Roles > progesterone receptor modulator
Page last updated: 2024-08-05 15:39:55
progesterone receptor modulator
A hormone receptor modulator that acts as a complete or partial agonist or as an antagonist at the progesterone receptor.
ChEBI ID: 71027
Members (1)
| Member | Definition | Class |
|---|
| ulipristal acetate | A 20-oxo steroid obtained by acetylation of the 17-hydroxy group of (11beta,17alpha)-17-acetyl-11-[4-(dimethylamino)phenyl]-3-oxoestra-4,9-dien-17-ol (ulipristal). A selective progesterone receptor modulator, which is employed as an emergency contraceptive. | ulipristal acetate |
Research
Studies (353)
| Timeframe | Studies, Drugs with This Role(%) | All Drugs % |
|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (0.28) | 18.2507 |
| 2000's | 2 (0.57) | 29.6817 |
| 2010's | 275 (77.90) | 24.3611 |
| 2020's | 75 (21.25) | 2.80 |
Study Types
| Publication Type | Studies, Drugs with this Role (%) | All Drugs (%) |
|---|
| Trials | 41 (10.90%) | 5.53% |
| Reviews | 102 (27.13%) | 6.00% |
| Case Studies | 34 (9.04%) | 4.05% |
| Observational | 22 (5.85%) | 0.25% |
| Other | 177 (47.07%) | 84.16% |
Protein Targets (1)
Inhibition Measurements
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|
| Progesterone receptor | Homo sapiens (human) | IC50 | 0.0002 | 1 | 1 |
Activation Measurements
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|
| Progesterone receptor | Homo sapiens (human) | EC50 | 0.1000 | 1 | 1 |