Roles > glucagon-like peptide-1 receptor agonist
Page last updated: 2024-08-05 15:49:17
glucagon-like peptide-1 receptor agonist
An agonist that binds to and activates glucagon-like peptide-1 (GLP-1) receptors.
ChEBI ID: 71196
Members (2)
| Member | Definition | Class |
|---|
| liraglutide | A lipopeptide that is an analogue of human GLP-1 in which the lysine residue at position 27 is replaced by arginine and a hexadecanoyl group attached to the remaining lysine via a glutamic acid spacer. Used as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus. | liraglutide |
| semaglutide | A polypeptide that contains a linear sequence of 31 amino acids joined together by peptide linkages. It is an agonist of glucagon-like peptide-1 receptors (GLP-1 AR) and used for the treatment of type 2 diabetes. | semaglutide |
Research
Studies (2,810)
| Timeframe | Studies, Drugs with This Role(%) | All Drugs % |
|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 112 (3.99) | 29.6817 |
| 2010's | 1,579 (56.19) | 24.3611 |
| 2020's | 1,119 (39.82) | 2.80 |
Study Types
| Publication Type | Studies, Drugs with this Role (%) | All Drugs (%) |
|---|
| Trials | 582 (19.54%) | 5.53% |
| Reviews | 624 (20.95%) | 6.00% |
| Case Studies | 96 (3.22%) | 4.05% |
| Observational | 63 (2.12%) | 0.25% |
| Other | 1,613 (54.16%) | 84.16% |
Protein Targets (1)
Inhibition Measurements
Activation Measurements