Any glycine transporter inhibitor that interferes with the action of glycine 2 transporters.
ChEBI ID: 85424
| Member | Definition | Class |
|---|---|---|
| oleoylcarnitine | An O-acyl-L-carnitine in which the acyl group is specified as oleoyl. | (R)-oleoylcarnitine |
| yoda 1 | A member of the class of thiadiazoles that is 1,3,4-thiadiazole substituted by pyrazin-2-yl and (2,6-dichlorobenzyl)sulfanediyl groups at positions 2 and 5, respectively. It is a selective activator of mechanosensitive channel piezo1. | yoda 1 |
| Timeframe | Studies, Drugs with This Role(%) | All Drugs % |
|---|---|---|
| pre-1990 | 2 (6.25) | 18.7374 |
| 1990's | 2 (6.25) | 18.2507 |
| 2000's | 1 (3.13) | 29.6817 |
| 2010's | 9 (28.13) | 24.3611 |
| 2020's | 18 (56.25) | 2.80 |
| Publication Type | Studies, Drugs with this Role (%) | All Drugs (%) |
|---|---|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 1 (3.13%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 31 (96.88%) | 84.16% |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|---|---|---|---|---|
| Sodium- and chloride-dependent glycine transporter 2 | Homo sapiens (human) | IC50 | 0.3400 | 1 | 1 |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|---|---|---|---|---|
| Piezo-type mechanosensitive ion channel component 1 | Homo sapiens (human) | EC50 | 26.6000 | 1 | 1 |