Anosmia

Complete or severe loss of the subjective sense of smell. Loss of smell may be caused by many factors such as a cold, allergy, OLFACTORY NERVE DISEASES, viral RESPIRATORY TRACT INFECTIONS (e.g., COVID-19), aging and various neurological disorders (e.g., ALZHEIMER DISEASE).

Synonym
Anosmia
Loss of Smell
Hyposmia

Excerpt	Reference
"Hyposmia is a common feature of COVID-19 and Parkinson's disease (PD)."	( Arnaldi, D; Barisione, E; Bauckneht, M; Benedetti, L; Biassoni, E; Chiola, S; D'amico, F; Donegani, MI; Gianmario, S; Lanfranchi, F; Mancini, R; Miceli, A; Morbelli, S; Nobili, F; Orso, B; Pardini, M, 2022)
"Hyposmia and anosmia are common in COVID-19."	( Boek, WM; Boesveldt, S; Kamalski, DMA; Schepens, EJA; Stegeman, I; Stokroos, RJ, 2022)
"Anosmia is the inability to smell or loss of the sense of smell."	( Alizadeh, R; Farhadi, M; Kamrava, SK; Moradi, S; Simorgh, S; Yazdian, F, 2022)
"Loss of smell is one of those neurological disorders following olfactory bulb injury after SAH."	( Akar, A; Aykora, D; Büyük, B; Malçok, ÜA; Ovali, MA; Öztopuz, RÖ, 2023)

Timeframe	Studies, This Condition (%)	All Conditions %
pre-1990	0 (0.00)	23.3326
1990's	0 (0.00)	12.5806
2000's	0 (0.00)	18.1394
2010's	0 (0.00)	28.8240
2020's	53 (100.00)	9.53

Drug	Relationship Strength	Studies	Trials
acetic acid	low	1	0
1-butanol	low	1	0
kynurenine	low	1	0
melatonin	low	1	0
sulfites	low	1	0
uric acid	low	1	0
aspirin	low	2	0
valproic acid	medium	1	1
guaifenesin	low	1	0
hydroxychloroquine	low	1	0
niclosamide	low	1	0
propofol	low	1	0
prednisolone	medium	1	1
spironolactone	low	1	0
phenylethyl alcohol	medium	1	1
tyrosine	low	1	0
tryptophan	low	1	0
arginine	low	1	0
triamcinolone acetonide	low	1	0
phencyclidine	low	1	0
cyclopentane	low	1	0
fluorodeoxyglucose f18	low	2	0
fibrinogen	low	1	0
fingolimod hydrochloride	low	1	0
proline	low	1	0
esketamine	low	1	0
cortisone	low	1	0
mometasone furoate	medium	2	2
dimethyl fumarate	low	1	0
stilbenes	low	2	0
sodium metabisulfite	low	1	0
sesquiterpenes	low	1	0
3,3',4,5'-tetrahydroxystilbene	low	1	0
capsaicin	low	1	0
cytellin	low	1	0
luteolin	low	1	0
pulmicort	medium	1	1
jasmonic acid	low	1	0
phenylephrine hydrochloride	low	3	0
fluticasone	low	1	0
rotundone	low	1	0
mocetinostat	low	1	0
2-carbomethoxy-8-(3-fluoropropyl)-3-(4-iodophenyl)tropane	low	1	0
alpha-synuclein	low	2	0
lyoniside	low	1	0
glucagon-like peptide 1	low	1	0
transforming growth factor alpha	low	1	0

Protein Targets (684)

Protein	Potency Measurements	Inhibition Measurements	Activation Measurements	Drugs
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE	8	0	0	8
aldehyde dehydrogenase 1 family, member A1	8	0	0	8
glucocorticoid receptor [Homo sapiens]	15	0	0	15
farnesoid X nuclear receptor	9	0	0	9
estrogen nuclear receptor alpha	23	0	0	23
Voltage-dependent calcium channel gamma-2 subunit	8	0	0	8
Cellular tumor antigen p53	11	0	0	11
Glutamate receptor 2	8	0	0	8
Choline O-acetyltransferase	0	1	0	2
Sodium-dependent dopamine transporter	0	2	0	2
Chain A, TYROSYL-DNA PHOSPHODIESTERASE	8	0	0	8
Chain A, Putative fructose-1,6-bisphosphate aldolase	4	0	0	4
Chain A, JmjC domain-containing histone demethylation protein 3A	3	0	0	3
Chain A, 2-oxoglutarate Oxygenase	8	0	0	8
Chain A, Ferritin light chain	3	0	0	3
Calcium dependent protein kinase	0	1	0	1
Luciferase	6	0	0	6
acid sphingomyelinase	1	0	0	1
Nrf2	1	0	0	1
thioredoxin reductase	9	0	0	9
BRCA1	2	0	0	2
phosphopantetheinyl transferase	8	0	0	8
ATAD5 protein, partial	6	0	0	6
Fumarate hydratase	4	0	0	4
GLS protein	10	0	0	10
TDP1 protein	12	0	0	12
Microtubule-associated protein tau	6	0	0	6
thioredoxin glutathione reductase	3	0	0	3
apical membrane antigen 1, AMA1	1	0	0	1
hypothetical protein, conserved	3	0	0	3
regulator of G-protein signaling 4	4	0	0	4
estrogen-related nuclear receptor alpha	17	0	0	17
polyprotein	4	0	0	4
glucocerebrosidase	5	0	0	5
luciferase	1	0	0	1
Parkin	2	0	0	2
bromodomain adjacent to zinc finger domain 2B	3	0	0	3
P53	2	0	0	2
arylsulfatase A	5	0	0	5
IDH1	8	0	0	8
euchromatic histone-lysine N-methyltransferase 2	14	0	0	14
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)	3	0	0	3
Replicase polyprotein 1ab	0	2	2	4
Bloom syndrome protein isoform 1	10	0	0	10
NPC intracellular cholesterol transporter 1 precursor	2	0	0	2
peripheral myelin protein 22 isoform 1	7	0	0	7
polyunsaturated fatty acid lipoxygenase ALOX12	2	0	0	2
D(1A) dopamine receptor	3	0	0	3
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1	5	0	0	5
atrial natriuretic peptide receptor 1 precursor	3	0	0	3
chromobox protein homolog 1	8	0	0	8
thyroid hormone receptor beta isoform a	6	0	0	6
nuclear factor erythroid 2-related factor 2 isoform 2	6	0	0	6
parathyroid hormone/parathyroid hormone-related peptide receptor precursor	4	0	0	4
DNA polymerase beta	2	0	0	2
atrial natriuretic peptide receptor 2 precursor	2	0	0	2
flap endonuclease 1	9	0	0	9
ras-related protein Rab-9A	3	0	0	3
serine/threonine-protein kinase mTOR isoform 1	2	0	0	2
FAD-linked sulfhydryl oxidase ALR	0	0	0	1
DNA polymerase eta isoform 1	2	0	0	2
DNA polymerase iota isoform a (long)	9	0	0	9
urokinase-type plasminogen activator precursor	4	0	0	4
plasminogen precursor	4	0	0	4
urokinase plasminogen activator surface receptor precursor	4	0	0	4
dual specificity tyrosine-phosphorylation-regulated kinase 1A	0	0	0	1
lethal(3)malignant brain tumor-like protein 1 isoform I	1	0	0	1
geminin	14	0	0	14
DNA polymerase kappa isoform 1	4	0	0	4
survival motor neuron protein isoform d	6	0	0	6
M-phase phosphoprotein 8	6	0	0	6
glycogen synthase kinase-3 alpha	0	0	0	1
muscleblind-like protein 1 isoform 1	3	0	0	3
histone acetyltransferase KAT2A isoform 1	1	0	0	1
DNA dC->dU-editing enzyme APOBEC-3G isoform 1	2	0	0	2
serine/threonine-protein kinase 33 isoform a	0	0	1	1
endoribonuclease toxin MazF	0	0	1	1
lamin isoform A-delta10	13	0	0	13
Polyunsaturated fatty acid lipoxygenase ALOX15B	4	0	0	4
Arginase-1	0	1	0	1
Tyrosine-protein kinase Lck	0	1	1	2
Polyunsaturated fatty acid 5-lipoxygenase	0	3	0	3
Dipeptidyl peptidase 4	0	1	0	1
ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1	0	2	0	2
Tyrosine-protein kinase SYK	0	2	2	4
Histamine H2 receptor	4	0	0	4
D(1A) dopamine receptor	2	0	0	2
Lactoylglutathione lyase	0	2	0	2
Myosin light chain kinase, smooth muscle	0	1	0	1
Arginase-1	0	2	0	2
Rap guanine nucleotide exchange factor 4	2	0	0	2
Ataxin-2	10	0	0	10
phosphoglycerate kinase	2	0	0	2
ATP-dependent phosphofructokinase	8	0	0	8
large T antigen	0	2	1	3
Free fatty acid receptor 3	0	0	1	1
Free fatty acid receptor 2	0	1	1	2
Tyrosine-protein kinase Fyn	0	0	1	1
Fibrinogen C domain-containing protein 1	0	1	0	1
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	1	1
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	1	1
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	1	1
NFKB1 protein, partial	3	0	0	3
thyroid stimulating hormone receptor	7	0	0	7
alpha-galactosidase	2	0	0	2
cytochrome P450 2C19 precursor	4	0	0	4
muscarinic acetylcholine receptor M1	6	0	0	6
lethal factor (plasmid)	6	0	0	6
Cytochrome P450 3A4	0	1	0	2
Nitric oxide synthase, endothelial	0	0	0	2
Nitric oxide synthase, brain	0	0	0	1
Nitric oxide synthase, brain	0	0	0	1
Nitric oxide synthase, inducible	0	0	0	1
Nitric oxide synthase, inducible	0	0	1	3
Cationic amino acid transporter 3	0	1	0	1
Chain A, Phospholipase A2 isoform 3	0	0	1	1
Chain A, HADH2 protein	7	0	0	7
Chain B, HADH2 protein	7	0	0	7
GTP-binding protein (rab7)	0	0	1	1
ras protein, partial	0	0	1	1
interleukin 8	2	0	0	2
AR protein	19	0	0	19
cytochrome P450 family 3 subfamily A polypeptide 4	13	0	0	13
EWS/FLI fusion protein	7	0	0	7
retinoic acid nuclear receptor alpha variant 1	14	0	0	14
cytochrome P450 2D6	9	0	0	9
peroxisome proliferator-activated receptor delta	8	0	0	8
Rac1 protein	0	0	1	1
cell division cycle 42 (GTP binding protein, 25kDa), partial	0	0	1	1
Prostaglandin-H2 D-isomerase	0	1	0	1
ATP-binding cassette sub-family C member 3	0	6	0	6
Multidrug resistance-associated protein 4	0	6	0	7
Solute carrier family 22 member 6	0	1	0	1
Prostaglandin G/H synthase 1	0	1	0	1
Prostaglandin G/H synthase 2	0	1	0	1
Bile salt export pump	0	10	0	10
Epidermal growth factor receptor	0	2	0	2
Carbonic anhydrase 1	0	5	0	7
Carbonic anhydrase 2	0	5	0	7
Fatty acid-binding protein, liver	0	2	0	2
Integrin beta-3	2	1	0	3
Myeloperoxidase	0	3	0	3
Prostaglandin G/H synthase 1	0	2	0	2
Seed linoleate 13S-lipoxygenase-1	0	3	0	5
Integrin alpha-IIb	2	1	0	3
Glutathione hydrolase 1 proenzyme	0	1	0	1
Prostaglandin G/H synthase 1	0	4	0	4
Adenosine receptor A1	0	1	0	2
Adenosine receptor A2a	0	1	0	2
Substance-P receptor	0	3	0	3
Prostaglandin G/H synthase 2	0	4	0	4
Urotensin-2 receptor	0	1	0	1
4-aminobutyrate aminotransferase, mitochondrial	0	1	0	1
Nuclear receptor ROR-gamma	4	0	0	4
Ras-related protein Rab-2A	0	0	1	1
Gamma-aminobutyric acid receptor subunit alpha-1	8	2	1	11
Prostaglandin G/H synthase 2	0	1	0	1
Rho-associated protein kinase 2	0	1	0	1
Nicotinate phosphoribosyltransferase	0	1	0	1
Solute carrier family 22 member 20	0	1	0	1
Solute carrier family 22 member 6	0	1	0	1
Canalicular multispecific organic anion transporter 1	0	6	0	6
Sigma non-opioid intracellular receptor 1	0	2	1	3
Sigma non-opioid intracellular receptor 1	0	2	1	3
pregnane X receptor	4	0	0	4
GLI family zinc finger 3	17	0	0	17
progesterone receptor	12	0	0	12
pregnane X nuclear receptor	13	0	0	13
vitamin D (1,25- dihydroxyvitamin D3) receptor	8	0	0	8
aryl hydrocarbon receptor	10	0	0	10
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a	15	0	0	15
nuclear receptor subfamily 1, group I, member 2	5	0	0	5
galanin receptor type 3	0	1	0	1
nuclear factor erythroid 2-related factor 2 isoform 1	14	0	0	14
Glucocorticoid receptor	0	15	3	24
Glycine receptor subunit alpha-1	0	14	0	14
Glycine receptor subunit beta	0	14	0	14
Glycine receptor subunit alpha-2	0	14	0	14
Glycine receptor subunit alpha-3	0	14	0	14
ORF73	0	0	1	1
15-lipoxygenase, partial	3	0	0	3
RAR-related orphan receptor gamma	14	0	0	14
estrogen receptor 2 (ER beta)	5	0	0	5
nuclear receptor subfamily 1, group I, member 3	8	0	0	8
67.9K protein	5	0	0	5
peroxisome proliferator activated receptor gamma	8	0	0	8
thyroid hormone receptor beta isoform 2	9	0	0	9
mitogen-activated protein kinase 1	2	0	0	2
nuclear receptor ROR-gamma isoform 1	6	0	0	6
peripheral myelin protein 22	4	0	0	4
cytochrome P450 3A4 isoform 1	8	0	0	8
transient receptor potential cation channel subfamily V member 1	1	0	0	1
Gamma-aminobutyric acid receptor subunit pi	8	1	1	10
Transient receptor potential cation channel subfamily V member 1	0	2	1	3
Lysine-specific histone demethylase 1A	0	1	0	1
NADH-ubiquinone oxidoreductase chain 1	0	1	0	1
Cytochrome P450 1A2	0	3	0	3
Gamma-aminobutyric acid receptor subunit beta-1	8	1	1	10
Gamma-aminobutyric acid receptor subunit delta	8	1	1	10
Gamma-aminobutyric acid receptor subunit gamma-2	8	1	1	10
Gamma-aminobutyric acid receptor subunit alpha-5	8	1	1	10
Gamma-aminobutyric acid receptor subunit alpha-3	8	1	1	10
Cannabinoid receptor 1	0	1	0	1
Acetylcholinesterase	0	3	0	3
Gamma-aminobutyric acid receptor subunit gamma-1	8	1	1	10
Gamma-aminobutyric acid receptor subunit alpha-2	8	1	1	10
Gamma-aminobutyric acid receptor subunit alpha-4	8	1	1	10
Gamma-aminobutyric acid receptor subunit gamma-3	8	1	1	10
Gamma-aminobutyric acid receptor subunit alpha-6	8	1	1	10
Cannabinoid receptor 2	0	1	0	1
Spike glycoprotein	5	1	2	8
D(2) dopamine receptor	0	0	1	1
Gamma-aminobutyric acid receptor subunit beta-3	8	1	1	10
Gamma-aminobutyric acid receptor subunit beta-2	8	1	1	10
Inositol monophosphatase 1	1	0	0	1
Potassium voltage-gated channel subfamily A member 1	0	1	1	2
Corticotropin-releasing factor receptor 2	0	1	0	1
Transient receptor potential cation channel subfamily V member 1	0	2	1	4
GABA theta subunit	8	1	1	10
Transient receptor potential cation channel subfamily V member 4	0	0	1	1
Gamma-aminobutyric acid receptor subunit epsilon	8	1	1	10
Transient receptor potential cation channel subfamily V member 2	0	0	1	1
endonuclease IV	3	0	0	3
dopamine D1 receptor	1	0	0	1
retinoid X nuclear receptor alpha	7	0	0	7
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a	5	0	0	5
v-jun sarcoma virus 17 oncogene homolog (avian)	5	0	0	5
heat shock protein beta-1	6	0	0	6
Sex hormone-binding globulin	0	0	1	1
Corticosteroid-binding globulin	0	2	0	2
TAR DNA-binding protein 43	3	0	0	3
Multidrug and toxin extrusion protein 1	0	2	0	2
Phosphodiesterase	0	1	0	1
Multidrug resistance-associated protein 5	0	0	0	1
cGMP-inhibited 3',5'-cyclic phosphodiesterase B	0	1	0	1
cGMP-inhibited 3',5'-cyclic phosphodiesterase A	0	1	0	1
Chain A, ATP-DEPENDENT DNA HELICASE Q1	2	0	0	2
vitamin D3 receptor isoform VDRA	1	0	0	1
Carbonic anhydrase 12	0	2	0	4
Carbonic anhydrase 3	0	1	0	3
Cannabinoid receptor 1	0	1	0	1
Carbonic anhydrase 4	0	2	0	4
Carbonic anhydrase 6	0	1	0	3
Carbonic anhydrase 5A, mitochondrial	0	1	0	3
Carbonic anhydrase 7	0	2	0	4
Carbonic anhydrase 9	0	1	0	3
Carbonic anhydrase 15	0	1	0	3
Carbonic anhydrase 13	0	1	0	2
Carbonic anhydrase 14	0	1	0	3
Carbonic anhydrase 5B, mitochondrial	0	1	0	3
Kelch-like ECH-associated protein 1	0	0	1	1
Nuclear factor erythroid 2-related factor 2	0	0	1	2
Glutamate receptor ionotropic, NMDA 1	0	4	0	6
Glutamate receptor ionotropic, NMDA 2A	0	3	0	5
Glutamate receptor ionotropic, NMDA 2B	0	3	0	5
Glutamate receptor ionotropic, NMDA 2C	0	3	0	6
Glutamate receptor ionotropic, NMDA 1	0	3	0	3
Glutamate receptor ionotropic, NMDA 2A	0	3	0	3
Glutamate receptor ionotropic, NMDA 2D	0	3	0	5
Glutamate receptor ionotropic, NMDA 3B	0	3	0	5
Glutamate receptor ionotropic, NMDA 3A	0	3	0	5
Sphingosine 1-phosphate receptor 1	0	0	1	1
RCG53912, isoform CRA_a	0	0	0	1
Sphingosine kinase 1	0	0	0	1
Sphingosine kinase 2	0	0	0	1
Sphingosine kinase 1	0	0	0	1
Glucagon-like peptide 1 receptor	0	0	1	1
Glucagon-like peptide 1 receptor	0	1	1	2
Glucagon receptor	0	0	1	1
Glucagon receptor	0	0	1	1
SMAD family member 2	6	0	0	6
SMAD family member 3	6	0	0	6
Rap guanine nucleotide exchange factor 3	2	0	0	2
Genome polyprotein	0	2	0	2
Spike glycoprotein	0	1	2	3
Transmembrane protease serine 2	0	1	2	3
Procathepsin L	0	1	2	3
Muscarinic acetylcholine receptor M2	0	2	0	2
Muscarinic acetylcholine receptor M4	0	1	0	1
Muscarinic acetylcholine receptor M5	0	1	0	1
Alpha-2A adrenergic receptor	0	1	0	1
Replicase polyprotein 1a	0	1	2	3
Replicase polyprotein 1ab	0	1	2	3
Replicase polyprotein 1ab	0	3	2	5
Replicase polyprotein 1ab	0	3	2	5
Muscarinic acetylcholine receptor M1	0	1	0	1
Alpha-2B adrenergic receptor	0	1	0	1
Alpha-2C adrenergic receptor	0	1	0	1
Muscarinic acetylcholine receptor M3	0	1	0	1
Alpha-1D adrenergic receptor	0	2	0	2
Potassium voltage-gated channel subfamily H member 2	0	2	0	2
Sigma intracellular receptor 2	0	1	0	1
Cyclic GMP-AMP synthase	0	1	0	1
Angiotensin-converting enzyme 2	0	1	2	3
Toll-like receptor 9	0	1	0	1
Toll-like receptor 7	0	1	0	1
Aldo-keto reductase family 1 member C4	0	1	0	1
Aldo-keto reductase family 1 member C3	0	1	0	1
Aldo-keto reductase family 1 member C2	0	1	0	1
Aldo-keto reductase family 1 member C1	0	1	0	1
Chain A, Transthyretin	0	0	1	1
Chain A, Transthyretin	0	0	1	1
Chain A, Transthyretin	0	0	1	1
Chain A, Transthyretin	0	0	1	1
Chain B, Transthyretin	0	0	1	1
Chain A, Transthyretin	0	0	1	1
Chain B, Transthyretin	0	0	1	1
Chain A, Casein kinase II subunit alpha	0	1	0	1
Chain A, Casein kinase II subunit alpha	0	1	0	1
Chain A, Casein Kinase Ii Subunit Alpha	0	1	0	1
histidine kinase	0	1	0	1
WRN	1	0	0	1
integrase, partial	0	1	0	1
lens epithelium-derived growth factor p75	0	1	0	1
USP1 protein, partial	5	0	0	5
PPM1D protein	2	0	0	2
Smad3	3	0	0	3
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	8	0	0	8
cystic fibrosis transmembrane conductance regulator ATP-binding cassette sub-family C member 7	0	0	0	1
Neuraminidase	0	2	0	2
cytochrome P450 2D6 isoform 1	3	0	0	3
lysosomal alpha-glucosidase preproprotein	2	0	0	2
galactokinase	1	0	0	1
cellular tumor antigen p53 isoform a	2	0	0	2
cytochrome P450 2C9 precursor	2	0	0	2
glycogen synthase kinase-3 beta isoform 1	0	0	1	1
importin subunit beta-1 isoform 1	1	0	0	1
snurportin-1	1	0	0	1
peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	1	0	0	1
GTP-binding nuclear protein Ran isoform 1	1	0	0	1
POsterior Segregation	0	0	1	1
Aldo-keto reductase family 1 member B10	0	1	0	1
G2/mitotic-specific cyclin-B2	0	1	0	1
Poly [ADP-ribose] polymerase tankyrase-1	0	1	0	1
Cationic trypsin	0	1	0	1
Interferon beta	9	0	0	9
Transthyretin	0	1	1	2
Interstitial collagenase	0	1	0	1
Cytochrome P450 1A1	0	3	0	3
Amyloid-beta precursor protein	0	1	0	1
Cyclin-dependent kinase 1	0	1	0	1
Chemotaxis protein CheA	0	1	0	1
Aldo-keto reductase family 1 member B1	0	4	0	4
Tyrosine-protein kinase Yes	0	1	0	1
ATP-dependent translocase ABCB1	0	2	0	2
Neutrophil elastase	0	2	0	2
72 kDa type IV collagenase	0	1	0	1
Stromelysin-1	0	2	0	2
Poly [ADP-ribose] polymerase 1	0	1	0	1
Enoyl-[acyl-carrier-protein] reductase [NADH] FabI	0	1	0	1
Alpha-amylase 1A	0	1	0	1
Androgen receptor	0	4	1	6
Sialidase	0	1	0	1
Serine/threonine-protein kinase pim-1	0	1	0	1
Fatty acid synthase	0	1	0	1
Angiotensin-converting enzyme	0	1	0	1
G2/mitotic-specific cyclin-B1	0	1	0	1
Tyrosinase	0	1	0	1
Matrix metalloproteinase-9	0	2	0	2
Urease subunit alpha	0	1	0	1
Aldo-keto reductase family 1 member B1	0	1	0	1
G2/mitotic-specific cyclin-B	0	1	0	1
Polyunsaturated fatty acid lipoxygenase ALOX15	0	1	0	1
Aldo-keto reductase family 1 member B1	0	1	0	1
Glycogen synthase kinase-3 beta	0	1	0	1
Casein kinase II subunit alpha'	0	1	0	1
Amine oxidase [flavin-containing] A	0	1	0	1
Sodium-dependent noradrenaline transporter	0	2	1	3
Sodium-dependent dopamine transporter	0	1	1	2
Cyclin-dependent kinase 2	0	1	0	1
Cruzipain	0	1	0	1
Amine oxidase [flavin-containing] B	0	1	0	1
Dipeptidyl peptidase 4	0	1	0	1
Proteasome subunit beta type-5	0	1	0	1
Cytosol aminopeptidase	0	1	0	1
Receptor-type tyrosine-protein kinase FLT3	0	2	0	2
Peroxisome proliferator-activated receptor gamma	0	0	1	1
Alpha-synuclein	1	1	0	2
Macrophage metalloelastase	0	1	0	1
Kappa-type opioid receptor	0	1	0	1
Homeobox protein Nkx-2.5	0	1	0	1
Collagenase 3	0	1	0	1
1-deoxy-D-xylulose 5-phosphate reductoisomerase	0	1	0	1
Xanthine dehydrogenase/oxidase	0	2	0	2
Fatty acid synthase	0	1	0	1
Glycogen synthase kinase-3 alpha	0	1	0	1
Glycogen synthase kinase-3 beta	0	2	0	2
Death-associated protein kinase 1	0	1	0	1
Mitogen-activated protein kinase 10	0	1	0	1
Casein kinase II subunit beta	0	1	0	1
Casein kinase II subunit alpha	0	1	0	1
Urease subunit beta	0	1	0	1
Xanthine dehydrogenase/oxidase	0	2	0	3
Cyclin-dependent kinase 6	0	1	0	1
Cyclin-dependent-like kinase 5	0	1	0	1
Cyclin homolog	0	1	0	1
Transcription factor GATA-4	0	1	0	1
Cyclin-dependent kinase 5 activator 1	0	1	0	1
Mitogen-activated protein kinase 14	0	1	0	1
Cytochrome P450 1B1	0	3	0	3
Carbonic anhydrase 3	0	1	0	1
Substance-K receptor	0	1	0	1
Integrase	0	1	0	1
Protein polybromo-1	0	0	1	1
Casein kinase II subunit alpha 3	0	1	0	1
Inositol polyphosphate multikinase	0	1	0	1
Histone-lysine N-methyltransferase SETD7	0	1	0	1
G2/mitotic-specific cyclin-B3	0	1	0	1
Enoyl-acyl-carrier protein reductase	0	2	0	2
3-oxoacyl-acyl-carrier protein reductase	0	2	0	2
Beta-hydroxyacyl-ACP dehydratase precursor (Fatty acid synthesis protein)	0	2	0	2
Aurora kinase B	0	1	0	1
MAP kinase-interacting serine/threonine-protein kinase 1	0	1	0	1
Cyclin-dependent kinase 1	0	1	0	1
Poly [ADP-ribose] polymerase tankyrase-2	0	1	0	1
MAP kinase-interacting serine/threonine-protein kinase 2	0	1	0	1
G-protein coupled receptor 35	0	1	1	2
NADPH oxidase 4	0	1	0	1
Dipeptidyl peptidase 3	0	1	0	1
Inositol hexakisphosphate kinase 2	0	1	0	1
Short transient receptor potential channel 5	0	1	0	1
Broad substrate specificity ATP-binding cassette transporter ABCG2	0	1	0	1
DNA topoisomerase 1	0	1	0	1
Zinc finger protein mex-5	0	0	1	1
Sialidase-2	0	1	0	1
M1-family alanyl aminopeptidase	0	1	0	1
Transcription factor HES-1	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4D	0	1	0	1
acetylcholinesterase	1	0	0	1
G	6	0	0	6
thyroid stimulating hormone receptor	3	0	0	3
Histone H2A.x	3	0	0	3
HLA class I histocompatibility antigen, B alpha chain	6	0	0	6
Beta-2 adrenergic receptor	0	1	0	1
Beta-1 adrenergic receptor	0	1	0	1
5-hydroxytryptamine receptor 1A	0	1	0	1
5-hydroxytryptamine receptor 2C	0	1	0	1
D(2) dopamine receptor	0	1	0	1
5-hydroxytryptamine receptor 2A	0	1	1	2
5-hydroxytryptamine receptor 1A	0	1	0	1
D(4) dopamine receptor	0	1	0	1
D(1B) dopamine receptor	0	1	0	1
Catechol O-methyltransferase	0	1	0	1
5-hydroxytryptamine receptor 1D	0	1	0	1
5-hydroxytryptamine receptor 2A	0	1	2	3
5-hydroxytryptamine receptor 2C	0	3	1	4
5-hydroxytryptamine receptor 1E	0	1	0	1
5-hydroxytryptamine receptor 2B	0	1	0	1
5-hydroxytryptamine receptor 7	0	1	0	1
5-hydroxytryptamine receptor 7	0	1	0	1
Histamine H1 receptor	0	1	0	1
D(3) dopamine receptor	0	1	0	1
5-hydroxytryptamine receptor 2B	0	3	1	4
5-hydroxytryptamine receptor 5A	0	1	0	1
5-hydroxytryptamine receptor 6	0	1	0	1
D	0	1	0	1
Inositol hexakisphosphate kinase 1	6	0	0	6
ATPase family AAA domain-containing protein 5	9	0	0	9
Sodium-dependent dopamine transporter	0	1	0	1
cytochrome P450 2C9, partial	6	0	0	6
ClpP	1	0	0	1
caspase 7, apoptosis-related cysteine protease	3	0	0	3
caspase-3	3	0	0	3
Cytochrome P450 1A2	0	1	0	1
Cholinesterase	0	1	0	1
Cytochrome P450 2C11	0	1	0	1
Cytochrome P450 2D6	0	2	0	2
Aromatase	0	1	0	1
Ribosyldihydronicotinamide dehydrogenase [quinone]	0	2	0	2
Metabotropic glutamate receptor 1	0	1	0	1
Acetylcholinesterase	0	1	0	1
Mu-type opioid receptor	0	1	0	1
Nociceptin receptor	0	1	0	1
Alpha-1A adrenergic receptor	0	1	0	1
Melatonin receptor type 1A	0	2	1	3
Melatonin receptor type 1C	0	0	1	1
Melatonin receptor type 1A	0	1	1	2
Melatonin receptor type 1B	0	2	1	3
Melatonin receptor type 1C	0	1	1	2
Melatonin receptor type 1B	0	1	1	2
Palmitoleoyl-protein carboxylesterase NOTUM	0	1	0	1
Carboxylic ester hydrolase	0	1	0	1
Histamine H3 receptor	0	1	0	1
Histone deacetylase 3	0	4	0	4
Nuclear receptor corepressor 1	0	1	0	1
Integrin beta-1	0	1	0	1
Leukotriene A-4 hydrolase	0	1	0	1
Integrin alpha-4	0	1	0	1
Cytochrome P450 2C19	0	2	0	2
Histone deacetylase 4	0	3	0	3
Histone deacetylase 1	0	4	0	4
Histone deacetylase 7	0	3	0	3
Histone deacetylase 2	0	4	0	4
Histone deacetylase 11	0	3	0	3
Histone deacetylase 8	0	3	0	3
Histone deacetylase 6	0	3	0	3
Histone deacetylase 5	0	3	0	3
Nuclear receptor corepressor 2	0	1	0	1
Chain A, Beta-lactamase	4	0	0	4
glp-1 receptor, partial	6	0	0	6
hypoxia-inducible factor 1 alpha subunit	5	0	0	5
isocitrate dehydrogenase 1, partial	1	0	0	1
activating transcription factor 6	5	0	0	5
Caspase-7	1	0	0	1
potassium voltage-gated channel subfamily H member 2 isoform d	3	0	0	3
caspase-3	1	0	0	1
DNA dC->dU-editing enzyme APOBEC-3F isoform a	1	0	0	1
Progesterone receptor	0	5	2	8
Guanine nucleotide-binding protein G	2	0	0	2
Solute carrier organic anion transporter family member 1B3	0	2	0	2
Solute carrier organic anion transporter family member 1B1	0	2	0	2
Chain A, Cruzipain	1	0	0	1
GALC protein	3	0	0	3
TSHR protein	1	0	0	1
Thrombopoietin	2	0	0	2
PINK1	1	0	0	1
nonstructural protein 1	2	0	0	2
pyruvate kinase	1	0	0	1
glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase	0	1	0	1
glucose-6-phosphate 1-dehydrogenase isoform b	0	1	0	1
histone deacetylase 9 isoform 3	2	0	0	2
huntingtin isoform 2	1	0	0	1
pyruvate kinase PKM isoform b	1	0	0	1
Aurora kinase A	0	1	0	1
3-phosphoinositide-dependent protein kinase 1	0	1	0	1
Tyrosine-protein kinase JAK2	0	1	0	1
Tyrosine-protein kinase ABL1	0	1	0	1
Tyrosine-protein kinase Lyn	0	1	0	1
Ornithine decarboxylase	1	0	0	1
Platelet-derived growth factor receptor beta	0	1	0	1
Mast/stem cell growth factor receptor Kit	0	1	0	1
Fibroblast growth factor receptor 1	0	1	0	1
Proto-oncogene tyrosine-protein kinase Src	0	1	0	1
Serine/threonine-protein kinase B-raf	0	1	0	1
Protein kinase C alpha type	0	1	0	1
Mitogen-activated protein kinase 1	0	1	0	1
RAC-alpha serine/threonine-protein kinase	0	1	0	1
Vascular endothelial growth factor receptor 2	0	1	0	1
Signal transducer and activator of transcription 3	0	1	0	1
Mitogen-activated protein kinase 8	0	1	0	1
Angiopoietin-1 receptor	0	1	0	1
Anoctamin-1	0	1	0	1
Chain A, Immunoglobulin	0	0	1	1
Chain B, Immunoglobulin	0	0	1	1
Glutamate receptor ionotropic, NMDA 2D	0	1	0	1
Glutamate receptor ionotropic, NMDA 3B	0	1	0	1
Muscarinic acetylcholine receptor M1	0	0	1	1
Muscarinic acetylcholine receptor M3	0	0	1	1
Muscarinic acetylcholine receptor M4	0	0	1	1
Muscarinic acetylcholine receptor M5	0	0	1	1
Muscarinic acetylcholine receptor M2	0	0	1	1
Muscarinic acetylcholine receptor M1	0	0	1	2
Cytochrome P450 2B6	0	1	0	1
Sodium-dependent serotonin transporter	0	3	0	3
Muscarinic acetylcholine receptor M4	0	0	1	2
Delta-type opioid receptor	0	0	0	1
Kappa-type opioid receptor	0	0	0	1
Lysosomal Pro-X carboxypeptidase	0	1	0	1
Mu-type opioid receptor	0	0	0	1
Cholinesterase	0	1	0	1
Glutamate receptor ionotropic, NMDA 2B	0	2	0	2
Glutamate receptor ionotropic, NMDA 2C	0	1	0	1
Glutamate receptor ionotropic, NMDA 3A	0	1	0	1
Muscarinic acetylcholine receptor M5	0	0	1	2
Muscarinic acetylcholine receptor M3	0	0	1	2
Muscarinic acetylcholine receptor M2	0	0	1	2
beta-2 adrenergic receptor	1	0	0	1
mu-type opioid receptor isoform MOR-1	0	0	1	1
Vpr	2	0	0	2
5-hydroxytryptamine receptor 2A	0	0	1	1
Neuronal acetylcholine receptor subunit alpha-4	1	0	0	1
Neuronal acetylcholine receptor subunit beta-2	1	0	0	1
luciferase	0	0	0	1
Estrogen receptor	0	5	1	6
Glucocorticoid receptor	0	2	1	3
Glucocorticoid receptor	0	0	1	1
Mineralocorticoid receptor	0	5	2	8
Cytochrome P450 2C9	0	2	0	2
Glutamine synthetase	0	0	1	1
Androgen receptor	0	5	0	6
Histamine H1 receptor	0	0	1	1
Nociceptin receptor	0	0	1	1
Cytochrome P450 2J2	0	2	0	2
Estrogen receptor beta	0	4	1	5
Glutamate 5-kinase	0	0	0	1
Angiotensin-converting enzyme	0	1	0	1
Neutral amino acid transporter A	0	1	0	1
Neutral amino acid transporter B(0)	0	1	0	1
Proton-coupled amino acid transporter 1	0	1	0	1
Amino acid transporter	0	1	0	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Fatty-acid amide hydrolase 1	0	1	0	1
UDP-glucuronosyltransferase 1A9	0	0	0	2
5-hydroxytryptamine receptor 4	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-1	0	0	0	1
Gamma-aminobutyric acid receptor subunit beta-1	0	0	0	1
Gamma-aminobutyric acid receptor subunit alpha-2	0	0	0	1
Gamma-aminobutyric acid receptor subunit alpha-3	0	0	0	1
Polyunsaturated fatty acid lipoxygenase ALOX15	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-1	0	1	1	2
Gamma-aminobutyric acid receptor subunit beta-1	0	0	1	1
Gamma-aminobutyric acid receptor subunit gamma-2	0	1	1	2
Gamma-aminobutyric acid receptor subunit alpha-4	0	0	0	1
Gamma-aminobutyric acid receptor subunit gamma-2	0	0	0	1
Sodium- and chloride-dependent GABA transporter 1	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-3	0	1	1	2
Gamma-aminobutyric acid receptor subunit alpha-5	0	0	1	1
Sodium- and chloride-dependent GABA transporter 2	0	1	0	1
Sodium- and chloride-dependent GABA transporter 3	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-3	0	0	1	1
Gamma-aminobutyric acid receptor subunit alpha-2	0	0	1	1
Gamma-aminobutyric acid receptor subunit beta-2	0	0	1	1
Sodium- and chloride-dependent betaine transporter	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-4	0	0	1	1
Fatty-acid amide hydrolase 1	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-6	0	0	1	1
UDP-glucuronosyltransferase 1A8	0	0	0	1
Interleukin-5	0	1	0	1
Interleukin-5	0	1	0	1
Interleukin-5 receptor subunit alpha	0	1	0	1
Chain A, Mineralocorticoid receptor	0	1	0	1
Chain A, Mineralocorticoid receptor	0	1	0	1
Tyrosinase	0	1	0	1
NAD(P)H dehydrogenase [quinone] 1	0	0	0	1
procathepsin L isoform 1 preproprotein	0	1	0	1
Chain A, Trp Rna-binding Attenuation Protein	0	0	1	1
Chain K, Trp Rna-binding Attenuation Protein	0	0	1	1
Chain B, tryptophanyl-tRNA synthetase	0	0	1	1
Chain C, Tryptophanyl-tRNA synthetase II	0	0	1	1
histone-lysine N-methyltransferase 2A isoform 2 precursor	1	0	0	1
Dihydrofolate reductase	0	2	0	2
Plasma kallikrein	0	0	0	2
Alkaline phosphatase, tissue-nonspecific isozyme	0	1	0	1
Intestinal-type alkaline phosphatase	0	1	0	1
Indoleamine 2,3-dioxygenase 1	0	1	0	2
Carbonic anhydrase	0	0	0	2
Tryptophan 2,3-dioxygenase	0	1	0	2
Carbonic anhydrase	0	0	0	2
Large neutral amino acids transporter small subunit 1	0	2	0	2
SLC16A10 protein	0	0	0	2
Uracil nucleotide/cysteinyl leukotriene receptor	0	1	0	1
Carbonic anhydrase	0	0	0	2
Carbonic anhydrase-like protein, putative	0	0	0	2
Tryprostatin B synthase	0	0	0	1
Carbonic anhydrase	0	0	0	2
Carbonic anhydrase	0	0	0	2
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase	0	0	1	1
Carbonic anhydrase	0	0	0	2
Monocarboxylate transporter 10	0	0	0	2
Phospholipase A-2-activating protein	0	1	0	1
Chain A, CHORISMATE MUTASE	0	1	0	1
Chain A, TYROSYL-tRNA SYNTHETASE	0	0	1	1
Polyphenol oxidase 2	0	0	0	1
Tubulin--tyrosine ligase	0	1	0	1
Taste receptor type 2 member 14	0	0	0	1
Chain A, Glycogen phosphorylase, liver form	0	0	1	1
Chain A, glycogen phosphorylase, liver form	0	0	1	1
Chain A, Glycogen phosphorylase, liver form	0	0	1	1
Chain A, Glycogen phosphorylase, liver form	0	0	1	1
Solute carrier family 22 member 6	0	0	0	1
Solute carrier family 22 member 8	0	1	0	1
Solute carrier family 2, facilitated glucose transporter member 9	0	1	1	2
Guanine deaminase	0	1	0	1
Cocaine esterase	0	1	0	1
Bile salt export pump	0	1	0	1
Cytochrome P450 2A6	0	1	0	1
Tissue factor	0	1	0	1
Aldo-keto reductase family 1 member A1	0	1	0	1
UDP-glucuronosyltransferase 2B7	0	1	0	2
UDP-glucuronosyltransferase 1-6	0	0	0	1
Liver carboxylesterase 1	0	1	0	1
Aldo-keto reductase family 1 member A1	0	1	0	1
Aldo-keto reductase family 1 member A1	0	1	0	1
Aldo-keto reductase family 1 member B7	0	1	0	1
Sigma non-opioid intracellular receptor 1	0	1	0	1
Polyamine deacetylase HDAC10	0	2	0	2
NAD-dependent protein deacylase sirtuin-5, mitochondrial	0	1	0	1
Histone deacetylase 9	0	2	0	2
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Synonyms(3)

Research Excerpts

Overview

Research

Studies (53)

Protein Targets (684)

Anosmia

Synonyms(3)

Research Excerpts

Overview

Research

Studies (53)

Drugs Studied (60)

Protein Targets (684)