Roles > UDP-glucuronosyltransferase activator
Page last updated: 2024-08-05 15:19:54

UDP-glucuronosyltransferase activator

Any compound that activates UDP-glucuronosyltransferase (EC 2.4.1.17).

ChEBI ID: 77324

Members (1)

MemberDefinitionClass
ethoxyquinA quinoline that is 1,2-dihydroquinoline bearing three methyl substituents at position 2, 2 and 4 as well as an ethoxy substituent at position 6.ethoxyquin

Research

Studies (237)

TimeframeStudies, Drugs with This Role(%)All Drugs %
pre-1990113 (47.68)18.7374
1990's48 (20.25)18.2507
2000's32 (13.50)29.6817
2010's31 (13.08)24.3611
2020's13 (5.49)2.80

Study Types

Publication TypeStudies, Drugs with this Role (%)All Drugs (%)
Trials1 (0.40%)5.53%
Reviews11 (4.35%)6.00%
Case Studies8 (3.16%)4.05%
Observational0 (0.00%)0.25%
Other233 (92.09%)84.16%

Protein Targets (82)

Potency Measurements

ProteinTaxonomyMeasurementAverage (mM)Bioassay(s)Drugs
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1Homo sapiens (human)Potency17.073913
15-lipoxygenase, partialHomo sapiens (human)Potency18.854112
acid sphingomyelinaseHomo sapiens (human)Potency25.118911
activating transcription factor 6Homo sapiens (human)Potency50.870423
aldehyde dehydrogenase 1 family, member A1Homo sapiens (human)Potency25.998213
apical membrane antigen 1, AMA1Plasmodium falciparum 3D7Potency22.387211
AR proteinHomo sapiens (human)Potency39.1535810
aryl hydrocarbon receptorHomo sapiens (human)Potency17.358325
bromodomain adjacent to zinc finger domain 2BHomo sapiens (human)Potency50.118711
caspase-3Cricetulus griseus (Chinese hamster)Potency68.415312
Caspase-7Cricetulus griseus (Chinese hamster)Potency68.415312
Cellular tumor antigen p53Homo sapiens (human)Potency42.066424
Chain A, 2-oxoglutarate OxygenaseHomo sapiens (human)Potency18.854112
Chain A, HADH2 proteinHomo sapiens (human)Potency20.003424
Chain A, JmjC domain-containing histone demethylation protein 3AHomo sapiens (human)Potency44.668411
Chain A, Putative fructose-1,6-bisphosphate aldolaseGiardia intestinalisPotency17.740711
Chain A, TYROSYL-DNA PHOSPHODIESTERASEHomo sapiens (human)Potency36.253012
Chain B, HADH2 proteinHomo sapiens (human)Potency20.003424
cytochrome P450 2C19 precursorHomo sapiens (human)Potency0.050111
cytochrome P450 2C9 precursorHomo sapiens (human)Potency1.995311
cytochrome P450 2D6 isoform 1Homo sapiens (human)Potency2.511911
cytochrome P450 3A4 isoform 1Homo sapiens (human)Potency14.219124
estrogen nuclear receptor alphaHomo sapiens (human)Potency29.209568
estrogen-related nuclear receptor alphaHomo sapiens (human)Potency47.704122
euchromatic histone-lysine N-methyltransferase 2Homo sapiens (human)Potency8.912511
farnesoid X nuclear receptorHomo sapiens (human)Potency44.668411
flap endonuclease 1Homo sapiens (human)Potency35.481311
GABA theta subunitRattus norvegicus (Norway rat)Potency14.219112
Gamma-aminobutyric acid receptor subunit alpha-1Rattus norvegicus (Norway rat)Potency14.219112
Gamma-aminobutyric acid receptor subunit alpha-2Rattus norvegicus (Norway rat)Potency14.219112
Gamma-aminobutyric acid receptor subunit alpha-3Rattus norvegicus (Norway rat)Potency14.219112
Gamma-aminobutyric acid receptor subunit alpha-4Rattus norvegicus (Norway rat)Potency14.219112
Gamma-aminobutyric acid receptor subunit alpha-5Rattus norvegicus (Norway rat)Potency14.219112
Gamma-aminobutyric acid receptor subunit alpha-6Rattus norvegicus (Norway rat)Potency14.219112
Gamma-aminobutyric acid receptor subunit beta-1Rattus norvegicus (Norway rat)Potency14.219112
Gamma-aminobutyric acid receptor subunit beta-2Rattus norvegicus (Norway rat)Potency14.219112
Gamma-aminobutyric acid receptor subunit beta-3Rattus norvegicus (Norway rat)Potency14.219112
Gamma-aminobutyric acid receptor subunit deltaRattus norvegicus (Norway rat)Potency14.219112
Gamma-aminobutyric acid receptor subunit epsilonRattus norvegicus (Norway rat)Potency14.219112
Gamma-aminobutyric acid receptor subunit gamma-1Rattus norvegicus (Norway rat)Potency14.219112
Gamma-aminobutyric acid receptor subunit gamma-2Rattus norvegicus (Norway rat)Potency14.219112
Gamma-aminobutyric acid receptor subunit gamma-3Rattus norvegicus (Norway rat)Potency14.219112
Gamma-aminobutyric acid receptor subunit piRattus norvegicus (Norway rat)Potency14.219112
gemininHomo sapiens (human)Potency26.608611
GLI family zinc finger 3Homo sapiens (human)Potency47.531124
glucocorticoid receptor [Homo sapiens]Homo sapiens (human)Potency61.644811
heat shock protein beta-1Homo sapiens (human)Potency58.145912
Histamine H2 receptorCavia porcellus (domestic guinea pig)Potency7.309227
Histone H2A.xCricetulus griseus (Chinese hamster)Potency15.884511
hypothetical protein, conservedTrypanosoma bruceiPotency31.622811
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)Homo sapiens (human)Potency1.258922
lamin isoform A-delta10Homo sapiens (human)Potency7.508412
LuciferasePhotinus pyralis (common eastern firefly)Potency59.683212
Nrf2Homo sapiens (human)Potency19.952611
nuclear factor erythroid 2-related factor 2 isoform 1Homo sapiens (human)Potency52.960647
Nuclear receptor ROR-gammaHomo sapiens (human)Potency42.163211
nuclear receptor ROR-gamma isoform 1Mus musculus (house mouse)Potency6.309611
nuclear receptor subfamily 1, group I, member 3Homo sapiens (human)Potency20.422136
peroxisome proliferator activated receptor gammaHomo sapiens (human)Potency40.543159
peroxisome proliferator-activated receptor deltaHomo sapiens (human)Potency44.547145
phosphopantetheinyl transferaseBacillus subtilisPotency50.118711
polyunsaturated fatty acid lipoxygenase ALOX12Homo sapiens (human)Potency12.589311
Polyunsaturated fatty acid lipoxygenase ALOX15BHomo sapiens (human)Potency11.294712
pregnane X nuclear receptorHomo sapiens (human)Potency48.975123
pregnane X receptorRattus norvegicus (Norway rat)Potency45.857712
progesterone receptorHomo sapiens (human)Potency30.753812
RAR-related orphan receptor gammaMus musculus (house mouse)Potency43.057211
retinoic acid nuclear receptor alpha variant 1Homo sapiens (human)Potency54.827636
retinoid X nuclear receptor alphaHomo sapiens (human)Potency26.672935
SMAD family member 2Homo sapiens (human)Potency38.731724
SMAD family member 3Homo sapiens (human)Potency38.731724
Smad3Homo sapiens (human)Potency2.238711
TDP1 proteinHomo sapiens (human)Potency23.040123
thioredoxin glutathione reductaseSchistosoma mansoniPotency89.125111
thioredoxin reductaseRattus norvegicus (Norway rat)Potency89.125111
thyroid hormone receptor beta isoform 2Rattus norvegicus (Norway rat)Potency54.410925
thyroid hormone receptor beta isoform aHomo sapiens (human)Potency50.118711
USP1 protein, partialHomo sapiens (human)Potency26.632022
v-jun sarcoma virus 17 oncogene homolog (avian)Homo sapiens (human)Potency46.822624
vitamin D (1,25- dihydroxyvitamin D3) receptorHomo sapiens (human)Potency51.208047
vitamin D3 receptor isoform VDRAHomo sapiens (human)Potency38.145612
VprHuman immunodeficiency virus 1Potency0.794311
chemdatabank.com