Page last updated: 2024-09-27

Pseudohypoparathyroidism

A hereditary syndrome clinically similar to HYPOPARATHYROIDISM. It is characterized by HYPOCALCEMIA; HYPERPHOSPHATEMIA; and associated skeletal development impairment and caused by failure of response to PARATHYROID HORMONE rather than deficiencies. A severe form with resistance to multiple hormones is referred to as Type 1a and is associated with maternal mutant allele of the ALPHA CHAIN OF STIMULATORY G PROTEIN.

Synonyms(1)

Synonym
Pseudohypoparathyroidism

Research Excerpts

Overview

ExcerptReference
"A case of pseudohypoparathyroidism is described, finding in addition to the typical clinical data described in the literature an all almost total atrophy of the minor lips and clitoris, a perforated hymen and a "paradoxical" increase of convulsions with anticomicial treatment."( Guerrero, J; Hervás, F; Quesada, JM; Vázquez, C, 1981)
"Pseudohypoparathyroidism is an inherited disorder associated with resistance to the action of several hormones, including parathyroid hormone, thyroid-stimulating hormone, follicle-stimulating hormone, and luteinizing hormone."( Aurbach, GD; Breslau, NA; Downs, RW; Lasker, RD; Levine, MA; Marx, SJ; Moses, AM; Spiegel, AM, 1982)
"The diagnosis of pseudohypoparathyroidism is often not made until many years after the onset of symptoms and signs characteristic of the disease."( Frederiksen, PK; Jacobsen, JG, 1980)
"Three types of pseudohypoparathyroidism are known according to the site in which the disorder is localized, within the complex formed by the cell receptor for the hormone and the adenylate cyclase systems of the cell membrane: Ia, Ib and II."( Lucas, A; Pizarro, E; Reverter, JL; Rius, F; Salinas, I, 1993)
"Type la pseudohypoparathyroidism is due to a molecular defect causing Gs protein deficiency."( Boisson Lesage, C; Carel, JC; Chaussain, JL; Coutant, R; Garabédian, M; Mathivon, L; Renier, D, 1997)
"Pseudohypoparathyroidism is a group of diseases characterized by renal resistance to parathyroid hormone."( Eubanks, PJ; Stabile, BE, 1998)
"Pseudohypoparathyroidism is a congenital metabolic disorder which is often revealed by growth retardation."( Adamsbaum, C; Garabedian, M; Hamidou, A; Kalifa, G; Merzoug, V, 1999)
"Pseudopseudohypoparathyroidism is defined by Albright's osteodystrophy without resistance to PTH."( Vlaeminck-Guillem, V; Wémeau, JL, 1999)
"Pseudohypoparathyroidism is a very rare condition and systolic LV dysfunction for which hypocalcaemia is responsible, would seem to be totally reversible after calcium supplementation."( Baille, N; Dusselier, L; Massing, JL; Weber, E; Zakari, I, 2000)
"Pseudohypoparathyroidism is a hereditary condition in people that, to our knowledge, has not been identified in ferrets previously and is caused by a lack of response to high serum parathyroid hormone concentrations, rather than a deficiency of this hormone."( Greenacre, CB; Greene, CE; Wilson, GH, 2003)
"Pseudohypoparathyroidism is characterized by a resistance to parathormone, with variable phenotypical and biochemical manifestations."( Carrasco, CM; López, JM, 2004)
"Pseudohypoparathyroidism is rare sporadic or autosomal dominant disorder having several subtypes (type Ia, Ib, Ic, type II)."( Hoque, MA; Islam, MN; Kader, SA, 2011)
"Pseudohypoparathyroidism is characterized by parathormone (PTH) resistance, high PTH levels and hypocalcemia which need to be corrected with calcium and vitamin D supplementation."( Calvo, L; Corrias, A; de Sanctis, L; Feyles, F; Mussa, A; Peiretti, V; Santanera, A; Tessaris, D, 2014)
"Pseudohypoparathyroidism is a rare genetic disease characterized by hypocalcaemia and hyperphosphataemia due to the defect to the guanine nucleotide-binding protein alpha subunit (GNAS) gene."( Dong, A; Guo, X; Lu, D; Zhang, J, 2021)
"Pseudopseudohypoparathyroidism is an imprinted GNAS spectrum disorder that induces the phenotype of Albright's hereditary osteodystrophy."( Brokamp, G; Mosser-Goldfarb, J, 2022)

Context

ExcerptReference
"Several forms of pseudohypoparathyroidism have been recognized, each representing a defect as a different site of PTH action."( Schneider, AB; Sherwood, LM, 1975)
"A case of pseudohypoparathyroidism has been investigated."( Crabbé, J; Devogelaer, JP; Docquier, C; Nagant de Deuxchaisnes, C, 1979)
"Pseudohypoparathyroidism has further been subdivided into types Ia, Ib, Ic, and II."( Eubanks, PJ; Stabile, BE, 1998)

Treatment

ExcerptReference
"Recommendations for diagnosis and treatment of pseudohypoparathyroidism and related disorders: an updated practical tool for physicians and patients."( Konan, VK; Mathias, NJ; S, P, 2023)

Research

Studies (637)

TimeframeStudies, This Condition (%)All Conditions %
pre-1990430 (67.50)23.3326
1990's66 (10.36)12.5806
2000's57 (8.95)18.1394
2010's61 (9.58)28.8240
2020's23 (3.61)9.53
DrugIndicatedRelationship StrengthStudiesTrials
hydrochloric acid0low10
salicylic acid0low10
creatine0low40
lactic acid0low20
glycine0low10
glycerol0low10
hydrogen carbonate0low50
iodine0low20
orotic acid0low10
thiosulfates0low20
sulfites0low20
uric acid0low30
urea0low20
phenytoin0low20
acetazolamide0low70
chlorothiazide0low10
chlorpromazine0low10
chlorpropamide0low10
chlorthalidone0low10
cimetidine0low10
valproic acid0low10
etidronate0low10
furosemide0low10
hydrochlorothiazide0low20
1-methyl-3-isobutylxanthine0low10
isoproterenol0low70
metoclopramide0low10
mitotane0low10
nifedipine0low10
phenobarbital0low30
pindolol0low10
probenecid0low40
propranolol0low10
sodium fluoride0low20
thalidomide0low10
tolazamide0low10
tolbutamide0low20
corticosterone0low10
prednisolone0low10
hydroxyproline0medium51
thyroxine0low170
spironolactone0low10
aldosterone0low60
penicillamine0low10
prednisone0low10
triiodothyronine0low80
glutamine0low10
sucrose0low10
ethinyl estradiol0low10
adenosine diphosphate0low10
galactose0low10
levodopa0low10
edetic acid0medium71
adenosine monophosphate0low40
methionine0low10
arginine0medium31
thiophenes0low10
pyrazines0low10
nitroblue tetrazolium0low20
calcium gluconate0low50
chlormadinone acetate0low10
limestone0low70
dihydrotestosterone0low10
copper gluconate0low30
calcium lactate0low20
amiloride0low10
dithiothreitol0low10
floxacillin0low10
silver0low10
technetium0low20
magnesium sulfate0low20
tricalcium phosphate0low10
sodium thiosulfate0low20
fluorine0low10
ammonium chloride0medium11
fluorides0low20
adenosine diphosphate ribose0low30
diltiazem0low10
1-carboxyglutamic acid0low10
colforsin0low20
cobalt0low10
hydrogen sulfite0low20
sr1417160low10
pyridinoline0medium11
deoxypyridinoline0medium11
cinacalcet0low30
angiotensin ii0low30
aceglutamide0low10
glycogen0low10
diethylstilbestrol0low10
sodium bicarbonate0medium11
glycosides0low10
isomethyleugenol0low50
arginine vasopressin0low20
pyrophosphate0low30
methimazole0low10
tamoxifen0low10
nadp0low10
17-ketosteroids0low10
calcitriol0medium762
vitamin k semiquinone radical0low10
alprostadil0low20
vitamin d 20medium201
cholecalciferol0medium292
phenylephrine hydrochloride0low10
acitretin0low10
cyproterone0low10
iloprost0low10
aluminum0low20
cysteine0low10
phosphorus0medium891
25-hydroxyvitamin d 20low20
oxalates0low10
24,25-dihydroxyvitamin d 30low10
5-phenylpent-4-enyl-1-hydroperoxide0low10
pentagastrin0low50
pituitrin0low60
dihydrotachysterol0low270
acid phosphatase0medium21
nad0low30
glucagon0low100
incretins0low10
menotropins0low10
technetium tc 99m sestamibi0low10
bucladesine0low110
sodium pertechnetate tc 99m0low10
triiodothyronine, reverse0low10
glycolipids0low10
piperidines0low10
natriuretic peptide, brain0low20
hyaluronoglucosaminidase0low10
exudates0low10
cyclic gmp0low40
guanosine diphosphate0low20
guanosine triphosphate0low100
guanosine 5'-o-(3-thiotriphosphate)0low20
guanylyl imidodiphosphate0low10
eye0low10
leptin0low10

Protein Targets (1,226)

ProteinPotency MeasurementsInhibition MeasurementsActivation MeasurementsDrugs
Chain A, High-affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A0101
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4D0101
Chain A, Phosphodiesterase 9A0101
Chain A, JmjC domain-containing histone demethylation protein 3A110011
Chain A, Class I phosphodiesterase PDEB10101
Chain A, High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A0101
Chain A, cGMP-dependent 3',5'-cyclic phosphodiesterase0101
Chain A, cGMP-specific 3',5'-cyclic phosphodiesterase catalytic domain, Cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha chimera0101
Chain A, cGMP-specific 3',5'-cyclic phosphodiesterase catalytic domain, Cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha chimera0101
Chain A, High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A0101
Chain A, High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A0101
glp-1 receptor, partial100010
thyroid stimulating hormone receptor120012
estrogen-related nuclear receptor alpha390039
Phosphodiesterase 0404
mitogen-activated protein kinase 19009
geminin410041
cytochrome P450 3A4 isoform 1160016
histone acetyltransferase KAT2A isoform 1120012
cGMP-dependent 3',5'-cyclic phosphodiesterase0202
Gamma-aminobutyric acid receptor subunit pi164222
Monocarboxylate transporter 40101
High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A0101
cGMP-specific 3',5'-cyclic phosphodiesterase0303
High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A0101
Renin0404
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A 0202
cAMP-specific 3',5'-cyclic phosphodiesterase 4D 0202
cAMP-specific 3',5'-cyclic phosphodiesterase 4C0202
cAMP-specific 3',5'-cyclic phosphodiesterase 4B0202
Gamma-aminobutyric acid receptor subunit beta-1164222
Gamma-aminobutyric acid receptor subunit delta164222
Gamma-aminobutyric acid receptor subunit gamma-2164222
Gamma-aminobutyric acid receptor subunit alpha-5164222
Gamma-aminobutyric acid receptor subunit alpha-3164222
Gamma-aminobutyric acid receptor subunit gamma-1165223
Gamma-aminobutyric acid receptor subunit alpha-2164222
Adenosine receptor A10507
Gamma-aminobutyric acid receptor subunit alpha-4164222
Gamma-aminobutyric acid receptor subunit gamma-3164222
Adenosine receptor A30202
Adenosine receptor A2a011316
Adenosine receptor A2b0103
Adenosine receptor A2b0304
Gamma-aminobutyric acid receptor subunit alpha-6164222
Adenosine receptor A1010317
Adenosine receptor A2a0508
Sodium-dependent serotonin transporter0505
Adenosine receptor A2a0202
Cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha'0101
cAMP-specific 3',5'-cyclic phosphodiesterase 4A0202
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A0202
Gamma-aminobutyric acid receptor subunit alpha-1164222
Gamma-aminobutyric acid receptor subunit beta-3164222
Gamma-aminobutyric acid receptor subunit beta-2164222
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B0202
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B0202
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B0101
cAMP-specific 3',5'-cyclic phosphodiesterase 4B0404
cAMP-specific 3',5'-cyclic phosphodiesterase 4D0404
cGMP-inhibited 3',5'-cyclic phosphodiesterase B0303
Voltage-dependent L-type calcium channel subunit alpha-1C0809
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A0303
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C0303
cGMP-inhibited 3',5'-cyclic phosphodiesterase A0303
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C0101
Phosphodiesterase 0101
GABA theta subunit164222
Phosphodiesterase 0101
Gamma-aminobutyric acid receptor subunit epsilon164222
cAMP-specific 3',5'-cyclic phosphodiesterase 7B0101
nuclear receptor subfamily 1, group I, member 3220022
thyroid stimulating hormone receptor130013
Chain A, TYROSYL-DNA PHOSPHODIESTERASE100010
Chain A, CARBONIC ANHYDRASE II0011
Chain A, CARBONIC ANHYDRASE II0011
Chain A, CARBONIC ANHYDRASE II0011
Chain A, Carbonic Anhydrase Ii0011
Chain A, Carbonic Anhydrase Ii0011
Chain A, Beta-lactamase7007
Chain A, Endochitinase0101
Chain A, Endochitinase0101
Chain A, Endochitinase0101
Chain A, Class Iii Chitinase Chia10101
Chain A, Carbonic anhydrase 130101
Chain A, Carbonic anhydrase II0101
Chain A, Carbonic anhydrase 20101
Chain A, Carbonic anhydrase 20101
Chain A, Carbonic anhydrase 20101
Chain A, Carbonic anhydrase 20101
Chain A, Carbonic anhydrase 20101
Chain A, Carbonic anhydrase 20101
Chain A, Carbonic anhydrase 20101
Chain A, Carbonic anhydrase 20101
Chain A, Carbonic anhydrase 20101
Chain A, Carbonic anhydrase0101
Chain B, Carbonic anhydrase0101
Chain A, Carbonic anhydrase 20101
Carbonic anhydrase 0001
Carbonic anhydrase 0404
thioredoxin reductase210021
GALC protein3003
GLI family zinc finger 3300030
cytochrome P450 family 3 subfamily A polypeptide 4210021
glucocorticoid receptor [Homo sapiens]380038
retinoic acid nuclear receptor alpha variant 1320032
retinoid X nuclear receptor alpha260026
Carbonic anhydrase 0202
Carbonic anhydrase 0202
arylsulfatase A140014
Carbonic anhydrase0202
euchromatic histone-lysine N-methyltransferase 2390039
Bloom syndrome protein isoform 1100010
thyroid hormone receptor beta isoform a170017
nuclear factor erythroid 2-related factor 2 isoform 1340034
peripheral myelin protein 22250025
survival motor neuron protein isoform d150015
muscleblind-like protein 1 isoform 14004
ATP-binding cassette sub-family C member 3027027
Multidrug resistance-associated protein 4028030
Carbonic anhydrase0101
Solute carrier family 22 member 60909
Carbonic anhydrase 1207113
Prolyl endopeptidase0101
Carbonic anhydrase-related protein 110102
Bile salt export pump041041
Glycogen phosphorylase, muscle form0101
Carbonic anhydrase 1016125
Carbonic anhydrase 2019228
Carbonic anhydrase 20202
Cytochrome P450 1A20315
Carbonic anhydrase 306110
Cathepsin B0101
Cytochrome P450 3A4012116
Steryl-sulfatase0101
5-hydroxytryptamine receptor 2C0404
Polyunsaturated fatty acid 5-lipoxygenase0303
Cytochrome P450 2C80202
Cytochrome P450 2D60729
Cytochrome P450 2A60202
Cytochrome P450 2C9 014015
5-hydroxytryptamine receptor 2A0606
Androgen receptor015117
Translocator protein0123
Cannabinoid receptor 10325
Arachidonate 5-lipoxygenase-activating protein0101
Cytochrome P450 2B60303
Carbonic anhydrase 4011116
Carbonic anhydrase 607112
Carbonic anhydrase 5A, mitochondrial0101
Serum paraoxonase/arylesterase 10202
Dipeptidyl peptidase 40001
Endochitinase0101
5-hydroxytryptamine receptor 2B0404
Delta-type opioid receptor0304
Cytochrome P450 2C190606
Delta-type opioid receptor0416
Mu-type opioid receptor06110
Carbonic anhydrase 5A, mitochondrial08114
Carbonic anhydrase0809
Kappa-type opioid receptor0315
Carbonic anhydrase 707112
Carbonic anhydrase0101
D(1A) dopamine receptor3104
Corticosteroid 11-beta-dehydrogenase isozyme 10202
Carbonic anhydrase0102
D(2) dopamine receptor0506
Cholinesterase0101
Carbonic anhydrase 0101
Mu-type opioid receptor0505
Fatty-acid amide hydrolase 10101
Beta-carbonic anhydrase 10101
Carbonic anhydrase 20101
Glutamate receptor ionotropic, NMDA 2B0528
Squalene synthase0101
Neuronal acetylcholine receptor subunit alpha-70101
Carbonic anhydrase 9010217
Carbonic anhydrase0202
Carbonic anhydrase, alpha family 0303
Carbonic anhydrase 0102
Carbonic anhydrase 30101
Carbonic anhydrase0204
Carbonic anhydrase0103
Carbonic anhydrase 0202
Sigma intracellular receptor 20101
Delta carbonic anhydrase0202
Sigma non-opioid intracellular receptor 10314
Renin0101
Carbonic anhydrase 0102
Endochitinase A10101
Multidrug resistance-associated protein 10101
Carbonic anhydrase 130214
Canalicular multispecific organic anion transporter 1027027
Carbonic anhydrase 40202
Carbonic anhydrase 150507
Acidic mammalian chitinase0101
Carbonic anhydrase 1307011
Carbonic anhydrase 70101
Carbonic anhydrase 0303
Carbonic anhydrase 1406112
Carbonic anhydrase 0101
Carbonic anhydrase 2, isoform A 0101
Carbonic anhydrase 5B, mitochondrial08114
Luciferase9009
USP1 protein, partial200020
TDP1 protein320032
Microtubule-associated protein tau140014
AR protein390039
aldehyde dehydrogenase 1 family, member A1220022
estrogen nuclear receptor alpha470047
peroxisome proliferator activated receptor gamma210021
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a200020
vitamin D3 receptor isoform VDRA150015
thyroid hormone receptor beta isoform 2240024
flap endonuclease 16006
serine/threonine-protein kinase PLK14004
eyes absent homolog 2 isoform a3003
DNA polymerase eta isoform 13003
Bile salt export pump014014
Rap guanine nucleotide exchange factor 36006
Cellular tumor antigen p53270027
Rap guanine nucleotide exchange factor 42002
Chain A, Heat Shock Protein 900011
Chain A, GLUTAMINE PHOSPHORIBOSYLPYROPHOSPHATE AMIDOTRANSFERASE0011
Chain B, GLUTAMINE PHOSPHORIBOSYLPYROPHOSPHATE AMIDOTRANSFERASE0011
Chain A, EOSINOPHIL-DERIVED NEUROTOXIN0101
Chain A, EOSINOPHIL-DERIVED NEUROTOXIN0101
Chain A, EOSINOPHIL-DERIVED NEUROTOXIN0101
Chain A, Myosin Ie Heavy Chain0011
Chain A, Preprotein translocase secA0011
Chain A, Ribonuclease pancreatic0101
Chain A, Ribonuclease pancreatic0101
Chain A, Ribonuclease pancreatic0101
Chain A, Ribonuclease pancreatic0101
Chain A, Ribonuclease pancreatic0101
Chain A, Phosphoribosylformylglycinamidine synthase0101
Chain A, nucleoside diphosphate kinase A0011
Chain B, nucleoside diphosphate kinase A0011
Chain D, DNA polymerase III subunit gamma0011
Chain D, DNA polymerase III subunit gamma0011
Chain A [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 30011
Chain A [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 30011
Chain A, Kinesin-like protein KIF110101
regulator of G-protein signaling 4120012
HPr kinase/phosphorylase0011
Mitogen-activated protein kinase kinase kinase 70022
ATP-dependent molecular chaperone HSP820001
Heat shock protein HSP 90-alpha0113
Heat shock protein HSP 90-beta0113
2-dehydropantoate 2-reductase0246
Heat shock 70 kDa protein 1A 0112
Endoplasmic reticulum chaperone BiP0011
Heat shock cognate 71 kDa protein0011
Pyruvate kinase PKM 0001
Pyruvate kinase PKLR 0001
Endoplasmin0001
Heat shock cognate 71 kDa protein0011
5'-nucleotidase0101
Mu-type opioid receptor011315
Delta-type opioid receptor09313
Kappa-type opioid receptor011315
Endoplasmin0112
P2Y purinoceptor 20022
Phosphatidylinositol 4-kinase alpha0202
P2X purinoceptor 10011
P2Y purinoceptor 10022
P2Y purinoceptor 10022
P2X purinoceptor 10011
P2X purinoceptor 40011
P2X purinoceptor 50011
P2X purinoceptor 60011
P2X purinoceptor 30011
Inositol monophosphatase 15005
Heat shock protein 75 kDa, mitochondrial0101
P2Y purinoceptor 60022
Phosphatidylinositol 4-kinase type 2-beta0202
P2Y purinoceptor 110022
Phosphatidylinositol 4-kinase type 2-alpha0202
P2Y purinoceptor 120011
Sensor protein kinase WalK0101
Phosphatidylinositol 4-kinase beta0202
P2X purinoceptor 20011
Transient receptor potential cation channel subfamily M member 20112
Chain A, Glycogen Phosphorylase B0011
Chain B, Glycogen Phosphorylase B0011
Chain A, ADP-dependent glucokinase0101
Chain A, Ribonuclease pancreatic0101
Chain A, Ribonuclease pancreatic0101
Chain A, phosphodiesterase-nucleotide pyrophosphatase0101
Chain A, GLYCOGEN PHOSPHORYLASE B0011
Chain B, GLYCOGEN PHOSPHORYLASE B0011
Chain A, GLYCOGEN PHOSPHORYLASE B0011
RAR-related orphan receptor gamma270027
v-jun sarcoma virus 17 oncogene homolog (avian)190019
2'-deoxynucleoside 5'-phosphate N-hydrolase 10101
2'-deoxynucleoside 5'-phosphate N-hydrolase 10101
5'-AMP-activated protein kinase subunit beta-20012
Alcohol dehydrogenase E chain0101
Alcohol dehydrogenase S chain0101
L-lactate dehydrogenase A chain0112
Adenylate kinase isoenzyme 10001
Fructose-1,6-bisphosphatase 10101
Alkaline phosphatase, tissue-nonspecific isozyme0203
Fructose-1,6-bisphosphatase 10101
Inosine-5'-monophosphate dehydrogenase0101
Proto-oncogene tyrosine-protein kinase Src0101
Amine oxidase [flavin-containing] B0101
5'-nucleotidase0001
Choline O-acetyltransferase0101
Adenylate kinase 2, mitochondrial0102
GTP:AMP phosphotransferase AK3, mitochondrial0001
Adenylate kinase isoenzyme 1 0102
5'-AMP-activated protein kinase subunit gamma-10023
5'-AMP-activated protein kinase catalytic subunit alpha-20012
Adenylate kinase 2, mitochondrial0001
Glycine--tRNA ligase0101
5'-AMP-activated protein kinase catalytic subunit alpha-10023
Adenosine deaminase-like protein0001
Protease 0112
Histamine H3 receptor0101
5'-AMP-activated protein kinase subunit gamma-30012
5'-AMP-activated protein kinase subunit gamma-20012
5'-AMP-activated protein kinase subunit beta-10023
ATP-dependent phosphofructokinase150015
nuclear factor erythroid 2-related factor 2 isoform 26006
Sex hormone-binding globulin0145
Corticosteroid-binding globulin0404
Mineralocorticoid receptor 06411
Mineralocorticoid receptor0202
Solute carrier organic anion transporter family member 1A10203
Guanine nucleotide-binding protein G3003
Thromboxane-A synthase 0404
Prostaglandin E2 receptor EP3 subtype0101
Prostaglandin E2 receptor EP4 subtype0112
Prostaglandin E2 receptor EP1 subtype0101
Prostacyclin receptor0325
Nuclear receptor subfamily 4 group A member 20011
Solute carrier organic anion transporter family member 2A10103
Nuclear receptor subfamily 4 group A member 20011
Nuclear receptor subfamily 4 group A member 20011
Prostaglandin E2 receptor EP2 subtype0112
Solute carrier organic anion transporter family member 2A10001
Solute carrier organic anion transporter family member 2B10101
Solute carrier organic anion transporter family member 3A10001
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE180018
Chain U, UROKINASE-TYPE PLASMINOGEN ACTIVATOR0101
Chain A, UROKINASE-TYPE PLASMINOGEN ACTIVATOR0101
Chain A, UROKINASE-TYPE PLASMINOGEN ACTIVATOR0101
Chain A, HADH2 protein9009
Chain B, HADH2 protein9009
Chain A, 2-oxoglutarate Oxygenase7007
acid sphingomyelinase2002
acetylcholinesterase120012
glucocerebrosidase5005
alpha-galactosidase6006
cytochrome P450 2D6 isoform 15005
lysosomal alpha-glucosidase preproprotein4004
cytochrome P450 2C19 precursor5005
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 14004
huntingtin isoform 23003
lamin isoform A-delta10240024
Membrane primary amine oxidase 0101
Solute carrier family 22 member 1 010011
Prothrombin0112
Coagulation factor X0101
Plasminogen0101
Urokinase-type plasminogen activator0202
Tissue-type plasminogen activator0202
Cationic trypsin0101
Coagulation factor XI0101
Plasma kallikrein0203
Vitamin K-dependent protein C0101
Urokinase-type plasminogen activator0202
Trypsin-10101
Trypsin-20101
Sodium/hydrogen exchanger 10101
Amine oxidase [flavin-containing] A0101
Sodium/hydrogen exchanger 10202
Sodium/hydrogen exchanger 30202
Trypsin-30101
Amiloride-sensitive sodium channel subunit alpha0101
5-hydroxytryptamine receptor 70606
Sodium/hydrogen exchanger 20202
Acid-sensing ion channel 10101
Potassium voltage-gated channel subfamily H member 2012012
Sodium channel protein type 5 subunit alpha0606
Sodium/hydrogen exchanger 50202
Solute carrier family 22 member 10606
Solute carrier family 22 member 20606
Acid-sensing ion channel 30101
Sodium/hydrogen exchanger0101
DNA polymerase kappa isoform 17007
Atrial natriuretic peptide receptor 30101
Type-1A angiotensin II receptor 0213
Type-1 angiotensin II receptor0011
Type-1B angiotensin II receptor0202
Type-1 angiotensin II receptor0336
Type-2 angiotensin II receptor0202
Type-2 angiotensin II receptor0202
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN0011
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN0011
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN0011
phosphopantetheinyl transferase140014
NFKB1 protein, partial8008
GLS protein110011
chromobox protein homolog 1210021
DNA polymerase iota isoform a (long)6006
muscarinic acetylcholine receptor M1120012
lethal factor (plasmid)8008
Nitric oxide synthase, endothelial0002
Nitric oxide synthase, brain0001
Nitric oxide synthase, brain 0001
Nitric oxide synthase, inducible0001
Nitric oxide synthase, inducible0013
Cationic amino acid transporter 30101
Vasopressin V2 receptor0214
Oxytocin receptor0112
Vasopressin V1a receptor0033
Vasopressin V1a receptor0426
Vasopressin V1b receptor0112
Vasopressin V2 receptor0011
Vasopressin V1b receptor0113
Translocator protein0102
Oxytocin receptor0112
Vasopressin V2 receptor 0112
ATAD5 protein, partial6006
vasopressin V1b receptor1001
cAMP-dependent protein kinase type I-alpha regulatory subunit0011
cAMP-dependent protein kinase type II-beta regulatory subunit0011
urokinase-type plasminogen activator precursor3003
plasminogen precursor3003
cAMP-dependent protein kinase catalytic subunit beta isoform 10011
urokinase plasminogen activator surface receptor precursor3003
relaxin receptor 1 isoform 12002
relaxin receptor 2 isoform 12002
neuropeptide S receptor isoform A5005
cAMP-dependent protein kinase catalytic subunit beta isoform 30011
Chain A, Vitamin D Nuclear Receptor0011
Chain A, Ferritin light chain7007
Vitamin D3 receptor0011
PPM1D protein6006
thioredoxin glutathione reductase5005
nuclear receptor ROR-gamma isoform 1100010
Interferon beta200020
Vitamin D-binding protein0011
Androgen receptor08313
Vitamin D3 receptor0239
Vitamin D3 receptor0113
Retinoic acid receptor RXR-alpha0033
Vitamin D3 receptor0022
1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial0011
Vitamin D3 receptor0112
Transporter0101
Vitamin D3 receptor A0022
Chain A, Putative fructose-1,6-bisphosphate aldolase6006
Chain A, Cruzipain3003
SMAD family member 24004
SMAD family member 34004
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)9009
progesterone receptor210021
farnesoid X nuclear receptor180018
pregnane X nuclear receptor250025
G170017
bromodomain adjacent to zinc finger domain 2B6006
peroxisome proliferator-activated receptor delta140014
vitamin D (1,25- dihydroxyvitamin D3) receptor220022
activating transcription factor 6100010
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a110011
nuclear receptor subfamily 1, group I, member 24004
parathyroid hormone/parathyroid hormone-related peptide receptor precursor4004
transcriptional regulator ERG isoform 37007
importin subunit beta-1 isoform 13003
snurportin-13003
Voltage-dependent calcium channel gamma-2 subunit150015
HLA class I histocompatibility antigen, B alpha chain 170017
Glucocorticoid receptor013322
Glycine receptor subunit alpha-1012012
Glutamate receptor 2150015
Glycine receptor subunit beta012012
Glycine receptor subunit alpha-2012012
Glycine receptor subunit alpha-3012012
Spike glycoprotein101213
Inositol hexakisphosphate kinase 1170017
cytochrome P450 2C9, partial170017
EWS/FLI fusion protein110011
nonstructural protein 15005
ORF730011
Proteasome subunit beta type-110001
Fumarate hydratase6006
Thrombopoietin3003
Smad36006
caspase 7, apoptosis-related cysteine protease4004
estrogen receptor 2 (ER beta)160016
NADPH oxidase 10101
cytochrome P450 2D6150015
polyprotein6006
67.9K protein8008
Snq2p0001
caspase-34004
IDH1110011
Adenylate cyclase type 1 0202
Histone H2A.x120012
Caspase-73003
Spike glycoprotein0123
Replicase polyprotein 1ab0123
cellular tumor antigen p53 isoform a7007
D(1A) dopamine receptor6006
potassium voltage-gated channel subfamily H member 2 isoform d6006
caspase-33003
histone deacetylase 9 isoform 32002
heat shock protein beta-1110011
atrial natriuretic peptide receptor 2 precursor2002
ras-related protein Rab-9A3003
serine/threonine-protein kinase mTOR isoform 15005
M-phase phosphoprotein 87007
Proteasome subunit alpha type-70001
Polyunsaturated fatty acid lipoxygenase ALOX15B6006
Transmembrane protease serine 20123
Glutamate receptor ionotropic, NMDA 2D0101
Transient receptor potential cation channel subfamily V member 10101
Glutamate receptor ionotropic, NMDA 3B0101
Voltage-dependent L-type calcium channel subunit alpha-1F0505
5-hydroxytryptamine receptor 4012012
Potassium channel subfamily K member 20134
Epidermal growth factor receptor0303
Albumin07310
Albumin0033
Major prion protein0011
Sarcoplasmic/endoplasmic reticulum calcium ATPase 10202
Receptor tyrosine-protein kinase erbB-20202
Major prion protein0011
Integrin beta-35005
Tyrosine-protein kinase Fyn0404
Procathepsin L0123
Aldo-keto reductase family 1 member B1011011
Muscarinic acetylcholine receptor M20618
Muscarinic acetylcholine receptor M40405
ATP-dependent translocase ABCB1011113
Muscarinic acetylcholine receptor M10202
Muscarinic acetylcholine receptor M30202
Muscarinic acetylcholine receptor M40202
Integrin alpha-IIb5005
5-hydroxytryptamine receptor 1A0527
Muscarinic acetylcholine receptor M50202
Muscarinic acetylcholine receptor M50405
Alpha-2A adrenergic receptor011316
Replicase polyprotein 1a0123
Replicase polyprotein 1ab0123
Replicase polyprotein 1ab0224
Cys-loop ligand-gated ion channel0101
Calmodulin-10213
Replicase polyprotein 1ab0224
Muscarinic acetylcholine receptor M20202
Muscarinic acetylcholine receptor M10719
Polyunsaturated fatty acid lipoxygenase ALOX150707
Angiotensin-converting enzyme0404
D(2) dopamine receptor010112
Alpha-1B adrenergic receptor017118
Sphingomyelin phosphodiesterase0101
Alpha-2B adrenergic receptor0619
Alpha-2C adrenergic receptor0529
D0303
D(3) dopamine receptor0505
5-hydroxytryptamine receptor 1A010112
Alpha-2B adrenergic receptor0527
D(2) dopamine receptor0202
Muscarinic acetylcholine receptor M30719
Proteasome subunit beta type-10001
Substance-K receptor0606
D(1A) dopamine receptor08110
D(4) dopamine receptor0506
D(1B) dopamine receptor0102
Adenylate cyclase type 30202
Alpha-2C adrenergic receptor0527
UDP-glucuronosyltransferase 1A40103
Alpha-2A adrenergic receptor0527
Alpha-1D adrenergic receptor0718
Sodium-dependent noradrenaline transporter 010010
Sodium-dependent dopamine transporter0202
Histamine H2 receptor0606
Alpha-1D adrenergic receptor06210
D(1B) dopamine receptor0303
Proteasome subunit alpha type-10001
Proteasome subunit alpha type-20001
Proteasome subunit alpha type-30001
Proteasome subunit alpha type-40001
Adenylate cyclase type 20213
Adenylate cyclase type 40202
Proteasome subunit beta type-80001
Proteasome subunit beta type-90001
Proteasome subunit alpha type-50001
Proteasome subunit beta type-40001
Proteasome subunit beta type-60001
Proteasome subunit beta type-50001
5-hydroxytryptamine receptor 2A010111
5-hydroxytryptamine receptor 2C013114
5-hydroxytryptamine receptor 1B0909
Trypanothione reductase0202
D(4) dopamine receptor0303
Histamine H1 receptor0123
Sodium-dependent serotonin transporter012012
Melanocortin receptor 40404
5-hydroxytryptamine receptor 7 0101
Melanocortin receptor 50404
Pleiotropic ABC efflux transporter of multiple drugs0102
5-hydroxytryptamine receptor 70213
Histamine H1 receptor0202
Glutamate receptor ionotropic, NMDA 1 0427
D(3) dopamine receptor09010
Sodium channel protein type 1 subunit alpha0505
Sodium channel protein type 4 subunit alpha0405
Adenylate cyclase type 80202
Proteasome subunit beta type-100001
5-hydroxytryptamine receptor 2B012113
Melanocortin receptor 30404
Alpha-1A adrenergic receptor017118
Histamine H2 receptor82212
Proteasome subunit beta type-30001
Proteasome subunit beta type-20001
5-hydroxytryptamine receptor 6010111
Cytochrome P450 2J20808
Gastrin/cholecystokinin type B receptor0101
Proteasome subunit alpha type-60012
Calmodulin 0112
Aldehyde oxidase 10101
Glutamate receptor ionotropic, NMDA 2A 0427
Glutamate receptor ionotropic, NMDA 2C0427
Sodium channel protein type 7 subunit alpha0303
Voltage-dependent L-type calcium channel subunit alpha-1D 0505
Sodium-dependent dopamine transporter 010010
Adenylate cyclase type 60202
Adenylate cyclase type 50202
Glutamate receptor ionotropic, NMDA 10101
Aldehyde oxidase0505
Glutamate receptor ionotropic, NMDA 2A0101
Glutamate receptor ionotropic, NMDA 2B0101
Voltage-dependent L-type calcium channel subunit alpha-1S0505
Glutamate receptor ionotropic, NMDA 2C0101
Sodium channel protein type 9 subunit alpha0404
Glutamate receptor ionotropic, NMDA 2D0427
Nuclear receptor subfamily 3 group C member 3 0404
Adenylyl cyclase 7 0202
Proteasome subunit alpha-type 80001
Glutamate receptor ionotropic, NMDA 3A0101
Glutamate receptor ionotropic, NMDA 3B0427
D0101
Sodium channel protein type 2 subunit alpha0505
Proteasome subunit beta type-70001
Ataxin-28008
Sigma non-opioid intracellular receptor 10808
Angiotensin-converting enzyme 2 0224
Sodium channel protein type 3 subunit alpha0505
Glutamate receptor ionotropic, NMDA 3A0427
Sodium channel protein type 11 subunit alpha0303
Sodium channel protein type 8 subunit alpha0303
Histamine H3 receptor0101
Sodium channel protein type 10 subunit alpha0303
aryl hydrocarbon receptor110011
Lanosterol 14-alpha demethylase0303
cystic fibrosis transmembrane conductance regulator ATP-binding cassette sub-family C member 70001
interleukin 85005
15-lipoxygenase, partial5005
60 kDa chaperonin0202
60 kDa heat shock protein, mitochondrial0202
Glycine receptor subunit alpha-10033
Nuclear receptor ROR-gamma100010
10 kDa heat shock protein, mitochondrial0202
Thiosulfate sulfurtransferase0202
60 kDa chaperonin 0202
10 kDa chaperonin 0202
Solute carrier family 22 member 10101
Solute carrier family 22 member 20405
Solute carrier family 22 member 20101
ATP-dependent translocase ABCB10202
Potassium-transporting ATPase alpha chain 10101
ATP-dependent translocase ABCB10202
Potassium-transporting ATPase subunit beta0101
Solute carrier family 22 member 60405
Multidrug and toxin extrusion protein 20202
Solute carrier family 22 member 80608
Multidrug and toxin extrusion protein 10404
Histamine H4 receptor0101
Solute carrier family 22 member 110304
Solute carrier family 22 member 40101
Solute carrier family 22 member 80404
PINK11001
Parkin3003
Extracellular calcium-sensing receptor0011
pregnane X receptor8008
nuclear receptor subfamily 0 group B member 10101
steroidogenic factor 10101
histone-lysine N-methyltransferase 2A isoform 2 precursor4004
Nuclear receptor subfamily 1 group I member 20123
Solute carrier family 2, facilitated glucose transporter member 10011
Adenylate cyclase type 80011
Adenylate cyclase type 10113
ATPase family AAA domain-containing protein 56006
Relaxin receptor 10011
Nuclear receptor subfamily 1 group I member 20011
Solute carrier family 22 member 30101
Solute carrier family 22 member 30101
C-8 sterol isomerase0202
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase0314
Sodium- and chloride-dependent creatine transporter 10101
Proton-coupled amino acid transporter 10303
Multidrug resistance-associated protein 50001
hypoxia-inducible factor 1 alpha subunit100010
ubiquitin carboxyl-terminal hydrolase 2 isoform a2002
high affinity choline transporter 1 isoform a0101
DNA dC->dU-editing enzyme APOBEC-3G isoform 11001
Estrogen receptor010415
Beta-1 adrenergic receptor010313
Adenosine receptor A3012113
Acetylcholinesterase0303
Prostaglandin G/H synthase 10303
Alpha-synuclein2103
Estrogen-related receptor gamma0112
Disintegrin and metalloproteinase domain-containing protein 171102
TAR DNA-binding protein 433003
UDP-glucose 4-epimerase0101
Mitogen-activated protein kinase 140101
Estrogen receptor beta08412
Broad substrate specificity ATP-binding cassette transporter ABCG20404
Cysteinyl leukotriene receptor 10202
Chain A, Sex Hormone-Binding Globulin0011
thyrotropin-releasing hormone receptor3003
Progesterone receptor0101
Progesterone receptor0629
Glucocorticoid receptor0213
Sex hormone-binding globulin0101
Aromatase0102
Androgen receptor0112
Testosterone 17-beta-dehydrogenase 30101
Angiotensin-converting enzyme0112
Cannabinoid receptor 20112
G-protein coupled bile acid receptor 10112
Muscarinic acetylcholine receptor0101
Neuropeptide FF receptor 20001
ALK tyrosine kinase receptor0101
Voltage-dependent L-type calcium channel subunit alpha-1C0404
Voltage-dependent L-type calcium channel subunit alpha-1C0505
Voltage-dependent L-type calcium channel subunit alpha-1D0303
Voltage-dependent L-type calcium channel subunit alpha-1S0303
Potassium voltage-gated channel subfamily A member 10202
Eyes absent homolog 20202
Amyloid-beta precursor protein0101
Angiotensin-converting enzyme 0101
Metallo-beta-lactamase VIM-130101
Beta-lactamase 0101
Beta-lactamase 0101
Beta-lactamase VIM-1 0101
Vpr3003
Cytochrome P450 2B10101
Neuronal acetylcholine receptor subunit alpha-42002
Neuronal acetylcholine receptor subunit beta-22002
UDP-glucuronosyltransferase 1A1 0405
3-oxo-5-alpha-steroid 4-dehydrogenase 1 0202
Sulfotransferase 1A10214
Nuclear receptor subfamily 1 group I member 3 0101
apical membrane antigen 1, AMA15005
Type IV secretion-like conjugative transfer relaxase protein TraI 0101
Solute carrier family 15 member 10202
Glucose-6-phosphate 1-dehydrogenase0101
Corticosteroid 11-beta-dehydrogenase isozyme 10101
Adenosine receptor A10202
6-phosphogluconate dehydrogenase, decarboxylating0202
Holo-[acyl-carrier-protein] synthase0101
Sodium/bile acid cotransporter0202
G-protein coupled receptor 350112
CDGSH iron-sulfur domain-containing protein 10202
Beta-galactosidase0101
Lipopolysaccharide heptosyltransferase 10101
PA-I galactophilic lectin0011
Jacalin0011
Chain A, Glutamine Binding Protein0011
peripheral myelin protein 22 isoform 14004
Neutral amino acid transporter A0202
Asc-type amino acid transporter 10202
Neutral amino acid transporter B(0)0202
Carbonic anhydrase-like protein, putative0002
Amino acid transporter0202
Chain B, EUKARYOTIC TRANSLATION INITIATION FACTOR 4E0011
Sodium- and chloride-dependent GABA transporter 20101
Sodium- and chloride-dependent GABA transporter 30101
Sodium- and chloride-dependent glycine transporter 10101
Large neutral amino acids transporter small subunit 10303
Serine racemase0101
Olfactory receptor 51E20022
Sodium- and chloride-dependent glycine transporter 20101
Chain A, Probable hydrogenase nickel incorporation protein hypB0011
Chain B, Probable hydrogenase nickel incorporation protein hypB0011
Chain A, ELONGATION FACTOR TU (EF-TU)0011
Chain A, Elongation Factor G0011
Chain A, ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 30011
Chain A, Eukaryotic peptide chain release factor GTP-binding subunit0011
Chain A, ras-related C3 botulinum toxin substrate 1 isoform Rac1b0022
Chain A, ras-related C3 botulinum toxin substrate 1 isoform Rac1b0022
Chain A, interferon-inducible GTPase0011
Chain A, interferon-inducible GTPase0011
Chain A, Elongation factor 20011
Chain A, Guanine nucleotide-binding protein G(i), alpha-1 subunit0011
72 kDa type IV collagenase0202
Matrilysin0101
Ras-related protein Rab-7a0022
4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase FUT60101
4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase FUT50101
Alpha-(1,3)-fucosyltransferase 70101
CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 10101
4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase 90404
Chain A, Uracil Phosphoribosyltransferase0011
Chain B, Uracil Phosphoribosyltransferase0011
Chain C, Uracil Phosphoribosyltransferase0011
Protein-glutamine gamma-glutamyltransferase 20101
Hsf1 protein0011
cytochrome P450 2C9 precursor3003
Prostaglandin E2 receptor EP1 subtype0011
Prostaglandin E2 receptor EP3 subtype0101
Prostaglandin E2 receptor EP2 subtype0011
Prostacyclin receptor0112
Prostaglandin D2 receptor0011
NPYLR7B0011
Beta-1 adrenergic receptor 0125
beta-2 adrenergic receptor3003
hexokinase-4 isoform 12002
glucokinase regulatory protein2002
Beta-2 adrenergic receptor06411
Beta-2 adrenergic receptor0417
Beta-3 adrenergic receptor07310
Beta-1 adrenergic receptor0429
Beta-2 adrenergic receptor0011
Beta-adrenergic receptor kinase 10011
Beta-3 adrenergic receptor0011
Beta-3 adrenergic receptor0314
Beta-1 adrenergic receptor0213
Alpha-1A adrenergic receptor0136
Alpha-1B adrenergic receptor0024
Beta-2 adrenergic receptor0202
Taste receptor type 2 member 380011
Taste receptor type 2 member 390011
Taste receptor type 2 member 400011
Taste receptor type 2 member 410011
Taste receptor type 2 member 430011
Taste receptor type 2 member 310011
Taste receptor type 2 member 450011
Taste receptor type 2 member 460011
Taste receptor type 2 member 300011
Taste receptor type 2 member 190011
Taste receptor type 2 member 200011
Taste receptor type 2 member 500011
Taste receptor type 2 member 600011
Beta-2 adrenergic receptor 0112
Taste receptor type 2 member 420011
Beta-2 adrenergic receptor0237
Taste receptor type 2 member 160011
Taste receptor type 2 member 140011
Taste receptor type 2 member 130011
Taste receptor type 2 member 100011
Taste receptor type 2 member 90011
Taste receptor type 2 member 80011
Taste receptor type 2 member 70011
Taste receptor type 2 member 50011
Taste receptor type 2 member 40011
Taste receptor type 2 member 30011
Taste receptor type 2 member 10011
2,3-bisphosphoglycerate-independent phosphoglycerate mutase1001
Chain A, ATP-DEPENDENT DNA HELICASE Q11001
dopamine D1 receptor1001
WRN1001
integrase, partial0101
lens epithelium-derived growth factor p750101
pyruvate kinase1001
atrial natriuretic peptide receptor 1 precursor2002
peptidyl-prolyl cis-trans isomerase NIMA-interacting 13003
Polyphenol oxidase 20306
Tyrosine-protein kinase Lck0202
Tyrosinase0101
SLC16A10 protein0001
Monocarboxylate transporter 100001
phosphoglycerate kinase1001
Dopamine beta-hydroxylase 0202
Lactoperoxidase0101
Chain A, Methionyl-tRNA synthetase0011
Chain A, Methionyl-tRNA synthetase0011
Chain A, Aminopeptidase0101
Chain A, Methionine aminopeptidase0101
S-ribosylhomocysteine lyase0101
Adenylate cyclase type 50001
S-adenosylmethionine synthase isoform type-10001
S-adenosylmethionine synthase isoform type-20001
Fatty acid synthase0101
5-hydroxytryptamine receptor 3E0011
5-hydroxytryptamine receptor 3B0011
Myeloperoxidase0101
5-hydroxytryptamine receptor 3A0101
5-hydroxytryptamine receptor 1D0202
5-hydroxytryptamine receptor 1F0202
5-hydroxytryptamine receptor 3A0202
5-hydroxytryptamine receptor 3A0011
Lactoperoxidase0101
5-hydroxytryptamine receptor 4 0102
5-hydroxytryptamine receptor 3D0011
5-hydroxytryptamine receptor 3C0011
5-hydroxytryptamine receptor 3B0101
5-hydroxytryptamine receptor 3B0202
serine-protein kinase ATM isoform a1001
nuclear factor NF-kappa-B p105 subunit isoform 11001
lethal(3)malignant brain tumor-like protein 1 isoform I1001
Peroxisome proliferator-activated receptor alpha1001
Opioid receptor, delta 1b 0101
Acetylcholinesterase0101
Opioid receptor homologue0101
Acyl-CoA desaturase 10101
Histidine decarboxylase0011
Proteinase-activated receptor 10112
Kappa-type opioid receptor0214
Kappa-type opioid receptor0214
UDP-glucuronosyltransferase 1A30001
Mu-type opioid receptor0215
Nociceptin receptor0101
Mu-type opioid receptor0101
Mas-related G-protein coupled receptor member X20011
Mu-type opioid receptor0101
Chain B, Exotoxin A0011
Chain B, Exotoxin A0011
Chain B, Exotoxin A0011
Atrial natriuretic peptide receptor 10101
hypothetical protein, conserved1001
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)2002
tumor necrosis factor1001
polyunsaturated fatty acid lipoxygenase ALOX122002
perilipin-50101
perilipin-10101
1-acylglycerol-3-phosphate O-acyltransferase ABHD5 isoform a0101
Glutathione reductase, mitochondrial0202
Phospholipase A2, membrane associated0001
Potassium voltage-gated channel subfamily A member 50101
Platelet-activating factor receptor0001
Indoleamine 2,3-dioxygenase 10101
3-oxo-5-alpha-steroid 4-dehydrogenase 20101
C-C chemokine receptor type 20202
Voltage-dependent L-type calcium channel subunit alpha-1C0101
Voltage-dependent L-type calcium channel subunit alpha-1S0101
C-terminal-binding protein 11001
Leukotriene B4 receptor 10001
Myosin light chain kinase, smooth muscle0101
Transient receptor potential cation channel subfamily A member 10011
Potassium channel subfamily K member 2 0101
Indoleamine 2,3-dioxygenase 20101
Voltage-dependent L-type calcium channel subunit alpha-1D0101
Voltage-dependent L-type calcium channel subunit alpha-1F0101
Leukotriene B4 receptor 20001
Solute carrier family 2, facilitated glucose transporter member 90224
Cystathionine gamma-lyase0202
Succinyl-diaminopimelate desuccinylase0101
Cholecystokinin receptor type A0101
Gastrin/cholecystokinin type B receptor0011
Gastrin/cholecystokinin type B receptor0112
mu-type opioid receptor isoform MOR-10011
5-hydroxytryptamine receptor 2A0011
Gamma-aminobutyric acid 0101
endonuclease IV3003
Gamma-aminobutyric acid receptor subunit pi0202
Gamma-aminobutyric acid receptor subunit delta0202
Dihydrofolate reductase 0101
Sodium channel protein type 2 subunit alpha0101
Gamma-aminobutyric acid receptor subunit alpha-10202
Aldo-keto reductase family 1 member B10101
Gamma-aminobutyric acid receptor subunit alpha-60101
Gamma-aminobutyric acid receptor subunit beta-10202
Gamma-aminobutyric acid receptor subunit gamma-20202
Gamma-aminobutyric acid receptor subunit gamma-20101
Gamma-aminobutyric acid receptor subunit delta0101
Gamma-aminobutyric acid receptor subunit alpha-20101
Gamma-aminobutyric acid receptor subunit alpha-30101
Gamma-aminobutyric acid receptor subunit gamma-30101
Gamma-aminobutyric acid receptor subunit beta-30202
Gamma-aminobutyric acid receptor subunit alpha-50202
Gamma-aminobutyric acid receptor subunit alpha-30202
Gamma-aminobutyric acid receptor subunit alpha-20202
Gamma-aminobutyric acid receptor subunit beta-20202
Gamma-aminobutyric acid receptor subunit alpha-40202
Gamma-aminobutyric acid receptor subunit beta-10101
Gamma-aminobutyric acid receptor subunit alpha-10101
Gamma-aminobutyric acid receptor subunit beta-30101
Gamma-aminobutyric acid receptor subunit epsilon0202
Gamma-aminobutyric acid receptor subunit alpha-60202
Gamma-aminobutyric acid receptor subunit alpha-50101
Gamma-aminobutyric acid receptor subunit gamma-10202
Gamma-aminobutyric acid receptor subunit pi0101
Gamma-aminobutyric acid receptor subunit gamma-30202
Gamma-aminobutyric acid receptor subunit alpha-40101
Gamma-aminobutyric acid receptor subunit theta0101
Gamma-aminobutyric acid receptor subunit gamma-10101
Gamma-aminobutyric acid receptor subunit theta0202
5-hydroxytryptamine receptor 1B0314
luciferase0001
Fatty acid-binding protein, liver0101
Glucocorticoid receptor0011
Glutamine synthetase0011
Prostaglandin G/H synthase 20202
Nociceptin receptor0011
Solute carrier organic anion transporter family member 1A40204
UDP-glucuronosyltransferase 1A90102
Transient receptor potential cation channel subfamily A member 10011
Solute carrier family 22 member 80101
UDP-glucuronosyltransferase 1-60203
Solute carrier family 22 member 70102
Canalicular multispecific organic anion transporter 10101
Solute carrier family 22 member 200202
Solute carrier family 22 member 60202
Pannexin-10101
Solute carrier family 22 member 120101
Solute carrier organic anion transporter family member 1C10202
UDP-glucuronosyltransferase 1A70101
UDP-glucuronosyltransferase 1A100101
Pannexin-10101
Solute carrier family 22 member 70203
Endothelin-1 receptor0112
Neuromedin-K receptor0011
Cholecystokinin receptor type A0112
Nuclear receptor subfamily 2 group E member 10022
Chain A, dATP pyrophosphohydrolase0101
Chain A, Adenylate cyclase type 50101
Chain B, Adenylate cyclase type 20101
chaperonin-containing TCP-1 beta subunit homolog1001
Estrogen receptor beta0001
Inhibitor of nuclear factor kappa-B kinase subunit beta0001
Polymerase acidic protein0011
Stromelysin-10112
Tyrosine-protein phosphatase YopH0101
High mobility group protein B10011
Aldo-keto reductase family 1 member B10101
Prolyl 4-hydroxylase subunit alpha-10101
Tyrosine-protein phosphatase non-receptor type 10103
Estrogen receptor0001
Xanthine dehydrogenase/oxidase0101
Nicotinate phosphoribosyltransferase0101
Ubiquitin-like domain-containing CTD phosphatase 10101
Chain A, Mineralocorticoid receptor0101
Chain A, Mineralocorticoid receptor0101
Orexin receptor type 10001
Cathepsin B0101
Fatty acid-binding protein, liver0101
Cannabinoid receptor 10228
Multidrug resistance-associated protein 1 0101
Cannabinoid receptor 2 0216
Cannabinoid receptor 10314
C-X-C chemokine receptor type 30101
N-arachidonyl glycine receptor0101
G-protein coupled receptor 550011
Chain A, MALTOPORIN0011
Chain B, MALTOPORIN0011
Chain A, CES1 protein0101
DNA polymerase III, partial1001
NPC intracellular cholesterol transporter 1 precursor1001
interferon gamma precursor0001
ubiquitin-conjugating enzyme E2 N0101
streptokinase A precursor0011
Serine/threonine-protein kinase D30101
Lysosomal acid glucosylceramidase0011
Protein kinase C gamma type0101
Protein kinase C alpha type0101
Protein kinase C beta type0101
Estrogen receptor0012
Protein kinase C delta type0101
Protein kinase C epsilon type0101
Protein kinase C zeta type0101
Steroid hormone receptor ERR10101
Transcriptional activator protein LuxR0101
Protein kinase C alpha type0101
Protein kinase C eta type0101
Substance-P receptor0202
B2 bradykinin receptor0202
Protein kinase C iota type0101
Protein kinase C gamma type0101
Protein kinase C beta type0101
Phospholipase D1 0101
Protein kinase C epsilon type0101
Protein kinase C theta type0101
Protein kinase C zeta type0101
Protein kinase C delta type0101
Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform0101
Platelet-activating factor acetylhydrolase0101
Phospholipase D10101
Serine/threonine-protein kinase D10101
Estrogen receptor beta0012
Protein kinase C eta type0101
Emopamil-binding protein-like0101
7-dehydrocholesterol reductase0112
Protein kinase C theta type0101
90-kda heat shock protein beta HSP90 beta, partial0101
estrogen receptor beta isoform 10101
heat shock protein HSP 90-alpha isoform 20101
tyrosine-protein phosphatase non-receptor type 7 isoform 20101
Dihydroxyacetone phosphate acyltransferase0001
30S ribosomal protein S60101
30S ribosomal protein S70101
50S ribosomal protein L150101
Tetracycline resistance protein, class B0001
50S ribosomal protein L100101
50S ribosomal protein L110101
50S ribosomal protein L7/L120101
50S ribosomal protein L190101
50S ribosomal protein L10101
50S ribosomal protein L200101
50S ribosomal protein L270101
50S ribosomal protein L280101
50S ribosomal protein L290101
50S ribosomal protein L310101
50S ribosomal protein L31 type B0101
50S ribosomal protein L320101
50S ribosomal protein L330101
50S ribosomal protein L340101
50S ribosomal protein L350101
50S ribosomal protein L360101
30S ribosomal protein S100101
30S ribosomal protein S110101
30S ribosomal protein S120101
30S ribosomal protein S130101
30S ribosomal protein S160101
30S ribosomal protein S180101
30S ribosomal protein S190101
30S ribosomal protein S200101
30S ribosomal protein S20101
30S ribosomal protein S30101
30S ribosomal protein S40101
30S ribosomal protein S50101
30S ribosomal protein S80101
30S ribosomal protein S90101
50S ribosomal protein L130101
50S ribosomal protein L140101
50S ribosomal protein L160101
50S ribosomal protein L230101
30S ribosomal protein S150101
Multidrug transporter MdfA0101
50S ribosomal protein L170101
50S ribosomal protein L210101
50S ribosomal protein L300101
50S ribosomal protein L60101
30S ribosomal protein S140101
30S ribosomal protein S170101
30S ribosomal protein S10101
50S ribosomal protein L180101
Neutrophil collagenase0101
Collagenase 30101
50S ribosomal protein L20101
50S ribosomal protein L30101
50S ribosomal protein L240101
50S ribosomal protein L40101
50S ribosomal protein L220101
50S ribosomal protein L50101
30S ribosomal protein S210101
50S ribosomal protein L250101
50S ribosomal protein L36 20101
Integrase 0101
P2Y purinoceptor 120101
Protein-arginine deiminase type-40101
Cereblon isoform 40202
Prostaglandin G/H synthase 10101
cAMP-specific 3',5'-cyclic phosphodiesterase 4A0303
Prostaglandin G/H synthase 20101
cAMP-specific 3',5'-cyclic phosphodiesterase 4C0303
DNA-binding protein Ikaros0001
DNA damage-binding protein 10112
Protein cereblon0214
Chain A, Pyridoxal kinase0101
Chain A, Pyridoxal Kinase0101
Intestinal-type alkaline phosphatase0101
Thyroid hormone receptor beta0202
Adenosine receptor A10202
Vasopressin V2 receptor0001
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform 0101
Adenosine receptor A10101
Chitotriosidase-10101
Adenosine receptor A2b0001
Palmitoleoyl-protein carboxylesterase NOTUM0011
Endochitinase B10101
Phospholipase A-2-activating protein0101
Chain X, Thyroid hormone receptor beta-10022
Chain X, Thyroid hormone receptor beta-10022
Solute carrier organic anion transporter family member 1A50002
Transthyretin0103
Thyroid hormone receptor alpha0235
Thyroid hormone receptor beta0235
Proliferating cell nuclear antigen0202
Peroxisome proliferator-activated receptor gamma0044
Malate dehydrogenase, mitochondrial0101
Solute carrier organic anion transporter family member 1A20002
Solute carrier organic anion transporter family member 1A30002
Solute carrier organic anion transporter family member 4C10102
Monocarboxylate transporter 80001
Bile acid receptor0101
Solute carrier organic anion transporter family member 1C10001
Solute carrier organic anion transporter family member 1B10002
chaperonin GroEL1001
UDP-glucuronosyltransferase 2B70203
UDP-glucuronosyltransferase 2B10 0101
Solute carrier organic anion transporter family member 4C10001
Solute carrier organic anion transporter family member 4A10001
Solute carrier organic anion transporter family member 1B30001
Urease subunit alpha0101
Urease subunit beta0101
Chain A, Glycogen phosphorylase, liver form0011
Chain A, glycogen phosphorylase, liver form0011
Chain A, Glycogen phosphorylase, liver form0011
Chain A, Glycogen phosphorylase, liver form0011
Guanine deaminase0101
Cocaine esterase0101
Histone deacetylase 30202
Tissue factor0101
Aldo-keto reductase family 1 member A10101
Liver carboxylesterase 10101
Aldo-keto reductase family 1 member A10101
Histone deacetylase 40202
Histone deacetylase 10202
Aldo-keto reductase family 1 member A10101
Aldo-keto reductase family 1 member B70101
Histone deacetylase 70202
Histone deacetylase 20202
Polyamine deacetylase HDAC100202
Histone deacetylase 11 0202
Histone deacetylase 80202
NAD-dependent protein deacylase sirtuin-5, mitochondrial0101
Histone deacetylase 60202
Histone deacetylase 90202
Histone deacetylase 50202
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]