A compound that inhibits the oxidation of any fatty acid.
ChEBI ID: 133190
| Member | Definition | Class |
|---|---|---|
| 2-bromopalmitate | A bromo fatty acid that is hexadecanoic (palmitic) acid carrying a single bromo substituent at position 2. | 2-bromohexadecanoic acid |
| Timeframe | Studies, Drugs with This Role(%) | All Drugs % |
|---|---|---|
| pre-1990 | 10 (7.41) | 18.7374 |
| 1990's | 24 (17.78) | 18.2507 |
| 2000's | 47 (34.81) | 29.6817 |
| 2010's | 43 (31.85) | 24.3611 |
| 2020's | 11 (8.15) | 2.80 |
| Publication Type | Studies, Drugs with this Role (%) | All Drugs (%) |
|---|---|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 2 (1.44%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 137 (98.56%) | 84.16% |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|---|---|---|---|---|
| activating transcription factor 6 | Homo sapiens (human) | Potency | 34.6654 | 1 | 1 |
| AR protein | Homo sapiens (human) | Potency | 28.9477 | 2 | 2 |
| Cellular tumor antigen p53 | Homo sapiens (human) | Potency | 58.5736 | 2 | 2 |
| estrogen nuclear receptor alpha | Homo sapiens (human) | Potency | 35.9454 | 4 | 4 |
| farnesoid X nuclear receptor | Homo sapiens (human) | Potency | 24.5412 | 1 | 1 |
| glucocorticoid receptor [Homo sapiens] | Homo sapiens (human) | Potency | 55.6575 | 3 | 3 |
| heat shock protein beta-1 | Homo sapiens (human) | Potency | 22.9934 | 2 | 2 |
| hypoxia-inducible factor 1 alpha subunit | Homo sapiens (human) | Potency | 50.4169 | 2 | 2 |
| Luciferase | Photinus pyralis (common eastern firefly) | Potency | 89.3584 | 1 | 1 |
| nuclear factor erythroid 2-related factor 2 isoform 1 | Homo sapiens (human) | Potency | 28.6886 | 4 | 4 |
| nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a | Homo sapiens (human) | Potency | 34.6654 | 1 | 1 |
| nuclear receptor subfamily 1, group I, member 3 | Homo sapiens (human) | Potency | 22.1396 | 2 | 2 |
| peroxisome proliferator activated receptor gamma | Homo sapiens (human) | Potency | 36.6167 | 4 | 4 |
| Peroxisome proliferator-activated receptor alpha | Homo sapiens (human) | Potency | 14.1254 | 1 | 1 |
| peroxisome proliferator-activated receptor delta | Homo sapiens (human) | Potency | 19.5681 | 3 | 3 |
| RAR-related orphan receptor gamma | Mus musculus (house mouse) | Potency | 68.5896 | 2 | 2 |
| retinoid X nuclear receptor alpha | Homo sapiens (human) | Potency | 31.6228 | 1 | 1 |
| thyroid hormone receptor beta isoform 2 | Rattus norvegicus (Norway rat) | Potency | 69.9313 | 2 | 2 |
| thyroid hormone receptor beta isoform a | Homo sapiens (human) | Potency | 50.1187 | 1 | 1 |
| vitamin D (1,25- dihydroxyvitamin D3) receptor | Homo sapiens (human) | Potency | 27.5357 | 1 | 1 |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|---|---|---|---|---|
| Palmitoyltransferase ZDHHC2 | Homo sapiens (human) | IC50 | 2.0200 | 1 | 1 |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|---|---|---|---|---|
| Peroxisome proliferator-activated receptor delta | Homo sapiens (human) | EC50 | 3.7200 | 1 | 1 |