deoxycytidine kinase	0	0	7	8
Mitogen-activated protein kinase 1	0	1	7	8
Ephrin type-A receptor 2	0	2	7	9
Ephrin type-A receptor 3	0	0	2	2
Ephrin type-A receptor 8	0	0	2	2
Ephrin type-B receptor 2	0	2	7	9
Leukocyte tyrosine kinase receptor	0	0	2	2
Non-receptor tyrosine-protein kinase TYK2	0	1	7	8
UMP-CMP kinase	0	0	6	6
Phosphatidylethanolamine-binding protein 1	0	0	6	6
Wee1-like protein kinase	0	0	7	7
Heme oxygenase 2	0	0	7	7
Tyrosine-protein kinase receptor UFO	0	2	2	4
Mitogen-activated protein kinase 4	0	0	2	2
S-adenosylmethionine synthase isoform type-2	0	0	7	7
DnaJ homolog subfamily A member 1	0	0	7	7
RAC-alpha serine/threonine-protein kinase	0	4	7	11
RAC-beta serine/threonine-protein kinase	0	2	7	9
G protein-coupled receptor kinase 4	0	0	2	2
Dual specificity protein kinase TTK	0	0	5	5
DNA replication licensing factor MCM4	0	0	7	7
Myosin-10	0	0	6	6
Tyrosine-protein kinase receptor Tie-1	0	0	2	2
Vascular endothelial growth factor receptor 3	0	0	2	2
Vascular endothelial growth factor receptor 2	0	4	2	6
Dual specificity mitogen-activated protein kinase kinase 2	0	1	7	8
Bone morphogenetic protein receptor type-1A	0	0	7	7
Activin receptor type-1B	0	0	7	7
TGF-beta receptor type-1	0	0	7	7
Serine/threonine-protein kinase receptor R3	0	0	3	3
TGF-beta receptor type-2	0	0	6	6
Electron transfer flavoprotein subunit beta	0	0	6	6
Tyrosine-protein kinase CSK	0	1	7	8
Glycine--tRNA ligase	0	0	7	7
Protein kinase C iota type	0	0	9	9
Exosome RNA helicase MTR4	0	0	7	7
Megakaryocyte-associated tyrosine-protein kinase	0	0	2	2
Tyrosine-protein kinase Tec	0	1	7	8
Tyrosine-protein kinase TXK	0	1	2	3
Tyrosine-protein kinase ABL2	0	0	7	7
Tyrosine-protein kinase FRK	0	0	7	7
G protein-coupled receptor kinase 6	0	0	5	5
Tyrosine-protein kinase ZAP-70	0	0	2	2
Mitogen-activated protein kinase 8	0	0	7	7
Mitogen-activated protein kinase 9	0	0	7	7
Dual specificity mitogen-activated protein kinase kinase 4	0	0	3	3
Dual specificity mitogen-activated protein kinase kinase 3	0	0	7	7
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha	0	0	5	5
Casein kinase I isoform alpha	0	1	7	8
Casein kinase I isoform delta	0	0	7	7
MAP kinase-activated protein kinase 2	0	1	7	8
Cyclin-dependent kinase 8	0	0	2	2
Elongation factor Tu, mitochondrial	0	0	7	7
Choline-phosphate cytidylyltransferase A	0	0	7	7
Cysteine--tRNA ligase, cytoplasmic	0	0	6	6
Casein kinase I isoform epsilon	0	0	7	7
Very long-chain specific acyl-CoA dehydrogenase, mitochondrial	0	0	7	7
Dual specificity protein kinase CLK1	0	0	7	7
Dual specificity protein kinase CLK2	0	0	6	6
Dual specificity protein kinase CLK3	0	0	5	5
Cyclin-dependent kinase 7	0	3	7	10
Cyclin-dependent kinase 9	0	3	7	10
Ras-related protein Rab-27A	0	0	7	7
Tyrosine-protein kinase Blk	0	1	2	3
Interleukin-1 receptor-associated kinase 1	0	0	7	7
Ribosomal protein S6 kinase alpha-3	0	1	7	8
Cytoplasmic tyrosine-protein kinase BMX	0	1	2	3
cAMP-dependent protein kinase catalytic subunit PRKX	0	0	2	2
Serine/threonine-protein kinase Nek2	0	1	7	8
Serine/threonine-protein kinase Nek3	0	0	7	7
Serine/threonine-protein kinase Nek4	0	0	2	2
Dual specificity mitogen-activated protein kinase kinase 6	0	0	7	7
Serine/threonine-protein kinase PLK1	0	2	4	6
LIM domain kinase 1	0	1	7	8
LIM domain kinase 2	0	1	7	8
Mitogen-activated protein kinase 12	0	1	2	3
Tyrosine--tRNA ligase, cytoplasmic	0	0	7	7
5'-AMP-activated protein kinase subunit gamma-1	0	0	7	7
5'-AMP-activated protein kinase catalytic subunit alpha-2	0	0	2	2
Ephrin type-B receptor 3	0	0	7	7
Ephrin type-A receptor 5	0	0	7	7
Ephrin type-B receptor 4	0	2	7	9
Ephrin type-B receptor 1	0	0	2	2
Ephrin type-A receptor 4	0	0	7	7
Adenylate kinase 2, mitochondrial	0	0	7	7
Adenosine kinase	0	1	7	8
Hormonally up-regulated neu tumor-associated kinase	0	0	2	2
Serine/threonine-protein kinase SIK1	0	2	2	4
Receptor-interacting serine/threonine-protein kinase 4	0	0	2	2
Ras-related protein Rab-10	0	0	7	7
Cell division control protein 2 homolog	0	0	2	2
Actin-related protein 3	0	0	7	7
Actin-related protein 2	0	0	7	7
Calcium-dependent protein kinase 1	0	0	2	2
GTP-binding nuclear protein Ran	0	0	7	7
Phosphatidylinositol 5-phosphate 4-kinase type-2 beta	0	0	2	2
SRSF protein kinase 2	0	0	2	2
Casein kinase I isoform gamma-2	0	0	6	6
Mitogen-activated protein kinase kinase kinase 9	0	0	2	2
ALK tyrosine kinase receptor	0	1	0	1
Serine/threonine-protein kinase PknB	0	0	2	2
Cyclin-dependent kinase 3	0	0	6	6
Cyclin-dependent kinase-like 1	0	0	2	2
Cyclin-dependent kinase 16	0	0	7	7
Cyclin-dependent kinase 17	0	0	7	7
ATP-dependent 6-phosphofructokinase, platelet type	0	0	7	7
Protein kinase C epsilon type	0	2	4	6
Angiopoietin-1 receptor	0	1	2	3
Mitogen-activated protein kinase kinase kinase 10	0	0	2	2
Angiopoietin-1 receptor	0	1	0	1
DNA topoisomerase 2-beta	0	1	8	15
Protein kinase C theta type	0	0	9	9
Activin receptor type-1	0	0	7	7
Macrophage-stimulating protein receptor	0	1	7	8
Focal adhesion kinase 1	0	2	7	9
Protein kinase C delta type	0	2	9	11
Tyrosine-protein kinase BTK	0	3	7	10
Tyrosine-protein kinase receptor TYRO3	0	1	2	3
Cyclin-dependent kinase 18	0	0	4	4
Activated CDC42 kinase 1	0	1	7	8
Epithelial discoidin domain-containing receptor 1	0	3	7	10
Tyrosine-protein kinase ITK/TSK	0	1	2	3
Myotonin-protein kinase	0	0	2	2
Mitogen-activated protein kinase kinase kinase kinase 2	0	0	7	7
Mitogen-activated protein kinase kinase kinase 12	0	0	2	2
Tyrosine-protein kinase Mer	0	1	4	5
Serine/threonine-protein kinase 4	0	0	7	7
5'-AMP-activated protein kinase catalytic subunit alpha-1	0	0	7	7
Serine/threonine-protein kinase PAK 1	0	1	2	3
Dual specificity mitogen-activated protein kinase kinase 5	0	0	7	7
Mitogen-activated protein kinase 7	0	0	7	7
Serine/threonine-protein kinase PAK 2	0	0	6	6
Serine/threonine-protein kinase 3	0	0	7	7
Mitogen-activated protein kinase kinase kinase 1	0	0	7	7
cGMP-dependent protein kinase 2	0	0	2	2
Integrin-linked protein kinase	0	0	7	7
Rho-associated protein kinase 1	0	0	7	7
Non-receptor tyrosine-protein kinase TNK1	0	0	7	7
Serine/threonine-protein kinase PRP4 homolog	0	0	2	2
Receptor-interacting serine/threonine-protein kinase 1	0	0	2	2
Calcium/calmodulin-dependent protein kinase type II subunit beta	0	1	2	3
Calcium/calmodulin-dependent protein kinase type II subunit gamma	0	0	7	7
Calcium/calmodulin-dependent protein kinase type II subunit delta	0	0	7	7
Dual specificity tyrosine-phosphorylation-regulated kinase 1A	0	1	7	8
Activin receptor type-2B	0	0	7	7
Bone morphogenetic protein receptor type-2	0	0	7	7
Protein-tyrosine kinase 6	0	1	7	8
cGMP-dependent protein kinase 1	0	0	7	7
Cyclin-dependent kinase 13	0	0	7	7
Calcium/calmodulin-dependent protein kinase type 1	0	0	2	2
Inhibitor of nuclear factor kappa-B kinase subunit epsilon	0	0	7	7
Protein-tyrosine kinase 2-beta	0	0	7	7
Maternal embryonic leucine zipper kinase	0	0	7	7
Structural maintenance of chromosomes protein 1A	0	0	6	6
Chromodomain-helicase-DNA-binding protein 4	0	0	6	6
Lysine--tRNA ligase	0	1	0	1
Peroxisomal acyl-coenzyme A oxidase 1	0	0	6	6
Cyclin-dependent kinase 10	0	0	1	1
Serine/threonine-protein kinase D1	0	1	4	5
Serine/threonine-protein kinase 38	0	0	4	4
Receptor tyrosine-protein kinase erbB-4	0	0	2	2
Ribosomal protein S6 kinase alpha-2	0	0	2	2
Ephrin type-A receptor 7	0	0	6	6
Delta(24)-sterol reductase	0	0	7	7
Ribosomal protein S6 kinase alpha-1	0	1	7	8
Dual specificity testis-specific protein kinase 1	0	0	7	7
Myosin light chain kinase, smooth muscle	0	0	7	7
Mitogen-activated protein kinase 11	0	1	7	8
Serine/threonine-protein kinase STK11	0	0	7	7
Rhodopsin kinase GRK1	0	1	2	3
NT-3 growth factor receptor	0	0	2	2
Serine/threonine-protein kinase N1	0	1	7	8
Serine/threonine-protein kinase N2	0	1	7	8
Calcium/calmodulin-dependent protein kinase type IV	0	0	7	7
Mitogen-activated protein kinase kinase kinase 11	0	0	7	7
BDNF/NT-3 growth factors receptor	0	1	2	3
Mitogen-activated protein kinase 6	0	0	2	2
Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform	0	0	2	2
Discoidin domain-containing receptor 2	0	2	7	9
AP2-associated protein kinase 1	0	0	7	7
Myosin light chain kinase 3	0	0	7	7
Uncharacterized aarF domain-containing protein kinase 5	0	0	5	5
Serine/threonine-protein kinase SBK1	0	0	2	2
Mitogen-activated protein kinase kinase kinase 19	0	0	2	2
Putative heat shock protein HSP 90-beta 2	0	0	7	7
Serine/threonine-protein kinase TNNI3K	0	0	2	2
Rab-like protein 3	0	0	4	4
Sigma intracellular receptor 2	0	2	0	2
Serine/threonine-protein kinase MRCK alpha	0	0	7	7
Macrophage-stimulating protein receptor	0	1	0	1
Serine/threonine-protein kinase MRCK gamma	0	0	6	6
Acyl-CoA dehydrogenase family member 10	0	0	7	7
Serine/threonine-protein kinase Nek5	0	0	2	2
Serine/threonine-protein kinase N3	0	0	6	6
Serine/threonine-protein kinase ULK3	0	0	7	7
Dual serine/threonine and tyrosine protein kinase	0	0	2	2
Mitogen-activated protein kinase kinase kinase 15	0	0	2	2
Uncharacterized protein FLJ45252	0	0	7	7
Acyl-CoA dehydrogenase family member 11	0	0	6	6
Serine/threonine-protein kinase/endoribonuclease IRE2	0	0	7	7
Serine/threonine-protein kinase MARK2	0	0	7	7
ATP-dependent RNA helicase DHX30	0	0	3	3
Serine/threonine-protein kinase TAO1	0	0	7	7
STE20-related kinase adapter protein alpha	0	0	7	7
Myosin-14	0	0	7	7
AarF domain-containing protein kinase 1	0	0	7	7
Serine/threonine-protein kinase tousled-like 2	0	0	2	2
Serine/threonine-protein kinase 32C	0	0	2	2
Serine/threonine-protein kinase pim-3	0	0	2	2
ATP-dependent RNA helicase DDX42	0	0	6	6
Serine/threonine-protein kinase VRK2	0	0	2	2
Myosin light chain kinase family member 4	0	0	2	2
Homeodomain-interacting protein kinase 1	0	0	2	2
Calcium/calmodulin-dependent protein kinase type 1D	0	0	2	2
Mitogen-activated protein kinase kinase kinase kinase 3	0	1	7	8
Cyclin-dependent kinase-like 3	0	0	2	2
MAP kinase-activated protein kinase 5	0	1	6	7
Serine/threonine-protein kinase BRSK2	0	0	2	2
Serine/threonine-protein kinase NIM1	0	0	2	2
Serine/threonine-protein kinase ULK2	0	0	2	2
Misshapen-like kinase 1	0	0	5	5
Serine/threonine-protein kinase DCLK2	0	0	2	2
Calcium/calmodulin-dependent protein kinase kinase 1	0	0	2	2
Casein kinase I isoform alpha-like	0	0	2	2
Mixed lineage kinase domain-like protein	0	0	1	1
Homeodomain-interacting protein kinase 4	0	0	2	2
Myosin-IIIa	0	0	2	2
Ankyrin repeat and protein kinase domain-containing protein 1	0	0	2	2
Serine/threonine-protein kinase Nek11	0	0	2	2
Atypical kinase COQ8A, mitochondrial	0	0	7	7
Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma	0	0	7	7
Mitogen-activated protein kinase 15	0	0	7	7
Serine/threonine-protein kinase Nek9	0	0	7	7
Serine/threonine-protein kinase BRSK1	0	0	2	2
Serine/threonine-protein kinase 35	0	0	2	2
Serine/threonine-protein kinase Nek7	0	0	3	3
Rhodopsin kinase GRK7	0	0	2	2
Serine/threonine-protein kinase 32A	0	0	2	2
Myosin-IIIb	0	0	2	2
ATP-dependent RNA helicase DDX1	0	0	7	7
Dual specificity tyrosine-phosphorylation-regulated kinase 2	0	0	2	2
Cyclin-dependent kinase-like 2	0	0	2	2
Mitogen-activated protein kinase kinase kinase kinase 1	0	0	7	7
Serine/threonine-protein kinase Sgk3	0	0	2	2
Atypical kinase COQ8B, mitochondrial	0	0	2	2
MAP/microtubule affinity-regulating kinase 4	0	0	6	6
Calcium/calmodulin-dependent protein kinase type 1G	0	0	3	3
Serine/threonine-protein kinase Nek1	0	0	7	7
Cyclin-dependent kinase 15	0	0	2	2
PAS domain-containing serine/threonine-protein kinase	0	0	6	6
Calcium/calmodulin-dependent protein kinase kinase 2	0	0	7	7
EKC/KEOPS complex subunit TP53RK	0	0	7	7
Dual specificity testis-specific protein kinase 2	0	0	5	5
SRSF protein kinase 1	0	0	2	2
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase	0	2	7	9
Mitogen-activated protein kinase kinase kinase 5	0	0	7	7
Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha	0	0	2	2
Mitogen-activated protein kinase kinase kinase 3	0	0	7	7
Eukaryotic translation initiation factor 2-alpha kinase 1	0	0	7	7
Serine/threonine-protein kinase RIO1	0	0	2	2
MAP kinase-interacting serine/threonine-protein kinase 1	0	0	2	2
Serine/threonine-protein kinase RIO2	0	0	2	2
Cyclin-dependent kinase 19	0	0	2	2
Transient receptor potential cation channel subfamily M member 6	0	0	2	2
Testis-specific serine/threonine-protein kinase 1	0	0	2	2
Serine/threonine-protein kinase 33	0	0	2	2
Nucleolar GTP-binding protein 1	0	0	7	7
Serine/threonine-protein kinase D2	0	0	7	7
Serine/threonine-protein kinase DCLK3	0	0	2	2
NUAK family SNF1-like kinase 2	0	0	6	6
RNA cytidine acetyltransferase	0	0	7	7
Serine/threonine-protein kinase SIK2	0	1	7	8
Myosin light chain kinase 2, skeletal/cardiac muscle	0	0	2	2
STE20-like serine/threonine-protein kinase	0	0	7	7
Serine/threonine-protein kinase TAO3	0	0	7	7
Homeodomain-interacting protein kinase 2	0	0	2	2
Tyrosine-protein kinase Srms	0	0	2	2
Homeodomain-interacting protein kinase 3	0	0	2	2
Serine/threonine-protein kinase PLK3	0	1	2	3
dCTP pyrophosphatase 1	0	2	7	9
Dual specificity protein kinase CLK4	0	0	6	6
Echinoderm microtubule-associated protein-like 4	0	1	0	1
Serine/threonine-protein kinase Nek6	0	1	2	3
Casein kinase I isoform gamma-1	0	0	7	7
Serine/threonine-protein kinase PAK 6	0	0	4	4
SNF-related serine/threonine-protein kinase	0	0	2	2
Serine/threonine-protein kinase LATS2	0	0	2	2
Serine/threonine-protein kinase 36	0	0	2	2
Phenylalanine--tRNA ligase beta subunit	0	0	7	7
Isoleucine--tRNA ligase, mitochondrial	0	0	6	6
BMP-2-inducible protein kinase	0	0	7	7
Obg-like ATPase 1	0	0	6	6
Midasin	0	0	7	7
Aurora kinase A-interacting protein	0	1	0	1
Interleukin-1 receptor-associated kinase 4	0	0	7	7
Serine/threonine-protein kinase 32B	0	0	2	2
Mitogen-activated protein kinase kinase kinase 20	0	0	7	7
Cyclin-dependent kinase 12	0	0	7	7
Serine/threonine-protein kinase PLK2	0	1	2	3
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13	0	0	6	6
Serine/threonine-protein kinase MARK1	0	0	2	2
Serine/threonine-protein kinase pim-2	0	0	4	4
Serine/threonine-protein kinase PAK 5	0	0	2	2
Serine/threonine-protein kinase 26	0	0	7	7
eIF-2-alpha kinase GCN2	0	0	2	2
Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial	0	0	7	7
Serine/threonine-protein kinase NLK	0	0	7	7
Phosphatidylinositol 4-kinase beta	0	0	2	2
Serine/threonine-protein kinase 17A	0	0	2	2
STE20/SPS1-related proline-alanine-rich protein kinase	0	0	2	2
Ephrin type-A receptor 6	0	0	2	2
5'-AMP-activated protein kinase subunit gamma-2	0	0	7	7
Serine/threonine-protein kinase TBK1	0	0	7	7
Septin-9	0	0	7	7
Death-associated protein kinase 2	0	0	2	2
Ribosomal protein S6 kinase alpha-6	0	0	7	7
TRAF2 and NCK-interacting protein kinase	0	0	7	7
Serine/threonine-protein kinase tousled-like 1	0	0	2	2
Serine/threonine-protein kinase TAO2	0	0	7	7
Long-chain-fatty-acid--CoA ligase 5	0	0	6	6
ALK tyrosine kinase receptor	0	4	3	7
SRSF protein kinase 3	0	0	2	2
Serine/threonine-protein kinase ICK	0	0	6	6
Cyclin-dependent kinase 11A	0	0	2	2
Aurora kinase C	0	0	2	2
Calcium/calmodulin-dependent protein kinase type II subunit alpha	0	0	2	2
RAC-gamma serine/threonine-protein kinase	0	1	7	8
Serine/threonine-protein kinase 38-like	0	0	5	5
Microtubule-associated serine/threonine-protein kinase 1	0	0	2	2
Serine/threonine-protein kinase SIK3	0	1	7	8
Mitogen-activated protein kinase kinase kinase 2	0	0	7	7
Thyroid hormone receptor-associated protein 3	0	0	6	6
Dual specificity tyrosine-phosphorylation-regulated kinase 1B	0	0	4	4
Mitogen-activated protein kinase kinase kinase kinase 5	0	0	7	7
Receptor-interacting serine/threonine-protein kinase 3	0	0	7	7
Serine/threonine-protein kinase MRCK beta	0	0	7	7
Interleukin-1 receptor-associated kinase 3	0	0	7	7
Serine/threonine-protein kinase 24	0	0	5	5
Casein kinase I isoform gamma-3	0	0	7	7
Mitogen-activated protein kinase kinase kinase 4	0	0	7	7
LMP1 [Human herpesvirus 4]	0	0	0	3
nuclear receptor coactivator 1 isoform 1 [Homo sapiens]	0	3	0	3
transactivating tegument protein VP16 [Human herpesvirus 1]	0	3	0	3
nuclear receptor coactivator 3 isoform a	0	3	0	3
Thymidine kinase 2, mitochondrial	0	1	0	1
Thymidine kinase, cytosolic	0	3	0	4
Thymidine kinase	0	1	0	1
Thymidylate synthase	0	2	0	3
Thymidine kinase	0	1	0	1
Probable deoxycytidylate deaminase	0	0	0	1
Cytidine deaminase	0	1	0	2
D(1A) dopamine receptor	2	0	0	2
E3 ubiquitin-protein ligase Mdm2	1	4	1	6
Enoyl-[acyl-carrier-protein] reductase [NADH]	0	1	0	1
Thymidine kinase	0	1	0	1
Deoxynucleoside kinase	0	1	0	1
Deoxycytidine kinase	0	0	0	1
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	0	1	0	1
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha	0	1	0	1
Phosphatidylinositol 3-kinase regulatory subunit alpha	0	3	1	4
Protein kinase C zeta type	0	1	5	6
Serine-protein kinase ATM	0	1	0	1
Serine/threonine-protein kinase ATR	0	0	1	1
MAP kinase-activated protein kinase 3	0	0	1	1
Eukaryotic peptide chain release factor GTP-binding subunit ERF3B	0	0	3	3
Phosphoinositide 3-kinase regulatory subunit 5	0	1	0	1
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform	0	1	0	1
GALC protein	1	0	0	1
huntingtin isoform 2	4	0	0	4
Voltage-dependent L-type calcium channel subunit alpha-1F	0	1	0	1
Proto-oncogene tyrosine-protein kinase Src	0	1	1	2
Neuronal proto-oncogene tyrosine-protein kinase Src	0	0	0	1
Proto-oncogene tyrosine-protein kinase LCK	0	2	0	2
Quinolone resistance protein NorA	0	1	0	1
Cytochrome P450 2A6	0	2	0	2
Myosin light chain kinase, smooth muscle	0	0	1	1
Angiotensin-converting enzyme	0	1	0	1
Potassium voltage-gated channel subfamily E member 1	0	2	0	2
Tyrosine-protein kinase Blk	0	1	0	1
Cytochrome P450 2B6	0	1	0	1
Potassium voltage-gated channel subfamily KQT member 1	0	2	0	2
Tubulin alpha-1A chain	0	0	1	1
DNA-dependent protein kinase catalytic subunit	0	2	0	2
Myelin transcription factor 1	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1D	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1S	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1C	0	1	0	1
Sodium channel protein type 5 subunit alpha	0	2	0	2
Breakpoint cluster region protein	0	1	0	1
Protein cereblon	0	6	4	16
Potassium voltage-gated channel subfamily D member 3	0	2	0	2
NF-kappa-B essential modulator	0	1	0	1
Transient receptor potential cation channel subfamily A member 1	0	1	2	3
Glutathione reductase, mitochondrial	0	1	0	2
Kelch-like ECH-associated protein 1	0	1	3	4
Nuclear factor erythroid 2-related factor 2	0	1	4	7
prostaglandin E2 receptor EP2 subtype	1	0	0	1
Solute carrier family 22 member 2	0	1	0	2
Solute carrier family 22 member 1	0	0	0	2
Solute carrier organic anion transporter family member 1A5	0	0	0	1
Prostaglandin E2 receptor EP3 subtype	0	1	0	1
Prostaglandin E2 receptor EP4 subtype	0	1	0	1
Prostaglandin E2 receptor EP1 subtype	0	2	1	3
Prostaglandin E2 receptor EP1 subtype	0	1	0	1
Prostaglandin E2 receptor EP4 subtype	0	2	1	3
Prostaglandin F2-alpha receptor	0	0	1	1
Prostaglandin E2 receptor EP4 subtype	0	1	1	2
Prostaglandin E2 receptor EP3 subtype	0	2	1	3
Prostaglandin E2 receptor EP2 subtype	0	2	1	3
Prostacyclin receptor	0	2	1	3
Solute carrier organic anion transporter family member 2A1	0	0	0	1
Solute carrier family 22 member 7	0	0	0	2
Prostaglandin E2 receptor EP2 subtype	0	1	0	1
Prostaglandin E2 receptor EP2 subtype	0	1	1	2
Solute carrier family 22 member 20	0	2	0	2
Solute carrier family 22 member 8	0	0	0	3
Solute carrier family 22 member 6	0	2	0	2
Solute carrier family 22 member 7	0	0	0	1
Solute carrier organic anion transporter family member 2A1	0	0	0	1
Solute carrier family 22 member 11	0	0	0	3
Solute carrier organic anion transporter family member 1B2	0	0	0	1
Solute carrier family 22 member 7	0	0	0	2
Gasdermin-D	0	1	0	1
Gasdermin-D	0	1	0	1
Chain A, PFV integrase	0	1	0	1
Chain A, PFV integrase	0	1	0	1
Chain A, PFV integrase	0	1	0	1
Cytochrome P450 2C8	0	3	0	3
UDP-glucuronosyltransferase 1A1	0	1	0	3
Integrase	0	0	1	1
Sigma non-opioid intracellular receptor 1	0	3	0	3
Vesicular acetylcholine transporter	0	1	0	1
Histone deacetylase 8	0	2	0	2
Bromodomain-containing protein 4	0	5	1	6
Leukotriene A-4 hydrolase	0	4	0	4
Tissue factor	0	2	0	2
Histone deacetylase-like amidohydrolase	0	4	1	5
NAD-dependent protein deacetylase sirtuin-1	0	3	1	6
Histone deacetylase	0	2	0	2
Nuclear receptor corepressor 2	0	4	0	4
Chain A, Troponin C, slow skeletal and cardiac muscles	0	0	1	1
Chain A, Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	0	0	1	1
Chain A, POLYMERASE PA	0	1	0	1
Chain A, Polymerase Pa	0	1	0	1
Chain A, Polymerase Pa	0	1	0	1
Chain A, Polymerase Pa	0	1	0	1
Chain A, Polymerase Pa	0	1	0	1
Genome polyprotein	0	1	0	1
lysosomal alpha-glucosidase preproprotein	2	0	0	2
galactokinase	2	0	0	2
pyruvate kinase PKM isoform a	2	0	0	2
nuclear factor NF-kappa-B p105 subunit isoform 1	1	0	1	2
POsterior Segregation	0	0	2	2
Prostaglandin E synthase	0	1	0	1
Polycomb protein EED	0	0	1	1
NAD kinase	0	2	1	3
Dihydrofolate reductase	0	2	0	4
Urokinase-type plasminogen activator	0	2	0	2
Tissue-type plasminogen activator	0	1	0	1
Polymerase acidic protein	0	1	0	1
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1	0	3	0	3
Plasminogen activator inhibitor 1	0	1	0	1
Heme oxygenase 1	0	1	0	1
Urokinase-type plasminogen activator	0	1	0	1
72 kDa type IV collagenase	0	3	0	3
Matrilysin	0	1	0	1
60 kDa chaperonin	0	2	0	2
Enoyl-[acyl-carrier-protein] reductase [NADH] FabI	0	2	0	2
Alpha-amylase 1A	0	2	0	2
Apoptosis regulator Bcl-2	0	3	1	4
Microtubule-associated protein tau	0	1	0	1
60 kDa heat shock protein, mitochondrial	0	2	0	2
Glucose-6-phosphate 1-dehydrogenase	0	1	0	1
CPG DNA methylase	0	1	0	1
Lethal factor	0	3	0	3
Phosphoglycerate mutase 1	0	1	0	1
Heme oxygenase 2	0	1	0	1
Sodium-dependent noradrenaline transporter	0	4	2	6
DNA (cytosine-5)-methyltransferase 1	0	2	0	2
Signal transducer and activator of transcription 1-alpha/beta	0	0	1	1
DNA repair protein RAD52 homolog	0	1	0	1
Matrix metalloproteinase-14	0	2	0	2
4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase FUT6	0	1	0	1
Squalene monooxygenase	0	1	0	1
6-phosphogluconate dehydrogenase, decarboxylating	0	2	0	2
BH3-interacting domain death agonist	0	1	0	1
10 kDa heat shock protein, mitochondrial	0	2	0	2
Bcl-2-like protein 1	0	2	0	2
Induced myeloid leukemia cell differentiation protein Mcl-1	0	2	0	2
Histone acetyltransferase p300	0	1	0	1
Alpha-(1,3)-fucosyltransferase 7	0	1	0	1
CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1	0	1	0	1
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	0	3	1	4
Bcl-2-related protein A1	0	1	0	1
Thiosulfate sulfurtransferase	0	2	0	2
60 kDa chaperonin	0	2	0	2
Dual specificity tyrosine-phosphorylation-regulated kinase 1A	0	1	0	1
10 kDa chaperonin	0	2	0	2
3-oxoacyl-[acyl-carrier-protein] reductase	0	1	0	1
CREB-binding protein	0	1	1	2
Histone acetyltransferase KAT2B	0	1	0	1
Bcl-2-like protein 2	0	1	0	1
Bcl2-associated agonist of cell death	0	1	0	1
Histone acetyltransferase KAT5	0	1	0	1
3-oxoacyl-acyl-carrier protein reductase	0	2	0	2
Beta-hydroxyacyl-ACP dehydratase precursor (Fatty acid synthesis protein)	0	2	0	2
Bcl-2-like protein 10	0	1	0	1
Zinc finger protein mex-5	0	0	2	2
Regulatory protein E2	0	0	1	1
ATP-dependent translocase ABCB1	0	1	0	1
DNA topoisomerase 1	0	1	0	2
Polyunsaturated fatty acid lipoxygenase ALOX15	0	2	0	2
DNA topoisomerase 2	0	0	0	1
ATP-dependent translocase ABCB1	0	1	0	1
Serum paraoxonase/arylesterase 1	0	1	0	1
Caspase-3	0	1	0	1
DNA topoisomerase 2-alpha	0	0	0	1
Glutamate receptor ionotropic, NMDA 2D	0	0	0	2
Tubulin beta-2B chain	0	2	0	2
Similar to alpha-tubulin isoform 1	0	2	0	2
Similar to alpha-tubulin isoform 1	0	2	0	2
Glutamate receptor ionotropic, NMDA 3B	0	0	0	2
Glutamate receptor ionotropic, NMDA 3A	0	0	0	2
thyrotropin-releasing hormone receptor	4	0	0	4
Menin	0	0	1	1
Lecithin retinol acyltransferase	0	2	0	2
30S ribosomal protein S6	0	2	0	2
30S ribosomal protein S7	0	2	0	2
50S ribosomal protein L15	0	2	0	2
50S ribosomal protein L10	0	2	0	2
50S ribosomal protein L11	0	2	0	2
50S ribosomal protein L7/L12	0	2	0	2
50S ribosomal protein L19	0	2	0	2
50S ribosomal protein L1	0	2	0	2
50S ribosomal protein L20	0	2	0	2
50S ribosomal protein L27	0	2	0	2
50S ribosomal protein L28	0	2	0	2
50S ribosomal protein L29	0	2	0	2
50S ribosomal protein L31	0	2	0	2
50S ribosomal protein L31 type B	0	2	0	2
50S ribosomal protein L32	0	2	0	2
50S ribosomal protein L33	0	2	0	2
50S ribosomal protein L34	0	2	0	2
50S ribosomal protein L35	0	2	0	2
50S ribosomal protein L36	0	2	0	2
30S ribosomal protein S10	0	2	0	2
30S ribosomal protein S11	0	2	0	2
30S ribosomal protein S12	0	2	0	2
30S ribosomal protein S13	0	2	0	2
30S ribosomal protein S16	0	2	0	2
30S ribosomal protein S18	0	2	0	2
30S ribosomal protein S19	0	2	0	2
30S ribosomal protein S20	0	2	0	2
30S ribosomal protein S2	0	2	0	2
30S ribosomal protein S3	0	2	0	2
30S ribosomal protein S4	0	2	0	2
30S ribosomal protein S5	0	2	0	2
30S ribosomal protein S8	0	2	0	2
30S ribosomal protein S9	0	2	0	2
50S ribosomal protein L13	0	2	0	2
50S ribosomal protein L14	0	2	0	2
50S ribosomal protein L16	0	2	0	2
50S ribosomal protein L23	0	2	0	2
30S ribosomal protein S15	0	2	0	2
50S ribosomal protein L17	0	2	0	2
50S ribosomal protein L21	0	2	0	2
50S ribosomal protein L30	0	2	0	2
50S ribosomal protein L6	0	2	0	2
30S ribosomal protein S14	0	2	0	2
30S ribosomal protein S17	0	2	0	2
30S ribosomal protein S1	0	2	0	2
50S ribosomal protein L18	0	2	0	2
50S ribosomal protein L2	0	2	0	2
50S ribosomal protein L3	0	2	0	2
50S ribosomal protein L24	0	2	0	2
50S ribosomal protein L4	0	2	0	2
50S ribosomal protein L22	0	2	0	2
50S ribosomal protein L5	0	2	0	2
30S ribosomal protein S21	0	2	0	2
50S ribosomal protein L25	0	2	0	2
50S ribosomal protein L36 2	0	2	0	2
Protein Rev	0	1	1	2
Aminoglycoside 3'-phosphotransferase	0	0	0	2
P53	2	0	0	2
alpha-galactosidase	4	0	0	4
beta-2 adrenergic receptor	1	0	0	1
ClpP	3	0	0	3
POU domain, class 2, transcription factor 2	0	0	0	1
Transitional endoplasmic reticulum ATPase	0	1	0	1
Purine nucleoside phosphorylase	0	0	1	1
Chain A, Bromodomain-containing Protein 4	0	0	1	1
Chain A, BROMODOMAIN-CONTAINING PROTEIN 2	0	1	0	1
Chain A, BROMODOMAIN-CONTAINING PROTEIN 2	0	1	0	1
Bromodomain-containing protein 2	0	2	1	3
cAMP-specific 3',5'-cyclic phosphodiesterase 4B	0	2	0	3
Bromodomain-containing protein 3	0	2	1	3
Bromodomain testis-specific protein	0	1	0	1
ATPase family AAA domain-containing protein 2	0	0	1	1
Eukaryotic initiation factor 4A-III	0	1	1	2
Eukaryotic initiation factor 4A-I	0	1	0	1
Eukaryotic initiation factor 4A-I	0	1	0	1
Eukaryotic initiation factor 4A-II	0	1	0	1
ATP-dependent RNA helicase DHX29	0	1	0	1
Splicing factor 3B subunit 3	0	2	0	2
Cereblon isoform 4	0	4	0	4
DNA-binding protein Ikaros	0	0	2	7
DNA damage-binding protein 1	0	3	2	5
Zinc finger protein Aiolos	0	0	2	2
N-formyl peptide receptor 2	0	1	0	1
Chain A, protease	0	1	0	1
Chain B, protease	0	1	0	1
Chain A, protease	0	0	1	1
Chain B, protease	0	0	1	1
Chain A, protease	0	0	1	1
Chain B, protease	0	0	1	1
Chain A, protease	0	0	1	1
Chain B, protease	0	0	1	1
Chain A, protease	0	0	1	1
Chain B, protease	0	0	1	1
Chain A, protease	0	0	1	1
Chain B, protease	0	0	1	1
Chain A, Protease	0	1	0	1
Chain B, Protease	0	1	0	1
Chain A, Protease	0	1	0	1
Chain B, Protease	0	1	0	1
Chain A, Protease	0	1	0	1
Chain B, Protease	0	1	0	1
Chain A, PROTEASE RETROPEPSIN	0	1	0	1
Chain B, PROTEASE RETROPEPSIN	0	1	0	1
Chain A, Protease Retropepsin	0	1	0	1
Chain B, Protease Retropepsin	0	1	0	1
Chain A, Protease Retropepsin	0	1	0	1
Chain B, Protease Retropepsin	0	1	0	1
Albumin	0	2	1	5
Gag-Pol polyprotein	0	1	0	1
Gag-Pol polyprotein	0	1	0	1
Gag-Pol polyprotein	0	1	0	1
Gag-Pol polyprotein	0	2	0	2
Alpha-1B adrenergic receptor	0	5	0	5
Alpha-1D adrenergic receptor	0	3	0	3
Gag-Pol polyprotein	0	1	0	1
Alpha-1A adrenergic receptor	0	4	0	4
Protease	0	4	2	6
CAAX prenyl protease 1 homolog	0	1	0	1
Plasmepsin V	0	1	0	1
Protease	0	4	2	6
Chain A, Antigen Cd11a (p180)	0	1	0	1
PINK1	1	0	0	1
isocitrate dehydrogenase 1, partial	1	0	0	1
bcl-2-related protein A1	0	2	0	2
3-hydroxy-3-methylglutaryl-coenzyme A reductase	0	2	0	2
Integrin beta-2	0	1	0	1
Intercellular adhesion molecule 1	0	1	0	1
Insulin receptor	0	1	0	1
Androgen receptor	0	4	0	4
Integrin alpha-L	0	1	1	2
Substance-K receptor	0	2	0	2
Adenosine receptor A1	0	2	0	2
3-hydroxy-3-methylglutaryl-coenzyme A reductase	0	1	0	1
Sodium-dependent dopamine transporter	0	4	0	4
Lanosterol 14-alpha demethylase	0	1	0	1
Rap guanine nucleotide exchange factor 4	2	0	0	2
Acyl-CoA:cholesterol acyltransferase	0	1	0	1
Chain B, DIHYDROFOLATE REDUCTASE	0	0	1	1
Chain B, DIHYDROFOLATE REDUCTASE	0	0	1	1
Chain B, DIHYDROFOLATE REDUCTASE	0	0	1	1
acid sphingomyelinase	2	0	0	2
Thymidylate synthase	0	1	0	1
Thymidylate synthase	0	1	0	1
transcriptional regulator ERG isoform 3	1	0	0	1
muscleblind-like protein 1 isoform 1	4	0	0	4
caspase-1 isoform alpha precursor	1	0	0	1
Toll-like receptor 4	0	1	0	1
Fatty-acid amide hydrolase 1	0	1	0	1
Bile salt export pump	0	2	0	2
ATP-binding cassette sub-family C member 3	0	1	0	2
Dihydrofolate reductase	0	2	0	3
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	2	0	3
Thymidylate synthase	0	1	0	1
Thymidylate synthase	0	2	0	2
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
5-hydroxytryptamine receptor 2C	0	1	0	2
High mobility group protein B1	0	0	1	1
Dihydrofolate reductase	0	1	0	1
Thymidylate synthase	0	1	0	1
Dihydrofolate reductase	0	2	2	4
Glucose-6-phosphate 1-dehydrogenase	0	1	0	1
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Folate receptor beta	0	1	0	1
5-hydroxytryptamine receptor 2A	0	1	0	1
Cytochrome P450 11B1, mitochondrial	0	1	0	1
Folate receptor alpha	0	1	0	1
Dihydrofolate reductase	0	2	0	2
Histidine decarboxylase	0	1	0	1
Trifunctional purine biosynthetic protein adenosine-3	0	1	0	1
Bifunctional purine biosynthesis protein ATIC	0	2	0	2
Delta-type opioid receptor	0	1	0	2
Mu-type opioid receptor	0	1	0	1
Kappa-type opioid receptor	0	1	0	1
Reduced folate transporter	0	2	0	2
Folylpolyglutamate synthase, mitochondrial	0	1	0	3
Caspase-7	1	0	0	1
Solute carrier organic anion transporter family member 1A3	0	0	0	2
Dihydrofolate reductase	0	1	0	1
Pteridine reductase 1	0	1	0	1
Folylpolyglutamate synthase, mitochondrial	0	1	0	3
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Canalicular multispecific organic anion transporter 1	0	1	0	2
Trifunctional purine biosynthetic protein adenosine-3	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	1	0	1
ATP-binding cassette sub-family C member 11	0	0	0	1
Proton-coupled folate transporter	0	1	0	1
Multidrug resistance associated protein	0	1	0	2
Protein-arginine deiminase type-4	0	1	0	1
Platelet-activating factor receptor	0	1	0	1
M-phase inducer phosphatase 1	0	1	0	1
Chain A, HEAT SHOCK PROTEIN 90	0	0	1	1
Chain A [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 1	0	1	0	1
Chain A [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 3	0	1	0	1
Chain A, Atp-dependent Molecular Chaperone Hsp82	0	0	1	1
Chain A, Atp-dependent Molecular Chaperone Hsp82	0	0	1	1
Chain B, Type 2 DNA topoisomerase 6 subunit B	0	0	1	1
Chain A, Virulence sensor histidine kinase phoQ	0	0	1	1
ATP-dependent molecular chaperone HSP82	0	2	1	3
Heat shock protein HSP 90-alpha	0	6	4	10
Virulence sensor histidine kinase PhoQ	0	0	1	1
ATP-dependent molecular chaperone HSC82	0	2	0	2
Carbonyl reductase [NADPH] 1	0	2	0	2
ATP-citrate synthase	0	1	0	1
Histamine H1 receptor	0	0	1	1
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial	0	1	0	1
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial	0	1	1	2
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 3, mitochondrial	0	1	0	1
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial	0	1	0	1
Proto-oncogene tyrosine-protein kinase Src	0	1	0	1
Histidine kinase	0	1	0	1
Presenilin-1	0	1	0	1
Presenilin-2	0	1	0	1
Gamma-secretase subunit APH-1B	0	1	0	1
Nicastrin	0	1	0	1
Gamma-secretase subunit APH-1A	0	1	0	1
Protein Tat	0	1	0	1
Protein Rev	0	1	0	1
Chain A, NAD-dependent deacetylase	0	1	0	1
Poly [ADP-ribose] polymerase 2	0	1	0	1
NAD-dependent histone deacetylase SIR2	0	1	0	1
Coagulation factor VII	0	1	0	1
Cytochrome P450 3A5	0	2	1	3
NAD-dependent protein deacetylase HST2	0	2	0	2
Fatty-acid amide hydrolase 1	0	1	0	1
NAD(+) hydrolase SARM1	0	1	0	1
NAD-dependent protein deacetylase sirtuin-2	0	2	1	3
NAD-dependent protein deacetylase sirtuin-6	0	1	0	1
NAD-dependent protein deacetylase sirtuin-3, mitochondrial	0	2	1	3
NAD-dependent protein deacylase sirtuin-5, mitochondrial	0	2	0	2
NAD-dependent protein deacetylase	0	1	0	1
Interstitial collagenase	0	2	1	3
Glutamate receptor 1	1	0	0	1
Glutamate receptor 3	1	0	0	1
Glutamate receptor 4	1	0	0	1
Chain A, G protein-coupled receptor kinase 6	0	0	1	1
Heat shock cognate 71 kDa protein	0	0	1	1
Adenosine receptor A3	0	1	0	1
Adenosine receptor A2b	0	1	0	1
Adenosine kinase	0	1	0	1
Histone-lysine N-methyltransferase, H3 lysine-79 specific	0	1	0	1
Protein Mdm4	0	2	0	2
E3 ubiquitin-protein ligase Mdm2	0	1	0	1
Delta-type opioid receptor	0	1	1	2
E3 ubiquitin-protein ligase Mdm2	0	1	0	1
Peptidyl-prolyl cis-trans isomerase D	0	1	0	1
Mu-type opioid receptor	0	0	1	1
Chain B, Cell division protein kinase 6	0	1	0	1
Chain B, Cell division protein kinase 6	0	1	0	1
Cyclin-T1	0	2	0	2
Cyclin-K	0	1	0	1
Acetylcholinesterase	0	1	0	1
G1/S-specific cyclin-E1	0	1	0	1
G1/S-specific cyclin-D2	0	1	0	1
G1/S-specific cyclin-D3	0	2	0	2
Cyclin-H	0	2	0	2
CDK-activating kinase assembly factor MAT1	0	1	0	1
Cyclin-A1	0	1	0	1
Protein kinase C gamma type	0	1	2	3
Chain A, CATHEPSIN D	0	1	0	1
Chain B, CATHEPSIN D	0	1	0	1
Chain A, PLASMEPSIN II	0	1	0	1
Chain E, ENDOTHIAPEPSIN	0	1	0	1
Chain E, RHIZOPUSPEPSIN	0	1	0	1
Chain E, ENDOTHIAPEPSIN	0	1	0	1
Chain E, ENDOTHIAPEPSIN	0	1	0	1
Chain E, RHIZOPUSPEPSIN	0	1	0	1
Chain E, RHIZOPUSPEPSIN	0	1	0	1
Pepsin A	0	2	0	2
Renin	0	2	0	2
Cathepsin D	0	3	0	4
Pro-cathepsin H	0	1	0	1
Candidapepsin-2	0	1	0	1
Pepsin A-5	0	1	0	1
Gag-Pro polyprotein	0	1	0	1
Cathepsin E	0	1	0	1
Plasmepsin-1	0	1	0	1
Plasmepsin-2	0	1	0	1
Cathepsin D	0	2	0	2
Disintegrin and metalloproteinase domain-containing protein 9	0	1	0	1
Plasmepsin 4	0	1	0	1
Cysteine protease	0	1	0	1
Chymotrypsin-C	0	2	0	2
Transporter	0	1	0	1
Ubiquitin carboxyl-terminal hydrolase isozyme L3	0	1	0	1
Ras-related C3 botulinum toxin substrate 1	0	0	1	1
Programmed cell death protein 1	0	1	0	1
E3 ubiquitin-protein ligase ZFP91	0	0	0	1
Programmed cell death 1 ligand 1	0	1	0	1
luciferase	0	0	0	1
Fatty acid-binding protein, liver	0	1	0	1
Progesterone receptor	0	2	0	3
Glucocorticoid receptor	0	1	1	2
Glucocorticoid receptor	0	0	1	1
Glycine receptor subunit alpha-1	0	4	0	4
Corticosteroid-binding globulin	0	1	0	1
Mineralocorticoid receptor	0	2	1	3
Glutamine synthetase	0	0	1	1
Glycine receptor subunit beta	0	4	0	4
Glycine receptor subunit alpha-2	0	4	0	4
Glycine receptor subunit alpha-3	0	4	0	4
Histamine H1 receptor	0	0	1	1
Nociceptin receptor	0	0	1	1
Cytochrome P450 2J2	0	1	0	1
Hypoxia-inducible factor 1-alpha	0	1	0	1
Chain A, APH(2')-Id	0	1	0	1
glucose-6-phosphate dehydrogenase	0	1	0	1
signal transducer and activator of transcription 6, interleukin-4 induced	1	0	0	1
DNA polymerase III, partial	1	0	0	1
hexokinase	0	1	0	1
interferon gamma precursor	0	0	0	1
Maltase-glucoamylase, intestinal	0	1	0	1
B2 bradykinin receptor	0	1	0	1
Prothrombin	0	1	0	1
Chymotrypsin-like elastase family member 1	0	1	0	1
Beta-lactamase	0	1	0	1
Protein E6	0	1	0	1
Phospholipase A2	0	1	0	1
Beta-lactamase	0	1	0	1
Epoxide hydrolase 1	0	1	0	1
Trypsin-1	0	1	0	1
Trypsin-2	0	1	0	1
Stromelysin-1	0	1	0	1
5-hydroxytryptamine receptor 1A	0	0	1	1
Heterogeneous nuclear ribonucleoprotein A1	0	0	1	1
Adenosine receptor A3	0	3	0	3
Calmodulin-1	0	1	0	1
Lysosomal alpha-glucosidase	0	1	0	1
Malate dehydrogenase	0	1	0	1
Solute carrier family 2, facilitated glucose transporter member 2	0	1	0	1
Polyunsaturated fatty acid 5-lipoxygenase	0	1	0	1
Sucrase-isomaltase, intestinal	0	1	0	1
Tyrosinase	0	2	0	2
Matrix metalloproteinase-9	0	2	0	2
Cytochrome P450 11B1, mitochondrial	0	1	0	1
Polyunsaturated fatty acid lipoxygenase ALOX15	0	1	0	2
Aldo-keto reductase family 1 member B1	0	1	0	1
Polyunsaturated fatty acid lipoxygenase ALOX12	0	1	0	2
5-hydroxytryptamine receptor 1A	0	3	0	4
Solute carrier family 2, facilitated glucose transporter member 4	0	1	0	1
Amine oxidase [flavin-containing] A	0	1	0	1
5'-nucleotidase	0	1	0	1
D(4) dopamine receptor	0	1	0	1
Glyceraldehyde-3-phosphate dehydrogenase, glycosomal	0	1	0	1
Sodium-dependent dopamine transporter	0	1	0	1
Sodium- and chloride-dependent GABA transporter 1	0	1	0	1
C-X-C chemokine receptor type 1	0	1	0	1
Cytosol aminopeptidase	0	1	0	1
ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1	0	2	0	2
Nitric oxide synthase, inducible	0	3	0	3
Vasopressin V2 receptor	0	1	0	1
Sodium- and chloride-dependent GABA transporter 2	0	1	0	1
Sodium- and chloride-dependent GABA transporter 3	0	1	0	1
Sodium-dependent serotonin transporter	0	1	0	1
Bifunctional epoxide hydrolase 2	0	1	0	1
Trypsin-3	0	1	0	1
Prostaglandin G/H synthase 2	0	1	0	1
Macrophage metalloelastase	0	1	0	1
Glutathione reductase	0	1	0	1
Collagenase 3	0	1	0	1
1-deoxy-D-xylulose 5-phosphate reductoisomerase	0	1	0	1
Sodium- and chloride-dependent betaine transporter	0	1	0	1
Aldo-keto reductase family 1 member A1	0	1	0	1
Aldo-keto reductase family 1 member A1	0	1	0	1
C-C chemokine receptor type 4	0	1	0	1
Oligo-1,6-glucosidase IMA1	0	1	0	1
Monocarboxylate transporter 1	0	1	0	1
Amine oxidase [flavin-containing] B	0	1	0	1
Anthrax toxin receptor 2	0	1	0	1
Aldo-keto reductase family 1 member B1	0	1	0	1
Heat shock factor protein 1	0	1	0	1
Sorbitol dehydrogenase	0	1	0	1
cGMP-dependent 3',5'-cyclic phosphodiesterase	0	1	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B	0	1	0	1
Lactoylglutathione lyase	0	2	0	2
ELAV-like protein 3	0	1	0	1
ELAV-like protein 1	0	1	0	1
Probable maltase-glucoamylase 2	0	1	0	1
Monocarboxylate transporter 2	0	1	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C	0	1	0	1
Prostaglandin G/H synthase 1	0	1	0	1
Aldo-keto reductase family 1 member C21	0	2	0	2
Carbonic anhydrase 13	0	1	0	1
Phosphodiesterase	0	1	0	1
G-protein coupled receptor 35	0	1	1	2
Hypoxia-inducible factor 1-alpha inhibitor	0	1	0	1
phosphoglycerate kinase	1	0	0	1
Chain A, Troponin C, slow skeletal and cardiac muscles	0	0	1	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
M18 aspartyl aminopeptidase	0	1	0	1
cathepsin L1	0	1	0	1
hexokinase-4 isoform 1	1	0	0	1
glucokinase regulatory protein	1	0	0	1
FAD-linked sulfhydryl oxidase ALR	0	0	0	1
Vif	0	1	0	1
DNA dC->dU-editing enzyme APOBEC-3G isoform 1	0	1	0	1
transcription factor p65 isoform 1	0	0	1	1
serine/threonine-protein kinase 33 isoform a	0	0	1	1
Aryl hydrocarbon receptor	0	1	0	1
Estrogen receptor beta	0	0	1	1
Myc proto-oncogene protein	0	1	0	2
Luciferin 4-monooxygenase	0	1	1	2
Neuronal acetylcholine receptor subunit alpha-4	0	1	0	1
DNA polymerase alpha catalytic subunit	0	1	0	1
Tyrosinase	0	3	0	3
Ornithine decarboxylase	0	1	0	1
Neuronal acetylcholine receptor subunit beta-2	0	1	0	1
Estrogen receptor	0	0	1	1
Endothelin receptor type B	1	0	0	1
Endothelin-1 receptor	1	0	0	1
Cannabinoid receptor 1	0	1	0	1
Alpha-glucosidase MAL12	0	1	0	1
Squalene synthase	0	1	0	1
N1L	0	1	0	1
NAD(P)H dehydrogenase [quinone] 1	0	0	0	4
Lysosomal alpha-glucosidase	0	1	0	1
Transient receptor potential cation channel subfamily A member 1	0	1	0	1
CDGSH iron-sulfur domain-containing protein 1	0	1	0	1
Free fatty acid receptor 1	0	0	1	1
Glutamate receptor ionotropic, NMDA 2D	0	0	1	1
Glutamate receptor ionotropic, NMDA 3B	0	0	1	1
Muscarinic acetylcholine receptor M1	0	0	1	1
Muscarinic acetylcholine receptor M3	0	0	1	1
Muscarinic acetylcholine receptor M4	0	0	1	1
Muscarinic acetylcholine receptor M5	0	0	1	1
Muscarinic acetylcholine receptor M2	0	0	1	1
Carnitine O-palmitoyltransferase 2, mitochondrial	0	1	0	1
Amine oxidase [flavin-containing] B	0	1	0	1
Amine oxidase [flavin-containing] A	0	1	0	1
Catechol O-methyltransferase	0	0	1	1
Peroxisome proliferator-activated receptor alpha	0	1	1	2
Carnitine O-palmitoyltransferase 2, mitochondrial	0	1	0	1
Thromboxane-A synthase	0	1	0	1
Peroxisome proliferator-activated receptor gamma	0	2	2	5
Cannabinoid receptor 2	0	0	1	1
Carnitine O-palmitoyltransferase 1, liver isoform	0	1	0	1
Mu-type opioid receptor	0	1	0	1
Peroxisome proliferator-activated receptor delta	0	2	1	3
Glutamate receptor ionotropic, NMDA 1	0	0	1	1
Peroxisome proliferator-activated receptor alpha	0	2	1	3
ATP-binding cassette sub-family C member 8	0	1	0	1
Glutamate receptor ionotropic, NMDA 2A	0	0	1	1
Glutamate receptor ionotropic, NMDA 2B	0	0	1	1
ATP-sensitive inward rectifier potassium channel 11	0	1	0	1
Glutamate receptor ionotropic, NMDA 2C	0	0	1	1
Sodium/bile acid cotransporter	0	1	0	1
Thrombin	0	0	1	1
CDGSH iron-sulfur domain-containing protein 2	0	1	0	1
Glutamate receptor ionotropic, NMDA 3A	0	0	1	1
Neutral amino acid transporter A	0	1	0	1
Neutral amino acid transporter B(0)	0	1	0	1
Amino acid transporter	0	1	0	1
Nuclear receptor subfamily 1 group I member 2	0	0	3	3
Eukaryotic translation initiation factor 4E	0	0	1	1
Peptidyl-prolyl cis-trans isomerase FKBP1A	0	1	0	1
Peptidyl-prolyl cis-trans isomerase FKBP1A	0	4	2	6
Peptidyl-prolyl cis-trans isomerase FKBP1B	0	0	2	2
Peptidyl-prolyl cis-trans isomerase FKBP5	0	2	0	2
Programmed cell death protein 4	0	0	1	1
Serine/threonine-protein kinase mTOR	0	1	0	1
C-X-C chemokine receptor type 5 isoform 1	0	1	0	1
ubiquitin-conjugating enzyme E2 N	0	1	0	1
C-C chemokine receptor type 6	0	1	0	1
apelin receptor	0	1	0	1
streptokinase A precursor	0	0	1	1
Endoglycoceramidase II	0	0	0	1
Protein kinase C alpha type	0	1	0	1
Estrogen receptor	0	0	1	1
Protein kinase C delta type	0	1	0	1
Protein kinase C epsilon type	0	1	0	1
Protein kinase C zeta type	0	1	0	1
cAMP-dependent protein kinase catalytic subunit alpha	0	1	0	1
Protein kinase C gamma type	0	1	0	1
Protein kinase C beta type	0	1	0	1
Estrogen receptor beta	0	0	1	1
Protein kinase C eta type	0	1	0	1
Sphingosine kinase 2	0	1	0	1
Sphingosine kinase 1	0	1	0	1
Protein kinase C theta type	0	1	0	1
Sphingosine 1-phosphate receptor 2	0	1	1	2
Sphingosine 1-phosphate receptor 4	0	1	1	2
Sphingosine 1-phosphate receptor 1	0	1	1	2
Sodium-dependent serotonin transporter	0	1	1	2
Sphingosine 1-phosphate receptor 3	0	1	1	2
Sphingosine 1-phosphate receptor 5	0	1	1	2
Chain A, Ribosomal protein S6 kinase alpha-1	0	1	0	1
Chain X, Tyrosine-protein kinase Lyn	0	1	0	1
Chain A, Dual specificity protein kinase TTK	0	0	1	1
Chain A, Dual specificity protein kinase TTK	0	0	1	1
Transcription regulator protein BACH1	0	1	0	1
Transcription factor MafK	0	1	0	1
Macrophage migration inhibitory factor	0	1	0	1
NAD	0	0	0	1
Quinone oxidoreductase	0	0	0	3
Nuclear factor erythroid 2-related factor 2	0	0	0	1
Kelch-like ECH-associated protein 1	0	0	0	1
UDP-glucuronosyltransferase 2B7	0	0	0	2
UDP-glucuronosyltransferase 1A4	0	0	0	1
Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform	0	1	0	1
Corticotropin releasing hormone receptor 2	0	1	0	1
Lysine-specific demethylase 6B	0	1	0	1
Lysine-specific demethylase 4B	0	1	0	1
Cholesteryl ester transfer protein	0	0	1	1
Lysine-specific demethylase 5A	0	1	0	1
Endoplasmin	0	1	1	2
Heat shock protein 75 kDa, mitochondrial	0	1	0	1
Heat-shock protein	0	1	0	1
Putative heat shock protein HSP 90-alpha A4	0	1	0	1
Lysine-specific demethylase 4C	0	1	0	1
Beta-1 adrenergic receptor	0	1	0	1
Ras guanyl-releasing protein 3	0	0	1	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4A	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4C	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4D	0	1	0	1
Caspase-1	0	1	0	1
Chain A, Nuclear Receptor ROR-beta	0	1	0	1
Ornithine decarboxylase	0	0	0	1
Retinoic acid receptor alpha	0	2	2	7
Retinoic acid receptor alpha	0	1	2	3
Retinoic acid receptor gamma	0	2	2	7
Alpha-1A adrenergic receptor	0	1	0	1
Retinoic acid receptor gamma	0	1	2	3
Retinoic acid receptor beta	0	1	2	3
Cellular retinoic acid-binding protein 2	0	0	1	1
Retinoic acid receptor RXR-alpha	0	1	2	3
Retinoic acid receptor RXR-beta	0	2	2	4
Retinoic acid receptor RXR-beta	0	1	2	3
Retinoic acid receptor RXR-gamma	0	1	2	3
Indoleamine 2,3-dioxygenase 1	0	1	0	1
Nuclear receptor ROR-alpha	0	1	0	1
Cellular retinoic acid-binding protein 1	0	1	0	2
5-hydroxytryptamine receptor 2B	0	2	0	2
Retinoic acid receptor RXR-gamma	0	2	2	4
Cellular retinoic acid-binding protein 1	0	0	1	1
Indoleamine 2,3-dioxygenase 2	0	1	0	1
Nuclear receptor ROR-beta	0	1	0	1
Proteinase-activated receptor 2	0	1	0	1
Chain A, CHORISMATE MUTASE	0	1	0	1
Chain A, TYROSYL-tRNA SYNTHETASE	0	0	1	1
Plasma kallikrein	0	0	0	1
Carbonic anhydrase	0	0	0	1
Carbonic anhydrase	0	0	0	1
Large neutral amino acids transporter small subunit 1	0	1	0	1
SLC16A10 protein	0	0	0	1
Carbonic anhydrase	0	0	0	1
Carbonic anhydrase-like protein, putative	0	0	0	1
Carbonic anhydrase	0	0	0	1
Carbonic anhydrase	0	0	0	1
Carbonic anhydrase	0	0	0	1
Tubulin--tyrosine ligase	0	1	0	1
Monocarboxylate transporter 10	0	0	0	1
Taste receptor type 2 member 14	0	0	0	1
Chain A, Histone deacetylase-like amidohydrolase	0	1	0	1
Chain A, Histone deacetylase-like amidohydrolase	0	1	0	1
PAX8	0	0	0	1
cystic fibrosis transmembrane conductance regulator ATP-binding cassette sub-family C member 7	0	0	0	1
Histone deacetylase	0	1	0	1
Lysine-specific demethylase 4E	0	1	0	1
Gli1	0	1	0	1
nuclear receptor subfamily 0 group B member 1	0	1	0	1
cystic fibrosis transmembrane conductance regulator	0	1	0	1
steroidogenic factor 1	0	1	0	1
protein Wnt-3a precursor	0	1	0	1
DNA dC->dU-editing enzyme APOBEC-3F isoform a	1	0	0	1
Histone deacetylase 1	0	2	0	2
Nuclear receptor corepressor 1	0	2	0	2
Tubulin alpha-1A chain	0	1	0	1
Tubulin beta chain	0	1	0	1
Protein Tat	0	0	1	1
Aminopeptidase N	0	1	0	1
Cannabinoid receptor 1	0	1	0	1
Leukotriene A-4 hydrolase	0	1	0	1
Apoptosis regulator BAX	0	0	1	1
Platelet-activating factor acetylhydrolase	0	1	0	1
Histone deacetylase 1	0	1	0	1
Histone deacetylase	0	1	0	1
Renin	0	1	0	1
Histone deacetylase 3	0	1	0	1
Histone deacetylase	0	1	0	1
HD2 type histone deacetylase HDA106	0	2	0	2
Carboxypeptidase B2	0	1	0	1
Histone-lysine N-methyltransferase EHMT2	0	1	0	1
Histone deacetylase 7	0	1	0	1
Histone deacetylase 6	0	1	0	1
Histone deacetylase 4	0	1	0	1
REST corepressor 3	0	1	0	1
Nuclear receptor subfamily 1 group I member 2	0	0	1	1
Histone deacetylase 6	0	1	0	1
Histone deacetylase	0	1	0	1
serine/threonine-protein kinase PLK1	1	0	0	1
Ectonucleoside triphosphate diphosphohydrolase 1	0	0	0	1
DNA polymerase beta	0	1	0	1
Thymidine kinase, cytosolic	0	0	0	1
Thymidylate kinase	0	1	0	1
Thymidine kinase	0	1	0	2
Thymidine kinase	0	1	0	2
Butyrophilin subfamily 3 member A1	0	0	1	2
Geranylgeranyl pyrophosphate synthase	0	2	0	3
Farnesyl pyrophosphate synthase	0	2	0	2
Neutrophil collagenase	0	1	0	1
Farnesyl diphosphate synthase	0	1	0	1
Farnesyl pyrophosphate synthase	0	2	0	2
Geranylgeranyl pyrophosphate synthase	0	2	0	2
Farnesyl pyrophosphate synthase	0	1	0	1
H	0	1	0	1
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Synonyms(2)

Research Excerpts

Overview

Context

Treatment

Research

Studies (141)

Protein Targets (1,856)

Lymphoma, Primary Effusion

Synonyms(2)

Research Excerpts

Overview

Context

Treatment

Research

Studies (141)

Drugs Studied (153)

Protein Targets (1,856)