Rib Fractures

Synonym
Rib Fractures

Excerpt	Reference
"Rib fractures are very common in closed chest injuries."	( Calatayud Moscoso Del Prado, J; Choren Durán, ML; Delgado Sánchez-Gracián, C; Leal Ruiloba, S; Lozano Gómez, M; Moreno De La Santa Barajas, P; Polo Otero, MD; Toscano Novella, A, 2010)
"Rib fractures are common in trauma admissions and are associated with an increased risk of pulmonary complications, intensive care unit admissions, and mortality."	( Berry, S; Dalton, A; De Ruyter, M; Howard, J; McDonald, T; Moncure, M; Nazir, N; Shelley, CL; Thepthepha, M, 2016)
"Rib fractures are a common complication caused by chest compressions during resuscitation."	( Hoogendoorn, JM; Pouwels, NSA; van Embden, D, 2018)
"Rib fractures are associated with increased mortality, particularly in the elderly."	( Boyle, K; Carver, TW; Drescher, KM; Juul, J; Kugler, NW; Paul, JS; Peppard, WJ; Rein, L; Somberg, LB; Szabo, A, 2019)
"Rib fractures are a common reason for hospital admission and are associated with significant morbidity and mortality."	( Carty, S; Everson, M; Jeffery, Z, 2019)
"Rib fractures are common among trauma patients and analgesia remains the cornerstone of treatment."	( Davis, JW; Dirks, RC; Kwok, AM; Pang, AW; Sheets, NW; Sue, LP; Wolfe, MM, 2020)
"Rib fractures are painful injuries that are treated with aggressive analgesia, which can include opioids."	( Andriotti, T; Chaudhary, MA; Dalton, MK; Goralnick, E; Jarman, MP; Learn, PA; Sturgeon, D; Weissman, JS, 2020)
"Rib fractures are common injuries among traumatically injured patients, and elderly patients with rib fractures are at increased risk for adverse events and death."	( Antill, AC; Bollig, RW; Daley, BJ; Ford, BR; Frye, SW; Haynes, JC; McMillen, JC, 2020)
"Rib fractures are common in trauma patients and are associated with significant morbidity and mortality."	( Bandy, V; Burton, SW; Gesin, G; Lauer, CW; Riojas, C; Roomian, T; Sing, R; Smith, CB; Wally, MK, 2022)

Excerpt	Reference
"Pain from multiple rib fractures may affect pulmonary function, morbidity, and length of stay in the intensive care units."	( Abadir, AR; Bakalova, T; Govindarajan, R; Michael, R, 2002)

Excerpt	Reference
"Patients after initial operative treatment of rib fractures were excluded."	( de Jong, MB; de Steenwinkel, M; Hietbrink, F; Houwert, RM; Leenen, LPH; van Heerde, S, 2018)

Timeframe	Studies, This Condition (%)	All Conditions %
pre-1990	134 (38.62)	23.3326
1990's	38 (10.95)	12.5806
2000's	53 (15.27)	18.1394
2010's	80 (23.05)	28.8240
2020's	42 (12.10)	9.53

Drug	Relationship Strength	Studies	Trials
carbon monoxide	low	1	0
chlorine	low	1	0
lactic acid	low	2	0
hydrogen carbonate	low	3	0
dalteparin	low	1	0
dihydroxyphenylalanine	low	1	0
methanol	low	1	0
nickel	low	1	0
niacinamide	low	1	0
niacin	low	1	0
1-anilino-8-naphthalenesulfonate	low	1	0
hydroxyindoleacetic acid	low	1	0
acetaminophen	medium	2	2
alendronate	low	3	0
aspirin	low	1	0
azathioprine	low	1	0
benzocaine	low	2	0
clonidine	low	1	0
deferoxamine	low	2	0
pentetic acid	low	1	0
erythrosine	low	1	0
etidronate	low	2	0
fentanyl	medium	7	2
furosemide	low	2	0
gabapentin	medium	1	1
halothane	low	1	0
ibuprofen	medium	2	1
iohexol	low	1	0
ketorolac	medium	2	1
lorazepam	low	1	0
meperidine	medium	3	1
methocarbamol	low	2	0
apnea	low	5	0
nitroglycerin	low	1	0
ofloxacin	low	1	0
oxybutynin	medium	3	1
pamidronate	low	1	0
prazosin	low	1	0
procainamide	low	1	0
procaine	low	6	0
propofol	low	1	0
risperidone	low	1	0
risedronic acid	low	1	0
succinylcholine	low	1	0
terbutaline	low	1	0
tetracaine	medium	1	1
ticlopidine	low	1	0
prednisolone	low	1	0
prednisone	low	3	0
metaraminol	low	1	0
cyanides	low	1	0
bromodeoxyuridine	low	1	0
phenylephrine	low	1	0
edetic acid	low	1	0
methylene blue	low	1	0
oxacillin	low	1	0
histidine	low	1	0
phencyclidine	low	1	0
isoprene	low	1	0
methylprednisolone	low	4	0
cyclohexanol	low	1	0
catechin	medium	1	1
pirinitramide	low	1	0
aminophylline	low	1	0
limestone	low	1	0
phenoperidine	low	1	0
c.i. 42510	low	1	0
deoxycytidine	low	1	0
durapatite	low	2	0
digoxigenin	low	1	0
stavudine	low	1	0
technetium	low	19	0
titanium	medium	16	1
gadolinium	low	1	0
xenon	low	2	0
barium sulfate	low	1	0
calcium sulfate	low	1	0
fluorine	low	1	0
trolamine salicylate	low	2	0
fludrocortisone	low	1	0
4-methoxyamphetamine	low	1	0
transferrin	low	1	0
tramadol	medium	3	2
etofenamate	medium	1	1
propiconazole	low	2	0
atracurium	low	1	0
alfentanil	low	1	0
fluorodopa f 18	low	1	0
gemcitabine	low	1	0
remifentanil	low	1	0
lamivudine	low	1	0
cisatracurium	low	1	0
3-methylhistidine	low	1	0
epigallocatechin gallate	medium	1	1
fluorexon	low	1	0
iobitridol	low	1	0
xenon radioisotopes	low	1	0
delphinidin	low	1	0
fluorodeoxyglucose f18	low	4	0
sertraline	low	1	0
voriconazole	low	1	0
levobupivacaine	low	1	0
methotrexate	low	1	0
levofloxacin	low	1	0
naproxen	medium	1	1
olmesartan	low	1	0
indium trichloride	low	1	0
technetium tc 99m pentetate	low	1	0
angiotensin ii	low	1	0
atropine	low	1	0
dabigatran	low	1	0
cortisone	low	3	0
trimethoprim, sulfamethoxazole drug combination	low	1	0
carboplatin	low	1	0
fibrin	low	1	0
inositol 3-phosphate	low	1	0
pentazocine	low	1	0
melphalan	low	1	0
buprenorphine	medium	2	1
pyrophosphate	low	2	0
digoxin	low	1	0
nitinol	low	1	0
17-ketosteroids	low	3	0
osteoprotegerin	low	1	0
bilirubin	low	1	0
dinoprostone	low	3	0
vitamin k semiquinone radical	low	1	0
alprostadil	low	1	0
vitamin d 2	low	2	0
cholecalciferol	low	1	0
phenylephrine hydrochloride	low	3	0
naloxone	low	1	0
lead	low	1	0
antimony	low	1	0
aluminum	low	3	0
indium	low	2	0
indinavir sulfate	low	1	0
sulfur	low	1	0
enalapril	low	1	0
phosphorus	low	4	0
abt-100	low	1	0
technetium tc 99m pyrophosphate	low	2	0
technetium tc 99m diphosphonate	low	2	0
aluminum oxide	low	3	0
acid phosphatase	low	1	0
phosphatidylcholines	low	1	0
ro13-9904	low	1	0
piperidines	low	1	0
acenocoumarol	low	1	0
warfarin	low	2	0
phenprocoumon	low	1	0
transforming growth factor beta	low	2	0
mulundocandin	low	1	0
technetium tc 99m medronate	low	15	0
exudates	low	1	0
guanine	low	1	0
ganciclovir	low	1	0
pemetrexed	low	1	0
pyrimidinones	low	1	0

Protein Targets (1,091)

Protein	Potency Measurements	Inhibition Measurements	Activation Measurements	Drugs
Chain B, pheromone binding protein	0	0	1	1
Chain A, pheromone binding protein	0	0	1	1
Chain A, JmjC domain-containing histone demethylation protein 3A	9	0	0	9
Chain A, RNA-directed RNA polymerase NS5	0	1	0	1
acid sphingomyelinase	4	0	0	4
thioredoxin reductase	24	0	0	24
USP1 protein, partial	17	0	0	17
TDP1 protein	37	0	0	37
vitamin D3 receptor isoform VDRA	12	0	0	12
importin subunit beta-1 isoform 1	4	0	0	4
flap endonuclease 1	12	0	0	12
serine/threonine-protein kinase PLK1	1	0	0	1
snurportin-1	4	0	0	4
peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	4	0	0	4
GTP-binding nuclear protein Ran isoform 1	1	0	0	1
DNA polymerase eta isoform 1	4	0	0	4
DNA polymerase iota isoform a (long)	13	0	0	13
urokinase-type plasminogen activator precursor	7	0	0	7
plasminogen precursor	7	0	0	7
urokinase plasminogen activator surface receptor precursor	7	0	0	7
geminin	33	0	0	33
DNA polymerase kappa isoform 1	12	0	0	12
fibroblast growth factor 22 isoform 1 precursor	0	0	0	1
Mitogen-activated protein kinase 13	0	1	0	1
Beta-lactamase	0	1	0	1
Transthyretin	0	0	2	2
Fatty acid-binding protein, intestinal	0	3	2	5
Fatty acid-binding protein, adipocyte	0	1	1	2
Cyclin-A2	0	1	0	1
Cannabinoid receptor 1	0	0	1	1
Cyclin-dependent kinase 2	0	1	2	3
Choline O-acetyltransferase	0	1	0	1
Mitogen-activated protein kinase 12	0	1	0	1
Guanine nucleotide-binding protein G	5	0	0	5
Fatty acid-binding protein 5	0	0	1	1
Fatty acid-binding protein 5	0	0	1	1
Mitogen-activated protein kinase 11	0	1	0	1
Mitogen-activated protein kinase 14	0	2	0	2
5-hydroxytryptamine receptor 2C	0	6	1	8
5-hydroxytryptamine receptor 2A	0	5	1	6
5-hydroxytryptamine receptor 1A	0	6	1	7
5-hydroxytryptamine receptor 1B	0	6	1	7
5-hydroxytryptamine receptor 1D	0	2	1	3
5-hydroxytryptamine receptor 1F	0	2	1	3
5-hydroxytryptamine receptor 2B	0	4	1	5
5-hydroxytryptamine receptor 6	0	0	1	1
Sodium-dependent serotonin transporter	0	3	2	5
Sodium-dependent serotonin transporter	0	5	0	5
5-hydroxytryptamine receptor 7	0	1	1	2
5-hydroxytryptamine receptor 5A	0	0	1	1
5-hydroxytryptamine receptor 5B	0	0	1	1
5-hydroxytryptamine receptor 3A	0	0	1	1
5-hydroxytryptamine receptor 4	0	0	1	1
5-hydroxytryptamine receptor 3B	0	0	1	1
Ephrin type-A receptor 1	0	0	1	1
Histamine H1 receptor	0	4	0	4
Beta-adrenergic receptor kinase 2	0	0	1	1
Cyclin-dependent kinase 7	0	0	1	1
Calcium/calmodulin-dependent protein kinase type 1B	0	0	1	1
Serine/threonine-protein kinase BRSK2	0	0	1	1
Serine/threonine-protein kinase Nek7	0	0	1	1
Aurora kinase B	0	0	1	1
Homeodomain-interacting protein kinase 2	0	0	1	1
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE	23	0	0	23
Luciferase	9	0	0	9
RAR-related orphan receptor gamma	25	0	0	25
retinoid X nuclear receptor alpha	22	0	0	22
G	16	0	0	16
peroxisome proliferator activated receptor gamma	16	0	0	16
euchromatic histone-lysine N-methyltransferase 2	42	0	0	42
thyroid stimulating hormone receptor	13	0	0	13
chromobox protein homolog 1	18	0	0	18
parathyroid hormone/parathyroid hormone-related peptide receptor precursor	6	0	0	6
muscleblind-like protein 1 isoform 1	6	0	0	6
Interferon beta	22	0	0	22
HLA class I histocompatibility antigen, B alpha chain	16	0	0	16
Inositol hexakisphosphate kinase 1	16	0	0	16
cytochrome P450 2C9, partial	16	0	0	16
ATAD5 protein, partial	16	0	0	16
GLS protein	14	0	0	14
Microtubule-associated protein tau	15	0	0	15
Smad3	9	0	0	9
aldehyde dehydrogenase 1 family, member A1	27	0	0	27
thyroid stimulating hormone receptor	16	0	0	16
nuclear receptor subfamily 1, group I, member 3	21	0	0	21
progesterone receptor	19	0	0	19
EWS/FLI fusion protein	21	0	0	21
retinoic acid nuclear receptor alpha variant 1	26	0	0	26
estrogen-related nuclear receptor alpha	30	0	0	30
estrogen nuclear receptor alpha	47	0	0	47
aryl hydrocarbon receptor	17	0	0	17
thyroid hormone receptor beta isoform 2	23	0	0	23
peripheral myelin protein 22	13	0	0	13
cytochrome P450 3A4 isoform 1	13	0	0	13
Gamma-aminobutyric acid receptor subunit pi	13	2	1	16
ATP-binding cassette sub-family C member 3	0	31	0	31
Multidrug resistance-associated protein 4	0	31	0	34
Solute carrier family 22 member 6	0	5	0	5
Carbonic anhydrase 12	0	2	0	4
UDP-glucuronosyltransferase 1A9	0	0	0	2
Bile salt export pump	0	7	0	7
Voltage-dependent calcium channel gamma-2 subunit	18	0	0	18
Bile salt export pump	0	50	0	50
Cytochrome P450 2B1	0	0	0	1
Cytochrome P450 1A1	0	0	0	1
Carbonic anhydrase 1	0	10	0	13
Carbonic anhydrase 2	0	10	1	14
Myoglobin	0	1	0	1
Cytochrome P450 1A1	0	0	1	2
Cytochrome P450 1A2	0	0	0	1
Prostaglandin G/H synthase 1	0	5	1	6
Carbonic anhydrase 3	0	2	0	3
Cytochrome P450 3A4	0	9	2	12
Cytochrome P450 2D6	0	8	0	8
Cytochrome P450 2C9	0	13	1	14
Polyunsaturated fatty acid lipoxygenase ALOX15	0	2	0	2
Gamma-aminobutyric acid receptor subunit beta-1	13	2	1	16
Sulfotransferase 1A1	0	0	0	1
Gamma-aminobutyric acid receptor subunit delta	13	2	1	16
Gamma-aminobutyric acid receptor subunit gamma-2	13	2	1	16
UDP-glucuronosyltransferase 1-6	0	0	0	1
Glutamate receptor 2	19	0	0	19
Gamma-aminobutyric acid receptor subunit alpha-5	13	2	1	16
Gamma-aminobutyric acid receptor subunit alpha-3	13	2	1	16
Arachidonate 5-lipoxygenase-activating protein	0	1	0	1
UDP-glucuronosyltransferase 1A1	0	0	0	1
Carbonic anhydrase 4	0	6	0	8
Prostaglandin G/H synthase 1	0	8	0	8
Carbonic anhydrase 6	0	3	0	5
Gamma-aminobutyric acid receptor subunit gamma-1	13	2	1	16
Gamma-aminobutyric acid receptor subunit alpha-2	13	2	1	16
Gamma-aminobutyric acid receptor subunit alpha-4	13	2	1	16
Gamma-aminobutyric acid receptor subunit gamma-3	13	2	1	16
Gamma-aminobutyric acid receptor subunit alpha-6	13	2	1	16
Carbonic anhydrase 5A, mitochondrial	0	2	0	4
Prostaglandin G/H synthase 2	0	7	0	8
Carbonic anhydrase 7	0	2	0	4
Nuclear receptor ROR-gamma	9	1	1	11
Cytochrome P450 2J2	0	9	0	9
Gamma-aminobutyric acid receptor subunit alpha-1	13	3	1	17
Gamma-aminobutyric acid receptor subunit beta-3	13	2	1	16
Gamma-aminobutyric acid receptor subunit beta-2	13	2	1	16
Carbonic anhydrase 9	0	2	0	4
GABA theta subunit	13	2	1	16
Canalicular multispecific organic anion transporter 1	0	30	0	30
Carbonic anhydrase 15	0	4	0	5
Carbonic anhydrase 13	0	2	0	4
Gamma-aminobutyric acid receptor subunit epsilon	13	2	1	16
Carbonic anhydrase 14	0	2	0	4
Carbonic anhydrase 5B, mitochondrial	0	2	0	4
toxin B	0	0	0	1
Chain A, farnesyl pyrophosphate synthase	0	1	0	1
Geranylgeranyl pyrophosphate synthase	0	4	0	4
Farnesyl pyrophosphate synthase	0	6	0	6
Acetylcholinesterase	0	6	0	6
Hypoxanthine-guanine phosphoribosyltransferase	0	2	0	2
Farnesyl pyrophosphate synthase	0	4	0	4
Farnesyl pyrophosphate synthase	0	2	0	2
ATP-dependent translocase ABCB1	0	7	0	11
Mu-type opioid receptor	0	11	4	18
Kappa-type opioid receptor	0	8	1	9
Mu-type opioid receptor	0	10	1	11
Sigma non-opioid intracellular receptor 1	0	7	0	7
AR protein	42	0	0	42
glucocorticoid receptor [Homo sapiens]	29	0	0	29
Cellular tumor antigen p53	23	0	0	23
Thromboxane-A synthase	0	2	0	2
Prostaglandin E2 receptor EP3 subtype	0	2	0	2
Prostaglandin E2 receptor EP4 subtype	0	2	1	3
Prostaglandin E2 receptor EP1 subtype	0	2	0	2
Prostacyclin receptor	0	3	2	5
Nuclear receptor subfamily 4 group A member 2	0	0	1	1
Solute carrier organic anion transporter family member 2A1	0	1	0	3
Nuclear receptor subfamily 4 group A member 2	0	0	1	1
Nuclear receptor subfamily 4 group A member 2	0	0	1	1
Prostaglandin E2 receptor EP2 subtype	0	2	1	3
Solute carrier organic anion transporter family member 2A1	0	0	0	2
Solute carrier organic anion transporter family member 2B1	0	1	0	1
Solute carrier organic anion transporter family member 3A1	0	0	0	1
Chain U, UROKINASE-TYPE PLASMINOGEN ACTIVATOR	0	1	0	1
Chain A, UROKINASE-TYPE PLASMINOGEN ACTIVATOR	0	1	0	1
Chain A, UROKINASE-TYPE PLASMINOGEN ACTIVATOR	0	1	0	1
Chain A, HADH2 protein	13	0	0	13
Chain B, HADH2 protein	13	0	0	13
Chain A, 2-oxoglutarate Oxygenase	15	0	0	15
acetylcholinesterase	12	0	0	12
regulator of G-protein signaling 4	10	0	0	10
glucocerebrosidase	5	0	0	5
arylsulfatase A	13	0	0	13
alpha-galactosidase	5	0	0	5
Bloom syndrome protein isoform 1	15	0	0	15
cytochrome P450 2D6 isoform 1	6	0	0	6
lysosomal alpha-glucosidase preproprotein	5	0	0	5
cytochrome P450 2C19 precursor	7	0	0	7
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1	10	0	0	10
huntingtin isoform 2	2	0	0	2
nuclear factor erythroid 2-related factor 2 isoform 1	25	0	0	25
lamin isoform A-delta10	31	0	0	31
Membrane primary amine oxidase	0	2	0	2
Solute carrier family 22 member 1	0	11	0	15
Prothrombin	0	4	1	5
Coagulation factor X	0	2	0	2
Plasminogen	0	2	0	2
Urokinase-type plasminogen activator	0	3	0	3
Tissue-type plasminogen activator	0	4	0	4
Cationic trypsin	0	1	0	1
Coagulation factor XI	0	1	0	1
Plasma kallikrein	0	1	0	2
Vitamin K-dependent protein C	0	2	0	2
Urokinase-type plasminogen activator	0	3	0	3
Trypsin-1	0	2	0	2
Trypsin-2	0	2	0	2
Sodium/hydrogen exchanger 1	0	1	0	1
Amine oxidase [flavin-containing] A	0	5	0	5
Sodium/hydrogen exchanger 1	0	2	0	2
Sodium/hydrogen exchanger 3	0	2	0	2
Adenosine receptor A2a	0	1	0	1
Trypsin-3	0	2	0	2
Amiloride-sensitive sodium channel subunit alpha	0	1	0	1
5-hydroxytryptamine receptor 7	0	5	0	5
Sodium/hydrogen exchanger 2	0	2	0	2
Acid-sensing ion channel 1	0	2	0	2
Potassium voltage-gated channel subfamily H member 2	0	17	0	17
Sodium channel protein type 5 subunit alpha	0	4	0	4
Sodium/hydrogen exchanger 5	0	2	0	2
Solute carrier family 22 member 1	0	5	0	5
Solute carrier family 22 member 2	0	3	0	3
Acid-sensing ion channel 3	0	1	0	1
Sodium/hydrogen exchanger	0	1	0	1
histone acetyltransferase KAT2A isoform 1	15	0	0	15
Atrial natriuretic peptide receptor 3	0	1	0	1
Type-1A angiotensin II receptor	0	2	1	3
Type-1 angiotensin II receptor	0	0	1	1
Type-1B angiotensin II receptor	0	2	0	2
Type-1 angiotensin II receptor	0	2	2	4
Type-2 angiotensin II receptor	0	3	0	3
Type-2 angiotensin II receptor	0	2	0	2
D(1A) dopamine receptor	6	0	0	6
neuropeptide S receptor isoform A	4	0	0	4
Chain A, TYROSYL-DNA PHOSPHODIESTERASE	13	0	0	13
Chain A, Phospholipase A2 isoform 3	0	0	1	1
GTP-binding protein (rab7)	0	0	1	1
ras protein, partial	0	0	1	1
interleukin 8	7	0	0	7
hypothetical protein, conserved	4	0	0	4
cytochrome P450 family 3 subfamily A polypeptide 4	20	0	0	20
cytochrome P450 2D6	14	0	0	14
peroxisome proliferator-activated receptor delta	11	0	0	11
Rac1 protein	0	0	1	1
IDH1	15	0	0	15
cell division cycle 42 (GTP binding protein, 25kDa), partial	0	0	1	1
muscarinic acetylcholine receptor M1	14	0	0	14
lethal factor (plasmid)	3	0	0	3
Prostaglandin-H2 D-isomerase	0	1	0	1
Prostaglandin G/H synthase 1	0	4	0	4
Prostaglandin G/H synthase 2	0	2	0	2
Epidermal growth factor receptor	0	4	0	4
Fatty acid-binding protein, liver	0	5	0	5
Integrin beta-3	5	1	0	6
Myeloperoxidase	0	1	0	1
Seed linoleate 13S-lipoxygenase-1	0	1	0	1
Integrin alpha-IIb	5	1	0	6
Glutathione hydrolase 1 proenzyme	0	1	0	1
Adenosine receptor A1	1	4	0	6
Adenosine receptor A2a	0	4	1	6
Substance-P receptor	0	2	0	2
Urotensin-2 receptor	0	1	0	1
4-aminobutyrate aminotransferase, mitochondrial	0	2	0	2
Ras-related protein Rab-2A	0	0	1	1
Prostaglandin G/H synthase 2	0	5	0	5
Rho-associated protein kinase 2	0	1	0	1
Nicotinate phosphoribosyltransferase	0	1	0	1
Solute carrier family 22 member 20	0	4	0	4
Solute carrier family 22 member 6	0	4	0	4
Sigma non-opioid intracellular receptor 1	0	14	1	15
Sigma non-opioid intracellular receptor 1	0	5	1	6
NPYLR7B	0	0	1	1
Amine oxidase [flavin-containing] A	0	0	1	1
Small conductance calcium-activated potassium channel protein 3	0	1	1	2
GLI family zinc finger 3	24	0	0	24
pregnane X nuclear receptor	21	0	0	21
cystic fibrosis transmembrane conductance regulator	0	1	0	1
DNA polymerase beta	7	0	0	7
short transient receptor potential channel 6 isoform 1	0	0	1	1
5-hydroxytryptamine receptor 4	0	10	0	10
Muscarinic acetylcholine receptor M2	0	7	2	13
Muscarinic acetylcholine receptor M4	0	7	1	10
Muscarinic acetylcholine receptor M1	0	6	2	10
Muscarinic acetylcholine receptor M3	0	5	2	9
Muscarinic acetylcholine receptor M4	0	4	2	8
Muscarinic acetylcholine receptor M5	0	4	2	8
Muscarinic acetylcholine receptor M5	0	7	1	10
Muscarinic acetylcholine receptor M2	0	5	2	10
Muscarinic acetylcholine receptor M1	0	7	1	12
Muscarinic acetylcholine receptor M1	0	0	1	3
Muscarinic acetylcholine receptor M3	0	6	1	9
Alpha-1D adrenergic receptor	0	8	2	12
5-hydroxytryptamine receptor 2C	0	10	0	10
Muscarinic acetylcholine receptor M4	0	1	1	3
Histamine H2 receptor	7	0	0	8
Reverse transcriptase/RNaseH	0	2	3	7
Muscarinic acetylcholine receptor	0	1	2	3
Chain A, Ferritin light chain	10	0	0	10
phosphopantetheinyl transferase	10	0	0	10
SMAD family member 2	8	0	0	8
Fumarate hydratase	9	0	0	9
SMAD family member 3	8	0	0	8
thioredoxin glutathione reductase	10	0	0	10
farnesoid X nuclear receptor	16	0	0	16
polyprotein	9	0	0	9
P53	1	0	0	1
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a	16	0	0	16
activating transcription factor 6	8	0	0	8
v-jun sarcoma virus 17 oncogene homolog (avian)	13	0	0	13
Histone H2A.x	10	0	0	10
peripheral myelin protein 22 isoform 1	6	0	0	6
hemoglobin subunit beta	1	0	0	1
cellular tumor antigen p53 isoform a	7	0	0	7
heat shock protein beta-1	6	0	0	6
survival motor neuron protein isoform d	12	0	0	12
M-phase phosphoprotein 8	5	0	0	5
ATPase family AAA domain-containing protein 5	14	0	0	14
Ataxin-2	16	0	0	16
Protein-arginine deiminase type-4	0	2	0	2
glp-1 receptor, partial	12	0	0	12
nuclear receptor ROR-gamma isoform 1	6	0	0	6
TAR DNA-binding protein 43	8	0	0	8
Chain A, Putative fructose-1,6-bisphosphate aldolase	8	0	0	8
Chain A, Cruzipain	7	0	0	7
caspase-1 isoform alpha precursor	2	0	0	2
Caspase-7	3	0	0	3
Inositol monophosphatase 1	4	0	0	4
Solute carrier organic anion transporter family member 1B3	0	3	0	6
Solute carrier organic anion transporter family member 1B1	0	3	0	5
pregnane X receptor	4	0	0	4
bromodomain adjacent to zinc finger domain 2B	6	0	0	6
nuclear receptor subfamily 1, group I, member 2	5	0	0	5
Nuclear hormone receptor family member daf-12	0	0	1	1
nuclear factor erythroid 2-related factor 2 isoform 2	11	0	0	11
serine/threonine-protein kinase mTOR isoform 1	3	0	0	3
oxysterols receptor LXR-beta isoform 1	0	0	1	1
Thymidine kinase, cytosolic	0	2	0	3
Thymidine phosphorylase	0	0	0	1
Thymidylate kinase	0	1	0	1
Spike glycoprotein	16	0	1	17
Thymidine kinase	0	0	0	1
Thymidylate kinase	0	1	0	1
Potassium channel subfamily K member 3	0	4	0	4
Potassium channel subfamily K member 3	0	1	0	1
Potassium channel subfamily K member 2	0	1	1	2
Potassium channel subfamily K member 9	0	1	0	1
Kappa-type opioid receptor	0	10	3	16
estrogen receptor 2 (ER beta)	12	0	0	12
histone-lysine N-methyltransferase 2A isoform 2 precursor	3	0	0	3
ATP-dependent phosphofructokinase	11	0	0	11
Chain A, ATP-DEPENDENT DNA HELICASE Q1	6	0	0	6
Arginase	0	2	0	2
Pancreatic triacylglycerol lipase	0	1	0	1
Aldo-keto reductase family 1 member B1	0	7	0	7
Sucrase-isomaltase, intestinal	0	1	0	1
Mu-type opioid receptor	0	9	5	17
Delta-type opioid receptor	0	8	2	13
Xanthine dehydrogenase/oxidase	0	2	0	2
Melatonin receptor type 1A	0	0	1	1
Melatonin receptor type 1B	0	0	1	1
Death-associated protein kinase 1	0	1	0	1
Beta-secretase 1	0	2	0	2
Carbonic anhydrase 3	0	1	0	1
Dihydroorotate dehydrogenase	0	1	0	1
Carbonic anhydrase	0	4	0	5
15-lipoxygenase, partial	5	0	0	5
vitamin D (1,25- dihydroxyvitamin D3) receptor	13	0	0	13
thyroid hormone receptor beta isoform a	8	0	0	8
60 kDa chaperonin	0	3	0	3
60 kDa heat shock protein, mitochondrial	0	3	0	3
Vitamin D3 receptor	0	1	1	5
Glycine receptor subunit alpha-1	0	0	2	2
Vitamin D3 receptor	0	0	1	1
10 kDa heat shock protein, mitochondrial	0	3	0	3
Thiosulfate sulfurtransferase	0	3	0	3
60 kDa chaperonin	0	3	0	3
10 kDa chaperonin	0	3	0	3
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	9	0	0	9
Beta-1 adrenergic receptor	0	0	1	1
Alpha-1B adrenergic receptor	0	0	2	2
cytochrome P450 2C9 precursor	4	0	0	4
5-hydroxytryptamine receptor 3A	0	0	1	1
Solute carrier family 22 member 3	0	5	0	5
5-hydroxytryptamine receptor 1A	0	3	2	5
Alpha-2A adrenergic receptor	0	11	3	15
Alpha-1B adrenergic receptor	0	7	1	8
Alpha-2B adrenergic receptor	0	11	1	13
Alpha-1A adrenergic receptor	0	2	2	4
Alpha-2C adrenergic receptor	0	11	2	14
D	0	4	0	4
D(3) dopamine receptor	0	4	0	4
Alpha-2B adrenergic receptor	0	5	1	6
Alpha-2C adrenergic receptor	0	5	1	6
Alpha-2A adrenergic receptor	0	5	1	6
Alpha-1D adrenergic receptor	0	7	1	8
D(1B) dopamine receptor	0	2	0	2
Amine oxidase [flavin-containing] B	0	2	0	2
Adenosine receptor A2b	0	0	1	1
Alpha-2B adrenergic receptor	0	1	0	3
D(4) dopamine receptor	0	2	0	2
Delta-type opioid receptor	0	7	1	11
Alpha-1A adrenergic receptor	0	6	3	13
Alpha-1B adrenergic receptor	0	5	3	10
Alpha-1A adrenergic receptor	0	7	2	9
D(2) dopamine receptor	0	6	0	6
Alpha-2C adrenergic receptor	0	1	0	3
Alpha-2A adrenergic receptor	0	1	0	3
Alpha-2A adrenergic receptor	0	2	0	2
Nischarin	0	2	0	2
Multidrug and toxin extrusion protein 1	0	11	0	11
Nischarin	0	1	0	1
endonuclease IV	7	0	0	7
dopamine D1 receptor	3	0	0	3
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a	8	0	0	8
atrial natriuretic peptide receptor 1 precursor	1	0	0	1
Glucocorticoid receptor	0	8	2	15
Sex hormone-binding globulin	0	0	1	1
Glycine receptor subunit alpha-1	0	8	0	8
Corticosteroid-binding globulin	0	2	0	2
Glycine receptor subunit beta	0	8	0	8
Glycine receptor subunit alpha-2	0	8	0	8
Glycine receptor subunit alpha-3	0	8	0	8
Potassium voltage-gated channel subfamily A member 1	0	0	1	1
Solute carrier family 22 member 2	0	5	0	6
Coagulation factor XII	0	1	0	1
Serine protease hepsin	0	1	0	1
Ribosyldihydronicotinamide dehydrogenase [quinone]	0	3	0	3
Multidrug and toxin extrusion protein 2	0	4	0	4
apical membrane antigen 1, AMA1	2	0	0	2
67.9K protein	7	0	0	7
Lysine-specific demethylase 4A	0	1	0	1
Hypoxia-inducible factor 1-alpha	0	0	1	1
Methylcytosine dioxygenase TET2	0	1	0	1
Deoxyhypusine hydroxylase	0	1	0	1
Vascular endothelial growth factor receptor 2	0	1	0	1
Alpha-synuclein	1	1	0	2
Lactoylglutathione lyase	0	1	0	1
Histone acetyltransferase p300	0	2	0	2
CREB-binding protein	0	2	0	2
Thymidine kinase 2	0	2	0	2
Deoxycytidine kinase	0	0	0	2
Probable deoxycytidylate deaminase	0	0	0	1
Cytidine deaminase	0	0	0	2
AAA family ATPase	0	0	0	2
Chain A, DigA16	0	0	1	1
Chain A, DigA16	0	0	1	1
PAX8	0	0	0	2
NPC intracellular cholesterol transporter 1 precursor	5	0	0	5
ras-related protein Rab-9A	6	0	0	6
Sodium/potassium-transporting ATPase subunit alpha-1	0	3	0	3
Sodium/potassium-transporting ATPase subunit beta-1	0	3	0	3
Sodium/potassium-transporting ATPase subunit alpha-2	0	3	0	3
Solute carrier organic anion transporter family member 4C1	0	1	0	2
Rap guanine nucleotide exchange factor 4	1	0	0	1
Chain A, Beta-lactamase	9	0	0	9
PPM1D protein	5	0	0	5
STAT3, partial	0	1	0	1
tumor necrosis factor	1	0	0	1
signal transducer and activator of transcription 1-alpha/beta isoform alpha	0	1	0	1
Solute carrier organic anion transporter family member 1A4	0	2	0	3
Sodium/potassium-transporting ATPase subunit alpha-2	0	1	0	1
Sodium/potassium-transporting ATPase subunit alpha-3	0	1	0	1
ATP-dependent translocase ABCB1	0	2	0	2
Sodium/potassium-transporting ATPase subunit beta-1	0	1	0	1
Replicase polyprotein 1ab	0	3	1	4
Sodium/potassium-transporting ATPase subunit alpha-3	0	1	0	1
Sodium/potassium-transporting ATPase subunit beta-2	0	1	0	1
ATP-dependent translocase ABCB1	0	2	0	2
Sodium/potassium-transporting ATPase subunit alpha-1	0	1	0	1
Sodium/potassium-transporting ATPase subunit beta-3	0	1	0	1
Sodium/potassium-transporting ATPase subunit gamma	0	1	0	1
Sodium/potassium-transporting ATPase subunit alpha-4	0	1	0	1
Sodium/potassium-transporting ATPase subunit alpha-4	0	1	0	1
Solute carrier organic anion transporter family member 4C1	0	0	0	1
Solute carrier organic anion transporter family member 1A4	0	0	0	1
polyunsaturated fatty acid lipoxygenase ALOX12	2	0	0	2
runt-related transcription factor 1 isoform AML1b	1	0	0	1
core-binding factor subunit beta isoform 2	1	0	0	1
mitogen-activated protein kinase 1	8	0	0	8
Glutamate receptor 1	1	0	0	1
Glutamate receptor 3	1	0	0	1
Glutamate receptor 4	1	0	0	1
prostaglandin E2 receptor EP2 subtype	1	0	0	1
Solute carrier organic anion transporter family member 1A5	0	0	0	1
Prostaglandin E2 receptor EP1 subtype	0	2	1	3
Prostaglandin E2 receptor EP4 subtype	0	2	1	3
Prostaglandin F2-alpha receptor	0	0	1	1
Prostaglandin E2 receptor EP4 subtype	0	1	1	2
Prostaglandin E2 receptor EP3 subtype	0	2	1	3
Prostaglandin E2 receptor EP2 subtype	0	2	1	3
Solute carrier family 22 member 6	0	2	0	5
Solute carrier family 22 member 7	0	0	0	1
Prostaglandin E2 receptor EP2 subtype	0	1	1	2
Solute carrier family 22 member 8	0	1	0	3
Solute carrier family 22 member 7	0	0	0	1
Solute carrier family 22 member 11	0	0	0	2
Solute carrier organic anion transporter family member 1B2	0	0	0	1
Solute carrier family 22 member 7	0	0	0	1
hypoxia-inducible factor 1 alpha subunit	5	0	0	5
Eyes absent homolog 2	0	1	0	1
Polyunsaturated fatty acid lipoxygenase ALOX15B	4	0	0	4
Amyloid-beta precursor protein	0	5	0	5
Angiotensin-converting enzyme	0	2	0	2
Metallo-beta-lactamase VIM-13	0	1	0	1
Beta-lactamase	0	1	0	1
Beta-lactamase	0	1	0	1
Beta-lactamase VIM-1	0	1	0	1
Angiotensin-converting enzyme	0	7	0	7
Succinyl-diaminopimelate desuccinylase	0	1	0	1
Solute carrier family 15 member 1	0	2	0	2
Solute carrier organic anion transporter family member 1A1	0	1	0	2
Angiotensin-converting enzyme	0	1	0	1
Solute carrier family 15 member 1	0	1	0	1
Angiotensin-converting enzyme 2	0	1	1	2
Chain A, Troponin C, slow skeletal and cardiac muscles	0	0	1	1
Chain A, Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	0	0	1	1
Chain A, POLYMERASE PA	0	1	0	1
Chain A, Polymerase Pa	0	1	0	1
Chain A, Polymerase Pa	0	1	0	1
Chain A, Polymerase Pa	0	1	0	1
Chain A, Polymerase Pa	0	1	0	1
Genome polyprotein	0	2	1	3
Replicase polyprotein 1ab	0	2	1	3
galactokinase	1	0	0	1
pyruvate kinase PKM isoform a	2	0	0	2
nuclear factor NF-kappa-B p105 subunit isoform 1	1	0	0	1
POsterior Segregation	0	0	2	2
Prostaglandin E synthase	0	1	0	1
Telomerase reverse transcriptase	0	1	0	1
Polycomb protein EED	0	0	1	1
NAD kinase	0	2	1	3
Dihydrofolate reductase	0	6	0	8
Polymerase acidic protein	0	1	0	1
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1	0	1	0	1
Plasminogen activator inhibitor 1	0	1	0	1
Heme oxygenase 1	0	1	0	1
Heat shock protein HSP 90-beta	0	1	0	1
Neutrophil elastase	0	1	0	1
72 kDa type IV collagenase	0	1	0	1
Hepatocyte growth factor receptor	0	2	0	2
Matrilysin	0	1	0	1
Enoyl-[acyl-carrier-protein] reductase [NADH] FabI	0	1	0	1
Alpha-amylase 1A	0	1	0	1
Apoptosis regulator Bcl-2	0	2	0	2
Microtubule-associated protein tau	0	2	1	3
Glucose-6-phosphate 1-dehydrogenase	0	1	0	1
Fatty acid synthase	0	1	0	1
CPG DNA methylase	0	1	0	1
Lethal factor	0	1	0	1
Phosphoglycerate mutase 1	0	1	0	1
Cannabinoid receptor 1	0	1	0	1
Heme oxygenase 2	0	1	0	1
Sodium-dependent noradrenaline transporter	0	6	3	9
DNA (cytosine-5)-methyltransferase 1	0	2	0	2
Dipeptidyl peptidase 4	0	1	0	1
Proteasome subunit beta type-5	0	1	0	1
Cannabinoid receptor 2	0	1	0	1
Signal transducer and activator of transcription 1-alpha/beta	0	0	1	1
DNA repair protein RAD52 homolog	0	1	0	1
Fatty acid synthase	0	1	0	1
Matrix metalloproteinase-14	0	1	0	1
4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase FUT6	0	1	0	1
Squalene monooxygenase	0	1	0	1
6-phosphogluconate dehydrogenase, decarboxylating	0	3	0	3
BH3-interacting domain death agonist	0	1	0	1
Disintegrin and metalloproteinase domain-containing protein 17	1	1	0	2
Lactoperoxidase	0	0	0	1
Bcl-2-like protein 1	0	1	0	1
Induced myeloid leukemia cell differentiation protein Mcl-1	0	1	0	1
Alpha-(1,3)-fucosyltransferase 7	0	1	0	1
CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1	0	1	0	1
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	0	1	0	1
Dual specificity tyrosine-phosphorylation-regulated kinase 1A	0	1	0	1
Bcl-2-related protein A1	0	1	0	1
Dual specificity tyrosine-phosphorylation-regulated kinase 1A	0	1	0	1
3-oxoacyl-[acyl-carrier-protein] reductase	0	1	0	1
MAP kinase-activated protein kinase 5	0	1	0	1
Histone acetyltransferase KAT2B	0	1	0	1
Bcl-2-like protein 2	0	1	0	1
Bcl2-associated agonist of cell death	0	1	0	1
Histone acetyltransferase KAT5	0	1	0	1
Enoyl-acyl-carrier protein reductase	0	2	0	2
3-oxoacyl-acyl-carrier protein reductase	0	1	0	1
Beta-hydroxyacyl-ACP dehydratase precursor (Fatty acid synthesis protein)	0	1	0	1
Bcl-2-like protein 10	0	1	0	1
Zinc finger protein mex-5	0	0	2	2
chaperonin-containing TCP-1 beta subunit homolog	2	0	0	2
thyrotropin-releasing hormone receptor	3	0	0	3
ubiquitin carboxyl-terminal hydrolase 2 isoform a	3	0	0	3
eyes absent homolog 2 isoform a	2	0	0	2
lethal(3)malignant brain tumor-like protein 1 isoform I	1	0	0	1
relaxin receptor 1 isoform 1	1	0	0	1
Flavin reductase (NADPH)	0	0	1	1
large T antigen	0	1	0	1
Type IV secretion-like conjugative transfer relaxase protein TraI	0	1	0	1
potassium voltage-gated channel subfamily H member 2 isoform d	6	0	0	6
Nuclear receptor subfamily 1 group I member 2	0	0	2	2
D(2) dopamine receptor	0	3	0	3
D(4) dopamine receptor	0	3	0	3
Delta-type opioid receptor	0	8	3	12
Kappa-type opioid receptor	0	5	3	9
D(3) dopamine receptor	0	6	0	6
Mu-type opioid receptor	0	5	1	10
GALC protein	3	0	0	3
Multidrug resistance-associated protein 1	0	0	0	2
Albumin	0	4	5	11
Glucose-6-phosphate 1-dehydrogenase	0	2	0	2
Serum paraoxonase/arylesterase 1	0	1	0	1
Corticosteroid 11-beta-dehydrogenase isozyme 1	0	1	0	1
Adenosine receptor A1	0	1	0	1
Corticosteroid 11-beta-dehydrogenase isozyme 1	0	1	0	1
Holo-[acyl-carrier-protein] synthase	0	1	0	1
Sodium/bile acid cotransporter	0	1	0	1
G-protein coupled receptor 35	0	1	1	2
CDGSH iron-sulfur domain-containing protein 1	0	2	0	2
Broad substrate specificity ATP-binding cassette transporter ABCG2	0	1	0	3
Voltage-dependent calcium channel subunit alpha-2/delta-1	0	1	0	1
Thymidine kinase	0	1	0	1
ClpP	2	0	0	2
NFKB1 protein, partial	4	0	0	4
POU domain, class 2, transcription factor 2	0	0	0	1
Transitional endoplasmic reticulum ATPase	0	1	0	1
Purine nucleoside phosphorylase	0	0	1	1
Chain A, DEOXYNUCLEOSIDE KINASE	0	1	0	1
Spike glycoprotein	0	0	1	1
Transmembrane protease serine 2	0	0	1	1
Procathepsin L	0	0	1	1
Replicase polyprotein 1a	0	0	1	1
Replicase polyprotein 1ab	0	0	1	1
Replicase polyprotein 1ab	0	1	1	2
Equilibrative nucleoside transporter 1	0	1	0	1
Purine nucleoside phosphorylase	0	2	0	2
Hypoxanthine-guanine phosphoribosyltransferase	0	0	0	1
Ricin	0	1	0	1
2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase	0	0	1	1
Purine nucleoside phosphorylase	0	0	1	2
Shiga toxin subunit A	0	1	0	1
Guanine deaminase	0	0	0	1
Voltage-dependent L-type calcium channel subunit alpha-1C	0	5	0	5
Chain A, HISTIDINE-BINDING PROTEIN	0	0	1	1
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	1	1
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	1	1
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	1	1
Histidine-binding periplasmic protein	0	0	1	1
5-hydroxytryptamine receptor 1D	0	1	0	2
Glutamate receptor ionotropic, NMDA 1	0	4	0	5
Carbonic anhydrase	0	0	0	1
Glutamate receptor ionotropic, NMDA 2A	0	4	0	5
Glutamate receptor ionotropic, NMDA 2B	0	4	0	5
Glutamate receptor ionotropic, NMDA 2C	0	4	0	6
Large neutral amino acids transporter small subunit 1	0	1	0	1
Glutaminyl-peptide cyclotransferase	0	1	0	1
Carbonic anhydrase	0	0	0	1
Carbonic anhydrase-like protein, putative	0	0	0	1
Carbonic anhydrase	0	0	0	1
Carbonic anhydrase	0	0	0	1
Glutamate receptor ionotropic, NMDA 2D	0	4	0	5
Carbonic anhydrase	0	0	0	1
Carbonic anhydrase 13	0	0	0	1
Glutamate receptor ionotropic, NMDA 3B	0	4	0	5
Carbonic anhydrase 4	0	0	0	1
Glutamate receptor ionotropic, NMDA 3A	0	4	0	5
Uracil nucleotide/cysteinyl leukotriene receptor	0	1	0	1
nonstructural protein 1	5	0	0	5
transcriptional regulator ERG isoform 3	3	0	0	3
Acid-sensing ion channel 3	0	1	0	1
Albumin	0	1	0	2
Albumin	0	0	3	3
Cholinesterase	0	3	0	3
Polyunsaturated fatty acid 5-lipoxygenase	0	2	0	5
UDP-glucuronosyltransferase 2B7	0	0	0	1
Prostaglandin G/H synthase 1	0	1	0	1
Caspase-1	0	3	0	3
Prostaglandin G/H synthase 2	0	2	0	4
UDP-glucuronosyltransferase 1A3	0	0	0	2
Aldo-keto reductase family 1 member C3	0	2	0	2
Caspase-3	0	3	0	3
Caspase-4	0	3	0	3
Caspase-5	0	3	0	3
Caspase-9	0	3	0	3
Fatty-acid amide hydrolase 1	0	4	0	4
Prostaglandin G/H synthase 2	0	1	0	1
Prostaglandin G/H synthase 1	0	2	0	4
Dehydrogenase/reductase SDR family member 9	0	1	0	1
Chain A, PROTEIN (PROTEASE)	0	1	0	1
Chain B, PROTEIN (PROTEASE)	0	1	0	1
Chain A, PROTEIN (PROTEASE)	0	1	0	1
Chain B, PROTEIN (PROTEASE)	0	1	0	1
Chain A, HIV-1 PROTEASE	0	1	0	1
Chain B, HIV-1 PROTEASE	0	1	0	1
Chain A, HIV-II PROTEASE	0	1	0	1
Chain B, HIV-II PROTEASE	0	1	0	1
Chain A, POL polyprotein	0	0	1	1
Chain B, POL polyprotein	0	0	1	1
Chain A, POL polyprotein	0	0	1	1
Chain B, POL polyprotein	0	0	1	1
Chain A, POL polyprotein	0	0	1	1
Chain B, POL polyprotein	0	0	1	1
Chain A, POL polyprotein	0	0	1	1
Chain B, POL polyprotein	0	0	1	1
Chain A, protease RETROPEPSIN	0	1	0	1
Chain B, protease RETROPEPSIN	0	1	0	1
Chain A, protease RETROPEPSIN	0	1	0	1
Chain B, protease RETROPEPSIN	0	1	0	1
Chain A, protease RETROPEPSIN	0	1	0	1
Chain B, protease RETROPEPSIN	0	1	0	1
Chain A, POL polyprotein	0	1	0	1
Chain B, POL polyprotein	0	1	0	1
Chain A, POL polyprotein	0	1	0	1
Chain B, POL polyprotein	0	1	0	1
Chain A, HIV-1 protease	0	1	0	1
Chain B, HIV-1 protease	0	1	0	1
Chain A, Pol polyprotein	0	1	0	1
Chain B, Pol polyprotein	0	1	0	1
Chain A, Pol polyprotein	0	1	0	1
Chain B, Pol polyprotein	0	1	0	1
Chain A, Pol polyprotein	0	1	0	1
Chain B, Pol polyprotein	0	1	0	1
Chain A, Pol polyprotein	0	1	0	1
Chain B, Pol polyprotein	0	1	0	1
Chain A, Hiv-1 Protease	0	1	0	1
Chain B, Hiv-1 Protease	0	1	0	1
Chain A, Hiv-1 Protease	0	1	0	1
Chain B, Hiv-1 Protease	0	1	0	1
Chain A, Hiv-1 Protease	0	1	0	1
Chain B, Hiv-1 Protease	0	1	0	1
Gag-Pol polyprotein	0	2	0	2
Gag-Pol polyprotein	0	2	0	2
Gag-Pol polyprotein	0	1	0	1
Gag polyprotein	0	1	0	1
Gag-Pol polyprotein	0	1	0	1
Gag-Pol polyprotein	0	3	0	3
Substance-K receptor	0	2	0	2
Gag-Pol polyprotein	0	1	0	1
Thromboxane-A synthase	0	0	0	1
Genome polyprotein	0	1	0	1
Protease	0	5	1	8
Protease	0	2	1	3
Protease	0	1	0	1
Glutamate receptor ionotropic, NMDA 2D	0	2	0	2
Acetylcholinesterase	0	3	0	3
Glutamate receptor ionotropic, NMDA 3B	0	2	0	2
Rap guanine nucleotide exchange factor 3	4	0	0	4
Sodium channel protein type 4 subunit alpha	0	2	0	2
Cholinesterase	0	2	0	2
Glutamate receptor ionotropic, NMDA 1	0	4	0	4
Glutamate receptor ionotropic, NMDA 2A	0	4	0	4
Glutamate receptor ionotropic, NMDA 2B	0	4	0	4
Glutamate receptor ionotropic, NMDA 2C	0	2	0	2
Glutamate receptor ionotropic, NMDA 3A	0	2	0	2
Cell division control protein 42 homolog	0	1	0	1
Ras-related C3 botulinum toxin substrate 1	0	1	0	1
Serine/threonine-protein kinase PAK 1	0	1	0	1
Hsf1 protein	0	0	1	1
Voltage-dependent L-type calcium channel subunit alpha-1F	0	4	0	4
Voltage-dependent L-type calcium channel subunit alpha-1D	0	4	0	4
Capsid protein	0	1	1	2
Voltage-dependent L-type calcium channel subunit alpha-1S	0	4	0	4
CAAX prenyl protease 2 isoform 2	0	0	0	1
streptokinase A precursor	0	0	2	2
Tubulin beta-4A chain	0	1	0	1
Tubulin beta chain	0	1	0	1
Tubulin alpha-3C chain	0	1	0	1
Tubulin alpha-1B chain	0	1	0	1
Tubulin alpha-4A chain	0	1	0	1
Tubulin beta-4B chain	0	1	0	1
DNA gyrase subunit A	0	2	0	3
DNA primase	0	1	0	1
Tubulin beta-3 chain	0	1	0	1
Tubulin beta-2A chain	0	1	0	1
Tubulin beta-8 chain	0	1	0	1
Tubulin alpha-3E chain	0	1	0	1
Tubulin alpha-1A chain	0	1	0	1
Tubulin alpha-1C chain	0	1	0	1
Tubulin beta-6 chain	0	1	0	1
Tubulin beta-2B chain	0	1	0	1
Tubulin beta-1 chain	0	1	0	1
Sodium channel protein type 1 subunit alpha	0	1	0	1
Sodium channel protein type 2 subunit alpha	0	1	0	1
Sodium channel protein type 3 subunit alpha	0	1	0	1
Potassium voltage-gated channel subfamily A member 5	0	1	0	1
Sodium channel protein type 9 subunit alpha	0	3	0	3
Potassium voltage-gated channel subfamily D member 2	0	1	0	1
Potassium channel subfamily K member 18	0	1	0	1
Sodium channel protein type 3 subunit alpha	0	2	0	2
Translocator protein	0	1	0	1
caspase 7, apoptosis-related cysteine protease	3	0	0	3
caspase-3	3	0	0	3
Caspase-7	2	0	0	2
caspase-3	2	0	0	2
Large neutral amino acids transporter small subunit 1	0	1	0	1
Liver carboxylesterase 1	0	0	0	1
Sodium-dependent dopamine transporter	0	3	0	3
Kappa-type opioid receptor	0	4	1	8
Macrophage migration inhibitory factor	0	2	0	2
Chain B, DIHYDROFOLATE REDUCTASE	0	0	1	1
Chain B, DIHYDROFOLATE REDUCTASE	0	0	1	1
Chain B, DIHYDROFOLATE REDUCTASE	0	0	1	1
Thymidylate synthase	0	2	0	2
Thymidylate synthase	0	2	0	2
nuclear receptor coactivator 1 isoform 1 [Homo sapiens]	0	1	0	1
transactivating tegument protein VP16 [Human herpesvirus 1]	0	1	0	1
nuclear receptor coactivator 3 isoform a	0	1	0	1
Toll-like receptor 4	0	1	0	1
Fatty-acid amide hydrolase 1	0	1	0	1
ATP-binding cassette sub-family C member 3	0	1	0	2
Dihydrofolate reductase	0	3	0	4
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	3	0	4
Thymidylate synthase	0	3	0	3
Tyrosine-protein kinase ABL1	0	0	1	1
Thymidylate synthase	0	4	0	4
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Thymidylate synthase	0	3	0	3
High mobility group protein B1	0	0	1	1
Dihydrofolate reductase	0	1	0	1
Thymidylate synthase	0	1	0	1
Dihydrofolate reductase	0	3	2	5
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Folate receptor beta	0	2	0	2
Cytochrome P450 11B1, mitochondrial	0	1	0	1
Folate receptor alpha	0	2	0	2
Dihydrofolate reductase	0	3	0	3
Histidine decarboxylase	0	1	2	3
Trifunctional purine biosynthetic protein adenosine-3	0	3	0	3
Bifunctional purine biosynthesis protein ATIC	0	4	0	4
Reduced folate transporter	0	3	0	3
Folylpolyglutamate synthase, mitochondrial	0	1	0	3
Solute carrier organic anion transporter family member 1A3	0	0	0	1
Dihydrofolate reductase	0	1	0	1
Pteridine reductase 1	0	1	0	1
Folylpolyglutamate synthase, mitochondrial	0	1	0	3
Bifunctional dihydrofolate reductase-thymidylate synthase	0	2	0	2
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Canalicular multispecific organic anion transporter 1	0	1	0	2
Trifunctional purine biosynthetic protein adenosine-3	0	2	0	2
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	1	0	1
ATP-binding cassette sub-family C member 11	0	0	0	1
Proton-coupled folate transporter	0	3	0	4
Multidrug resistance associated protein	0	1	0	2
Chain E, Fibrin beta chain	0	1	0	1
T cell receptor, partial	1	0	0	1
luteinizing hormone receptor	1	0	0	1
integrase, partial	0	1	0	1
lens epithelium-derived growth factor p75	0	1	0	1
Caspase 6, apoptosis-related cysteine peptidase	0	0	0	1
TSHR protein	1	0	0	1
Apoptotic peptidase activating factor 1	0	1	0	1
isocitrate dehydrogenase 1, partial	1	0	0	1
luciferase	1	0	0	1
serine-protein kinase ATM isoform a	1	0	0	1
neutrophil cytosol factor 1	0	1	0	1
caspase-9 isoform alpha precursor	0	1	0	1
histone deacetylase 9 isoform 3	2	0	0	2
caspase-3 isoform a preproprotein	0	1	0	1
protein AF-9 isoform a	0	0	0	1
Vpr	2	0	0	2
replicative DNA helicase	0	0	0	1
recombinase A	0	0	1	1
DNA repair protein RAD52 homolog isoform a	0	0	0	1
Glutathione reductase	0	1	0	1
Glutathione reductase, mitochondrial	0	1	0	2
Glycoprotein hormones alpha chain	1	0	0	1
Dihydrolipoyl dehydrogenase, mitochondrial	0	1	0	2
Cruzipain	0	1	0	1
Thioredoxin reductase 1, cytoplasmic	0	1	0	2
Dihydrolipoyl dehydrogenase	0	1	0	2
phosphoglycerate kinase	1	0	0	1
Androgen receptor	0	3	0	3
Nuclear receptor subfamily 1 group I member 2	0	0	1	1
Opioid receptor, delta 1b	0	1	0	1
Opioid receptor homologue	0	1	0	1
Acyl-CoA desaturase 1	0	1	0	1
Translocator protein	0	0	1	1
Proteinase-activated receptor 1	0	1	1	2
Nociceptin receptor	0	1	0	1
Mu-type opioid receptor	0	1	0	1
Beta-2 adrenergic receptor	0	2	0	2
Mas-related G-protein coupled receptor member X2	0	0	1	1
Mu-type opioid receptor	0	1	0	1
Adenosine receptor A1	0	1	0	1
UDP-glucuronosyltransferase 1A8	0	0	0	2
Hormone-sensitive lipase	0	1	0	1
Aldo-keto reductase family 1 member C4	0	1	0	1
Aldo-keto reductase family 1 member C2	0	1	0	1
Aldo-keto reductase family 1 member C1	0	1	0	1
Polyphenol oxidase 2	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-4	2	0	0	2
Cholesteryl ester transfer protein	0	1	0	1
Neuronal acetylcholine receptor subunit beta-2	2	0	0	2
D-amino-acid oxidase	0	1	0	1
Hydroxycarboxylic acid receptor 3	0	0	1	1
Nicotinamidase	0	1	0	1
Hydroxycarboxylic acid receptor 2	0	0	1	1
Hydroxycarboxylic acid receptor 2	0	2	1	3
D-aspartate oxidase	0	1	0	1
Hydroxycarboxylic acid receptor 2	0	1	1	2
Chain A, NAD-dependent deacetylase	0	1	0	1
Poly [ADP-ribose] polymerase 2	0	1	0	1
NAD-dependent histone deacetylase SIR2	0	1	0	1
Coagulation factor VII	0	1	0	1
Poly [ADP-ribose] polymerase 1	0	1	0	1
Tissue factor	0	1	0	1
Cytochrome P450 3A5	0	1	0	1
NAD-dependent protein deacetylase HST2	0	1	0	1
Protein mono-ADP-ribosyltransferase PARP15	0	1	0	1
NAD(+) hydrolase SARM1	0	1	0	1
NAD-dependent protein deacetylase sirtuin-2	0	1	0	1
NAD-dependent protein deacetylase sirtuin-6	0	1	0	1
NAD-dependent protein deacetylase sirtuin-1	0	1	0	1
NAD-dependent protein deacetylase sirtuin-3, mitochondrial	0	1	0	1
NAD-dependent protein deacylase sirtuin-5, mitochondrial	0	1	0	1
NAD-dependent protein deacetylase	0	1	0	1
STE24	0	0	0	1
CAAX prenyl protease	0	0	0	1
Trypsin	0	0	0	1
DNA gyrase subunit A	0	1	0	2
DNA gyrase subunit B	0	1	0	2
DNA gyrase subunit B	0	1	0	2
Platelet glycoprotein VI	0	0	1	1
Solute carrier family 22 member 8	0	1	0	1
Beta-lactamase OXA-7	0	0	0	1
Solute carrier family 15 member 2	0	1	0	1
Class D beta-lactamase	0	0	0	1
Solute carrier family 15 member 2	0	1	0	1
MecA	0	1	0	1
Cytochrome P450 2C19	0	5	0	5
5-hydroxytryptamine receptor 2B	0	10	0	10
Sodium-dependent dopamine transporter	0	4	1	5
MBT domain-containing protein 1	0	1	0	1
Lethal(3)malignant brain tumor-like protein 4	0	1	0	1
Lethal(3)malignant brain tumor-like protein 3	0	1	0	1
Lethal(3)malignant brain tumor-like protein 1	0	1	0	1
Chain A, Thymidylate Synthase	0	1	0	1
Chain A, Thymidylate Synthase	0	1	0	1
Chain A, Thymidylate Synthase	0	1	0	1
tyrosine-protein kinase Yes	1	0	0	1
Serine hydroxymethyltransferase, cytosolic	0	1	1	2
Thymidylate synthase	0	1	0	1
Sigma intracellular receptor 2	0	1	0	1
Sigma intracellular receptor 2	0	2	0	2
Chain A, Immunoglobulin	0	0	1	1
Chain B, Immunoglobulin	0	0	1	1
Cytochrome P450 2B6	0	4	0	4
Lysosomal Pro-X carboxypeptidase	0	1	0	1
Cholinesterase	0	1	0	1
Muscarinic acetylcholine receptor M5	0	0	1	2
Muscarinic acetylcholine receptor M3	0	0	1	2
Muscarinic acetylcholine receptor M2	0	0	1	2
Beta-2 adrenergic receptor	0	0	3	3
Beta-1 adrenergic receptor	0	0	2	2
Beta-3 adrenergic receptor	0	0	2	2
POU domain, class 2, transcription factor 1	0	0	0	1
Beta-1 adrenergic receptor	0	2	0	2
Alpha-1B adrenergic receptor	0	2	0	2
beta-2 adrenergic receptor	2	0	0	2
mu-type opioid receptor isoform MOR-1	0	0	1	1
5-hydroxytryptamine receptor 2A	0	0	1	1
interferon gamma precursor	0	0	0	1
Alpha-1A adrenergic receptor	0	1	1	2
Beta-casein	0	1	0	1
Interstitial collagenase	0	1	0	1
Matrix metalloproteinase-9	0	1	0	1
Alpha-2A adrenergic receptor	0	1	0	1
Alpha-mannosidase 2C1	0	0	1	1
Bromodomain-containing protein 2	0	2	0	2
5-hydroxytryptamine receptor 1B	0	1	0	1
3-oxo-5-alpha-steroid 4-dehydrogenase 2	0	2	0	2
Type-1 angiotensin II receptor	0	1	0	1
D(1A) dopamine receptor	2	0	0	2
Nuclear receptor subfamily 3 group C member 3	0	6	0	6
luciferase	0	0	0	1
Estrogen receptor	0	2	0	2
Progesterone receptor	0	2	0	3
Glucocorticoid receptor	0	1	1	2
Glucocorticoid receptor	0	0	1	1
Mineralocorticoid receptor	0	2	1	3
Androgen receptor	0	2	0	2
Glutamine synthetase	0	0	1	1
Histamine H1 receptor	0	1	1	2
Nociceptin receptor	0	0	1	1
Estrogen receptor beta	0	2	0	2
Solute carrier family 22 member 1	0	1	0	1
Sterol O-acyltransferase 1	0	1	0	1
Solute carrier family 22 member 2	0	1	0	1
Acetylcholinesterase	0	1	0	1
Sterol O-acyltransferase 1	0	1	0	1
Solute carrier family 22 member 4	0	1	0	1
DNA (cytosine-5)-methyltransferase 3-like	0	1	0	1
DNA (cytosine-5)-methyltransferase 3A	0	1	0	1
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)	2	0	0	2
heat shock protein HSP 90-alpha isoform 2	0	0	0	1
heat shock protein 90, putative	0	0	0	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Fatty-acid amide hydrolase 1	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-1	0	0	0	1
Gamma-aminobutyric acid receptor subunit beta-1	0	0	0	1
Gamma-aminobutyric acid receptor subunit alpha-2	0	0	0	1
Gamma-aminobutyric acid receptor subunit alpha-3	0	0	0	1
Gamma-aminobutyric acid receptor subunit alpha-1	0	1	1	2
Gamma-aminobutyric acid receptor subunit beta-1	0	0	1	1
Gamma-aminobutyric acid receptor subunit gamma-2	0	1	1	2
Gamma-aminobutyric acid receptor subunit alpha-4	0	0	0	1
Gamma-aminobutyric acid receptor subunit gamma-2	0	0	0	1
Sodium- and chloride-dependent GABA transporter 1	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-3	0	1	1	2
Gamma-aminobutyric acid receptor subunit alpha-5	0	0	1	1
Sodium- and chloride-dependent GABA transporter 2	0	1	0	1
Sodium- and chloride-dependent GABA transporter 3	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-3	0	0	1	1
Gamma-aminobutyric acid receptor subunit alpha-2	0	0	1	1
Gamma-aminobutyric acid receptor subunit beta-2	0	0	1	1
Sodium- and chloride-dependent betaine transporter	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-4	0	0	1	1
Gamma-aminobutyric acid receptor subunit alpha-6	0	0	1	1
Chain A, dATP pyrophosphohydrolase	0	1	0	1
Chain A, Adenylate cyclase type 5	0	1	0	1
Chain B, Adenylate cyclase type 2	0	1	0	1
Butyrophilin subfamily 3 member A1	0	0	1	1
4-hydroxy-3-methylbut-2-enyl diphosphate reductase	0	1	0	1
Farnesyl diphosphate synthase	0	1	0	1
H	0	1	0	1
Phosphotransferase	0	1	0	1
Farnesyl diphosphate synthase	0	1	0	1
D(1A) dopamine receptor	0	2	0	2
Histamine H2 receptor	0	2	0	2
5-hydroxytryptamine receptor 2A	0	6	0	6
5-hydroxytryptamine receptor 2C	0	1	0	1
5-hydroxytryptamine receptor 7	0	1	0	1
5-hydroxytryptamine receptor 2A	0	1	0	1
5-hydroxytryptamine receptor 6	0	1	0	1
3-hydroxy-3-methylglutaryl-coenzyme A reductase	0	1	0	1
D(2) dopamine receptor	0	1	0	1
5-hydroxytryptamine receptor 2B	0	1	0	1
Transporter	0	1	0	1
5-hydroxytryptamine receptor 1A	0	1	0	1
Transporter	0	2	0	2
Histamine H3 receptor	0	1	0	1
atrial natriuretic peptide receptor 2 precursor	1	0	0	1
Transcriptional activator protein LuxR	0	1	0	1
Melanocortin receptor 5	0	2	0	2
Envelope glycoprotein	0	0	1	1
exodeoxyribonuclease V subunit RecD	0	1	0	1
exodeoxyribonuclease V subunit RecB	0	1	0	1
exodeoxyribonuclease V subunit RecC	0	1	0	1
Thymidine kinase, cytosolic	0	1	0	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Acetylcholinesterase	0	1	0	1
Beta-adrenergic receptor kinase 1	0	0	1	1
Beta-2 adrenergic receptor	0	0	1	3
cGMP-gated cation channel alpha-1	0	0	1	1
Sodium channel protein type 7 subunit alpha	0	1	0	1
Sodium channel protein type 2 subunit alpha	0	1	0	1
Sodium channel protein type 8 subunit alpha	0	1	0	1
Cytochrome P450 2C8	0	1	0	1
Sterol 14-alpha-demethylase	0	0	1	1
14-alpha sterol demethylase	0	0	1	1
Cholesterol side-chain cleavage enzyme, mitochondrial	0	0	1	1
Lanosterol 14-alpha demethylase	0	0	1	1
Cytochrome P450 144	0	0	1	1
Steroid C26-monooxygenase	0	0	1	1
Steroid C26-monooxygenase	0	0	1	1
Sterol 14-alpha demethylase	0	0	1	1
14-alpha sterol demethylase	0	0	1	1
14-alpha sterol demethylase	0	0	1	1
Cholesterol 24-hydroxylase	0	2	1	3
Proprotein convertase subtilisin/kexin type 7	0	1	0	1
Vitamin K epoxide reductase complex subunit 1-like protein 1	0	1	0	1
Vitamin K epoxide reductase complex subunit 1	0	1	0	1
Vitamin K epoxide reductase complex subunit 1-like protein 1	0	1	0	1
Vitamin K epoxide reductase complex subunit 1	0	2	0	2
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

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Studies (347)

Protein Targets (1,091)

Rib Fractures

Synonyms(1)

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Studies (347)

Drugs Studied (194)

Protein Targets (1,091)