alanine and Lathyrism
alanine has been researched along with Lathyrism in 13 studies
Alanine: A non-essential amino acid that occurs in high levels in its free state in plasma. It is produced from pyruvate by transamination. It is involved in sugar and acid metabolism, increases IMMUNITY, and provides energy for muscle tissue, BRAIN, and the CENTRAL NERVOUS SYSTEM.
alanine : An alpha-amino acid that consists of propionic acid bearing an amino substituent at position 2.
Lathyrism: A paralytic condition of the legs caused by ingestion of lathyrogens, especially BETA-AMINOPROPIONITRILE or beta-N-oxalyl amino-L-alanine, which are found in the seeds of plants of the genus LATHYRUS.
Research Excerpts
| Excerpt | Relevance | Reference |
|---|---|---|
| "beta-N-Oxalylamino-L-alanine (BOAA) and beta-N-methylamino-L-alanine (BMAA) are chemically related excitant amino acids isolated from the seed of Lathyrus sativus (BOAA) and Cycas circinalis (BMAA), consumption of which has been linked to lathyrism (an upper motor neuron disorder) and Guam amyotrophic lateral sclerosis (ALS), respectively." | 3.67 | Discovery and partial characterization of primate motor-system toxins. ( Hugon, J; Ludolph, A; Nunn, PB; Ross, SM; Roy, DN; Schaumburg, HH; Spencer, PS, 1987) |
Research
Studies (13)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (76.92) | 18.7374 |
| 1990's | 1 (7.69) | 18.2507 |
| 2000's | 1 (7.69) | 29.6817 |
| 2010's | 1 (7.69) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Haque, RM | 1 |
| Kuo, YH | 1 |
| Lambein, F | 2 |
| Hussain, M | 1 |
| RESSLER, C | 2 |
| NELSON, J | 1 |
| PFEFFER, M | 1 |
| Brennan, L | 1 |
| Alves, PM | 1 |
| Hewage, C | 1 |
| Malthouse, JP | 1 |
| McBean, GJ | 1 |
| Malathi, K | 1 |
| Padmanaban, G | 1 |
| Rao, SL | 1 |
| Sarma, PS | 1 |
| Riepe, M | 1 |
| Spencer, PS | 4 |
| Ludolph, AC | 1 |
| Allen, CN | 1 |
| Roy, DN | 3 |
| Ludolph, A | 2 |
| Hugon, J | 2 |
| Dwivedi, MP | 1 |
| Schaumburg, HH | 2 |
| Nunn, PB | 2 |
| Ross, SM | 2 |
| Seelig, M | 1 |
| Miller, EJ | 1 |
| Tschiersch, B | 1 |
| Aleo, JJ | 1 |
| Cammarata, A | 1 |
| Bensusan, HB | 1 |
| McKnight, SD | 1 |
| Naidu, MS | 1 |
Reviews
1 review available for alanine and Lathyrism
| Article | Year |
|---|---|
[Toxic amino acids. A report].
Topics: Alanine; Amino Acids; Animals; Bacillus; Canavanine; Cycloserine; Fungi; Lathyrism; Plants; Rats | 1966 |
Other Studies
12 other studies available for alanine and Lathyrism
| Article | Year |
|---|---|
Effect of environmental factors on the biosynthesis of the neuro-excitatory amino acid β-ODAP (β-N-oxalyl-L-α,β-diaminopropionic acid) in callus tissue of Lathyrus sativus.
Topics: Alanine; Amino Acids, Diamino; Excitatory Amino Acids; Isoxazoles; Lathyrism; Lathyrus; Micronutrien | 2011 |
A PYRIDOXAL-BETA-CYANOALANINE RELATION IN THE RAT.
Topics: Alanine; Amino Acids; Anticonvulsants; Chromatography; Cysteine; Enzyme Inhibitors; Lathyrism; Pepti | 1964 |
Isolation and identification from common vetch of the neurotoxin beta-cyano-L-alanine, a possible factor in neurolathyrism.
Topics: Alanine; Cyanides; Herbicides; Lathyrism; Nervous System; Neurotoxins; Plants; Vicia sativa | 1962 |
Impact of the gliotoxin L-serine-O-sulphate on cellular metabolism in cultured rat astrocytes.
Topics: Alanine; Alanine Transaminase; Animals; Animals, Newborn; Aspartate Aminotransferases; Astrocytes; C | 2006 |
Studies on the biosynthesis of beta-N-oxalyl-L-alpha, beta-diaminopropionic acid, the Lathyrus sativus neurotoxin.
Topics: Adenosine Triphosphate; Alanine; Amino Acids; Carbon Isotopes; Chromatography, Paper; Coenzyme A; El | 1967 |
In vitro toxicological investigations of isoxazolinone amino acids of Lathyrus sativus.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Alanine; Aminobutyrates; Animals; Electrophysiology; Hippocamp | 1995 |
Lathyrism: evidence for role of the neuroexcitatory aminoacid BOAA.
Topics: Adolescent; Adult; Alanine; Amino Acids, Diamino; Animals; beta-Alanine; Central Nervous System; Chi | 1986 |
Discovery and partial characterization of primate motor-system toxins.
Topics: Alanine; Amino Acids, Diamino; Animals; beta-Alanine; Cyanobacteria Toxins; Humans; Lathyrism; Macac | 1987 |
Detection and characterization of plant-derived amino acid motorsystem toxins in mouse CNS cultures.
Topics: Alanine; Amino Acids, Diamino; Animals; beta-Alanine; Cell Survival; Cells, Cultured; Central Nervou | 1987 |
Isolation and characterization of a collagen from chick cartilage containing three identical alpha chains.
Topics: Alanine; Amino Acids; Aminopropionitrile; Animals; Carbohydrates; Cartilage; Chickens; Chromatograph | 1971 |
Experimental lathyrism: inhibition of beta-alanine incorporation by beta-aminopropionitrile.
Topics: Alanine; Aminopropionitrile; Carbon Isotopes; Cell Line; Cells, Cultured; Fibroblasts; Lathyrism | 1971 |
The demonstration of a possible common mechanism of lathyrogenic activity.
Topics: Alanine; Butylamines; Chemical Phenomena; Chemistry; Collagen; Cyanides; Furaldehyde; Hydrazines; La | 1966 |