Roles > voltage-dependent anion channel inhibitor
Page last updated: 2024-08-05 15:48:24
voltage-dependent anion channel inhibitor
Any agent that inhibits voltage-dependent anion channels.
ChEBI ID: 173100
Members (1)
| Member | Definition | Class |
|---|
| erastin | A member of the class of quinazolines that is quinazolin-4(3H)-one in which the hydrogens at positions 2 and 3 are replaced by 1-{4-[(4-chlorophenoxy)acetyl]piperazin-1-yl}ethyl and 2-ethoxyphenyl groups, respectively. It is an inhibitor of voltage-dependent anion-selective channels (VDAC2 and VDAC3) and a potent ferroptosis inducer. | erastin |
Research
Studies (208)
| Timeframe | Studies, Drugs with This Role(%) | All Drugs % |
|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 5 (2.40) | 29.6817 |
| 2010's | 83 (39.90) | 24.3611 |
| 2020's | 120 (57.69) | 2.80 |
Study Types
| Publication Type | Studies, Drugs with this Role (%) | All Drugs (%) |
|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 9 (4.25%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 203 (95.75%) | 84.16% |
Protein Targets (10)
Potency Measurements
Inhibition Measurements
Activation Measurements
Other Measurements