Compounds > 4-nitroacetophenone
Page last updated: 2024-09-21

4-nitroacetophenone

Description

4-nitroacetophenone : A member of the class of acetophenones that is acetophenone substituted at the para-position by a nitro group. [Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Cross-References

ID SourceID
PubMed CID7487
CHEMBL ID167997
CHEBI ID60546
CHEBI ID28735
SCHEMBL ID11922684
SCHEMBL ID27765
MeSH IDM0042398

Synonyms (79)

Synonym
MLS002152933
smr001224529
p-nitrophenyl methyl ketone
paranitroacetophenone
p-acetylnitrobenzene
ethanone, 1-(4-nitrophenyl)-
nsc41590
acetophenone, 4'-nitro-
nsc-41590
4'-nitroacetophenone
NCGC00091379-01
pnap
ccris 1676
nsc 41590
einecs 202-827-4
methyl-p-nitrophenyl ketone
ai3-19032
4-nitroacetophenone
C02803
p-nitroacetophenone
100-19-6
4'-nitroacetophenone, 98%
1-(4-nitrophenyl)ethanone
STK328124
AC-10991
CHEBI:60546 ,
p-nitrobenzoyl
4-(nitrophenyl)carbonyl
p-(nitrophenyl)carbonyl
CHEMBL167997
chebi:28735 ,
N0111
AKOS000118933
NCGC00091379-02
unii-4fm2j8hq27
4fm2j8hq27 ,
HMS3039I06
dtxcid105724
tox21_200265
cas-100-19-6
NCGC00257819-01
dtxsid1025724 ,
SCHEMBL11922684
1-(4-nitrophenyl)-ethanone
BBL010615
1-acetyl-4-nitrobenzene
FT-0689209
BP-13008
PS-4614
EPITOPE ID:138720
4-nitrophenylacetoaldehyde
4-acetylnitrobenzene
1-(4-nitrophenyl)ethan-1-one
AH-214/02411035
SCHEMBL27765
p-nitro-acetophenone
4-nitrophenyl methyl ketone
4nitro acetophenone
p-nitro acetophenone
4-nitro acetophenone
1-(4-nitro-phenyl)ethanone
1-(4-nitrophenyl)ethanone #
methyl 4-nitrophenyl ketone
CS-W020570
W-108972
nsc 41590; p-acetylnitrobenzene
F0001-0011
mfcd00007355
AC1233
para-nitroacetophenone
SY011156
4 inverted exclamation mark -nitroacetophenone
nitroacetophenone, p-
methyl p-nitrophenyl ketone
acetophenone, p-nitro-
1-(4-nitro-phenyl)-ethanone
Q27103872
EN300-19195
A936889

Drug Classes (2)

ClassDescription
acetophenonesA class or aromatic ketone consisting of acetophenone, PhC(=O)CH3, and its substituted derivatives.
C-nitro compoundA nitro compound having the nitro group (-NO2) attached to a carbon atom.
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Protein Targets (11)

Potency Measurements

ProteinTaxonomyMeasurementAverage (µ)Min (ref.)Avg (ref.)Max (ref.)Bioassay(s)
interleukin 8Homo sapiens (human)Potency74.97800.047349.480674.9780AID651758
AR proteinHomo sapiens (human)Potency44.66840.000221.22318,912.5098AID588516
pregnane X nuclear receptorHomo sapiens (human)Potency54.53810.005428.02631,258.9301AID1346982
estrogen nuclear receptor alphaHomo sapiens (human)Potency24.45820.000229.305416,493.5996AID1259244; AID743075
activating transcription factor 6Homo sapiens (human)Potency61.72020.143427.612159.8106AID1159516
mitogen-activated protein kinase 1Homo sapiens (human)Potency50.11870.039816.784239.8107AID995
nuclear factor erythroid 2-related factor 2 isoform 1Homo sapiens (human)Potency74.97800.000627.21521,122.0200AID651741
gemininHomo sapiens (human)Potency23.10930.004611.374133.4983AID624296
Voltage-dependent calcium channel gamma-2 subunitMus musculus (house mouse)Potency48.60710.001557.789015,848.9004AID1259244
Glutamate receptor 2Rattus norvegicus (Norway rat)Potency48.60710.001551.739315,848.9004AID1259244
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Other Measurements

ProteinTaxonomyMeasurementAverageMin (ref.)Avg (ref.)Max (ref.)Bioassay(s)
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Ceullar Components (1)

Processvia Protein(s)Taxonomy
plasma membraneGlutamate receptor 2Rattus norvegicus (Norway rat)
[Information is prepared from geneontology information from the June-17-2024 release]

Bioassays (18)

Assay IDTitleYearJournalArticle
AID588501High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Lethal Factor Protease, MLPCN compound set2010Current protocols in cytometry, Oct, Volume: Chapter 13Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening.
AID588501High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Lethal Factor Protease, MLPCN compound set2006Cytometry. Part A : the journal of the International Society for Analytical Cytology, May, Volume: 69, Issue:5
Microsphere-based protease assays and screening application for lethal factor and factor Xa.
AID588501High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Lethal Factor Protease, MLPCN compound set2010Assay and drug development technologies, Feb, Volume: 8, Issue:1
High-throughput multiplex flow cytometry screening for botulinum neurotoxin type a light chain protease inhibitors.
AID504810Antagonists of the Thyroid Stimulating Hormone Receptor: HTS campaign2010Endocrinology, Jul, Volume: 151, Issue:7
A small molecule inverse agonist for the human thyroid-stimulating hormone receptor.
AID588497High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, MLPCN compound set2010Current protocols in cytometry, Oct, Volume: Chapter 13Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening.
AID588497High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, MLPCN compound set2006Cytometry. Part A : the journal of the International Society for Analytical Cytology, May, Volume: 69, Issue:5
Microsphere-based protease assays and screening application for lethal factor and factor Xa.
AID588497High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, MLPCN compound set2010Assay and drug development technologies, Feb, Volume: 8, Issue:1
High-throughput multiplex flow cytometry screening for botulinum neurotoxin type a light chain protease inhibitors.
AID1745845Primary qHTS for Inhibitors of ATXN expression
AID588499High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain A protease, MLPCN compound set2010Current protocols in cytometry, Oct, Volume: Chapter 13Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening.
AID588499High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain A protease, MLPCN compound set2006Cytometry. Part A : the journal of the International Society for Analytical Cytology, May, Volume: 69, Issue:5
Microsphere-based protease assays and screening application for lethal factor and factor Xa.
AID588499High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain A protease, MLPCN compound set2010Assay and drug development technologies, Feb, Volume: 8, Issue:1
High-throughput multiplex flow cytometry screening for botulinum neurotoxin type a light chain protease inhibitors.
AID504812Inverse Agonists of the Thyroid Stimulating Hormone Receptor: HTS campaign2010Endocrinology, Jul, Volume: 151, Issue:7
A small molecule inverse agonist for the human thyroid-stimulating hormone receptor.
AID651635Viability Counterscreen for Primary qHTS for Inhibitors of ATXN expression
AID200690Mutagenic activity in an Ames test on Salmonella Typhimurium TA98; Activity is log of revertants/nmol1991Journal of medicinal chemistry, Feb, Volume: 34, Issue:2
Structure-activity relationship of mutagenic aromatic and heteroaromatic nitro compounds. Correlation with molecular orbital energies and hydrophobicity.
AID323693Activity of rat liver 3-alpha-HSD assessed as formation of corresponding (S)-alcohol products per mg of protein2008Bioorganic & medicinal chemistry, Feb-01, Volume: 16, Issue:3
Electronic effects of para-substitution on acetophenones in the reaction of rat liver 3alpha-hydroxysteroid dehydrogenase.
AID323691Activity of rat liver 3-alpha-HSD assessed as formation of corresponding (S)-alcohol products2008Bioorganic & medicinal chemistry, Feb-01, Volume: 16, Issue:3
Electronic effects of para-substitution on acetophenones in the reaction of rat liver 3alpha-hydroxysteroid dehydrogenase.
AID23442Partition coefficient (logP)1991Journal of medicinal chemistry, Feb, Volume: 34, Issue:2
Structure-activity relationship of mutagenic aromatic and heteroaromatic nitro compounds. Correlation with molecular orbital energies and hydrophobicity.
AID323692Ratio of Vmax to Km for rat liver 3-alpha-HSD for formation of corresponding (S)-alcohol products2008Bioorganic & medicinal chemistry, Feb-01, Volume: 16, Issue:3
Electronic effects of para-substitution on acetophenones in the reaction of rat liver 3alpha-hydroxysteroid dehydrogenase.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (37)

TimeframeStudies, This Drug (%)All Drugs %
pre-199017 (45.95)18.7374
1990's8 (21.62)18.2507
2000's3 (8.11)29.6817
2010's7 (18.92)24.3611
2020's2 (5.41)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews2 (5.26%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other36 (94.74%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceDescriptionRelationhip StrengthStudiesTrialsClassesRoles
dinitrochlorobenzene[no description available]medium10C-nitro compound;
monochlorobenzenes		allergen;
epitope;
sensitiser
4-nitrobenzaldehyde[no description available]medium40benzaldehydes;
C-nitro compound
7-nitroindazole[no description available]medium10
metronidazole[no description available]medium50C-nitro compound;
imidazoles;
primary alcohol		antiamoebic agent;
antibacterial drug;
antimicrobial agent;
antiparasitic agent;
antitrichomonal drug;
environmental contaminant;
prodrug;
radiosensitizing agent;
xenobiotic
niridazole[no description available]medium101,3-thiazoles;
C-nitro compound
dinitrofluorobenzene[no description available]medium10C-nitro compound;
organofluorine compound		agrochemical;
allergen;
chromatographic reagent;
EC 2.7.3.2 (creatine kinase) inhibitor;
protein-sequencing agent;
spectrophotometric reagent
1-nitronaphthalene[no description available]medium10mononitronaphthaleneenvironmental contaminant;
mouse metabolite
1-chloro-2-nitrobenzene[no description available]medium10C-nitro compound;
monochlorobenzenes
2,5-dichloronitrobenzene[no description available]medium10
2-nitroanisole[no description available]medium102-nitroanisolescarcinogenic agent
4-nitrobiphenyl[no description available]medium10biphenyls
2,4-dinitroaniline[no description available]medium10nitroaniline
nitrobenzene[no description available]medium10nitroarene;
nitrobenzenes
1,2-dichloro-4-nitrobenzene[no description available]medium10
3-dinitrobenzene[no description available]medium10dinitrobenzeneneurotoxin
4-chloronitrobenzene[no description available]medium10C-nitro compound
4-nitroanisole[no description available]medium104-nitroanisoles
1,4-dinitrobenzene[no description available]medium10dinitrobenzene
2,4-dinitroanisole[no description available]medium10dinitroanisolesexplosive
2,4,7-trinitrofluorenone[no description available]medium10
1,2-dinitrobenzene[no description available]medium10dinitrobenzene
2-nitrobenzaldehyde[no description available]medium10benzaldehydes;
C-nitro compound
2-nitronaphthalene[no description available]medium10mononitronaphthalene
9-nitroanthracene[no description available]medium10anthracenes
5-nitroacenaphthene[no description available]medium10nitronaphthalene
erythropoietin[no description available]medium10dinitronaphthalenegenotoxin
1,3-dinitronaphthalene[no description available]medium10dinitronaphthalene
5-nitroquinoline[no description available]medium10
2-nitrofluorene[no description available]medium10nitroarenecarcinogenic agent;
mutagen
2,4-dichloro-1-nitrobenzene[no description available]medium10
5-nitro-2-furaldehyde[no description available]medium10C-nitro compound;
furans
2-nitropyrene[no description available]medium10pyrenes
3-nitrofluoranthene[no description available]medium10nitronaphthalene
2-amino-7-nitrofluorene[no description available]medium10
2-bromo-4,6-dinitroaniline[no description available]medium10
5-nitroindazole[no description available]medium10
2,7-dinitrofluorene[no description available]medium10
1-nitropyrene[no description available]medium10nitroarenecarcinogenic agent
nsc 520594[no description available]medium10
2-hydroxy-7-nitrofluorene[no description available]medium10
6-nitrochrysene[no description available]medium10carbopolycyclic compound
6-nitroindazole[no description available]medium10
2-nitrofluoranthene[no description available]medium10
7-nitrobenzanthracene[no description available]medium10phenanthrenes
3,9-dinitrofluoranthene[no description available]medium10nitronaphthalene
2,7-dinitrofluorenone[no description available]medium10
1,6-dinitropyrene[no description available]medium10pyrenes
1,8-dinitropyrene[no description available]medium10pyrenes
6-nitrobenzo(a)pyrene[no description available]medium10ortho- and peri-fused polycyclic arene
1-nitrobenzo(a)pyrene[no description available]medium10
3-nitrobenzo(a)pyrene[no description available]medium10
1,3-dinitropyrene[no description available]medium10pyrenes
3,7-dinitrofluoranthene[no description available]medium10nitronaphthalene
4-nitropyrene[no description available]medium10pyrenes
3-nitroperylene[no description available]medium10phenanthrenes
1-nitro-2,4-difluorobenzene[no description available]medium10
5-nitroisoquinoline[no description available]medium10
9-nitrophenanthrene[no description available]medium10
5-nitro-1,10-phenanthroline[no description available]medium10
1-fluoro-2-nitrobenzene[no description available]medium10
2-nitrobenzimidazole[no description available]medium10
2,4-dinitrophenylhydrazine[no description available]medium10C-nitro compound;
phenylhydrazines		reagent
2-nitro-4-phenylenediamine[no description available]medium10C-nitro compound;
primary amino compound
5-Nitroisatin[no description available]medium10indolesanticoronaviral agent
2-amino-5-nitrophenol[no description available]medium103-nitrophenols
1,2-diamino-4-nitrobenzene[no description available]medium10C-nitro compound;
primary amino compound
furazolidone[no description available]medium10
nitrofurazone[no description available]medium50
nitrofurantoin[no description available]medium10imidazolidine-2,4-dione;
nitrofuran antibiotic;
organonitrogen heterocyclic antibiotic;
organooxygen heterocyclic antibiotic		antibacterial drug;
antiinfective agent;
hepatotoxic agent
acetophenone[no description available]medium20acetophenonesanimal metabolite;
photosensitizing agent;
xenobiotic
4-bromoacetophenone[no description available]medium10
4-acetylanisole[no description available]medium10acetophenones;
monomethoxybenzene
camphor, (+-)-isomer[no description available]medium10bornane monoterpenoid;
cyclic monoterpene ketone		plant metabolite
heme[no description available]medium10
nad[no description available]medium20organophosphate oxoanioncofactor;
human metabolite;
hydrogen acceptor;
Saccharomyces cerevisiae metabolite
methylphenyl carbinol[no description available]medium10aromatic alcoholmouse metabolite
goethite[no description available]medium10
5-chloromethylfluorescein diacetate[no description available]medium10acetate esterfluorochrome
mercaptoethanol[no description available]medium20alkanethiol;
primary alcohol		geroprotector
s-(4-nitrophenacyl)glutathione[no description available]medium10
erythrosine[no description available]medium10
phenyl acetate[no description available]medium10benzenes;
phenyl acetates
deuterium[no description available]medium10dihydrogen
chloramphenicol[no description available]medium10C-nitro compound;
carboxamide;
diol;
organochlorine compound		antibacterial drug;
antimicrobial agent;
Escherichia coli metabolite;
geroprotector;
Mycoplasma genitalium metabolite;
protein synthesis inhibitor
beta-aminoethyl isothiourea[no description available]medium10
tiopronin[no description available]medium10N-acyl-amino acid
ethidium[no description available]medium10phenanthridinesfluorochrome;
intercalator
ditiocarb[no description available]medium10dithiocarbamic acidschelator;
copper chelator
fluorouracil[no description available]medium10nucleobase analogue;
organofluorine compound		antimetabolite;
antineoplastic agent;
environmental contaminant;
immunosuppressive agent;
radiosensitizing agent;
xenobiotic
cysteine[no description available]medium10cysteiniumfundamental metabolite
cytarabine[no description available]medium10beta-D-arabinoside;
monosaccharide derivative;
pyrimidine nucleoside		antimetabolite;
antineoplastic agent;
antiviral agent;
immunosuppressive agent
ethylmaleimide[no description available]medium10maleimidesanticoronaviral agent;
EC 1.3.1.8 [acyl-CoA dehydrogenase (NADP(+))] inhibitor;
EC 2.1.1.122 [(S)-tetrahydroprotoberberine N-methyltransferase] inhibitor;
EC 2.7.1.1 (hexokinase) inhibitor
cysteamine[no description available]medium10amine;
thiol		geroprotector;
human metabolite;
mouse metabolite;
radiation protective agent
1-methyl-2-nitroimidazole[no description available]medium10
misonidazole[no description available]medium70
azomycin[no description available]medium60C-nitro compound;
imidazoles		antitubercular agent
etanidazole[no description available]medium10C-nitro compound;
imidazoles;
monocarboxylic acid amide		alkylating agent;
antineoplastic agent;
prodrug;
radiosensitizing agent
hydroxyl radical[no description available]medium30oxygen hydride;
oxygen radical;
reactive oxygen species
1-butanol[no description available]medium10alkyl alcohol;
primary alcohol;
short-chain primary fatty alcohol		human metabolite;
mouse metabolite;
protic solvent
triacetoneamine-n-oxyl[no description available]medium10aminoxyls;
piperidones		radical scavenger
allopurinol[no description available]medium10nucleobase analogue;
organic heterobicyclic compound		antimetabolite;
EC 1.17.3.2 (xanthine oxidase) inhibitor;
gout suppressant;
radical scavenger
5-phenoxysulfonyl-1-methyl-4-nitroimidazole[no description available]medium10
norpseudopelleterine-n-oxyl[no description available]medium20
hypoxanthine[no description available]medium10nucleobase analogue;
oxopurine;
purine nucleobase		fundamental metabolite
hydrogen[no description available]medium10elemental hydrogen;
elemental molecule;
gas molecular entity		antioxidant;
electron donor;
food packaging gas;
fuel;
human metabolite
inosine[no description available]medium10inosines;
purines D-ribonucleoside		Escherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
nadp[no description available]medium20
singlet oxygen[no description available]medium10chalcogen;
monoatomic oxygen;
nonmetal atom		macronutrient
tempo[no description available]medium10aminoxyls;
piperidines		catalyst;
ferroptosis inhibitor;
radical scavenger
guanosine[no description available]medium10guanosines;
purines D-ribonucleoside		fundamental metabolite
prostaglandin d2[no description available]medium10prostaglandins Dhuman metabolite;
mouse metabolite
vitamin k semiquinone radical[no description available]medium10
dinoprost[no description available]medium20monocarboxylic acid;
prostaglandins Falpha		human metabolite;
mouse metabolite
4-benzoylpyridine[no description available]medium10aromatic ketone
dimethyl fumarate[no description available]medium10diester;
enoate ester;
methyl ester		antipsoriatic;
immunomodulator
fumarates[no description available]medium10butenedioate;
C4-dicarboxylate		human metabolite;
metabolite;
Saccharomyces cerevisiae metabolite
nitrous oxide[no description available]medium10gas molecular entity;
nitrogen oxide		analgesic;
bacterial metabolite;
food packaging gas;
food propellant;
general anaesthetic;
greenhouse gas;
inhalation anaesthetic;
NMDA receptor antagonist;
raising agent;
refrigerant;
vasodilator agent
dithiothreitol[no description available]medium101,4-dimercaptobutane-2,3-diol;
butanediols;
dithiol;
glycol;
thiol		chelator;
human metabolite;
reducing agent
acetohexamide[no description available]low00acetophenones;
N-sulfonylurea		hypoglycemic agent;
insulin secretagogue
acetovanillone[no description available]low00acetophenones;
aromatic ketone;
methyl ketone		antirheumatic drug;
EC 1.6.3.1. [NAD(P)H oxidase (H2O2-forming)] inhibitor;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug;
peripheral nervous system drug;
plant metabolite
ly 171883[no description available]low00acetophenones;
aromatic ether;
phenols;
tetrazoles		anti-asthmatic drug;
leukotriene antagonist
phenacyl bromide[no description available]low00acetophenones;
alpha-bromoketone		metabolite
4-hydroxypropiophenone[no description available]low00acetophenones
3,4-dihydroxyacetophenone[no description available]low00acetophenones;
catechols;
dihydroxyacetophenone		metabolite
acetosyringone[no description available]low00acetophenones;
dimethoxybenzene;
phenols		anti-asthmatic drug;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug;
peripheral nervous system drug;
plant metabolite
u 0521[no description available]low00acetophenones
acrovestone[no description available]low00acetophenones;
aromatic ether;
olefinic compound;
polyphenol		antioxidant;
EC 1.14.18.1 (tyrosinase) inhibitor;
plant metabolite
(R)-Bitalin A[no description available]low00acetophenones
levoplast[no description available]low00C-nitro compound
parathion[no description available]low00C-nitro compound;
organic thiophosphate;
organothiophosphate insecticide		acaricide;
agrochemical;
avicide;
EC 3.1.1.7 (acetylcholinesterase) inhibitor;
EC 3.1.1.8 (cholinesterase) inhibitor;
mouse metabolite
3-nitropropionic acid[no description available]low00C-nitro compoundantimycobacterial drug;
EC 1.3.5.1 [succinate dehydrogenase (quinone)] inhibitor;
mycotoxin;
neurotoxin
aristolochic acid i[no description available]low00aristolochic acids;
aromatic ether;
C-nitro compound;
cyclic acetal;
monocarboxylic acid;
organic heterotetracyclic compound		carcinogenic agent;
metabolite;
mutagen;
nephrotoxin;
toxin
azathioprine[no description available]low00aryl sulfide;
C-nitro compound;
imidazoles;
thiopurine		antimetabolite;
antineoplastic agent;
carcinogenic agent;
DNA synthesis inhibitor;
hepatotoxic agent;
immunosuppressive agent;
prodrug
bay-k-8644[no description available]low00(trifluoromethyl)benzenes;
C-nitro compound;
dihydropyridine;
methyl ester
benefin[no description available]low00C-nitro compound;
organofluorine compound;
substituted aniline;
tertiary amino compound		agrochemical;
herbicide
dimetridazole[no description available]low00C-nitro compound;
imidazoles		antiparasitic agent;
antiprotozoal drug
flunitrazepam[no description available]low001,4-benzodiazepinone;
C-nitro compound;
monofluorobenzenes		anxiolytic drug;
GABAA receptor agonist;
sedative
methyl parathion[no description available]low00C-nitro compound;
organic thiophosphate;
organothiophosphate insecticide		acaricide;
agrochemical;
antifungal agent;
EC 3.1.1.7 (acetylcholinesterase) inhibitor;
EC 3.1.1.8 (cholinesterase) inhibitor;
environmental contaminant;
genotoxin
nicardipine[no description available]low00benzenes;
C-nitro compound;
diester;
dihydropyridine;
methyl ester;
tertiary amino compound
niclosamide[no description available]low00benzamides;
C-nitro compound;
monochlorobenzenes;
salicylanilides;
secondary carboxamide		anthelminthic drug;
anticoronaviral agent;
antiparasitic agent;
apoptosis inducer;
molluscicide;
piscicide;
STAT3 inhibitor
nifedipine[no description available]low00C-nitro compound;
dihydropyridine;
methyl ester		calcium channel blocker;
human metabolite;
tocolytic agent;
vasodilator agent
nilutamide[no description available]low00(trifluoromethyl)benzenes;
C-nitro compound;
imidazolidinone		androgen antagonist;
antineoplastic agent
nimesulide[no description available]low00aromatic ether;
C-nitro compound;
sulfonamide		cyclooxygenase 2 inhibitor;
non-steroidal anti-inflammatory drug
nimetazepam[no description available]low001,4-benzodiazepinone;
C-nitro compound		anticonvulsant;
antispasmodic drug;
GABA modulator;
sedative
nimodipine[no description available]low002-methoxyethyl ester;
C-nitro compound;
dicarboxylic acids and O-substituted derivatives;
diester;
dihydropyridine;
isopropyl ester		antihypertensive agent;
calcium channel blocker;
cardiovascular drug;
vasodilator agent
nisoldipine[no description available]low00C-nitro compound;
dicarboxylic acids and O-substituted derivatives;
diester;
dihydropyridine;
methyl ester
nitrazepam[no description available]low001,4-benzodiazepinone;
C-nitro compound		anticonvulsant;
antispasmodic drug;
drug metabolite;
GABA modulator;
sedative
nitrendipine[no description available]low00C-nitro compound;
dicarboxylic acids and O-substituted derivatives;
diester;
dihydropyridine;
ethyl ester;
methyl ester		antihypertensive agent;
calcium channel blocker;
geroprotector;
vasodilator agent
nizatidine[no description available]low001,3-thiazoles;
C-nitro compound;
carboxamidine;
organic sulfide;
tertiary amino compound		anti-ulcer drug;
cholinergic drug;
H2-receptor antagonist
n-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide[no description available]low00aromatic ether;
C-nitro compound;
sulfonamide		antineoplastic agent;
cyclooxygenase 2 inhibitor
oxamniquine[no description available]low00aromatic primary alcohol;
C-nitro compound;
quinolines;
secondary amino compound
4-nitrophenylacetic acid[no description available]low00C-nitro compound;
phenylacetic acids
ronidazole[no description available]low00C-nitro compound;
carbamate ester;
imidazoles		antiparasitic agent;
antiprotozoal drug
trifluralin[no description available]low00(trifluoromethyl)benzenes;
C-nitro compound;
substituted aniline		agrochemical;
environmental contaminant;
herbicide;
xenobiotic
4-nitroquinoline-1-oxide[no description available]low00C-nitro compound;
quinoline N-oxide		carcinogenic agent
nifenalol[no description available]low00C-nitro compound
chloropicrin[no description available]low00C-nitro compound;
one-carbon compound;
organochlorine compound		antifungal agrochemical;
fumigant insecticide;
nematicide
quintozene[no description available]low00aromatic fungicide;
C-nitro compound;
pentachlorobenzenes		antifungal agrochemical
musk ambrette (artificial)[no description available]low00C-nitro compound
picryl chloride[no description available]low00C-nitro compound;
monochlorobenzenes		allergen;
epitope;
explosive;
hapten
picric acid[no description available]low00C-nitro compoundantiseptic drug;
explosive;
fixative
2,4-dinitrobenzenesulfonic acid[no description available]low00arenesulfonic acid;
C-nitro compound
2-nitro-4-methylaniline[no description available]low00C-nitro compound
3,5-dinitrobenzoic acid[no description available]low00benzoic acids;
C-nitro compound
5-nitro-2-toluidine[no description available]low00C-nitro compound
4-nitrobenzyl chloride[no description available]low00benzyl chlorides;
C-nitro compound		mutagen
tecnazene[no description available]low00aromatic fungicide;
C-nitro compound;
tetrachlorobenzene		antifungal agrochemical
4-amino-2-nitrotoluene[no description available]low00C-nitro compound
2-amino-5-nitrothiazole[no description available]low00C-nitro compound;
thiazoles
naphthol yellow[no description available]low00C-nitro compound;
naphthalenesulfonic acid;
naphthols		histological dye
trinitrobenzenesulfonic acid[no description available]low00arenesulfonic acid;
C-nitro compound		epitope;
explosive;
reagent
1-bromo-2,4-dinitrobenzene[no description available]low00C-nitro compound;
organobromine compound
3,5-dinitrosalicylic acid[no description available]low00C-nitro compound;
monohydroxybenzoic acid		hapten
3,5-dinitrotoluene[no description available]low00C-nitro compound
2-methyl-5-nitroimidazole[no description available]low00C-nitro compound;
imidazoles
4-nitrophenyl acetate[no description available]low00C-nitro compound;
phenyl acetates
methylparaoxon[no description available]low00C-nitro compound
dinobuton[no description available]low00C-nitro compound
pyrrolnitrin[no description available]low00alkaloid;
C-nitro compound;
monochlorobenzenes;
pyrroles		antifungal drug;
bacterial metabolite
dinoterb[no description available]low00C-nitro compound;
phenols
2,4-dinitrothiocyanatobenzene[no description available]low00C-nitro compound;
thiocyanates		hapten;
tolerogen
2,4,6-trichlorophenyl 4-nitrophenyl ether[no description available]low00aromatic ether;
C-nitro compound;
chlorobenzenes		EC 1.3.3.4 (protoporphyrinogen oxidase) inhibitor;
herbicide
n-methylamino-2-nitro-4-n',n'-bis(2-hydroxyethyl)aminobenzene[no description available]low00C-nitro compound
4-nitroimidazole[no description available]low00C-nitro compound;
imidazoles
2-(alpha-thenoylamino)-2-nitro-5-thiazole[no description available]low001,3-thiazoles;
C-nitro compound
nitroxoline[no description available]low00C-nitro compound;
monohydroxyquinoline		antifungal agent;
antiinfective agent;
antimicrobial agent;
renal agent
nitralin[no description available]low00C-nitro compound
1,2-epoxy-3-(p-nitrophenoxy)propane[no description available]low00aromatic ether;
C-nitro compound;
epoxide
nimorazole[no description available]low00C-nitro compound;
imidazoles
4-chloro-7-nitrobenzofurazan[no description available]low00benzoxadiazole;
C-nitro compound;
organochlorine compound		EC 1.4.3.4 (monoamine oxidase) inhibitor;
EC 3.6.1.3 (adenosinetriphosphatase) inhibitor;
fluorescent probe;
fluorochrome
ipronidazole[no description available]low00C-nitro compound;
imidazoles
ornidazole[no description available]low00C-nitro compound;
imidazoles;
organochlorine compound;
secondary alcohol		antiamoebic agent;
antibacterial drug;
antiinfective agent;
antiprotozoal drug;
antitrichomonal drug;
epitope
oryzalin[no description available]low00aromatic amine;
C-nitro compound;
sulfonamide;
tertiary amino compound		agrochemical;
antimitotic;
herbicide
fenitrothion[no description available]low00C-nitro compound;
organic thiophosphate		acaricide;
agrochemical;
EC 3.1.1.7 (acetylcholinesterase) inhibitor;
EC 3.1.1.8 (cholinesterase) inhibitor;
insecticide
benzonidazole[no description available]low00C-nitro compound;
imidazoles;
monocarboxylic acid amide		antiprotozoal drug
N-(3-methyl-1,1-dioxo-1,4-thiazinan-4-yl)-1-(5-nitro-2-furanyl)methanimine[no description available]low00C-nitro compound;
furans
3-nitro-1-propanol[no description available]low00C-nitro compound
amoscanate[no description available]low00C-nitro compound;
isothiocyanate;
secondary amino compound		schistosomicide drug
profluralin[no description available]low00C-nitro compound
dinitramine[no description available]low00C-nitro compound
hc blue no. 2[no description available]low00C-nitro compound
fluchloralin[no description available]low00C-nitro compound
butralin[no description available]low00C-nitro compound
isopropalin[no description available]low00C-nitro compound
pendimethalin[no description available]low00C-nitro compound;
secondary amino compound;
substituted aniline		agrochemical;
environmental contaminant;
herbicide
ethafluralin[no description available]low00C-nitro compound
acifluorfen[no description available]low00aromatic ether;
benzoic acids;
C-nitro compound;
monocarboxylic acid;
organochlorine compound;
organofluorine compound		agrochemical;
EC 1.3.3.4 (protoporphyrinogen oxidase) inhibitor;
herbicide
bromethalin[no description available]low00C-nitro compound
fomesafen[no description available]low00aromatic ether;
C-nitro compound;
monochlorobenzenes;
N-sulfonylcarboxamide;
organofluorine compound;
phenols		agrochemical;
EC 1.3.3.4 (protoporphyrinogen oxidase) inhibitor;
herbicide
bmy 25067[no description available]low00C-nitro compound;
organic disulfide		antineoplastic agent
2-Amino-5-(5-nitro-2-furyl)-1,3,4-thiadiazole[no description available]low00C-nitro compound;
furans
musk xylene[no description available]low00C-nitro compoundcarcinogenic agent;
explosive;
fragrance
4-nitrophenylalanine[no description available]low00C-nitro compound
4-nitrobenzyl bromide[no description available]low00benzyl bromides;
C-nitro compound		allergen;
sensitiser
nitarsone[no description available]low00C-nitro compound;
organoarsonic acid		agrochemical;
antiprotozoal drug
5'-nitro-2'-propoxyacetanilide[no description available]low00aromatic ether;
C-nitro compound
cinitapride[no description available]low00aromatic ether;
C-nitro compound
5-nitrouracil[no description available]low00C-nitro compound
3-nitrobenzyl alcohol[no description available]low00C-nitro compound
4-nitrobenzyl alcohol[no description available]low00benzyl alcohols;
C-nitro compound		xenobiotic metabolite
secnidazole[no description available]low00C-nitro compound;
imidazoles;
secondary alcohol		epitope
4-nitrophenyl palmitate[no description available]low00C-nitro compound;
hexadecanoate ester
4-nitrophenyl butyrate[no description available]low00butyrate ester;
C-nitro compound
2-nitrophenylacetic acid[no description available]low00C-nitro compound;
phenylacetic acids
4-nitrophenyl sulfate[no description available]low00aryl sulfate;
C-nitro compound		human metabolite
4-nitrophenyl-alpha-l-fucoside[no description available]low00alpha-L-fucoside;
C-nitro compound		chromogenic compound
4-nitrophenylglucuronide[no description available]low00beta-D-glucosiduronic acid;
C-nitro compound		chromogenic compound
chloramphenicol stearate[no description available]low00C-nitro compound
4,5-dimethoxy-2-nitrobenzaldehyde[no description available]low00aromatic ether;
C-nitro compound
4-nitrophenyl beta-d-xyloside[no description available]low00C-nitro compound;
xyloside		chromogenic compound
fluazinam[no description available]low00(trifluoromethyl)benzenes;
aminopyridine;
C-nitro compound;
chloropyridine;
monochlorobenzenes;
secondary amino compound		allergen;
antifungal agrochemical;
apoptosis inducer;
environmental contaminant;
xenobiotic
2-nitropropanol[no description available]low00C-nitro compound
aclonifen[no description available]low00aromatic ether;
C-nitro compound;
monochlorobenzenes;
primary amino compound;
substituted aniline		agrochemical;
carotenoid biosynthesis inhibitor;
EC 1.3.3.4 (protoporphyrinogen oxidase) inhibitor;
herbicide
4-nitrophenyl beta-d-glucoside[no description available]low00beta-D-glucoside;
C-nitro compound		chromogenic compound
4-nitrophenyl alpha-glucoside[no description available]low00alpha-D-glucoside;
C-nitro compound;
monosaccharide derivative		chromogenic compound
bnps-skatole[no description available]low00aryl sulfide;
bromoindole;
C-nitro compound		reagent
nitrophenylgalactosides[no description available]low00beta-D-galactoside;
C-nitro compound		chromogenic compound
6-n-(2,4-dinitrophenyl)aminohexanoic acid[no description available]low00C-nitro compound
5-nitro-2-(1-piperidinyl)pyridine[no description available]low00C-nitro compound
s-(4-nitrobenzyl)glutathione[no description available]low00C-nitro compound;
organic sulfide;
S-substituted glutathione
4-nitrophenyl-2-acetamido-2-deoxy-beta-d-glucopyranoside[no description available]low00C-nitro compound;
N-acetyl-beta-D-glucosaminide		chromogenic compound
miserotoxin[no description available]low00beta-D-glucoside;
C-nitro compound		phytotoxin
aristolochic acid ii[no description available]low00aristolochic acids;
aromatic ether;
C-nitro compound;
cyclic acetal;
monocarboxylic acid;
organic heterotetracyclic compound		carcinogenic agent;
metabolite;
mutagen;
nephrotoxin;
toxin
nitisinone[no description available]low00(trifluoromethyl)benzenes;
C-nitro compound;
cyclohexanones;
mesotrione		EC 1.13.11.27 (4-hydroxyphenylpyruvate dioxygenase) inhibitor
efonidipine[no description available]low00C-nitro compound;
carboxylic ester;
dihydropyridine;
tertiary amino compound
1-(2-hydroxyethyl)-2-hydroxymethyl-5-nitroimidazole[no description available]low00C-nitro compound;
imidazoles
pyrrolomycin a[no description available]low00antibiotic antifungal agent;
C-nitro compound;
organochlorine compound;
pyrroles		antibacterial agent;
bacterial metabolite
2,8-dinitroimipramine[no description available]low00C-nitro compound;
dibenzoazepine;
tertiary amino compound
7-nitrobenzoxadiazole-6-aminohexanoic acid[no description available]low00benzoxadiazole;
C-nitro compound;
epsilon-amino acid;
secondary amino compound		fluorochrome
aristolochic acid D[no description available]low00aristolochic acids;
aromatic ether;
C-nitro compound;
cyclic acetal;
monocarboxylic acid;
organic heterotetracyclic compound		carcinogenic agent;
metabolite;
nephrotoxin;
toxin
ag 3-5[no description available]low00C-nitro compound
thymidine 5'-4-nitrophenyl phosphate[no description available]low00aryl phosphate;
C-nitro compound;
pyrimidine 2'-deoxyribonucleoside 5'-monophosphate
aristolochic acid c[no description available]low00aristolochic acids;
aromatic ether;
C-nitro compound;
cyclic acetal;
monocarboxylic acid;
organic heterotetracyclic compound		carcinogenic agent;
metabolite;
mutagen;
nephrotoxin;
toxin
mesotrione[no description available]low00aromatic ketone;
beta-triketone;
C-nitro compound;
sulfone		carotenoid biosynthesis inhibitor;
EC 1.13.11.27 (4-hydroxyphenylpyruvate dioxygenase) inhibitor;
environmental contaminant;
herbicide;
xenobiotic
3-nitrotyrosine[no description available]low002-nitrophenols;
C-nitro compound;
nitrotyrosine;
non-proteinogenic alpha-amino acid
4-[4-(3-methyl-4-nitrophenoxy)butoxy]benzonitrile[no description available]low00aromatic ether;
C-nitro compound
N-(4-nitrophenyl)-2-phenoxyacetamide[no description available]low00C-nitro compound
rubitecan[no description available]low00C-nitro compound;
delta-lactone;
pyranoindolizinoquinoline;
semisynthetic derivative;
tertiary alcohol		antineoplastic agent;
EC 5.99.1.2 (DNA topoisomerase) inhibitor;
prodrug
2-(3-nitrophenyl)-5-phenyl-1,3,4-oxadiazole[no description available]low00C-nitro compound
7-nitro-5-indeno[1,2-b]pyridinone[no description available]low00C-nitro compound
5-(4-nitrophenyl)-4-phenyl-2-thiazolamine[no description available]low00C-nitro compound
N1-(4H-1,2,4-triazol-4-yl)-4-nitrobenzamide[no description available]low00C-nitro compound
2-methoxy-4-[(4-methyl-1,4-diazepan-1-yl)methyl]-6-nitrophenol[no description available]low00aromatic ether;
C-nitro compound
N-(6-methyl-2-pyridinyl)-5-nitro-2-furancarboxamide[no description available]low00C-nitro compound;
furans
(3,5-dimethyl-1-pyrazolyl)-(2-ethyl-4-nitro-3-pyrazolyl)methanone[no description available]low00C-nitro compound
N-(4-methyl-2-pyridinyl)-5-nitro-2-furancarboxamide[no description available]low00C-nitro compound;
furans
4,5-dimethyl-2-[4-(3-nitrophenyl)-2-thiazolyl]-1H-pyrazol-3-one[no description available]low00C-nitro compound
N-methyl-2-[[4-methyl-5-[(4-nitrophenoxy)methyl]-1,2,4-triazol-3-yl]thio]acetamide[no description available]low00aromatic ether;
C-nitro compound
N-[2-(4-fluorophenyl)ethyl]-4-nitrobenzamide[no description available]low00C-nitro compound
N-(2-fluoro-5-nitrophenyl)-2,2-dimethylbutanamide[no description available]low00C-nitro compound
3-(2-methoxyphenyl)-6-(3-nitrophenyl)-1,4-dihydropyrimidin-2-one[no description available]low00C-nitro compound
3-ethyl-6-(4-nitrophenyl)-7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazine[no description available]low00C-nitro compound
5-hydroxy-7-(4-nitrophenyl)-1,3-benzoxathiol-2-one[no description available]low00C-nitro compound
1-(3,4-dimethoxyphenyl)-3-(2-methoxy-5-nitrophenyl)urea[no description available]low00aromatic ether;
C-nitro compound
N-(1-ethyl-2-benzimidazolyl)-5-[(4-methyl-2-nitrophenoxy)methyl]-2-furancarboxamide[no description available]low00aromatic ether;
C-nitro compound
2-[[cyclohexyl(oxo)methyl]amino]-4-(3-nitrophenyl)-3-thiophenecarboxylic acid ethyl ester[no description available]low00C-nitro compound
1-(3-methoxy-5-nitrophenyl)-3-(4-methylphenyl)urea[no description available]low00aromatic ether;
C-nitro compound
N-(5-tert-butyl-3-isoxazolyl)-3-nitrobenzamide[no description available]low00C-nitro compound
2-[[5-(4-nitrophenyl)-1,3,4-oxadiazol-2-yl]thio]-N-(2-pyridinyl)acetamide[no description available]low00C-nitro compound
N-(2-methyl-5-nitrophenyl)-4,6-bis(1-pyrrolidinyl)-1,3,5-triazin-2-amine[no description available]low00C-nitro compound
4-methoxy-N-[5-(4-methoxyphenyl)-4-(4-nitrophenyl)-2-thiazolyl]benzamide[no description available]low00C-nitro compound
4-methyl-2-(4-nitrophenyl)-5-thiazolecarboxylic acid[no description available]low00C-nitro compound
5-carbamoyl-4-methyl-2-[[(3-nitrophenyl)-oxomethyl]amino]-3-thiophenecarboxylic acid methyl ester[no description available]low00C-nitro compound
4-(3,5-dimethyl-4-nitro-1-pyrazolyl)butanoic acid[no description available]low00C-nitro compound
1-(3-fluorophenyl)-4-(4-hydroxy-3-methoxy-5-nitrophenyl)-4H-pyridine-3,5-dicarboxylic acid diethyl ester[no description available]low00aromatic ether;
C-nitro compound
N-[5-(4-methoxyphenyl)-4-(4-nitrophenyl)-2-thiazolyl]-4-methylbenzamide[no description available]low00C-nitro compound
1,3-dimethyl-5-[[2-[2-(4-nitrophenoxy)ethoxy]phenyl]methylidene]-1,3-diazinane-2,4,6-trione[no description available]low00aromatic ether;
C-nitro compound
stattic[no description available]low001-benzothiophenes;
C-nitro compound;
sulfone		antineoplastic agent;
radiosensitizing agent;
STAT3 inhibitor
2-fluoro-N-[2,2,2-trichloro-1-[[(4-methoxy-2-nitroanilino)-sulfanylidenemethyl]amino]ethyl]acetamide[no description available]low00aromatic ether;
C-nitro compound
2-amino-4-(4,5-dimethoxy-2-nitrophenyl)-7,7-dimethyl-5-oxo-6,8-dihydro-4H-1-benzopyran-3-carbonitrile[no description available]low00aromatic ether;
C-nitro compound
2,4-dichloro-N-[2,2,2-trichloro-1-[[(4-methoxy-2-nitroanilino)-sulfanylidenemethyl]amino]ethyl]benzamide[no description available]low00aromatic ether;
C-nitro compound
N2-tert-butyl-6-ethoxy-N4-(4-nitrophenyl)-1,3,5-triazine-2,4-diamine[no description available]low00C-nitro compound
N-[4-methyl-5-[2-(3-nitroanilino)-4-thiazolyl]-2-thiazolyl]acetamide[no description available]low00C-nitro compound
2-methyl-N-[5-(4-nitrophenyl)sulfonyl-2-thiazolyl]pentanamide[no description available]low00C-nitro compound
N-[(2-ethyl-1-piperidinyl)-sulfanylidenemethyl]-4-nitrobenzamide[no description available]low00C-nitro compound
4-[[3-methoxy-4-[(4-nitrophenyl)methoxy]phenyl]-(3-methyl-5-oxo-1,2-dihydropyrazol-4-yl)methyl]-5-methyl-1,2-dihydropyrazol-3-one[no description available]low00C-nitro compound
N-(4-chloro-3-nitrophenyl)-3-phenylbutanamide[no description available]low00C-nitro compound
3-(n,n-dimethylsulfonamido)-4-methyl-nitrobenzene[no description available]low00C-nitro compound;
sulfonamide;
toluenes		bone density conservation agent;
EC 3.1.4.53 (3',5'-cyclic-AMP phosphodiesterase) inhibitor;
geroprotector
2-[(4-chlorophenyl)sulfonyl-methylamino]-N-(4-methoxy-2-nitrophenyl)acetamide[no description available]low00aromatic ether;
C-nitro compound
1-(2-fluorophenyl)-3-(4-methoxy-2-nitrophenyl)urea[no description available]low00aromatic ether;
C-nitro compound
5-(2-nitrophenyl)-N-(2-thiazolyl)-2-furancarboxamide[no description available]low00C-nitro compound
ranitidine[no description available]low00C-nitro compound;
furans;
organic sulfide;
tertiary amino compound		anti-ulcer drug;
drug allergen;
environmental contaminant;
H2-receptor antagonist;
xenobiotic
carnidazole[no description available]low00C-nitro compound;
imidazoles
3-chloro-N-[2,2,2-trichloro-1-[[(4-methoxy-2-nitroanilino)-sulfanylidenemethyl]amino]ethyl]benzamide[no description available]low00aromatic ether;
C-nitro compound
N-methyl-5-nitro-N-(phenylmethyl)-2-furancarboxamide[no description available]low00C-nitro compound;
furans
3-nitro-N'-(2,4,6-trichlorophenyl)benzohydrazide[no description available]low00C-nitro compound
2-(2,2-dimethyl-4-oxanyl)-4-(4-nitrophenyl)thiazole[no description available]low00C-nitro compound
5-methyl-N-(3-methylphenyl)-4-nitro-1H-pyrazol-3-amine[no description available]low00C-nitro compound
3-nitro-N-[(1-oxopentylhydrazo)-sulfanylidenemethyl]benzamide[no description available]low00C-nitro compound
N-[[[2-(2-methylphenoxy)-1-oxoethyl]hydrazo]-sulfanylidenemethyl]-2-nitrobenzamide[no description available]low00C-nitro compound
N-(4-fluorophenyl)-5-nitro-2-pyridinamine[no description available]low00C-nitro compound
2-(4-chlorophenoxy)-N-(5-nitro-2-thiazolyl)acetamide[no description available]low00C-nitro compound;
thiazoles
3-methyl-4-nitro-N-(1H-1,2,4-triazol-5-yl)benzamide[no description available]low00C-nitro compound
5-nitro-2-thiophenecarboxylic acid [2-oxo-2-(1-phenylethylamino)ethyl] ester[no description available]low00C-nitro compound;
thiophenes
2-[(5-amino-1H-1,2,4-triazol-3-yl)thio]-N-(2-bromo-4-nitrophenyl)acetamide[no description available]low00C-nitro compound
4-nitrophenylhydrazine[no description available]low00C-nitro compound;
phenylhydrazines		mutagen
4-(1-azepanyl)-6-hydrazinyl-N-(4-nitrophenyl)-1,3,5-triazin-2-amine[no description available]low00C-nitro compound
2-amino-7-methyl-4-(5-nitro-2-furanyl)-5-oxo-4H-pyrano[3,2-c]pyran-3-carbonitrile[no description available]low00C-nitro compound;
furans
N4-(1,1-dioxo-3-thiolanyl)-5-nitropyrimidine-4,6-diamine[no description available]low00C-nitro compound
N4-(3-chlorophenyl)-N2-methyl-5-nitropyrimidine-2,4,6-triamine[no description available]low00C-nitro compound
4-nitrocatechol[no description available]low00C-nitro compound;
catechols		human xenobiotic metabolite;
lipoxygenase inhibitor
1-(1-naphthalenyl)-3-[[2-(2-nitrophenoxy)-1-oxoethyl]amino]urea[no description available]low00aromatic ether;
C-nitro compound
nefurthiazole[no description available]low00C-nitro compound;
furans
N-[5-(2,3-dihydro-1,4-dioxin-5-yl)-1,3,4-oxadiazol-2-yl]-5-nitro-2-thiophenecarboxamide[no description available]low00C-nitro compound;
thiophenes
2-[(4-aminophenyl)thio]-N-(3-nitrophenyl)acetamide[no description available]low00C-nitro compound
3-[4-(2-hydroxyethylamino)-3-nitrophenyl]-4-methyl-4,5-dihydro-1H-pyridazin-6-one[no description available]low00C-nitro compound
2-[[6-amino-2-(3-methylanilino)-5-nitro-4-pyrimidinyl]amino]ethanol[no description available]low00C-nitro compound
N4-(3-fluorophenyl)-N2-[3-(4-morpholinyl)propyl]-5-nitropyrimidine-2,4,6-triamine[no description available]low00C-nitro compound
3-nitro-N-(2-phenylethyl)-2-pyridinamine[no description available]low00C-nitro compound
2-(4-nitrophenyl)-4-thiazolecarboxylic acid ethyl ester[no description available]low00C-nitro compound
N-(4-bromophenyl)-5-methyl-4-nitro-1H-pyrazol-3-amine[no description available]low00C-nitro compound
3-methyl-N-[[[(4-nitrophenyl)-oxomethyl]hydrazo]-sulfanylidenemethyl]butanamide[no description available]low00C-nitro compound
5-methyl-2-[[(4-nitrophenyl)-oxomethyl]hydrazo]-4-thiazolecarboxylic acid ethyl ester[no description available]low00C-nitro compound
N-(2-chlorophenyl)-4-[[(2-methoxy-4-nitroanilino)-sulfanylidenemethyl]hydrazo]-4-oxobutanamide[no description available]low00aromatic ether;
C-nitro compound
5-nitro-2-thiophenecarboxylic acid [1-[(3,5-dichloro-2-pyridinyl)amino]-1-oxopropan-2-yl] ester[no description available]low00C-nitro compound;
thiophenes
N-[2-[(4-methyl-1,2,5-oxadiazol-3-yl)oxy]ethyl]-4-nitroaniline[no description available]low00C-nitro compound
4-nitrocaramiphen[no description available]low00C-nitro compound
4-[(3-methyl-5-nitro-4-imidazolyl)amino]phenol[no description available]low00C-nitro compound;
imidazoles
N-(2-methoxy-4-nitrophenyl)-2-[(1-methyl-2-imidazolyl)thio]acetamide[no description available]low00aromatic ether;
C-nitro compound
N2-(3-methylphenyl)-6-(4-morpholinyl)-5-nitropyrimidine-2,4-diamine[no description available]low00C-nitro compound
sb 415286[no description available]low00C-nitro compound;
maleimides;
monochlorobenzenes;
phenols;
secondary amino compound;
substituted aniline		antioxidant;
apoptosis inducer;
EC 2.7.11.26 (tau-protein kinase) inhibitor;
neuroprotective agent
N-[3-(N-(2-chloro-1-oxoethyl)-4-nitroanilino)propyl]-2,2,2-trifluoroacetamide[no description available]low00C-nitro compound;
secondary carboxamide;
tertiary carboxamide;
trifluoroacetamide
2-[[6-amino-2-[3-(dimethylamino)propylamino]-5-nitro-4-pyrimidinyl]amino]ethanol[no description available]low00C-nitro compound
4-(3-chlorophenyl)sulfonyl-N-cyclohexyl-N-methyl-3-nitrobenzamide[no description available]low00C-nitro compound
6-(2-methyl-1-piperidinyl)-5-nitro-4-pyrimidinamine[no description available]low00C-nitro compound
1-(5-nitro-2-thiophenyl)piperidine[no description available]low00C-nitro compound;
thiophenes
N-[2-(2,4,6-trinitrophenyl)ethyl]aniline[no description available]low00C-nitro compound
N2-(2-furanylmethyl)-5-nitro-6-(1-pyrrolidinyl)pyrimidine-2,4-diamine[no description available]low00C-nitro compound
1-(2,5-dimethyl-1-prop-2-enyl-3-pyrrolyl)-2-[(6-methyl-2-nitro-3-pyridinyl)oxy]ethanone[no description available]low00C-nitro compound
N-(2-bromo-4-nitrophenyl)-2-[(5-propan-2-yl-1H-1,2,4-triazol-3-yl)thio]acetamide[no description available]low00C-nitro compound
5-nitro-2-thiophenecarboxylic acid [2-oxo-2-[(phenylmethyl)amino]ethyl] ester[no description available]low00C-nitro compound;
thiophenes
2-(2,3-dihydroxypropylamino)-5-nitro-3-pyridinecarbonitrile[no description available]low00C-nitro compound
2-[(2-nitrophenyl)thio]-1-cyclooctanone[no description available]low00C-nitro compound
5-nitro-2-thiophenecarboxylic acid [2-oxo-2-[[oxo-[(phenylmethyl)amino]methyl]amino]ethyl] ester[no description available]low00C-nitro compound;
thiophenes
N2-(2-furanylmethyl)-6-(3-methyl-1-piperidinyl)-5-nitropyrimidine-2,4-diamine[no description available]low00C-nitro compound
N'-(4-nitrophenyl)-9-oxo-3-bicyclo[3.3.1]nonanecarbohydrazide[no description available]low00C-nitro compound
alsterpaullone[no description available]low00C-nitro compound;
caprolactams;
organic heterotetracyclic compound		anti-HIV-1 agent;
antineoplastic agent;
apoptosis inducer;
EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor;
EC 2.7.11.22 (cyclin-dependent kinase) inhibitor;
EC 2.7.11.26 (tau-protein kinase) inhibitor
2-(4-fluoro-3-nitrophenyl)-4,4-dimethyl-5H-oxazole[no description available]low00C-nitro compound
N'-[2-[(4-methyl-1,2,4-triazol-3-yl)sulfanyl]acetyl]-4-nitrobenzohydrazide[no description available]low00C-nitro compound
furylfuramide[no description available]low00acrylamides;
C-nitro compound;
nitrofuran antibiotic;
primary carboxamide
cilnidipine[no description available]low002-methoxyethyl ester;
C-nitro compound;
dihydropyridine		antihypertensive agent;
calcium channel blocker;
cardiovascular drug
ro 61-8048[no description available]low00C-nitro compound
meptyldinocap[no description available]low00C-nitro compound;
enoate ester
l796778[no description available]low00benzenes;
C-nitro compound;
L-lysine derivative;
L-phenylalanine derivative;
methyl ester;
oligopeptide;
secondary carboxamide;
ureas		somatostatin receptor agonist
amocarzine[no description available]low00C-nitro compound;
N-methylpiperazine;
secondary amino compound;
thioureas		antinematodal drug
nitrovin[no description available]low00C-nitro compound;
furans
dihydroxymethylfuratrizine[no description available]low00C-nitro compound;
furans
nifurpirinol[no description available]low00C-nitro compound;
furans
azanidazole[no description available]low00C-nitro compound;
imidazoles
aureothin[no description available]low004-pyranones;
C-nitro compound;
ketene acetal;
olefinic compound;
oxolanes		antibacterial agent;
antifungal agent;
antineoplastic agent;
antiparasitic agent;
bacterial metabolite;
EC 1.6.5.3 [NADH:ubiquinone reductase (H(+)-translocating)] inhibitor
nidroxyzone[no description available]low00C-nitro compound;
furans
nifurzide[no description available]low00C-nitro compound;
thiophenes
abt-737[no description available]low00aromatic amine;
aryl sulfide;
biphenyls;
C-nitro compound;
monochlorobenzenes;
N-arylpiperazine;
N-sulfonylcarboxamide;
secondary amino compound;
tertiary amino compound		anti-allergic agent;
anti-inflammatory agent;
antineoplastic agent;
apoptosis inducer;
B-cell lymphoma 2 inhibitor
5-(5-nitrothiazol-2-ylthio)-1,3,4-thiadiazol-2-amine[no description available]low001,3-thiazoles;
C-nitro compound;
organic sulfide;
primary amino compound;
thiadiazoles		antibacterial agent;
c-Jun N-terminal kinase inhibitor
[4-(2-chlorophenyl)sulfonyl-3-nitrophenyl]-[4-(phenylmethyl)-1-piperazinyl]methanone[no description available]low00C-nitro compound
2-[[5-(2-methylanilino)-1,3,4-thiadiazol-2-yl]thio]-N-(2-nitrophenyl)acetamide[no description available]low00C-nitro compound
2',3'-o-(2,4,6-trinitrophenyl)adenosine 5'-triphosphate[no description available]low00C-nitro compound;
spiroketal		antagonist
2-(4-morpholinyl)-N'-[(2-nitrophenyl)-oxomethyl]-4-thiazolecarbohydrazide[no description available]low00C-nitro compound
N'-[(2-methyl-3-nitrophenyl)-oxomethyl]-2-(4-morpholinyl)-4-thiazolecarbohydrazide[no description available]low00C-nitro compound
ML-210[no description available]low00C-nitro compound;
diarylmethane;
isoxazoles;
monochlorobenzenes;
N-acylpiperazine;
N-alkylpiperazine;
tertiary carboxamide		antineoplastic agent;
EC 1.11.1.9 (glutathione peroxidase) inhibitor;
ferroptosis inducer;
prodrug
abt-199[no description available]low00aromatic ether;
C-nitro compound;
monochlorobenzenes;
N-alkylpiperazine;
N-arylpiperazine;
N-sulfonylcarboxamide;
oxanes;
pyrrolopyridine		antineoplastic agent;
apoptosis inducer;
B-cell lymphoma 2 inhibitor
chir 98014[no description available]low00aminopyrimidine;
C-nitro compound;
diaminopyridine;
dichlorobenzene;
imidazoles;
secondary amino compound		antineoplastic agent;
apoptosis inducer;
EC 2.7.11.26 (tau-protein kinase) inhibitor;
hypoglycemic agent;
tau aggregation inhibitor;
Wnt signalling activator
acenocoumarol[no description available]low00C-nitro compound;
hydroxycoumarin;
methyl ketone		anticoagulant;
EC 1.6.5.2 [NAD(P)H dehydrogenase (quinone)] inhibitor
8-nitroguanosine 3',5'-cyclic monophosphate[no description available]low003',5'-cyclic purine nucleotide;
C-nitro compound		biomarker;
Brassica napus metabolite;
human metabolite;
signalling molecule
ConditionIndicatedRelationship StrengthStudiesTrials
Anoxemia0low10
Anoxia0low10
Benign Neoplasms0low10
Cancer0low10
Deficiency, Oxygen0low10
Hypoxemia0low10
Hypoxia0low10
Inflammation0low10
Innate Inflammatory Response0low10
Malignancy0low10
Malignant Neoplasms0low10
Neoplasia0low10
Neoplasm0low10
Neoplasms0low10
Neoplasms, Benign0low10
Oxygen Deficiency0low10
Tumors0low10