Any antigen that is a phosphorylated microbial metabolite which activates an immune response in humans.
ChEBI ID: 59544
| Member | Definition | Class |
|---|---|---|
| (e)-4-hydroxy-3-methylbut-2-enyl diphosphate | A prenol phosphate comprising (2E)-4-hydroxy-3-methylbut-2-en-1-ol having an O-diphosphate substituent. | (2E)-4-hydroxy-3-methylbut-2-en-1-yl diphosphate |
| 3,3-dimethylallyl pyrophosphate | A prenol phosphate that is a phosphoantigen comprising the O-pyrophosphate of prenol. | prenyl diphosphate |
| bromohydrin pyrophosphate | An alkyl diphosphate having bromohydrin as the alkyl group. | bromohydrin pyrophosphate |
| isopentenyl pyrophosphate | A prenol phosphate comprising 3-methylbut-3-en-1-ol having an O-diphosphate substituent. | isopentenyl diphosphate |
| methylphosphate | A monoalkyl phosphate having methyl as the alkyl group. | methyl dihydrogen phosphate |
| monoethyl phosphate | A monoalkyl phosphate epitope having ethyl as the alkyl group. | ethyl dihydrogen phosphate |
| Timeframe | Studies, Drugs with This Role(%) | All Drugs % |
|---|---|---|
| pre-1990 | 39 (6.49) | 18.7374 |
| 1990's | 76 (12.65) | 18.2507 |
| 2000's | 219 (36.44) | 29.6817 |
| 2010's | 226 (37.60) | 24.3611 |
| 2020's | 41 (6.82) | 2.80 |
| Publication Type | Studies, Drugs with this Role (%) | All Drugs (%) |
|---|---|---|
| Trials | 3 (0.41%) | 5.53% |
| Reviews | 67 (9.19%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 659 (90.40%) | 84.16% |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|---|---|---|---|---|
| Butyrophilin subfamily 3 member A1 | Homo sapiens (human) | IC50 | 104.1667 | 10 | 12 |
| Chain A, Isopentenyl-diphosphate delta-isomerase | Escherichia coli | IC50 | 50.0000 | 1 | 1 |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|---|---|---|---|---|
| Butyrophilin subfamily 3 member A1 | Homo sapiens (human) | EC50 | 9.1256 | 8 | 12 |
| Butyrophilin subfamily 3 member A1 | Homo sapiens (human) | Kd | 2.9050 | 2 | 2 |
| Chain A, Undecaprenyl pyrophosphate synthetase | Escherichia coli | Kd | 520.0000 | 1 | 1 |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|---|---|---|---|---|
| Butyrophilin subfamily 3 member A1 | Homo sapiens (human) | ED50 | 100.0000 | 1 | 1 |
| Tryptophan dimethylallyltransferase | Aspergillus fumigatus Af293 | Km | 140.0000 | 1 | 1 |