Page last updated: 2024-12-10

2,4-dinitrofluorobenzene sulfonic acid

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Cross-References

ID SourceID
PubMed CID3035215
MeSH IDM0131834

Synonyms (7)

Synonym
2,4-dinitrofluorobenzene sulfonic acid
fluoro 2,4-dinitrobenzenesulfonate
143134-35-4
benzenesulfonic acid, fluoro-2,4-dinitro-
DTXSID30931757
1-[(fluorooxy)sulfonyl]-2,4-dinitrobenzene
benzenesulfonic acid,fluoro-2,4-dinitro-(9ci)

Research Excerpts

Bioavailability

ExcerptReferenceRelevance
"5-fold higher than in wild-type mice, suggesting increased bioavailability of SP."( Neutral endopeptidase (EC 3.4.24.11) terminates colitis by degrading substance P.
Barbara, G; Bunnett, NW; Collins, SM; Figini, M; Geppetti, P; Gerard, C; Gerard, N; Grady, EF; Qiu, B; Sturiale, S, 1999
)
0.3

Dosage Studied

ExcerptRelevanceReference
"Skin blood flow in allergic contact reactions and cross-sensitivity were evaluated using laser Doppler flowmetry (LDF) to study the dose-response relationships in phases of induction and challenge in guinea pigs."( Evaluation of contact allergy to chemicals using laser Doppler flowmetry (LDF) technique.
Aoyama, K; Li, Q; Matsushita, T, 1992
)
0.28
" Rats were given zinc at a dosage of 2 or 30 mg/kg body wt or glucose by gavage starting 3 days before colitis was induced through the intrarectal administration of dinitro-benzene-sulfonic acid and for 7 days thereafter."( Effect of zinc supplementation on intestinal permeability in experimental colitis.
Barollo, M; D'inca, R; Di Leo, V; Fries, W; Mazzon, E; Sturniolo, GC, 2002
)
0.31
" Dose-response analyses were performed with dinitrobenzene sulfonic acid (DNBS) and formaldehyde formulated either in water, 1% L92, dimethyl sulfoxide (DMSO) or dimethyl formamide (DMF)."( Examination of a vehicle for use with water soluble materials in the murine local lymph node assay.
Cruse, LW; Dearman, RJ; Gerberick, GF; Kimber, I; Ryan, CA; Skinner, RA, 2002
)
0.31
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (112)

TimeframeStudies, This Drug (%)All Drugs %
pre-19903 (2.68)18.7374
1990's12 (10.71)18.2507
2000's35 (31.25)29.6817
2010's43 (38.39)24.3611
2020's19 (16.96)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 10.49

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index10.49 (24.57)
Research Supply Index4.75 (2.92)
Research Growth Index5.25 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (10.49)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews1 (0.87%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other114 (99.13%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]