Any inhibitor that acts on insulin-like growth factor-binding proteins.
ChEBI ID: 195444
| Member | Definition | Class |
|---|---|---|
| nbi 31772 | An isoquinoline substituted by 3,4-dihydroxybenzoyl, carboxy, hydroxy, and hydroxy groups at positions 1, 3, 6, and 7, respectively. It is a potent inhibitor of insulin-like growth factor-1 binding protein (IGFBP). | NBI-31772 |
| Timeframe | Studies, Drugs with This Role(%) | All Drugs % |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 11 (78.57) | 29.6817 |
| 2010's | 2 (14.29) | 24.3611 |
| 2020's | 1 (7.14) | 2.80 |
| Publication Type | Studies, Drugs with this Role (%) | All Drugs (%) |
|---|---|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 0 (0.00%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 14 (100.00%) | 84.16% |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|---|---|---|---|---|
| Insulin-like growth factor-binding protein 1 | Homo sapiens (human) | Ki | 0.0051 | 1 | 1 |
| Insulin-like growth factor-binding protein 2 | Homo sapiens (human) | Ki | 0.0021 | 1 | 1 |
| Insulin-like growth factor-binding protein 3 | Homo sapiens (human) | Ki | 0.0056 | 2 | 2 |
| Insulin-like growth factor-binding protein 4 | Homo sapiens (human) | Ki | 0.0010 | 1 | 1 |
| Insulin-like growth factor-binding protein 5 | Homo sapiens (human) | Ki | 0.0054 | 2 | 2 |
| Insulin-like growth factor-binding protein 6 | Homo sapiens (human) | Ki | 0.0236 | 1 | 1 |