Roles > neuropilin receptor antagonist
Page last updated: 2024-08-05 15:50:04
neuropilin receptor antagonist
An antagonist that binds to and deactivates neuropilin receptors.
ChEBI ID: 166909
Members (1)
Member | Definition | Class |
EG00229 | A member of the class of thiophenes that is thiophene substituted by a carbonyl-L-arginine and (2,1,3-benzothiadiazole-4-sulfonyl)amino groups at positions 2 and 3. It is an inhibitor of the neuropilin-1 and VEGF-A interaction and a potential anti-cancer agent. | EG00229 |
Research
Studies (6)
Timeframe | Studies, Drugs with This Role(%) | All Drugs % |
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 3 (50.00) | 24.3611 |
2020's | 3 (50.00) | 2.80 |
Study Types
Publication Type | Studies, Drugs with this Role (%) | All Drugs (%) |
Trials | 0 (0.00%) | 5.53% |
Reviews | 0 (0.00%) | 6.00% |
Case Studies | 0 (0.00%) | 4.05% |
Observational | 0 (0.00%) | 0.25% |
Other | 6 (100.00%) | 84.16% |
Protein Targets (6)
Potency Measurements
Inhibition Measurements
Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
Neuropilin-1 | Homo sapiens (human) | IC50 | 9.1833 | 6 | 6 |