Page last updated: 2024-11-06

thyroxine and Pseudohypoparathyroidism

thyroxine has been researched along with Pseudohypoparathyroidism in 17 studies

Thyroxine: The major hormone derived from the thyroid gland. Thyroxine is synthesized via the iodination of tyrosines (MONOIODOTYROSINE) and the coupling of iodotyrosines (DIIODOTYROSINE) in the THYROGLOBULIN. Thyroxine is released from thyroglobulin by proteolysis and secreted into the blood. Thyroxine is peripherally deiodinated to form TRIIODOTHYRONINE which exerts a broad spectrum of stimulatory effects on cell metabolism.
thyroxine : An iodothyronine compound having iodo substituents at the 3-, 3'-, 5- and 5'-positions.

Pseudohypoparathyroidism: A hereditary syndrome clinically similar to HYPOPARATHYROIDISM. It is characterized by HYPOCALCEMIA; HYPERPHOSPHATEMIA; and associated skeletal development impairment and caused by failure of response to PARATHYROID HORMONE rather than deficiencies. A severe form with resistance to multiple hormones is referred to as Type 1a and is associated with maternal mutant allele of the ALPHA CHAIN OF STIMULATORY G PROTEIN.

Research Excerpts

ExcerptRelevanceReference
"Hypothyroidism is a manifestation of multi-hormonal resistance in pseudohypoparathyroidism type Ia (PHP Ia)."1.35Hypothyroidism in patients with pseudohypoparathyroidism type Ia: clinical evidence of resistance to TSH and TRH. ( Balavoine, AS; Cardot-Bauters, C; d'Herbomez, M; Ladsous, M; Velayoudom, FL; Vlaeminck, V; Wemeau, JL, 2008)
"Pseudohypoparathyroidism Ia (PHP Ia) is characterized by resistance to PTH and many other stimuli because of deficiency of stimulatory G protein alpha-subunit."1.31Pseudohypoparathyroidism Ia and hypercalcitoninemia. ( Bauters, C; D'herbomez, M; Decoulx, M; Fayard, A; Pigny, P; Vlaeminck-Guillem, V; Wémeau, JL, 2001)
"Pseudohypoparathyroidism is an inherited disorder associated with resistance to the action of several hormones, including parathyroid hormone, thyroid-stimulating hormone, follicle-stimulating hormone, and luteinizing hormone."1.26Deficiency of hormone receptor-adenylate cyclase coupling protein: basis for hormone resistance in pseudohypoparathyroidism. ( Aurbach, GD; Breslau, NA; Downs, RW; Lasker, RD; Levine, MA; Marx, SJ; Moses, AM; Spiegel, AM, 1982)
"Moderate hypothyroidism is frequently present in pseudohypoparathyroidism."1.26[Pseudohypoparathyroidism with hypothyroidism (author's transl)]. ( Stögmann, W, 1981)

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19909 (52.94)18.7374
1990's1 (5.88)18.2507
2000's4 (23.53)29.6817
2010's3 (17.65)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ochiai, D1
Uchino, H1
Ikeda, T1
Yakubo, K1
Fukuiya, T1
Salerno, M1
Capalbo, D1
Cerbone, M1
De Luca, F1
Guedes Ramallo, P1
Boix Carreño, E1
Balavoine, AS1
Ladsous, M1
Velayoudom, FL1
Vlaeminck, V1
Cardot-Bauters, C1
d'Herbomez, M2
Wemeau, JL2
Nwosu, BU1
Lee, MM1
Gerhardt, A1
Hackenberg, K1
Spiegel, AM1
Levine, MA1
Aurbach, GD1
Downs, RW1
Marx, SJ1
Lasker, RD1
Moses, AM1
Breslau, NA1
Stögmann, W1
Vlaeminck-Guillem, V1
Pigny, P1
Fayard, A1
Bauters, C1
Decoulx, M1
Carlson, HE1
Brickman, AS1
Werder, EA1
Kind, HP1
Egert, F1
Fischer, JA1
Prader, A1
Yokoro, S1
Matsuo, M1
Ohtsuka, T1
Ohzeki, T1
Barajas de Frutos, D1
Pedrero Vera, J1
Bolívar Barrales, JE1
Espigares Martín, R1
Ortega Martos, L1
Vílchez Joya, R1
Bolívar Galiano, V1
Morell Bernabé, JJ1
Illán Gómez, F1
Madrid Conesa, J1
Pascual Saura, H1
Ramírez Muñoz, LM1
Cuenca Sánchez, JR1
Tébar Massó, FJ1
Mulaisho, C1
al-Hamdan, AR1
Suh, SM1
Kooh, SW1
Chan, AM1
Fraser, D1
Tashjian, AH1
Cederbaum, SD1
Lippe, BM1

Reviews

1 review available for thyroxine and Pseudohypoparathyroidism

ArticleYear
Subclinical hypothyroidism in childhood - current knowledge and open issues.
    Nature reviews. Endocrinology, 2016, Volume: 12, Issue:12

    Topics: Anticonvulsants; Antiviral Agents; Asymptomatic Diseases; Atherosclerosis; Bone Diseases, Metabolic;

2016

Other Studies

16 other studies available for thyroxine and Pseudohypoparathyroidism

ArticleYear
Pseudohypoparathyroidism type 1a in pregnancy.
    Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology, 2013, Volume: 33, Issue:8

    Topics: Adult; Calcitriol; Calcium Carbonate; Female; Humans; Pregnancy; Pregnancy Complications; Pseudohypo

2013
Management of pseudohypoparathyroidism in pregnancy: a case report.
    Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology, 2017, Volume: 37, Issue:4

    Topics: Adult; Breech Presentation; Calcium; Cesarean Section; Chromogranins; DNA Methylation; Female; GTP-B

2017
Hypothyroidism in patients with pseudohypoparathyroidism type Ia: clinical evidence of resistance to TSH and TRH.
    European journal of endocrinology, 2008, Volume: 159, Issue:4

    Topics: Adult; Chromogranins; Erythrocytes; Female; GTP-Binding Protein alpha Subunits, Gs; Humans; Hypothyr

2008
Pseudohypoparathyroidism type 1a and insulin resistance in a child.
    Nature reviews. Endocrinology, 2009, Volume: 5, Issue:6

    Topics: Child, Preschool; Female; Growth Hormone; Humans; Insulin Resistance; Pseudohypoparathyroidism; Thyr

2009
Pseudohypoparathyroidism and Graves'disease: a rare combination of two endocrinological diseases.
    Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association, 2002, Volume: 110, Issue:5

    Topics: Adult; Calcitriol; Calcium; Calcium Carbonate; Female; Graves Disease; Humans; Methimazole; Parathyr

2002
Deficiency of hormone receptor-adenylate cyclase coupling protein: basis for hormone resistance in pseudohypoparathyroidism.
    The American journal of physiology, 1982, Volume: 243, Issue:1

    Topics: Adenylyl Cyclases; Animals; Cyclic AMP; Erythrocyte Membrane; Guanosine Triphosphate; Humans; Macrom

1982
[Pseudohypoparathyroidism with hypothyroidism (author's transl)].
    Padiatrie und Padologie, 1981, Volume: 16, Issue:4

    Topics: Adolescent; Calcium; Child; Female; Follicle Stimulating Hormone; Humans; Hypothyroidism; Luteinizin

1981
Pseudohypoparathyroidism Ia and hypercalcitoninemia.
    The Journal of clinical endocrinology and metabolism, 2001, Volume: 86, Issue:7

    Topics: Adult; Calcitonin; Carcinoma, Medullary; Cyclic AMP; Drosophila Proteins; Female; GTP-Binding Protei

2001
Effect of hypocalcemia on hormonal responses to thyrotropin-releasing hormone.
    The Journal of clinical endocrinology and metabolism, 1977, Volume: 45, Issue:2

    Topics: Adolescent; Adult; Child; Female; Humans; Hypocalcemia; Hypoparathyroidism; Hypothyroidism; Kinetics

1977
Effective long-term treatment of pseudohypoparathyroidism with oral 1alpha-hydroxy- and 1,25-dihydroxy-cholecalciferol.
    The Journal of pediatrics, 1976, Volume: 89, Issue:2

    Topics: Administration, Oral; Adult; Alkaline Phosphatase; Calcium; Child; Child, Preschool; Dihydroxycholec

1976
Hyperthyrotropinemia in a neonate with normal thyroid hormone levels: the earliest diagnostic clue for pseudohypoparathyroidism.
    Biology of the neonate, 1990, Volume: 58, Issue:2

    Topics: Calcium; Creatinine; Cyclic AMP; Humans; Hydroxycholecalciferols; Hyperthyroidism; Infant; Phosphoru

1990
[Parathyroid insufficiency syndrome. Two new cases: type Ia pseudohypoparathyroidism and pseudo-idiopathic hypoparathyroidism].
    Anales espanoles de pediatria, 1989, Volume: 31, Issue:4

    Topics: Calcitriol; Calcium; Child; Cyclic AMP; Female; Humans; Hypocalcemia; Hypoparathyroidism; Male; Para

1989
[Pseudohypoparathyroidism: clinical variants (apropos of 3 new cases)].
    Medicina clinica, 1987, Oct-17, Volume: 89, Issue:12

    Topics: Adult; Calcium; Child; Cyclic AMP; Humans; Male; Pseudohypoparathyroidism; Tetany; Thyroxine; Vitami

1987
Pituitary resistance to L-thyroxine after thyroidectomy. A case report.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1989, Mar-04, Volume: 75, Issue:5

    Topics: Adult; Drug Resistance; Female; Humans; Pituitary Gland; Postoperative Complications; Pseudohypopara

1989
Pseudohypoparathyroidism: no improvement following total thyroidectomy.
    The Journal of clinical endocrinology and metabolism, 1969, Volume: 29, Issue:4

    Topics: Calcitonin; Calcium; Child; Cholesterol; Female; Humans; Hypocalcemia; Iodine Radioisotopes; Parathy

1969
Probable autosomal recessive inheritance in a family with Albright's hereditary osteodystrophy and an evaluation of the genetics of the disorder.
    American journal of human genetics, 1973, Volume: 25, Issue:6

    Topics: Alkaline Phosphatase; Autoradiography; Calcium; Child; Cyclic AMP; Female; Genes, Dominant; Genes, R

1973