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alanine and Lathyrism

alanine has been researched along with Lathyrism in 13 studies

Alanine: A non-essential amino acid that occurs in high levels in its free state in plasma. It is produced from pyruvate by transamination. It is involved in sugar and acid metabolism, increases IMMUNITY, and provides energy for muscle tissue, BRAIN, and the CENTRAL NERVOUS SYSTEM.
alanine : An alpha-amino acid that consists of propionic acid bearing an amino substituent at position 2.

Lathyrism: A paralytic condition of the legs caused by ingestion of lathyrogens, especially BETA-AMINOPROPIONITRILE or beta-N-oxalyl amino-L-alanine, which are found in the seeds of plants of the genus LATHYRUS.

Research Excerpts

ExcerptRelevanceReference
"beta-N-Oxalylamino-L-alanine (BOAA) and beta-N-methylamino-L-alanine (BMAA) are chemically related excitant amino acids isolated from the seed of Lathyrus sativus (BOAA) and Cycas circinalis (BMAA), consumption of which has been linked to lathyrism (an upper motor neuron disorder) and Guam amyotrophic lateral sclerosis (ALS), respectively."3.67Discovery and partial characterization of primate motor-system toxins. ( Hugon, J; Ludolph, A; Nunn, PB; Ross, SM; Roy, DN; Schaumburg, HH; Spencer, PS, 1987)

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-199010 (76.92)18.7374
1990's1 (7.69)18.2507
2000's1 (7.69)29.6817
2010's1 (7.69)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Haque, RM1
Kuo, YH1
Lambein, F2
Hussain, M1
RESSLER, C2
NELSON, J1
PFEFFER, M1
Brennan, L1
Alves, PM1
Hewage, C1
Malthouse, JP1
McBean, GJ1
Malathi, K1
Padmanaban, G1
Rao, SL1
Sarma, PS1
Riepe, M1
Spencer, PS4
Ludolph, AC1
Allen, CN1
Roy, DN3
Ludolph, A2
Hugon, J2
Dwivedi, MP1
Schaumburg, HH2
Nunn, PB2
Ross, SM2
Seelig, M1
Miller, EJ1
Tschiersch, B1
Aleo, JJ1
Cammarata, A1
Bensusan, HB1
McKnight, SD1
Naidu, MS1

Reviews

1 review available for alanine and Lathyrism

ArticleYear
[Toxic amino acids. A report].
    Die Pharmazie, 1966, Volume: 21, Issue:8

    Topics: Alanine; Amino Acids; Animals; Bacillus; Canavanine; Cycloserine; Fungi; Lathyrism; Plants; Rats

1966

Other Studies

12 other studies available for alanine and Lathyrism

ArticleYear
Effect of environmental factors on the biosynthesis of the neuro-excitatory amino acid β-ODAP (β-N-oxalyl-L-α,β-diaminopropionic acid) in callus tissue of Lathyrus sativus.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2011, Volume: 49, Issue:3

    Topics: Alanine; Amino Acids, Diamino; Excitatory Amino Acids; Isoxazoles; Lathyrism; Lathyrus; Micronutrien

2011
A PYRIDOXAL-BETA-CYANOALANINE RELATION IN THE RAT.
    Nature, 1964, Sep-19, Volume: 203

    Topics: Alanine; Amino Acids; Anticonvulsants; Chromatography; Cysteine; Enzyme Inhibitors; Lathyrism; Pepti

1964
Isolation and identification from common vetch of the neurotoxin beta-cyano-L-alanine, a possible factor in neurolathyrism.
    The Journal of biological chemistry, 1962, Volume: 237

    Topics: Alanine; Cyanides; Herbicides; Lathyrism; Nervous System; Neurotoxins; Plants; Vicia sativa

1962
Impact of the gliotoxin L-serine-O-sulphate on cellular metabolism in cultured rat astrocytes.
    Neurochemistry international, 2006, Volume: 48, Issue:8

    Topics: Alanine; Alanine Transaminase; Animals; Animals, Newborn; Aspartate Aminotransferases; Astrocytes; C

2006
Studies on the biosynthesis of beta-N-oxalyl-L-alpha, beta-diaminopropionic acid, the Lathyrus sativus neurotoxin.
    Biochimica et biophysica acta, 1967, Jun-13, Volume: 141, Issue:1

    Topics: Adenosine Triphosphate; Alanine; Amino Acids; Carbon Isotopes; Chromatography, Paper; Coenzyme A; El

1967
In vitro toxicological investigations of isoxazolinone amino acids of Lathyrus sativus.
    Natural toxins, 1995, Volume: 3, Issue:1

    Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Alanine; Aminobutyrates; Animals; Electrophysiology; Hippocamp

1995
Lathyrism: evidence for role of the neuroexcitatory aminoacid BOAA.
    Lancet (London, England), 1986, Nov-08, Volume: 2, Issue:8515

    Topics: Adolescent; Adult; Alanine; Amino Acids, Diamino; Animals; beta-Alanine; Central Nervous System; Chi

1986
Discovery and partial characterization of primate motor-system toxins.
    Ciba Foundation symposium, 1987, Volume: 126

    Topics: Alanine; Amino Acids, Diamino; Animals; beta-Alanine; Cyanobacteria Toxins; Humans; Lathyrism; Macac

1987
Detection and characterization of plant-derived amino acid motorsystem toxins in mouse CNS cultures.
    Progress in clinical and biological research, 1987, Volume: 253

    Topics: Alanine; Amino Acids, Diamino; Animals; beta-Alanine; Cell Survival; Cells, Cultured; Central Nervou

1987
Isolation and characterization of a collagen from chick cartilage containing three identical alpha chains.
    Biochemistry, 1971, Apr-27, Volume: 10, Issue:9

    Topics: Alanine; Amino Acids; Aminopropionitrile; Animals; Carbohydrates; Cartilage; Chickens; Chromatograph

1971
Experimental lathyrism: inhibition of beta-alanine incorporation by beta-aminopropionitrile.
    Experientia, 1971, Oct-15, Volume: 27, Issue:10

    Topics: Alanine; Aminopropionitrile; Carbon Isotopes; Cell Line; Cells, Cultured; Fibroblasts; Lathyrism

1971
The demonstration of a possible common mechanism of lathyrogenic activity.
    Biochemical and biophysical research communications, 1966, Apr-19, Volume: 23, Issue:2

    Topics: Alanine; Butylamines; Chemical Phenomena; Chemistry; Collagen; Cyanides; Furaldehyde; Hydrazines; La

1966