Apraxias

A group of cognitive disorders characterized by the inability to perform previously learned skills that cannot be attributed to deficits of motor or sensory function. The two major subtypes of this condition are ideomotor (see APRAXIA, IDEOMOTOR) and ideational apraxia, which refers to loss of the ability to mentally formulate the processes involved with performing an action. For example, dressing apraxia may result from an inability to mentally formulate the act of placing clothes on the body. Apraxias are generally associated with lesions of the dominant PARIETAL LOBE and supramarginal gyrus. (From Adams et al., Principles of Neurology, 6th ed, pp56-7)

Synonym
Apraxias

Timeframe	Studies, This Condition (%)	All Conditions %
pre-1990	71 (27.10)	23.3326
1990's	48 (18.32)	12.5806
2000's	65 (24.81)	18.1394
2010's	53 (20.23)	28.8240
2020's	25 (9.54)	9.53

Drug	Relationship Strength	Studies	Trials
ammonium hydroxide	low	2	0
carbon monoxide	low	6	0
carnitine	medium	1	1
choline	low	1	0
bupropion	low	1	0
phosphoglycolate	low	1	0
creatine	low	1	0
formaldehyde	low	1	0
dihydroxyphenylalanine	low	2	0
methanol	low	1	0
phosphoric acid	low	1	0
phthalic acid	low	1	0
thiamine	low	2	0
3,4-methylenedioxyamphetamine	low	1	0
amantadine	low	1	0
amitriptyline	low	1	0
amobarbital	low	1	0
carbamazepine	low	2	0
cetirizine	low	1	0
chlorambucil	low	1	0
deferoxamine	low	3	0
amphetamine	low	1	0
valproic acid	low	1	0
haloperidol	low	2	0
imipramine	low	2	0
iofetamine	low	2	0
iproniazid	low	1	0
ketoprofen	low	1	0
lamotrigine	low	1	0
meclofenoxate	low	1	0
methyl salicylate	low	1	0
methyl methanesulfonate	low	1	0
mirtazapine	low	1	0
apnea	low	3	0
nimodipine	low	1	0
oxidopamine	low	1	0
benoxinate	low	1	0
pantoprazole	low	1	0
phenobarbital	low	1	0
piracetam	low	1	0
pirenzepine	low	1	0
procaine	low	2	0
riluzole	low	1	0
sulpiride	low	1	0
temozolomide	low	1	0
trihexyphenidyl	low	2	0
mitomycin	low	3	0
prednisolone	low	2	0
thyroxine	low	1	0
penicillamine	low	1	0
prednisone	low	1	0
penicillin g	low	1	0
serine	medium	2	1
aspartic acid	low	1	0
lysine	low	2	0
physostigmine	low	1	0
apomorphine	low	1	0
galactose	medium	1	1
levodopa	low	9	0
adenosine monophosphate	low	4	0
leucine	low	1	0
valine	low	1	0
threonine	low	1	0
tryptophan	low	1	0
arginine	low	1	0
methanesulfonic acid	low	1	0
tromethamine	low	1	0
methylprednisolone	low	2	0
n-vinyl-2-pyrrolidinone	low	1	0
dibenzylamine	low	1	0
framycetin	low	1	0
thiazoles	low	6	0
paraoxon	low	1	0
galantamine	low	1	0
lithium carbonate	low	3	0
galactitol	medium	1	1
silver	low	1	0
technetium	low	1	0
xenon	low	1	0
camptothecin	low	1	0
trolamine salicylate	low	1	0
phenyl acetate	low	1	0
glutamic acid	low	1	0
adenosine diphosphate ribose	low	1	0
etoposide	low	1	0
fomesafen	low	12	0
aripiprazole	low	1	0
n-acetylaspartic acid	low	1	0
triazoles	low	1	0
fluorodeoxyglucose f18	medium	20	2
tetraconazole	low	1	0
homocysteine	low	1	0
droxidopa	medium	2	1
deoxyglucose	low	5	0
galactose-1-phosphate	medium	1	1
methotrexate	low	1	0
2-fluorodopa	low	1	0
dexketoprofen trometamol	low	1	0
inositol 3-phosphate	medium	10	1
metrizamide	low	1	0
tacrolimus	low	2	0
cocaine	low	1	0
eicosapentaenoic acid	low	1	0
tempo	low	1	0
2-(4'-(methylamino)phenyl)-6-hydroxybenzothiazole	low	6	0
lithium	low	3	0
coenzyme q10	low	2	0
tin	low	2	0
rubidium	low	1	0
aluminum	low	7	0
cysteine	low	2	0
2-carbomethoxy-8-(3-fluoropropyl)-3-(4-iodophenyl)tropane	medium	3	1
technetium tc 99m exametazime	low	4	0
scopolamine hydrobromide	low	1	0
mefloquine	low	2	0
jaw	low	6	0
ubiquinone	low	2	0
vitamin b 12	low	1	0
amyloid beta-peptides	low	1	0
acyclovir	low	1	0
guanosine monophosphate	low	1	0
folic acid	low	1	0
valacyclovir	low	1	0
olanzapine	low	1	0
valganciclovir	low	1	0
methylnitronitrosoguanidine	low	1	0
eye	low	4	0
ego	low	1	0
technetium tc 99m bicisate	low	2	0

Protein Targets (1,150)

Protein	Potency Measurements	Inhibition Measurements	Activation Measurements	Drugs
Amyloid-beta precursor protein	0	3	0	3
Sodium-dependent dopamine transporter	0	13	0	13
5-hydroxytryptamine receptor 2C	0	17	2	20
5-hydroxytryptamine receptor 2A	0	17	2	19
5-hydroxytryptamine receptor 1A	0	13	2	15
Sodium-dependent noradrenaline transporter	0	19	0	19
Sodium-dependent dopamine transporter	0	11	1	12
5-hydroxytryptamine receptor 1B	0	9	2	11
5-hydroxytryptamine receptor 1D	0	8	2	10
5-hydroxytryptamine receptor 1F	0	8	2	10
5-hydroxytryptamine receptor 2B	0	14	3	17
5-hydroxytryptamine receptor 6	0	4	2	6
Sodium-dependent serotonin transporter	0	19	1	20
Sodium-dependent serotonin transporter	0	8	1	10
5-hydroxytryptamine receptor 7	0	8	2	10
5-hydroxytryptamine receptor 5A	0	4	2	6
5-hydroxytryptamine receptor 5B	0	4	2	6
5-hydroxytryptamine receptor 3A	0	5	2	7
5-hydroxytryptamine receptor 4	0	4	2	6
5-hydroxytryptamine receptor 3B	0	5	2	7
Chain E, Purine nucleoside phosphorylase	0	1	0	1
Chain A, HADH2 protein	12	0	0	12
Chain B, HADH2 protein	12	0	0	12
Chain A, ATP-DEPENDENT DNA HELICASE Q1	4	0	0	4
Chain A, Ferritin light chain	8	0	0	8
Thymidine kinase	0	1	0	1
thioredoxin reductase	22	0	0	22
phosphopantetheinyl transferase	14	0	0	14
GLS protein	21	0	0	21
TDP1 protein	32	0	0	32
Smad3	1	0	0	1
thyroid stimulating hormone receptor	18	0	0	18
EWS/FLI fusion protein	18	0	0	18
arylsulfatase A	15	0	0	15
euchromatic histone-lysine N-methyltransferase 2	34	0	0	34
activating transcription factor 6	11	0	0	11
Histone H2A.x	9	0	0	9
Bloom syndrome protein isoform 1	17	0	0	17
hemoglobin subunit beta	2	0	0	2
atrial natriuretic peptide receptor 1 precursor	4	0	0	4
ubiquitin carboxyl-terminal hydrolase 2 isoform a	6	0	0	6
lamin isoform A-delta10	25	0	0	25
Solute carrier family 22 member 1	0	6	0	10
ATP-binding cassette sub-family C member 3	0	26	0	26
Multidrug resistance-associated protein 4	0	26	0	28
Solute carrier family 22 member 6	0	2	0	3
Bile salt export pump	0	9	0	9
Bile salt export pump	0	42	0	42
Purine nucleoside phosphorylase	0	2	0	2
Thymidine kinase, cytosolic	0	0	0	1
POU domain, class 2, transcription factor 2	0	0	0	1
Cytochrome P450 2C9	0	14	1	16
Cytochrome P450 2J2	0	10	0	11
Disintegrin and metalloproteinase domain-containing protein 17	5	0	0	5
Purine nucleoside phosphorylase	0	0	1	1
Solute carrier family 22 member 6	0	1	0	3
Thymidine kinase	0	1	0	1
Solute carrier family 22 member 8	0	2	0	5
Canalicular multispecific organic anion transporter 1	0	27	0	28
Thymidine kinase	0	1	0	1
Transient receptor potential cation channel subfamily M member 2	0	1	1	2
Chain A, Glycogen Phosphorylase B	0	0	1	1
Chain B, Glycogen Phosphorylase B	0	0	1	1
Chain A, ADP-dependent glucokinase	0	1	0	1
Chain A, Ribonuclease pancreatic	0	1	0	1
Chain A, Ribonuclease pancreatic	0	1	0	1
Chain A, phosphodiesterase-nucleotide pyrophosphatase	0	1	0	1
Chain A, GLYCOGEN PHOSPHORYLASE B	0	0	1	1
Chain B, GLYCOGEN PHOSPHORYLASE B	0	0	1	1
Chain A, GLYCOGEN PHOSPHORYLASE B	0	0	1	1
RAR-related orphan receptor gamma	27	0	0	27
AR protein	35	0	0	35
regulator of G-protein signaling 4	14	0	0	14
glucocorticoid receptor [Homo sapiens]	26	0	0	26
estrogen-related nuclear receptor alpha	34	0	0	34
v-jun sarcoma virus 17 oncogene homolog (avian)	15	0	0	15
2'-deoxynucleoside 5'-phosphate N-hydrolase 1	0	1	0	1
Mitogen-activated protein kinase kinase kinase 7	0	0	1	1
2'-deoxynucleoside 5'-phosphate N-hydrolase 1	0	1	0	1
5'-AMP-activated protein kinase subunit beta-2	0	0	1	1
Alcohol dehydrogenase E chain	0	1	0	1
Alcohol dehydrogenase S chain	0	1	0	1
L-lactate dehydrogenase A chain	0	1	1	2
Adenylate kinase isoenzyme 1	0	0	0	1
Fructose-1,6-bisphosphatase 1	0	1	0	1
Alkaline phosphatase, tissue-nonspecific isozyme	0	2	0	3
Fructose-1,6-bisphosphatase 1	0	1	0	1
2-dehydropantoate 2-reductase	0	2	1	3
Inosine-5'-monophosphate dehydrogenase	0	1	0	1
Proto-oncogene tyrosine-protein kinase Src	0	2	0	2
Amine oxidase [flavin-containing] B	0	2	0	2
5'-nucleotidase	0	0	0	1
Choline O-acetyltransferase	0	1	0	1
Adenylate kinase 2, mitochondrial	0	1	0	2
GTP:AMP phosphotransferase AK3, mitochondrial	0	0	0	1
Adenosine receptor A1	0	1	1	2
Adenylate kinase isoenzyme 1	0	1	0	2
P2Y purinoceptor 2	0	0	1	1
P2Y purinoceptor 1	0	0	1	1
P2Y purinoceptor 1	0	0	1	1
5'-AMP-activated protein kinase subunit gamma-1	0	0	2	2
5'-AMP-activated protein kinase catalytic subunit alpha-2	0	0	1	1
Adenylate kinase 2, mitochondrial	0	0	0	1
Glycine--tRNA ligase	0	1	0	1
5'-AMP-activated protein kinase catalytic subunit alpha-1	0	0	2	2
Adenosine deaminase-like protein	0	0	0	1
Protease	0	3	1	4
P2Y purinoceptor 11	0	0	1	1
Histamine H3 receptor	0	1	0	1
5'-AMP-activated protein kinase subunit gamma-3	0	0	1	1
5'-AMP-activated protein kinase subunit gamma-2	0	0	1	1
5'-AMP-activated protein kinase subunit beta-1	0	0	2	2
ATP-dependent phosphofructokinase	25	0	0	25
acetylcholinesterase	10	0	0	10
NFKB1 protein, partial	8	0	0	8
GLI family zinc finger 3	24	0	0	24
signal transducer and activator of transcription 6, interleukin-4 induced	1	0	0	1
estrogen nuclear receptor alpha	42	0	0	42
putative alpha-glucosidase	2	0	0	2
thyroid hormone receptor beta isoform 2	28	0	0	28
heat shock protein beta-1	5	0	0	5
peripheral myelin protein 22	16	0	0	16
histone acetyltransferase KAT2A isoform 1	16	0	0	16
Solute carrier family 22 member 2	0	4	0	6
Glutamate receptor ionotropic, NMDA 2D	0	2	0	2
Glutamate receptor ionotropic, NMDA 3B	0	2	0	2
Matrix protein 2	0	1	1	2
Matrix protein 2	0	1	2	3
Glutamate receptor ionotropic, NMDA 1	0	7	1	11
Spike glycoprotein	17	0	0	17
Glutamate receptor ionotropic, NMDA 2A	0	7	1	11
Glutamate receptor ionotropic, NMDA 2B	0	7	1	11
Glutamate receptor ionotropic, NMDA 2C	0	7	1	11
Glutamate receptor ionotropic, NMDA 1	0	2	0	2
Glutamate receptor ionotropic, NMDA 2A	0	2	0	2
Glutamate receptor ionotropic, NMDA 2B	0	2	0	2
Glutamate receptor ionotropic, NMDA 2C	0	2	0	2
Glutamate receptor ionotropic, NMDA 2D	0	7	1	11
Solute carrier family 22 member 1	0	4	0	5
Glutamate receptor ionotropic, NMDA 3A	0	2	0	2
Glutamate receptor ionotropic, NMDA 3B	0	7	1	11
Multidrug and toxin extrusion protein 1	0	6	0	6
Solute carrier family 22 member 2	0	4	0	5
Glutamate receptor ionotropic, NMDA 3A	0	7	1	11
USP1 protein, partial	14	0	0	14
cytochrome P450 family 3 subfamily A polypeptide 4	15	0	0	15
cytochrome P450 2D6	13	0	0	13
cytochrome P450 2D6 isoform 1	10	0	0	10
D(1A) dopamine receptor	10	0	0	10
chromobox protein homolog 1	15	0	0	15
atrial natriuretic peptide receptor 2 precursor	5	0	0	5
serine/threonine-protein kinase mTOR isoform 1	4	0	0	4
nuclear factor erythroid 2-related factor 2 isoform 1	22	0	0	22
muscarinic acetylcholine receptor M1	13	0	0	13
Polyunsaturated fatty acid lipoxygenase ALOX15B	6	0	0	6
Voltage-dependent L-type calcium channel subunit alpha-1F	0	5	0	5
5-hydroxytryptamine receptor 4	0	8	0	8
Albumin	0	0	4	4
High affinity nerve growth factor receptor	0	1	2	3
Aldo-keto reductase family 1 member B1	0	9	0	9
Muscarinic acetylcholine receptor M2	0	11	1	12
Muscarinic acetylcholine receptor M4	0	13	1	14
Muscarinic acetylcholine receptor M1	0	11	0	11
Muscarinic acetylcholine receptor M3	0	9	0	9
Muscarinic acetylcholine receptor M4	0	9	0	9
Muscarinic acetylcholine receptor M5	0	10	0	10
Muscarinic acetylcholine receptor M5	0	13	0	13
Alpha-2A adrenergic receptor	0	12	0	12
Muscarinic acetylcholine receptor M2	0	11	1	12
Muscarinic acetylcholine receptor M1	0	13	3	17
Angiotensin-converting enzyme	0	6	0	6
D(2) dopamine receptor	0	17	5	30
Alpha-2B adrenergic receptor	0	9	0	9
Alpha-2C adrenergic receptor	0	11	0	11
Muscarinic acetylcholine receptor M3	0	13	1	14
D(1A) dopamine receptor	0	11	2	17
D(1B) dopamine receptor	0	7	0	10
UDP-glucuronosyltransferase 1A4	0	1	0	7
Histamine H2 receptor	0	6	0	6
Alpha-1D adrenergic receptor	0	9	0	9
5-hydroxytryptamine receptor 2A	0	14	0	16
5-hydroxytryptamine receptor 2C	0	12	1	13
Histamine H1 receptor	0	6	0	6
Histamine H1 receptor	0	14	3	19
D(3) dopamine receptor	0	14	4	25
Sodium channel protein type 1 subunit alpha	0	4	0	4
Sodium channel protein type 4 subunit alpha	0	5	0	7
UDP-glucuronosyltransferase 1A3	0	0	0	3
5-hydroxytryptamine receptor 2B	0	11	1	12
Alpha-1A adrenergic receptor	0	13	1	14
Histamine H2 receptor	8	2	0	12
D(1A) dopamine receptor	4	1	0	5
5-hydroxytryptamine receptor 6	0	9	0	10
5-hydroxytryptamine receptor 7	0	4	0	4
Voltage-dependent N-type calcium channel subunit alpha-1B	0	3	0	3
Sodium channel protein type 7 subunit alpha	0	3	0	3
Voltage-dependent L-type calcium channel subunit alpha-1D	0	5	0	5
Potassium voltage-gated channel subfamily H member 2	0	17	0	17
Voltage-dependent L-type calcium channel subunit alpha-1S	0	5	0	5
Voltage-dependent L-type calcium channel subunit alpha-1C	0	6	0	6
Sodium channel protein type 5 subunit alpha	0	4	0	4
Sodium channel protein type 9 subunit alpha	0	6	0	6
Sigma non-opioid intracellular receptor 1	0	5	1	6
Nuclear receptor subfamily 3 group C member 3	0	5	0	5
Sodium channel protein type 2 subunit alpha	0	5	0	5
Ataxin-2	17	0	0	17
Sigma non-opioid intracellular receptor 1	0	11	1	12
Sodium channel protein type 3 subunit alpha	0	5	0	5
Sodium channel protein type 11 subunit alpha	0	3	0	3
Sodium channel protein type 8 subunit alpha	0	3	0	3
Histamine H3 receptor	0	3	0	3
Sodium channel protein type 10 subunit alpha	0	4	0	4
farnesoid X nuclear receptor	14	0	0	14
Solute carrier family 22 member 3	0	1	0	1
Phenylethanolamine N-methyltransferase	0	2	0	2
Cytochrome P450 2A6	0	2	0	2
Substance-P receptor	0	1	0	1
Cytochrome P450 2A5	0	1	0	1
Beta-2 adrenergic receptor	0	2	0	2
Sigma non-opioid intracellular receptor 1	0	7	1	8
ATAD5 protein, partial	13	0	0	13
Microtubule-associated protein tau	14	0	0	14
neuropeptide S receptor isoform A	3	0	0	3
Chain A, TYROSYL-DNA PHOSPHODIESTERASE	11	0	0	11
Chain A, Putative fructose-1,6-bisphosphate aldolase	6	0	0	6
Chain A, 2-oxoglutarate Oxygenase	11	0	0	11
Luciferase	10	0	0	10
hypoxia-inducible factor 1 alpha subunit	10	0	0	10
aldehyde dehydrogenase 1 family, member A1	19	0	0	19
estrogen receptor 2 (ER beta)	11	0	0	11
nuclear receptor subfamily 1, group I, member 3	22	0	0	22
progesterone receptor	17	0	0	17
retinoic acid nuclear receptor alpha variant 1	27	0	0	27
peroxisome proliferator-activated receptor delta	14	0	0	14
peroxisome proliferator activated receptor gamma	19	0	0	19
aryl hydrocarbon receptor	15	0	0	15
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a	18	0	0	18
thyroid stimulating hormone receptor	7	0	0	7
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a	9	0	0	9
cellular tumor antigen p53 isoform a	5	0	0	5
cytochrome P450 2C19 precursor	7	0	0	7
cytochrome P450 2C9 precursor	5	0	0	5
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1	7	0	0	7
vitamin D3 receptor isoform VDRA	12	0	0	12
potassium voltage-gated channel subfamily H member 2 isoform d	15	0	0	15
mitogen-activated protein kinase 1	7	0	0	7
nuclear receptor ROR-gamma isoform 1	10	0	0	10
geminin	24	0	0	24
cytochrome P450 3A4 isoform 1	9	0	0	9
lethal factor (plasmid)	9	0	0	9
Gamma-aminobutyric acid receptor subunit pi	9	1	0	10
Voltage-dependent calcium channel gamma-2 subunit	11	0	0	11
Cellular tumor antigen p53	25	0	0	25
Integrin beta-3	4	0	1	5
Integrin alpha-IIb	4	0	1	5
5-hydroxytryptamine receptor 1A	0	9	3	12
Tryptophan 5-hydroxylase 1	0	2	0	2
Gamma-aminobutyric acid receptor subunit beta-1	9	1	0	10
Alpha-1B adrenergic receptor	0	12	1	13
Gamma-aminobutyric acid receptor subunit delta	9	1	0	10
Gamma-aminobutyric acid receptor subunit gamma-2	9	1	0	10
D	0	12	0	12
D(3) dopamine receptor	0	9	0	9
Alpha-2B adrenergic receptor	0	8	1	9
Glutamate receptor 2	13	2	1	16
Gamma-aminobutyric acid receptor subunit alpha-5	9	1	0	10
Gamma-aminobutyric acid receptor subunit alpha-3	9	1	0	10
D(2) dopamine receptor	0	6	0	6
D(4) dopamine receptor	0	11	2	18
Alpha-2C adrenergic receptor	0	8	1	9
Alpha-2A adrenergic receptor	0	8	1	9
Gamma-aminobutyric acid receptor subunit gamma-1	9	1	0	10
Gamma-aminobutyric acid receptor subunit alpha-2	9	1	0	10
Alpha-1D adrenergic receptor	0	12	1	13
D(1B) dopamine receptor	0	7	0	7
Gamma-aminobutyric acid receptor subunit alpha-4	9	1	0	10
Gamma-aminobutyric acid receptor subunit gamma-3	9	1	0	10
Gamma-aminobutyric acid receptor subunit alpha-6	9	1	0	10
D(4) dopamine receptor	0	9	1	10
D(2) dopamine receptor	0	14	2	16
Gamma-aminobutyric acid receptor subunit alpha-1	9	1	0	10
Gamma-aminobutyric acid receptor subunit beta-3	9	1	0	10
Gamma-aminobutyric acid receptor subunit beta-2	9	1	0	10
E3 ubiquitin-protein ligase Mdm2	0	1	0	1
D	0	1	0	1
GABA theta subunit	9	1	0	10
D	0	5	0	5
ATPase family AAA domain-containing protein 5	13	0	0	13
Gamma-aminobutyric acid receptor subunit epsilon	9	1	0	10
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE	18	0	0	18
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	1	1
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	1	1
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	1	1
alpha-galactosidase	4	0	0	4
flap endonuclease 1	8	0	0	8
DNA polymerase iota isoform a (long)	11	0	0	11
Cytochrome P450 3A4	0	11	0	15
Nitric oxide synthase, endothelial	0	0	0	2
Nitric oxide synthase, brain	0	0	0	1
Nitric oxide synthase, brain	0	0	0	1
Nitric oxide synthase, inducible	0	0	0	1
Nitric oxide synthase, inducible	0	0	1	3
Cationic amino acid transporter 3	0	2	0	2
Chain A, JmjC domain-containing histone demethylation protein 3A	4	0	0	4
5-hydroxytryptamine receptor 3E	0	3	0	3
SMAD family member 2	7	0	0	7
Fumarate hydratase	5	0	0	5
PPM1D protein	3	0	0	3
SMAD family member 3	7	0	0	7
retinoid X nuclear receptor alpha	14	0	0	14
pregnane X nuclear receptor	24	0	0	24
G	8	0	0	8
polyprotein	5	0	0	5
67.9K protein	7	0	0	7
vitamin D (1,25- dihydroxyvitamin D3) receptor	17	0	0	17
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)	2	0	0	2
lysosomal alpha-glucosidase preproprotein	6	0	0	6
mu-type opioid receptor isoform MOR-1	0	0	2	2
nuclear factor erythroid 2-related factor 2 isoform 2	13	0	0	13
transcriptional regulator ERG isoform 3	3	0	0	3
5-hydroxytryptamine receptor 2A	0	0	2	2
5-hydroxytryptamine receptor 3A	0	2	0	2
5-hydroxytryptamine receptor 3B	0	3	0	3
Interferon beta	11	0	0	11
HLA class I histocompatibility antigen, B alpha chain	8	0	0	8
ATP-dependent translocase ABCB1	0	6	0	10
Neuronal acetylcholine receptor subunit alpha-4	3	1	0	4
Neuronal acetylcholine receptor subunit beta-2	3	1	0	4
Histamine H1 receptor	0	3	1	4
5-hydroxytryptamine receptor 7	0	7	0	7
Alpha-1A adrenergic receptor	0	6	0	6
Alpha-1B adrenergic receptor	0	4	0	4
5-hydroxytryptamine receptor 3A	0	4	0	4
3-hydroxy-3-methylglutaryl-coenzyme A reductase	0	3	0	3
Inositol monophosphatase 1	5	0	0	5
5-hydroxytryptamine receptor 3D	0	3	0	3
Multidrug and toxin extrusion protein 2	0	3	0	3
5-hydroxytryptamine receptor 3C	0	3	0	3
Inositol hexakisphosphate kinase 1	8	0	0	8
cytochrome P450 2C9, partial	8	0	0	8
Metabotropic glutamate receptor 6	0	1	2	4
Excitatory amino acid transporter 4	0	2	0	2
Glutamate transporter homolog	0	0	1	1
Carbonic anhydrase 1	0	7	0	13
Carbonic anhydrase 2	0	7	1	14
N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase	0	1	0	1
5-hydroxytryptamine receptor 1D	0	0	0	1
Excitatory amino acid transporter 1	0	3	0	4
Excitatory amino acid transporter 2	0	3	0	4
Excitatory amino acid transporter 3	0	3	0	4
Metabotropic glutamate receptor 1	0	1	2	4
Metabotropic glutamate receptor 2	0	1	2	4
Carbonic anhydrase-like protein, putative	0	0	0	4
Carbonic anhydrase 4	0	1	0	2
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	7	0	0	7
IDH1	10	0	0	10
Acetylcholine receptor subunit alpha	0	1	0	1
Acetylcholine receptor subunit gamma	0	1	0	1
Integrin alpha-5	0	1	0	1
Acetylcholine receptor subunit beta	0	1	0	1
UDP-glucuronosyltransferase 2B7	0	3	0	8
Neuronal acetylcholine receptor subunit beta-2	0	1	0	2
UDP-glucuronosyltransferase 1-6	0	1	0	2
Cytochrome P450 2B6	0	0	1	3
UDP-glucuronosyltransferase 1A1	0	3	0	4
Neuronal acetylcholine receptor subunit beta-4	0	1	0	2
Neuronal acetylcholine receptor subunit alpha-3	0	1	0	1
Cytochrome P450 2C19	0	3	0	5
UDP-glucuronosyltransferase 2B10	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-7	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-4	0	1	0	2
Acetylcholine receptor subunit delta	0	1	0	1
Mu-type opioid receptor	0	6	2	9
Delta-type opioid receptor	0	3	1	5
Kappa-type opioid receptor	0	3	3	7
Chain A, Cruzipain	3	0	0	3
DNA topoisomerase	0	1	0	1
15-lipoxygenase, partial	8	0	0	8
Thrombopoietin	3	0	0	3
glucocerebrosidase	4	0	0	4
peripheral myelin protein 22 isoform 1	9	0	0	9
huntingtin isoform 2	1	0	0	1
ras-related protein Rab-9A	2	0	0	2
eukaryotic translation initiation factor 2-alpha kinase 3 isoform 1 precursor	0	0	1	1
survival motor neuron protein isoform d	7	0	0	7
M-phase phosphoprotein 8	8	0	0	8
muscleblind-like protein 1 isoform 1	5	0	0	5
relaxin receptor 1 isoform 1	1	0	0	1
Telomerase reverse transcriptase	0	1	0	1
Serine/threonine-protein kinase Chk1	0	0	1	1
Histone deacetylase 3	0	3	0	3
Type-2 restriction enzyme ScaI	0	1	0	1
Deoxyribonuclease-2-alpha	0	1	0	1
Tyrosyl-DNA phosphodiesterase 2	0	1	0	1
Deoxyribonuclease-1	0	1	0	1
Type-2 restriction enzyme PstI	0	1	0	1
Type-2 restriction enzyme EcoRI	0	1	0	1
Prothrombin	0	0	1	3
DNA ligase	0	1	0	1
Heterogeneous nuclear ribonucleoprotein A1	0	0	1	1
DNA topoisomerase 1	0	2	1	8
DNA topoisomerase 2-alpha	0	2	1	8
Type-2 restriction enzyme BamHI	0	1	0	1
Somatostatin receptor type 1	0	1	0	1
Somatostatin receptor type 2	0	1	0	1
Somatostatin receptor type 4	0	1	0	1
Somatostatin receptor type 3	0	1	0	1
Somatostatin receptor type 5	0	1	0	1
Type-2 restriction enzyme HindIII	0	1	0	1
Histone deacetylase 4	0	3	0	3
Ribonuclease pancreatic	0	1	0	1
DNA topoisomerase 2-beta	0	1	1	9
DNA topoisomerase 1	0	1	0	2
Histone deacetylase 1	0	3	0	3
DNA topoisomerase 1	0	1	0	1
Integrase	0	2	0	2
Histone deacetylase 7	0	3	0	3
Histone deacetylase 2	0	3	0	3
DNA topoisomerase type IB small subunit	0	0	1	1
Polyamine deacetylase HDAC10	0	3	0	3
Histone deacetylase 11	0	3	0	3
Histone deacetylase 8	0	3	0	3
Tyrosyl-DNA phosphodiesterase 1	0	2	0	2
Histone deacetylase 6	0	3	0	3
Histone deacetylase 9	0	3	0	3
Histone deacetylase 5	0	3	0	3
Chain A, Beta-lactamase	7	0	0	7
thyroid hormone receptor beta isoform a	7	0	0	7
Vpr	1	0	0	1
Major prion protein	0	0	3	3
Sodium channel protein type 1 subunit alpha	0	2	0	2
Sodium channel protein type 2 subunit alpha	0	3	0	3
Sodium channel protein type 3 subunit alpha	0	2	0	2
Frizzled-8	0	0	1	1
P2X purinoceptor 4	0	1	0	1
Solute carrier family 22 member 5	0	0	0	1
Solute carrier family 22 member 5	0	0	0	1
Solute carrier family 22 member 16	0	0	0	1
Solute carrier family 22 member 21	0	0	0	1
Solute carrier family 22 member 5	0	0	0	1
Angiopoietin-1 receptor	0	0	1	1
Histamine H4 receptor	0	2	1	3
interleukin 8	2	0	0	2
GALC protein	4	0	0	4
thioredoxin glutathione reductase	4	0	0	4
caspase 7, apoptosis-related cysteine protease	5	0	0	5
bromodomain adjacent to zinc finger domain 2B	8	0	0	8
caspase-3	5	0	0	5
FAD-linked sulfhydryl oxidase ALR	0	0	0	2
urokinase-type plasminogen activator precursor	6	0	0	6
plasminogen precursor	6	0	0	6
urokinase plasminogen activator surface receptor precursor	6	0	0	6
Carbonic anhydrase 12	0	3	0	5
Cytochrome P450 2D6	0	7	0	8
Nuclear receptor ROR-gamma	5	0	0	5
Carbonic anhydrase 9	0	3	0	6
Solute carrier organic anion transporter family member 1B3	0	4	0	5
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Putative Glycine Betaine-binding Abc Transporter Protein	0	0	1	1
Chain A, PUTATIVE GLYCINE BETAINE-BINDING ABC TRANSPORTER PROTEIN	0	0	1	1
Chain A, Glycine betaine/carnitine/choline-binding protein	0	0	1	1
Chain A, Glycine betaine/carnitine/choline-binding protein	0	0	1	1
Chain A, Glycine betaine/carnitine/choline-binding protein	0	0	1	1
Chain A, Glycine betaine/carnitine/choline-binding protein	0	0	1	1
Chain A, Choline-binding protein	0	0	1	1
Solute carrier family 22 member 1	0	1	0	2
Solute carrier family 22 member 2	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-3	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-2	0	1	0	1
Neuronal acetylcholine receptor subunit beta-3	0	1	0	1
Neuronal acetylcholine receptor subunit beta-4	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-5	0	1	0	1
Acetylcholinesterase	0	5	1	8
Sodium- and chloride-dependent creatine transporter 1	0	1	0	1
Choline O-acetyltransferase	0	0	0	1
Neuronal acetylcholine receptor subunit alpha-6	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-9	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-7	0	1	0	1
High affinity choline transporter 1	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-10	0	1	0	1
Beta-1 adrenergic receptor	0	1	0	1
Adenylate cyclase type 1	0	2	0	2
DNA polymerase beta	3	0	0	3
short transient receptor potential channel 6 isoform 1	0	0	1	1
transient receptor potential cation channel subfamily V member 1	2	0	0	2
Calmodulin-1	0	1	0	1
Beta-2 adrenergic receptor	0	4	0	4
Beta-1 adrenergic receptor	0	2	0	2
Endothelin receptor type B	0	1	0	1
Adenylate cyclase type 3	0	2	0	2
5-hydroxytryptamine receptor 3A	0	2	0	2
Endothelin receptor type B	0	1	0	1
Adenosine receptor A1	0	3	0	4
Beta-3 adrenergic receptor	0	2	0	2
Adenylate cyclase type 2	0	2	0	2
Adenylate cyclase type 4	0	2	0	2
5-hydroxytryptamine receptor 2C	0	3	0	3
5-hydroxytryptamine receptor 2A	0	2	0	2
Adenylate cyclase type 8	0	2	0	2
5-hydroxytryptamine receptor 5A	0	1	0	1
D(2) dopamine receptor	0	2	0	2
D(3) dopamine receptor	0	2	0	2
Gastrin/cholecystokinin type B receptor	0	2	0	2
D(2) dopamine receptor	0	2	0	2
Calmodulin	0	0	1	1
5-hydroxytryptamine receptor 2B	0	2	0	2
Adenylate cyclase type 6	0	2	0	2
Adenylate cyclase type 5	0	2	0	2
5-hydroxytryptamine receptor 4	0	2	0	2
Transporter	0	3	0	3
Cholecystokinin receptor type A	0	2	0	2
5-hydroxytryptamine receptor 1A	0	1	0	1
Adenylyl cyclase 7	0	2	0	2
Transporter	0	9	0	9
Chain A, CHIMERA OF IG KAPPA CHAIN: HUMAN CONSTANT REGION AND MOUSE VARIABLE REGION	0	0	1	1
Chain B, CHIMERA OF IG GAMMA-1 CHAIN: HUMAN CONSTANT REGION AND MOUSE VARIABLE REGION	0	0	1	1
Chain H, Fab M82G2, Heavy chain	0	0	1	1
Chain L, Fab M82G2, Light chain	0	0	1	1
Chain H, Fab M82g2, Heavy Chain	0	0	1	1
Chain L, Fab M82g2, Light Chain	0	0	1	1
Gamma-aminobutyric acid receptor subunit pi	0	1	0	1
Gamma-aminobutyric acid receptor subunit delta	0	1	0	1
Fatty acid-binding protein, heart	0	1	0	1
Muscarinic acetylcholine receptor M2	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-1	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-1	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-2	0	1	0	1
Liver carboxylesterase 1	0	1	0	2
cAMP-specific 3',5'-cyclic phosphodiesterase 4A	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-3	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-5	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-3	0	1	0	1
Lysosomal Pro-X carboxypeptidase	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-2	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-2	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-4	0	1	0	1
Gamma-aminobutyric acid receptor subunit epsilon	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4B	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4D	0	2	0	2
Leukotriene B4 receptor 1	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-6	0	1	0	1
Sodium-dependent dopamine transporter	0	3	0	3
Gamma-aminobutyric acid receptor subunit gamma-1	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-3	0	1	0	1
Leukotriene B4 receptor 2	0	1	0	1
Gamma-aminobutyric acid receptor subunit theta	0	1	0	1
Sodium- and chloride-dependent creatine transporter 1	0	1	0	1
Proton-coupled amino acid transporter 1	0	3	0	4
importin subunit beta-1 isoform 1	6	0	0	6
snurportin-1	6	0	0	6
GTP-binding nuclear protein Ran isoform 1	2	0	0	2
Rap guanine nucleotide exchange factor 3	2	0	0	2
Glutathione S-transferase P	0	1	0	1
Alpha-tocopherol transfer protein	0	0	1	1
apical membrane antigen 1, AMA1	3	0	0	3
Lysine-specific demethylase 4A	0	1	0	1
Guanine nucleotide-binding protein G	5	0	0	5
Hypoxia-inducible factor 1-alpha	0	0	1	1
Methylcytosine dioxygenase TET2	0	1	0	1
Deoxyhypusine hydroxylase	0	1	0	1
endonuclease IV	2	0	0	2
polyunsaturated fatty acid lipoxygenase ALOX12	2	0	0	2
runt-related transcription factor 1 isoform AML1b	2	0	0	2
core-binding factor subunit beta isoform 2	2	0	0	2
DNA polymerase kappa isoform 1	13	0	0	13
Epidermal growth factor receptor	0	3	0	3
Glutamate receptor 1	2	2	1	5
Glutamate receptor 3	2	2	1	5
Glutamate receptor 4	2	2	1	5
Caspase-7	2	0	0	2
Nuclear receptor subfamily 1 group I member 2	0	0	5	5
Nuclear receptor subfamily 1 group I member 2	0	0	2	2
Chain A, Protein (peroxisome Proliferator Activated Receptor (ppar-delta))	0	1	0	1
histone-lysine N-methyltransferase 2A isoform 2 precursor	2	0	0	2
Prostaglandin G/H synthase 1	0	1	0	1
Trypsin	0	1	0	1
Cytochrome P450 1A2	0	2	0	3
Coagulation factor VII	0	1	0	1
Aromatase	0	1	0	1
Tissue factor	0	2	0	2
Retinoic acid receptor RXR-alpha	0	1	2	3
Peroxisome proliferator-activated receptor gamma	0	0	3	3
Prostaglandin G/H synthase 2	0	2	0	2
Oxoeicosanoid receptor 1	0	1	0	1
glp-1 receptor, partial	8	0	0	8
LMP1 [Human herpesvirus 4]	0	0	0	1
nuclear receptor coactivator 1 isoform 1 [Homo sapiens]	0	2	0	2
transactivating tegument protein VP16 [Human herpesvirus 1]	0	2	0	2
nuclear receptor coactivator 3 isoform a	0	2	0	2
Regulatory protein E2	0	0	1	1
ATP-dependent translocase ABCB1	0	1	0	1
Polyunsaturated fatty acid lipoxygenase ALOX15	0	3	0	3
DNA topoisomerase 2	0	0	0	1
ATP-dependent translocase ABCB1	0	1	0	1
Serum paraoxonase/arylesterase 1	0	2	0	2
Caspase-3	0	2	0	2
DNA topoisomerase 2-alpha	0	0	0	1
Tubulin beta-2B chain	0	1	0	1
Similar to alpha-tubulin isoform 1	0	1	0	1
Similar to alpha-tubulin isoform 1	0	1	0	1
Chain A, Dihydrofolate reductase	0	0	1	1
acid sphingomyelinase	2	0	0	2
Thymidylate synthase	0	4	0	4
Thymidylate synthase	0	3	0	3
Dihydrofolate reductase	0	4	3	7
Aldo-keto reductase family 1 member B1	0	2	0	2
Alpha-synuclein	2	0	0	2
Folylpolyglutamate synthase, mitochondrial	0	1	0	4
Solute carrier organic anion transporter family member 1A3	0	2	0	4
Folylpolyglutamate synthase, mitochondrial	0	1	0	4
Multidrug resistance associated protein	0	1	0	3
Menin	0	0	1	1
Lecithin retinol acyltransferase	0	1	0	1
30S ribosomal protein S6	0	1	0	1
30S ribosomal protein S7	0	1	0	1
50S ribosomal protein L15	0	1	0	1
50S ribosomal protein L10	0	1	0	1
50S ribosomal protein L11	0	1	0	1
50S ribosomal protein L7/L12	0	1	0	1
50S ribosomal protein L19	0	1	0	1
50S ribosomal protein L1	0	1	0	1
50S ribosomal protein L20	0	1	0	1
50S ribosomal protein L27	0	1	0	1
50S ribosomal protein L28	0	1	0	1
50S ribosomal protein L29	0	1	0	1
50S ribosomal protein L31	0	1	0	1
50S ribosomal protein L31 type B	0	1	0	1
50S ribosomal protein L32	0	1	0	1
50S ribosomal protein L33	0	1	0	1
50S ribosomal protein L34	0	1	0	1
50S ribosomal protein L35	0	1	0	1
50S ribosomal protein L36	0	1	0	1
30S ribosomal protein S10	0	1	0	1
30S ribosomal protein S11	0	1	0	1
30S ribosomal protein S12	0	1	0	1
30S ribosomal protein S13	0	1	0	1
30S ribosomal protein S16	0	1	0	1
30S ribosomal protein S18	0	1	0	1
30S ribosomal protein S19	0	1	0	1
30S ribosomal protein S20	0	1	0	1
30S ribosomal protein S2	0	1	0	1
30S ribosomal protein S3	0	1	0	1
30S ribosomal protein S4	0	1	0	1
30S ribosomal protein S5	0	1	0	1
30S ribosomal protein S8	0	1	0	1
30S ribosomal protein S9	0	1	0	1
50S ribosomal protein L13	0	1	0	1
50S ribosomal protein L14	0	1	0	1
50S ribosomal protein L16	0	1	0	1
50S ribosomal protein L23	0	1	0	1
30S ribosomal protein S15	0	1	0	1
50S ribosomal protein L17	0	1	0	1
50S ribosomal protein L21	0	1	0	1
50S ribosomal protein L30	0	1	0	1
50S ribosomal protein L6	0	1	0	1
30S ribosomal protein S14	0	1	0	1
30S ribosomal protein S17	0	1	0	1
30S ribosomal protein S1	0	1	0	1
50S ribosomal protein L18	0	1	0	1
Lethal factor	0	1	0	1
50S ribosomal protein L2	0	1	0	1
50S ribosomal protein L3	0	1	0	1
50S ribosomal protein L24	0	1	0	1
50S ribosomal protein L4	0	1	0	1
50S ribosomal protein L22	0	1	0	1
50S ribosomal protein L5	0	1	0	1
30S ribosomal protein S21	0	1	0	1
50S ribosomal protein L25	0	1	0	1
50S ribosomal protein L36 2	0	1	0	1
Protein Rev	0	0	1	1
Aminoglycoside 3'-phosphotransferase	0	0	0	1
Beta-galactosidase	0	1	0	1
Lipopolysaccharide heptosyltransferase 1	0	1	0	1
PA-I galactophilic lectin	0	0	1	1
Jacalin	0	0	1	1
Chain A, Beta-phosphoglucomutase	0	1	0	1
Chain A, Beta-phosphoglucomutase	0	1	0	1
Chain A, ACETYLCHOLINESTERASE	0	1	0	1
Chain A, Acetylcholinesterase	0	1	0	1
Acetylcholinesterase	0	5	1	7
Acetylcholinesterase	0	3	0	3
Cholinesterase	0	5	0	5
Vascular endothelial growth factor receptor 1	0	1	0	1
Acetylcholinesterase	0	3	0	3
Acetylcholinesterase	0	2	0	2
Delta-type opioid receptor	0	5	1	7
Vascular endothelial growth factor receptor 3	0	1	0	1
Vascular endothelial growth factor receptor 2	0	1	0	1
Acetylcholinesterase	0	2	0	2
Kappa-type opioid receptor	0	4	1	6
Prolyl endopeptidase	0	1	0	1
Small conductance calcium-activated potassium channel protein 3	0	1	0	1
Cholinesterase	0	5	0	6
Carboxylic ester hydrolase	0	3	0	3
Chain A, GLUTAMATE RECEPTOR SUBUNIT 2	0	1	0	1
Chain A, Glutamate Receptor Subunit 2	0	1	0	1
Chain B, Glutamate Receptor Subunit 2	0	1	0	1
Chain A, Slr1257 protein	0	0	1	1
Chain A, Glucosamine--fructose-6-phosphate aminotransferase [isomerizing]	0	1	0	1
beta-2 adrenergic receptor	1	0	0	1
peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	7	0	0	7
Metabotropic glutamate receptor 8	0	2	0	2
Glutathione reductase, mitochondrial	0	4	0	4
Bifunctional aspartokinase/homoserine dehydrogenase 1	0	1	0	1
ATP-citrate synthase	0	1	0	1
Glutamate receptor ionotropic, kainate 1	0	2	1	3
Metabotropic glutamate receptor 1	0	1	1	2
Metabotropic glutamate receptor 2	0	0	1	1
Metabotropic glutamate receptor 3	0	0	1	1
Metabotropic glutamate receptor 4	0	1	1	2
Metabotropic glutamate receptor 5	0	0	1	1
Metabotropic glutamate receptor 6	0	0	1	1
Metabotropic glutamate receptor 7	0	0	1	1
Glutamate receptor ionotropic, kainate 1	0	1	1	2
Metabotropic glutamate receptor 5	0	1	1	3
Glutamate receptor ionotropic, kainate 2	0	2	1	3
Glutamate receptor 1	0	2	1	3
Glutamate receptor 2	0	2	1	3
Glutamate receptor 3	0	1	1	2
Glutamate receptor ionotropic, kainate 3	0	2	0	2
Metabotropic glutamate receptor 8	0	0	1	1
Glutamate receptor 4	0	2	1	3
Excitatory amino acid transporter 3	0	0	0	1
Glutamate racemase	0	0	0	1
Metabotropic glutamate receptor 8	0	1	1	2
Fatty-acid amide hydrolase 1	0	1	0	1
Glutamate receptor ionotropic, kainate 4	0	2	0	2
Glutamate carboxypeptidase 2	0	1	0	1
Glutamate receptor ionotropic, kainate 2	0	1	1	2
Glutamate receptor ionotropic, kainate 3	0	1	0	1
Metabotropic glutamate receptor 7	0	1	1	3
Metabotropic glutamate receptor 3	0	1	1	3
Metabotropic glutamate receptor 4	0	1	1	3
Glutamate receptor ionotropic, kainate 5	0	1	0	1
Glutamate receptor ionotropic, kainate 5	0	2	0	2
Glutamate racemase	0	0	0	1
Prolyl 4-hydroxylase	0	1	0	1
Alpha-ketoglutarate-dependent dioxygenase FTO	0	1	0	1
Chain A, Hypoxanthine Phosphoribosyltransferase	0	1	0	1
Chain A, HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE	0	1	0	1
Chain A, HYPOXANTHINE-GUANINE PHOSPHORIBOSYLTRANSFERASE	0	0	1	1
Chain B, HYPOXANTHINE-GUANINE PHOSPHORIBOSYLTRANSFERASE	0	0	1	1
Chain A, HYPOXANTHINE-GUANINE PHOSPHORIBOSYLTRANSFERASE	0	0	1	1
Chain A, Xanthine phosphoribosyltransferase	0	0	1	1
Hypoxanthine-guanine phosphoribosyltransferase	0	1	0	1
Histidine triad nucleotide-binding protein 1	0	0	1	1
nonstructural protein 1	6	0	0	6
Cocaine esterase	0	2	0	2
Transient receptor potential cation channel subfamily V member 1	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1C	0	3	0	3
UDP-glucuronosyltransferase 1A9	0	1	0	3
Potassium channel subfamily K member 2	0	1	1	2
Vitamin D-binding protein	0	1	0	1
HLA class I histocompatibility antigen, A alpha chain	0	0	1	1
Integrin beta-1	0	1	0	1
Integrin alpha-4	0	1	0	1
Carbonyl reductase [NADPH] 1	0	0	0	1
C-8 sterol isomerase	0	1	0	1
Delta-type opioid receptor	0	5	2	7
Mu-type opioid receptor	0	5	2	7
Kappa-type opioid receptor	0	3	2	5
5-hydroxytryptamine receptor 2A	0	1	0	1
AP-2 complex subunit sigma	0	1	0	1
N-acetyltransferase Eis	0	2	0	2
TAR DNA-binding protein 43	6	0	0	6
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase	0	1	0	1
Calcitonin gene-related peptide type 1 receptor	0	1	0	1
Genome polyprotein	0	2	0	2
Sigma intracellular receptor 2	0	1	0	1
Sigma intracellular receptor 2	0	3	0	3
Zinc finger protein 664	0	1	0	1
Vesicular acetylcholine transporter	0	1	0	1
Transient receptor potential cation channel subfamily V member 4	0	1	0	1
Transient receptor potential cation channel subfamily V member 2	0	1	0	1
N(G),N(G)-dimethylarginine dimethylaminohydrolase 1	0	2	0	2
Snq2p	0	0	0	1
Sodium-dependent noradrenaline transporter	0	1	0	1
Solute carrier family 22 member 3	0	2	0	2
Prostaglandin G/H synthase 1	0	2	0	2
Sphingomyelin phosphodiesterase	0	1	0	1
Pleiotropic ABC efflux transporter of multiple drugs	0	1	0	2
Envelope glycoprotein	0	0	1	1
Sodium-dependent serotonin transporter	0	1	0	1
Amine oxidase [flavin-containing] A	0	1	0	1
Amine oxidase [flavin-containing] A	0	1	0	1
Amine oxidase [flavin-containing] B	0	1	0	1
C-X-C chemokine receptor type 3	0	1	0	1
Chymotrypsinogen A	0	1	0	1
GTP-binding protein (rab7)	0	0	1	1
ras protein, partial	0	0	1	1
Rac1 protein	0	0	1	1
cell division cycle 42 (GTP binding protein, 25kDa), partial	0	0	1	1
Albumin	0	1	0	1
Seed linoleate 13S-lipoxygenase-1	0	1	0	1
Fatty acid-binding protein, intestinal	0	1	0	1
Prostaglandin G/H synthase 1	0	1	0	1
Caspase-1	0	1	0	1
Prostaglandin G/H synthase 2	0	2	0	2
Caspase-4	0	1	0	1
Caspase-5	0	1	0	1
Caspase-9	0	1	0	1
Ras-related protein Rab-2A	0	0	1	1
Lactoylglutathione lyase	0	1	0	1
Solute carrier family 22 member 7	0	1	0	1
Potassium voltage-gated channel subfamily E member 1	0	1	0	1
Potassium voltage-gated channel subfamily KQT member 1	0	1	0	1
Chain A, AMINOPEPTIDASE	0	1	0	1
Chain A, AMINOPEPTIDASE	0	1	0	1
Chain A, Leucine Aminopeptidase	0	1	0	1
Intestinal-type alkaline phosphatase	0	2	0	2
Large neutral amino acids transporter small subunit 1	0	4	0	4
Phospholipase A-2-activating protein	0	2	0	2
dopamine D1 receptor	3	0	0	3
WRN	1	0	0	1
integrase, partial	0	1	0	1
lens epithelium-derived growth factor p75	0	1	0	1
pyruvate kinase	2	0	0	2
hexokinase-4 isoform 1	2	0	0	2
glucokinase regulatory protein	2	0	0	2
DNA polymerase eta isoform 1	3	0	0	3
Polyphenol oxidase 2	0	1	0	2
Plasma kallikrein	0	0	0	2
Tyrosine-protein kinase Lck	0	1	1	2
Tyrosine-protein kinase Fyn	0	1	0	1
Carbonic anhydrase 3	0	1	0	3
Tyrosinase	0	1	0	1
Carbonic anhydrase 4	0	0	0	2
Carbonic anhydrase 6	0	2	0	4
Adenosine receptor A2a	0	1	0	2
Carbonic anhydrase 5A, mitochondrial	0	1	0	3
Carbonic anhydrase	0	0	0	2
Carbonic anhydrase 7	0	1	0	3
Solute carrier family 15 member 1	0	4	0	5
Carbonic anhydrase	0	1	0	3
SLC16A10 protein	0	0	0	2
Carbonic anhydrase	0	1	0	3
Carbonic anhydrase	0	0	0	2
Carbonic anhydrase	0	1	0	3
Carbonic anhydrase	0	1	0	3
Monocarboxylate transporter 10	0	0	0	2
Carbonic anhydrase 15	0	1	0	3
Carbonic anhydrase 13	0	1	0	4
Carbonic anhydrase 14	0	0	0	2
Carbonic anhydrase 5B, mitochondrial	0	1	0	3
phosphoglycerate kinase	1	0	0	1
inositol monophosphatase 1	1	0	0	1
Cholecystokinin receptor type A	1	0	0	1
Gastrin/cholecystokinin type B receptor	1	0	0	1
Glycogen synthase kinase-3 beta	0	1	1	2
Chain A, Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplast	0	1	0	1
Chain A, Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplast	0	1	0	1
Chain B, DIHYDROFOLATE REDUCTASE	0	0	1	1
Chain B, DIHYDROFOLATE REDUCTASE	0	0	1	1
Chain B, DIHYDROFOLATE REDUCTASE	0	0	1	1
ClpP	1	0	0	1
Thymidylate synthase	0	1	0	1
Thymidylate synthase	0	1	0	1
caspase-1 isoform alpha precursor	1	0	0	1
Toll-like receptor 4	0	1	0	1
Fatty-acid amide hydrolase 1	0	2	0	2
ATP-binding cassette sub-family C member 3	0	1	0	2
Dihydrofolate reductase	0	5	0	6
Dihydrofolate reductase	0	2	0	3
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	2	0	3
Thymidylate synthase	0	1	0	1
Tyrosine-protein kinase ABL1	0	1	1	2
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
High mobility group protein B1	0	0	1	1
Dihydrofolate reductase	0	1	0	1
Thymidylate synthase	0	1	0	1
Glucose-6-phosphate 1-dehydrogenase	0	2	0	2
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Folate receptor beta	0	1	0	1
Cytochrome P450 11B1, mitochondrial	0	1	0	1
Folate receptor alpha	0	1	0	1
Dihydrofolate reductase	0	2	0	2
Histidine decarboxylase	0	1	1	2
Trifunctional purine biosynthetic protein adenosine-3	0	1	0	1
Cyclin-dependent kinase 2	0	0	1	1
Bifunctional purine biosynthesis protein ATIC	0	2	0	2
Multidrug resistance-associated protein 1	0	0	0	1
Reduced folate transporter	0	2	0	2
6-phosphogluconate dehydrogenase, decarboxylating	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Pteridine reductase 1	0	3	0	3
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Canalicular multispecific organic anion transporter 1	0	1	0	2
Trifunctional purine biosynthetic protein adenosine-3	0	1	0	1
Solute carrier family 22 member 20	0	2	0	2
Dihydrofolate reductase	0	1	0	1
Solute carrier family 22 member 6	0	2	0	2
Dihydrofolate reductase	0	1	0	1
ATP-binding cassette sub-family C member 11	0	0	0	1
Proton-coupled folate transporter	0	1	0	1
Solute carrier family 22 member 11	0	0	0	1
Protein-arginine deiminase type-4	0	1	0	1
Broad substrate specificity ATP-binding cassette transporter ABCG2	0	3	0	4
histone deacetylase 9 isoform 3	2	0	0	2
nuclear receptor subfamily 1, group I, member 2	3	0	0	3
Glucocorticoid receptor	0	6	2	13
Glycine receptor subunit alpha-1	0	6	0	6
Androgen receptor	0	3	0	3
Glycine receptor subunit beta	0	6	0	6
Glycine receptor subunit alpha-2	0	6	0	6
Glycine receptor subunit alpha-3	0	6	0	6
Type-2 angiotensin II receptor	0	1	0	1
Angiotensin-converting enzyme	0	1	0	1
Indoleamine 2,3-dioxygenase 1	0	2	0	3
Rap guanine nucleotide exchange factor 4	2	0	0	2
Kappa-type opioid receptor	0	1	0	2
Mu-type opioid receptor	0	1	0	2
Mu-type opioid receptor	0	3	1	4
UDP-glucuronosyltransferase 1A8	0	0	0	1
thyrotropin-releasing hormone receptor	1	0	0	1
Cholesteryl ester transfer protein	0	1	0	1
D-amino-acid oxidase	0	1	0	1
Xanthine dehydrogenase/oxidase	0	1	0	1
Hydroxycarboxylic acid receptor 3	0	0	1	1
Nicotinamidase	0	1	0	1
Hydroxycarboxylic acid receptor 2	0	0	1	1
Hydroxycarboxylic acid receptor 2	0	2	1	3
D-aspartate oxidase	0	1	0	1
Hydroxycarboxylic acid receptor 2	0	1	1	2
Parkin	2	0	0	2
Voltage-dependent L-type calcium channel subunit beta-4	0	1	0	1
Voltage-dependent P/Q-type calcium channel subunit alpha-1A	0	1	0	1
Voltage-dependent T-type calcium channel subunit alpha-1G	0	1	0	1
Voltage-dependent calcium channel gamma-3 subunit	0	1	0	1
Voltage-dependent T-type calcium channel subunit alpha-1H	0	1	0	1
Adenosine receptor A3	0	1	0	1
Cannabinoid receptor 1	0	2	0	2
Voltage-dependent L-type calcium channel subunit beta-3	0	1	0	1
Voltage-dependent calcium channel subunit alpha-2/delta-1	0	1	0	1
Voltage-dependent calcium channel gamma-7 subunit	0	1	0	1
Voltage-dependent L-type calcium channel subunit beta-1	0	1	0	1
Voltage-dependent calcium channel gamma-1 subunit	0	1	0	1
Voltage-dependent L-type calcium channel subunit beta-2	0	1	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C	0	1	0	1
Voltage-dependent R-type calcium channel subunit alpha-1E	0	1	0	1
Voltage-dependent calcium channel subunit alpha-2/delta-4	0	1	0	1
Transient receptor potential cation channel subfamily A member 1	0	0	1	1
Voltage-dependent calcium channel subunit alpha-2/delta-3	0	1	0	1
Voltage-dependent calcium channel gamma-8 subunit	0	1	0	1
Bile acid receptor	0	2	0	2
Voltage-dependent calcium channel gamma-6 subunit	0	1	0	1
Voltage-dependent calcium channel subunit alpha-2/delta-2	0	1	0	1
Voltage-dependent T-type calcium channel subunit alpha-1I	0	1	0	1
Voltage-dependent calcium channel gamma-4 subunit	0	1	0	1
Voltage-dependent calcium channel gamma-5 subunit	0	1	0	1
Voltage-dependent calcium channel gamma-2 subunit	0	1	0	1
Glyceraldehyde-3-phosphate dehydrogenase	0	1	0	1
DNA repair protein RAD52 homolog	0	1	0	1
Sodium/potassium-transporting ATPase subunit alpha-1	0	1	0	1
Sodium/potassium-transporting ATPase subunit beta-1	0	1	0	1
Sodium/potassium-transporting ATPase subunit alpha-3	0	1	0	1
Sodium/potassium-transporting ATPase subunit beta-2	0	1	0	1
Indoleamine 2,3-dioxygenase 1	0	1	0	1
Fatty acid synthase	0	2	0	2
Sodium/potassium-transporting ATPase subunit alpha-2	0	1	0	1
Sodium/potassium-transporting ATPase subunit beta-3	0	1	0	1
Sodium/potassium-transporting ATPase subunit gamma	0	1	0	1
Sodium/potassium-transporting ATPase subunit alpha-4	0	1	0	1
Indoleamine 2,3-dioxygenase 2	0	1	0	1
Muscarinic acetylcholine receptor DM1	0	2	0	2
Xaa-Pro dipeptidase	0	0	0	1
Cystathionine gamma-lyase	0	1	0	1
Succinyl-diaminopimelate desuccinylase	0	1	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Metallo-beta-lactamase type 2	0	0	0	1
Metallo-beta-lactamase VIM-11	0	0	0	1
Beta-lactamase	0	0	0	1
Metallo-beta-lactamase VIM-2	0	0	0	1
Beta-lactamase	0	0	0	1
Metallo-beta-lactamase VIM-19	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Metallo-beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
streptokinase A precursor	0	0	1	1
Beta-lactamase	0	0	0	1
Solute carrier family 22 member 8	0	1	0	2
Beta-lactamase	0	0	0	1
Beta-lactamase 1	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase SHV-1	0	0	0	1
Beta-lactamase SHV-1	0	0	0	1
Beta-lactamase OXA-10	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase TEM	0	1	0	2
Beta-lactamase	0	0	0	1
B2 metallo-beta-lactamase	0	0	0	1
Solute carrier family 15 member 2	0	1	0	1
Metallo-beta-lactamase VIM-13	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Efflux transporter	0	0	0	1
Beta-lactamase	0	0	0	1
Metallo-beta-lactamase VIM-2	0	0	0	1
Beta-lactamase Toho-1	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Class D beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Solute carrier family 15 member 2	0	2	0	2
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Metallo-b-lactamase	0	0	0	1
Beta-lactamase IMP-1	0	0	0	1
BlaVIM-1	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Carbapenem-hydrolyzing beta-lactamase KPC	0	0	0	1
Beta-lactamase class B VIM-2	0	0	0	1
Beta-lactamase	0	0	0	1
Solute carrier family 22 member 8	0	1	0	2
Beta-lactamase VIM-1	0	0	0	1
Chain A, TRIOSEPHOSPHATE ISOMERASE	0	1	0	1
Chain A, METHYLGLYOXAL SYNTHASE	0	1	0	1
Chain F, METHYLGLYOXAL SYNTHASE	0	1	0	1
Chain A, TRIOSEPHOSPHATE ISOMERASE	0	1	0	1
Chain B, TRIOSEPHOSPHATE ISOMERASE	0	1	0	1
Chain A, triosephosphate isomerase, glycosomal	0	1	0	1
Chain A, Triosephosphate Isomerase	0	1	0	1
Chain B, Triosephosphate Isomerase	0	1	0	1
Chain A, Triosephosphate Isomerase	0	1	0	1
Chain A, Enolase	0	1	0	1
Chain A, Methylglyoxal synthase	0	1	0	1
Chain F, Methylglyoxal synthase	0	1	0	1
Chain A, Triosephosphate Isomerase	0	1	0	1
Ornithine transcarbamylase, mitochondrial	0	1	0	1
Nociceptin receptor	0	1	0	1
Fe(3+)-Zn(2+) purple acid phosphatase	0	1	0	1
Acetylcholinesterase	0	1	0	1
Cholinesterase	0	1	0	1
Acyl-CoA:cholesterol acyltransferase	0	1	0	1
Carboxylic ester hydrolase	0	1	0	1
Hsf1 protein	0	0	1	2
Synaptic vesicle glycoprotein 2A	0	1	0	1
Muscarinic acetylcholine receptor M1	0	1	0	1
Muscarinic acetylcholine receptor M4	0	1	0	1
Muscarinic acetylcholine receptor	0	1	0	1
Muscarinic acetylcholine receptor M5	0	1	0	1
Muscarinic acetylcholine receptor M3	0	1	0	1
Muscarinic acetylcholine receptor M2	0	1	0	1
luciferase	0	0	0	1
Fatty acid-binding protein, liver	0	1	0	1
Estrogen receptor	0	2	0	2
Progesterone receptor	0	2	0	3
Glucocorticoid receptor	0	1	1	2
Glucocorticoid receptor	0	0	1	1
Corticosteroid-binding globulin	0	1	0	1
Mineralocorticoid receptor	0	2	1	3
Androgen receptor	0	2	0	2
Glutamine synthetase	0	0	1	1
Nociceptin receptor	0	0	1	1
Estrogen receptor beta	0	2	0	2
pregnane X receptor	4	0	0	4
heat shock protein HSP 90-alpha isoform 2	0	0	0	1
heat shock protein 90, putative	0	0	0	1
NPC intracellular cholesterol transporter 1 precursor	1	0	0	1
pyruvate kinase PKM isoform b	1	0	0	1
Ornithine decarboxylase	1	0	0	1
Pyruvate kinase PKM	0	0	1	1
Neutral amino acid transporter A	0	1	0	1
Neutral amino acid transporter B(0)	0	1	0	1
Amino acid transporter	0	1	0	1
Carbonic anhydrase	0	0	0	1
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase	0	1	0	1
Beta-carbonic anhydrase 1	0	1	0	1
Carbonic anhydrase 2	0	1	0	1
Carbonic anhydrase, alpha family	0	1	0	1
Carbonic anhydrase	0	1	0	1
Delta carbonic anhydrase	0	1	0	1
D(2) dopamine receptor	0	1	0	1
Cytochrome P450 3A5	0	1	0	1
Serine/threonine-protein kinase mTOR	0	1	0	1
Peptidyl-prolyl cis-trans isomerase FKBP1A	0	2	1	3
Peptidyl-prolyl cis-trans isomerase FKBP1B	0	0	1	1
Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform	0	1	0	1
Peptidyl-prolyl cis-trans isomerase FKBP5	0	1	0	1
Splicing factor 3B subunit 3	0	1	0	1
Solute carrier organic anion transporter family member 1B1	0	1	0	2
polyadenylate-binding protein 1	0	1	0	1
Tyrosine-protein kinase ABL2	0	1	0	1
Chain A, ykoF	0	0	1	1
Chain B, ykoF	0	0	1	1
Chain A, ThiT	0	0	1	1
Thiamine transporter ThiT	0	0	1	1
Transketolase	0	0	1	1
Thiamine-binding periplasmic protein	0	0	1	1
Chain X, Thyroid hormone receptor beta-1	0	0	1	1
Chain X, Thyroid hormone receptor beta-1	0	0	1	1
serine/threonine-protein kinase PLK1	1	0	0	1
Solute carrier organic anion transporter family member 1A4	0	0	0	1
Solute carrier organic anion transporter family member 1A5	0	0	0	1
Transthyretin	0	1	0	2
Thyroid hormone receptor alpha	0	0	1	1
Thyroid hormone receptor beta	0	0	1	1
Proliferating cell nuclear antigen	0	1	0	1
Malate dehydrogenase, mitochondrial	0	1	0	1
Solute carrier organic anion transporter family member 1A2	0	0	0	1
Solute carrier organic anion transporter family member 4C1	0	1	0	1
Monocarboxylate transporter 8	0	0	0	1
Solute carrier organic anion transporter family member 1C1	0	0	0	1
Chain A, CARBONIC ANHYDRASE II	0	1	0	1
Chain A, Trp Rna-binding Attenuation Protein	0	0	1	1
Chain K, Trp Rna-binding Attenuation Protein	0	0	1	1
Chain B, tryptophanyl-tRNA synthetase	0	0	1	1
Chain C, Tryptophanyl-tRNA synthetase II	0	0	1	1
Myeloperoxidase	0	1	0	1
Stromelysin-1	0	1	0	1
Substance-P receptor	0	1	0	1
Tryptophan 2,3-dioxygenase	0	1	0	2
Uracil nucleotide/cysteinyl leukotriene receptor	0	1	0	1
Tryprostatin B synthase	0	0	0	1
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase	0	0	1	1
Solute carrier family 15 member 1	0	1	0	1
Valacyclovir hydrolase	0	0	0	1
Chain A, Arginase 1	0	1	0	1
Aldo-keto reductase family 1 member A1	0	1	0	1
Aldo-keto reductase family 1 member A1	0	1	0	1
Aldo-keto reductase family 1 member A1	0	1	0	1
Aldo-keto reductase family 1 member B7	0	1	0	1
NAD-dependent protein deacylase sirtuin-5, mitochondrial	0	1	0	1
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Synonyms(1)

Research

Studies (262)

Protein Targets (1,150)

Apraxias

Synonyms(1)

Research

Studies (262)

Drugs Studied (146)

Protein Targets (1,150)